The Body s Defenses CHAPTER 24

Save this PDF as:
 WORD  PNG  TXT  JPG

Size: px
Start display at page:

Download "The Body s Defenses CHAPTER 24"

Transcription

1 CHAPTER 24 The Body s Defenses PowerPoint Lectures for Essential Biology, Third Edition Neil Campbell, Jane Reece, and Eric Simon Essential Biology with Physiology, Second Edition Neil Campbell, Jane Reece, and Eric Simon Lectures by Chris C. Romero

2 Biology and Society: The Next Pandemic? A vaccine is a harmless derivative or variant of a disease-causing microbe. In many industrialized nations, Vaccination programs have eliminated previously feared viral disease.

3 A permanent vaccination for the influenza virus has yet to be developed. This virus has been responsible for some of the deadliest pandemics of the twentieth century.

4 Some medical researchers fear that a pandemic may start from a newly discovered strain of influenza virus called the avian flu.

5 Nonspecific Defenses Three lines of defense protect us from invaders of varying types.

6 Figure 24.2

7 The human body s first line of defense is a set of physical barriers and chemical agents that prevent foreign invaders from getting inside.

8 External Barriers The body has several physical barriers: An outer layer of intact skin Hair in the nostrils Mucous membranes

9 Cilia

10 Figure 24.3

11 In addition, the body also employs nonspecific chemical defenses: Sweat, saliva, and tears contain antimicrobial chemicals. Glands produce oils and acids.

12 Internal Defenses When an invader penetrates the body s external barriers, a set of nonspecific internal defenses that depend mostly on white blood cells acts as a second line of defense.

13 Figure 24.4

14 Other nonspecific internal defenses include proteins that either attack microbes directly or impede their reproduction.

15 Figure 24.5

16 The Inflammatory Response The inflammatory response Is a coordinated set of nonspecific defenses in response to damaged cells.

17 Figure 24.6

18 Damaged cells release histamine and prostaglandins that increase blood flow to the damaged area.

19 The Lymphatic System The lymphatic system

20 Figure 24.7

21 The lymphatic system has two main functions: Return tissue fluid to the circulatory system Fight infection

22 The organs of the lymphatic system are lymph nodes, packed with white blood cells that fight infection.

23 Specific Defenses: The Immune System The immune system Consists of a large collection of cells that work together to present a specific response to infection.

24 Antigens Are foreign substances that elicit an immune response. Antibodies Are proteins found in blood plasma that attach to one particular kind of antigen and help counter its effects.

25 In addition to being specific, the immune system can remember antigens and react more promptly to second exposures to infection.

26 Immunity Is resistance to specific invaders. Is usually acquired by natural infection.

27 Vaccinations Trigger active immunity, stimulating the body to defend itself.

28 Passive immunity Is acquired by receiving premade antibodies.

29 Recognizing the Invaders Lymphocytes Lymphocytes Are white blood cells found most often in the lymphatic system. Produce the immune response. Originate from stem cells in the bone marrow.

30 There are two kinds of lymphocytes: B cells, which develop in the bone marrow T cells, which become specialized in the thymus

31 Figure 24.9

32 In the humoral immune response, B cells secrete antibodies as a form of defense. In the cell-mediated immune response, T cells circulate in the blood and lymph, attacking infected body cells.

33 When T or B cells develop, the cell synthesizes molecules of a specific protein and builds them into its plasma membrane.

34 Antibodies Antibodies produced by B-cells Are proteins that serve as molecular weapons of defense. Contain four polypeptide chains arranged in a Y shape. Antibodies

35 Figure 24.10

36 An antibody molecule has two related functions in humoral immunity: Recognize and bind to a certain antigen By binding to it, help to counter its effect

37 Responding to the Invaders The immune system stops infections by destroying antigen-bearing invaders.

38 B Cells and Clonal Selection Clonal selection Is a process by which the immune system can defend against almost an infinite variety of antigens.

39 Clonal selection in B cells Role of B Cells

40 Figure 24.11

41 Monoclonal antibodies Are the antibodies produced by a single clone.

42 Immunological Memory The primary immune response takes several days to produce effector cells via clonal selection. Clonal selection also produces memory cells, which can last decades in the lymph nodes.

43 The secondary immune response Is produced when the same antigen is encountered again. Is initiated much faster due to the presence of memory cells.

44 T Cells T cells Respond to pathogens that have already entered body cells.

45 Helper T cells Bind to other white blood cells that have previously encountered an antigen. Helper T Cells

46 Figure 24.12

47 A helper T cell is activated by the binding of a T cell receptor to a self-nonself complex.

48 Figure 24.13

49 Cytotoxic T cells Are the only T cells that actually kill other cells. Cytotoxic T Cells T Cell Receptors

50 Figure 24.14

51 Immune Disorders If the interplay of immune cells malfunctions, problems in the immune response can result.

52 Allergies Allergies Are abnormal sensitivities to antigens in the environment. Allergens Are antigens that cause allergies.

53 The symptoms of an allergy result from a two-stage reaction sequence.

54 Figure 24.15

55 Anaphylactic shock Is an especially dangerous type of allergic reaction. Can be counteracted with injections of epinephrine.

56 Figure 24.16

57 Autoimmune Diseases The body s immune system Normally reacts only against foreign (nonself) substances. Generally rejects transplanted organs, whose cells lack the recipient s unique fingerprint of self proteins.

