Not All Stem Cells are the Same

Size: px
Start display at page:

Download "Not All Stem Cells are the Same"

Transcription

1 Cord Blood Banking and Transplantation Jennifer Willert, M.D. Hematology/Oncology Blood and Marrow Transplant Rady Children s Hospital San Diego Clinical Professor UCSD Not All Stem Cells are the Same Embryonic Stem Cells Newborn Stem Cells Cord Blood Advantages High developmental potential High proliferative capacity Little risk of viral contamination Younger, excellent proliferation and differentiation abilities Immediately available Less stringent HLA requirements Lower risk of GvHD, infections Autologous transplants possible Limitations Limited supply Ethical issues No clinical data Biological constraints Delayed short-term engraftment One-time supply Adult Stem Cells Bone Marrow Peripheral Blood Ability to differentiate Rich concentration of stem cells Greatest amount of historical data Rapid engraftment Good historical data Less invasive than bone marrow Facilitates easier autologous transplants Complex harvest Minimal residual disease (MRD) Increased potential for GvHD Cord Blood Stem Cell Timeline Cord blood proposed as source of stem cells First family cord blood stem cell bank (for use by related individual) NEJM study demonstrated higher survival rates with related cord blood cell transplants than with unrelated More than 10,000 transplants have been performed to date First cord blood stem cell transplant from a related donor for Fanconi's anemia First successful transplantation from an unrelated donor Stem Cell Therapeutic and Research Act signed into law Adapted from: Emerging stem cell therapies. Supplement to OBG Management

2 Cord Blood Stem Cells Are Increasingly Being Used to Save Lives Cord Blood Stem Cell (CBSC) Transplants Cord Blood Banking Options: Private and Public Private Cord Blood Banking: Related Banks 98% of collected samples are banked Samples are reserved and available at any time for family use Cost is ~$1500 to $2000 upon collection plus $100 to $125 annual storage fee Is an option accessible to anyone in the United States Public Cord Blood Banking: Unrelated Donor Banks 48% 66% of all samples collected are banked Sample is available to any matched recipient; not all patients will find a match No cost for collection or storage; cost is ~$15,000 to $35,000 to the treating institution for sample retrieval Access denied to some due to limited number of public banks Both options help address the potential needs of patients Diseases That Could Currently Benefit From CBSC Transplants Blood Disorders Sickle Cell Anemia Aplastic Anemia Fanconi Anemia Beta Thalassemia Malignancies Leukemia Lymphoma Multiple Myeloma Metabolic Disorders Hurler Syndrome Niemann Pick Disease Severe Combined Immune Deficiency Many Emerging Therapies are Under Investigation Including Heart Disease, Diabetes, and Brain Injury 2

3 Blood and Marrow Transplant Approximately 500 CBSC transplants occur annually in the U.S. Many Patients Don t Find a Match Patients Needing Bone Marrow Transplants 33% Family Match 66% No Family Match Bone Marrow Transplant Registry 25% Find Suitable Match Up to 50% of All Patients Needing Stem Cell Transplants Are Unable to Find a Match Up to 75% Find No Suitable Match Source: 1) Perlow JH. Contemp Ob/Gyn Advantages of CBSC Over Bone Marrow Immediate availability Simpler collection process Elimination of surgical harvest Reduction in time to treatment Decrease in frequency of certain infections More tolerant of HLA mismatches Lower risk of GvHD Provide better long term immune function Source: 1) Emerging stem cell therapies. OBG Management. 2006;18(suppl):S1-S6. 3

4 Outcomes of CBSC Transplants Compared With Bone Marrow in Children Outcome Acute GvHD Chronic GvHD Time to Engraftment Early Transplant Related Mortality Relapse Survival Cord Blood Improved Improved Slightly Longer Equivalent Equivalent Equivalent Cord Blood Stem Cell Transplantation Provides Improved Outcomes for Patients Advantages of Related CBSC Genetically unique to child or sibling Increased chance of intra familial matching Known family history Decreased morbidity/mortality Readily available/accessible Source: 1) Gluckman E, et al. NEJM CBSC Transplants Are Highly Successful, Particularly in Related Stem Cell Transplants One Year Survival % 29% N=78 Provide best clinical outcomes Less GvHD Improved survival Related CBSC Transplants Unrelated CBSC Transplants Higher Clinical Success Rates With Related CBSC Transplants² 85% 72% 3% Engraftment Survival GvHD N=44 Genetically unique Known family history Immediately available/accessible Expected lower costs No sample procurement Less acute GvHD treatment Fewer chronic GvHD medication requirements Sources: 1. Gluckman E et al. N Engl J Med Wagner J et al. Lancet

5 Brandyn 14 year old male Diagnosed with leukemia as a toddler Years of chemotherapy led to remission, until relapse and need for stem cell transplant Blood from younger siblings umbilical cord and placenta was banked at birth Stored at a private bank, alleviating the need to find a match from donor hospital or public registry Blood was rich in stem cells November 2, 1999 Brandon received his cord blood transplant and continues to do well. It was enough to do the transplant. It was the most wonderful news I ve ever heard. Brandyn s Mother Titus Diagnosed at 18 months with aplastic anemia He was unable to produce any red blood cells on his own Titus s mother became pregnant again; the hospital recommended that the family store the cord blood stem cells with Cord Blood Registry The baby s cord blood was collected at no cost, as part of CBR s Designated Transplant Program Stem cells were found to be a perfect match December 30, 2004,Titus received his cord blood transplant and is doing well As a mother, you ll do anything to help you son. I m really glad the hospital recommended Cord Blood Registry. Titus s Mother Joseph Jr. 6 year old male Diagnosed at birth with sickle cell anemia Joseph required frequent blood transfusions Joseph s mother became pregnant with a second child Amniocentesis revealed that the baby was a perfect match for Joseph Jr. Joseph s younger brother s umbilical cord blood was banked at birth free of charge as part of CBR s Designated Transplant Program The transplanted stem cells created new blood and a new immune system More than five years after the transplant, Joseph is healthy and vibrant It was about 20 days after the transplant when all of a sudden he started feeling better. Joseph s Father 5

