Curriculum Vitae. Istanbul University, Institute for Experimental Medical MSc. Istanbul University, Institute for Experimental Medical

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1 Curriculum Vitae Name Elif Ugurel Address Selimiye Kisla cad. No: 11/5 Uskudar/Istanbul GSM Date of birth Nationality Turkish Education PhD Istanbul University, Institute for Experimental Medical (ongoing) Research, Genetics Department MSc. Istanbul University, Institute for Experimental Medical Research, Genetics Department Bachelor Istanbul University, Cerrahpasa Faculty of Medicine, Medical Biological Science High School Bursa Milli Piyango Anatolian High School Internships October 2004 Cerrahpasa Faculty of Medicine, Central Biochemistry Laboratory November January 2005 Istanbul University, Institute for Experimental Medical Research, Molecular Medicine Department March 2005 Cerrahpasa Faculty of Medicine, Microbiology Department April-June 2005 Cerrahpasa Faculty of Medicine, Department of Children Health, Immunology Laboratory

2 November 2005-June 2006 Istanbul University, Institute for Experimental Medical Research, Genetics Department Scientific Research Projects 2009 Master of Science Thesis Screening of Patients with Behçet s Disease by ELISA Method with Proteins Expressed by Cloning of PINK1 and SWAP70 Genes (BAP No: TUBITAK Project Identifying of Autoreactive Antigens in Neuro- Behçet s Patients by SEREX Method (TUBITAK No: 108S053) PhD Thesis Evaluation of Complexin1 Gene Expression and micrornas Target This Gene in Neuro-Behçet s Patients (BAP No: 25413) BAP Project Gene Expression Profiles in Vascular and Parenchymal Sub-types of Neuro-Behçet s Disease Honours and Awards 2009 Second award of best oral presentation: Elif Uğurel, Burçak Vural, Sema İçöz, Erdem Tüzün, Murat Kürtüncü, Filiz Çavuş, Ahmet Gül, Ali O. Güre, Uğur Özbek, Mefküre Eraksoy, Gülşen Akman-Demir. Anti-neuronal Antibodies in Neuro-Behçet s Disease. 45. National Congress of Neurology. Antalya, Turkey 2010 Second award of best oral presentation: Pınar Saip, Fatma Şen, Burçak Vural, Elif Uğurel, Ayşe Demirkan, Duygu Derin, Yeşim Eralp, Hakan Çamlıca, Zeki Üstüner, Uğur Özbek. Association Between Glutathione S-transferase P1 Polymorphisms and Time to Tumor Progression in Small Cell Lung Cancer. 3. Medical Oncology Congress. Antalya, Turkey

3 Scholarships TUBITAK (Turkish Organization of Science and Technical Research) scholarship for research project titled ''Evaluation of Autoreactive Antigens in Neuro-Behçet s Disease by SEREX Method'' (Project Number: 108S053) Courses and Certificates November 2004 ''Using of Test Animals in Medicine'', Cerrahpasa Faculty of Medicine of Istanbul University, Istanbul, Turkey /03/2008 ''Using of Light Cycler 480'', Roche Diagnostics, Istanbul, Turkey 10-11/12/2009 ''Basics and Application Examples of Proteomic Research'', TUBITAK MAM-Turkish Association of Biochemistry and Istanbul Bilim University, Istanbul, Turkey Workshops 15-17/04/2011 ''Advances in Immunology and Cancer Biology'', Bogazici University, Istanbul, Turkey 14-16/06/2012 EMBO Young Scientists Forum, Yeditepe University, Istanbul, Turkey Languages English 25/02/2011 IELTS (International English Language Testing System) Computer Skills Microsoft Office for Windows CLC Main Workbench 4 GraphPad Prism 5 with an average score of 6,5 (max. score 9) in Istanbul, Turkey.

4 Scientific Publications 2009 Vural B, Demirkan A, Ugurel E, Kalaylioglu-Wheeler Z, Esen BA, Gure AO, Gül A, Ozbek U.. Seroreactivity against PTEN-induced putative kinase 1 (PINK1) in Turkish patients with Behçet's disease. Clin Exp Rheumatol Mar-Apr;27(2 Suppl 53):S Vural B, Yakar F, Derin D, Saip R, Yakar A, Demirkan A, Karabulut A, Ugurel E, Cine N, Kılıcaslan Z, Tuzun E, Ozbek U. Evaluation of Glutathione S-Transferase P1 Polymorphisms (Ile105Val and Ala114Val) in Patients with Small Cell Lung Cancer. Genet Test Mol Biomarkers Jul;16(7): Vural B, Uğurel E, Tüzün E, Kürtüncü M, Zuliani L, Cavuş F, Içöz S, Erdağ E, Gül A, Güre AO, Vincent A, Ozbek U, Eraksoy M, Akman-Demir G. Antineuronal and stress-induced-phosphoprotein 1 antibodies in neuro-behçet's disease. J Neuroimmunol Oct 28;239(1-2): Erdağ E, Tüzün E, Uğurel E, Cavuş F, Sehitoğlu E, Giriş M, Vural B, Eraksoy M, Akman-Demir G. Switch-associated protein 70 antibodies in multiple sclerosis: relationship between increased serum levels and clinical relapse. Inflamm Res Sep;61(9): Elif Ugurel, Aydın Karabulut, Ahmet Gul, Ali O. Gure, Erdem Tuzun, Ugur Ozbek, Burcak Vural. Investigation of SWAP70 Antibody in Patients with Behçet s Disease. Deneysel Tip Dergisi Cilt 2, Sayı 4, Sayfa Kurtuncu M, Kaya D, Zuliani L, Erdag E, Icoz S, Ugurel E, Cavus F, Aysit N, Birisik O, Vincent A, Eraksoy M, Vural B, Akman-Demir G, Tuzun E. CACNA1H antibodies associated with headache with neurological deficits and cerebrospinal fluid lymphocytosis (HaNDL). Cephalalgia Jan;33(2): Presentations in International Meetings 2007 Emrah Yücesan, Snezana Maljevic, Nerses Bebek, Betül Baykan, Elif Uğurel, İnci Özyer, Naci Çine, Özkan Özdemir, Holger Lerche, Uğur Özbek. Determination of E352K mutation in the GABA receptor alpha-subunit causing juvenile myoclonic epilepsy. Idiopathic Generalized Epilepsies (IGE):

