63 Countries. At the heart of decision-making

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2 1969 Founded 501 M Turnover 63 Countries 4,696 Workforce 1995 Euronext Paris At the heart of decision-making Cegedim develops exclusive databases and high value-added software solutions. The Group has 2 major operational divisions: «Healthcare and strategic data», which comprises solutions specifically designed for pharmaceutical companies, healthcare sector professionals and health insurance providers. «Technologies and services», which covers a variety of sectors. Established as the European leader in its historic core business, Cegedim provides the world s largest pharmaceutical companies with vital support for successful CRM (Customer Relationship Management) and helps measure sales and marketing effectiveness. Cegedim s CRM tools, enhanced by the Group s strategic databases, provide marketing and sales departments with a clearer picture of their market and targets, in order to optimize their strategies and return on investment. Cegedim has also positioned itself as one of Europe s leading producers of medical and para-medical management software and also designs management applications dedicated to the health insurance sector. Structured, communicating and scalable, these software are integrated into the Cegedim Group s healthcare flow management systems. Capitalizing on its expertise, Cegedim offers high value-added management solutions to its numerous clients of the business sector, who are interested in outsourcing, exchanging and controlling their professional data. 1

3 A statement from the Chairman 3 Cegedim Group key figures 4 Group history 6 Two operating divisions 10 Healthcare and strategic data 12 Technologies and services 28 International operations 34 Management and human resources 36 Consolidated accounts 38 Stockmarket performance 40 Contacts 42 2

4 A statement from the Chairman Dear Sir or Madam, In 2005, and in line with its growth policy, Cegedim continued to develop its positions across the five continents. Results for 2005 are slightly above our initial forecasts. Sales rose by 15.4% to 501 million euros. Operating profit rose to 60.9 million euros, slightly above our objective of 60 million euros. Consolidated net profit grew to 37.9 million euros, at a particularly satisfying 7.6% of sales. For the first time since its creation, sales outside France exceeded one third of total sales in will see an increase in this international growth with a particularly good performance in the United States of America. In order to achieve its ambitions, Cegedim is continuing its research and development in all areas of business activity. Our American Target Suite solution is particularly adapted to the growing biotechnology market. The acquisition of the British company Compufile and the merger of our CAM and THALES businesses have allowed us to strengthen our European positions and to create a world-wide specialist in the field of Sales Force Effectiveness for the pharmaceutical industry. We have anticipated changes in the healthcare environment such as the reorganization of mutual healthcare companies, the internationalization of demand for health insurance management systems, Personal Medical File (DMP) in France, Barbuziau experimentation, a new 15% tranche of repayments amongst others. In the face of these changes we have developed our services to permanently meet the needs of our clients, the pharmaceutical industry, healthcare professionals, health insurance players and the business sector. In 2006, Cegedim will carry on this strategy with the constant objective of developing its activities and business synergies, as well as ensuring the satisfaction of its clients and employees. Jean-Claude LABRUNE Chairman and CEO 3

5 Cegedim Group key figures In million euros Turnover Operating income (EBIT) Net consolidated income Self-financing capacity Shareholders' funds attributable to the Group Net financial debt Share price as at 31 Dec. ( ) Market capitalization Turnover (in million euros) Self-financing capacity (in million euros) Operating income (in million euros) 4

6 Main consolidated ratios Operating income / Turnover 13 % 12 % Net income / Turnover 8 % 8 % Net income / Shareholders' funds 22 % 20 % Net financial debt / Shareholders' funds 61 % 68 % Net financial debt / Self-financing capacity 21 months 26 months Net income per share ( ) Gross dividend per share ( ) Market capitalization (in million euros) Net income per share (in euros) 5

7 Group history Founded in 1969 by Jean-Claude Labrune, Cegedim began as a management and documentation center for centralizing data gathered from European medical publications. Focus rapidly shifted to data collection and processing activities for the sales and marketing departments of pharmaceutical firms. The Group s objective is to provide pharmaceutical companies with the resources they need to organize and optimize sales force performance as well as to provide a full range of analyses and statistics, that enhance understanding of their market and targets. The Group has also focused increasingly on the full spectrum of healthcare professionals (doctors, pharmacists, paramedic and hospital personnel, wholesale distributors, insurance companies and third-party payers) by offering IT, communications and data interchange solutions. In so doing, the Group has established highly effective collaborative relationships, which serve further to strengthen market knowledge and ensure services remain of the highest quality. As the preferred partner of an increasing number of healthcare professionals, Cegedim is at the heart of managing healthcare flows and has been positioning itself since 2005 to face the challenges of the Personal Medical File (DMP) in France. The Group s mastery of advanced technologies relating to databases, management applications, IT, the Internet and other networks fully meets clients needs for expert know-how in this core business area. Capitalizing on its expertise, Cegedim offers high value-added management solutions to its numerous clients, who are involved in decisions about outsourcing, exchanging and controlling their professional data. CRM & strategic data 18 % Technologies and services 46 % Total Turnover insurance services Healthcare 15 % Healthcare Professionals 21 % 6

8 Revenue development by division The CRM and strategic data sector has seen revenue double since 2000 and this sector now accounts for 46% of the Group s activities. Through sustained internal and external growth the Group now covers more than 60 countries with an even wider range of solutions and services. Cegedim started to computerize healthcare professionals in France by providing doctors with practice management systems. The Group s offers were then extended to general practitioners in the UK in 1999 and to French pharmacists in These activities expanded further with the acquisition of companies producing software for doctors in the Belgian market (2003) and for pharmacists in the UK market (2004). The Healthcare insurance services sector originally provided automated payment and information exchanges solutions for third-party payers. Since 2000 the offering comprises software packages and services for healthcare insurers, extended again in 2003 and Technologies and services offerings, supported by Cegedim s core expertise, have been enriched over the years to become a diversified range of products and services that currently accounts for 18% of the Group s activities. Breakdown of turnover Division CRM and strategic data Healthcare professionals Healthcare insurance services HEALTHCARE AND STRATEGIC DATA Technologies Services TECHNOLOGIES AND SERVICES TOTAL in million euros Turnover (in million euros) Complying with IFRS for the 3 years CRM and strategic data Healthcare Professionals Healthcare insurance services Technologies Services 7

9 Group s activities evolution CRM and strategic data Healthcare professionals Creation of CEGEDIM TVF, Launch of CRM for medical reps in France ICOMED, Prescription analysis AMIX, Files update CEGERS, Sales statistics CEGEDIM BELGIUM CEGEDIM PORTUGAL CEGEDIM SPAIN CEGEDIM ITALIA ITOPS, a CEGEDIM department, Sector allocation BKL Thalès, Epidemiological panels CEGEDIM U.K. CEGEDIM -ISS* GERMANY CEGEDIM NETHERLANDS CEGEDIM SWITZERLAND CEGEDIM CZECH REPUBLIC CEGEDIM GREECE CEGEDIM HUNGARY CEGEDIM TURKEY ICOMED* BELGIUM, Prescription analysis MEDIMED GERMANY, Performance measurement INFOPHARM UK, Sales statistics SANTESURF SERVICES, Call center, training CEGEDIM POLAND INFOSANTE HUNGARY, Sales statistics CEGEDIM * EUROPE DE L'EST, Exmarket studies CEGEDIM * ROMANIA CEGEDIM SLOVAKIA CEGEDIM BRAZIL CEGEDIM AUSTRIA CEGEDIM USA Groupe CAM* et DECISIONS RESEARCH* (FRANCE, U.K., SPAIN, ITALIA, PORTUGAL, GERMANY, POLAND,CANADA, USA, ARGENTINA, AUSTRALIA, JAPAN), Auditing and business intelligence CEGEDIM * TUNISIA CEGEDIM * MEXICO, COLOMBIA, ECUADOR, GUATEMALA BKL ITALIA, Auditing and business intelligence CEGEDIM * NORWAY, DENMARK, SWEDEN, POLAND CEGEDIM RUSSIA CEGEDIM ALGERIA CAM CHINA, Auditing and business intelligence CAM PAYS DE L'EST, Auditing and business intelligence BKL UK, Auditing and business intelligence RDM Screenpharma, Doctors dedicated advertising BKL Héraclès RNP*, Advertising in pharmacies (display, merchandising) DISTAL* IN PRACTICE SYSTEMS* UK Groupe ALLIADIS* LSI* Groupe ASE* RESIP*, Pharmaceutical databases OMB Alpes* APOLINK* MEDIANE* MEDEXACT*, Scientific, medical and promotional information HDMP* BELGIUM PHARMINFOR* CEGEDIM RX* UK ENIGMA* UK SANTE GROUPE*, Distribution network EASYCOM* GERMANY TARGET SOFTWARE* USA CEGEDIM * EGYPT CEGEDIM MAROCCO BKL GERMAY, Auditing and bus iness intelligence BKL BELGIUM, Auditing and business intelligence EPIC DATABASE RESEARCH UK, Auditing and business intelligence COMPUFILE* UK, Auditing and business intelligence * Identification of external growth operations CRM DATA ROSENWALD*, Healthcare professionals directories SYNAPSE* Promotion Software for doctors Software for pharmacists

