The bottom line: CorCell offers you peace of mind.

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2 Dear Expectant Parents, Thank you for your interest in CorCell and congratulations on the impending birth of your child. The day your child is born is a momentous occasion. And saving your baby s cord blood can help protect his or her health in the years to come. It s important to remember that the opportunity to collect and preserve your baby s umbilical cord blood only comes once in a lifetime. If cord blood is not collected at birth and preserved, this irreplaceable source of stem cells is lost forever. These regenerative cells may help your baby combat life-threatening illness. CorCell is the trusted cord blood banking company for new parents. We ve been banking baby s cord blood for more than 15 years and go through the most rigorous procedures in the industry to help protect your family s stem cells. The bottom line: CorCell offers you peace of mind. This booklet should answer most of your questions about CorCell and cord blood banking and includes everything you need to enroll. You can find even more information at corcell.com or by calling our 24-hour customer care center at (888) with any questions. Or text CorCell to and a representative will call you immediately. Congratulations again on taking this first step toward helping secure your baby s tomorrow. Best wishes to you and your family s future, Joseph Vicente President, CorCell Companies, Inc.

3 As you prepare for your newborn s arrival, protecting his health is among your top concerns. Preserving his cord blood is an important step for securing future well-being. The five minutes it takes to save your child s cord blood cells could prove to be a once in a lifetime opportunity to retain this protection. Collecting cord blood is painless and safe for mother and baby. When you choose CorCell, your baby s umbilical cord blood is being collected and preserved the right way, every step of the way. So it s easy for you, your doctor and the hospital. Banking cord blood helps protect your child s future health Cord blood stem cells, a life-saving resource for disease treatment Stem cells from cord blood, like bone marrow cells, are now being used to successfully treat more than 70 diseases including leukemia, anemia, non-hodgkin s lymphoma, many other cancers, and impaired immune systems. Researchers are encouraged by the potential of rapidly expanding medical applications utilizing cord blood stem cells. Your baby s own stem cells Umbilical cord blood contains stem cells. While it s something no new parent wants to think about, if your child should ever need a stem cell transplant, his very own match will be on reserve when you bank this cord blood. Treatment time is faster and there are no rejection issues dramatically increasing the chances of a successful transplant. Our son Jake was born with Bladder Extrophy, a rare birth defect. In the future Jake s stem cells may be able to be used for reconstructive repair to grow his own tissue, something his body won t reject because it is his own. This could mean a world of difference for the quality of life our son will have, and for that I am eternally grateful that we took the step to save his cord blood with CorCell. Sandra Gallagher-Mohler Maryland A potential match for another family member Although not always a perfect match, banked stem cells could potentially be used to treat siblings or other blood relatives should there be a close match. CorCell.com (888)

4 Why Cord Blood Banking

5 Umbilical cord blood has been used as an alternative source of hematopoietic stem cells for the treatment of human disease since The cumulative probability that a person will have some type of stem cell transplant by age 70, either from their own cells or from a donor, is approximately 1 in 200.* Cord blood stem cells save lives Cord blood stem cells hold amazing promise for the future. Researchers are encouraged by the rapidly expanding potential of medical applications utilizing cord blood stem cells. Today there are more than 10,000 stem cell clinical trials occurring around the world to address pervasive conditions such as cerebral palsy, heart disease, diabetes, lung disease, liver disease, lupus, Alzheimer s disease, multiple sclerosis, muscular dystrophy, Parkinson s disease, rheumatoid arthritis, spinal cord injury, stroke and more. CorCell is the choice for families desiring both treatment options now and in the future. Unlike other companies our cord blood samples are processed utilizing the technology required to take advantage of impending cellular therapies. My mom was dying of ovarian cancer and decided that saving her grandchild s umbilical cord blood would be her gift to him. Since there is familial history of blood-related and other cancers in both mine and my husband s families, we decided to save all of our children s umbilical cord bloods. Maria Ydrach Puerto Rico CorCell.com For extensive information on CorCell s unique advantages, the collection and storage process, medical benefits of cord blood banking, insurance partners and more, visit corcell.com * SOURCE: Nietfeld, JJ et al., Biol. Blood and Marrow Trans. 2008;14: CorCell.com (888)