5 Developmental Aspects; Bridging Basic Science and Clinical Research, Antalya, Turkey, (Poster) 2009 Elif Uğurel, Burçak Vural, Ayşe Demirkan, Ali O. Güre, Ahmet Gül, Uğur Özbek. Seroreactivity Against PTEN-Induced Putative Kinase 1 (PINK1) in Turkish Patients With Behçet s Disease. Mediterranean Medical Genetics Meeting, Ankara, Turkey, (Poster) 2010 P. Saip, F. Sen, B. Vural, E. Uğurel, A. Demirkan, D. Derin, Y. Eralp, H. Çamlıca, Z. Üstüner, U. Özbek. Association Between Glutathione S-transferase P1 Polymorphisms and Time To Tumor Progression In Small Cell Lung Cancer Patients. ASCO Annual Meeting, Chicago, USA, (Poster) 2010 Elif Uğurel, Burçak Vural, Uğur Özbek, Ahmet Gül, Ali O. Güre. Antibody Responses Against PINK1 and SWAP70 Antigens in Behçet s Disease. 14th International Conference on Behçet s Disease, London, UK, (Poster) 2010 Akman-Demir G, Tüzün E, Kaya D, Vural B, Uğurel E, İçöz S, Eraksoy M, Vincent A, Ertas M, Kürtüncü M. Headache and Neurological Deficits With Cerebrospinal Fluid Lymphocytosis (HaNDL): Could It Be An Autoimmun Disease? 62nd Annual Meeting of the American-Academy-of-Neurology. Toronto, Canada. April 10-11, (Poster) 2011 Akman-Demir G, Vural B, Ugurel E, İçöz S, Tüzün E, Kürütüncü M, Çavuş F, Özbek U, Eraksoy M. Anti-Neuronal and Stress-Induced-Phosphoprotein 1 Antibodies In Neuro-Behçet s Disease. 63rd AAN Annual Meeting, Honolulu, HI. April 09-16, (Poster) 2012 Erdag E, Ugurel E, Cavus F, Vural B, Kurtuncu M, Eraksoy M, Akman-Demir G, Tuzun E. Elevated Switch-Associated Protein 70 (SWAP70) Antibody Levels during Attacks in Multiple Sclerosis Patients. 64th Annual Meeting of the American-Academy-of-Neurology (AAN), New Orleans, April 21-28, (Poster)

6 Presentations in National Meetings 2006 Demirkan A., Vural B., Ugurel E., Derin D., Öztürk Açıkalın B., Saip P., Özbek U. Evaluation of promotor region of retinoic acid receptor-gene in small cell lung cancer patients. 7. National Congress of Prenatal Diagnosis and Medical Genetics, Kayseri, Turkey, (Poster) 2008 Elif Ugurel, Burçak Vural, Ayse Demirkan, Fatih Yakar, Duygu Derin, Pınar Saip, Aysun Yakar, Naci Çine, Zeki Kılıçaslan, Ugur Özbek. Evaluation of GSTP1 Polymorphisms(Ile105Val ve Ala114Val)in COPD and SCLC Patients. 8. National Congress of Medical Genetics, Çanakkale, Turkey, (Poster) 2009 Elif Ugurel, Burçak Vural, Ayse Demirkan, Ali O. Güre, Ahmet Gül, Ugur Özbek. PTEN-Induced Putative Kinase 1 (PINK1) Seroreactivity in Behçet's Disease Patients. I. DETAE Days, Istanbul, Turkey, (Poster) 2009 Elif Ugurel, Burçak Vural, Sema Içöz, Erdem Tüzün, Murat Kürtüncü, Filiz Çavus, Ahmet Gül, Ali O. Güre, Ugur Özbek, Mefküre Eraksoy, Gülsen Akman-Demir. Anti-neuronal Antibodies in Neuro-Behçet's Disease. 45. National Congress of Neurology, Antalya, Turkey, (Oral) 2010 P. Saip, F. Sen, B. Vural, E. Ugurel, A. Demirkan, D. Derin, Y. Eralp, H. Çamlıca, Z. Üstüner, U. Özbek. Association Between Glutathione S-transferase P1 Polymorphisms and Time To Tumor Progression In Small Cell Lung Cancer Patients. 3. National Congress of Oncology, Antalya, Turkey, (Oral) 2011 Elif Uğurel, Filiz Çavuş, Burçak Vural, Erdem Tüzün, Murat Kürtüncü, Sema İçöz, Ece Erdağ, Ahmet Gül, Ali O. Güre, Uğur Özbek, Mefkure Eraksoy, Gülşen Akman Demir. Anti-STIP1 Antibody in Neuro-Behçet s Disease. 21. National Congress of Immunology, Marmaris, Turkey, (Oral) 2011 Uğurel E, Vural B, Tüzün E, Kürtüncü M, Zuliani L, Cavuş F, Içöz S, Erdağ E, Gül A, Güre AO, Vincent A, Ozbek U, Eraksoy M, Akman-Demir G. Antineuronal and stress-induced-phosphoprotein 1 antibodies in neuro-behçet's disease. 47. National Congress of Neurology, Antalya, Turkey, (Oral)

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