ADVANCED HEMATOLOGY - COURSE SYLLABUS

DEPARTMENT OF LABORATORY SCIENCES AND PRIMARY CARE CLINICAL LABORATORY SCIENCE PROGRAM AHLC 4242 SPRING 2015 ADVANCED HEMATOLOGY - COURSE SYLLABUS Instructor Joel D. Hubbard, Ph.D., MT(ASCP) 1

COURSE SYLLABUS AHLC 4242 COURSE TITLE: AHLC 4242, Advanced Hematology COURSE DESCRIPTION: This course provides students with the fundamentals of pathological disorders of the red blood cell (erythrocyte) and white blood cell (leukocyte) systems. The main focus of this course will be the disease processes involving RBCs and WBCs, how these diseases are identified clinically, and the laboratory characteristics of each disorder. The course will be divided into three major units: l) Pathophysiology of RBC disorders; 2) Pathophysiology of granulocytic and monocytic disorders; 3) Pathophysiology of lymphocyte disorders. INSTRUCTOR INFORMATION: Instructor: Joel D. Hubbard, MT(ASCP), PhD Department of Laboratory Sciences and Primary Care Clinical Laboratory Science Program Phone: 806-743-3256 E-mail: joel.hubbard@ttuhsc.edu CREDIT HOURS: 2 COURSE TEXTBOOKS: Required: Hubbard, Joel D. A Concise Review of Clinical Laboratory Science, Lippincott Williams & Wilkins, 2 nd edition, 2009, ISBN 978-0-7817-8202-9. Carr JH, Rodak BF. Clinical Hematology Atlas. Elsevier Saunders, 4 rd Ed., 2013. ISBN: 978-1-4557-0830-1 COURSE COMPETENCY OBJECTIVES: During this semester of Advanced Hematology (AHMT 4242) we will build upon the basics of hematology you learned last semester, with a study of various hematological disorders that affect red blood cells, white blood cells, or both. The competency objectives of the course are designed to expose the student to the pre-analytical, analytical, and post-analytical components of hematological pathophysiology and hematological testing. A list of the Objectives for each topic can be found in each Weekly Overview document that accompanies each Lecture Module. IT IS VERY IMPORTANT THAT YOU FIRST READ THE WEEKLY OVERVIEW AND OBJECTIVES BEFORE CONTINUING WITH THE LECTURE MODULE CONTENTS. 2

Upon completion of AHMT 4242, it is required that the student demonstrates, at a minimum level of 70%, the following competencies: 1. Assimilate the knowledge necessary to understand which lab tests are necessary to perform in order to diagnosis a hematological disorder. 2. Build a firm foundation and working knowledge of anemias and related pathophysiology and an understanding of the laboratory characteristics of each. 3. The ability to be able to distinguish between different pathological types of anemia and polycythemia based on the patient s case history and lab reports. 4. The ability to be able to categorize different pathological types of nonmalignant WBC disorders based on the patient s case history and lab reports. 5. The ability to be able to distinguish between different pathological types of leukemia and lymphoma based on the patient s case history and lab reports. 6. The knowledge to evaluate a patient s case history and accompanying lab results, and form a reasonable differential diagnosis. 7. The skills necessary to construct a case study and present it in a clear and concise format. 8. The professionalism to demonstrate ethical behavior and maintain confidentiality of patient results. SPECIFIC LECTURE OBJECTIVES: Objectives for each lecture topic are listed for each lecture within the Learning Modules icon on the course Sakai web page. SAKAI: THE HUB To aid you in review and learning and because we all have different learning styles, a WEB site has been created for this course. There you will find the following study aids: 1. A printable copy of the course syllabus with course schedules 2. A Weekly Overview document with each Lecture Module providing a summary of the material, objectives, important dates, and how to successfully proceed with the week s material. 3. Copies of the Power Point lectures with audio along with printable note copies of each lecture 4. ipod lecture format of each lecture. 5. Learning Modules laying out what needs to be done each week and what assignments and exams are due. 6. Practice exams 7. assignments 3

