2nd Course on Breast Cancers : February Programme Training Unit - International Course - Open conferences (in blue)

Transcription

1 2nd Course on Breast Cancers : February Programme Training Unit - International Course - Open conferences (in blue) Monday February 14th Chair : Jean Yves Pierga 02/02/ :30-09:00 Welcome and coffee "Joliot room" 09:30 Jean Yves Pierga Presentation of the module 09:30- Students presentation/ personal work Short presentation of background and research interest (1 mn each) - 11:15 11:15-11:45 11:45-12:30 Anne Vincent-Salomon Bernard Asselain Normal histology of mammary gland & breast cancers classification Epidemiology 12:30-13:15 13:15 Anne Tardivon LUNCH "salle Joliot" and poster set up From basic to advanced imaging 14:15- Fabien Reyal Surgery 15:45 15:45-16:15 Jorge Reis-Filho (ICR, London, UK) Molecular classification of breast cancers 16:15- Alain Fourquet Multidisciplinary treatment of breast cancer - 17:45 Véronique Diéras Cytotoxic chemotherapy and targeted therapies for breast cancer 17:45-18:15 Discussion 18:30 Welcome party, "Chez Marie" room 12, rue Lhomond Paris

2 Tuesday February 15th Chair : Anne Vincent-Salomon 09: :00 Dominique Stoppa-Lyonnet Marc-Henri Stern High susceptibility genes and management of a risk woman Molecular Characterization of BRCA1 tumors 11: :30 12:30-14:15-15:30 15:30-16:00 16:00-16:30 16: :45 Alan Ashworth (ICR, London, UK) Targeted therapy for basal-like cancers Presentation by Michel Wassef Iorns E et al, Cancer Cell 2008 vol 13; pages Presentation by Tomasz Zaremba Silver D et al, JCO 2010 vol 28; pages Peter Campbell (Welcome Trust Sanger Institute, Cambridge, UK) NGS in breast cancers Presentation by Cristovao Sousa Ding et al, Nature 2010, vol 464; pages Presentation by Guillaume Rieunier Feng Z et al, PNAS 2011, vol 108; pages Presentation by Karla Perez Toralla Moskwa P et al, Molecular Cell 2011; Vol 41; pages 1-11 Janet Hall (Institut Curie, Orsay, France) Radiobiology in breast cancers Amphithéâtre Lacassagne 22, rue d'ulm (allée à droite du n 26) 17:45 Discussions

3 Wednesday February 16th Chair : Jean Yves Pierga Geneviève Almouzni (UMR 218, Institut Curie/CNRS Paris, France) Epigenetic mechanisms in oncogenesis - 10:15 10:15-10:45 10:45-11:15 11: :30 12:30- Presentation by Sardar Faisal Mahmood Groth A et al, Science 2007; vol 318; pages Presentation by Arnaud Gauthier Corpet A et al, EMBO Mol Med 2010; PMID: Stephan Vagner (Institut Gustave Roussy, Villejuif, France) mirna regulation Presentation by Franck Bielle Tavazoie S et al, NATURE 2008, vol 451; pages Presentation by Christophe Couderc Mayr C et al, CELL 2009, vol 138; pages :00-19:00 FREE AFTERNOON

4 Thursday February 17th Chair: Fatima Mechta-Grigoriou 02/02/ Emmanuelle Charafe-Jauffret (IP Calmette, Marseille, France) Robert Clarke (Paterson Institute for Cancer Research, Manchester, UK) Stem cells in breast cancer Stem cell and models - 11:00 11:00-11:30 11:30- Presentation by Marcello Albanesi Liu H et al, PNAS 2010, vol 107; pages Presentation by Angie Molina Lim E et al, NATURE MEDICINE 2009, vol 15; pages Jos Jonkers (The Netherlands Cancer Institute, Amsterdam) Targeting DNA repair defects in conditional mouse models of breast cancers 14:00-14:30 14:30-15:45 15:45-16:15 Presentation by Duncan Sproul Pece S et al, CELL 2010, vol 140; pages Presentation by Luiza Stankevicins Derksen P et al, CANCER CELL 2006, vol 10; pages Marina Glukhova BREAK "Joliot Room" Transgenic mouse models of breast cancer 16:15- Elisabetta Marangoni Patient's derived breast cancer xenografts - 17:30 17:30-18:00 Presentation by Joanna Moes-Sosnowska Liu X et al, PNAS 2007, vol 104 pages Presentation by Laetitia Kasprzyk de Plater L et al, BRITISH JOURNAL OF CANCER 2010, vol 103(8); pages :00 Discussion

5 Friday February 18th Chair : Olivier Delattre Fatima Mechta Grigoriou Role of stroma in breast cancer :00 11:00-11:30 Richard Iggo (Institut Bergonié, Bordeaux, France) Presentation by Daniel Lafkas Transcriptomic analysis of stroma in breast cancer Toullec A et al, EMBO Molecular Medicine 2010, vol 2 June. 11: :00-14:30 Presentation by Mara Artibani Finak G et al, NATURE MEDICINE 2008, vol 14; pages Jean-Yves Pierga Bone marrow micrometastases and circulating cells in breast cancer: a new prognosis marker? Presentation by Dieter Peeters Punnoose E et al, PLOS One 2010, vol 5; pages E :30- Presentation by Stanislas du Manoir Andreu P et al, CANCER CELL 2010, vol 17; pages :45 15:45-16:15 Lisa Coussens (UCSF, San Francisco, CA, USA) Inflammation & Cancer : reprogramming immune response as an anti-cancer strategy 16: :30 Gordon Tucker (Institut Servier, Neuilly, France) Research in industry Presentation by Elsa Curtit Denardo D et al, CANCER CELL 2009, vol 16; pages :30-18:15 Julie Sappa (Alex Edelman et Associates, Malakoff, France) To write a paper 19:00 Farewell Cocktail & Buffet Dinner "Chez Marie" room 12, rue Lhomond Paris

6 Saturday February 19th Chair : Anne Vincent-Salomon - 10:15 10:15-10:45 10:45-11:15 11:15- - Brigitte Sigal Clinical trials: conception and practical issues Presentation by Chloé Tessereau Bianchini G et al, CANCER RESEARCH 2010, vol 70; pages Presentation by Morgane Thion Von Hoff D et al, JCO 2010, vol 28; pages Fabrice André (Institut Gustave Roussy, Villejuif, France) All Towards a tailored treatment, a global view of the present and the future Closing remarks END OF COURSE