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International Symposium Controversies in Endocrine Surgery and Translational Research Bergen, August 23 rd 24 th, 2012 Radisson Blu Royal Hotel, Bryggen www.bergenendocrine2012.no

Welcome Dear friends and colleagues, A very warm welcome to the Capital of the Fjords! It is our honor and pleasure to have you here during the International Symposium on Controversies in Endocrine Surgery and Translational Research. The Haukeland University Hospital has a long tradition and high expertise in Endocrine Surgery which is dated back to the early 1970-ies when Peter Heimann, one of the founders of the International Association of Endocrine Surgeons, established a Section for Breast and Endocrine Surgery which was the first in. Endocrine Surgery is a developing and changing specialty. During this conference we will discuss the chances for cooperation with basic science (translational research), the future challenges regarding competition with other specialties, and current controversies concerning diagnosis and treatment of diseases within the field of Endocrine Surgery. We hope you will enjoy a stimulating conference, our beautiful city and the fantastic nature in our country. Turid Aas, MD, Surgeon in Chief Jan Erik Varhaug, MD, PhD Michael Brauckhoff, MD, PhD

General Information The conference will be held under the auspices of: Norwegian Society of Breast and Endocrine Surgery European Society of Endocrine Surgeons (ESES) International Association of Endocrine Surgeons (IAES) Scientific committee: Prof. Michael Brauckhoff, MD, PhD Prof. Jan Erik Varhaug, MD, PhD Turid Aas, MD and Faculty of Medicine and Dentistry Department of Surgery Jonas Lies vei 69 N-5021 Bergen Organization: Kongress & Kultur AS Torgalmenningen 1A Postboks 947 Sentrum N-5808 Bergen T: + 47 55 55 36 55 F: + 47 55 55 36 56 mail@kongress.no www.kongress.no Congress venue: Radisson Blu Royal Hotel, Bryggen Bryggen 5 N-5835 Bergen T: +47 55 54 30 00 F: +47 55 32 48 08 sales.bgozh@radissonblu.com Registration/Information: Please register at: http://www.bergenendocrine2012.no For more information please contact: mail@kongress.no

General Information Congress fee: Until June 30 th 2012: 2800 NOK (ca. 350 ) From July 1 st 2012: 3300 NOK (ca. 410 ) Welcome Reception: By the Mayor of the City of Bergen Wednesday, August 22 nd 2012, 7:00 pm Schøtstuene, Øvregaten 50, N-5003 Bergen http://www.museumvest.no Start from the hotel: 6:50 pm. 5 min walk to the venue. Complimentary Congress Dinner: Thursday, August 23 rd 2012 Fløien Folkerestaurant i Bergen http://www.bellevue-restauranter.no Fee (including Fløibanen funicular roundtrip): 500 NOK (ca. 65 ) Fløien is one of the most impressive attractions in Bergen. Accommodation: Please register at: http://www.bergenendocrine2012.no For more information please contact: mail@kongress.no Exhibition: Please visit the congress exhibition. The exhibition is open from Thursday, August 23 rd 2012, 08:30 a.m.

Thursday, 23.08.2012 Scientific program 08:30-09:30 Registration Opening of the Exhibition 09:30 10:00 Opening Welcome Remarks Jan Erik Varhaug, Bergen, Stener Kvinnsland, Bergen, Leiv M. Hove, Bergen, August M. Bakke, Bergen, Turid Aas, Bergen, 10:00 10:30 Endocrine Surgery in Bergen Jan Erik Varhaug, Bergen, 10:30 11:00 Coffee Break Please visit the congress exhibition 11:00 12:30 Session I: Translational Research in Breast and Endocrine Surgery What is the future? Rolf Kåresen, Oslo, Johan Lillehaug, Bergen, 11:00 11:25 The role of molecular biology for personalized cancer treatment Anne Lise Børresen-Dale, Oslo, 11:25 11:50 The principles of drug resistance in oncology Per Eystein Lønning, Bergen, 11:50 12:15 Principles in drug design The role of N-acetyltransferase in thyroid cancer Thomas Arnesen, Bergen, 12:15 12:30 The role of the surgeon in translational research Jan Erik Varhaug, Bergen, 12:30 13:30 Lunch

Thursday, 23.08.2012 Scientific program 13:30 15:00 Session II: Translational Research Göran Akerström, Uppsala, Sweden Jan Erik Varhaug, Bergen, 13:30 13:50 Why do parathyroid adenomas not sense calcium properly? John A. Olson Jr, Baltimore, USA 13:50 14:15 MEN 1 genotypes and phenotypes in Eystein Husebye, Bergen, 14:15 14:40 Multiple Endocrine Neoplasia type 2 The integrated DNA-based/biochemical concept Henning Dralle, Halle, Germany 14:40 15:00 Hereditary pheochromocytoma Hartmut P. Neumann, Freiburg, Germany 15:00 15:30 Coffee Break Please visit the congress exhibition 15:30 16:15 Key lecture Jan Erik Varhaug, Bergen, Michael Brauckhoff, Bergen, Mechanisms of Growth and Spread of Differentiated Thyroid Cancer Orlo H. Clark, San Francisco, USA