6 Designated Transplant Program Established in 1996 to increase accessibility of stem cell transplantation to patients in need Eligibility criteria Affected family member is first or second degree relative of newborn Treating transplant physician confirms that affected family member is in need of a stem cell transplant All expenses of collection, processing, and storage are waived for DTP clients Through the DTP, CBR has stored cells for over 2000 families Empower Patients to Make an Informed Choice for the Future Who should receive information about cord blood banking? All expectant parents Family history of genetic disorders may pose particular need for education about cord blood banking Preparing for a Healthy Birth and Life CBSC banking discussed if multiple ethnicity exists (Initial visit) Maternal Serum Screen Ultrasound (15 20 weeks) Oral Glucose Challenge Test (28 weeks) BPP Non Stress Test (Post week 30) Weeks Initial hgc pregnancy test Prenatal Blood screening Rh incompatibility test & urinalysis CVS Nuchal Translucency Sono (Initial visit-14 weeks) Introduce CBSC banking options (20 weeks) Amniocentesis (Post week 16) PUBS (18 36 weeks) Cord Blood Collection (At delivery) Throughout Pregnancy Numerous Tests Are Conducted to Ensure the Present and Future Health of Mother and Baby 6

7 National and State Public Policy Continue to Drive Stem Cell Education and Awareness In addition to an Institute of Medicine (IOM) report and federal legislation centered on the creation of a national public bank, Cord Blood legislation has passed in 20 states. Odds of Use Odds Of Usage Over 70-year Span Based Solely On Current Indications 1 *: Autologous 1 in 400 chance of being a SC transplant recipient Autologous/Allogeneic 1 in 200 chance of being a SC transplant candidate Does Not Include Emerging, Potential Uses of Cord Blood Stem Cells to Treat Heart Disease, Diabetes, Parkinson s, Stroke, Muscular Dystrophy, and Spinal Cord Injury Source: 1) Pasquini MC, et al. Blood Factors Patients Need to Consider When Assessing a Cord Blood Bank Experience How many medical centers have utilized cells in transplant that were processed and stored with the cord blood bank? How recently? How many clients have samples stored at their facility? What is the longest time a unit has been stored and then used in a transplant? Cell recovery What percentage of cells do they recover from their processing? Publication of results Have they published data to support their processing and storage methods? Financial stability How long has the company been in operation and are they likely to be around in the future? Location of facility Are there risks associated with the location of the storage facility (tornadoes, hurricanes, airport closures, etc)? 7

8 Cord Blood Stem Cells Clinical studies over the past 20 years demonstrate the efficacy and safety of cord blood stem cells Cord blood stem cells can be easily collected and stored Cord blood stem cells are clinically useful in a variety of disease states and demonstrate tremendous future potential All expectant families should receive information about their options for collecting and storing their child s cord blood stem cells OBs play a vital role in ensuring families receive accurate information 8

Your Cord Blood Donation Options

Your Cord Blood Donation Options Your Cord Blood Donation Options Our Mission To develop and maintain a statewide resource for potentially life-saving cord blood to treat children and adults. What is cord blood? Cord blood is the blood

More information

It s not something you want to think about, but it s something you want to prepare for.

It s not something you want to think about, but it s something you want to prepare for. It s not something you want to think about, but it s something you want to prepare for. StemCyte cord blood banking offers your family a new lifesaving treatment alternative Why Bank Take the once-in-alifetime

More information

SAVE A LIFE... BY GIVING LIFE!

SAVE A LIFE... BY GIVING LIFE! SAVE A LIFE... BY GIVING LIFE! FOLLOW US ON: HÉMA-QUÉBEC PUBLIC CORD BLOOD BANK www.hema-quebec.qc.ca Scan this code with your smart phone to access the page Register to the Public Cord Blood Bank on the

More information

What we will discuss today

What we will discuss today Umbilical cord blood banking It s Utility? Dr. Nita Radhakrishnan Pediatric Hematology Oncology Unit, Sir Ganga Ram Hospital, New Delhi What we will discuss today What are stem cells? What are the sources

More information

Your Cord Blood Donation Options

Your Cord Blood Donation Options Your Cord Blood Donation Options What is cord blood? Cord blood is the blood that remains in the placenta after a baby is born. Cord blood has been found to be a rich source of stem cells and can be used

More information

Cord Cor Blood Banking Scott N. Furlan, MD Ellen S. Plummer, Plummer MD

Cord Cor Blood Banking Scott N. Furlan, MD Ellen S. Plummer, Plummer MD Cord Blood Banking Scott N. Furlan, MD Ellen S.Plummer, MD Overview Background Biology of Stem Cell Transplant Opportunities i at Parkland Logistics of Banking Potential Barriers Indications for HCT Cancer

More information

Canadian Blood Services National Public Cord Blood Bank Give Life Twice Transfusion Medicine Residents

Canadian Blood Services National Public Cord Blood Bank Give Life Twice Transfusion Medicine Residents Canadian Blood Services National Public Cord Blood Bank Give Life Twice Transfusion Medicine Residents Eileen Quinlan Collection Supervisor, Brampton (GTA) 2015-11-10 History One Match Stem Cell and Marrow

More information

Cord Blood Stem Cell Transplantation

Cord Blood Stem Cell Transplantation LEUKEMIA LYMPHOMA MYELOMA FACTS Cord Blood Stem Cell Transplantation No. 2 in a series providing the latest information on blood cancers Highlights Umbilical cord blood, like bone marrow and peripheral

More information

4. All cord blood banks should be subject to the same standards, regulations and accreditation requirements.

4. All cord blood banks should be subject to the same standards, regulations and accreditation requirements. WMDA Policy Statement on the Utility of Autologous or Family Cord Blood Unit Storage The WMDA Board adopted this policy on 25 th of May 2006. Policy updated _April 2011 The Cord Blood Working Group and

More information

UMBILICAL CORD BLOOD BANKING A guide for parents

UMBILICAL CORD BLOOD BANKING A guide for parents UMBILICAL CORD BLOOD BANKING A guide for parents 2 nd EDITION INTRODUCTION The cells contained in the umbilical cord blood have therapeutic value for the treatment of blood disorders and immune diseases.

