Monoclonal Antibodies, Brochure

Transcription

1 Monoclonal Antibodies, Brochure Interest in any of the products, request or order them at Bio-Connect Diagnostics. Bio-Connect Diagnostics B.V. T NL +31 (0) T BE +32 (0) Begonialaan 3a F NL +31 (0) F BE +32 (0) TE Huissen E info@bio-connectdiagnostics.nl The Netherlands W

2 High Affinity Monoclonal Antibodies

3 Randox Life Sciences is a recognised primary manufacturer of high quality, cost-effective human recombinant proteins, polyclonal and monoclonal antibodies which can be used for a wide variety of research and development applications. Randox Life Sciences products are manufactured at our ISO certified manufacturing plant in the United Kingdom using state of the art facilities. Our product range includes over 200 antibodies and over 100 human recombinant proteins, including both classical and novel markers. The quality systems within Life Sciences are monitored regularly both internally and externally enabling us to provide reliable and consistent products of the highest quality. Monoclonal antibodies Randox Life Sciences produces monoclonal antibodies which offer several advantages over polyclonal antibodies: All Monoclonal antibodies within a batch consist of single antibody molecules that bind to a particular epitope on the antigen Monoclonal antibodies bind to only one epitope which allows the selection of certain desirable characteristics including: - Specificity - as the antibody only binds to one specific region, it is possible to produce a highly specific antibody for the required target. Alternatively, a generic antibody can also be produced that binds to a common epitope on all cross reactants - Affinity - each antibody molecule binds to the target with the same affinity therefore it is possible to produce monoclonal antibodies with extremely high affinity - Specific monoclonal antibodies can be produced in animals that are immunised with impure immunogen meaning undesirable cross reactivity can be eliminated General monoclonal specification Host Animal: Sheep Format: Purified high affinity monoclonal antibody ph: 7.2 Buffer: PBS Preservative: 0.09% Sodium Azide Method of Production: In vitro cell culture using standard DMEM media supplemented with foetal bovine serum of a USDA approved origin Method of Purification: Protein A Affinity Chromatography

4 Drug Residues Estradiol Methylprednisolone Norfloxacin Progesterone Salbutamol SEM Tetracycline Biochemical markers 17a Hydroxy Progesterone Apolioprotein E4 Cortisol Creatinine DHEA-S Glutathione S-Transferase Omega 1 Mutant Glutathione S-Transferase Omega 1 Wild-Type Granulocyte Macrophage Colony Stimulating Factor Intercellular Adhesion Molecule 1 Intercellular Adhesion Molecule 2 L-Selectin Thyroid Stimulating Hormone Beta Specific - Capture Clone 3 - Detector Clone 4 Vascular Cellular Adhesion Molecule Drugs of Abuse EDDP Norketamine Normeperidine Secobarbital TCA ETG ctni Epitopes Epitope 1-20 Epitope 1-20 Detector 1 Epitope Detector 2 Epitope Epitope Epitope Epitope Capture Epitope FABP Fatty Acid Binding Protein (FABP) Clone 1 Fatty Acid Binding Protein (FABP) Clone 2 Fatty Acid Binding Protein (FABP) Capture Clone 3 Fatty Acid Binding Protein (FABP) Detector Clone 4

5 Custom manufacturing services With over 185 research scientists and almost 30 years experience in commercial assay development Randox Life Sciences can provide a tailor made assay development service to meet your specifications. Randox Life Sciences customisation service has proved incredibly successful in the research and development industries, allowing the customer to use our expertise to obtain the antibody and/or protein most relevant to their line of work. Customised antibodies are available from weeks after primary immunisation, although prolonged immunisation may be necessary to meet the required specifications. As well as antibodies, Randox Life Sciences can provide labelled conjugates upon request. Order online: Randox Life Sciences, 55 Diamond Road, Crumlin, County Antrim, BT29 4QY, United Kingdom t +44 (0) f +44 (0) e lifesciences@randox.com I Information correct at time of print. Randox Laboratories Limited is a company registered within Northern Ireland with company number N.I VAT Registered Number: GB Product availability may vary from country to country. Please contact your local Randox representative for information. LT233 JUN13