58 In autoimmune diseases The immune system turns against the body s own molecules.

59 Figure 24.17

60 Immunodeficiency Diseases In immunodeficiency diseases, Immune components are lacking, and infections recur.

61 Immunodeficiencies May arise through inborn conditions or from disease.

62 AIDS AIDS is a worldwide epidemic that kills millions of people each year. HIV, the AIDS virus, Attacks helper T cells, crippling both humoral and cell-mediated immunity.

63 Practicing safer sex can prevent the spread of HIV and save many lives.

64 Figure 24.18

65 Evolution Connection: HIV Evolution HIV has one of the fastest rates of mutation of any pathogen ever studied. HIV Reproductive Cycle

66 Figure 24.19

67 Drug-resistant HIV strains are now being documented in newly infected patients, Exhibiting how this virus readily adapts through natural selection.

Antigens have specific regions where antibodies bind to them Antigens are usually molecules on the surface of viruses or foreign cells Antigenic

Antigens have specific regions where antibodies bind to them Antigens are usually molecules on the surface of viruses or foreign cells Antigenic Bio 100 Guide 22 Antigens have specific regions where antibodies bind to them Antigens are usually molecules on the surface of viruses or foreign cells Antigenic determinants are the specific regions on

More information

10. T and B cells are types of a. endocrine cells. c. lymphocytes. b. platelets. d. complement cells.

10. T and B cells are types of a. endocrine cells. c. lymphocytes. b. platelets. d. complement cells. Virus and Immune System Review Directions: Write your answers on a separate piece of paper. 1. Why does a cut in the skin threaten the body s nonspecific defenses against disease? a. If a cut bleeds, disease-fighting

More information

The Immune System. 2 Types of Defense Mechanisms. Lines of Defense. Line of Defense. Lines of Defense

The Immune System. 2 Types of Defense Mechanisms. Lines of Defense. Line of Defense. Lines of Defense The Immune System 2 Types of Defense Mechanisms Immune System the system that fights infection by producing cells to inactivate foreign substances to avoid infection and disease. Immunity the body s ability

More information

One of the more complex systems we re looking at. An immune response (a response to a pathogen) can be of two types:

One of the more complex systems we re looking at. An immune response (a response to a pathogen) can be of two types: Immune system. One of the more complex systems we re looking at. An immune response (a response to a pathogen) can be of two types: (pathogen - disease causing organism) 1) Non specific. Anything foreign

More information

11/20/2011. Outline. Immune System Function. Terminology. Two Types of Immune Defense. Innate Immunity = Non Specific

11/20/2011. Outline. Immune System Function. Terminology. Two Types of Immune Defense. Innate Immunity = Non Specific Chapter 43 Immune System Outline I. Nonspecific Defenses A. Barrier B. Protective proteins C. Phagocytes D. Natural killer cells E. Inflammatory reaction II. Specific Defenses A. B cells Antibody mediated

More information

ANIMALS FORM & FUNCTION BODY DEFENSES NONSPECIFIC DEFENSES PHYSICAL BARRIERS PHAGOCYTES. Animals Form & Function Activity #4 page 1

ANIMALS FORM & FUNCTION BODY DEFENSES NONSPECIFIC DEFENSES PHYSICAL BARRIERS PHAGOCYTES. Animals Form & Function Activity #4 page 1 AP BIOLOGY ANIMALS FORM & FUNCTION ACTIVITY #4 NAME DATE HOUR BODY DEFENSES NONSPECIFIC DEFENSES PHYSICAL BARRIERS PHAGOCYTES Animals Form & Function Activity #4 page 1 INFLAMMATORY RESPONSE ANTIMICROBIAL

More information

Chapter 43: The Immune System

Chapter 43: The Immune System Name Period Our students consider this chapter to be a particularly challenging and important one. Expect to work your way slowly through the first three concepts. Take particular care with Concepts 43.2

More information

specific B cells Humoral immunity lymphocytes antibodies B cells bone marrow Cell-mediated immunity: T cells antibodies proteins

specific B cells Humoral immunity lymphocytes antibodies B cells bone marrow Cell-mediated immunity: T cells antibodies proteins Adaptive Immunity Chapter 17: Adaptive (specific) Immunity Bio 139 Dr. Amy Rogers Host defenses that are specific to a particular infectious agent Can be innate or genetic for humans as a group: most microbes

More information

Immune system. Nonspecific response: inflammation. Inflammation : the beginning. Nonspecific immunity vs. Adaptive immunity

Immune system. Nonspecific response: inflammation. Inflammation : the beginning. Nonspecific immunity vs. Adaptive immunity Immune system Body must resist disease in order to function Defends against pathogens, identifies and destroys abnormal cells. The primary pathogens are bacteria and viruses. Nonspecific immunity vs. Adaptive

More information

Name (print) Name (signature) Period. (Total 30 points)

Name (print) Name (signature) Period. (Total 30 points) AP Biology Worksheet Chapter 43 The Immune System Lambdin April 4, 2011 Due Date: Thurs. April 7, 2011 You may use the following: Text Notes Power point Internet One other person in class "On my honor,