More information

UMBILICAL CORD BLOOD, STEM CELL BANKING

UMBILICAL CORD BLOOD, STEM CELL BANKING UMBILICAL CORD BLOOD, STEM CELL BANKING Dr.Sharad Jain MD Blood Transfusion officer, & I/C Transfusion Medicine NSCB Medical College. Jabalpur.MP. Introduction: Every parent during childbirth DREAMS the

More information

SAVE A LIFE... BY GIVING LIFE! Information guide and registration Héma-QUEBEC PUBLIC CORD BLOOD BANK

SAVE A LIFE... BY GIVING LIFE! Information guide and registration Héma-QUEBEC PUBLIC CORD BLOOD BANK SAVE A LIFE... BY GIVING LIFE! Information guide and registration Héma-QUEBEC PUBLIC CORD BLOOD BANK Table of contents Introduction... 2 History of the Public Cord Blood Bank... 3 Transplantation and

More information

Discover the Possibilities Born With Your Baby

Discover the Possibilities Born With Your Baby Discover the Possibilities Born With Your Baby Your Simple Guide to Saving Cord Blood The Power and Promise The lifesaving power of cord blood and regenerative healing potential of cord blood and cord

More information

H. R. 2107 IN THE HOUSE OF REPRESENTATIVES

H. R. 2107 IN THE HOUSE OF REPRESENTATIVES I 1TH CONGRESS 1ST SESSION H. R. 2107 To direct the Secretary of Health and Human Services to conduct a public education campaign on umbilical cord blood stem cells, and for other purposes. IN THE HOUSE

More information

STEM CELLS : A THERAPEUTIC REVOLUTION JACQUES KADOCH ROBERT HEMMINGS MARINELA MANDRA

STEM CELLS : A THERAPEUTIC REVOLUTION JACQUES KADOCH ROBERT HEMMINGS MARINELA MANDRA STEM CELLS : A THERAPEUTIC REVOLUTION JACQUES KADOCH ROBERT HEMMINGS MARINELA MANDRA OVO CLINIC I 8000 BLVD DECARIE, MONTREAL QC H4P 2S4 I 514.798.2000 I OVOCLINIC.COM 2 a therapeutic revolution As the

More information

Narrator: Transplants using stem cells from the blood, bone marrow or umbilical cord blood

Narrator: Transplants using stem cells from the blood, bone marrow or umbilical cord blood [Track 2: What Is a Transplant?] Narrator: Transplants using stem cells from the blood, bone marrow or umbilical cord blood can be an effective treatment for people with blood cancers such as leukemia,

More information

UMBILICAL CORD BLOOD TRANSPLANTATION: KFSH EXPERIENCE

UMBILICAL CORD BLOOD TRANSPLANTATION: KFSH EXPERIENCE UMBILICAL CORD BLOOD TRANSPLANTATION: KFSH EXPERIENCE HIND AL HUMAIDAN, MD,FRCPA Director, Blood Bank (Donor & Transfusion Services) and Stem Cell Cord Blood Bank Consultant Hematopathologist INTRODUCTION

More information

5. All cord blood banks should be subject to the same standards, regulations and accreditation requirements.

5. All cord blood banks should be subject to the same standards, regulations and accreditation requirements. WMDA Policy Statement for the Utility of Autologous or Family Cord Blood Unit Storage (This policy statement has been approved and adopted by the WMDA board on the 25 th of May 2006) The Cord Blood Registries

More information

Saving Your Baby s Cord Blood

Saving Your Baby s Cord Blood Saving Your Baby s Cord Blood An Important Pregnancy Decision 1-888-CORD BLOOD HEALTHY FUTURES ARE Born at CBR For every parent who wishes they could do more to protect their family s health, there s Cord

More information

The Facts about Cord Blood

The Facts about Cord Blood The Facts about Cord Blood Dear Future Mom and/or Dad, All of us at CorCell would like to give you a big CONGRATULATIONS on your new baby! Now that you are expecting, you have probably heard about saving

More information

CORD BLOOD BANKING FAQ

CORD BLOOD BANKING FAQ CORD BLOOD BANKING FAQ Cord Blood & Stem Cells Q: What is umbilical cord blood (UCB)? A: Bone marrow, peripheral blood and UCB constitute the three primary sources of stem cells. Cord blood, which, until

More information

Cord blood banking: information for parents

Cord blood banking: information for parents Cord blood banking: information for parents Published August 2006 by the RCOG Contents Page number Key points 1 About this information 2 What is cord blood? 2 Why is cord blood useful? 3 How is cord blood

More information

cord blood saves lives...

cord blood saves lives... cord blood saves lives... ...by providing a rich source of blood stem cells that can be used to treat over 80 different diseases including leukemia, lymphoma, thalassemia, Tay-Sachs and sickle cell anemia.

