Ministero della Salute

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1 Ministero della Salute Direzione Generale Ricerca Sanitaria e Biomedica e della Vigilanza sugli Enti BANDO 2010 RICERCA FINALIZZATA Elenco Progetti Cofinanziati dall'industria Presentati Calcium handling proteins common gene variants for the prediction of life threatening arrhythmias in ICD recipients with heart failure NEUROMED FRANCIA PIETRO BIO Cardiovascular and Electrical Signaling, Ion Transport, and Arrhythmias ESTA CERVICAL PLETHYSMOGRAPHY: A NEW TOOL FOR NON INVASIVE ASSESSMENT OF CEREBRAL VENOUS RETURN, AND A POSSIBLE SCREENING DEVICE FOR CHRONIC CEREBROSPINAL VENOUS INSUFFICIENCY Emilia Romagna Menegatti Erica CLI Vascular and Hematology Hypertension and Microcirculation HM Intensive nutritional counseling in cancer patients undergoing radiotherapy: a randomized controlled trial. SAN MATTEO Caccialanza Riccardo CLI Oncology 2 Translational Oncology Study and control of anticipatory movements followed to adaptation of sequential learned motorial gestures related to subjects intensively trained: FMRI and DTMRI study NEUROLESI Milardi Demetrio BIO Integrative, Functional, and Cognitive Sensorimotor Integration SMI InTeReSt Project. Integrated Tecnological Rehabilitation of Stroke. Upper limb rehabilitation: efficacy of robot versus neuromodulation treatment and assessment of adaptive central peripheral plasticity DON GNOCCHI Aprile Irene CLI Emerging Technologies and Training in s Brain Disorders and Related s Fellowship F DOSE WARPING METHODS FOR IGRT AND ADAPTIVE RT: DOSE ACCUMULATION BASED ON ORGAN MOTION AND ANATOMICAL VARIATIONS OF THE PATIENTS DURING RADIATION THERAPY TREATMENTS Emilia Romagna GUIDI GABRIELE BIO Oncology 2 Translational Radiation Therapeutics and Biology RTB Pagina 1 di 6

2 IMMUNOLOGICAL IMPACT OF SILIBININ TREATMENT FOR HCV RECURRENCE IN STABLE LIVER TRANSPLANTED PATIENTS Puglia Castellaneta Antonino CLI Immunology Immunity and Host Defense IHD Cancer biomarker detection using microstructured/super hydrophobic surfaces and advanced spectroscopy techniques Calabria Gentile Francesco BIO Bioengineering Sciences and Technologies Nanotechnology NANO Comparison of next generation sequencing based identification of translocations with copy number alteration based identification of deletions for the development of patient/tumor specific real time PCR assays for detection of minimal residual disease usin IRCCS AOU San Martino IST (Genova) Pfeffer Ulrich CLI Oncology 2 Translational Cancer Biomarkers CBSS early detection of cardiotoxicity in cancer patients ONCOLOGICO DI BARI Oliva Stefano CLI Cardiovascular and Cardiac Contractility, Hypertrophy, and Failure CCHF Planar haptic device and virtual reality tools for hand and finger rehabilitation S.CAMILLO Oboe Roberto CLI Musculoskeletal, Oral and Musculoskeletal Rehabilitation Sciences MRS Improved pre surgical evaluation of the human epileptogenic zone with a novel intracranial recording/analysis platform CARLO BESTA Gnatkovsky Vadym BIO Brain Disorders and Acute Neural Injury and Epilepsy ANIE Docetaxel, Cisplatin and 5 Fluorouracil followed by concomitant Radiotherapy and PF in Locally advanced Head and Neck carcinoma: A phase II study proposal Lombardia Mandalà Mario CLI Oncology 2 Translational Oncology Development and optimization of a dedicated selfshielded system to perform accelerated partial breast irradiation in prone position after breast conserving surgery. REGINA ELENA SORIANI ANTONELLA CLI Oncology 2 Translational Radiation Therapeutics and Biology RTB Pagina 2 di 6