More information

Chapter 22: The Lymphatic System and Immunity

Chapter 22: The Lymphatic System and Immunity Chapter 22: The Lymphatic System and Immunity Introduction Immune system the body s defenses against pathogens that produce disease 2 types of immunity Nonspecific immune mechanisms (Innate immunity) Provide

More information

CHAPTER 35 HUMAN IMMUNE SYSTEM STANDARDS:SC.912.L.14.52 & SC.912.L.14.6

CHAPTER 35 HUMAN IMMUNE SYSTEM STANDARDS:SC.912.L.14.52 & SC.912.L.14.6 CHAPTER 35 HUMAN IMMUNE SYSTEM STANDARDS:SC.912.L.14.52 & SC.912.L.14.6 SECTION 1 - Infectious Disease 1.Identify the causes of infectious disease. 2.Explain how infectious diseases are spread. Causes

More information

Lymphatic System - Structures

Lymphatic System - Structures Lymphatic System - Structures Lymphatic vessels Lymphatic tissues and organs 1 Lymphatic System - Functions Returns leaked plasma to blood vessels Cleanses lymph of bacteria & other foreign matter Provides

More information

Introduction. Skin. The Immune System. Chapter 51

Introduction. Skin. The Immune System. Chapter 51 The Immune System Chapter 51 Introduction Vertebrates have three levels of defenses -1. The Integumentary System -Skin and mucous membranes provide first line of defense -2. Nonspecific (innate) Immune

More information

Immune System and Disease

Immune System and Disease Immune System and Disease Homeostasis Q: How does the body fight against invading organisms that may disrupt homeostasis? WHAT I KNOW WHAT I LEARNED 35.1 How do people catch infectious diseases? SAMPLE

More information

Supplemental Material CBE Life Sciences Education. Su et al.

Supplemental Material CBE Life Sciences Education. Su et al. Supplemental Material CBE Life Sciences Education Su et al. APPENDIX Human Body's Immune System Test This test consists of 31 questions, with only 1 answer to be selected for each question. Please select

More information

Assignment. Write a two page essay describing the differences between specific and non- specific immunity

Assignment. Write a two page essay describing the differences between specific and non- specific immunity Assignment Write a two page essay describing the differences between specific and non- specific immunity 1 The Immune System 2 I. Immunity A. defense against invading parasites and abnormal cells B. Types:

More information

Bio 20 Chapter 11 Workbook Blood and the Immune System Ms. Nyboer

Bio 20 Chapter 11 Workbook Blood and the Immune System Ms. Nyboer Bio 20 Chapter 11 Workbook Blood and the Immune System Ms. Nyboer Name: Part A: Components of Blood 1. List the 3 plasma proteins and describe the function of each Albumins osmotic balance Globulins antibodies,

More information

2) Macrophages function to engulf and present antigen to other immune cells.

2) Macrophages function to engulf and present antigen to other immune cells. Immunology The immune system has specificity and memory. It specifically recognizes different antigens and has memory for these same antigens the next time they are encountered. The Cellular Components

More information

Chapter 22: The Lymphatic System and Immunity

Chapter 22: The Lymphatic System and Immunity Bio40C schedule Lecture: Immune system Lecture exam 2 postponed to Tu Feb 23 covers Ch 22, 26, 27 Multiple choice and short answer Study guides posted on website Extra credit total of 15 pts Work sheets

More information

Microbiology AN INTRODUCTION EIGHTH EDITION

Microbiology AN INTRODUCTION EIGHTH EDITION TORTORA FUNKE CASE Microbiology AN INTRODUCTION EIGHTH EDITION Differentiate between innate and acquired immunity. Chapter 17 Specific Defenses of the Host: The Immune Response B.E Pruitt & Jane J. Stein

More information

Lecture 7 Immunology

Lecture 7 Immunology Slide 1 Lecture 7 Immunology Structure Components Leukocytes Lymphoid tissue Recognition of self Innate Immunity Physical and chemical barriers Phagocytosis Inflammation Adaptive immunity Humoral responses

More information

Human Immunity. How our body s cells defend against microbial and viral invaders

Human Immunity. How our body s cells defend against microbial and viral invaders Human Immunity How our body s cells defend against microbial and viral invaders What is Immunity? The word immunity comes from the Latin immunus meaning free of burden. Thus; it is a body s general ability

More information

Immune response is a response by your immune system to some type of pathogen. A pathogen is a disease causing organism.

Immune response is a response by your immune system to some type of pathogen. A pathogen is a disease causing organism. Immune system. This is one of the more complex systems we re looking at, mostly because we need to look at the cellular level to really understand what's going on. First some definitions: Immune response

More information

AP BIOLOGY 2007 SCORING GUIDELINES (Form B)

AP BIOLOGY 2007 SCORING GUIDELINES (Form B) AP BIOLOGY 2007 SCORING GUIDELINES (Form B) Question 2 The defenses of the human body to the entry and establishment of a pathogen (disease-causing organism) can be divided into nonspecific responses and

More information

Figure 14.2 Overview of Innate and Adaptive Immunity

Figure 14.2 Overview of Innate and Adaptive Immunity I M M U N I T Y Innate (inborn) Immunity does not distinguish one pathogen from another Figure 14.2 Overview of Innate and Adaptive Immunity Our first line of defense includes physical and chemical barriers

