Saving lives globally through mutual miracles. LifeCord is a public non-profit cord blood bank licensed by the FDA.

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1 Saving lives globally through mutual miracles LifeCord is a public non-profit cord blood bank licensed by the FDA.

2 Donating your baby s cord to a public cord blood bank can save lives globally. You can play an important role in saving lives by donating the blood contained in your baby s umbilical cord to LifeCord, a non-profit cord blood bank. Donating blood is free and will not affect you, the baby or the birthing process. Hospital partners LifeCord currently collects umbilical cord blood at eight hospitals in Florida, Georgia and Alabama. Baptist Medical Center East Montgomery, Alabama Baptist Medical Center South Montgomery, Alabama East Alabama Medical Center Opelika, Alabama Jackson Hospital Montgomery, Alabama North Florida Regional Medical Center Gainesville, Florida UF Health Shands Hospital Gainesville, Florida Northeast Georgia Medical Center Gainesville, Georgia Piedmont Henry Hospital Stockbridge, Georgia We can t do it without you.

3 About cord blood donation What is cord blood? Cord blood is the blood remaining in the umbilical cord and placenta after a baby is born. Cord blood is rich with blood-forming cells. How is cord blood used? Each year, thousands of people are diagnosed with cancer and other life-threatening diseases, such as leukemia or sickle cell disease, that can be cured with a cord blood transplant. Cord blood transplants replace diseased blood-forming cells with healthy cells. The treatment process is similar to a bone marrow transplant, except that cord blood is used instead of marrow. Like marrow, cord blood is rich in stem cells which generate red blood cells to resist disease. A cord blood unit does not have to match a patient s tissue type as closely as donated marrow does. This means more patients are able to receive transplants. Who needs a cord blood transplant? Patients in need of a transplant quickly. Cord blood units are stored and ready to use immediately. Patients who have a hard time finding a matched bone marrow donor. Cord blood does not have to match a patient s tissue type as closely as donated bone marrow does. Patients from racially or ethnically diverse communities who often have uncommon tissue types. Because cord blood does not have to match the patient as closely as bone marrow does, it may offer more people from diverse racial and ethnic communities a second chance at life. What happens to cord blood if it is not donated? The umbilical cord, placenta and lifesaving blood they contain are usually discarded after birth. Is there any cost for donation? There is no cost for donating cord blood to a public cord blood bank, such as LifeCord. LifeCord incurs the cost of collecting, testing, processing and storing the cord blood. How is cord blood donated? Donating cord blood zo a public cord blood bank involves talking with your doctor or midwife about your decision to donate, and then contacting LifeCord if donation is an option at your hospital. Upon arriving at the hospital, remind the labor and delivery team that you are donating your umbilical cord blood. After the delivery of your baby, the umbilical cord and placenta are no longer needed. The blood remaining in the umbilical cord and placenta will be collected and tested. The collection procedure is painless and does not interfere with the normal birthing process. By donating umbilical cord blood, you choose to help someone in need of a potentially lifesaving transplant. Ethnic Diversity Not all patients are able to find a match on the NMDP registry. Patients from racially or ethnically diverse backgrounds often have uncommon tissue types. A patient s likelihood of finding a match on the Be The Match Registry is estimated to range from 66% to 93%, depending on race or ethnicity. African American or black patients have an estimated 66% likelihood of finding a match on the registry. What this means is that African-Americans are least likely to find a match. By increasing the number of minority cord blood units on the registry, minority patients will be more likely to find a match.

4 Common Misconceptions about Private Banking One of the most common misconceptions about private cord blood banking is that a child s own cord blood can be transplanted if he develops a disease later in life. In many cases, diseases such as leukemia, are genetic, so the cord blood that is banked at birth already carries the same disease. Most people who need transplants use cord blood donated by a sibling or a public cord blood bank. Cord blood recipients have about a 25 percent chance of matching a sibling and a 75 percent chance of finding a match from a public bank. Only a small percentage of babies (estimated at between 1 in 1,000 to 1 in 200,000) ever use their own, privately banked cord blood. The American Academy of Pediatrics 2007 Policy Statement on Cord Blood Banking states that: Physicians should be aware of the unsubstantiated claims of private cord blood banks made to future parents that promise to insure infants or family members against serious illnesses in the future by use of the stem cells contained in cord blood. The Cost of Private Cord Blood Banks Private cord blood banks charge mothers up front, including registration fees, harvesting and processing fees, and storage fees. LifeCord vs. Private Cord Blood Banks LifeCord Available for transplant to anyone globally FREE FREE LifeCord has provided cord blood units for 115 transplants in 27 states and 11 foreign countries. Together we can save lives all over the world. Private Cord Blood Bank May be available for you and your family I n i t i a l s t o r a ge f e e : a p p rox i m a t e l y $2000 Approximately $150 in yearly storage fees If the cord blood unit is requested for transplant for someone other than the donor, you incur the cost of transportation, HLA typing, disease and CD34 testing. LifeCord has provided cord blood units for 115 transplants in 27 states and 11 foreign countries. UK: 4 Washington: 2 Canada: 8 Massachusetts: 2 Oregon: 1 Minnesota: 14 Wisconsin: 1 New York: 4 Utah: 3 Illinois: 4 Michigan: 1 New Jersey: 1 5 California: 5 Virginia: 1 Kentucky: 3 Colorado: 3 S. Carolina: 1 N. Carolina: 1 Oklahoma: 3 Indiana: 1 Ohio: Pennsylvania: 2 Texas: 11 Tennessee: 1 Georgia: 1 Kansas: 2 Alabama: 1 Louisiana: 1 Florida: 3 Germany: 3 Netherlands: 2 France: 10 Switzerland: 2 Austria: 1 Israel: 2 Brazil: 3 Australia: 2