8. A mode to E-mail the instructor with any questions assignments (must be handed in in Microsoft Word format ONLY). No other formats will be accepted. 9. Discussion treads designed to allow students to ask the instructor about specific lecture, homework, or exam information, and allow answers to be made public to all students. (Forum icon) 10. Related web links for additional study and information To access the HUB go the following address shown below: http://elearn.ttuhsc.edu You must have an E-raider username and password to gain access. Once you log in, simply select which course you want to access from the next page. All HUB weekly course module contents (i.e., lectures and homework assignments) will be released Sunday morning of the new week at 7:00am CST. Homework assignments will be due the following week after the module is released by Tuesday at 12:00 noon Central Standard Time (CST). Exams will be released on Thursday morning at 12:01am CST and will have a deadline of submission by the following Tuesday at 12:00 noon CST. All due date times will be in Central Time (CST). Please note: Faculty members are not required to have access to TTUHSC or Sakai email after work hours on week days or on the weekend. If you send an email to the program or faculty member during this period of time, the response may be delayed until they return to work Monday morning. Also, some faculty do not have access to email while performing clinic duties and this may delay responses as well. EVALUATION OF STUDENT LEARNING: The reading requirements from your text (see course schedule) are an important part of your being able to understand and learn hematology, and should be completed BEFORE completing each lecture module. Several sets of s assignments, and practice exams covering the material presented will be provided throughout the semester to aid you in your learning process. I encourage you to complete and review them as a study method. Examinations: There will be 12 HUB-based integrative review exams, and one comprehensive final examination over lecture material. The comprehensive final exam will be administered as a proctored exam. Exam format will include multiple choice, matching and true/false questions. Material to be covered will include questions over lecture topics, textbook material, and any other information provided. Once graded, examinations will be reviewed and any questions will be addressed as necessary. All students are expected to take all examinations and the final examination on the scheduled dates and times. Students are expected to abide by the Code of Professional and Academic Conduct in taking their exams without the aid of notes, other students, or open textbooks. Weekly Exams for this course will be posted on Webct Thursday at 12:01am CST on the week of the assigned Lecture Module and close on Tuesday of the next week at 12:00 noon CST. Each exam will be timed at 30 minutes. Exam grades and exam review will not be available until all students have taken the exam and the exam deadline has passed. Please notify the instructor and the faculty coordinator of any illness or emergency that would conflict with taking an examination. 4

Graded exams will be released for review each Tuesday afternoon from 2:00pm CST to 8:00pm CST to the entire class. EXAMS CANNOT BE RELEASED FOR REVIEW TO STUDENTS ON AN INDIVIDUAL BASIS AT ANY OTHER TIME BECAUSE OF SOFTWARE LIMITATIONS. Taking of exams with open class notes, the Internet, or other students taking the course is considered a violation of academic misconduct and the Code of Professional and Academic Conduct document that you signed. All exams are property of the CLS Program and are not to be printed or copied for personal use. Violation of this policy will constitute academic misconduct and may lead to suspension. s: Eleven assignments will be given throughout the semester. This assignment will be found under the Assignment Component of the course HUB web page and are intended to both assess student learning and participation. Each lecture module will contain a set of s that will consist of 5-10 questions. Each assignment is worth 2% of your total course grade. Assignments will be posted each Sunday of the new Lecture Module at 7:00am CST and will be due by Tuesday of the following week by 12:00 noon CT. Any student who fails to submit a assignment within the allotted time will receive a grade of 0% for each assignment. ALL STUDY QUESTION HOMEWORK ASSIGNMENTS MUST BE TURNED IN IN MICROSOFT WORD FORMAT. ANY OTHER FORMATS (pdf, jpeg, ect) ARE UNACCEPTABLE AND WILL NOT BE GRADED. Course Grades: You will receive the grade you earn. Your final grade will consist of an average grade your weekly exams, homework assignments, and the final exam. YOUR AVERAGE COURSE GRADE SHOULD BE 70% OR HIGHER IN ORDER TO PASS THIS CORE COURSE. Any course with an average grade of less than 70% is considered a "D" in that course. Any course with a component having a grade of less than 60% is considered an "F" in that course. Grades will be posted on the online Grade Book component in a timely manner. Earning a "D" or lower in any CLS course may result in repeating the course or dismissal from the program. METHOD OF EVALUATION: Exams 12 @ 2.5% each 30% Final Exam 04/20 04/25 48% Homework Assignments 11 @ 1.5% each 22% The grading scale for the course will be as follows: A 90-100 B 80-89.9 C 70-79.9 D 60-69.9 F <60.0 5

