European PostASCO Meeting 2011

European PostASCO Meeting 2011 Course Directors Axel Hauschild, MD Claus Garbe, MD Interdisciplinary Global Conference on Developing New Treatments for Melanoma Second announcement July 7 th 8 th, 2011 Munich, Germany Leonardo Royal Hotel www.melanomaglobal2011.org E A D O Under the auspices of the European Association of Dermato-Oncology and ADO/DeCOG

Foreword Dear colleagues and friends, metastatic melanoma is still considered as a disease that is extremely hard to treat. It shows a dismal prognosis and mainly effects middle-aged women and men. The current treatment options apart from clinical trial participation are very limited. New treatment modalities for this disease have not been approved for decades. However, we are expecting a significant improvement of the treatment options for melanoma in the near future. Numerous new therapies are emerging for the adjuvant treatment of high-risk melanoma patients, such as for non-resectable metastatic melanoma patients. New immunotherapeutic and targeted agents will be used either apart, or in combination. In addition to conventional chemotherapy, intralesional and loco-regional treatment methods are still of important value. However, it will be the main target for all of us to choose the right patients for the right drugs! The aim of the Interdisciplinary Global Conference on Developing New Treatments for Melanoma in Munich is to grant a deep overall insight into the development of new drugs for melanoma. The lively interaction of clinicians, as well as experts in translational and basic research, and representatives of the pharmaceutical industry, guarantees a successful outcome for every participant. International key opinion leaders will be invited to give an overview throughout specified presentations, to present latest clinical trial results, and to discuss on exciting new drugs with the audience at roundtables. In addition to the scientific value of this meeting, every participant may seize the given opportunity to interact with experts in a familiar setting in one of the most interesting cities of Germany. Please join us for this melanoma event and submit your own studies and case presentations as free communications and as posters. We look forward to welcoming you in Munich in July 2011! Axel Hauschild, MD Conference President Claus Garbe, MD Conference President 3

Thursday, July 7 th 4 8:00 12:00 Pre-congress time slots for study/advisory meetings 12:00 Opening of the Conference EADO Presidential Address Jean-Jacques Grob, Marseille, France 12:10 14:00 SYMPOSIUM I Melanoma classification for treatment decisions Chairpersons: Jean-Jacques Grob, Marseille, France Hubert Pehamberger, Vienna, Austria 12:10 12:28 AJCC classification: New indications for treatment decisions? Vernon Sondak, Tampa, USA 12:32 12:50 Assessment and reproducibility of ulceration and mitotic rate Rudolf Stadler, Minden, Germany 12:54 13:12 Molecular classification of melanoma: ready for prime time? Dirk Schadendorf, Essen, Germany 13:16 13:34 Biomarkers for interferon responsiveness Helen Gogas, Athens, Greece 13:38 13:56 Proliferation versus invasion: what is driving melanoma progression? Reinhard Dummer, Zurich, Switzerland 14:00 14:30 COFFEE BREAK 14:30 15:30 SATELLITE SYMPOSIUM I (MSD) What s your opinion about adjuvant melanoma treatment? An interactive symposium. Chairperson: Axel Hauschild, Kiel, Germany 14:30 14:46 Update on SLND and selecting patients for adjuvant therapy Vernon Sondak, Tampa, USA 14:50 15:06 Rationale for current and new adjuvant treatment modalities: pegylated IFN, high-dose IFN, ipilimumab, MAGE-A3 ASCI or combinations? John Kirkwood, Pittsburgh, USA 15:10 15:26 Case presentations/interactive questions and answers Axel Hauschild, Kiel, Germany 15:30 16:00 KEY NOTE LECTURE Chairpersons: Friedegund Meier, Tuebingen, Germany Alexander Stratigos, Athens, Greece 15:30 16:00 Update on melanoma stem cells Meenhard Herlyn, Philadelphia, USA

