Immune System. Daryl Beatty Brazosport College Anatomy & Physiology II

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1 Immune System Daryl Beatty Brazosport College Anatomy & Physiology II

2 21 The Immune System: Innate and Adaptive Body Defenses

3 Which of the following best describes the immune system? a. the set of organs that are collectively called the immune system b. the organ set that accumulates pathogens and kills them c. the diverse set of molecules and immune cells that are found in lymphoid tissue and body fluids d. antibodies

4 Which of the following best describes the immune system? c. the diverse set of molecules and immune cells that are found in lymphoid tissue and body fluids

5 Which of the following act as the first line of defense against foreign pathogens? a. skin b. lymphocytes c. mucous membranes d. both a and c

6 Which of the following act as the first line of defense against foreign pathogens? a. skin c. mucous membranes d. both a and c

7 The two intrinsic defense systems have many components. Which of the following cell types is NOT a contributor to specific immunity? a. natural killer cells b. plasma cells c. B cells d. T cells

8 The two intrinsic defense systems have many components. Which of the following cell types is NOT a contributor to specific immunity? a. natural killer cells

9 Which of the following is/are a mechanical barrier to pathogen invasion? a. mucus b. lysozyme in tears c. saliva d. interferon

10 Which of the following is/are a mechanical barrier to pathogen invasion? a. mucus

11 Macrophages are derived from. a. megakaryocytes b. monocytes c. T lymphocytes d. plasma cells

12 Macrophages are derived from. b. monocytes

13 In order for some phagocytes to destroy certain pathogens, like tuberculosis, they have ingested, must be deployed. a. lysosomes b. diapedesis c. the respiratory burst d. complement

14 In order for some phagocytes to destroy certain pathogens, like tuberculosis, they have ingested, must be deployed. c. the respiratory burst

15 and are the most common phagocytic cells in the blood. a. Neutrophils eosinophils b. Eosinophils monocytes c. Neutrophils.monocytes d. Natural killer cells eosinophils

16 and are the most common phagocytic cells in the blood. c. Neutrophils.monocytes

17 What characteristic do all inflammatory chemicals share? a. they are all a type of histamine b. they all help stop bleeding c. they are all vasodilators d. they are all secreted by macrophages

18 What characteristic do all inflammatory chemicals share? c. they are all vasodilators

19 An increase in white blood cell number at sites of injury, characteristic of inflammation is called. a. chemotaxis b. leukocytosis c. leukemia d. diapedesis

20 An increase in white blood cell number at sites of injury, characteristic of inflammation is called. b. leukocytosis

21 The process by which phagocytes exit capillaries and enter injured tissue is called. a. chemotaxis b. leukocytosis c. leukemia d. diapedesis

22 The process by which phagocytes exit capillaries and enter injured tissue is called. d. diapedesis

23 Your hand has a scratch. What signals would indicate that the injury is inflamed? a. cold, gray, sunken, numb b. yellow, not swollen, tingling, normal temperature c. red, hot, swollen, painful d. no change to the site other than evidence of the scratch

24 Your hand has a scratch. What signals would indicate that the injury is inflamed? c. red, hot, swollen, painful

25 A patient has contracted the Hepatitis C virus. Which of the following drug therapies might be effective? a. aspirin b. interferon c. penicillin d. ibuprofen

26 A patient has contracted the Hepatitis C virus. Which of the following drug therapies might be effective? b. interferon

27 The basic mechanism employed by complement to fight bacterial infections is. a. antibody production b. fever elevation c. bacterial cell membrane lysis d. antiviral protein synthesis

28 The basic mechanism employed by complement to fight bacterial infections is. c. bacterial cell membrane lysis

29 The process of attaching complement proteins to the bacterial cell wall to enhance phagocytosis is called. a. optimization b. MAC attachment c. lysis d. opsonization

30 The process of attaching complement proteins to the bacterial cell wall to enhance phagocytosis is called. d. opsonization

31 What would be the body s response if the hypothalamus detected pyrogens? a. an increase in body temperature set point b. mobilization of lymphocytes from the bone marrow c. increased sweating to lower body temperature d. complement inhibition

32 What would be the body s response if the hypothalamus detected pyrogens? a. an increase in body temperature set point

33 Which of the following materials or compounds would be the most highly immunogenic? a. non-self antibody b. plastic c. hapten d. self antibody