3 A Phase II Randomized Multicentre Study of SystemicChemotherapy versus Systemic Chemotherapy plus SIR Spheres as SecondLine in KRAS Mutant Unresectable Colorectal Liver Metastases (SITILO 2) Lazio Cosimelli Maurizio CLI Oncology 2 Translational Oncology Integrated lipidomic profiling in diabetes, cardiovascular disease and cancer in a cohort of subjects in a mediterranean area of southern Italy: a nested case control study. DE BELLIS Caruso Maria Gabriella BIO Population Sciences and Epidemiology Kidney, Nutrition, Obesity and Diabetes KNOD GOAL DIRECTED PERFUSION AND ACUTE KIDNEY INJURY IN CARDIAC SURGERY A RANDOMIZED, CONTROLLED TRIAL SAN DONATO Ranucci Marco CLI Surgical Sciences, Biomedical Imaging, and Bioengineering Surgery, Anesthesiology, and Trauma SAT Standardizing tissue handling in pre analytical procedures: technological, environmentally safe innovation in solid tumour processing. Piemonte Sapino Anna CLI Healthcare Delivery and FREMS for Acute Inflammatory Bowel Disease: a Phase I/II trial Lazio COSTAMAGN GUIDO CLI Digestive, Kidney and Urological Systems Digestive Sciences Small Business Activities SBIR/STTR SBDI Hyperthophic cardiomyopathy: new insights from deep sequencing and psycosocial evaluation. Lombardia Merlini Piera Angelica CLI Cardiovascular and Cardiac Contractility, Hypertrophy, and Failure CCHF Cost Utility of Conventional Hemodialysis (CHD) versus Short Daily Hemodialysis (SDHD) for patients coming from Automated Peritoneal Dialysis (APD): A randomized controlled trial Puglia Gesualdo Loreto CLI Healthcare Delivery and ß amyloid control of peripheral and neuronal glucose uptake NEUROMED Nicoletti Ferdinando BIO Brain Disorders and Cell Death in Neurodegeneration CDIN Pagina 3 di 6

4 Project title: Safety and Effectiveness of H.E.L.P. apheresis in microcirculatory diseases refractory to standard care Emilia Romagna MARIANO MARIA CLI Cardiovascular and Physiology and Pathobiology of Cardiovascular and Respiratory Systems PPCR Laser Treatment of Haemophilic Hypertrophic Synovia Toscana DEMARTIS FRANCESCO CLI Musculoskeletal, Oral and Arthritis, Connective Tissue and Skin ACTS Development of brain targeted epigenetic drugs for the treatment of neurodegenerative disorders and brain ischemia S.CAMILLO Pizzi Marina BIO Brain Disorders and Brain Injury and Neurovascular Pathologies BINP UNRESECTABLE IN TRANSIT METASTATIC MELANOMA: ELECTROCHEMO THERAPY VERSUS ELECTROIMMUNOTHERAPY. LOCAL AND SYSTEMIC EFFECTS. PASCALE Nicola Mozzillo CLI Oncology 2 Translational Oncology Sebum lipidomics: a new tool to correlate skin and systemic lipid metabolism. SAN GALLICANO Picardo Mauro BIO Musculoskeletal, Oral and Musculoskeletal, Oral and Skin Sciences Small Business SEMO Development of a miniaturized, automated assay for the diagnosis of rare diseases Piemonte ROCCATELLO DARIO BIO Bioengineering Sciences and Technologies Instrumentation and Systems Development ISD Metabotropic glutamate receptors as a target for the treatment of Amyotrophic Lateral Sclerosis NEUROMED Bruno Valeria BIO Brain Disorders and and Neurodegeneration CNN Type 3 metabotropic glutamate receptors expressed by cancer stem cells as drug targets in the experimental treatment of malignant gliomas NEUROMED Battaglia Giuseppe BIO Brain Disorders and Neuroimmunology and Brain Tumors CNBT Pagina 4 di 6