Thursday, July 7 th 16:00 17:00 SYMPOSIUM II Panel Discussion: Gene mutation testing and reimbursement issues Chairpersons: Alexander Enk, Heidelberg, germany Andreas Mackensen, Erlangen, germany 16:00 16:12 What can we learn from molecular testing of lung cancer? Reinhard Büttner, Bonn, Germany 16:15 16:27 Gene mutation testing: How I do it Jürgen Bauer, Tuebingen, Germany 16:30 16:42 BRAF Jeffrey Lawrence, Pleasanton, USA 16:45 16:57 c-kit Carola Berking, Munich, Germany 16:00 18:00 Free Communications r1+r2 Chairpersons: Helen Gogas, Athens, Greece Josep Malvehy, Barcelona, Spain 17:00 18:00 SATELLITE SYMPOSIUM II (Roche) Chairperson: Axel Hauschild, Kiel, Germany 17:00 17:16 Hedgehog pathway inhibition as a new therapeutic approach in cancer Caroline Robert, Paris, France 17:20 17:36 Vismodegib in basal cell carcinoma Dirk Schadendorf, Essen, Germany 17:40 17:56 Patient cases Axel Hauschild, Kiel, Germany 18:00 19:00 SATELLITE SYMPOSIUM III r1+r2 (Swedish Orphan Biovitrum AB) Interferon-alpha in Melanoma New Approaches Chairperson: Rudolf Stadler, Minden, Germany 18:00 18:25 Biology of human multiple subtypes of interferon-alpha Eric Lundgren, Umea, Sweden 18:30 18:55 The neoadjuvant approach and the ongoing Multiferon trial Claus Garbe, Tuebingen, Germany 18:00 19:00 GUIDED POSTER TOUR 20:00 GET TOGETHER DINNER in a Typical Bavarian beer garden 5

Friday, July 8 th 8:00 10:00 SYMPOSIUM III New Treatment Developments for Melanoma Chairpersons: Roland Kaufmann, Frankfurt, germany lev Demidov, MoscoW, Russia 08:00 08:10 Pegylated interferon-α2b (PegIntron ) Poulam Patel, Nottingham, UK 08:12 08:22 Natural interferon-α (Multiferon ) Uwe Trefzer, Berlin, Germany 08:24 08:34 Selumetinib (AZD6244) Reinhard Dummer, Zurich, Switzerland 08:36 08:46 GM-CSF John M. Kirkwood, Pittsburg, USA 08:48 08:58 OncoVex GM-CSF Robert Coffin, Woburn, USA 09:00 09:10 Tasisulam Peter Mohr, Buxtehude, Germany 09:12 09:22 Multi-VEGF inhibitor (E7080) Keith Flaherty, Boston, USA 09:24 09:34 nab-paclitaxel (Abraxane ) Axel Hauschild, Kiel, Germany 09:36 09:46 Allovectin-7 Sanjiv S. Agarwala, Bethlehem, USA 09:48 09:58 High Dose Regional Melphalan for Liver Mets James Pingpank, Pittsburgh, USA 10:00 10:15 COFFEE BREAK 10:15 11:15 SATELLITE SYMPOSIUM IV (BMS) The therapeutic landscape of advanced melanoma: recent developments and clinical implications Chairperson: Michele Maio, Siena, Italy 10:15 10:20 Welcome and introductions 10:20 10:36 The changing standard of care for patients with advanced melanoma Axel Hauschild, Kiel, Germany 10:40 10:56 How will emerging therapies influence our treatment practices and patient management? Paul Lorigan, Manchester, UK 11:00 11:15 Questions & Answers 6