More information

Pathogens and the immune system

Pathogens and the immune system Review of lecture 7 Pathogens and the immune system Veronica Leautaud, Ph.D. vl2@ rice.edu BRC 511 / 530-lab Lecture 8 BIOE 301-Bioengineering and World Health Science Science is the human activity of

More information

Pathogens and the immune system

Pathogens and the immune system Pathogens and the immune system Veronica Leautaud, Ph.D. vl2@ rice.edu BRC 511 / 530-lab Lecture 8 BIOE 301-Bioengineering and World Health Review of lecture 7 Science Science is the human activity of

More information

The Human Immune System

The Human Immune System The Human Immune System What is the immune system? The body s defense against disease causing organisms, malfunctioning cells, and foreign particles The First Line of Defense Skin The dead, outer layer

More information

Immunity Unit Test Z

Immunity Unit Test Z Immunity Unit Test Z Name MB Multiple Choice Identify the choice that best completes the statement or answers the question. 1. Which of the pathogens in Figure 31.1 cause disease by taking over healthy

More information

Lymphatic and Immune Systems Homeostatic role of defense against pathogens, injury, diseased body cells, and toxins.

Lymphatic and Immune Systems Homeostatic role of defense against pathogens, injury, diseased body cells, and toxins. Lymphatic and Immune Systems Homeostatic role of defense against pathogens, injury, diseased body cells, and toxins Requires both lymph and immune systems to be effective Three levels of defense 1.Skin,

More information

The Immune System: A Tutorial

The Immune System: A Tutorial The Immune System: A Tutorial Modeling and Simulation of Biological Systems 21-366B Shlomo Ta asan Images taken from http://rex.nci.nih.gov/behindthenews/uis/uisframe.htm http://copewithcytokines.de/ The

More information

Immune System Memory Game

Immune System Memory Game Immune System Memory Game Recommended Age: 12 years old Time: 45 minutes Everyday our bodies come in contact with millions of tiny organisms and particles that could potentially make us sick. Despite this,

More information

1) Siderophores are bacterial proteins that compete with animal A) Antibodies. B) Red blood cells. C) Transferrin. D) White blood cells. E) Receptors.

1) Siderophores are bacterial proteins that compete with animal A) Antibodies. B) Red blood cells. C) Transferrin. D) White blood cells. E) Receptors. Prof. Lester s BIOL 210 Practice Exam 4 (There is no answer key. Please do not email or ask me for answers.) Chapters 15, 16, 17, 19, HIV/AIDS, TB, Quorum Sensing 1) Siderophores are bacterial proteins

More information

The Immune System and Disease

The Immune System and Disease Chapter 40 The Immune System and Disease Section 40 1 Infectious Disease (pages 1029 1033) This section describes the causes of disease and explains how infectious diseases are transmitted Introduction

More information

Immune System. Daryl Beatty Brazosport College Anatomy & Physiology II

Immune System. Daryl Beatty Brazosport College Anatomy & Physiology II Immune System Daryl Beatty Brazosport College Anatomy & Physiology II 21 The Immune System: Innate and Adaptive Body Defenses Which of the following best describes the immune system? a. the set of organs

More information

Chapter 39 - The Body Defenses

Chapter 39 - The Body Defenses Chapter 39 - The Body Defenses Immunity - refers to the body s ability to resist or eliminate potentially harmful foreign material s or abnormal cells Mechanisms include: 1. Defense against invading pathogens

More information

Lymph Transport and Immunity

Lymph Transport and Immunity Lymph Transport and Immunity Outline The Lymphatic System Lymph Vessels Lymphoid Organs Nonspecific Defenses Barriers Inflammatory Response Specific Defenses Antibodies T Cells Induced Immunity Active

More information

Chapter 17A: Adaptive Immunity Part I

Chapter 17A: Adaptive Immunity Part I Chapter 17A: Adaptive Immunity Part I 1. Overview of Adaptive Immunity 2. T and B Cell Production 3. Antigens & Antigen Presentation 4. Helper T cells 1. Overview of Adaptive Immunity The Nature of Adaptive

More information

ANATOMY OF THE IMMUNE SYSTEM THE IMMUNE SYSTEM. ANATOMY OF THE IMMUNE SYSTEM Thymus glandular organ near the heart where T cells learn their jobs

ANATOMY OF THE IMMUNE SYSTEM THE IMMUNE SYSTEM. ANATOMY OF THE IMMUNE SYSTEM Thymus glandular organ near the heart where T cells learn their jobs THE IMMUNE SYSTEM 1 ANATOMY OF THE IMMUNE SYSTEM 2 We all get sick sometimes...but then we get better. What happens when we get sick? Why do we get better? The immune system is localized in several parts

More information

Chapter 14: The Lymphatic System and Immunity

Chapter 14: The Lymphatic System and Immunity Chapter 14: The Lymphatic System and Immunity Major function of the Lymphatic System o Network of vessels that collect and carry excess fluid from interstitial spaces back to blood circulation o Organs

More information

Chapter 22: Lymphatic System and Immunity

Chapter 22: Lymphatic System and Immunity I. Lymphatic System A. Functions of the Lymphatic System - list and describe: 1. 2. 3. B. Lymphatic Vessels 1. What are lymphatic capillaries? 2. Lymphatic capillaries differ from blood capillaries in

