Kernmodul Physiologie SS 2014

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1 Kernmodul Physiologie 2014 The present module intends to provide a deeper understanding of physiology, ranging from molecular and cell physiology to integrative human physiology. You will be exposed to present research areas in physiology at Charité and improve your scientific knowledge and research skills including data collection, analyses, interpretation, and discussing peerreviewed international publications. In addition to real data collections to be performed in class and complementing the lectures and seminars, the goals of the module will cover very accessible topics that include, but are not limited to basics of biosignal recording, processing, and analyses (e.g. filtering, artifact correction, smoothing, mobile monitoring technologies, validation of new technologies, etc.), chronobiology, brain function (EEG), physical activity, body composition technologies, electrophysiological techniques in epithelial physiology, optical methods (confocal laser scanning microscopy, super resultion microscopy, freeze fracture electron microscopy), homology modelling of protein structure. This framework of topics will be delivered by close collaboration between the Institut für klinische Physiologie, CBF and Institut für Physiologie,, each covering their respective expertise in physiological research. On the following pages you will get some detailed information on class requirements, dates and times. We are looking forward to an exciting class and to welcoming you soon! Dr. Andreas Zakrzewicz Institut für Physiologie, PD Dr. Dorothee Günzel Institut für klinische Physiologie, CBF

2 Please note: (1) Max Number of tudents The class is limited to a max. of 10 students. You can sign up for the class via the Campus Management ystem. Please make sure that you sign up for all three classes, i.e. CUB820, CUB820a, and CUB820b Here is a link to the course catalog: and to our website: hould you have any further questions on registering, please get in touch with our teaching secretary Mrs. Cornelia Marruhn ( cornelia.marruhn@charite.de). (2) uccessful completion of module In addition to regular attendance you will have to pass an oral exam of about 20 min at the end of the term. The result of this exam will mainly determine your final mark. However, it is also a prerequisite of this module to deliver presentations to the class. You will be asked to give two presentations of approx. 20 min plus 10 min discussion. You will also chair sessions (lead the discussion). You will get credit for these presentations and they will be considered as part of your final mark! (3) Dates and times Typically, the lectures and seminars are held on Thursdays, h to h, and h to h, respectively. The class termed Übung is scheduled as a block and will be given 4 times on Mondays, h. Due to holidays some classes may be swopped.

3 (4) Dates and times Very importantly, please also check the exact location for each class. The first half of the semester (until June 5) will be conducted at Charite Universitätsmedizin Berlin, Campus Mitte. Depending on the type of class different rooms might have been booked. The second half of the semester (until July 17) will be conducted at Charite Universitätsmedizin Berlin, Campus Benjamin Franklin. Please note that due to the holidays in this semester, one Übung has been swopped with the lecture/seminar. (5) First and final class The module will start with an introduction and seminar on April 14. The final class will be your oral exam on July 17. (6) Language The module will be taught in English or German, depending on students preference.

4 Table 1. Overview of Term Date Time Place Type Topic April 14 April 17 April 17 April 21, April 24 April 24 April 28 May 1, May 5 May 8 May 8 May 12 May 15 May 15, May 19 May 22 May 22 May 26 CBF KR ehem. Apotheke KR ehem. Apotheke chröder-h chröder-h Introduction Preparing a cientific Presentation Zakrzewicz Physiology of red blood cells Referat: The meaning of red blood cell indices Referat: Anemia causes and diagnostics Referat: Hemoglobin and oxygen transport Referat: Compensation mechanisms of anemia Anm.: Weil es sich um den ersten Termin handelt, werden die Referatsthemen in der Gruppe bearbeitet. Habazettl Messtheorie (wie kommt der Wert zustande?), Probleme mit ignalen (Verstärkung, Rauschen, Filter, ROC etc.), Beispiele aus Physiologie und Klinik Habazettl Übung Entfällt wegen Übung Zakrzewicz Praktische Übungen zum Themengebiet Blut Miller-H Miller-H Microcirculation Übung Entfällt wegen R R Chronobiologie Übung Entfällt wegen R R Leistungsphysiologie und neurovegetative Regulation Übung Entfällt wegen

5 May 29 June 2 June 5 June 5, June 9 June 12 June 12 June 16 June 16 June 19 June 19 June 26 June 26 Monday June 30 July 3 July 3 Monday July 7 July 10 July 10 July 17 12:00 Übung Praktische Übungen zum Themengebiet NVR R R Extreme Umwelten CBF Introduction to Epithelial Physiology CBF Optical methods I Flow Cytometry, Confocal Laser canning Microscopy CBF Electrophysiology I, Ussing chamber CBF Electrophysiology II Epithelial Impedancepectroscopy CBF Optical methods II: uper Resolution Microscopy, Freeze Fracture electron microscopy, Microfluorimetry CBF Übung Group 1: Impedance spectroscopy Group 2: Confocal Laser canning Microscopy CBF Homology Modelling CBF Übung Group 2: Impedance spectroscopy Group 1: Confocal Laser canning Microscopy Oral Exam 20 min oral exam

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