Friday, July 8 th 11:15 11:45 KEY NOTE LECTURE Chairperson: Alan Spatz, Montreal, Canada 11:15 11:45 When does the presence of a target lead to treatment response? Keith Flaherty, Boston, USA 11:45 12:00 COFFEE BREAK 12:00 13:00 SATELLITE SYMPOSIUM V (Roche) (with lunch) Chairperson: Axel Hauschild, Kiel, Germany 12:00 12:16 Vemurafenib,a specific mutant B-Raf inhibitor: Mechanisms of action and result from BRIM 1 and 2 Keith Flaherty, Boston, USA 12:20 12:36 First results of the prospective-randomized phase III trial on Vemurafenib versus DTIC (BRIM-3) Axel Hauschild, Kiel, Germany 12:40 12:56 Management of cutaneous adverse events related to Vemurafenib Caroline Robert, Paris, France 13:00 15:00 SYMPOSIUM IV New Treatment Developments for Melanoma Chairpersons: Ketty Peris, l Aquila, Italy somasundaram Subramanian, MoscoW, Russia 13:00 13:10 RG7204 (PLX4032) Keith Flaherty, Boston, USA 13:12 13:22 Ipilimumab Caroline Robert, Paris, France 13:24 13:34 Bevacizumab Paul Lorigan, Manchester, UK 13:36 13:46 Imatinib/Nilotinib Jun Guo, Beijing, China 13:48 13:58 Masitinib Alain Moussy, Paris, France 14:00 14:10 MAGE-3 ASCI Brigitte Dreno, Nantes, France 14:12 14:22 Recombinant IL-21 Teresa Petrella, Toronto, Canada 14:24 14:34 Adoptive T-cell transfer Jacob Schachter, Tel Aviv, Israel 14:36 14:46 Electrochemotherapy Alessandro Testori, Milan, Italy 14:48 14:58 CAVATAK Darren Shafren, Newcastle, Australia 7

Friday, July 8 th 15:05 16:00 SYMPOSIUM V (roundtable discussion) What are the most promising combinations for the future? Chairpersons: Enrique Espinosa, Madrid, Spain Piotr Rutkowski, Warsaw, Poland 15:05 15:13 BRAF and MEK resistance Friedegund Meier, Tuebingen, Germany 15:15 15:23 Combining MAP kinase and AKT inhibition Jürgen Becker, Graz, Austria 15:25 15:33 Immunotherapy combinations Peter Hersey, Newcastle, Australia 15:35 16:00 roundtable Discussion Discussants: Jürgen Becker, Graz, Austria; Keith Flaherty, Boston, USA; Claus Garbe, Tuebingen, Germany; Peter Hersey, Newcastle, Australia; Friedegund Meier, Tuebingen, Germany; Alberto Wainstein, Belo Horizonte, Brazil 16:00 16:30 COFFEE BREAK 16:30 17:30 SATELLITE SYMPOSIUM VI (Philogen) Darleukin in Melanoma New Data CHAIRPERSON: CLAUS GARBE, TueBINGEN, GERMANY 16:30 16:46 The tumor-targeting human L19-IL2 immunocytokine Eveline Trachsel, Otelfingen, Switzerland 16:50 17:06 L19-IL2 and dacarbazine in stage IV metastatic melanoma Thomas K. Eigentler, Tuebingen, Germany 17:10 17:26 Intratumoral L19-IL2 in cutaneous melanoma metastases Benjamin Weide, Tuebingen, Germany 8

Friday, July 8 th 16:30 17:30 SYMPOSIUM VI r1+r2 Cutaneous adverse events of new anticancer drugs Chairpersons: Caroline Robert, Paris, France Judith Oláh, Szeged, Hungary 16:30 16:46 EGFR inhibitors Caroline Robert, Paris, France 16:50 17:06 Braf and MEK inhibitors Katharina C. Kähler, Kiel, Germany 17:10 17:26 Chemotherapeutic drugs Ralf Gutzmer, Hannover, Germany 17:30 18:00 KEY NOTE LECTURE Chairperson: Lars Bastholt, Odense, Denmark 17:30 18:00 How I will treat melanoma in 2015 Alexander Eggermont, Paris, France 18:00 Mini-Symposia/Time slots for advisory boards 9

