ICA-Symposium Summer 2014



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ICA-Symposium Summer 2014 Organized by ICA, supported by the Priority Program BioScience and Health, the Departments of Cell Biology, Molecular Biology and Organismic Biology, and the FP7 Program HUMUNITY 30 th of June 1 st of July 2014, Unipark Nonntal, Erzabt Klotz Strasse 1, Salzburg Opening: Monday 30 th of June, 9:00, Lecture Hall Anna Bahr-Mildenburg (E.004) Monday, 30 th of June 9:00 Welcome: Josef Thalhamer Chair: Ulrike Berninger and Raimund Tenhaken 9:15 10:00 Understanding and Predicting Impacts on the Ocean Through Studies of Marine Microbiology Dave Caron Dana and David Dornsife College University of South California USA 10:00 10:15 Matthias Hötzinger Title: Genetic and ecophysiological diversity in Polynucleobacter and Limnohabitans bacteria Supervision: Martin Hahn and Ulrike Berninger 10:15 10:30 Carmen Abfalter Title: Bacterial proteases Supervision: Silja Weßler and Fritz Aberger

10:30 10:45 Thomas Schmidt Title: Functional role of E-cadherin in Helicobacter pylori-associated carcinogenesis Supervision: Silja Weßler and Fritz Aberger 10:45 11:00 Robert Behmüller Title: The role of arabinokinase for carbon supply of plant cells Supervision: Raimund Tenhaken and Roland Reischl 11:00 11:15 Kathrin Mikkeleit Title: The role of UGD for cell wall sugar synthesis in Arabidopsis thaliana Supervision: Raimund Tenhaken and Anja Geretschläger 11:15 11:30 Coffee break Chair: Hans Brandstetter and Hanno Stutz 11:30 11:45 Shihui Guo Title: Biochemical characteristics of prostatic KLKs Supervision: Hans Brandstetter and Peter Goettig 11:45 12:00 Han Fang Title: Human blood coagulation Factor VIII expression, purification and characterization Supervision: Hans Brandstetter and Thomas Zögg 12:00-12:15 Julia Fegg Title: Biochemical and Structural Characterization of Biosimilar Variants Supervision: Hans Brandstetter and Gabriele Gadermaier 12:15 12:30 Lorenz Stock Title: Protein disulphide bond changes revealed by capillary electrophoresis Supervision: Hanno Stutz 12:30 14:00 Lunch break Chair: Peter Eckl and Christian Huber 14:00 14:45 Oxidized proteins in chronic disease: how to detect them and why they are important Corinne Spickett School of Life & Health Sciences Aston University, Aston Triangle Birmingham, UK

14:45 15:00 Caroline Hecklau Title: Application of L-cysteine derivatives in animal cell culture to enhance solubility and stability Supervision: Peter Eckl and Jörg von Hagen 15:00 15:15 Lavinija Matakovic Title: Cofactor deficiency in mitochondrial diseases Supervision: Johannes Mayr and Barbara Kofler 15:15 15:30 Florian Füssl Title: Investigation of the mechanism of action of the neurotrophic drug Cerebrolysin Supervision: Christian Huber and Roland Reischl 15:30 15:45 Coffee break Chair: Hans-Christian Bauer and Ludwig Aigner 15:45 16:00 Richard König Title: Physiology of Cellular Plasticity in the Adult Brain Supervision: Hans Christian Bauer and Ludwig Aigner 16:00 16:15 Simona Lange Title: CNS-Pericytes - A Crucial Role in Remyelination? Supervision: Hans Christian Bauer and Ludwig Aigner 16:15 16:30 Stefanie Kortner Title: The influence of nutrition on tendon quality and regeneration Supervision: Hans Christian Bauer and Alois Lametschwandtner 16:30 16:45 Angela Zissler Title: Effects of extracorporal shockwave treatment on skeletal muscle tissue Supervision: Alexandra Sänger and Peter Steinbacher 16.45 17:00 Stefan Pittner Title: Degradation of skeletal muscle post mortem Supervision: Peter Steinbacher and Fabio Monticelli 17:00 17:15 Martin Ruggenthaler Title: Impurity profiling of pharmaceuticals Supervision: Christian Huber and Josefine Grass 17:15 17:30 Michaela Haider Title: Ultra-sensitive detection of mrna in a pancreatic cancer cell line Supervision: Fritz Aberger and Jan Hesse