Student Conduct Each student should be familiar with his or her responsibilities regarding class conduct and academic honesty as described in the School of Allied Health Sciences Catalog and the Department of Laboratory Sciences and Primary Care Clinical Laboratory Science Program Student Handbook. This Handbook can be accessed at the following website address: http://www.ttuhsc.edu/sah/current/handbooks.aspx All students are expected to exhibit professional conduct in the chat rooms and discussion areas of Webct and laboratory setting. Any student wishing to discuss these aspects of professional conduct with the course instructor is encouraged to do so. Academic Integrity: Professionals are expected to practice with a commitment to high standards and integrity. The development of this commitment begins during academic training. Academic misconduct is considered to be an act contrary to professional ethics, and includes, but is not limited to taking exams with class notes or other Internet sites, or other forms of cheating such as; plagiarism, falsification of records, and any and all other actions that may distort evaluation of a student's academic performance or achievement, assisting others in such acts, or attempting to engage in such acts. In addition, copying weekly and final exam questions with the intent to share exam questions with other students is considered a serious violation of academic misconduct and could lead to dismissal from the course or program. Refer to the School of Allied Health Sciences Catalog and the Department of Laboratory Sciences and Primary Care Student Handbook for additional information. Computer/Internet Problems: Students must have contingency plans for computer and Internet problems. Some suggestions include becoming familiar with Internet/free PC usage within your community, or seeking out friends, family, and even coworkers who have Internet services. It is your responsibility to have a backup plan for PC and Internet failure. PC and Internet failure is not a blanket excuse to turn in late assignments and not participating in the discussion process. PC and internet failure is not a blanket excuse for missing exams or turning in late assignments and not participating in the discussion process. For computer, internet, and online Sakai problems, call or e-mail problems to our CLS/MP IT guy: Mr. Frank Mack 806-743-2274 frank.mack@ttuhsc.edu 6

Software Requirement: Microsoft Office 2007 or newer. If you do not have Microsoft Office 2007 or newer installed, you will have problems downloading or viewing the Syllabus. For $10, a copy of Microsoft Office 2010 can be purchased via the following address: https://www.ttuhsc.edu/it/is/itsolutioncenter/media/purchase. Further instructions can be found on the following page http://www.ttuhsc.edu/it/is/itsolutioncenter/media/ under the heading "Purchase Software Media (for personal use)". Additionally, the Mac version (Office 2011) can be downloaded at https://eraider.ttu.edu, Special Accommodations: The University is committed to the principle that in no aspect of its programs, shall there be differences in the treatment of persons because of race, creed, national origin, age, sex, or disability and that equal opportunity and access to facilities shall be available to all. If you require special accommodations in order to participate, please contact the instructor at 743-3256 or by e-mail to joel.hubbard@ttuhsc.edu. Students should present appropriate verification from the Office of Student Services. No requirement exists that accommodations be made prior to completion of this approved University process. Syllabus: The student is responsible for reading, understanding and abiding by the contents of this syllabus. If the requirements of this course are not understood, it is the responsibility of the student to contact the instructor for clarification within one week of receiving this syllabus. The Instructor and Program is not responsible for the student missing due dates and receiving poor grades because of failure to read required documents such as the Student Handbook or Course Syllabus. The syllabus must be read and affirmed before student will be allowed access into all parts of the course s SAKAI HUB components. 7