Congress faculty Sanjiv S. Agarwala, MD Chief, Department of Oncology St. Luke s Cancer Center 801 Ostrum St Bethlehem, PA 180 15, USA Phone: +1 610 2970169 E-Mail: AgarwaS@slhn.org Lars Bastholt, MD Odense University Hospital Sdr. Boulevard 29 5000 Odense, Denmark Phone: +45 6 541 1738 E-Mail: lars.bastholt@ouh.fyns-amt.dk Jürgen Bauer, MD Eberhard Karls University Liebermeister Straße 25 72076 Tuebingen, Germany Phone: +49 7071 2984585 E-Mail: juergen.bauer@med. uni-tuebingen.de Jürgen Becker, MD Medical University of Graz Auenbruggerplatz 8 8036 Graz, Austria Phone: 0316 385 12538 E-Mail: juergen.becker@meduni-graz.at Carola Berking, MD Ludwig Maximilians University Frauenlobstraße 9 11 80337 Munich, Germany Phone: +49 89 51476010 E-Mail: carola.berking@med.uni-muenchen.de Reinhard Büttner, MD Professor of Pathology Department of Pathology University Hospital Bonn Sigmund-Freud-Straße 25 53127 Bonn, Germany Phone: +49 228 287-15375 E-Mail: Reinhard.Buettner@ukb.uni-bonn.de Robert Coffin, MD Chief Technology Officer and Director BioVex 34 Commerce Way Woburn, MA 01801, USA Phone: +1 781 376 4900 E-Mail: RCoffin@biovex.com Lev Demidov, MD Professor of Biotherapy Russian Academy of Medical Sciences Blokhin Cancer Center Kashirskoye Shosse 24 115478 Moscow, Russia Phone: +7 495 324 1205 E-Mail: demidov.lev@gmail.com Brigitte Dreno, MD University of Nantes CHU Nantes Place Alexis Ricordeau 44093 Cedex 01, France Phone: +33 240 083118 E-Mail: brigitte.dreno@wanadoo.fr Reinhard Dummer, MD Universitätsspital Zurich Gloriastrasse 31 CH-8091 Zurich, Switzerland Phone: +41 44 2552507 E-Mail: reinhard.dummer@usz.ch Alexander M. M. Eggermont, MD, PhD Professor of Surgery Directeur Général, Institut de Cancérologie Gustave Roussy 114 Rue Edouard Vaillant 94800 Villejuif/Paris, France Phone: +33 142 114016 E-Mail: alexander.eggermont@igr.fr Thomas Eigentler, MD Eberhard Karls University Liebermeister Straße 25 72076 Tuebingen, Germany Phone: +49 7071 2985748 E-Mail: thomas.eigentler@med. uni-tuebingen.de Alexander Enk, MD Director, University of Heidelberg Voßstraße 2 69115 Heidelberg, Germany Phone: +49 6221 56 8501 E-Mail: alexander.enk@med.uni-heidelberg.de Enrique Espinosa, MD Hospital La Paz Paseo Castellana 261 Madrid 28046, Spain Phone: +34 91 2071138 E-Mail: eespinosa00@terra.es Keith T. Flaherty, MD Director, Developmental Theraupeutics Massachusetts General Hospital Cancer Center 55 Fruit Street, Yawkey 9E Boston, MA 02114, USA Phone: 617 726-4800 E-Mail: kflaherty@partners.org 10