More information

PT CordLife Indonesia Premium Cordblood Bank. PT CordLife Indonesia Premium Cordblood Bank

PT CordLife Indonesia Premium Cordblood Bank. PT CordLife Indonesia Premium Cordblood Bank Cordblood Stem Cells and The Role of Cordblood Bank in Supporting Stem Cells Research Presentation Overview Company profile Haematopoietic stem cells in cordblood What we can do to help 1 2 PT CordLife

More information

DEPARTMENT OF BONE MARROW AND STEM CELL TRANSPLANT

DEPARTMENT OF BONE MARROW AND STEM CELL TRANSPLANT www.narayanahealth.org DEPARTMENT OF BONE MARROW AND STEM CELL TRANSPLANT About Narayana Health City Narayana Health, one of India's largest and the world's most economical healthcare service providers

More information

ASSEMBLY, No. 2591 STATE OF NEW JERSEY. 212th LEGISLATURE INTRODUCED FEBRUARY 23, 2006

ASSEMBLY, No. 2591 STATE OF NEW JERSEY. 212th LEGISLATURE INTRODUCED FEBRUARY 23, 2006 ASSEMBLY, No. STATE OF NEW JERSEY th LEGISLATURE INTRODUCED FEBRUARY, 00 Sponsored by: Assemblywoman CHARLOTTE VANDERVALK District (Bergen) SYNOPSIS Requires hospitals to provide information to pregnant

More information

A Guide To Cord Blood Banking

A Guide To Cord Blood Banking A Guide To Cord Blood Banking For Families with Genetic Conditions Cord Blood Banking This leaflet is aimed at families who might be considering storing cord blood for the treatment of a child or other

More information

AssureImmune. Cord Blood: For Something That Precious, Bank with the Best. Important Facts for When You re Expecting. AssureImmune.

AssureImmune. Cord Blood: For Something That Precious, Bank with the Best. Important Facts for When You re Expecting. AssureImmune. AssureImmune AssureImmune Cord Blood: For Something That Precious, Bank with the Best Important Facts for When You re Expecting Banking your baby s umbilical cord blood could be a potentially lifesaving

More information

House Resolution No. 37

House Resolution No. 37 california legislature regular session House Resolution No. Introduced by Assembly Member Hill August, House Resolution No. Relative to umbilical cord blood banking. WHEREAS, Since the first umbilical

More information

Statement of Joanne Kurtzberg, M.D.

Statement of Joanne Kurtzberg, M.D. Statement of Joanne Kurtzberg, M.D. President of the Cord Blood Association Jerome Harris Distinguished Professor of Pediatrics and Pathology Chief Scientific Officer and Medical Director, Robertson Clinical

More information

UMBILICAL CORD BLOOD BANKING. A guide for parents

UMBILICAL CORD BLOOD BANKING. A guide for parents UMBILICAL CORD BLOOD BANKING A guide for parents This guide has been elaborated by the Council of Europe European Committee on Organ Transplantation (CD-P-TO). For more information, please visit https://go.edqm.eu/transplantation.

More information

umbilical cord blood banking A guide for parents

umbilical cord blood banking A guide for parents umbilical cord blood banking A guide for parents 2 nd Edition 2016 This guide has been elaborated by the Council of Europe European Committee on Organ Transplantation (CD-P-TO). For more information, please

More information

Stem Cell Background Paper

Stem Cell Background Paper Stem Cell Background Paper Introduction...2 Stem Cell Basics...3 Stem Cell Process Flow...9 Comparison of Blood, Stem Cells, Tissues and Organs Processes...10 Responsibilities for the Blood, Stem Cells,

More information

Clinical Research Program Information for Patients. Transplant Creations

Clinical Research Program Information for Patients. Transplant Creations Clinical Research Program Information for Patients Transplant Creations 1 Program Focus Combination chemotherapy and transplantation of stem cells from an autologous donor (patient s own stem cells) and/or

More information

Bone Marrow Transplantation and Peripheral Blood Stem Cell Transplantation: Questions and Answers. Key Points

Bone Marrow Transplantation and Peripheral Blood Stem Cell Transplantation: Questions and Answers. Key Points CANCER FACTS N a t i o n a l C a n c e r I n s t i t u t e N a t i o n a l I n s t i t u t e s o f H e a l t h D e p a r t m e n t o f H e a l t h a n d H u m a n S e r v i c e s Bone Marrow Transplantation

More information

Phone: +44 20 8123 2220 Fax: +44 207 900 3970 office@marketpublishers.com http://marketpublishers.com

Phone: +44 20 8123 2220 Fax: +44 207 900 3970 office@marketpublishers.com http://marketpublishers.com Global Stem Cell Umbilical Cord Blood (UCB) Market (Storage Service, Therapeutics, Application, Geography) - Size, Share, Global Trends, Analysis, Opportunities, Growth, Intelligence and Forecast, 2012-2020

More information

guides BIOLOGY OF AGING STEM CELLS An introduction to aging science brought to you by the American Federation for Aging Research

guides BIOLOGY OF AGING STEM CELLS An introduction to aging science brought to you by the American Federation for Aging Research infoaging guides BIOLOGY OF AGING STEM CELLS An introduction to aging science brought to you by the American Federation for Aging Research WHAT ARE STEM CELLS? Stem cells are cells that, in cell cultures

More information

A Cure for Sickle Cell Anemia and Thalassemia

A Cure for Sickle Cell Anemia and Thalassemia IV Simpósio Internacional de Hemoglobinopatias A Cure for Sickle Cell Anemia and Thalassemia Bertram Lubin, MD and Mark Walters, MD 4 September 2007 Topics to be covered Cord blood: Importance and biology

More information

Blood-Forming Stem Cell Transplants

Blood-Forming Stem Cell Transplants Blood-Forming Stem Cell Transplants What are bone marrow and hematopoietic stem cells? Bone marrow is the soft, sponge-like material found inside bones. It contains immature cells known as hematopoietic

More information

A Gift for life. HTA Licence No. 22653

A Gift for life. HTA Licence No. 22653 A Gift for life HTA Licence No. 22653 2 3 the best possible gift for your new born child. 4 6 8 9 10 12 14 16 19 what is cord blood current treatments services contents properties for treatment process

More information

Pros and Cons of Stem Cell Sources and their availability in Africa. Dr Jaimendra Singh Inkosi Albert Luthuli Central Hospital Durban, South Africa

Pros and Cons of Stem Cell Sources and their availability in Africa. Dr Jaimendra Singh Inkosi Albert Luthuli Central Hospital Durban, South Africa Pros and Cons of Stem Cell Sources and their availability in Africa Dr Jaimendra Singh Inkosi Albert Luthuli Central Hospital Durban, South Africa Introduction The ability to perform a haematopoietic stem

More information

Jamie Peregrine, MD, PGY-4 KU-Wichita, OB/GYN Wesley Medical Center

Jamie Peregrine, MD, PGY-4 KU-Wichita, OB/GYN Wesley Medical Center Jamie Peregrine, MD, PGY-4 KU-Wichita, OB/GYN Wesley Medical Center Uses for umbilical cord stem cells Describe the indications and uses for umbilical cord stem cells. Counsel patients on the advantages

More information

Donate your baby s cord blood and save lives.

