FMD SITUATION IN TURKEY. -Country Report- FMD SITUATION IN TURKEY. - Country Report- Dr Nihat Pakdil Deputy Secretary of M.A.R.A.

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1 Appendix 11 FMD SITUATION IN TURKEY -Country Report- FMD SITUATION IN TURKEY - Country Report- Dr Nihat Pakdil Deputy Secretary of M.A.R.A. of Turkey A.Naci BULUT Head of Diagnosis Department Sap Institute, Ankara, Turkey Introduction Turkey has been endemic with FMD (Type O and A) FMD field strains in Turkey A Iran 5 Endemic in Anatolia since November 5 New variant of type O PanAsia Endemic in Anatolia since October 6 Asia 1 No case since 2 NO DISEASE OCCURRED IN THRACE REGION SINCE 7 EuFMD 77 th Executive Committee 1

2 Current Disease Situation NUMBER OUTBREAKS 7-NOV NO. OF OUTBREAKS JA JA FE MA AP MA JU JU AU SE OC NO DE FE MA AP MA JU JU AU SE OC NO N N B R R Y NE LY G PT T V C B R R Y NE LY G PT T V 7 8 TYPE O TYPE A UNTYPED Disribution of outbreaks Type A:136 Type O:47 Untyped:51 Current Disease Situation After the two big endemic, 6 type A and 7 type O; the first time no peak recorded this year after the Kurban Festival As a result: number of outbreak has been declined sharply Outbreaks due to the type A relatively were increased begining the this year; now seems in peace Outbreaks due to the type O were decrease first and after the disappearing during the summer time, it has been shifted with new exotic sub-variant(4% genetic differencess) on August Mainly distributed in Erzincan and Erzurum Index case is Erzincan Diease was occurred in young unvaccinated or primmovaccinated population At the moment disease has not been extend in range; clustering in east region because of very well vaccination coverage EuFMD 77 th Executive Committee 2

3 Genetic and antigenic diversities Type O seems still stable antigenicly O1 Manisa vacc. Strain covers antigenicly Geneticly new O Pan-Asia sub-strain (Group IIA) However, latest O isolates are part in a new group with 4% difference geneticly from former group Type A5 Iran has been changed in time Genetic lineage take places two groups -the latest one almost 5% far from previous;5ard 7 Antigenic poor reaction with A22 Iraq vacc. r values: <.2 a new sub-strain; A Tur 6 Policy on the combating of the disease For the combating FMD in Turkey; Vaccination, Slaughtering (in Thrace region only); bio-security measures (Quarantine, disinf., anm. movement control so on) Control policy is based mainly vaccination This year a project has been started for three years: EU Project (Control of Foot and Mouth Disease (FMD) in Turkey Project no: TR 6 3 2) EuropeAid Project (124939/D/SUP/TR( /D/SUP/TR) for control of FMD in Turkey GOAL Control of FMD in Turkey by mass vaccination policy in accordance with other EU control measures such as animal identification, movement and market controls. Total Budget: Duration: 3 Years End Date: November 1 Activities Vaccination Sero-survey Cleaning and Disinfection EuFMD 77 th Executive Committee 3

4 The Project First step tender for vaccine supply was completed by CFCU for supplying Spring 8 vaccine Contract signed with the FMD Institute (5.2.8), Merial (12.2.8) and Intervet (3.1.8) Delivery of vaccines between Vaccine dilevered for Spring 8 FIRMS Vacc. for SR Vacc. for LR Amount of vacc.tendered Supplied Amount of vacc.tendered Supplied Intervet Merial Şap Enstitüsü As a total, ( bivalent; trivalent) for large rum and (1.5. bivalent; trivalent) for small rum. 8 Spring vaccination scheme All bovine animals population has been vaccinated twice a year. (~ 1.3 mil. Dosesx2) EuFMD 77 th Executive Committee 4