Congress faculty Claus Garbe, MD Eberhard Karls University Liebermeister Straße 25 72076 Tuebingen, Germany Phone: +49 7071 2987110 E-Mail: claus.garbe@med. uni-tuebingen.de Helen Gogas, MD Medical School, University of Athens 24 Karneadou STR Athens 10675, Greece Phone: +30 69 44 68 1159 E-Mail: hgogas@hol.gr Jean-Jacques Grob, MD Service de Dermatologie Hopital Ste Marguerite 270 Av Ste Marguerite 13274 Marseille Cedex 09, France Phone: +33 491 744714 E-Mail: jean-jacques.grob@mail.ap-hm.fr Jun Guo, MD Dept. Melanoma & Renal cancer Peking University School of Oncology Beijing Cancer Hospital & Research 52# Fucheng Rd, Haidian District 100142 Beijing, China Phone: 8610 88196317 E-Mail: Guoj307@126.com Ralf Gutzmer, MD Dept. of Dermatology Hannover Medical School Hauttumorzentrum Recklingerstraße 5 30449 Hannover, Germany Phone: +49 511 9246-0 E-Mail: rgutzmer@gmx.de Axel Hauschild, MD University of Kiel Schittenhelmstraße 7 24105 Kiel, Germany Phone: +49 431 5971852 E-Mail: ahauschild@dermatology.uni-kiel.de Meenhard Herlyn, MD Associate Director for Translational Research Wistar Institute Cancer Center 3601 Spruce St. Philadelphia, PA 19104, USA Phone: +1 215-898-3950 E-Mail: herlynm@wistar.org Peter Hersey, MD Department of Oncology Room 443 Newcastle University David Madison Building Cnr King And Watt Sts Newcastle NSW 2300, Australia Phone: +61 2 19236828 E-Mail: Peter.Hersey@Newcastle.edu.au Katharina C. Kähler, MD University of Kiel Schittenhelmstraße 7 24105 Kiel, Germany Phone :+49 431 5971852 E-Mail: kckaehler@yahoo.de Roland Kaufmann, MD, Director Clinical Center J. W. Goethe University Theodor-Stern-Kai 7 60590 Frankfurt/Main, Germany Phone: +49 69 63015311 E-Mail: kaufmann@em.uni-frankfurt.de John M. Kirkwood, MD Usher Professor of Medicine and Dermatology University of Pittsburgh School of Medicine Director, Melanoma and Skin Cancer Program University of Pittsburgh Cancer Institute Hillman Research Suite L1.32c 5115 Centre Avenue Pittsburgh PA 15213-2584, USA Phone: +1 412 6237707 E-Mail: KirkwoodJM@upmc.edu H. Jeffrey Lawrence, MD Senior Director, Medical & Scientific Affairs Genomics & Oncology Roche Molecular Systems, Inc. 4300 Hacienda Drive Pleasanton, CA 94588, USA Phone: +1 925 730 8474 E-Mail: jeffrey.lawrence@roche.com Paul Lorigan, MD, FRCP Senior Lecturer and Consultant in Medical Oncology School of Cancer and Imaging Sciences University of Manchester c/o The Christie NHS Foundation Trust Wilmslow Road, Withington Manchester M20 4BX, UK Phone: +44 161 446 8002 E-Mail: paul.lorigan@christie.nhs.uk Erik Lundgren, MD, PhD Professor of Molecular Biology University of Umea Umea, Sweden S-90187 Phone: +46 90 133536 E-Mail: erik.lundgren@molbiol.umu.se 11

Congress faculty Andreas Mackensen, MD Director, Department of Medical Oncology Universitätsklinikum Erlangen Medizinische Klinik 5 Hämatologie und Internistische Onkologie Krankenhausstr. 12 91054 Erlangen, Germany Phone: +49 9131 85 35955 E-Mail: andreas.mackensen@uk-erlangen.de Michele Maio, MD Department of Oncology University Hospital of Siena Strada delle Scotte n 14 53100 Siena, Italy Phone: +39 577 586336 E-Mail: mmaio@cro.it Josep Malvehy, MD Coordinator of the Melanoma Unit Hospital Clínico de Barcelona C/Villarroel 170.08036 Barcelona, Spain Phone: +34 93 22754002422 E-Mail: JMALVEHY@clinic.ub.es Friedegund Meier, MD Eberhard Karls University Liebermeister Straße 25 74076 Tuebingen, Germany Phone: +49 7071 2984500 E-Mail: friedegund.meier@t-online.de Peter Mohr, MD Center of Dermatology Elbeklinikum Buxtehude Am Krankenhaus 1 21614 Buxtehude, Germany Phone: +49 4161 7036209/-6250 E-Mail: Peter.Mohr@elbekliniken.de Alain Moussy, MD CEO, AB Science 3, av George V 75008 Paris, France Phone : +33 147202311 E-Mail : a.moussy@ab-science.com Judith Oláh, MD and Allergology University of Szeged 6720 Szeged, Hungary E-Mail: oj@derma.szote.u-szeged.hu Poulam Patel, MD Nottingham University Hospitals City Campus Hucknell Road, Nottingham NG51PB UK Phone: +44 115 8231850 E-Mail: poulam.patel@nottingham.ac.uk Hubert Pehamberger, MD Director, University of Vienna Währinger Gürtel 18 20 1090 Vienna, Austria Phone: +43 1 404007710 E-Mail: hubert.pehamberger@ meduniwien.ac.at Ketty Peris, MD University of L Aquila Via Vetoio - Coppito 2 67100 L Aquila, Italy Phone: +39 0862433558 E-Mail: peris@univaq.it Teresa Petrella, MD Odette Cancer Center University of Toronto 2075 Bayview Ave Toronto, Ontario M4N-3M5, Canada Phone: +1 416 480 5248 E-Mail: Teresa.petrella@sunnybrook.ca James Pingpank, MD Professor of Surgery Division of Surgical Oncology University of Pittsburgh Physicians Hillman Cancer Center 5150 Centre Avenue Pittsburgh, PA 15232, USA Phone: +1 412 692 2852 E-Mail: PingpankJF@UPMC.edu Caroline Robert, MD Head of the Dermatology Unit Institute Gustave Roussy 39 rue Camille Desmoulins 94805 Villejuif Cedex, France Phone: +33 142 114210 E-Mail: caroline.robert@igr.fr Piotr Rutkowski, MD Director, Department of Soft Tissue/Bone Sarcoma and Melanoma, M. Sklodowska-Curie Memorial Cancer Center and Institute of Oncology Warsaw, Poland E-Mail: rutkowskip@coi.waw.pl Jacob Schachter, MD Sheba Medical Center Head Ella Institute for Melanoma Deputy Director Division of Oncology Tel Hashomer 52621 Israel Phone: +972 3 5302243 E-Mail: Jacob.Schachter@sheba. health.gov.il 12