Donate your baby s cord blood and save lives. Donate your baby s cord blood and save lives. A public nonprofit cord blood bank licensed by the FDA Each year, thousands of people are diagnosed with life-threatening diseases that may be cured with a

More information

A fact sheet UNRELATED BONE MARROW AND CORD BLOOD STEM CELL TRANSPLANTS

A fact sheet UNRELATED BONE MARROW AND CORD BLOOD STEM CELL TRANSPLANTS A fact sheet UNRELATED BONE MARROW AND CORD BLOOD STEM CELL TRANSPLANTS Each year, thousands of patients are diagnosed with diseases treatable by a blood stem cell transplant. These blood stem cells can

More information

What is a Stem Cell Transplantation?

What is a Stem Cell Transplantation? What is a Stem Cell Transplantation? Guest Expert: Stuart, MD Associate Professor, Medical Oncology www.wnpr.org www.yalecancercenter.org Welcome to Yale Cancer Center Answers with Drs. Ed and Ken. I am

More information

STEM CELLS FROM THE UMBLICAL CORD BLOOD AND UMBLICAL CORD TISSUE

STEM CELLS FROM THE UMBLICAL CORD BLOOD AND UMBLICAL CORD TISSUE STEM CELLS FROM THE UMBLICAL CORD BLOOD AND UMBLICAL CORD TISSUE What are Stem Cells? Stem cells are the basic building blocks of all the cells, tissues and organs in the human body. The role of the stem

More information

UMBILICAL CORD BLOOD COLLECTION

UMBILICAL CORD BLOOD COLLECTION UMBILICAL CORD BLOOD COLLECTION by Frances Verter, PhD Founder & Director, Parent's Guide to Cord Blood Foundation info@parentsguidecordblood.org and Kim Petrella, RN Department of Obstetrics and Gynecology

More information

Helping you find the one match.. Guide for Unrelated Stem Cell Transplant Patients OneMatch Stem Cell and Marrow Network BLOOD.

Helping you find the one match.. Guide for Unrelated Stem Cell Transplant Patients OneMatch Stem Cell and Marrow Network BLOOD. Helping you find the one match.. Guide for Unrelated Stem Cell Transplant Patients OneMatch Stem Cell and Marrow Network BLOOD.CA WWW This guide is intended for patients in need of an unrelated volunteer

More information

Ethical issues in stem cell research and application

Ethical issues in stem cell research and application Ethical issues in stem cell research and application Dr. Jeff Blackmer MD MHSc FRCPC Vice President Medical Professionalism Canadian Medical Association Ottawa, ON May 2016 Outline Ethics and stem cells

More information

Stem Cell Transplantation and the Canadian First Nations Community. Becky Luk (PTLS) Tanya Petraszko, MD

Stem Cell Transplantation and the Canadian First Nations Community. Becky Luk (PTLS) Tanya Petraszko, MD Stem Cell Transplantation and the Canadian First Nations Community Becky Luk (PTLS) Tanya Petraszko, MD Why is there a need for stem cells? Our Story Why are we engaging the First Nations, Metis and Inuit

More information

CBAN: Cord Blood Education Guide. CBANetwork. Cord Blood Advocacy Network

CBAN: Cord Blood Education Guide. CBANetwork. Cord Blood Advocacy Network INTRODUCTION Members are provided, free-of-charge, brochures and business cards customized with their CBAN #, contact information, CBAN special discount and their regional manager s contact information.

More information

Bone Marrow (Stem Cell) Transplant for Sickle Cell Disease

Bone Marrow (Stem Cell) Transplant for Sickle Cell Disease Bone Marrow (Stem Cell) Transplant for Sickle Cell Disease Bone Marrow (Stem Cell) Transplant for Sickle Cell Disease 1 Produced by St. Jude Children s Research Hospital Departments of Hematology, Patient

More information

CHAPTER 1 BACKGROUND AND CORD BLOOD BANK (CBB) ORGANIZATION

CHAPTER 1 BACKGROUND AND CORD BLOOD BANK (CBB) ORGANIZATION CHAPTER 1 BACKGROUND AND CORD BLOOD BANK (CBB) ORGANIZATION Chapter 1 BACKGROUND AND CORD BLOOD BANK (CBB) ORGANIZATION 1.1 OVERVIEW OF THE CORD BLOOD TRANSPLANTATION STUDY Bone marrow transplantation

More information

In a number of genetic, hematologic, and oncologic

In a number of genetic, hematologic, and oncologic AMERICAN ACADEMY OF PEDIATRICS Cord Blood Banking for Potential Future Transplantation: Subject Review ABSTRACT. In recent years, umbilical cord blood, which contains a large number of hematopoietic stem

More information

your complete stem cell bank

your complete stem cell bank your complete stem cell bank HYDERABAD - 88985 000 888, WARANGAL - 8297 256 777 VISAKHAPATNAM - 7799 990 774 VIJAYAWADA AND GUNTUR - 7799 990 771 NELLORE - 7799 990 772, KADAPA - 8297 256 700 RAJAHMUNDRY

More information

EUROCORD. in 49 countries and 484 transplant centres* 264 EBMT 4847 (73%) cases 220 Non-EBMT 1797 (27%) cases

EUROCORD. in 49 countries and 484 transplant centres* 264 EBMT 4847 (73%) cases 220 Non-EBMT 1797 (27%) cases ! 21%! EUROCORD 6756 cord blood transplantations performed from 1988 to March 2010 in 49 countries and 484 transplant centres* 264 EBMT 4847 (73%) cases 220 Non-EBMT 1797 (27%) cases * missing center

More information

07 SB148/FA/1 A BILL TO BE ENTITLED AN ACT

07 SB148/FA/1 A BILL TO BE ENTITLED AN ACT 0 SB/FA/ Senate Bill By: Senators Shafer of the th, Staton of the th, Thomas of the th, Rogers of the st, Heath of the st and others A BILL TO BE ENTITLED AN ACT AS PASSED SENATE 0 To amend Title of the

More information

UMBILICAL CORD BANKING. (formerly Unistem Biosciences Pvt.Ltd.)

