Magnetic Resonance Techniques in Neurodegenerative Diseases First Course Alzheimer s disease and frontotemporal lobar degeneration spectrum
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1 Università Vita-Salute San Raffaele Neuroimaging Research Unit Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute and Vita-Salute San Raffaele University Magnetic Resonance Techniques in Neurodegenerative Diseases First Course Alzheimer s disease and frontotemporal lobar degeneration spectrum SCIENTIFIC PROGRAM CME ACCREDITED COURSE San Raffaele Scientific Institute
2 ORGANIZING SECRETARIAT Biomedia srl Silvia Terragni Via L. Temolo Milano Tel. 02/ Fax 02/ silvia.terragni@biomedia.net Biomedia utilizza un Sistema di Gestione Qualità Certificato per progettazione ed erogazione di eventi di formazione residenziale e a distanza e di servizi organizzativi per corsi e convegni
3 MAGNETIC RESONANCE TECHNIQUES IN NEURODEGENERATIVE DISEASES First Course Alzheimer s disease and frontotemporal lobar degeneration spectrum SCIENTIFIC DIRECTION: M. Filippi A. Falini G. Comi SCIENTIFIC SECRETARIAT: F. Agosta G. Magnani ORGANIZING SECRETARIAT: G. Nyitrai L. Zonca FACULTY MEMBERS F. Agosta (Milan, Italy) P. Bosco (Brescia, Italy) C. Caltagirone (Rome, Italy) E. Canu (Milan, Italy) S. F. Cappa (Milan, Italy) G. Chetelat (Caen, France) G. Comi (Milan, Italy) B. Dubois (Paris, France) A. Falini (Milan, Italy) M. Filippi (Milan, Italy) N. Fox (London, UK) K. A. Josephs (Rochester, MN, USA) E. Karran (Cambridge, UK) D. M. Mann (Manchester, UK) M. Musicco (Rome, Italy) P. Nestor (Magdeburg, Germany) A. Padovani (Brescia, Italy) J. D. Rohrer (London, UK) F. Valtorta (Milan, Italy) B. N. Van Berckel (Amsterdam, NL) M. P. Wattjes (Amsterdam, NL) 1
4 Monday, 25 November Welcome and program overview G. Comi (Milan, Italy), M. Filippi (Milan, Italy), A. Falini (Milan, Italy) THE AMYLOID CASCADE AND ALZHEIMER S DISEASE: HYPOTHESIS OR THEORY? SESSION I CHANGING DIAGNOSTIC CONCEPTS OF ALZHEIMER S DISEASE I: GENETICS AND CLINICAL FEATURES Chairs: G. Comi (Milan, Italy), F. Valtorta (Milan, Italy) The genetics of Alzheimer s disease E. Karran (Cambridge, UK) The new lexicon for Alzheimer's disease B. Dubois (Paris, France), M. Musicco (Rome, Italy) Coffee break SESSION II CHANGING DIAGNOSTIC CONCEPTS OF ALZHEIMER S DISEASE II: NEUROIMAGING Chairs: M. Filippi (Milan, Italy), D. M. Mann (Manchester, UK) Amyloid imaging: diagnostic paradigm shift or limited clinical role? B. N. Van Berckel (Amsterdam, NL) Alzheimer s disease pattern of atrophy measures in clinical practice A. Falini (Milan, Italy) Advanced MR techniques to study neurodegeneration in Alzheimer s disease E. Canu (Milan, Italy) Lunch 2
5 Monday, 25 November MECHANISMS OF NEURODEGENERATION IN FTLD: THE RELEVANCE OF HUMAN CORTICAL CONNECTIVITY SESSION III UNRAVELLING FTLD: LESSONS FROM COGNITIVE NEUROSCIENCE, PATHOLOGY AND GENETICS Chairs: N. Fox (London, UK), K. A. Josephs (Rochester, MN, USA) Behavioural profile and language deficits in FTLD spectrum S. F. Cappa (Milan, Italy) Neuropathological and genetic heterogeneity of FTLD D. M. Mann (Manchester, UK) FTLD pathology targets large-scale human brain networks J. D. Rohrer (London, UK) Afternoon tea SESSION IV ASSESSING NEURODEGENERATION USING BRAIN NETWORK ANALYSIS IN FTLD SYNDROMES Chairs: J. D. Rohrer (London, UK), M. P. Wattjes (Amsterdam, NL) Structural brain connectivity in FTLD P. Nestor (Magdeburg, Germany) Functional brain connectivity in FTLD F. Agosta (Milan, Italy) Discussion 3
6 Tuesday, 26 November THE MISSING TARGETS IN DEMENTIA PREVENTION SESSION V CAN WE PREVENT DEMENTIA? IMAGING BIOMARKERS FOR CLINICAL TRIALS IN EARLY DEMENTIA Chairs: C. Caltagirone (Rome, Italy), P. Nestor (Magdeburg, Germany) Wet biomarkers A. Padovani (Brescia, Italy) Imaging of dementia: moving towards prevention N. Fox (London, UK) MR biomarkers for subject selection and monitoring treatment effects in Alzheimer s disease trials M. P. Wattjes (Amsterdam, NL) Infrastructures to foster drug discovery and monitoring in Alzheimer s disease P. Bosco (Brescia, Italy) Coffee break MR biomarkers as risk-detectors for Alzheimer s disease in cognitively normal individuals G. Chetelat (Caen, France) Imaging biomarkers for clinical trials in FTLD K. A. Josephs (Rochester, MN, USA) MR techniques in Alzheimer s disease and FTLD: where we are, what we need and where we are going M. Filippi (Milan, Italy) Concluding remarks G. Comi (Milan, Italy) Farewell cocktail 4
7 General Information REGISTRATION Registration is free and includes admission to scientific sessions, conference materials, coffee breaks, lunch and certificate of attendance. HOW TO REGISTER All participants are kindly recommended to register via the online registration form at CONTINUING MEDICAL EDUCATION (ECM only for Italian participants) The event addresses to the disciplines of Neurology, Neurophysiopathology, Neuroradiology. In order to obtain credits, participants must attend the full educational programme (100% of the meeting) and pass the final learning test available on line on the site CERTIFICATE OF ATTENDANCE A certificate of attendance will be available to each participant at the end of the meeting OFFICIAL LANGUAGE English. Simultaneous translation service is not provided. HOTEL ACCOMMODATION In case of accomodation please contact: Biomedia Travel di Biomedia srl Via L. Temolo, Milano Tel.: 02/ Fax: 02/ biomediatravel@biomedia.net CONGRESS VENUE San Raffaele Scientific Institute - Aula Caravella Pinta Via Olgettina, Milano, Italy HOW TO REACH THE VENUE Motorways: San Raffaele Congress Centre can be reached by all motorways, following the direction "Tangenziale Est" (East ring road) till Cascina Gobba exit. Subway: San Raffaele Congress Centre is connected to Milan by green subway line. The subway stop is Cascina Gobba. Railway: Milano Central Railway Station is connected to San Raffaele Congress Centre by subway (green line). Airports: Malpensa Airport (50 km) and Linate Airport (5km) are connected to San Raffaele Congress Centre by railway, bus or taxi. 5
8 Magnetic Resonance Techniques in Neurodegenerative Diseases First Course Alzheimer s disease and frontotemporal lobar degeneration spectrum Unrestricted Educational Grant from Novartis
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