Congress faculty Dirk Schadendorf, MD Director, University Hospital Essen Hufelandstraße 55 45122 Essen, Germany Phone: +49 201 7232430 E-Mail: dirk.schadendorf@uk-essen.de Darren Shafren, MD Chief Scientific Officer Viralytics Limited. Level 3, David Maddison Building Cnr King and Watt Sts Newcastle 2300, NSW Australia Phone: +61 2 49 138158 E-Mail: dshafren@mail.newcastle.edu.au Vernon Sondak, MD Professor of Surgery Chief, Division of Cutaneous Oncology Director of Surgical Education H. Lee Moffitt Cancer Center and Research Institute 12902 Magnolia Drive Tampa FL 33612, USA Phone: +1 813 7458788 E-Mail: Vernon.Sondak@moffitt.org Alan Spatz, MD Professor of Pathology and Oncology Department of Pathology Jewish General Hospital McGill University 3755 Côte Ste Catherine Road Montreal, Quebec H3T 1E2, Canada Phone: +1 514 340 8274 X 5475 E-Mail: alan.spatz@mcgill.ca Rudolf Stadler, MD Director, Medical Center Minden Hans-Nolte-Straße 1 32429 Minden, Germany Phone:+49 571 7904501 E-Mail: hautklinik@klinikum-minden.de Alexander Stratigos, MD University of Athens 28 Voucourestiou Street Athens 10671, Greece Phone: +30 210 361223 E-Mail: alstrat@hol.gr Somasundaram Subramanian, MD Director, Eurasian Oncology Program The Russian Academy of Medical Sciences 24, Kashirshoye Shosse 115478 Moscow, Russia Phone: +7 495 7711078 E-Mail: drsoma@gmail.com Alessandro Testori, MD Director Melanoma and muscle-cutaneous sarcomas Division Istituto Europeo di Oncologia Via Ripamonti 435 20141 Milan, Italy Phone: +39 02 57489459493 E-Mail: alessandro.testori@ieo.it Eveline Trachsel, MD Head of therapeutic antibody research Philochem AG Industriestrasse 30 8112 Otelfingen, Switzerland Phone: +41 44 851 57 13 E-Mail: eveline.trachsel@philochem.ch Uwe Trefzer, MD Charité Berlin Skin Cancer Center Charité Charitéplatz 1 10117 Berlin, Germany Phone: +49 30 450518016 E-Mail: uwe.trefzer@charite.de Alberto Wainstein, MD Biocancer Clinical Research Rua Amapa 3616 Belo-Horizonte, Minas Gerais 30240-060 Brazil Phone: +55 31 3224 2030 E-Mail: alberto@biocancer.com.br Benjamin Weide, MD Dept. of Dermatology Eberhard Karls University Liebermeister Straße 25 72076 Tuebingen, Germany Phone: +49 7071 2985748 E-Mail: benjamin.weide@med. uni-tuebingen.de 13