UMBILICAL CORD BANKING. (formerly Unistem Biosciences Pvt.Ltd.) UMBILICAL CORD BANKING (formerly Unistem Biosciences Pvt.Ltd.) INITIATIVES OF CELLUGEN BIOTECH PVT.LTD. (formerly Unistem Biosciences Pvt.Ltd.) UMBILICAL CORD BANKING UMBILICAL CORD STEM CELL THERAPY Stem

More information

BCSLS Telehealth Stem Cell Transplantation. Becky Luk, Patient & Transplant Liaison Specialist

BCSLS Telehealth Stem Cell Transplantation. Becky Luk, Patient & Transplant Liaison Specialist BCSLS Telehealth Stem Cell Transplantation Becky Luk, Patient & Transplant Liaison Specialist Our Story Why is there a need for stem cells? What is OneMatch Stem Cell & Marrow Newtork s role in Stem Cell

More information

BCSLS Telehealth Stem Cell Transplantation. Our Story. Diseases treated with stem cell transplants. Why is there a need for stem cells?

BCSLS Telehealth Stem Cell Transplantation. Our Story. Diseases treated with stem cell transplants. Why is there a need for stem cells? BCSLS Telehealth Stem Cell Transplantation Becky Luk, Patient & Transplant Liaison Specialist Our Story Why is there a need for stem cells? What is OneMatch Stem Cell & Marrow Newtork s role in Stem Cell

More information

SEARCHING FOR A BONE MARROW DONOR

SEARCHING FOR A BONE MARROW DONOR SEARCHING FOR A BONE MARROW DONOR Angela received a bone marrow transplant from an unrelated donor to treat her non-hodgkin s lymphoma. INFORMATION FOR PATIENTS AND THEIR FAMILIES For patients who need

More information

My Sister s s Keeper. Science Background Talk

My Sister s s Keeper. Science Background Talk My Sister s s Keeper Science Background Talk Outline Acute promyelocytic leukemia (APL) APL Treatment Savior Siblings In vitro fertilization (IVF) Pre-implantation Genetic Diagnosis (PGD) Risks of donating

More information

Outcome of Unrelated HSCT in Patients Lacking HLA Matched Related Donors: Iranian Stem Cell Donor Program (ISCDP)

Outcome of Unrelated HSCT in Patients Lacking HLA Matched Related Donors: Iranian Stem Cell Donor Program (ISCDP) Outcome of Unrelated HSCT in Patients Lacking HLA Matched Related Donors: Iranian Stem Cell Donor Program (ISCDP) October 18, 2014 19th Congress of APBMT, Hangzhou, China AMIR ALI HAMIDIEH, MD Iranian

More information

Public Cord Blood Tissue Bank Committee on Health Care Services and Representative Peaden

Public Cord Blood Tissue Bank Committee on Health Care Services and Representative Peaden HOUSE OF REPRESENTATIVES COMMITTEE ON HEALTH CARE SERVICES ANALYSIS BILL #: HB 2337 (PCB HCS 00-07) RELATING TO: SPONSOR(S): TIED BILL(S): Public Cord Blood Tissue Bank Committee on Health Care Services

More information

The Leading Cell Bank www.stemology.co.uk. Protect Your Family s Future. Stem Cell Banking. Umbilical Cord. Only for Expecting Parents

The Leading Cell Bank www.stemology.co.uk. Protect Your Family s Future. Stem Cell Banking. Umbilical Cord. Only for Expecting Parents Protect Your Family s Future The Leading Cell Bank www.stemology.co.uk Stem Cell Banking Umbilical Cord Only for Expecting Parents Introduction to Stemology Imagine you could replace any cells in your

More information

Stem Cell Banking. Umbilical Cord. The Leading Cell Bank www.stemology.co.uk. Protect your family s future

Stem Cell Banking. Umbilical Cord. The Leading Cell Bank www.stemology.co.uk. Protect your family s future Protect your family s future The Leading Cell Bank www.stemology.co.uk Stem Cell Banking Umbilical Cord For women in their 1st, 2nd or 3rd Trimester of Pregnancy Introduction to Stemology Imagine you

More information

Stem Cell Quick Guide: Stem Cell Basics

Stem Cell Quick Guide: Stem Cell Basics Stem Cell Quick Guide: Stem Cell Basics What is a Stem Cell? Stem cells are the starting point from which the rest of the body grows. The adult human body is made up of hundreds of millions of different

More information

Fetal Maternal Immunity and Antileukemia Activity in Cord Blood Transplant. Recipients

Fetal Maternal Immunity and Antileukemia Activity in Cord Blood Transplant. Recipients Fetal Maternal Immunity and Antileukemia Activity in Cord Blood Transplant Recipients Filippo Milano, 1 J. Lee Nelson, 1, 2 Colleen Delaney 1,3 1 Clinical Research Division, Fred Hutchinson Cancer Research

More information

Hematopoietic Stem Cell Transplantation. Imad A. Tabbara, M.D. Professor of Medicine

Hematopoietic Stem Cell Transplantation. Imad A. Tabbara, M.D. Professor of Medicine Hematopoietic Stem Cell Transplantation Imad A. Tabbara, M.D. Professor of Medicine Hematopoietic Stem Cells Harvested from blood, bone marrow, umbilical cord blood Positive selection of CD34 (+) cells

More information

Vita 34 Parents Guide to umbilical Cord Blood Banking. secure first-class innovative

