Project Management in Large-Scale Research Projects

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1 Project Management in Large-Scale Research Projects Robyn Roscoe, BSc, PMP Head, Strategic Planning and Project Management BC Cancer Agency Genome Sciences Centre

2 BC Cancer Agency Genome Sciences Centre Started in 1999 by Dr. Michael Smith Canada s largest genome centre, ~5 th largest in the world ~280 staff, including 9 faculty, 14 staff scientists, and over 60 trainees Operates at 2 locations over 50,000 sq. ft. of lab and office space Part of British Columbia Cancer Agency, part of Provincial Health Service Authority (PHSA) BC Cancer Agency Branch

3 Total Funding 1999-Present $487,461,059 total 256 grants/contracts MSFHR; 3% NSERC; 1% CIHR; 7% CFI; 14% CCSRI; 3% Cdn Other; 3% USDOD; <1% NIH; 29% GC/GBC; 40% US Other; <1% GSC Grant Application Success Rate (1999-present): 45% BC Cancer Agency Branch

4 Funding sources Grants, contracts, collaborations GSC BC Cancer Agency Branch

5 Mangage-ome TM Marco Marra, PhD Director Operations Team Leader Letticia Kwong, MSc Projects Team Leader Robyn Roscoe, BSc, PMP Finance Team Leader Laura Barraotevana Human Resources Marilyn Gillespie, CHRP Laboratory Operations Lorraine May George Yang Ruth Appanah Paul Lythgo Purchasing Group (3.5 FTE) Project Managers Joanne Johnson, PhD, PMP Adrienne Drobnies, PhD, PMP Armelle Troussard, PhD Cynthia Ferguson, BSc, PMP Diane Miller, MSc, PMP Dominik Stoll, PhD, PMP Karen Novik, PhD Stephanie McInnis, PhD Russ Watkins, PhD Anita Charters, MA, PMP Finance Associates Rodney Chin, CGA Monica Cornean Jennifer Hardie BC Cancer Agency Branch 2010 Admin team (5 FTE) Project Coordinators Becky Gillespie Julia Chae Mhairi Sigrist, PhD 5

6 Rationale for Project Management Sound project management adds value and increases successful project outcomes. Focusing appropriate expertise on the management or business of the project and allows the scientists to focus on the science. Fostering culture of project management within the research team leads to scope and budget control throughout the project. BC Cancer Agency Branch

7 Role of the Project Manager Manage project communications Granting agencies Collaborators/clients Monitor and manage project progress Milestone or objective management Contingency planning Maintain control budget and scope Facilitate grant applications and submissions BC Cancer Agency Branch

8 Best project management software Team of project managers! BC Cancer Agency Branch 2010

9 Manage Communications Internal: PI and project team, department/institution External: Funders, Regulators, Public Communication tools , meeting Reports progress, status, forecast BC Cancer Agency Branch

10 Monitor Progress Reports Gantt charts Financial status Reports progress, status, forecast Meetings Project wiki BC Cancer Agency Branch

11 Maintain Control Control does not mean limit or restrict it means check and correct as required Within funder rules and guidelines Emphasis on scope management Stamp out Scope Creep! Challenge: science is all about change BC Cancer Agency Branch

12 SCOPE CREEP BC Cancer Agency Branch

13 SCOPE CHANGE BC Cancer Agency Branch

14 Disrup've next genera'on sequencing technology > 2,800 fold decrease in cost / base >4,600- fold increase in throughput / instrument- year Old Generation (pre-2006) Next Generation ( ) = 92 machine- years BC Cancer Agency Branch machine- week 14

15 Evolution of the Next-generation Sequencing Platform at the GSC GA-IIx released Illumina GAs 2 cluster stations PET in development Standard read length 35bp Flow cell raw data yield 3.5Gbps or 10.5Gbps/week 16 Illumina GAiix s 8 cluster stations PET standard on all instruments Read lengths up to 100bp Flow cell raw data yield 50Gbps or 700 Gbps/week 10 SOLiD version 4.0 sequencers - >460Gbps/week September 2007 to September 2010 BC Cancer Agency Branch

16 The Illumina HiSeq 2000 BC Cancer Agency Branch

17 Evolution of disruption 1E+10 Cost 1E pre BC Cancer Agency Branch

18 Facilitate grant applications Identify funding opportunities Review research ideas Grant writing and submission Connect with others Statistical analysis Protocol design Bioinformatics REB and other certification BC Cancer Agency Branch

19 Role of the Project Manager Listen, remind, encourage , spreadsheets (repeat as needed) Challenging Keeping science organized Keeping up with changing technology Meeting funder requirements Allow scope change while preventing scope creep Contribution enabling research BC Cancer Agency Branch

20 Rationale for Project Management in Research Project and business management expertise improves research outcomes Scientific resources focus scientific activities greater scientific success Management professionals provision of higher quality service Integration of PMt principles throughout project teams efficient successful projects BC Cancer Agency Branch

21 BC Cancer Agency Branch 2010

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