10 Healthcare insurance services Technologies and services MEDIPOST, Routing (Direct Marketing department) CCD, Head of CEGEDIM s Direct Marketing department PHARMAPOST, Printing (Direct Marketing department) 1969 à 1979 EDI, a CEGEDIM department, Computerized orders & invoices PCO CEGEDIM, Distribution and IT services DOCUBASE, Electronic management of documents 1980 à à 1989 CETIP*, Direct billing and payment flow management SOLTIM*, IT for insurers CEGEDIM SRH, Payroll and HR management PHARMASTOCK, Samples management CEGEDIM SRH SWITZERLAND, Payroll and HR management DOCUBASE SYSTEM USA, Electronic management of documents SDI*, Electronic publishing and inserting-folding (Direct Marketing department) 1990 à à 1998 CEGEDIM SRH UK, Payroll and HR management CEGELEASE, Financial leasing 1999 à 2000 COFIDATA*, Financial leasing 2001 Groupe PROVAL*, IT for insurers SELECTIS CONSULTING*, Providence, retirement programs and savings DECLARATIS, Electronic transmission gateway ASP ONE.FR*, Electronic transmission gateway HOSPITALIS*, Gateway for hospitals dedicated supply chain management APSYS NET*,Gateway for hospitals dedicated supply chain management 2002 à Payment fow and information flow Software Technologies Services 9

11 Healthcare and strategic data ONEKEY : The healthcare professionals reference CRM and strategic data Healthcare professionals Healthcare insurance services CRM - For medical reps TEAMS Companion TEAMS Call Report TEAMS Head Office TEAMS Web TEAMS Vision ATLAS ONEKEY TARGET SFA TRENDS Sales force optimization Itops Auditing, business intelligence and ROI Sales statistics CAM - THALES Studies Decisions Research Click-Pharma Infopharm Prescription analysis Icomed Studies Medimed Software for Pharmacists Alliance-Plus Premium Nexphase - UK Pharmacy Manager -UK Software and customized statistics for pharmacists Santestat Software for Doctors CrossWay Ville Doc'Ware Vision - UK Professional databases Banque Claude Bernard Rosenwald Scientific, medical and promotional information MedExact Screenpharma RNP IT for insurers Soltim - Proval Hosta Selectis Consulting Payment flow and information flow Cetip Santé-Pharma Proval CTF Electronic data interchange Edipharm Hospitalis Déclaratis ASPOne.fr Electronic transmission of treatment sheets Qualitrans - Télépharma 10

12 Technologies and services Technologies Services Electronic document management Docubase Corporate databases, CRM and associated services CCD CMP Externalized IT services PCO Cegedim Human resources management Cegedim SRH Electronic publishing / inserting-folding / logistics and routing SDI Médipost Printing Internet and hosting services Cegedim Midiway Leasing Cegelease Pharmapost Samples management Tracere 3S Pharmastock 11

13 Healthcare and strategic data The healthcare and strategic data division brings together the Cegedim Group s services which support the healthcare sector. There is a high level of synergy between the three different activities, each of which targets a different market: «CRM and strategic data» - dedicated to pharmaceutical firms «Healthcare professionals» - dedicated to doctors and pharmacists «Healthcare insurance services» - dedicated to health insurance players. CRM and strategic data Medicines are prescribed by doctors who are not direct purchasers of goods produced by the pharmaceutical industry. Pharmaceutical companies thus lack basic information regarding individual customers that is easily accessed and collected in other industries, based on ordinary client-supplier relationship. Doctors are however the key decision makers to whom pharmaceutical firms must direct their marketing in a relevant and targeted manner. Cegedim empowers pharmaceutical sales and marketing departments to better understand where, why and by whom their products are prescribed and sold. Cegedim s exclusive databases and IT solutions truly enable customers to optimize their CRM strategy and ensure them to inform the prescribing doctors with greater chances of success. Cegedim s high-performance solutions are compliant with European data protection regulations and public health codes in the countries where it operates. Cegedim provides: Tools for optimizing IT equipment and sales force effectiveness. Reporting and analysis tools for sales force. Databases and tools designed to increase knowledge about prescribers. Tools and analyzes for strategic marketing, operational marketing and business intelligence. Performance measurement tools. Promotional investment audit tools. Pharmacy order-taking tools. 12

14 Customer Relationship Management Healthcare-specific CRM tools to enhance sales and marketing effectiveness towards doctors, pharmacists and physiotherapists The success of Cegedim and its international subsidiaries is founded on recognized expertise in nominative database management. To optimize the use of these databases by clients, Cegedim develops and markets TEAMS and ONEKEY. TEAMS is the European pharmaceutical industry s most-used software and service platform in the fields of management, information and sales force effectiveness. The ONEKEY physician database is regarded as the benchmark database by the European pharmaceutical industry as well as by healthcare organizations such as specialist journals and insurance companies. Procedures for updating and clearing databases have been certified ISO 9002 since Cegedim s service offering is specifically geared to the pharmaceutical industry and highly differentiated from competitors offerings, which are essentially limited to software sales, the development of niche software or similar services offered over a smaller geographical area. In fact, Cegedim s full-service outsourcing platform features all the benefits of combining powerful technology with vast service resources. This global offering presents numerous advantages in terms of cost, performance levels and project maintenance. Without having to invest heavily in infrastructure, TEAMS users gain immediate access to essential information and tools, and Cegedim clients are empowered to mobilize their core-business resources and optimize their competitive advantages. TVF France and International subsidiaries Benefiting from a market share of some 80% in France with ONEKEY and TEAMS, the Cegedim Group has maintained its strategy of international expansion ever since the 1990s allowed Cegedim to prove the pertinence of its range with the high levels of user uptake of its latest solution, TEAMS version 7. Developed specifically to respond to organizational problems experienced by large sales forces, it has allowed Cegedim to win new major clients in numerous countries. In a very competitive market, Cegedim s market share has again increased and more than 71,000 users are now equipped with its solutions. Cegedim bought 100% of Target Software in the United States in 2005 within context of its international expansion policy. This is a new and decisive step for the future and is in line with Cegedim s ambition to become a global player in SFA (Sales Force Automation) and CRM tools for healthcare industries. Target Software has become the leading growth player for SFA and CRM tools in the North American market and equips nearly all the most successful CSOs (Contracted Sales Organizations medical visit service providers) in the United States. Everyone recognizes the value of its new technology based on MICROSOFT tools. Cegedim has also acquired the Egyptian company Trends Technology. Trends Technology markets an ETMS (Electronic Territory Management System) solution, which is available on PC and PDA and has equipped more than 1,000 medical reps in Egypt and Middle Eastern countries since Number of users worldwide With Target Software and Trends Technology, Cegedim is in a position to offer solutions for the future, relying on the ONEKEY databases and on the reinforced competences which are capable of responding to the needs of all its clients: pharmaceutical industry, CSOs or market studies providers. 13

15 Now operating in 54 countries, the Group is positioned as the supplier with the proven capacity to provide international companies with a comprehensive package that includes a full range of services and extensive geographical coverage. The ONEKEY and TEAMS solutions continue to add new functionalities adapted to constantly changing market needs. TEAMS TEAMS version 7 provides pharmaceutical company representatives and regional managers with an effective plan of action and transforms TEAMS into an even more powerful tool for sales force management. TEAMS now features micro-marketing functionalities for sales analysis and promotional campaign performance measurement. In 2005 Cegedim continued to innovate by launching two new services in order to respond to specific and increasingly strategic segments for pharmaceutical companies: TEAMS Strategic Account Management offers firms with hospital activities the option to build an action plan specific to this environment and to manage the activities of hospital reps and large account managers. TEAMS Order Management supports OTC or generic sales forces which take pharmacy orders, and integrates all the functions specific to this activity. TEAMS on a PDA platform continues to meet with great success, in a large part due to its small size, ease of use and compatibility with GPRS and UMTS transmission modes. More than 25,000 PDAs have been deployed and the solution is available in 2 versions: TEAMS Companion combines the benefits of a portable PC or a powerful workstation with the convenience and practicality of a PDA for medical reps. TEAMS Call report is designed for firms that do not equip reps with portable computers. ONEKEY ONEKEY, already firmly established in Europe, is consolidating development in key Latin America countries (Mexico, Brazil and Colombia) in order to provide clients with local or regional solutions. Recent acquisitions in Germany and in the Scandinavian countries are likewise enabling Cegedim to strengthen its leading position in the European market and to increase geographical coverage in Northern Europe. In North Africa, openings in Tunisia in 2004 and in Algeria and Morocco in 2005 have positioned Cegedim as the ideal partner for pharmaceutical industry operations in the region. Today the ONEKEY database includes more than 6.5 million healthcare professionals and 2 million potential prescribers in 26 countries. In 2005, Cegedim s constant dedication to highquality data led the company to strengthen the local teams that improve, validate and monitor database content on a daily basis using ISO 9002 certified procedures. Cegedim s pledge of quality and professionalism ensures that all sectors of the pharmaceutical industry benefit from a reliable tool, that satisfies the market s growing needs for greater productivity and greater sales force effectiveness. Consequent improvements have also been made to enrich data by supplying tactical information such as optimum call times for doctors, mailing addresses and strategic information concerning influence networks among healthcare professionals. Finally, by combining the features and resources of ONEKEY and ATLAS, Cegedim offers innovative solutions for integrating and managing the ONEKEY database in all types of information systems and technology environments. ATLAS The ATLAS portal enables pharmaceutical firms to access all necessary CRM-related information (internal data, the Cegedim databases to which the company subscribes and other external databases) and provides a flexible framework, within which the data can be consulted and combined to suit the company s needs. 14