Vita 34 Parents Guide to umbilical Cord Blood Banking. secure first-class innovative Vita 34 Parents Guide to umbilical Cord Blood Banking secure first-class innovative Contents INTRODUCTION 3 THERAPEUTIC USES OF STEM CELLS 4 STEM CELLS IN CANCER TREATMENT STEM CELLS IN THE TREATMENT OF

More information

Cord blood for the treatment of acute lymphoblastic leukemia in young children

Cord blood for the treatment of acute lymphoblastic leukemia in young children Cord blood for the treatment of acute lymphoblastic leukemia in young children By Caitlin McGreevy Kiara Paramjothy Pass with Merit RESEARCH PAPER BASED ON PATHOLOGY LECTURES AT MEDLINK 2011 1 Abstract:

More information

STEM CELL THERAPEUTIC AND RESEARCH ACT OF 2005

STEM CELL THERAPEUTIC AND RESEARCH ACT OF 2005 STEM CELL THERAPEUTIC AND RESEARCH ACT OF 2005 VerDate 14-DEC-2004 06:53 Jan 05, 2006 Jkt 039139 PO 00000 Frm 00001 Fmt 6579 Sfmt 6579 E:\PUBLAW\PUBL129.109 APPS10 PsN: PUBL129 119 STAT. 2550 PUBLIC LAW

More information

Keeping you in touch with our CordBank community

Keeping you in touch with our CordBank community Safe & safe sound & sound SEPTEMBER 07 Keeping you in touch with our CordBank community We are pleased to bring you some exciting developments, including our new payment plan, enabling more parents to

More information

Stem Cell Transplantation In Patients with Fanconi Anemia

Stem Cell Transplantation In Patients with Fanconi Anemia Stem Cell Transplantation In Patients with Fanconi Anemia FARF Annual Family Meeting 6/28/15 Casco, ME Parinda A. Mehta, M.D. Cincinnati Children s Hospital Medical Center Improvements in Unrelated Donor

More information

Cord Blood: Research Progress and Future Promise

Cord Blood: Research Progress and Future Promise Cord Blood: Research Progress and Future Promise By Al Staropoli, AABB Contributing Writer Sue Fister found out she had leukemia when she was 50 years old. Doctors suggested a bone marrow transplant as

More information

CIGNA HEALTHCARE COVERAGE POSITION

CIGNA HEALTHCARE COVERAGE POSITION CIGNA HEALTHCARE COVERAGE POSITION Subject Umbilical Cord Blood Banking Table of Contents Coverage Position... 1 General Background... 1 Coding/Billing Information... 3 References... 3 Revised Date...

More information

Optional Tests Offered Before and During Pregnancy

Optional Tests Offered Before and During Pregnancy Plano Women s Healthcare Optional Tests Offered Before and During Pregnancy Alpha-Fetoprotein Test (AFP) and Quad Screen These are screening tests that can assess your baby s risk of having such birth

More information

Therapeutic Treatment Options: Chronic Blood Transfusions Bone Marrow Transplantation. Marianne E. McPherson Yee, MD, MSc

Therapeutic Treatment Options: Chronic Blood Transfusions Bone Marrow Transplantation. Marianne E. McPherson Yee, MD, MSc Therapeutic Treatment Options: Chronic Blood Transfusions Bone Marrow Transplantation Marianne E. McPherson Yee, MD, MSc Sickle Cell Treatment Options Supportive Care Newborn Screen PCN Immunizations Education

More information

42 USC 274k. NB: This unofficial compilation of the U.S. Code is current as of Jan. 4, 2012 (see http://www.law.cornell.edu/uscode/uscprint.html).

42 USC 274k. NB: This unofficial compilation of the U.S. Code is current as of Jan. 4, 2012 (see http://www.law.cornell.edu/uscode/uscprint.html). TITLE 42 - THE PUBLIC HEALTH AND WELFARE CHAPTER 6A - PUBLIC HEALTH SERVICE SUBCHAPTER II - GENERAL POWERS AND DUTIES Part I - C.W. Bill Young Cell Transplantation Program 274k. National Program (a) Establishment

More information

Save up to 25% off stem cell banking with Netcells Biosciences

Save up to 25% off stem cell banking with Netcells Biosciences Save up to 25% off stem cell banking with Netcells Biosciences In a unique offering, we have been able to arrange an exclusive offer for medical scheme members with Netcells Biosciences Africa s leading

More information

Disclosures. I have no disclosures.

Disclosures. I have no disclosures. Not Your Own Marrow Jenni Krajewski, MD Clinical Assistant Professor, Rutgers New Jersey Medical School Attending Physician, Pediatric Blood and Marrow Transplantation The Institute for Pediatric Cancer

More information

cord blood 4-1-1230, Off Abids Road, Bogulkunta, Hyderabad 500001. 3-6-282, Opp. Old MLA Qrtrs., Hyderguda, Hyderabad 500029.

cord blood 4-1-1230, Off Abids Road, Bogulkunta, Hyderabad 500001. 3-6-282, Opp. Old MLA Qrtrs., Hyderguda, Hyderabad 500029. Department of Obstetrics cord blood UNIT 1 BOGULKUNTA 4-1-1230, Off Abids Road, Bogulkunta, Hyderabad 500001. UNIT 2 HYDERGUDA 3-6-282, Opp. Old MLA Qrtrs., Hyderguda, Hyderabad 500029. UNIT 3 JUBILEE

More information

Newborn Blood Banking, Inc. P.O. Box 270067 Tampa, Florida 33688 Phone (813) 948-2673

Newborn Blood Banking, Inc. P.O. Box 270067 Tampa, Florida 33688 Phone (813) 948-2673 Please complete the following forms and send them back to us along with the registration fee to register. Once we receive your registration forms and payment, we will send you the collection kit. Mother

More information

NEWS RELEASE. For Immediate Release. For more information, please contact:

NEWS RELEASE. For Immediate Release. For more information, please contact: NEWS RELEASE For Immediate Release For more information, please contact: Charlene Han Singapore Cord Blood Bank Tel: (65) 6394-5017 charlene.han.j.j@scbb.com.sg Singapore Cord Blood Bank records 21 st

More information

The Infinite Potential of Stem Cell Japan s Cord Blood Bank and Transplant

The Infinite Potential of Stem Cell Japan s Cord Blood Bank and Transplant The Infinite Potential of Stem Cell Japan s Cord Blood Bank and Transplant Speech by Dr. Tsuneo A. Takahashi Translated by Stella Wang Japan and the United States are the two most experienced countries

More information

Objectives. Cord Blood. Case 1. Case 1. Case 1. Case 1. To provide a framework for answering a family s questions about cord blood storage.

