CURRICULUM VITAE. Jason Yamaki, Pharm.D., Ph.D.



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CURRICULUM VITAE Jason Yamaki, Pharm.D., Ph.D. Personal Information Business Address Chapman University School of Pharmacy 9401 Jeronimo Road Irvine, CA, 92618 Telephone 714-516-5482 E-mail address yamaki@chapman.edu Academic Work Experience: 5/2014 Present Research Assistant Professor and Assistant Director of Assessment Chapman University, School of Pharmacy 1/2014 4/2014 Assistant Professor of Clinical Sciences American University of Health Sciences, School of Pharmacy Education: 2009 2013 Doctor of Philosophy, Clinical and Experimental Therapeutics Department of Clinical Pharmacy and Pharmaceutical Economics and Policy University of Southern California, Los Angeles, California 2005 2009 Doctor of Pharmacy Department of Clinical Pharmacy and Pharmaceutical Economics and Policy University of Southern California, Los Angeles, California 2002 2005 Bachelors of Science, Microbiology Department of Biology California State University Dominguez Hills, Carson, CA 1998 2000 Santa Monica College, Santa Monica, CA Licensure: 2009 - Present California State Board of Pharmacy, RPH 63347 Pharmacy Work Experience: 2005-2008 Intern Pharmacist, Rite-Aid Pharmacy 2000-2005 Pharmacy Clerk, Rite-Aid Pharmacy

Research Work Experience: 2007-2009 Research Assistant, Anti-Infective Pharmacology Lab University of Southern California, School of Pharmacy (PI; Annie Wong-Beringer) 2009-2013 Post-doctoral Ph.D. Candidate Clinical and Experimental Therapeutics University of Southern California, School of Pharmacy Department of Clinical Pharmacy and Pharmaceutical Economics and Policy Research Skills: ELISA, gel electrophoresis, reverse transcription-pcr, PCR, cell culture, mouse handling and experimentation, western blotting, basic microbiology techniques, bacterial cloning, neutrophil isolation, database management and statistical analysis Research Interests 1) Bacterial toxins/virulence factors and their mechanisms of actions 2) Patient outcomes and molecular epidemiology research 3) Bacterial Pathogenesis Didactic Teaching Activity: 2014 Present Clinical Trials Masters of Science, Pharmaceutical Sciences Chapman University, School of Pharmacy 2014 2014 Pathophysiology Masters of Science Program in Clinical Research American University of Health Sciences 2009 2013 Teaching Assistant Doctor of Pharmacy Curriculum Pharmacy experience module: supervised and instructed in the vaccination laboratories, conducted calculation breakout sessions, and supervised compounding laboratories Public Health course: Supervisor and preceptor at health fairs 2009 - Present Lecturer - Infectious Disease, Therapeutics Module VII University of Southern California, School of Pharmacy Didactic Topics: MRSA Infections; Clostridium difficile infections 2012-2013 Lecturer Pharmacokinetics, Therapeutics Module II Didactic Topic: Pharmacokinetics, pharmacodynamics, and clinical calculations of vancomycin

Previous/Current Laboratory Trainees: 2014 Priyanka Rughwani (M.S. student) 2013 Joyce Bensman (Ph.D. student) Nadine Musallam (Pharm.D. candidate) Joyce Ho (Pharm.D. candidate) Muanil Desai (M.D.) 2012 Edward Brauer (Pharm.D. candidate) 2011 Katherine Bang (Pharm.D. candidate) 2009 Albert Nguyen (M.D. candidate) Honors, Certifications, Awards: 2013 USC Clinical and Translation Science Institute pilot study award (Co- Investigator) 2012 USC School of Pharmacy Best Research Assistant Award 2012 USC School of Pharmacy Best Teaching Assistant Award 2010 American Society for Microbiology (ASM), Infectious Disease Fellow Travel Grant 2008 USC Graduate Summer Research Fellowship 2008 American Society for Microbiology (ASM), Student Travel Grant 2005 - Present Certified Immunization Provider 2003-2005 Deans List, California State University Dominguez Hills Professional Associations: 2014 Present Society of Infectious Disease Pharmacists 2014 Present American Association of Colleges of Pharmacy 2010 2012 Member-in-Training, Infectious Disease Society of America 2010 Present Member, American College of Clinical Pharmacy 2009 Present Member, California Pharmacists Association 2002 Present Member, American Society for Microbiology Chapman University Service 2014 Present Chapman University Assessment Committee 2014 Present Chapman University Institutional Biosafety Committee Chapman School of Pharmacy Service 2014 Present Academic Affairs Committee 2014 Present Graduate and Research Program Committee