More information

IMMUNOLOGY STRUCTURE AND FUNCTION OF IMMUNE SYSTEM

IMMUNOLOGY STRUCTURE AND FUNCTION OF IMMUNE SYSTEM 59 IMMUNOLOGY STRUCTURE AND FUNCTION OF IMMUNE SYSTEM 59.1 INTRODUCTION The immune system is engaged in a constant surveillance of the body for pathogens or tumors. Whether disease develops depends on

More information

MICROBIOLOGY - IMMUNOLOGY MODULE Dr Ronnie Russell

MICROBIOLOGY - IMMUNOLOGY MODULE Dr Ronnie Russell The Specific/Adaptive Immune Response The Third Line of Defence Is called specific immunity The body s ability to recognize and defend itself against distinct invaders and their products Is a smart system

More information

Basics of Immunology

Basics of Immunology Basics of Immunology 2 Basics of Immunology What is the immune system? Biological mechanism for identifying and destroying pathogens within a larger organism. Pathogens: agents that cause disease Bacteria,

More information

Types of Hypersensitivity. Type I: Allergic Reactions. more on Allergic Reactions

Types of Hypersensitivity. Type I: Allergic Reactions. more on Allergic Reactions Chapter 19: Disorders of the Immune System 1. Hypersensitivity 2. Autoimmunity 3. Transplant Rejection 1. Hypersensitivity What is Hypersensitivity? Hypersensitivity is an immunological state in which

More information

Test 4 Immune System (Chapters 20 & 21)

Test 4 Immune System (Chapters 20 & 21) Test 4 Immune System (Chapters 20 & 21) Name: Date: 1) The is the largest lymphoid organ. 1) A. lymph node B. spleen C. thymus D. tonsil 2) Tonsils promote memory of pathogens by. 2) A. secreting antibodies

More information

Immune System Part II: The Innate Immune System

Immune System Part II: The Innate Immune System Immune System Part II: The Innate Immune System Devastation Caused by Pathogens Influenza epidemic 1918-1919 Killed 22 million people in 18 months. Three million people will die from malaria this year.

More information

Immune System A&P II

Immune System A&P II Immune System A&P II Lymphatic Outline Lymphatic System Defense Systems Innate Immune System Adaptive Defense System Immunodeficiencies Immune Responses Lymphatic System: Overview Figure 21.1a, b Lymphatic

More information

The Lymphatic System

The Lymphatic System The Lymphatic System Transports escaped fluids back to the blood Plays essential roles in body defense and resistance to disease Lymph excess tissue fluid carried by lymphatic vessels Properties of lymphatic

More information

Page 1. Name: 1) The diagram below represents one possible immune response that can occur in the human body.

Page 1. Name: 1) The diagram below represents one possible immune response that can occur in the human body. Name: 8931-1 - Page 1 1) The diagram below represents one possible immune response that can occur in the human body. 5) One similarity between cell receptors and antibodies is that both A) are involved

More information

18 The Lymphatic System (Immune System) Nonspecific Resistance, Specific Immunity. Taft College Human Physiology

18 The Lymphatic System (Immune System) Nonspecific Resistance, Specific Immunity. Taft College Human Physiology 18 The Lymphatic System (Immune System) Nonspecific Resistance, Specific Immunity Taft College Human Physiology O 2 Diagram of Lymphatic and Cardiovascular Systems Lungs Heart Arteries w/ Plasma Arterioles

More information

Recognise phagocytes and lymphocytes under the light microscope;

Recognise phagocytes and lymphocytes under the light microscope; Immunity The immune system Vaccination Learning Objective Recognise phagocytes and lymphocytes under the light microscope; The following micrographs show as to how different types of phagocytes and lymphocytes

More information

Chapter 3. Immunity and how vaccines work

Chapter 3. Immunity and how vaccines work Chapter 3 Immunity and how vaccines work 3.1 Objectives: To understand and describe the immune system and how vaccines produce immunity To understand the differences between Passive and Active immunity

More information

The Humoral Immune system Structure and Diversity

The Humoral Immune system Structure and Diversity The Humoral Immune system Structure and Diversity Discussion: Introduction Our immune system protects our bodies from the harmful affects of a dizzying array of disease causing pathogens. Although our

More information

BIOLOGICAL SCIENCE CONCEPTS: BIO113 1

BIOLOGICAL SCIENCE CONCEPTS: BIO113 1 BIOLOGICAL SCIENCE CONCEPTS: BIO113 1 There are 4 portions of this review a list of objectives, a table of diseases, sample multiple choice questions, and general questions. Your notes are the most important

More information

Lymph capillaries, Lymphatic collecting vessels, Valves, Lymph Duct, Lymph node, Vein

Lymph capillaries, Lymphatic collecting vessels, Valves, Lymph Duct, Lymph node, Vein WLHS/A&P/Oppelt Name Lymphatic System Practice 1. Figure 12-1 provides an overview of the lymphatic vessels. First color code the following structures. Color code in Figure 12-1 Heart Veins Lymphatic vessels/lymph

More information

Overview of the Cattle Immune System 1

Overview of the Cattle Immune System 1 Oregon State University BEEF043 Beef Cattle Library Beef Cattle Sciences Overview of the Cattle Immune System 1 Reinaldo F. Cooke 2 Introduction On average, the U.S. cattle industry loses more than $1

More information

Immune System. Chapter 24

Immune System. Chapter 24 Immune System Chapter 24 Chapter Outline Immunology Lymphatic System Non-specific defense a. Defense at body surface b. Inflammation c. Phagocytosis macrophages, neutrophils d. Opsonins Ig and C 3 b e.