6 Medical Benefits

7 Here is just a partial listing of diseases now being treated through cord blood stem cell transplants. And future medical advancements will create unforeseen treatment opportunities in the years to come. CorCell collects and stores your baby s cord blood with tomorrow s treatments in mind. By 2015 the National Marrow Donor Program anticipates facilitating 10,000 stem cell transplants per year * Leukemias and Lymphomas Acute Lymphoblastic Leukemia (ALL) Acute Myelogenous Leukemia (AML) Chronic Myelogenous Leukemia (CML) Chronic Lymphocytic Leukemia (CLL) Juvenile Chronic Myelogenous Leukemia Juvenile Myelomonocytic Leukemia Chronic Myelomonocytic Leukemia (CMML) Stem Cell Disorders Aplastic Anemia (Severe) Fanconi Anemia Paroxysmal Nocturnal Leukemia (CMML) Pure Red Cell Aplasia Myeloproliferative / Lymphoproliferative Disorders Acute Myelofibrosis Non-Hodgkin s Lymphoma Hodgkin s Disease Phagocyte Disorders Inherited Platelet Abnormalities Inherited Metabolic Disorders Hurler s Syndrome (MPS-IH) Hunter s Syndrome (MPS-II) Mucolipidosis II (I-cell Disease) Krabbe Disease Gaucher s Disease Tay-Sachs Plasma Cell Disorders Multiple Myeloma Other Inherited Disorders and Abnormalities Sickle Cell Disease Osteoporosis Other Malignancies Ewing Sarcoma Neuroblastoma Renal Cell Carcinoma Retinoblastoma Potential Future Applications Currently In Research Alzheimer s Disease Cerebral Palsy Diabetes Epidermolysis Bullosa Heart Disease Lupus Multiple Sclerosis Muscular Dystrophy Parkinson s Disease Rheumatoid Arthritis Spinal Cord Injury Stroke ALS/Lou Gehrig s Disease Huntington s disease For a more detailed list and information about diseases treated, visit I was born with a fatal blood disorder called Fanconi Anemia. My sister Emily s cord blood saved my life when it was used for a transplant in Natalie Curry New York * SOURCE: National Marrow Donor Program, 2009 Report to the Community CorCell.com (888)

8 A Stem Cell Leader

9 From collection to processing to storage and to retrieval for transplant, CorCell s process is unparalleled. Our state-of-the art facilities, experienced professionals, proprietary processes that exceed government standards, and future-oriented philosophy ensures that your child s cord blood is in the safest hands possible and prepped for use in forthcoming therapies we can t even imagine today. You can feel confident with CorCell, a leader in cord blood collection and storage Headquartered in Las Vegas, NV, CorCell began as the first private cord blood company licensed for umbilical cord blood collection. We are committed to the highest ethical standards in serving our customers. As an industry leader, CorCell has collected umbilical cord blood stem cells from thousands of hospitals nationwide and around the world. We have a 100% track record of successful cord blood transplants. In fact, one of CorCell s stored specimens was used in the first known autologous transplant for childhood leukemia.* Credentials FDA registered for Human Cells, Tissue-based Products and Cellular Tissues (HCT/Ps) Registered with the FDA to serve as a cord blood bank Operating under cgmp standards Our daughter Holland was born three years ago and we banked her cord blood with CorCell without thinking twice. I have Lupus and my daughter could inherit the Lupus gene you never know what may happen. Heather Murray Texas Licensed in the states of NY, NJ, CA and MD Licensed as a Registered Laboratory in the State of Nevada and Licensed in Hematology, Bacteriology, and Immuniohematology Clinical Laboratory Improvement Amendments (CLIA) Certification participates in College of American Pathologists (CAP) Surveys Team member snapshots Vice President, Operations, Dr. Geoffrey O Neill, has more than 30 years experience in the stem cell industry, has processed more than 50,000 specimens and has published 78 papers. Dr. O Neill came to the United States in 1979 to work for the Memorial Sloan-Kettering Cancer Center in New York. He has also served as a professor at universities including Cornell and Columbia University. CorCell s Medical Director and Chairperson of the Medical and Scientific Advisory Board, Dr. Shamoon Ahmad, M.D., M.B.A., FACP, is currently Director of the Cancer Therapy & Integrative Medicine Institute in Las Vegas, Nevada. He also serves as President of the Nevada Oncology Society and is an Associate Professor at the Touro University School of Medicine in Las Vegas. * SOURCE: The Official Journal of the American Academy of Pediatrics. (2007). First report of autologous cord blood transplantation in the treatment of a child with leukemia. Pediatrics, 2007 (119), CorCell.com (888)