2014 Present Pharmacy Practice Search Committee Publications (Peer-reviewed) 1) Jason Yamaki, Michelle Lee, Kimberly A. Shriner, Annie Wong-Beringer: Can clinical and molecular epidemiologic parameters guide empiric treatment with vancomycin for methicillin-resistant Staphylococcus aureus infections? Diagn Microbiol Infect Dis. 2011 May;70(1):124-30 2) Jason Yamaki, Timothy Synold, Annie Wong-Beringer: Anti-virulence Potential of TR- 700 and Clindamycin on Clinical Isolates of Staphylococcus aureus producing Phenol- Soluble Modulins. Antimicrobial Agents and Chemotherapy, 2011 Sept;55(9):4432-5 3) Jason Yamaki, Timothy Synold, Annie Wong-Beringer: Tigecycline induction of phenol soluble modulins by invasive MRSA strains. Antimicrobial Agents and Chemotherapy, 2013 Sept;57(9):4562-4565 4) Jason Yamaki, Emi Minejima, Paul Nieberg, Annie Wong-Beringer: Molecular epidemiology and clinical outcomes associated with in-vitro lung epithelial cell cytotoxicity and production of protein A and α-hemolysin among MRSA isolates causing community-onset pneumonia. (Manuscript in preparation) 5) Julianne Joo, Jason Yamaki, Mimi Lou, Shenche Hsieh, Tony Chu, Kimberly Shriner, Annie Wong-Beringer: Early response assessment to guide management of Methicillin- Resistant Staphylococcus aureus bloodstream infections with vancomycin therapy. Clinical Therapeutics, 2013 July; Vol. 35 (7), 995-1004 6) Kenneth P. Tai, Karishma Kamdar, Jason Yamaki, Valerie V. Le, Dat Tran, Patti Tran, Michael E. Selsted, André J. Ouellette, Annie Wong-Beringer; Microbicidal effects of α- defensins against Vancomycin Resistant MRSA and Ciprofloxacin Resistant Pseudomonas aeruginosa (Innate Immunity, 2013 Dec, Epub) 7) Joyce Bensman, Martin Tuan Tran, Rosemary She, Emi Minejima, Jason Yamaki, Joyce Ho, Paul Nieberg, Jennifer Cupo, Annie Wong-Beringer. Early cytokine balance predicts persistent Staphylococcus aureus bacteremia and mortality. (Manuscript submitted, Journal of Antimicrobial Chemotherapy 2014) 8) Mok T. Chong, Jason Yamaki, Megan Harwood, Richard d Assalenaux, Ettie Rosenberg, Okezie Aruoma, Anupam Bishayee; Assessing health conditions and medication use among the homeless community in Long Beach, California. (Journal of Research in Pharmacy Practice 2014;3:56-61) 9) Jason Yamaki, Anupam Bishayee; Health-promoting and disease-preventive potential of Trianthema portulacastrum Linn. (Gadabani) an Indian medicinal and dietary plant (Manuscript in preparation) Abstracts

1. Jason Yamaki, Michelle Lee, Kimberly Shriner, Annie Wong-Beringer; PVL (+) MRSA Causing Infections in Hospitalized Patients 18th Annual European Congress of Clinical Microbiology and Infectious Disease (ECCMID) 2008, Barcelona, Spain. (Poster) 2. Jason Yamaki, Annie Wong-Beringer; Vancomycin Susceptibility of Infected MRSA Strains Based on Clinical, Epidemiological and Microbiologic Variables 48th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy, Washington D.C, USA. (Poster) 3. Julianne Joo, Orquidea Rogers, Jason Yamaki, Mimi Lou, Kimberly Shriner, Annie Wong-Beringer; Factors Predictive of Treatment Failure of MRSA Bloodstream Infections 49th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) Sep. 2009, San Francisco, USA. (Platform) 4. Julianne Joo, Orquidae Rogers, Jason Yamaki, Kimberly Shriner, Annie Wong- Beringer. Contribution and associated outcomes of Community MRSA strains in bloodstream infections 49th Annual Interscience Conference on Antimicrobial Agents of Chemotherapy, San Francisco, Sep. 2009 (Poster) 5. Jason Yamaki, Annie Wong-Beringer; Effects of Sub-inhibitory concentrations of TR- 700 on Phenol-Soluble Modulin Production in MRSA 50th Annual Interscience Conference on Antimicrobial Agents of Chemotherapy, Boston, Sept 2010 (Poster) 6. Jason Yamaki, Julianne Joo, Orquidae Rogers, Kimberly Shriner, Annie Wong- Beringer. Community Associated MRSA Strains in Bloodstream Infections and Associated Outcomes Annual Infectious Diseases Pharmacotherapy Fellowship Forum, Aspen, May 2010 (Platform) 7. Emi Minejima, Jason Yamaki, Paul Nieberg, Annie Wong-Beringer; Molecular Epidemiology of Community-Onset Pneumonia caused by MRSA and Associated Clinical Features 51st Annual Interscience Conference on Antimicrobial Agents of Chemotherapy, Chicago, Sept 2011 (Poster) 8. Jason Yamaki, Timothy Synold, and Annie Wong-Beringer A. Effects of antibiotic exposure on methicillin-resistant Staphylococcus aureus virulence expression. American Society of Microbiology 112 th General Meeting, San Francisco, June 2012. (Poster) 9. Jason Yamaki, Emi Minejima, Joyce Ho, Edward Brauer, Paul Nieberg, Annie Wong- Beringer. Disease severity associated with in-vitro production of alpha-hemolysin and Protein A in MRSA isolates causing community-onset pneumonia. 53rd Annual Interscience Conference on Antimicrobial Agents of Chemotherapy, Denver, Sept 2013 (Poster) 10. Emi Minejima, Jason Yamaki, Paul Nieberg, Annie Wong-Beringer. Epidemiology and outcomes of MRSA with high vancomycin MIC causing community-onset pneumonia. 53rd Annual Interscience Conference on Antimicrobial Agents of Chemotherapy, Denver, Sept 2013 (Poster) 11. Joyce Bensman, Martin Tuan Tran, Rosemary She, Emi Minejima, Jason Yamaki, Joyce Ho, Paul Nieberg, Jennifer Cupo, Annie Wong-Beringer. Early cytokine balance predicts persistent Staphylococcus aureus bacteremia and mortality. 53rd Annual

Interscience Conference on Antimicrobial Agents of Chemotherapy, Denver, Sept 2013 (Platform) References Annie Wong-Beringer, PharmD Vice Chair, CPPEP, USC School of Pharmacy Mok T. Chong, PharmD, PhD, MBA Department Chair, American University of Health Sciences James Ito, MD Infectious Diseases Section Chair, City of Hope Medical Center