AHLC 4242 FOUNDATIONS OF HEMOSTASIS COURSE SCHEDULE SPRING 2015 WEEK/DATE Week 1; 01/12 01/17 Week 2; 01/18 01/24 Week 3; 01/25 01/31 Week 4; 02/01 02/07 Week 5; 02/08 02/14 TOPIC (exam deadline) Module 1a: Stem Cell Disorders of RBCs; Part 1 Module 1b: Stem Cell Disorders; Part 2 Module 1c: Stem Cell Disorders; Part 3 Weekly Exam #1; (Released; 1/15) (Due; 1/20) Module 2a: Heme Disorders ; Part 1 Module 2b: Heme Disorders; Part 2 Weekly Exam #2 (Released; 1/22) (Due; 1/27) Module 3a: Globin Chain Disorders; Part 1 Module 3b: Globin Chain Disorders; Part 2 Module 3c: Globin Chain Disorders; Part 3 Weekly Exam #3 (Released 1/29) (Due; 2/03) Module 4a: Globin Chain Disorders; Part 4 Module 4b: Globin Chain Disorders; Part 5 Weekly Exam #4 (Released; 2/05) (Due; 2/10) Module 5a: DNA Disorders; Part 1 Module 5b: DNA Disorders; Part 2 Weekly Exam #5 (Released; 2/12) (Due; 2/17) HOMEWORK Assignment 1 (Due 1/20) Assignment 2 (Due 1/27) Assignment 3 (Due 2/10) Assignment 4 (Due 2/17) READINGS Text pg. 117-125 Text pg. 125-131 Text pg. 131-138 Text pg. 138-142 8

Week 6; 02/15 02/21 Week 7: 02/22 02/28 Week 8: 03/01 03/07 Week 9: 03/08-03/14 Module 6a: Survival Disorders; Part 1 Module 6b: Survival Disorders; Part 2 Module 6c: Survival Disorders; Part 3 Weekly Exam #6 (Released; 2/19) (Due; 2/24) Module 7a: Qual. & Quan. WBC Disorders; Part 1 Module 7b: Qual. & Quan. WBC Disorders; Part 2 Module 7c; Qual. & Quan. WBC Disorders; Part 3 Weekly Exam #7 (Released; 2/26) (Due; 3/03) Module 8a: Intro. to Leukemias and Cytochem. Stains; Part 1 Module 8b: Intro. to Leukemias and Cytochem. Stains; Part 2 Weekly Exam #8 (Released; 03/5) (Due; 3/10) Module 9a: Chronic Myeloid Leukemias; Part 1 Module 9b: Chronic Myeloid Leukemias; Part 2 Module 9c; Chronic Myeloid Leukemias; Part 3 Weekly Exam #9 (Released; 03/12) (Due; 03/17) Assignment 5 (Due 2/24) Assignment 6 (Due 3/03) Assignment 7 (Due 3/10) Assignment 8 (Due 03/17) Text pg. 142-145 Text pg. 145-153 Text pg. 154-156 Text pg. 157-161 SPRING BREAK (03/13 3/21) Week 10; 03/22 03/28 Module 10a: Acute Myeloid Leukemias; Part 1 Module 10b: Acute Myeloid Leukemias; Part 2 Weekly Exam #10 (Released; 03/26) (Due; 3/31) Assignment 9 (Due 3/31) Text pg. 161-163 9

Week 11; 03/29-04/04 Week 12; 04/05-04/11 Module 11a: Lymphocyte Maturation and Structure Module 12a: Lymphocyte Nonmalignant Disorders; Part 1 Module 12b; Lymphocyte Nonmalignant Disorders; Part 2 Module 12c; Lymphocyte Nonmalignant Disorders; Part 3 Weekly Exam #11 (Released; 04/02) (Due; 04/07) Module 13a: Lymphocytic Leukemias; Part1 Module 13b: Lymphocytic Leukemias; Part 2 Module 14a: Lymphomas Weekly Exam # 12 (Released; 04/09) (Due; 04/14) Assignment 10 (Due 4/07) Assignment 11 (Due 4/14) Text pg. 164-170 Text pg. 171-176 04/20-04/25 FINAL EXAMS Proctored Finals due back by 04/27/13 10