More information

Psychoneuroimmunology. Josée L. Jarry, Ph.D. Health Psychology, psy333 Department of Psychology University of Toronto September 30, 2002

Psychoneuroimmunology. Josée L. Jarry, Ph.D. Health Psychology, psy333 Department of Psychology University of Toronto September 30, 2002 Psychoneuroimmunology Josée L. Jarry, Ph.D. Health Psychology, psy333 Department of Psychology University of Toronto September 30, 2002 Psychoneuroimmunology - Definition The study of the link between

More information

T h. Immunity. Why? Model 1 Cell Mediated Response. How does our immune system protect us from disease?

T h. Immunity. Why? Model 1 Cell Mediated Response. How does our immune system protect us from disease? Why? Immunity How does our immune system protect us from disease? One way in which organisms maintain homeostasis is by detecting foreign cells and particles like pathogens and cancer cells. Once the pathogen

More information

Immunity. Humans have three types of immunity innate, adaptive, and passive: Innate Immunity

Immunity. Humans have three types of immunity innate, adaptive, and passive: Innate Immunity Immunity Humans have three types of immunity innate, adaptive, and passive: Innate Immunity Everyone is born with innate (or natural) immunity, a type of general protection. Many of the germs that affect

More information

CHAPTER 16: LYMPHATIC SYSTEM AND IMMUNITY OBJECTIVES. Transport excess tissue fluid back to blood stream

CHAPTER 16: LYMPHATIC SYSTEM AND IMMUNITY OBJECTIVES. Transport excess tissue fluid back to blood stream CHAPTER 16: LYMPHATIC SYSTEM AND IMMUNITY OBJECTIVES 1. Name the organs that compose the lymphatic system and give three general functions performed by this system. Control Disease Bone Marrow Thymus Transport

More information

Fundamental Immunology (Introduction to the Immune System) By. Faculty of Medicine, Suez canal University, Ismailia EGYPT

Fundamental Immunology (Introduction to the Immune System) By. Faculty of Medicine, Suez canal University, Ismailia EGYPT Fogarty-IBRO School Nairobi-KENYA May 22 nd 25 th 2007 Fundamental Immunology (Introduction to the Immune System) By Ahmed El-Gohary, M.D. Faculty of Medicine, Suez canal University, Ismailia EGYPT The

More information

Immuno-Oncology Therapies to Treat Lung Cancer

Immuno-Oncology Therapies to Treat Lung Cancer Immuno-Oncology Therapies to Treat Lung Cancer What you need to know ONCHQ14NP07519 Introduction: Immuno-oncology represents an innovative approach to cancer research that seeks to harness the body s own

More information

What is the lymphatic system and what are its functions? Detail the path followed by fluid entering lymphatic capillaries. What forces cause the

What is the lymphatic system and what are its functions? Detail the path followed by fluid entering lymphatic capillaries. What forces cause the 2. 2. 2. 3. 4. 5. 6. 7. 8. 9. 10. 1 12. 13. 14. 15. What is the lymphatic system and what are its functions? Detail the path followed by fluid entering lymphatic capillaries. What forces cause the fluid

More information

The Lymphatic System and Body Defenses The Lymphatic System Consists of two semi-independent parts Lymphatic vessels Lymphoid tissues and organs

The Lymphatic System and Body Defenses The Lymphatic System Consists of two semi-independent parts Lymphatic vessels Lymphoid tissues and organs The Lymphatic System and Body Defenses The Lymphatic System Consists of two semi-independent parts Lymphatic vessels Lymphoid tissues and organs Lymphatic system functions Transports escaped fluids back

More information

22. Immune System and the Body s Defense

22. Immune System and the Body s Defense 22. Immune System and the Body s Defense I. Overview of Diseases Caused by Infectious Agents Disease can be caused by a variety of factors, some have causes within our bodies (e.g., genetic disorders and

More information

The Lymphatic System and Body Defenses

The Lymphatic System and Body Defenses o The Lymphatic System and Body Defenses Lymphatic system Anatomy Non specific defenses o The Lymphatic System Consists of two semi-independent parts Lymphatic vessels Lymphoid tissues and organs Lymphatic

More information

Core Topic 2. The immune system and how vaccines work

Core Topic 2. The immune system and how vaccines work Core Topic 2 The immune system and how vaccines work Learning outcome To be able to describe in outline the immune system and how vaccines work in individuals and populations Learning objectives Explain

More information

GRADE 8 STUDY PACKET IMMUNE SYSTEM SC.6.L.14.5 AA

GRADE 8 STUDY PACKET IMMUNE SYSTEM SC.6.L.14.5 AA GRADE 8 STUDY PACKET IMMUNE SYSTEM SC.6.L.14.5 AA SC.6.L.14.5 AA Identify and investigate the general functions of the major systems of the human body (digestive, respiratory, circulatory, reproductive,

More information

BLOOD GROUPS AND IMMUNOGENETICS

BLOOD GROUPS AND IMMUNOGENETICS BLOOD GROUPS AND IMMUNOGENETICS Knowledge of human blood types is necessary for successful transfusions. Recognition that blood types have relatively simple inheritance patterns led to their use in paternity