16 ATLAS provides firms with a 360 view of their clients via a dedicated, customized and fully integrated portal. The ATLAS offer includes: ATLAS Repository: a ready-to-use marketing/sales database that incorporates valuable industry expertise. ATLAS Applications: front-office application software incorporating management rules specific to the pharmaceutical industry and designed around user-specific menus (customer service, medical information, conference management, management of legal specifications and others). ATLAS Analytics: an analytical application for headquarters, sales and marketing departments, enabling precision business management and customer segmentation strategies. Strategic partnerships with market leaders in databases and business intelligence (Microsoft, Oracle, Business Objects and others) enhance Cegedim s solutions and have contributed to making them a success with key firms in the worldwide market. Combined with ONEKEY and TEAMS, ATLAS enables companies to implement new CRM projects progressively so that legacy programs are not disrupted, past investments are not wasted and costs are reduced. Sales force optimization Itops Itops provides clients in France, Great Britain, Germany, Italy, Spain, Portugal and the Benelux countries with a service for optimizing sector allocation of sales forces. Itops is also developing auditing services, territory dimensioning services and services in determining optimum product offerings. «Itops Navi» is a new, dedicated territory-mapping tool, that features geo-coding of doctors locations and enables regional directors to analyze results in terms of sales, contact objectives and target objectives on a monthly basis. Auditing, business intelligence and ROI Cegedim Audit Marketing Mix (CAMM) A new Business Unit was created within the Cegedim Group in July 2005: Cegedim Audit Marketing Mix. It unites the expertise previously spread across the CAM, Decisions Research and THALES activities, whose operational complementarity is based on solid experience in market research, the data collection and in services to the pharmaceutical industry. Cegedim Audit Marketing Mix offers the following analyses in 36 countries: Monitoring of promotional expenditure Monitoring of prescriptions and the impact on patients health Ad-hoc quantitative and qualitative studies. This strategic information allows pharmaceutical companies to target general practitioners, specialists, pharmacists and patients. These multi-national abilities allow the requirements of 400 local clients and more than 40 international clients to be met. CAM Leader in promotional investment databases for the pharmaceutical industry, the CAM group monitors the promotional expenditures of pharmaceutical firms throughout the world on an annual basis. The CAM group is the unique global reference for 50 of the world s top pharmaceutical firms, with regard to the annual monitoring of promotional expenditure including the cost of medical visit. CAM analyses the impact and the nature of all pharmaceutically related information and communications activities targeted on doctors, in general practice or in hospitals. A staff of 160 collects data, gathered through panels comprised of over 100,000 doctors worldwide. CAM is the only international structure relying on its own local information teams to operate in 36 countries: in North and South America, Europe (including the five main markets), Asia (including Japan), the Pacific Region (including Australia) and Africa. 15

17 Decisions Research Decisions Research offers the following in 36 countries: Ad-hoc studies Powerful competitive intelligence tools. Decisions Research conducts all kinds of qualitative and quantitative market research: research into product positioning, pre-testing of communication material (sales support aids, advertising), ATUs, image reports, leaflet tests, recall tests, choice modeling with different players in the healthcare system: doctors, pharmacists, nursing staff and patients. Decisions Research (ZOOM) is the French leader for competitive intelligence in pharmaceuticals. ZOOM is also the only strategic intelligence product in the 8 largest worldwide markets, which has been translated into English. More than 800 general practitioners and specialists monitor 26 therapeutic markets. Gathering all the promotional information (medical reps, press, mailshots, conferences, studies and others), the doctors summarize this information and make a full range of competitive intelligence analyses available to pharmaceutical firms: tactical and strategic warning tools. THALES With its panels of doctors, THALES is the leading medical database based on the daily activities of doctors, representative of the national population. Historically present in France, THALES panels today consist of 1,200 general practitioners and 700 specialists: cardiologists neurologists psychiatrists gynecologists pediatricians rheumatologists gastroenterologists. 1,000 general practitioners in the United Kingdom 500 general practitioners in Italy 300 general practitioners in Belgium 500 general practitioners in Germany (1 st quarter of 2006) and soon also in Spain (end 2006). The information which is gathered continually and in real time in doctors surgeries using practice management software allows patients and doctors to be longitudinally monitored in order to analyze the prescriptions context in real-life situations. The data gathered has led to the development of a full range of studies, whose reliability has been recognized by the pharmaceutical industry and public institutions. Marketing studies: competitive analysis and assessment of opportunities, product launch and monitoring using key performance indicators and premarketing report. Promotional impact studies and ROI: measuring the impact Thales : Number of studies of promotional operations on the real prescription of doctors, analysis and optimization of the media mix, planning of commercial strategies and monitoring targets. Economic and epidemiological studies, a reflection of what happens in «real life»; frequently used by pharmaceutical companies to defend their positions in front of healthcare authorities, these studies are increasingly validated upfront by healthcare authorities. This tested method has recently been launched in the European TOP 5 markets on the basis of representative panels formed of: 16

18 Sales statistics for pharmaceutical products Cegedim SA, Sales statistics department The Sales statistics department manages the French pharmaceutical products database on behalf of GERS, France's pharmaceutical industry association. The database is compiled from statistics based on industry-wide product codes. Sales statistics are processed by region and sub-region and based on data provided by pharmaceutical firms and wholesale distributors. Since 1999, these statistics have been available online on a weekly basis. The most recent geographical segmentation was established in 1998 (746 geographical units broken down into 4,612 sub-units comprising 3 to 8 pharmacies). As the new segmentation system is much more evenly distributed in terms of business volumes, it allows pharmaceutical firms to develop true micromarketing strategies. France is one of the few countries in which the pharmaceutical industry has joined forces to produce its own statistics and the system has become a benchmark for both industry and public health authorities. France is also one of the few countries that does not use statistics produced by IMS. Cegers Cegers, a subsidiary owned 50% by Cegedim SA and 50% by GERS, offers pharmaceutical firms and industry service providers with customized studies based on sales data from a range of different sources (GERS, IMS, Nielsen, IRI, internal data and others). Cegers also provides target management (calculation and monitoring of targets, rankings, bonus calculation) for pharmaceutical companies. The customized studies are transmitted to clients on a weekly or monthly basis via various media: Click-Pharma: software that provides companyspecific customized data sheets and charts in standard pre-formatted reports. Click-Pocket: palm or pocket PC software, identical to ClickPharma. TEAMS Vision: EIS (Executive Information System) integrated into the TEAMS package. Infopharm UK / InfoSanté Romania Through its subsidiaries Infopharm UK and InfoSanté in Romania, the Cegedim Group provides sales statistics on pharmaceutical products, significantly differentiated from those offered by competing companies. Relying on Cegedim s leading market position in pharmacists software in the UK, Infopharm UK is now positioned to offer drug manufacturers an entire range of wholesale distributors sales statistics as well as a full range of sales statistics based on information collected at the pharmacy. New quantitative and qualitative studies have been deployed and perfected. InfoSanté Romania is now the market leader in regional and national sales data and provides a full range of products and services on the pharmacies and hospitals segments. Prescription analysis Icomed Icomed measures physicians preferences in drugs and treatments through up to two individually addressed questionnaires per year. More than half of all French doctors in 19 branches of medicine inform Icomed of their prescribing habits each year. This nominative data is particularly useful in defining doctor and product profiles as well as for conducting more generalized studies. Icomed Belgium began operating in 1999 and conducts specific, on-demand European-wide studies by specialty. Medimed The German company Medimed GmbH s mission is the large-scale electronic collection of nominative prescription data acquired from participating doctors. 17

19 This data, both nominative and qualitative, constitutes a particularly powerful tool for pharmaceutical firms that serves to: Define physician profiles and adapt information strategies to individual practitioners. Measure the effectiveness of promotional activities. Conduct generalized studies on markets in which companies currently operate or those they wish to enter. Despite a particularly harsh economic environment (including a government-imposed decrease of 16% in the price of medicines and the merger of client firms), Medimed s market share continued to rise in Medimed currently serves 75 pharmaceutical firms in Germany, including nearly all of the top 10 international firms. Plans to launch new studies should spur continued growth in Participating doctors benefit from the capability of monitoring their prescriptions over each quarter, to adapt prescribing habits to conform to budget constraints that may be imposed by German health authorities. Measure call quality Performance Manage sales force activity Track impact on prescription 18