5 VACCINATION COVERAGE FOR SPRING 8 for cattle TRACE VACC. COVERAGE CATTLE SMALL RUM SPRING VACC. COVERAGE FOR CATTLE (BY REGIONS) 8 MEDITERIA INNER MARMARA EGEAN N ANATOLIA BLACK SEA EAST SOUTH ANATOLIA EAST ISTANBUL ÇANAKKALE EDIRNE KIRKLARELI TEKIRDAG Seri REGIONS : 85- % : - 85 % : 5- % VACCINATION COVERAGE FOR CATTLE BY REGION MARMARA REGION MEDITERIAN REGION EAGEAN REGION PE RCE NTAGE 8 BILEC IK BU R SA C AN AKKALE ED IR N E ISTAN BU L KIR KLAR ELI S KOC AELI SAKAR YA TEKIR D AG YALOVA P E RC E N T AG E 8 T O T AL AD AN A AN T ALYA BU R D U R H AT AY ISPAR T A S M ER SĐN K.M AR AS O SM AN IYE PE RCENTAGE 8 AYDIN BALIKESIR D EN IZ LI IZ M IR KU TAHYA S M ANISA M U GLA U SAK BLACK SEA REGION INNER ANATOLIA REGION 1 8 DÜZCE KARABÜK BARTIN ZONGULDAK SINOP SAMSUN ORDU RIZE KASTAMONU GUMUSHANE S GIRESUN BOLU TRABZON ARTVIN AMASYA BAYBURT 1 8 AFYONKARAHĐSAR ANKARA CANKIRI CORUM ESKISEHIR KAYSERI KIRIKKALE KONYA NEVSEHIR NIGDE S SIVAS TOKAT YOZGAT AKSARAY KARAMAN KIRSEHIR EAST ANATOLIA REGION SOUTH EAST REGION 1 8 ARDAHAN IGDIR VAN TUNCELI MUS MALATYA KARS ELAZIG ERZINCAN ERZURUM BINGOL BITLIS AGRI 1 8 KILIS SIRNAK S.URFA SIIRT MARDIN HAKKARI GAZIANTEP DIYARBAKIR ADIYAMAN S S 8 Spring vaccination scheme Small ruminants population has been vaccinated partially(<1/3), because of shortage of supplied vaccine:1.5 million doses bivalent and mil. Doses trivalent (Whole population size: ~3 mil. TURKEY VACC. COVERAGE FOR SMALL RUM. (BY REGIONS) 8 MARMARA EAGEN INNER ANATOLIA REGIONS EAST ANATOLIA SOUTH EAST ANATOLIA EuFMD 77 th Executive Committee 5

6 VACCINATION COVERAGE FOR SMALL RUM. BY REGION VACC. COVERAGE IN EAGEN (SR) VACC. COVERAGE IN MARMARA (SR) ISTANBUL KOCAELI SAKARYA BĐLECIK BURSA YALOVA ÇANAKKALE TEKIRDAĞ EDIRNE KIRKLARELI IZMIR BALIKESIR AFYON AYDIN DENIZLI MUĞLA UŞAK KÜTAHYA VACC. COVERAGE IN INNER ANATOLIA (SR) VACC. COVERAGE IN EAST ANATOLIA (SR) ANKARA KONYA AKSARAY NĐĞDE NEVŞEHIR KAYSERĐ SĐVAS KIRŞEHIR KIRIKKALE KARA MAN ESKIŞEHIR YOZGAT ERZURUM KARS ARDAHAN IĞDIR AĞRI ERZINCAN ELAZIĞ MALATYA TUNCELĐ BĐNGÖL MUŞ BĐTLĐS VAN VACC. COVERAGE IN SOUTH EAST (SR) DIYARBAKIR URFA G.ANTEP MARDIN HAKKARĐ BATMAN ŞIRNAK KĐLĐS SĐĐRT ADIYAMAN Second phase tenders for vaccine supply Vaccine for Autumn 8: Vaccine was supplied by tender: 6.. doses doses : 7.312M Contract for vacc. will be signed end of the June Those supplied vaccines were delivered between July and October 8 Vaccine delivery scheme for Autumn 8 CATTLE POP BIV TRIV TAR% VACC. REM FROM SPRING DEMAND SUPPLIED DEFICIT Addition to this suppliment; Sap Institute provided 35. doses during the campaign THRACE* MARMARA (Thrace not incl.)) EAGEAN MEDITERIAN (Hatay not incl.)) INNER ANATOLIA BLACK SEA (Artvin not incl.) EAST ANATOLIA (excluding border prov.) SOUTH EAST ANATOLIA (excluding border prov.) BORDER % 9% 9% 9% 9% 85% 9% 9% 9% EuFMD 77 th Executive Committee 6