Objectives. Cord Blood. Case 1. Case 1. Case 1. Case 1. To provide a framework for answering a family s questions about cord blood storage. Cord Blood Should we save the baby s cord blood? Meghan A. Higman, MD, PhD Clinical Assistant Professor of Pediatrics Division of Pediatric Hematology/Oncology Assistant Professor of Oncology Pediatrics

More information

Umbilical Cord Blood Stem Cell Research: The Proof is in the Cord

Umbilical Cord Blood Stem Cell Research: The Proof is in the Cord Cauley O. Gieb Advanced Health Law HLP Article Umbilical Cord Blood Stem Cell Research: The Proof is in the Cord Today advances in science seem to gain the most recognition and support when the subject

More information

APPENDIX B SAMPLE INFORMED CONSENT FORM

APPENDIX B SAMPLE INFORMED CONSENT FORM APPENDIX B SAMPLE INFORMED CONSENT FORM B.1 INFORMED CONSENT TO PARTICIPATE IN A RESEARCH STUDY Umbilical Cord Blood Banking for Transplantation You are being asked to take part in a research study that

More information

Pr Eliane Gluckman, MD, FRCP, Disclosure of Interest: Nothing to Disclose

Pr Eliane Gluckman, MD, FRCP, Disclosure of Interest: Nothing to Disclose Pr Eliane Gluckman, MD, FRCP, Hospital Saint Louis, University Paris- Diderot, France Should Haplo-identical transplantation be preferred to cord blood in patients without a matched donor? Disclosure of

More information

Request an information pack

Request an information pack Request an information pack Please tear off completed form and place in mail box, alternatively please fax this page to 03 9551 2933 I would like to receive an information pack by (please tick one) Email

More information

Saving lives globally through mutual miracles. LifeCord is a public non-profit cord blood bank licensed by the FDA.

Saving lives globally through mutual miracles. LifeCord is a public non-profit cord blood bank licensed by the FDA. Saving lives globally through mutual miracles LifeCord is a public non-profit cord blood bank licensed by the FDA. Donating your baby s cord to a public cord blood bank can save lives globally. You can

More information

Stem Cells and Hope for Patients

Stem Cells and Hope for Patients Stem Cells and Hope for Patients by Maureen Condic, Ph.D. Most Americans know someone afflicted with an incurable medical condition. The possibility of stem cell cures has given hope to many who face such

More information

General Information about Donating Blood Stem Cells

General Information about Donating Blood Stem Cells General Information about Donating Blood Stem Cells This document contains general information about joining the national Registry and donating blood stem cells. You could be the Questions & Answers Paul

More information

Technology Review CORD BLOOD BANKING OCTOBER 2006 HEALTH TECHNOLOGY ASSESSMENT UNIT MEDICAL DEVELOPMENT DIVISION MINISTRY OF HEALTH 019/06

Technology Review CORD BLOOD BANKING OCTOBER 2006 HEALTH TECHNOLOGY ASSESSMENT UNIT MEDICAL DEVELOPMENT DIVISION MINISTRY OF HEALTH 019/06 OCTOBER 2006 CORD BLOOD BANKING Technology Review 0 CORD BLOOD BANKING HEALTH TECHNOLOGY ASSESSMENT UNIT MEDICAL DEVELOPMENT DIVISION MINISTRY OF HEALTH 019/06 Prepared by: Dr Norzakiah Mohd Tahir Assistant

More information

HELP SAVE A LIFE DONATE YOUR CORD BLOOD

HELP SAVE A LIFE DONATE YOUR CORD BLOOD HELP SAVE A LIFE DONATE YOUR CORD BLOOD University Hospitals of Leicester Anthony Nolan Cord Blood Donation Programme Did you know that following the safe birth of your baby, you could save a person s

More information

TM SM www. genecell.com

TM SM www. genecell.com TM SM www.genecell.com Why is umbilical cord blood so special? Umbilical cord blood is a rich source of stem cells, which may potentially help your baby and your family from numerous diseases. There are

More information

GENETIC COUNSELORS KNOWLEDGE AND PERSPECTIVES OF CORD BLOOD BANKING AND STEM CELL THERAPIES

GENETIC COUNSELORS KNOWLEDGE AND PERSPECTIVES OF CORD BLOOD BANKING AND STEM CELL THERAPIES GENETIC COUNSELORS KNOWLEDGE AND PERSPECTIVES OF CORD BLOOD BANKING AND STEM CELL THERAPIES A Research Project Presented to the Faculty of California State University, Stanislaus In Partial Fulfillment

More information

Pediatric Cord Blood Transplantation Webcast August 27, 2008 Colleen Delaney, M.D. M.Sc. Introduction

Pediatric Cord Blood Transplantation Webcast August 27, 2008 Colleen Delaney, M.D. M.Sc. Introduction Pediatric Cord Blood Transplantation Webcast August 27, 2008 Colleen Delaney, M.D. M.Sc Please remember the opinions expressed on Patient Power are not necessarily the views of Seattle Cancer Care Alliance,

More information

MEDICAL COVERAGE POLICY

MEDICAL COVERAGE POLICY Important note Even though this policy may indicate that a particular service or supply is considered covered, this conclusion is not necessarily based upon the terms of your particular benefit plan. Each

More information