General information Congress Venue Leonardo Royal Hotel Munich, Moosacher Straße 90, 80809 München www.leonardo-hotels.com/leonardo_royal_hotel_munich Date: July 7 8, 2011 Congress Organization Mrs. Mirja Christ from MedConcept is the responsible congress organizer. Contact: MedConcept, Gesellschaft für medizinische Projekte mbh, August-Borsig-Ring 37, 15566 Schöneiche bei Berlin, Germany, Phone: +49 30 64387420, Fax: +49 30 64387435, E-Mail: info@medconcept.org or mirja.christ@medconcept.org, www.medconcept.org Hotel Accommodation Individual hotel reservation: Please contact the congress hotel or one of the hotels nearby directly for your individual room bookings. MedConcept has reserved a limited number of rooms under the reference Global Meeting 2011 in the following hotels: Leonardo Royal Hotel Munich Moosacher Str. 90, 80809 Munich Phone: +49 (0)89 62039779, Fax: +49 (0)89 62039717, E-mail: info.royalmunich@leonardo-hotels.com Rate per standard room and night: 129 E single and 149 E double, breakfast included Booking deadline: May 28, 2011 NH München Deutscher Kaiser Arnulfstr. 2, 80335 Munich Phone: +49 (0)89 54530, Fax: +49 (0)89 54532255, E-mail: nhdeutscherkaiser@nh-hotels.com Rate per standard room and night: 150 E single and 171 E double, breakfast included Booking deadline: May 11, 2011 Distance to Leonardo Royal Hotel: 8 km Eden Hotel Wolff Arnulfstr. 4, 80335 Munich Phone: +49 (0)89 55115-0, Fax: + 49 (0)89 55115-555, E-mail: info@ehw.de Rate per standard room and night: 129 E single and 165 E double, breakfast included Booking deadline: June 9, 2011 Distance to Leonardo Royal Hotel: 6 km Four Points By Sheraton München Olympiapark Helene-Meyer-Ring 12, 80809 Munich Phone: +49 (0)89 357510, Fax: +49 (0)89 35751800, E-mail: olympiaparkmuenchen@fourpoints.com Rate per standard room and night: 109 E single and 128 E double, breakfast included Booking deadline: May 25, 2011 Distance to Leonardo Royal Hotel: 1 km All booking of rooms only according to availability! All rates include 19 % VAT! 14

General information Language and translation The official language of the meeting will be English. Simultaneous translation will not be provided. Exhibition A Commercial Exhibition will be held at the Congress Venue, close to the main meeting rooms. If you are interested in participating as an exhibitor, please contact MedConcept s secretariat for further information. Fees (VAT included) Early registration: till May 6 th From May 7 th till June 24 th On site Full Delegates 300 Euro 400 Euro 500 Euro Residents (doctor-in-training) 200 Euro 250 Euro 300 Euro Eastern European Countries 200 Euro 250 Euro 300 Euro Day Ticket July 7 th July 8 th 150 Euro 200 Euro 250 Euro If more than one member of the same institution registers a special early registration fee of 250 Euro per person (Full Delegates) and 150 Euro per person (Residents and Eastern European Countries) will be honored for all participants belonging to this institution. This offer is only valid if participants can proof that multiple members of this institution have registered. Should our sponsors wish to purchase 10 tickets or more we would like to offer a special discount. Please contact us for further information. Get-Together Dinner In a typical Bavarian beer garden July 7th, 2011, 20:00 h Augustiner Keller, Arnulfstr. 52, 80335 Munich Phone +49 (0)89 594393, www.augustinerkeller.de This informal get-together will be the perfect opportunity to meet and socialize with other delegates. Beverages and a typical Bavarian buffet will be provided. Transportation will be provided from the Leonardo Royal Hotel to the Augustiner Keller at 19:30h and 19:45h. Transportation back to the Leonardo Royal Hotel will be at 22:30 h, 23:30 h and 00:30 h. Price per person: 50 Euro incl. VAT (Please note that the number of tickets is limited.) 15