Thursday, 23.08.2012 Scientific program 16:15 17:45 Session III: The future of Endocrine Surgery Robert Udelsman, New Haven, USA Henning Dralle, Halle, Germany 16:15 16:40 The education in Endocrine Surgery Anders Bergenfelz, Lund, Sweden 16:40 17:00 The role of robotic surgery Laurent Brunaud, Nancy, France 17:00 17:20 The role of ENT in Endocrine Surgery Jan Olofsson, Bergen, 17:20 17:45 National Programs The Turkish experience Bahadır Güllüoğlu, Istanbul, Turkey 19:00 Dinner

Friday, 24.08.2012 Scientific program 08:15 09:30 Session IV: Thyroid Nodule Lars A. Akslen, Bergen, Bruno Niederle, Vienna, Austria 08:15 08:35 Ultrasound, FNAC, Elastography - Differential diagnosis in thyroid nodules Martin Biermann, Bergen, 08:35 08:55 Markers with potential clinical significance Lars A. Akslen, Bergen, 08:55 09:15 Calcitonin screening Bruno Niederle, Vienna, Austria 09:15 09:30 Thyroid incidentalomas - treatment and/or follow-up? Svante Jansson, Göteborg, Sweden 09:30 10:00 Coffee break Please visit the congress exhibition 10:00 11:30 Session V: Differentiated thyroid cancer Orlo H. Clark, San Francisco, USA Henning Dralle, Halle, Germany 10:00 10:30 What is low risk thyroid cancer and how to treat? Robert Udelsman, New Haven, USA 10:30 11:00 Surveillance after radioiodine treatment Christoph Reiners, Würzburg, Germany 11:00 11:30 Treatment of iodine negative metastases in differentiated thyroid cancer Lars Bastholt, Odense, Danmark 11:30 12:30 Lunch

Friday, 24.08.2012 Scientific program 12:30 13:50 Session VI: Primary hyperparathyroidism (PHPT) Bertil Hamberger, Stockholm, Sweden Jan Erik Varhaug, Bergen, 12:30 12:50 Treatment options in asymptomatic HPT Jan Bollerslev, Oslo, 12:50 13:10 Surgical strategies in familial PHPT Per Hellman, Uppsala, Sweden 13:10 13:30 How to treat recurrent PHPT? Jean Francois Henry, Marseille, France 13:30 13:50 PHPT and bone density Peer Christiansen, Aarhus, Danmark 13:50 14:20 Coffee break Please visit the congress exhibition 14:20 15:50 Session VII : Adrenals / NET Jan Francois Henry, Marseille, France Hartmut P. Neumann, Freiburg, Germany 14:20 14:40 Controversies in the diagnosis and management of primary aldosteronism Bertil Hamberger, Stockholm, Sweden 14:40 14:55 Subtotal adrenalectomy: When and how? Michael Brauckhoff, Bergen, 14:55 15:10 Rationale of follow up in adrenal incidentaloma Bo Wängberg, Göteborg, Sweden 15:10 15:30 The diversity of gastrointestinal NET Andrea Frilling, London, UK 15:30 15:50 Screening and indication to surgery in MEN 1 and VHL patients with pancreatic NET Göran Akerström 15:50 Closing Remarks

Speakers and moderators Aas, Turid Akerström, Göran Akslen, Lars Andreas Arnesen, Thomas Bakke, August Bastholt, Lars Bergenfelz, Anders Biermann, Martin Bollerslev, Jan Brauckhoff, Michael Brunaud, Laurent Børresen-Dale, Anne-Lise Christiansen, Peer Clark, Orlo H Dralle, Henning Frilling, Andrea Gullüglo, Bahadir Hamberger, Bertil University Hospital Uppsala Department of Pathology, Department of Molecular Science, University of Bergen Department of Oncology, University Hospital Odense University Hospital Lund Department of Nuclear Medicine, Department of Internal Medicine, University Hospital Oslo University Hospital Nancy Department of Molecular Science, University of Oslo University Hospital Aarhus University of California, San Francisco University Hospital Halle Department of Surgery and Cancer, Imperial College London Marmara University Istanbul Karolinska University Hospital Stockholm Sweden Denmark Sweden France Denmark USA Germany United Kingdom Turkey Sweden

Speakers and Hellman, Per Henry, Jean Francois Hove, Leiv M Husebye, Eystein Jansson, Svante Kvinnsland, Stener Kåresen, Rolf Lillehaug, Johan Lønning, Per Eystein Neumann, Hartmut Niederle, Bruno Olofsson, Jan Olson Jr., John A Reiners, Christoph Udelsman, Robert Varhaug, Jan Erik Wängberg, Bo University Hospital Uppsala University Hospital Marseille Department of Surgical Sciences, University of Bergen Department of Internal Medicine, Sahlgrenska University Hospital Gothenburg CEO University Hospital Oslo Department of Molecular Science, University of Bergen Department of Oncology, Department of Internal Medicine, University Hospital Freiburg University Hospital Vienna Department of ENT, University of Maryland, Baltimore Department of Nuclear Medicine, University Hospital Wurzburg Yale University Hospital New Haven Sahlgrenska University Hospital Gothenburg Sweden France Sweden Germany Austria USA Germany USA Sweden

Thank you to our sponsors AstraZeneca Bayer AS Condor Dr. Langer GSK Johnson&Johnson Medistim / Medtronic AB Novartis Nycomed Olympus Europa Roche Norge AS