20 Healthcare professionals With many years of experience dedicated to healthcare professionals, Cegedim has positioned itself as one of the leading European producers of medical and paramedical management software. The Group therefore works on a daily basis with pharmacists, general practitioners and specialists, whether they work independently or in group practices, in healthcare centers or networks. Cegedim s software responds to the needs of professionals and to the latest technical and regulatory requirements. Structured, communicative and scalable, it covers the main principles of the French Personal Medical File and more generally the exchange of patient files in most European countries. It also allows the transfer of scientific, medical and promotional information within the place of practice or between healthcare professionals. As the partner of an ever-increasing number of professionals in Europe, the Cegedim Group has reinforced its knowledge of the healthcare market, thus enhancing the excellence of the information and services which it provides. 19

21 Software for pharmacists and customized statistics for pharmacists The Cegedim Group is the European leader in the pharmacy software market with more than 14,000 pharmacy clients in France and in the United Kingdom. Alliadis Specializing in the computerization of pharmacies, the Alliadis group has been providing support to pharmacists since the computerization of the sector over 20 years ago. The Alliadis group s primary mission is to develop and market comprehensive, integrated software solutions for pharmacists, including the supply of IT equipment. Alliadis is at the forefront of the latest technological innovations and is meeting the occupational demands of its clients with high-value added solutions. This can be illustrated by the successful introduction of solutions such as Sin Etiq (electronic price display) and Clip Santé (audiovisual communications system). New regulatory challenges such as the Pharmaceutical File, the development of the SESAM-Vitale environment, the substitution objectives, and the traceability and codification of products require the development of IT tools in the short and medium term. Number of users of Alliadis By keeping a keen eye in new developments in the field, Alliadis has succeeded in adapting to the current economic environment and offers customized solutions to various market operators: Independent pharmacists: who nevertheless require communicating solutions covered by the «PharmADSL» offer. Mutual pharmacies: «Premium» s core business. Pharmacies organized in SELs (Liberal Companies): for whom the «PharmaGroup» services allow networked collaboration between fellow members. Groups of pharmacists: for whom, to date, Alliadis solutions are by far the most popular. Certain partnerships specifically allow members to benefit from exclusive IT tools adapted to the operational specialties of their group. Pharmaceutical companies: via the «PharmaLab» services. As 50 % of the flow of medical products is managed through Alliadis software applications, Alliadis is the preferred contact for leading pharmaceutical firms when implementing pharmacist-targeted information and communications projects. In France, the company has a staff of 370 with 30 offices and 2 helplines providing nationwide coverage. Strong human resources capacities enable the Alliadis group to ensure a locally based service, the excellence of which is universally acknowledged by clients. Alliadis Europe With subsidiaries Cegedim Rx and Enigma boasting a market share of approximately 50%, Alliadis entered the United Kingdom market as market leader. Retail pharmacies in the UK are entering a new era in information technology. Healthcare authorities recently granted pharmacists the right to provide certain services previously provided only by doctors, and a nationwide program to enable electronic transmission of prescriptions between doctors and pharmacies has also been launched. Retail pharmacies will be granted significant subsidies to help defray the costs of the necessary IT investment. Cegedim Rx and Enigma are in the advanced stages of issuing the requisite upgrades. The needs generated by the nationwide program ensure the two companies will continue to play a key role in the UK market. Santestat The Santestat database is compiled from data collected in pharmacies, and initial statistical results are provided through GERS, the French pharmaceutical industry association. Santestat supplies 20

22 pharmacists and groups of pharmacists with tools enabling them to optimize pharmacy management, define price strategy and monitor their purchasing markets. The Santestat database will also serve to enhance GERS internal analyses by providing pharmaceutical firms with the necessary data for monitoring pharmacy stocks and increasing their knowledge of distribution channels. Software for doctors and paramedics Cegedim companies in the field of physician software include Cegedim Logiciels Médicaux (with software branded CrossWay Ville, Médiclick, Médigest, Dia, dbmed, Ordogest), BKL Consultant (Doc Ware and Cardiolite), RMIngénierie (Logiciels +4000) in France, and In Practice Systems (Vision) in the United Kingdom, HDMP (Health One) in Belgium and Millennium (Millewin) in Italy. Cegedim is one of the leading European producers of medical and para-medical software with more than 100,000 workstations. The Group aims to strengthen this position and especially to be involved in the reforms undertaken by the State in both France and the United Kingdom. Cegedim Logiciels Médicaux / BKL Consultant / RMIngénierie in France In France, 2005 established CrossWay Ville as the market s benchmark for occupational software. Interest in CrossWay Ville has been strengthened by its capacity to respond perfectly to all regulatory requirements, to integrate DMP (Personal Medical File) compliance and medical networks goals, at the same time as satisfying the expectations of practitioners as much as possible. Integrated since March 2006, RMIngénierie designs a full range of medical and para-medical software for physiotherapists (n 1 in France), nurses, speech therapists, orthoptists, midwives, chiropodists, podiatrists and others. Cegedim stands now at the crossroad of a broad range of different healthcare practitioners which places the Group at the forefront of the Personal Medical File challenges, for which an experimental phase has already been launched. Furthermore, Cegedim is the uncontested leader in terms of the number of practitioners transmitting their electronic healthcare files and is at the forefront of secure communicative solutions between professionals. In Practice Systems / HDMP / Millennium, in the UK, in Belgium and in Italy In the United Kingdom, In Practice Systems is strengthening its leading position in the primary care sector with Vision. The reforms undertaken by the National Health Service have resulted in different levels of inter-operability between healthcare professionals, which are progressively met by In Practice Systems software, duly adapted for General Practitioners. Obvious synergies are also developing with software for pharmacies, which are also involved in the British reforms. The Cegedim Group has continued to extend its influence in Europe, again in March 2006 with a significant investment made in Millennium, the leading provider of medical software in Italy (more than 11,000 workstations). Intranet and healthcare portal Santesurf Santesurf is France s secured IT portal exclusively for professionals in the healthcare sector. Physicians can use the portal to transmit electronic healthcare files to primary health insurance providers regardless of whether they are equipped with Cegedim systems. Doctors also benefit from specialized services such as electronic mailboxes and Internet access. Santesurf is the only free and secure French intranet for healthcare professionals (doctors, pharmacists). 31,000 doctors use Santesurf.com every day and 9,000 use the electronic healthcare file transmission service. Santesurf is France s leading private pooling service with a market share of nearly 17%. Santesurf, a private operator, has become the benchmark information exchange platform for healthcare professionals and medical reps. Santesurf serves as a hub for the majority of the information flow managed by Cegedim. 21

23 Professional pharmaceutical database Banque Claude Bernard RESIP company RESIP (Recherches et Etudes en Systèmes Informatiques Professionnels) provides healthcare professionals with a scientific database to assist in prescribing and issuing drugs, the Banque Claude Bernard (BCB), the only electronic database to compete with Vidal. The BCB is integrated into pharmacy management software marketed by the Alliadis network (Alliance- Plus software) and by the Data Conseil network (Premium software), with more than 8,000 subscribing pharmacies. This database is also included in software for doctors: 10,000 practices are currently supplied. In the future the database will be implemented on an increasing number of physician workstations owned by the Cegedim Group in France and will also be distributed by other medical software suppliers. As the major tool of its kind on the web market, the BCB is designed for integration into healthcare gateways and sites. The BCB s technology makes it easy for hospitals to integrate the database into their Intranet systems for rapid consultation, and it also allows for interface with management software through specialized APIs (Application Program Interface). Currently over 150 hospitals have deployed the BCB on their Intranet systems. For the first time in 2006, hospitals will use the BCB integrated into the prescription or dispensation software. Rosenwald Rosenwald, which has specialized in the publication of healthcare professional directories for more than one hundred years, joined the Cegedim Group in April Rosenwald markets three historic directories, the doctors directory (which includes a geographic list of doctors by specialty), the pharmacists directory (listing pharmacists) and the private hospital s directory (which provides useful information on more than 7,800 private hospitals). Paper copies of these directories are available or they may be consulted online at Rosenwald.com. In 2006, Rosenwald has confirmed its role as the provider of promotional tools dedicated to the healthcare professionals, with the acquisition of Mail Group, the French leader in medical «bus-mailings» (allowing each advertiser to share the costs of their mailing operations). Scientific, medical and promotional information MedExact MedExact works in synergy with all Cegedim Group companies which are involved in promotion excluding medical reps. The «ScreenPub» service concerns doctors equipped with Cegedim medical software interconnected to the Cegedim server. It allows the exchange of information and in particular the downloading and circulation of advertising campaigns directly onto screens. Since 2002, the «MedExact medical promotional department» has placed relations with scientific companies and the creation of medical-scientific communications at the heart of its business. It uses its large network of experts and electronic communications (via its therapeutic information internet site medexact.fr and via ) to transmit medical 22