General information Cancellation policy Cancellations must be received in writing by July 1, 2011. No refunds will be granted after that date; however, you may transfer your registration to a colleague. An administrative fee of 30 Euro will be assessed for cancellations received at any time. The participant acknowledges that he/she has no right to lodge damage claims against the organizers should the holding of the meeting be hindered or prevented by unexpected, political or economic events or generally by force, or should the non-appearance of speakers or other reasons need program changes. With registration, the participant accepts this proviso. Insurance The Organizer does not accept liability for individual medical, travel or personal insurance and participants are strongly advised to make their own arrangements in respect to health and travel insurance. Passport and visa For most nationalities visas are not required for entering Germany. For further information about visa and passport please contact the German embassy in your country. If an invitation letter for visa purposes is required please contact MedConcept. Abstracts Deadline Abstract Submission: May 30, 2011 Abstracts will be considered for Poster Presentation as part of the Poster Discussion Sessions. Selected abstracts will be chosen for an oral presentation during the Free Communications Sessions. Please visit www.melanomaglobal2011.org for further information. Congress organisation by: MedConcept Gesellschaft für medizinische Projekte mbh August-Borsig-Ring 37 15566 Schöneiche bei Berlin Phone +49 30 64387420 Fax +49 30 64387435 info@medconcept.org www.medconcept.org

REGISTRATION FORM July 7th 8th, 2011 European PostASCO Meeting 2011 Interdisciplinary Global Conference on Developing New Treatments for Melanoma First Name: Last Name: Professional Title: Degree: MD PhD RN PA-C Other Gender: Male Female Birth Date (YY/MM/DD) Speciality: Institution: Mailing address: City: State: Zip Code: Country: Daytime Telephone: Fax: E-Mail: Fees (VAT included) Early registration: till May 6 th From May 7 th till June 24 th On site Full Delegates 300 Euro 400 Euro 500 Euro Residents (doctor-in-training) 200 Euro 250 Euro 300 Euro Eastern European Countries 200 Euro 250 Euro 300 Euro Day Ticket July 7 th July 8 th 150 Euro 200 Euro 250 Euro If more than one member of the same institution registers a special early registration fee of 250 Euro per person (Full Delegates) and 150 Euro per person (Residents and Eastern European Countries) will be honored for all participants belonging to this institution. This offer is only valid if participants can proof that multiple members of this institution have registered. No. of acc. persons: names: No. of Tickets for Get-Together-Dinner, July 7th, Beer Garden (50 Euro): Total Amount (registration fee/dinner): Euro Payment Method Invoice: Credit Card: MasterCard Visa American Express Credit Card Number: Expiration Date: Security Code CCV: (MC/Visa 3 digits on back, AMEX 4 digits on front) Cardholder Name: Signature: To Register Mail Registration form and payment to: MedConcept GmbH, August-Borsig-Ring 37, 15566 Schöneiche bei Berlin, Germany Fax Registration to: +49 30 64387435 Register online: www.melanomaglobal2011.org For more information: Please contact Mirja Christ E-Mail: info@medconcept.org MedConcept Gesellschaft für medizinische Projekte mbh

sponsors Gold Bronze Philogen innovating targeting Further Sponsors AB Science BioVex Celgene DCS Innovative Diagnostik-Systeme Delcath Systems IGEA S.p.A. Lilly Deutschland medac Spirig Pharma Vical Incorporated Viralytics

Erdgeschoss/Ground Floor Terrasse/terrace R6 R7 R5 R4 Speaker- Preview- Room R3 R2 R1 Service Terrasse/terrace Service künstlicher Wasserlauf/ artificial water point Foyer Business Center Einfahrt Tiefgarage/ access underground parking WC/ toilet Davidoff Lounge Lifts Registration Desk Lobby Reception Desk Back Office Moosacher Straße 90 Hoteleingang/ hotel entrance Leonardo Royal Hotel Munich Untergeschoss/Basement