34 Which of the following materials or compounds would be the most highly immunogenic? a. non-self antibody

35 The presence of proteins make it possible for our immune system to differentiate between our cells and those that are foreign. a. antigenic determinants b. MHC proteins c. haptens d. antibodies

36 The presence of proteins make it possible for our immune system to differentiate between our cells and those that are foreign. b. MHC proteins

37 The adaptive immune system involves three major cell types: antigen-presenting cells, T cells, which constitute immunity, and B cells, which govern immunity. a. nonspecific specific b. antigenic allergic c. MHC MAC d. cell-mediated humoral

38 The adaptive immune system involves three major cell types: antigen-presenting cells, T cells, which constitute immunity, and B cells, which govern immunity. d. cell-mediated humoral

39 become antigenic if they attach themselves to larger proteins. a. Haptens b. Antigenic determinants c. Pyrogens d. MHC proteins

40 become antigenic if they attach themselves to larger proteins. a. Haptens

41 Why would a patient with no thymus lack an effective humoral immune response? a. B cells develop into plasma cells in the thymus b. T cells are responsible for humoral immunity c. B cells are produced in the thymus d. certain T cells are required to activate B cells into antibodyproducing cells

42 Why would a patient with no thymus lack an effective humoral immune response? d. certain T cells are required to activate B cells into antibodyproducing cells

43 Lymphocytes are educated within primary lymphoid organs. B cells are educated in the while T cells are educated in the. a. bone marrow thymus b. thymus bone marrow c. bone marrow bone marrow d. thymus thymus

44 Lymphocytes are educated within primary lymphoid organs. B cells are educated in the while T cells are educated in the. a. bone marrow thymus

45 During clonal selection of B cells, those B cells with complementary membrane receptors to the invading antigen will differentiate into cells. a. humoral b. clonal c. plasma d. B cells

46 During clonal selection of B cells, those B cells with complementary membrane receptors to the invading antigen will differentiate into cells. c. plasma

47 The basis of long lasting immunity is the presence of cells. a. plasma b. memory c. clonal d. humoral

48 The basis of long lasting immunity is the presence of cells. b. memory

49 A patient has been immunized against chicken pox. What type of immunity is this? a. naturally acquired passive b. artificially acquired passive c. naturally acquired active d. artificially acquired active

50 A patient has been immunized against chicken pox. What type of immunity is this? d. artificially acquired active

51 In which class of molecules are antibodies classified? a. carbohydrates b. lipids c. nucleic acids d. proteins

52 In which class of molecules are antibodies classified? d. proteins

53 Of the following classes of antibodies, which can cross the placenta? a. IgG b. IgA c. IgM d. IgD

54 Of the following classes of antibodies, which can cross the placenta? a. IgG

55 Which of the following best describes an antibody s mode of action? a. antibodies punch holes in the cell membrane b. antibodies immobilize antigens and mark them for destruction c. antibodies bind to antigens and escort them to the liver for excretion d. antibodies secrete antimicrobial proteins

56 Which of the following best describes an antibody s mode of action? b. antibodies immobilize antigens and mark them for destruction

57 How are T cells introduced to antigens? a. T cells bind to and phagocytose antigens b. antibodies immobilize the antigens for T cell recognition c. antigen-presenting cells link antigenic peptides to MHC proteins to which T cells will attach d. T cells wait in the blood until an antigen collides with them

58 How are T cells introduced to antigens? c. antigen-presenting cells link antigenic peptides to MHC proteins to which T cells will attach

59 How is the cytotoxic T cell mechanism of action similar to that of complement? a. cytotoxic T cells activate B cells to produce antibodies b. cytotoxic T cells induce cell lysis with perforin, a protein similar to complement s MAC c. cytotoxic T cells make up the complement system d. cytotoxic T cells are antigenpresenting cells

60 How is the cytotoxic T cell mechanism of action similar to that of complement? b. cytotoxic T cells induce cell lysis with perforin, a protein similar to complement s MAC

61 When antibodies develop against a person s own cells, this is an example of a/an. a. delayed hypersensitivity b. immediate hypersensitivity c. allergy d. autoimmune disease

62 When antibodies develop against a person s own cells, this is an example of a/an. d. autoimmune disease

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