It s not something you want to think about, but it s something you want to prepare for.

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1 It s not something you want to think about, but it s something you want to prepare for. StemCyte cord blood banking offers your family a new lifesaving treatment alternative

2 Why Bank Take the once-in-alifetime opportunity to protect your child s long-term health Cord blood provides a rich source of stem cells. To date, more than 80 diseases have been successfully treated with stem cells. You have only one opportunity to save your child s cord blood. Choosing the right cord blood bank can make the difference. Cord blood stem cells hold the power to cure Cord blood provides a rich source of stem cells for use in many situations where bone marrow is used today. StemCyte is the leader in cord blood banking. StemCyte has extensive experience providing cord blood units for transplants in children and adults with life-threatening diseases. What makes stem cells so different? Stem cells are different from other cells in the body in three main ways: Stem cells are unspecialized They have not developed into cells that perform a specific function. Stem cells can differentiate They can divide and produce cells that have the potential to become other more specific cell types, tissues, or organs. These new cells and tissues are used to repair or replace damaged or diseased cells in the body. Stem cells are capable of self-renewal Stem cells are able to divide and produce copies of themselves, which leads to self-renewal. Once a cell has become specialized (has differentiated) to a particular tissue or organ, it has a very limited capacity to self-renew (produce new stem cells), but instead it produces only cells relevant to that organ.

3 Why StemCyte Exceptional cell processing Our MaxCell processing method is a patented and proprietary process, offered only by StemCyte. The process removes only the plasma and recovers a higher number of stem cells, compared to other methods. MaxCell processing saves more of your baby s cord blood stem cells. $50,000 LifeSaver Guarantee backed by our public bank inventory Through our unique LifeSaver Guarantee, you can be confident that your cord blood is backed by one of the world s largest and most diverse inventories of cord blood units donated for public use. Units Provided for Transplants FACT AABB BBB Extensive transplant experience StemCyte has extensive experience providing cord blood units for transplants in children and adults with life-threatening diseases, but only StemCyte cord blood units have been used in almost 2,000 transplants to date, across 300 transplant centers. StemCyte CBR ViaCord 2, Yes No No s agencies and registries have recognized StemCyte for its dedication to higher standards and patient care. StemCyte is one of the few private cord blood banks that is both FACT and AABB accredited. FACT (Foundation for the of Cellular Therapy): The StemCyte US facility has maintained accreditation by FACT since AABB (formerly known as the American Association of Blood Banks): StemCyte has maintained accreditation by AABB since BBB (Better Business Bureau): StemCyte has been an accredited business since FDA Registered

4 What makes cord tissue lining stem cells special? Diseases currently treated with cord blood stem cells Cord tissue lining contains high numbers of epithelial and mesenchymal stem cells. Cord tissue lining is easily expanded, meaning that it is relatively easy to grow in culture to increase the total number of cells. Use of tissue cells Epithelial stem cells can differentiate into cells that make up the organs, including the skin, eyes, inner ear, liver, and pancreas. Mesenchymal stem cells can differentiate into bone cartilage, muscle, heart, fat, and nerve cells. Immune deficiency diseases Leukemia Lymphoma Diseases potentially treated with cord blood stem cells in the future (clinical trials in progress) Alzheimer s disease Autism Cerebral palsy Diabetes Heart disease Muscular dystrophy Multiple myeloma Sickle cell anemia Thalassemia Parkinson s disease Peripheral vascular disease Spinal cord injury Stroke Potential regenerative medicine applications of cord blood stem cells in the future (lab research in progress) Blood vessel repair Bone repair Brain repair Cardiac repair Cornea repair Hearing loss treatment Liver repair Skin repair

5 Bank with confidence. If your child s cord blood stem cells fail to engraft, StemCyte will refund all service fees, an additional $50,000, and provide a replacement sample from our donor bank. To enroll, call to speak with a cord blood banking advisor or visit our website at Call your local StemCyte representative for the latest specials. References 1. National Cancer Institute. (2014). Leukemia. Retrieved from gov/cancertopics/types/leukemia 2. National Cancer Institute. (2013, December 2). A snapshot of lymphoma. Retrieved from snapshot/lymphoma 3. Genetic Home Reference. (2012, August). Sickle cell disease. Retrieved from 4. National Cancer Institute. (2013). What you need to know about multiple myeloma. Retrieved from 5. National Institute of Allergy and Infectious Diseases. (2014, February). Primary Immune Deficiency Diseases. Retrieved from Pages/Default.aspx. 6. Genetic Home Reference. (2014, April). Alpha Thalassemia. Retrieved from aspx. 7. National Diabetes Education Program. The Facts About Diabetes: A Leading Cause of Death in the U.S. Retrieved from 8. National Institute of Health. (2014, March). Home Safety for People with Alzheimer s Disease. Retrieved from 9. National Institute of Neurological Disorders and Stroke. (2014, May). Parkinson s Disease: Hope Through Research. Retrieved from htm. 10. National Institute of Neurological Disorders and Stroke. (2014, May). Cerebral Palsy: Hope Through Research. Retrieved from palsy/detail_cerebral_palsy.htm. 11. National Institute of Neurological Disorders and Stroke. (2014, April). Spinal Cord Injury: Hope Through Research. Retrieved from nih.gov/disorders/sci/detail_sci.htm. 12. National Institute of Neurological Disorders and Stroke. (2014, April). Stroke: Hope Through Research. Retrieved from nih.gov/disorders/stroke/detail_stroke.html. 13. National Institute of Neurological Disorders and Stroke. (2014, April). Muscular Dystrophy: Hope Through Research. Retrieved from StemCyte. All rights reserved.

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