Tuesday, 1 st of July 9:00 Welcome Chair: Richard Weiss and Gabriele Gadermaier 9:15 10:00 Protective environmental factors for the development of asthma and allergies Erika von Mutius Dr. von Hauner Children s Hospital Ludwig Maximilian University Munich Germany 10:00 10:15 Teresa Stemeseder Title: Influences of environmental triggers and lifestyle on the development of allergic sensitizations Supervision: Fatima Ferreira and Gabriele Gadermaier 10:15 10:30 Almedina Isakovic Title: The natural immune response against the grass pollen allergen Phl p 5 in non-atopic humans Supervision: Richard Weiss and Josef Thalhamer 10:30 10:45 Yoan Machado Title: Modulation of immune responses against Bet v 1 by glycoconjugation Supervision: Josef Thalhamer and Richard Weiss 10:45 11:00 Martin Wolf Title: Purification and characterization of immunologically relevant isoforms of the major ragweed allergen Amb a 1 Supervision: Fatima Ferreira and Michael Wallner 11:00 11:15 Stephanie Eichhorn Title: A Pru p 3 proline variant: a promising candidate for treatment of LTP-related food allergy? Supervision: Fatima Ferreira and Gabriele Gadermaier 11:15 11:30 Coffee break Chair: Jutta Horejs-Höck 11:30 11:45 Theresa Neuper Title: Negative regulation of IL-6 and IL-10 mediated STAT3 activation by NOD1 and Jutta Horejs-Höck

11:45 12:00 Leon Pradel Title: 'Heterogeneity and Targeting of CSF-1R in Tumor-Associated Macrophages Supervision: Cornelia Hauser-Kronberger, Josef Thalhamer and Carola Ries (Roche, Penzberg, Germany) 12:00-12:45 Persistent Vector-based Strategies for Infectious Disease & Cancer Michael Jarvis School of Biomedical & Healthcare Sciences University of Plymouth UK 12:45 14:00 Lunch break Chair: Stefan Dötterl and Robert Junker 14:00 14:45 The evolution of hummingbirds and their nectar plants Susanne Renner Department of Biology Ludwig Maximilian Universtity Munich Germany 14:45-15:00 Simon Lehner Title: The mystery of the butterfly bush: How are the butterflies attracted? plant Supervision: Stefan Dötterl and Ulrike Berninger 15:00 15:15 Anne-Amélie Larue Title: Functional and phylogenetic diversity of plant communities in consideration of flower visitors sensory physiology Supervision: Robert Junker and Stefan Dötterl 15:15 15:30 Annemarie Heiduk Title: Fly fooling flowers - The amazing pollination ecology of Ceropegia Supervision: Stefan Dötterl and Ulrich Meve 15:30 15:45 Jonas Kuppler Title: Exploring the personalities of plants - effects of intra-specific trait variation on individual fitness Supervision: Robert Junker and Klaus Lunau 15:45 16:00 Coffee break

Chair: Albert Duschl and Iris Gratz 16:00 16:15 James Gavigan Title: HUMUNITY - Developing predictive models for human gut and airways mucosae 16:15 16:30 Elfi Töpfer Title: HUMUNITY - The role of innate leukocytes in advanced mucosal co-culture models 16:30 16:45 Gergo Sipos Title: HUMUNITY - Epithelial cells in physiological relevant mucosal in-vitro models 16:45 17:00 Mariusz Madej Title: HUMUNITY - Mimicking human mucosae: how to find the appropriate architecture 17:00 17:15 Christina Ramsauer Title: Differential proteomics of stimulated dendritic cells using HPLC-MS Supervision: Christian Huber and Josef Thalhamer 17:15 17:30 Douglas Pinheiro Title: Investigation of the mechanisms underlying peripheral regulatory T cell generation Supervision: Josef Thalhamer and Iris Gratz End of the Symposium