24 information to more than 65,000 general practitioners and specialists. MedExact also provides companies in the pharmaceutical sector with solutions for creating and formulating interactive messages to announce product launches, strengthen market positioning, promote brands and enhance public image. With its panel of 7,900 pharmacies computerized by Alliadis, «Pharmexact» offers the pharmaceutical sector all studies related to medical products or OTC and provides promotional loyalty tools and information communication tools for pharmacists. With its Internet-based panel of 600 representative pharmacies, PharmExact carries out ad-hoc studies into the prescription and issuing of medical products. These surveys allow information on medical prescriptions, the attitude of the pharmacy and can even collect the opinion of the patient. RNP RNP (Réseau National de Promotion) is the undisputed French benchmark for POS (Point of Sale) advertising in the pharmaceutical and para-pharmaceutical sectors. RNP promoters and merchandisers provide pharmaceutical firms with privileged access to 20,000 pharmacies in France on a three-weekly basis. Services include: Window dressing from standard to event-specific. Implementing in-store promotional materials (shelving, counters and displays). Conducting surveys. Personnel are equipped with PDAs which allow them to provide follow-up of the results of their work in real time, including digital photos. Pharmaceutical companies can access follow-up of their promotional activities via the RNP Internet site. 23

25 Healthcare insurance services Drawing most of its abilities from the production of professional software and the processing of complex information, the Cegedim Group offers (through its «Healthcare insurance services» sector), a large range of services dedicated to the main health insurance players. These players are at the interface with all healthcare professionals thanks to the Group s healthcare flow management systems, which are adapted to the increasing computerization requirements of the market. 24

26 IT for insurers Soltim-Proval Soltim-Proval, the Cegedim Group s software package and service center for the personal insurance sector, has a nationwide staff of 414. Leaders in the French market, Soltim-Proval s solutions cover 25 million people in France insured under the public and private health programs, providence programs and retirement programs, which generate 150 million EDI and direct payment exchanges per year. Soltim-Proval provides products for all market operators including insurance companies, providence funds and agents. In 2005 Soltim-Proval launched a new global healthcare flow management service based on additional high value-added services with Centre de Services accreditation through GIE SESAM-Vitale and acceptance of the first DREs (Electronic requests for reimbursement). Several significant projects, creating long-term client relationships are evidence of the commercial success of the services provided: implementation of a new information system for the Union Mutualiste Retraite in accordance with deadlines and agreements, the putting into production of a global applicative solution in ASP mode in partnership with Cegedim Logiciels Médicaux in order to manage Mutuelles de Provence treatment centers, the start-up of the Moroccan Social Security Offices information system (which will manage the health insurance program for private sector employees and civil servants), and the creation of a local «Cegedim Morocco» company. Soltim-Proval has developed in an environment facing ongoing restructuring with an inexorable concentration of insurers, which contributes to increasing outsourcing requirements. These challenges require a global approach to the market which has been perfectly integrated by Soltim-Proval, with its solutions ranging from the supply of information systems, all EDI tools (flows, DREs and others) to management outsourcing (third party payers, account management and others). Healthcare flows CETIP Tiers-Payant Santé-Pharma As the exclusive technical provider for the Santé- Pharma Association since 1991, CETIP is the French healthcare market leader in managing direct billing and payment flow. CETIP has processed more than 70 million billing and payment transactions in 2005, 99% of which were processed via remote transmission. The company manages nationwide direct payment by third-party payers for the accounts of 10 million beneficiaries, over 30,000 healthcare professionals and 200 health insurance companies. CETIP s in-depth knowledge of the healthcare market guarantees high quality services. 51,868 46,234 65,942 70,885 62,994 Thousands of direct billings processed by Cetip In 2005 CETIP extended the third-party direct payment system to physiotherapists, radiologists and medical analysis laboratories in collaboration with the Santé-Pharma Association, the Federation of French Insurance Companies and GIE SINTIA in its role as Private Health Insurers project manager. CETIP formed a partnership with Soltim-Proval to design the Cegedim Group s new generalized direct billing and payment solution. This system checks the validity of the status of the policy holder at the desk of the healthcare professionals before allowing any transaction for remote payment (i.e. before the reimbursement of the healthcare professional by the duly confirmed private health insurer). The same solutions can also be provided at the level of the health insurance company. 25

27 High performance, efficient management processes and a top-quality call center have made CETIP the preferred partner of public and private insurance companies and insurance agents. As a sign of its durability and experience, in 2006 CETIP will celebrate its 30th anniversary, its 15-year partnership with Santé-Pharma and its 10-year as a member of the Cegedim Group. Electronic data interchange Cegedim EDI For 15 years, Cegedim EDI has computerized all supply chain documents (order forms, dispatch notes, invoices and others). Using the Edipharm system, mainly between wholesale distributors and pharmaceutical firms, its activities rapidly spread to medical analysis laboratories and veterinary medicine purchasing centers and laboratories. A proven and well-positioned architecture, new Internet technologies, using XML and the development of new faster EDI protocols for the web have allowed Cegedim EDI to diversify into transport, mass distribution and administrative services with tax and social security on-line declaration services. In 2005, Cegedim EDI was an undisputed player in the computerization of invoices with more than 17 million flows processed and the launch of new «Global Invoice Services» tax-compliant computerization platform, which controls all functional, technical and legal aspects of invoice computerization, their storage and reproduction. In 2006, Cegedim EDI with the Edipharm system, will create and offer to convey pharmaceutical products traceability information. Hospit@lis Hospit@lis provides a gateway to optimize comprehensive supply management of medicines, medical devices and laboratory reagents between healthcare establishments and their suppliers. Hospit@lis service covers all exchanges from invitations to tender to orders and their associated logistical information and invoices. Furthermore, Hospit@lis places an exhaustive medicines database (BCB Banque Claude Bernard) at the disposal of healthcare practitioners working at the hospital, through its Internet gateway. The «Hospi-marchés» module allows all public organizations to computerize their invitations to tender, to receive and process the responses of suppliers securely and in accordance with Article 56 of the Public Markets Code. Hospit@lis improves the traceability of exchanges by centralizing all the information regarding the signing of orders and their monitoring on its Internet gateway. The purchase and integration of the APSYS-NET gateway in 2005 has strengthened the Hospit@lis service in terms of the number of healthcare establishments as well as medical device providers connected to its gateway. In order to expand, Hospit@lis has also formed strategic partnerships with other market players such as GHX Europe, for whom it processes part of the orders for medical devices. Hospit@lis is now present in more than 300 major healthcare establishments, including 17 University hospitals, and transmitted more than 240,000 orders in ASPOne.fr ASPOne.fr is a gateway that allows businesses, accounting firms and certified tax preparers to file returns and forms online. A unique, fully securitized solution, ASPOne.fr enables electronic transmission of all tax returns, tax forms, VAT forms and other government forms. Users benefit from standardized monitoring, a single interface and a single intermediary for all types of returns and forms. For subscribers, the gateway takes charge of all technical and regulatory developments and is constantly enhanced by new services to give the needs of declarants the best response. Thus, the recent opening of an on-line VAT capture service called WEB- TVA allows companies to meet the new on-line declaration legal obligations imposed by the 2006 Finances Act. ASPOne.fr is marketed either directly in the form of an annual subscription or under the client s brand (e.g.: as Crédit Lyonnais TéléTransEDI gateway). 26

28 Today more than 1,800 clients in France (representing more than 50,000 companies and 750 accounting firms) have placed their trust in the ASPOne.fr gateway, and made Cegedim the benchmark company for computerized exchanges outside the healthcare sector. The electronic transmission of treatment forms is a service provided in addition to the software and databases supplied by the Group. This service offers a permanent solution to facilitate day-to-day contacts with healthcare professionals. Déclaratis Déclaratis is the Cegedim subsidiary responsible for developing the partnership with the Sage group in order to develop computerized exchanges of the publisher s client database (500,000 accounts). The Sage DirectDeclaration tax and social security online declarations service uses the computerized exchanges platform operated by Cegedim within the framework of this partnership. The solutions implemented are distinguished by the very strong integration in Sage management software and their great ease of deployment. Electronic transmission of treatment forms Qualitrans-Télépharma As a Technical Pooling Organization, Qualitrans- Télépharma is responsible for the secure electronic transmission of treatment forms between healthcare professionals (pharmacists, doctors, biologists, radiologists and others) and paying organizations by integrating the various SESAM-Vitale system norms. Qualitrans-Télépharma allows the real time management and specific monitoring of dispatch notes (FSE, DRE and others) via the secure Santesurf Intranet: acknowledgments of receipt, rejected invoices, journal of payments by batch and others. It also offers access to more than 6,000 organizations paying for public and private schemes in France and in Overseas Departments and Territories. Qualitrans-Télépharma managed more than 65 million flows in 2005, 20% more than in This expansion should continue in 2006 with the deployment of the service to new categories of healthcare professionals and the launch of new high value-added services. 27