7 VACCINATION COVERAGE FOR AUTUMN 8 TURKEY VACC. COVERAGE FOR CATTLE (BY REGIONS) P E R C E N TA G E M A R M A R A EA G E N M E D IT E R IA N IN N E R A N A T O L IA BLACK SEA REGIONS E A S T A N A T O L IA S O U T H E A S T A N A T O L IA T O T A L TRACE VACC. COVERAGE CANAKKALE EDIRNE ISTANBUL TEKIRDAG KIRKLARELI VACCINATION COVERAGE FOR CATTLE BY REGION VACC COVERAGE IN MEDITERIAN VACC. COVERAGE IN EAGEN 8 ADANA ANTALYA BURDUR HATAY ISPARTA MERSĐN K.MARAS OSMANIYE 8 IZMIR AYDIN BALIKE KUTAH DENIZLI MUGLA MANIS USAK AFYON SIR YA A Seri Seri VACC. COVERAGE IN MARMARA VACC. COVERAGE IN INNER ANATOLIA ISTANBUL KOCAELI SAKARYA BĐLECIK BURSA YALOVA 8 ÇANAKKAL KIRKLARE TEKIRDAĞ EDIRNE E LI Seri ANKAR CANKI ESKISE KAYSE KIRSE NEVSE NIGDE YOZGA AKSAR KARAM KIRIKK SIVAS KONYA A RI HIR RI HIR HIR T AY AN ALE Seri VACCINATION COVERAGE FOR CATTLE BY REGION(2) VACC. COVERAGE IN BLACK SEA 8 DÜZ AMA ART BOL COR GIRE GUM KAST ORD RIZE SAM SINO TOK CE SYA VIN U UM SUN USH AMO U SUN P AT TRA ZON BAY BAR KAR TOTA BZO GUL BUR TIN ABÜ L Seri VACC. COVERAGE IN EAST ANATOLIA VACC. COVERAGE IN SOUTH EAST 8 ARDAH IGDIR VAN TUNCE MUS KARS ELAZIG ERZIN ERZUR BINGO AGRI BITLIS MALAT AN LI CAN UM L YA 8 GAZIANT DIY ARBA ADIY AMA KILIS BATMAN SIRNAK S.URFA SIIRT MARDIN HAKKARI EP KIR N Seri Seri EuFMD 77 th Executive Committee 7

8 Biosecurity measures Mass vaccination has been conducted just before the festival This campaign will be gain high protection rate just before the fes. Vacc. Campaign: September-November/Fes.: 8-11 December A new notification has been published to encourage high range vaccination coverage Province in which recording less than 85 % coverage will be compansate by banning animal movement outside/in Task and action force has been established for the Kurban festival in each big cities Animal movement has been regulated by: Notification specific for movement before and after festival It has been carried out restriction on animal movement: unvaccinated animal not allowed; not vaccinated animal has to vaccinate before the movement at least 14 days Biosecurity measures A specific notification has been published for arrangement impermanent animal market in Istanbul and Thrace region Notification is described: Design of market in Istanbul; separate market regarding to origin of animals each Thrace and Anatolia Unsold animals; Unsold Animals from Istanbul market will not be allowed for returning back to Thrace; will be slaughtered in its place In case of moved to another place; 3 weeks quarantine will be conducted in place which final destination of animals Biosecurity measures Notification to Governorships of Istanbul/Thrace and Municipalities of Istanbul/Thrace Regional meeting with participation of state /municipality vet services, governorships, municipalities, police and stakeholders will be held to asses all dispositions for preparedness It will be conducted preventive measures at animal markets and slaughterhouses Regularly disinfection will be carried out at specific places State and Municipalities vet services will work with coordination to inspect all measures; A training for owners and dealers will be conducted In order to enhance awareness of the situation, it has been prepared booklets,notices and posters EuFMD 77 th Executive Committee 8

9 SEROSURVEILLANCE ACTIVITIES Serosurveillance was designed in Anatolia; aimed: To estimate NSP prevalance To asses vacc. Effectiveness and ab prevalance Sera were collected during the Autumn campaign; NSP: 33.9 Ab : 3.78 Testing has been delay, because of delay on the tender for ELISA kits Result will be available on January 9, using Institute s kits SEROSURVEILLANCE ACTIVITIES (THRACE) It was initiated a program with 3 years aimed to substantiate free of FMD with vaccination As a first year activities: Active surveillance has been initiated Well structured control measurres has been implemented Serosurveillance has been conducted NSP prevalance: Vaccine effectiveness: 9 Testing will be carried out after the supplied kits by tender: March-may 9 EuFMD 77 th Executive Committee 9