10 CorCell Advantages

11 Our process is unparalleled Obstetricians find our Collect-A-Cord kits safe, reliable and easy to use. A specialized medical courier transports your baby s cord blood to our new Las Vegas laboratory, under time and temperature guidelines, where it is tested according to FDA cellular therapy protocols. The initial cord blood collection volume averages ml and after processing is complete, your stem cells are stored in a 25 ml multicompartment cryobag. Finally, your baby s cord blood is frozen (cryopreserved) and then stored in our experienced, licensed, secure, cutting-edge cord blood banking facility with around-the-clock monitoring. We re oriented toward the future of medicine for the future of your children CorCell offers peerless cellular engineering for more therapeutic options now and in the future All specimens are tested to ensure the stem cells meet the rigid standards for transplantation or other therapeutic use. They are The Cord Blood Processing System evaluated for bacterial We use a functionally closed cord blood contamination and infectious processing system. disease. Also, the number of Our system is both sterile and manual, stem cells are counted both which provides a flexibility not available before and after processing. with automated systems like AXP or Sepax. Cord blood processed by Automated systems assume every cord CorCell will not be limited for blood collection is exactly the same, when use in only the straightforward in fact each sample is unique to the donor. transplants commonly Regardless of the size of the sample, the performed today, it will also processing solution used can be modified qualify for the manufactured to optimize cell yield: our technicians have control at each stage of the process. cell therapies of tomorrow developed by current research Interconnected 2-bag design and sterile efforts. This is a unique fluid path limits cell manipulation while advantage CorCell provides minimizing environmental contamination and identification errors with individual to our customers. component traceability. Katie arrived four weeks early, so I never finalized things to get our collection kit from CorCell. Diabetes and cancer run in our families so we didn t want to miss out on the opportunity to collect our newborn s cord blood. CorCell went out of their way to have the kit delivered to the hospital. It gives us peace of mind to know that CorCell has it if we ever need it. Koleen Cavanaugh Maryland 510k and FDA approved and manufactured under FDA Current Good Manufacturing Practice (cgmp) regulations. CorCell.com (888)

12 Collecting Cord Blood

13 Collecting cord blood is 100% painless and safe for mother and baby. Plus, it s free of religious or ethical controversy because life is being preserved and not discarded. Whether the birth is natural or cesarean makes no difference. The entire process is handled by your delivering physician or attending nurse. The procedure will not interfere with the birth process or post-partum bonding in any way. Collection: A painless, non-invasive and risk-free procedure Your Doctor s job CorCell s collection procedure is preferred by obstetricians for its safety, reliability and simplicity. The doctor or nurse will draw blood from the mother for hospital use as well as for infectious disease testing by the cord blood lab. It is important to make sure maternal blood is drawn utilizing the empty vials included in your kit. After the umbilical cord is cut, your doctor or attending nurse will follow CorCell s very simple cord blood collection procedure and collect the cord blood into a sterile closed-system bag that has the least chance of contamination. They will return the collected specimens to you in the Collect-A-Cord kit for courier pick up. Collect-A-Cord kit Our Collect-A-Cord kit features the PALL Medical Cord Blood Sterile Collection Bag, the only FDA approved collection bag. This innovative sterile bag makes it safe for all deliveries including c-sections. No need for additional sterile adapters. The bag is designed to maximize the recovery of cell-rich plasma and accommodates cord blood volumes of up to 210 ml. This collection bag also features an In-line DonorCare Needleguard, ensuring safer cord blood collection by providing an added level of safety for collection staff against accidental needlestick injuries. The Pall bag is FDA NDA approved and invidually inspected prior to release per cgmp standards. And each bag is trackable with unique lot numbers, further ensuring dependable quality control measures. True affordability. No hidden costs. Our enrollment fee includes testing, processing and even the expense of a private, insured medical courier. Because this service is so important we offer flexible payment options. You can select the best payment plan to meet your budget. Please ask us about our discount programs. You may qualify for one or more discounts! Additional features of our Collect-A-Cord kit include: Unique identification bar codes for each delivery Heparin free Individual instruction packets for both the parents and the delivery team Clear and concise instructions for packing the cord blood sample and shipping it back to the CorCell lab 24/7/365 CorCell phone support for both parents and delivery team Denser foam for increased transport protection Less packaging, which reduces our carbon footprint CorCell.com (888)