29 Technologies and services With long and in-depth experience in database management and the design of value-added services, the Cegedim Group aims to provide optimum support to its clients in mastering, managing and fully benefiting from customer information. The pursuit of these objectives has allowed the Group to develop niche abilities in terms of technologies and services. The expansion of Cegedim s customer base beyond the healthcare market is evidence of the dynamism of these activities. 28

30 Technologies A specialist in computerized management systems, the Cegedim Group has enriched its offerings in a variety of fields: The capture, management and circulation of information. Outsourcing services. Outsourced human resources management. Internet services and hosting. Leasing. The capture, management and circulation of information Docubase Systems Since 1989, Docubase Systems has published and integrated its own solutions in the GEIDE field (electronic management of information and documents for companies). The Docubase Information Suite TM service covers all aspects of document and information computerization, whatever their original nature and medium. The process starts with the capture of the information by digitization, recognition or automatic reading of documents, importation of office documents, s or customized files and provides secure filing, combined with various stages enabling the classification, control, validation, circulation and management of documents. The service consists of software components and toolboxes. This modular nature allows it to meet standard and specific requirements in a professional environment. All of these modules allow a full information processing solution to be created. Along with publishing solutions, in late 2004 Docubase Systems began providing a range of outsourced services, with a team in charge of document digitization and entry, that can be provided on a recurring basis or for one shot acquisition of archives. Docubase has had a subsidiary in the United States since 1997 in order to develop its network of partners and authorized dealers, which also helps keeping a keen eye in new developments in the market. Its network of 50 partners in France and abroad has allowed it to be as close as possible to its clients and to cover numerous vertical markets. Outsourcing services PCO Cegedim Prestation Conseil Outsourcing PCO Cegedim provides information management services and solutions that enable companies to secure, administer and supervise the various components of their systems in a simplified, integrated and centralized manner. PCO Cegedim specializes in adding value to the information systems of major companies, government agencies, local government organizations and teaching or research institutes. PCO Cegedim s product range focuses on 2 main areas: The management of the information system using ITIL best practices. The integration of administration and security solutions for the system and network. PCO Cegedim, in association with partners in publishing and manufacturing, provides solutions especially designed to meet the evolving needs of the market. 29

31 Outsourced human resources management Cegedim SRH The benchmark company in France and in Europe for outsourced payroll and human resources management, Cegedim SRH now has more than 550 clients, including certain of the most famous names in industrial and service sectors. Thanks to Mercure Horizon, Cegedim SRH s complete, modular information system, the company has the capacity to offer a wide range of services: Mercure Payroll and Personnel Administration: Payroll management, personnel administration, time and activities management, company benefits management, badging solutions. Mercure Pilotage: Wage management, social and HR report, workforce management, retirement compensation. Mercure RH: Performance evaluation, succession and career planning, hiring management, job and skills planning management, job management and organization, training management, analyses and reports. Mercure ERM and management of employee relations: vacations and absences, employee selfservice, management self-service, time sheet management, employee activity report by project, expense report entry, training requests. fully dedicated to high-availability applications, Cegedim has a secure platform, ultra-rapid Internet access and connection to strategic occupational databases. Cegedim has special expertise in the fields of managing and enhancing electronic information flows. Cegedim particularly hosts the Hospit@lis and Diagdirect e-procurement gateways, the CIP gateway and its exhaustive on-line products. Midiway Midiway specializes in IT engineering and interactive communications. Recognized experience in developing and implementing complex projects and expertise in information management technology make Midway an invaluable partner: Implementation of management applications with a high proportion of specialized components. Web project development (Internet, Intranet, Extranet). Leasing Cegelease Cegelease, marketed under the brand names Cofidata and Pharmalease, is a leasing company providing financing packages for pharmacies. Mercure GED: document server and electronic employee file. Cegedim SRH has experienced healthy volume growth and the outlook for continued expansion is strongly positive. Internet services and hosting Cegedim Cegedim has confirmed its presence in hosting Internet application as a result of its proven network and technical infrastructure. From simple Internet access on a shared server to personalized solutions 30

32 Services Cegedim has drawn on its database expertise to develop professional address lists for business-to-business communications. As customers have shown a preference for entrusting their promotional campaigns to a single supplier, Cegedim has expanded its activities to cover the entire direct marketing chain. Corporate databases, CRM and associated services Cegedim Communication Directe (CCD) Cegedim Communication Directe designs, manages and markets a wide range of databases, and is the premier supplier of business address lists in France. CCD provides valuable data for business-to-business communications and, from the acquisition stage to the supply stage, data is updated and refined through input from an extended range of services. 31

33 Data supply Corporate and managerial databases: 369,000 companies classified by revenue, with telephone and fax numbers, and over 604,000 decision-makers organized by position and skill areas. CEO databases: 2,766,000 corporate headquarters including names of top managers (President and CEO, GM, Manager) and one-person businesses with telephone and fax. INSEE Sirène database (official distributor since 1981): 4,700,000 companies (comprehensive directory). Sector databases: independent professionals (such as doctors, attorneys and others), government agencies, elected representative, hotels, restaurants and senior citizen associations. French and European healthcare databases. Data processing (corporate and personal) Normalization, restructuring, clearing. Merge and purge, reconciliation, data consolidation. Services for company databases Database auditing. Verification. Data enhancement. Maintenance of customer data using CCD proprietary update techniques. Data analysis, client profiles. B to B segmentation, marketing affinity scoring: a scoring model that uses financial information to optimize B-to-B segmentation for the most effective client prospecting. CCD benefits from specialized programs and tools, a number of which are unique on the French market, such as the SOURCE database, a log of all changes in French company registration numbers since Subscription management SIGA: all-purpose professional software package for managing subscriptions and client information (press and home shopping). Comprehensive, integrated direct marketing services CCD offers comprehensive direct marketing services that include every process in the direct marketing chain via specialist subsidiaries (design, printing, routing, enveloping). Cegedim Marketing Process (CMP) Cegedim Marketing Process specializes in the design of complex applications for producing recurring publications such as management and transaction documents and high-volume direct marketing campaigns. CMP ensures all back-office aspects of client relations (from hard copy documents to electronic documents) as well as complete project planning for direct marketing operations and document management logistics for major service providers and finance companies. CMP s expertise and efficiency is the result of the company s vast experiences in document design, digital printing, electronic document organization and management of new communications media. Electronic publishing / insertingfolding / logistics / routing SDI SDI is an ISO 9001 V2000 integrated, automated largescale document production center. SDI offers traditional publishing services as well as services based on new technology such as storing, hosting, monitoring and production control. Located on a site with potential for expansion, SDI s 15,000 m 2 plant is equipped with a complete park of continuous and page-by-page laser printers, blackand-white or color, as well as OMR-BCR-OCR document scanning and envelope stuffing equipment. Thanks to SDI s IT infrastructure, the company has developed desktop publishing facilities and largescale direct marketing services as well. SDI also provides partial or complete production and enveloping for large firms that wish to continue to outsource administrative documents (invoices, bank statements, pay slips) or marketing communications (brochures, letters). 32

34 Médipost Located on an 8,500 m 2 site, Médipost has full mail processing skills and particularly specializes in direct marketing. Médipost provides large advertisers with IT services, continual or page to page customization, off or on-line finishing, the enveloping and sealing, sorting and mailing of their written communication industrial operations. Equipped with the latest generation tools, Médipost has carried out complex operations which have ensured the success of its partners in their advertising campaigns. Printing Pharmapost Pharmapost, an ISO 9001 certified company, is a mass production printing company specializing in fine paper printing and finishing. In 2005 Pharmapost produced 400 million pharmaceutical product notices, flat, folded or rolled, which places the company among the French leaders on this segment. Sample management Tracere 3S Pharmastock Pharmaceutical firms require sample management systems that meet stringent regulations governing traceability and distribution. The Cegedim Group combines expertise in healthcare and in file management to provide two sample management packages: Tracere, designed to respond to the sample management needs of medical reps and doctors. 3S designed to manage sample requests from healthcare professionals. Sample management packages are supported by Pharmastock logistics. Pharmastock is a certified pharmaceutical products distributor. 33

35 International operations Cegedim operates in over 60 countries Turnover > 50 M from10 to 50 M from 2.5 to 10 M < 2.5 M 34