5 Role of SAMITAL in prevention of chemo radiation (CT/RT) induced oral mucositis in cancer patients. A Phase 2 Randomized Controlled trial in adults and a feasibility study in paediatric patients I. O. V. Sotti Guido CLI Oncology 2 Translational Oncology Impact assessment of Training Centre for Integrated Health Emergency Emilia Romagna Camellini Marcella CLI Healthcare Delivery and Development of pre operative investigation tools and surgical procedures for the treatment of movement disorders in childhood OSPEDALE BAMBINO GESU' Marras Carlo BIO Brain Disorders and Developmental Brain Disorders DBD A new automatic device for personalized clinical monitoring of thrombotic and hemorraghic risk assessment in cancer patients C.R.O. AVIANO Mazzucato Mario BIO Oncology 2 Translational Oncology 2 Translational Small Business [SBIR/STTR] Radiation Therapy and Biology SETA] ANTIOXIDANT TREATMENT TO PREVENT BIOMEDICAL HAZARDS OF CYCLIC VARIATIONS OF SOLAR ACTIVITY SAN DONATO LUZI LIVIO BIO Endocrinology, Metabolism, Nutrition and Reproductive Sciences Endocrinology, Metabolism, Nutrition and Reproductive Sciences (EMNR) Integrated Review Group Fellowship Panel F Haemophilia arthropathy (HA) and Ultrasound (US): development and first validation steps of the simplified HEAD US score Liguria Martinoli Carlo CLI Musculoskeletal, Oral and Arthritis, Connective Tissue and Skin ACTS Use of a new material (polipropilene biofilm) with coated nanoparticles for the release of antibacterial drugs instead of surgical mesh for the reconstructive surgery of pelvic floor. Lazio Angioli Roberto BIO Digestive, Kidney and Urological Systems Renal and Urological Sciences Small Business Activities SERU Pagina 5 di 6

6 Nerve Growth Factor eye drops as a novel treatment for vision loss in patients with Retinitis Pigmentosa: from preclinical to clinical Phase II trial. SAN RAFFAELE MONTE TABOR Rama Paolo CLI Brain Disorders and Neuroplasticity and Neurotransmitters CNNT "Preventative strategies against dementia: clinical, biological and anthropological impact of long term treatment with anti oxidants in mild cognitive impairment" Umbria Parnetti Lucilla CLI Brain Disorders and and Neurodegeneration CNN Development of new IVD CE molecular diagnostic tests for the detection of epigenetic defects involved in human disease MAGGIORE Miozzo Monica Rosa BIO Genes, Genomes and Genetics Genetics of Health and Disease GHD Phase II trial of fulvestrant and gefitinib combination in patients with EGFR mutations who failed a first line with EGFR Tyrosine Kinase Inhibitors (TKIs) ISTITUTO TUMORI MILANO GARASSINO MARINA CHIA CLI Oncology 2 Translational Oncology The overexpression of ANGPTL4 is involved in the inhibition of proliferation of human gastric cancer cell line MKN 45. Study of the effects of ANGPTL4 in invasiveness and metastasis. Development of effective approach for cancer therapy. PASCALE BONELLI PATRIZIA BIO Oncology 1 Basic Translational Molecular Oncogenesis MONC Effect of telemedicine on Haemophilia Management, Treatment Effectiveness and Patient's Quality of Life Abruzzo Dragani Alfredo CLI Healthcare Delivery and Porous titanium combined with an osteoinductive hydrogel and cells: an innovative strategy to improve prosthetic implants osteointegration GALEAZZI Banfi Giuseppe BIO Musculoskeletal, Oral and Musculoskeletal, Oral and Skin Sciences Small Business SEMO Honey and other hive products free from pharmaceutical or environmental residues: innovative, automated honey bee farming system Istituto Zooprofilattico Sperimentale del Lazio e della Toscana Formato Giovanni BIO Veterinary Food Safety FOSA Pagina 6 di 6