More information

Chapter 43: Immune System

Chapter 43: Immune System AP Biology Reading Guide Fred and Theresa Holtzclaw Julia Keller 12d Chapter 43: Immune System 1. Briefly explain the six steps to ingestion and destruction of a microbe by a phagocytic cell. First, pseudopodia

More information

The Immune System. How your immune system works. Organs of the Immune System

The Immune System. How your immune system works. Organs of the Immune System UW MEDICINE PATIENT EDUCATION The Immune System How your immune system works The immune system is a network of special cells, tissues, and organs that defend the body against attacks from foreign invaders,

More information

Name Date Class. This section explains what kinds of organisms cause infectious disease and how infectious diseases are spread.

Name Date Class. This section explains what kinds of organisms cause infectious disease and how infectious diseases are spread. Fighting Disease Name Date Class Infectious Disease This section explains what kinds of organisms cause infectious disease and how infectious diseases are spread. Use Target Reading Skills Before you read,

More information

Welcome to Mini Med School at the Child & Family Research Institute

Welcome to Mini Med School at the Child & Family Research Institute Glossary Welcome to Mini Med School at the Child & Family Research Institute On behalf of the Faculty and Staff at the Child & Family Research Institute (CFRI), we would like to welcome you to CFRI s

More information

Innate Host Defenses Graphics are used with permission of Pearson Education Inc., publishing as Benjamin Cummings (http://www.aw-bc.com).

Innate Host Defenses Graphics are used with permission of Pearson Education Inc., publishing as Benjamin Cummings (http://www.aw-bc.com). Innate Host Defenses Graphics are used with permission of Pearson Education Inc., publishing as Benjamin Cummings (http://www.aw-bc.com). Page 1: Introduction Surface barriers (the skin, mucous membranes,

More information

Mosby s PATHOLOGY for Massage Therapists. Lesson 9.1 Objectives. Chapter 9 Lymphatic and Immune Pathologies. Lymphatic System Overview

Mosby s PATHOLOGY for Massage Therapists. Lesson 9.1 Objectives. Chapter 9 Lymphatic and Immune Pathologies. Lymphatic System Overview Mosby s PATHOLOGY for Massage Therapists Chapter 9 Lymphatic and Immune Pathologies Lesson 9.1 Objectives Discuss anatomic structures and physiologic processes related to the lymphatic system. Describe

More information

Single-celled microorganisms, which can live inside or outside the body. Some cause sickness, but others are harmless.

Single-celled microorganisms, which can live inside or outside the body. Some cause sickness, but others are harmless. The Science behind the Noses are Red show: Introduction: The Noses are Red show is about allergies and the biological causes behind them. In order to explain allergies you need to understand a certain

More information

AN OVERVIEW OF THE IMMUNE SYSTEM. Abbas et al. 4th ed. Chapter 1; Janeway et al., 5th ed. Chapter 1.

AN OVERVIEW OF THE IMMUNE SYSTEM. Abbas et al. 4th ed. Chapter 1; Janeway et al., 5th ed. Chapter 1. Harvard-MIT Division of Health Sciences and Technology HST.176: Cellular and Molecular Immunology Course Director: Dr. Shiv Pillai Recommended reading AN OVERVIEW OF THE IMMUNE SYSTEM Abbas et al. 4th

More information

Chapter 43: The Immune System

Chapter 43: The Immune System Name Period Our students consider this chapter to be a particularly challenging and important one. Expect to work your way slowly through the first three concepts. Take particular care with Concepts 43.2

More information

Candy Antigens and Antibodies

Candy Antigens and Antibodies LAB ACTIVITY: Candy Antigens and Antibodies TEACHER S EDITION Curricular Links: Biology 20, Science 30 Class Time: 1 period Suggested Answers: Question 1: What is the main function of red blood cells?

More information

M I C R O B I O L O G Y WITH DISEASES BY TAXONOMY, THIRD EDITION

M I C R O B I O L O G Y WITH DISEASES BY TAXONOMY, THIRD EDITION M I C R O B I O L O G Y WITH DISEASES BY TAXONOMY, THIRD EDITION Chapter 18 Other Immune Disorders Lecture prepared by Mindy Miller-Kittrell, University of Tennessee, Knoxville Hypersensitivities Hypersensitivity

More information

Understanding How Existing and Emerging MS Therapies Work

Understanding How Existing and Emerging MS Therapies Work Understanding How Existing and Emerging MS Therapies Work This is a promising and hopeful time in the field of multiple sclerosis (MS). Many new and different therapies are nearing the final stages of

More information

MISSION DEBRIEFING: Teacher Guide

MISSION DEBRIEFING: Teacher Guide Activity on the IMMUNE SYSTEM: The Body Fights Back In this activity, the students will use a hands-on approach to learn about the immune system and how it fights off pathogens that invade the body. They

More information

What Causes Infectious Diseases. Chapter 28 Lesson 1

What Causes Infectious Diseases. Chapter 28 Lesson 1 What Causes Infectious Diseases Chapter 28 Lesson 1 Causes of Infectious Diseases Every infectious disease is caused by one of several types of small, microscopic organisms called pathogens. Most pathogens