5 Devon Vickers received a cord blood transplant while undergoing treatment for leukemia. Today she s healthy thanks to a cord blood donor. When Braelyn Scott was born Jan. 30, 2013, she became her family s youngest blood donor. Just minutes after she was born, her doctor was able to collect the blood from her umbilical cord. I would love to have the opportunity to thank the mother and child who donated cord blood. To hear Devon s amazing story, visit youtube.com/lifesouthcbc It was very simple. I didn t have to do a thing, it was painless for me and the baby, and it was free, said Tiffany Scott, Braelyn s mom. Ask your doctor. Find out if it s an option at your hospital. Your tiny baby could be someone s lifesaver. Josh Ibarrientos received a cord blood transplant after battling leukemia for six years and is now cancer-free. Cord blood saves lives. Every time I know someone who is pregnant, I tell them your OB/GYN will give you some information on cord blood. Joshua is a living example that it really helps, don t let them waste it, if you can donate it, said Gea Ibarrientos ( Josh s mother). My friends, my relatives know how Josh was saved.

6 Diseases Treatable by Stem Cell Transplantation The following diseases may be treated by transplant using hematopoietic stem cells obtained from umbilical cord blood, peripheral blood or bone marrow under appropriately approved research protocols. Acute Lymphoblastic Leukemia (ALL) Acute Myelogenous Leukemia (AML) Chronic Myelogenous Leukemia (CML) Histiocytic Disorders Familial Erythrophagocytic Histiocyosis Histiocytosis-X Hemophagocytosis Other Histiocytic Disorders Hodgkin s Lymphoma Inherited Erythrocyte Abnormality Beta Thalassemia Major Fanconi Anemia Pure Red Cell Aplasia Sickle Cell Disease Inherited Immune System Disorders Ataxia-Telangiectasia Combined Immunodeficiency Kostmann Syndrome Leukocyte Adhesion Deficiency Chediak-Higashi Syndrome Ommenn s Syndrome Severe Combined Immunodeficiency (SCID) SCID with Adenosine Deaminase deficiency Absence of T & B Cells SCID Absence of T Cells, Normal B Cell SCID Other SCID Wiskott-Aldrich Syndrome X-Linked Lymphoproliferative Disorder Other Immune System Disorders Inherited Metabolism Disorders Adrenoleukodystrophy Sly Syndrome, Beta-Glucuronidase Deficiency Gaucher s Disease Hunter s Syndrome Hurler s Syndrome Krabbe Disease Maroteaux-Lamy Syndrome Metachromatic Leukodystrophy Neiman-Pick Disease Other Mucopolysaccharidosis Osteopetrosis Sanfilippo Syndrome Wolman Disease Other Inherited Metabolic Disorders Inherited Platelet Abnormalities Amegakaryocytosis/Congenital Thrombocytopenia Myelodysplastic Disorder Syndromes Acute Myelofibrosis Chronic Myelomonocytic Leukemia (CMML) Essential Thrombocythemia Idiopathic Sideroblastic Anemia Myelodysplastic Disorder Myelofibrosis /Myeloid Metaplasia Paroxysmal Nocturnal Hemoglobinuria Polycythemia Vera Refractory Anemia Refractory Anemia with Excess Blast Refractory Anemia with Excess Blast with Transformation Unknown Myelodysplastic Disorder Other Myelodysplastic Disorder Non-Hodgkin s Lymphoma Other Leukemia Acute Biphenotypic Leukemia Acute Undifferentiated Leukemia Chronic Lymphocytic Leukemia Juvenile Chronic Myelogenous Leukemia Prolymphocytic Leukemia Other Leukemia Other Malignancy Breast Cancer Renal Cell Carcinoma Other Non- Malignant Diseases Plasma Cell Disorders Multiple Myeloma Plasma Cell Leukemia Unknown Plasma Cell Disorders Waldenstrom s Macroglobulinemia Other Plasma Cell Disorder Severe Aplastic Anemia

7 About LifeSouth Who we are Founded in 1974, LifeSouth is a 501(c)(3) non-profit community blood supplier for hospitals in Alabama, Florida and Georgia. LifeSouth employs nearly 800 people throughout our footprint. With more than 1,000 blood drives a month, 32 donor centers and 42 bloodmobiles, LifeSouth supplies over 350,000 blood components to more than 100 community hospitals annually. Our mission To provide a safe blood supply that meets or exceeds the needs in each community we serve, and to provide a variety of services in support of ongoing and emerging blood and transfusion-related activities. LifeSouth received FDA licensure for cord blood manufacturing in June 2013, becoming the fifth cord blood bank nationwide that is licensed by the FDA. LifeCord LifeCord is a program of LifeSouth Community Blood Centers. Established in 1998, it was the first public cord blood bank in the Southeast. LifeCord collects umbilical cord blood from newborns at hospitals in Florida, Georgia and Alabama. As of August 2013, the stem cells from those collections have been used for 115 transplants in 27 states and 11 foreign countries (see map). The LifeCord staff has demonstrated a passion for this, and they are tirelessly working to provide a needed service. Receiving the FDA license indicates that we are meeting the highest and most stringent standards for providing high quality products to the patients we serve. This is an example of how the cooperative effort of how our partner hospitals and LifeSouth can work together to promote health. - LifeCord Medical Director Dr. John Wingard

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