14 $50,000 Quality Service Guarantee If your child s cryopreserved cord blood is used for a stem cell transplant and fails to engraft, CorCell will pay the Client $50,000 to defray the cost of procurement of an alternative stem cell source, if medically indicated. Please see inside pocket for more details on this program. If you refer a friend who stores cord blood with CorCell, we ll send you a $200 cash card, and your friend will receive a $200 discount on the enrollment fee.* As a physician and researcher of stem cells and human cancers, I am encouraged with the advances in stem cell therapy, so much so, that I saved my own child s cord blood. And I was particularly impressed with how easy CorCell made the collection. Their procedure and blood storage facility is, in my opinion, the best in the profession. Carlo M. Croce, MD Director of the Kimmel Cancer Institute and Kimmel Cancer Center, Thomas Jefferson University You will feel good knowing you are providing your friends with valuable information that could help protect their child s future health. You don t have to be a CorCell customer to take advantage of Referral Rewards. *Program is subject to change at any time. For more information visit com/customers/referral-rewards, or see the card located in the inside pocket of this booklet. CorCell s Afford-A-Cord financing program makes saving your baby s cord blood easier than ever. One low enrollment fee and low monthly payments. It couldn t be easier. Pay only a $495 Enrollment and Cord Blood Processing Fee and $150 Medical Courier Fee when signing up, then pay only $19 per month over the life of the contract. For more information visit or see the application located in the inside pocket of this booklet. Always-here customer service We are here for any question you or your delivery team have 24/7/365. Our customer care representatives are available to help guide you through the easy enrollment process. We guarantee your satisfaction. Final thought: If you decide not to store your baby s cord blood with CorCell, please consider donating this precious gift of life to a public bank. Donations can be made at no cost to you.

15 Collecting cord blood is easy 1) Complete and Return the Enclosed Enrollment Forms Simply complete and sign the forms enclosed in the side pocket today. Return the completed contract and payment forms in one of three ways: 1) Fax to: (888) ) Scan and to: 3) Mail to: CorCell Companies, Inc Helm Drive Las Vegas, NV That s it! Once we receive your enrollment forms we will ship your Collect-A-Cord kit. Please call us at (888) if you have any questions or need assistance with filling out your enrollment forms. 2) Tell Your Doctor About Your Decision Your doctor should know in advance that you ll be collecting your baby s cord blood. CorCell will provide your doctor and hospital with instructions. If your doctor has any questions about CorCell or the procedure itself, he or she can call us directly on our toll-free number. We re available 24/7/365. 3) Have Your CorCell Collect-A-Cord Kit On Hand Once you ve enrolled with CorCell, we will send you an umbilical cord blood Collect-A-Cord kit to bring to the hospital with you when you are ready to deliver. The kit contains everything necessary, including the telephone number of the medical courier who will come to your hospital room to pick up the blood for transport directly to our laboratory. It is very important to keep the CorCell Collect-A-Cord kit at room temperature. Please do not store it in your car. 4) Bring Your Collect-A-Cord Kit to the Hospital When You Deliver Make sure to bring your CorCell Collect-A-Cord kit with you when you go to the hospital to deliver your baby. It s a good idea to keep it right alongside any overnight bag you may have already packed. Once the blood is collected, call our special 24-hour toll-free number (included in your Collect-A-Cord kit) and we will dispatch a medical courier right away. And that s it! With colon, ovarian, prostate and breast cancers on both the maternal and paternal sides of the family, we wanted to be proactive in the event we would have to tap into the umbilical cord blood for stem cells. We are thankful to be a CorCell customer. Anthony D Eramo Indiana Delivery Day Checklist Because we know things can happen very fast, here s a quick and easy checklist to help you make sure you remember everything you need to save your baby s cord blood. Put the Collect-A-Cord TM kit in or alongside your (expectant mother s) overnight bag. Do not store the kit in the trunk of your car. The kit must be stored at room temperature. When you arrive at the hospital remind your labor and delivery team that you are going to save your baby s umbilical cord blood. Give them the Collect-A-Cord kit. Inform the delivery staff that you (the expectant mother) need to have your blood drawn into the vials that are in the Collect-A-Cord kit. Ask your doctor to collect the cord blood as soon after the baby s birth as possible so that you maximize the volume of blood collected. The doctor or hospital staff will return the kit to you in your hospital room. Within one hour of your baby s birth call our medical courier at (800) The medical courier will pick up the kit within a few hours of receiving the call. Make sure the Collect-A-Cord kit stays at room temperature. Never refrigerate or freeze it. Keep the completed Collect-A-Cord kit with you at your bedside. Give the kit directly to the medical courier. Form No. MKT-001-CF.023 Approved 4/1/2012 Effective 4/1/2012 Version B CorCell.com (888)

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