More information

Chapter 16: Innate Immunity

Chapter 16: Innate Immunity Chapter 16: Innate Immunity 1. Overview of Innate Immunity 2. Inflammation & Phagocytosis 3. Antimicrobial Substances 1. Overview of Innate Immunity The Body s Defenses The body has 2 types of defense

More information

ME 411 / ME 511. Biological Frameworks for Engineers

ME 411 / ME 511. Biological Frameworks for Engineers ME 411 / ME 511 Biological Frameworks for Engineers Class Organization Lab 1 due today Hw 3 due on Friday Lab 2 Lab-on-a-Chip Fri, More 320 Sign up for 2:00-3:15, 3:15-4:30 slots Read the pre-lab instructions

More information

B Cells and Antibodies

B Cells and Antibodies B Cells and Antibodies Andrew Lichtman, MD PhD Brigham and Women's Hospital Harvard Medical School Lecture outline Functions of antibodies B cell activation; the role of helper T cells in antibody production

More information

Immune system. B cells and T cells. B cells and T cells. Immunoglobulins. Immunoglobulins. Immunoglobulins (antibodies) stem cell

Immune system. B cells and T cells. B cells and T cells. Immunoglobulins. Immunoglobulins. Immunoglobulins (antibodies) stem cell Immune system - many different types of cells mediate the to destroy bacteria and viruses as well as pre-cancerous cells - all cells in the immune system, as well as all the red blood cells, arise from

More information

The Circulatory System. Chapter 17 Lesson 1

The Circulatory System. Chapter 17 Lesson 1 The Circulatory System Chapter 17 Lesson 1 Functions of the Circulatory System Your circulatory system maintains an internal environment in which all the cells in your body are nourished. As your heart

More information

Species at war. Information sheets and question sheets. Science: Biology. Microorganisms, pathogens and the body s defences.

Species at war. Information sheets and question sheets. Science: Biology. Microorganisms, pathogens and the body s defences. Species at war Information sheets and question sheets Subject(s): Science: Biology Age group(s): 12 14 Topic(s): Microorganisms, pathogens and the body s defences Source This resource was originally developed

More information

HUMORAL IMMUNE RE- SPONSES: ACTIVATION OF B CELLS AND ANTIBODIES JASON CYSTER SECTION 13

HUMORAL IMMUNE RE- SPONSES: ACTIVATION OF B CELLS AND ANTIBODIES JASON CYSTER SECTION 13 SECTION 13 HUMORAL IMMUNE RE- SPONSES: ACTIVATION OF B CELLS AND ANTIBODIES CONTACT INFORMATION Jason Cyster, PhD (Email) READING Basic Immunology: Functions and Disorders of the Immune System. Abbas,

More information

If you have a cold or the flu, you can spread the sickness to someone else. How does the sickness spread? Write your ideas on the lines below.

If you have a cold or the flu, you can spread the sickness to someone else. How does the sickness spread? Write your ideas on the lines below. The Immune System Textbook pages 100 109 Before You Read Section 3.1 Summary If you have a cold or the flu, you can spread the sickness to someone else. How does the sickness spread? Write your ideas on

More information

Viral Attack! Your Clean-Up Crew to the Rescue! A Gallery Demonstration at Arizona Science Center

Viral Attack! Your Clean-Up Crew to the Rescue! A Gallery Demonstration at Arizona Science Center Viral Attack! Your Clean-Up Crew to the Rescue! A Gallery Demonstration at Arizona Science Center Table of Contents Background Information Links Background Information What is the immune system? Our body

More information

FIGHTING AIDS AT THE GATE

FIGHTING AIDS AT THE GATE FIGHTING AIDS AT THE GATE T h e r a m p a n t s p r e a d o f H I V i n f e c t i o n a c r o s s t h e g l o b e i s n o l o n g e r t h e m e d i a c r i s i s o f t h e m o m e n t. B u t A I D S h

More information

Clinical Manifestations of Adverse Reactions. Definitions and Classifications. Exaggerated Effect on Target Tissues

Clinical Manifestations of Adverse Reactions. Definitions and Classifications. Exaggerated Effect on Target Tissues Chapter 3 Outline Chapter 3: Adverse reactions Definitions and classifications Clinical manifestations of adverse reactions Toxicologic evaluation of drugs 2 Haveles (p. 28) Drugs may act on biologic systems

More information

Microbiology 532 Immunology Examination KEY October 30, 2003

Microbiology 532 Immunology Examination KEY October 30, 2003 KEY October 30, 2003 All questions have equal point value. You may keep the test questions. Multiple Choice (choose the best answer) 1. Receptors associated with innate immunity recognize microbes by detecting:

More information

SYSTEM Teacher Pages THE IMMUNE. Your students will learn:

SYSTEM Teacher Pages THE IMMUNE. Your students will learn: Grade Level 3-5 Sergeant Cell s Immune System Defense Team Webquest Activity Summary Comparing immune cells with a police team, the webquest activity guides students to research the immune system online.

More information

37 2 Blood and the Lymphatic System Slide 1 of 34

37 2 Blood and the Lymphatic System Slide 1 of 34 1 of 34 Blood is a connective tissue that contains both dissolved substances and specialized cells. 2 of 34 The functions of blood include: collecting oxygen from the lungs, nutrients from the digestive

More information