36 35

37 Management and human resources Board of directors Since Position Jean-Claude Labrune 1/12/1969 Founder, Chairman and Managing Director Financière Cegedim 1/04/1984 Holding company SAS represented by Pierre Marucchi GERS 6/03/1995 Economic interest grouping of GIE represented by François Blanot pharmaceutical companies based in France Alliance Santé Distribution 22/12/2000 Company owned by Alliance Unichem SA represented by Jean-Louis Mery (pharmaceutical distributor) Laurent Labrune 18/04/2001 Chairman and Managing Director of Cegedim SRH Human resources The total workforce of the Cegedim Group comprised 4,696 employees as at 31 December 2005, representing an increase of 12% over the previous year. The workforce increased by 369 employees, not including acquisitions, which reflects the continuation of an active recruitment policy. The intention is to train young graduates in the skills needed to pursue a career at Cegedim and to attract experienced staff who will contribute their knowhow to the Group. Apart from technical skills and a good knowledge of customers' businesses, the selection criteria applied by Cegedim involve the sharing of values such as innovativeness, pragmatism and the idea of service. The working conditions, a steady remuneration policy and the opportunities for career development resulting from growth explain why staff turnover is low in comparison with that seen in the same areas of activity. Finally, to assist in the development of skills in line with its range of services, the Cegedim Group has this year once again invested substantially in staff training. These factors are the main guarantees of the continuity and quality of service provided by the Group to its customers. Cegedim Group workforce evolution Healthcare and strategic data Technologies and services Total 4,180 4, cegedim au cœur de la

38 Company management General management CEO : Jean-Claude LABRUNE Managing Director : Pierre MARUCCHI Operational management Healthcare and strategic data CRM and strategic data Jean-Paul ROQUES Healthcare professionals Jean-Paul ROQUES Healthcare insurance services Pierre MARUCCHI CRM Strategic data Healthcare development Robert GRANDI CRM - CRM ONEKEY CRM ATLAS GET Sales force optimization Auditing, business intelligence and ROI Prescription analysis, business intelligence, point of prescription promotion Health economy Sales data - UK Software for pharmacists - France Software for doctors - France Software for doctors and pharmacists - UK Promotional information IT for insurers Payment flow and information flow Electronic data interchange/ Electronic treatment forms Karl GUENAULT Jeremy MACKLIN Angela MICCOLI Thierry DELCOUR Philippe HAMON Guillaume ROUSSEL Yann GOURMELEN Pierre CAGET Bruno SARFATI Jean-Louis LOMPRÉ Philippe LE JEUNNE Jean-Louis LOMPRÉ Christian ARMANDO Jean-Paul ROQUES Max BRIGHTON Marie-Hélène BONNAUD Antoine AIZPURU Patrick COHEN Laurent MARYSSE Laurent MARYSSE Technologies and services Technologies Pierre MARUCCHI Services Daniel FLIS External management of human resources External provision of IT services Electronic document management Internet, Web-EDI, e-crm Financial leasing RYSSE Business address lists and allied services Publishing, electronic publishing and printing Tam DOMINH Envelope stuffing and routing Medical samples management Laurent LABRUNE Claude GARCÈS Yannick TABANON Laurent MARYSSE Philippe STORET Didier DESENFANS Jean-Marc POMMERET Didier BARBIER Tam DOMINH Philippe VERET décision 37

39 Consolidated accounts Consolidated profit and loss account (in million euros) IFRS accounting standards 31/12/2005 % of turnover 31/12/2004 % of turnover Turnover France Turnover outside France Turnover % % Purchasing External costs Personnel costs Provision, amortization and depreciation charges Other operating income (+) and charges (-) 1-7 Operating income (EBIT) % % Financial income 5 6 Cost of financial indebtedness Net financial costs % 0 0 % Corporation tax Share of profits in affiliate undertakings Net consolidated income % % Group share % % Minority interests Net consolidated income per share ( )

40 Consolidated balance sheet (in million euros) IFRS accounting standards 31/12/ /12/2004 Evolution ASSETS Acquisition goodwill % Other fixed assets % Trade debtors > 1 year % Other non-current assets % Trade debtors < 1 year % Cash at bank % Other current assets % Total % SHAREHOLDERS' EQUITY AND LIABILITIES 31/12/ /12/2004 Evolution Shareholders' funds attributable to the Group % Minority interests % Shareholders' funds % Financial debt > 1 year % Other non-current liabilities % Financial debt < 1 year % Trade creditors % Taxation and social security % Other current liabilities % Total % 39

41 Stockmarket performance Cegedim has been listed on the Paris Second Market since April 1995, and is now listed on Eurolist by Euronext Paris, compartment B. On 31 December 2005, the share price is 73 and the market capitalization is 681 million. The share price has been multiplied by 7.5 since April Evolution of share price /05/95 01/01/96 01/01/97 01/01/98 01/01/99 01/01/00 01/01/01 01/01/02 01/01/03 01/01/04 01/01/05 15/03/06 Cegedim share Code ISIN FR Code Reuters CGDM.PA Code Bloomberg CGM Investor information Sandrine Debroise Chef Financial Officer Tel : + 33 (0) Simon-Laurent Zaks Investors Relations Deputy Manager Tel.: + 33 (0) Fax: + 33 (0) [email protected] 40

42 General share information Number of issued shares 9,331,449 9,331,449 Floated as at 31 Dec. (% of total) 20 % 20 % Face value (euros) Price as at 31 Dec. (euros) Market capitalization (million euros) Data per share (euros) Net income attributable to the Group Gross dividend Shareholders fund attributable to the Group Some financial analysts monitoring the company ODDO MIDCAP EXANE BNP PARIBAS CIC SECURITIES SOCIETE GENERALE CREDIT AGRICOLE INDOSUEZ CHEUVREUX IXIS MIDCAPS ARKEON FINANCE Julie AGNES Jean-Pascal BRIVADY François HAMON Patrick JOUSSEAUME Axelle MESLAY Stéphane NIERES-TAVERNIER Grégory RAMIREZ 41

43 Contacts FRANCE Boulogne-Billancourt APSYS NET ASPONE.FR CEGEDIM SA CEGEDIM Communication Directe CEGEDIM Marketing Process CEGEDIM EDI CEGEDIM Logiciels Médicaux CEGEDIM SRH CEGERS CETIP COFIDATA DECLARATIS DOCUBASE Systems EDIPHARM HOSPITALIS ICOMED ITOPS MEDEXACT PHARMA CRM Division QUALITRANS / TELEPHARMA RNP SANTESURF Services TVF 127 à 137, rue d'aguesseau Boulogne-Billancourt Cedex Tel.: + 33 (0) Fax: + 33 (0) CAM / DR / BKL-THALES FRANCE 90/92 Route de la Reine Boulogne-Billancourt Cedex Tel.: Fax: ROSENWALD 104 Rue d'aguesseau Boulogne-Billancourt Cedex Tel.: + 33 (0) Fax: + 33 (0) Boulogne-sur-mer RESIP 56, rue Ferdinand Buisson Boulogne-sur-mer Tel.: + 33 (0) Fax: + 33 (0) Lille Immeuble Guilaur Rue de la Zamin Capinghem CEGELEASE Tel.: + 33 (0) Fax: + 33 (0) QUALIPHARMA Tel.: + 33 (0) Fax: + 33 (0) Longjumeau SDI ZI La Vigne aux Loups, 4, rue George Sand Longjumeau Tel.: + 33 (0) Fax: + 33 (0) Lyon Immeuble le Discover 82-84, Bld Vivier-Merle Lyon Cedex 03 CEGEDIM SRH Tel.: + 33 (0) Fax: + 33 (0) DOCUBASE SYSTEMS Tel.: + 33 (0) Fax: + 33 (0) MEDLINE 13 cours de Verdun LYON Tel.: + 33 (0) Fax: + 33 (0) SOLTIM-PROVAL 22 rue Camille Roy Lyon Cedex 07 Tel.: + 33 (0) Fax: + 33 (0) SOLTIM-PROVAL Le Britannia C 20 Bld Eugène DERUELLE LYON Tel.: + 33 (0) Fax: + 33 (0) Marseille SOLTIM-PROVAL Le Grand Prado - Bât. B 20 allée Turcat Méry Marseille Cédex 08 Tel.: + 33 (0) Fax: + 33 (0) Montargis 326, rue du Gros Moulin Amilly Montargis Cedex AMIX Tel.: + 33 (0) Fax: + 33 (0) PHARMASTOCK Tel.: + 33 (0) Fax: + 33 (0) MEDIPOST Impasse des Fleurs Amilly Montargis Cedex Tel.: + 33 (0) Fax: + 33 (0) PHARMAPOST 573, avenue d'antibes Amilly Montargis Cedex Tel.: + 33 (0) Fax: + 33 (0) Nanterre DATA CONSEIL 52, rue Jean-Jacques ROUSSEAU Nanterre Tel.: + 33 (0) Fax: + 33 (0) Nice ALLIADIS ALLIANCE SOFTWARE Crystal Palace Promenade des anglais Nice Tel.: + 33 (0) Fax: + 33 (0) Paris SOLTIM-PROVAL SELECTIS CONSULTING 8, rue d Athènes Paris Tel.: + 33 (0) Fax: + 33 (0) Rodez RM INGÉNIERIE Avenue de la Gineste RODEZ Tel.: + 33 (0) Fax: + 33 (0) Toulouse MIDIWAY Miniparc Bâtiment 1 BP 256 Rue de la découverte Labège Innopole Tel.: + 33 (0) Fax: + 33 (0) SOLTIM-PROVAL Labège Innopole Rue Marco Polo BP Labège Cedex Tel.: + 33 (0) Fax: + 33 (0) Vélizy PCO CEGEDIM 15, rue Paul Dautier Vélizy Tel.: + 33 (0) Fax: + 33 (0) ALGERIA CEGEDIM ALGERIE 12 boulevard Saïd Hamdine Hydra, Alger Tel.: Fax: ARGENTINA CAM / DR ARGENTINA Cervino 4407/17 5 Piso " A " C1425AHB Buenos Aires - Capital Federal (1425) Tel.: Fax: AUSTRALIA CAM / DR AUSTRALIA AND MALAYSIA Level 2, 5 Queen St Chippendale NSW 2008 Tel.: Fax: AUSTRIA CEGEDIM GmbH Am Heumarkt 10 A 1030 Wien Tel.: + 43 (0) Fax: BELGIUM Avenue de Roodebeek, Bruxelles HDMP Tel.: Fax: CAM / DR / BKL BELGIUM, NETHERLANDS AND LUXEMBURG Tel.: Fax: CEGEDIM BELGIUM sa ICOMED BELGIUM 138, chaussée de Charleroi 1060 Bruxelles Tel.: Fax: BRAZIL Rua Dr Cardoso de Melo # 900 2o andar VILA OLÍMPIA, SÃO PAULO, SP.Cep CEGEDIM DO BRASIL Ltda. Tel.: Fax: CAM / DR BRAZIL Office Tel.: Fax:

44 CANADA GERMANY ITALIA NORWAY CAM / DR CANADA 8250 boul Decarie, bureau 340 Montreal (Quebec) H4P 2P5 Tel.: Fax: CHINA CAM / DR CHINA Room 2301, Golden Magnolia Plaza 1 Da Pu Road Shanghai Tel.: Fax: COLOMBIA CEGEDIM COLOMBIA, Ltda. Carrera 12 N Ofna. 501 Sante Fe de Bogotá Tel.: Fax: CZECH REPUBLIC CEGEDIM CZ s.r.o CAM / DR CZECH REPUBLIC Office Zbuzkova 47/ Praha 9 - Visocany Tel.: Fax: CEI STATISTICS, s.r.o Sumavska 519/ Brno Tel.: Fax: DENMARK CEGEDIM DENMARK a/s Stationsparken 37 DK-2600 Glostrup Tel.: Fax: EGYPT TRENDS TECHNOLOGY Ltd 88 Makram Ebeid, Borg El Yasmine Nasr City, Cairo Tel.: Fax: ECUADOR CEGEDIM ECUADOR, s.a. Edif. Axios Ofna 708 Av. Shyris N e Isla Floreana Quito Tel.: Fax: Zeppelinstrasse 2-4, Bensheim, CEGEDIM Gmbh MEDIMED GmbH EASYCOM Tel.: Fax: CAM / DR / BKL Tel.: Fax: CAM / DR / BKL GERMANY, AUSTRIA AND SWITZERLAND Neumarkter Str. 81 D München Tel.: Fax: GREECE CEGEDIM HELLAS CAM / DR GREECE Office Ethrio Center Agiou Konstantinou 40 off Maroussi, Athenes Tel.: Fax: GUATEMALA CEGEDIM CENTRO AMERICA Y EL CARIBE, s.a. 2a. Calle Apto. 3A Edif. Ferrol Vista Hermosa 1 Zona 15 Guatemala CA Tel.: Fax: HUNGARY CEGEDIM MAGYARORSZÁG Kft CAM / DR HUNGARY Office Krisztina Plaza - Budapest I Krisztina Krt. 39/b. II. em. - H-1013 Tel.: Fax: INDIA CEGEDIM INDIA Kamlesh Punjabi Ashok Nagar,F/301, Vazira Naka, Borivali[West] Mumbai Tel.: IRELAND CAM / DR IRELAND 26/27 Upper Pembroke Street Dublin 2 Tel.: Fax: CEGEDIM ITALIA s.r.l. Via Valtellina, Milano Tel.: Fax: CAM / DR / BKL ITALY Viale Marche Milano Tel.: Fax: JAPAN CAM / DR JAPAN 4F Yodoyabashi Toda Bldg Fushimi-machi, Chuo-ku Osaka, Japan Tel.: Fax: MAROCCO CEGEDIM MAROC CAM / DR MOROCCO Office 219, Boulevard Mohamed Zerktouni, Angle Brahim Roudani 6 étage n Casablanca Tel.: Fax: MEXICO Priv. Cuauhtémoc No. 2B Col. Tizapán San Angel, Mexico, D.F. CEGEDIM MEXICO,s.a. DE C.V. Tel.: Fax: CAM / DR MEXICO Tel.: Fax: NETHERLANDS CEGEDIM BV De Molen DB Houten Tel.: Fax: NEW ZEALAND CAM / DR NEW ZEALAND Office PO Box Milford Auckland Tel.: Fax: CEGEDIM NORWAY as Visit address: Stubberudveien 8, N-0668 Oslo Post address: Post box 6 Leirdal, N-1008 Oslo Tel.: Fax: POLAND Ul. Pileckiego Warszawa CEGEDIM SP z.o.o Tel.: Fax: CAM / DR POLAND Tel.: Fax: PORTUGAL CEGEDIM PORTUGAL Avenida Infante Santo, 43 3 Edifício Infante Santo Lisboa Tel.: Fax: CAM / DR PORTUGAL Av Almirante Reis, 113, 5. -Esc Lisboa Tel.: Fax: ROMANIA CEGEDIM ROMANIA s.r.l. CAM / DR ROMANIA Office Str Dornei nr. 81 Sector Bucharest Tel.: Fax: RUSSIA CEGEDIM RU Bakhrushina Street 15 Building Moscow Tel.: Fax: SLOVAKIA Zelinárska Bratislava CEGEDIM SK Tel.: Fax: CAM / DR SLOVAKIA Office Tel.:

45 SOUTH KOREA CAM / DR KOREA #605 Namsong Building Itaewon-dong, Yongsan-gu, Seoul Tel.: Fax: SPAIN Albasanz 15, Planta 4, Edificio B Madrid CEGEDIM HISPANIA, s.a Tel.: Fax: CAM / DR SPAIN Tel.: Fax: CEGEDIM HISPANIA, s.a Torre Mapfre Calle de la Marina, 16-18, 10 D Barcelona Tel.: Fax: SWEDEN CEGEDIM SWEDEN ab Norgegatan 1, Box 1091, Kista, Tel.: + 46 (8) Fax: + 46 (8) CAM / DR NORDIC Office (DENMARK, NORWAY, SWEDEN, FINLAND) Grindvägen 2 SE Kullavik Tel.: SWITZERLAND CEGEDIM SRH s.a. Albisriederstrasse 80 CH Zürich Tel.: + 41 (0) Fax: +41 (0) CEGEDIM SRH 48, route de Chancy Case postale Petit-Lancy 2, Genève Tel.: Fax: TUNISIA CEGEDIM TUNISIA sarl Immeuble Fajr Rue du lac Lochness - Apt Berges du Lac Tunis Tel.: Fax: TURKEY CEGEDIM A.S. CAM / DR TURKEY Office Dikilitas, Yenidogan Sokak Yildiz Is Merkezi N 1 Kat : Besiktas Istanbul Tel.: Fax: U.K. COMPUFILE Ltd CAM / DR / BKL UK 1 Tannery House Tannery Lane Send Surrey GU23 7EF Tel.: Fax: EPIC DATABASE RESEARCH COMPANY Ltd Regeneration House, York Way King's Cross London N1 0UZ Tel.: Fax: IN PRACTICE SYSTEMS Ltd The Bread Factory 1A, Broughton Street London SW8 3 QJ Tel.: Fax: CEGEDIM Ltd CEGEDIM SRH Ltd 4th floor, Nicholsons House, Nicholsons Walk-Maidenhead Berkshire SL6 1LD Tel.: Fax: INFOPHARM Ltd INFOPHARM SERVICES INFOSANTE 3rd floor, Nicholson House, Nicholson Walk, Maidenhead, Berkshire SL6 1LD Tel.: Fax: ENIGMA HEALTH Coveham house, Downside bridge road Cobham KT11 3EP Tel.: CEGEDIM RX Cegedim House Marathon place Leyland PR26 7 QN Tel.: USA DOCUBASE SYSTEMS, Inc Mc Cormick Drive Suite 102 Clearwater, Florida Tel.: Fax: CEGEDIM USA, Inc. TARGET SOFTWARE, Inc. CEGEDIM ONEKEY, Inc South Cedar Crest Blvd. Allentown, PA Tel.: Fax: CAM / DR USA AND PUERTO-RICO 580 Sylvan Avenue Englewood Cliffs, New Jersey Tel.: Fax:

46 CE10/837 Public company with share capital of 8,891, euros Corporate head office: rue d Aguesseau, Boulogne-Billancourt - France Trade and Commercial register: Nanterre B Code NAF: 723 Z Phone: + 33 (0) Fax: + 33 (0) [email protected] Legal documents relating to Cegedim may be consulted at the company s head office.