LIFE SCIENCES QUEENSLAND LIMITED (LSQ) Mario Pennisi

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Molly Holt
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1 LIFE SCIENCES QUEENSLAND LIMITED (LSQ) Mario Pennisi

2 LEADING DESTINATION FOR CLINICAL RESEARCH INVESTORS IN QLD INCLUDE:

3 LIFE SCIENCES IN QLD ~300 companies in life sciences ~$5B invested by the Queensland Government Queensland is a proven innovation powerhouse: Gardasil, the world s first cervical cancer vaccine Picato, the first topical therapy to treat actinic keratosis Nanopatch, next generation needle-free vaccine delivery Prof Maree Smith (Spinifex/Novartis) The Excellence in Research for Australia (ERA) report shows the QLD research leads the nation

therapy to treat actinic keratosis Nanopatch, next generation needle-free vaccine delivery Prof Maree Smith

4 GROWING SCIENTIFIC LINKS BETWEEN QLD AND ASIA

5 29 GOVERNMENT FUNDED BIOTECHNOLOGY RESEARCH INSTITUTES Institute for Molecular Bioscience (1999) Institute for Glycomics (2000) Institute of Health & Biomedical Innovation (2002) Australian Institute for Bioengineering & Nanotechnology (2002) Institute for Cellular & Molecular Therapies ESKITIS (2003) Queensland Animal Breeding Facility (2003) Mater Medical Research Institute (2003) Wesley Research Institute Clinical Research Centre (2003) Centre for Marine Microbiology & Genetics Research (2003) Centre for Integrated Preclinical Drug Development (2004) Queensland Crop Development Facility (2004) Centre for Advanced Animal Science (2004) Medical Engineering Research Facility (2004) Wesley Research Institute Tissue Bank (2005) Queensland Compound Library (2005) UQ Centre for Clinical Research (2005) Queensland Brain Institute (2005) Bionano products Development Facility (2006) Medical Diagnostics Technologies in QLD (2006) Mackay Renewable Biocommodites Pilot Plant (2006) Australian Tropical Science and Innovation Precinct (2006) Wesley Research Institute Health and Medical Research Centre (2006) Translational Research Institute (2006) Ecosciences Precinct (2007) Health and Food Sciences Precinct (2007) Molecular and Clinical Pathology Research Laboratory (2008) Queensland Tropical Health Alliance (2008) Queensland Institute of Medical Research (2008) Australian Institute for Tropical Health and Medicine (2012)

Research Institute Clinical Research Centre (2003) Centre for Marine Microbiology & Genetics Research (2003) Centre for Integrated Preclinical Drug Development (2004) Queensland Crop Development

6 SCIENCE INFRASTRUCTURE Translational Research Institute Biopharmaceuticals and vaccination research and translation QIMR Berghofer Medical Research Institute Cancer, infectious diseases, mental health and range of complex diseases Australian Institute for Bioengineering and Nanotechnology Protein engineering, drug delivery and environmental nanotechnology Patheon Biologics a leading global contract manufacturing service provider for monoclonal antibodies and recombinant proteins expressed in mammalian cell lines.

Institute for Bioengineering and Nanotechnology Protein engineering, drug delivery and environmental nanotechnology Patheon

7 SCIENCE INFRASTRUCTURE Institute for Molecular Bioscience Genetics research and personalised medicines Queensland Brain Institute Sensory systems, neural research and epigenetics Institute of Health and Biomedical Innovation Wound research, injury prevention and chronic disease research Gold Coast University Hospital A 750 bed teaching hospital colocated with Griffith University opened Q3 2013

Health and Biomedical Innovation Wound research, injury prevention and chronic disease research

8 SCIENCE INFRASTRUCTURE Australian Institute of Tropical Health & Medicine (AITHM) Biosecurity and tropical infectious diseases, genomics and cancer research Centre for Tropical Crops and Biocommodities Working on biofortification of bananas for sub- Saharan Africa (Bill & Melinda Gates Foundation Funding) ESKITIS Institute for Cellular & Molecular Therapies Attracted $100M investment by AstraZeneca Established Nature Bank of samples plant and marine invertebrate species and Natural Product Fractions ~ 600,000 compounds ready to screen Home to Compounds Australia Queensland Alliance for Agriculture and Food Innovation Working with DAFF to address problems for sorghum growers across the world s low rainfall regions (Bill & Melinda Gates Foundation Funding)

investment by AstraZeneca Established Nature Bank of samples plant and marine invertebrate species and Natural Product Fractions ~ 600,000 compounds ready to screen Home to Compounds

9 LEADING DESTINATION FOR CLINICAL RESEARCH INVESTORS IN QLD INCLUDE: WHY? Access world calss R&D High-quality clinical facilities with state-of-the-art equipment for testing and analysis A fast, pragmatic regulatory pathway and reciprocal arrangements with regulatory authorities such as the FDA and EMA Strong intellectual property protection Generous R&D tax incentives (43.5%) Ethnically diverse patient cohorts Well-characterised tissue banks, for use in precursor studies Counter-seasonality with the northern hemisphere

regulatory pathway and reciprocal arrangements with regulatory authorities such as the FDA and EMA Strong intellectual property

LSQ MEANS BUSINESS FOR MEMBERS 174 Member organisations Human Healthcare (pharmaceuticals / drug delivery, complementary medicines, functional foods / beverages, medical devices, diagnostics) 143

10 LSQ MEANS BUSINESS FOR MEMBERS 174 Member organisations Human Healthcare (pharmaceuticals / drug delivery, complementary medicines, functional foods / beverages, medical devices, diagnostics) 143 headquartered in Queensland Foreign Members from USA, UK, Germany, Singapore, China and India Animal Health Agriculture Environmental Biotechnology Industrial Biotechnology (Bio-energy, Bio-mining) Marine Biotechnology

headquartered in Queensland Foreign Members from USA, UK, Germany, Singapore, China and India Animal

11 REASONS TO WORK WITH LSQ Take advantage of Australia s 43.5% R&D tax credit Access streamlined CTN/CTX schemes for regulatory approval Work with a coordinated, comprehensive peak industry organisation to facilitate introductions to leading Australian business entities Work closely with State and Federal government to assist the sector and promote the role of innovation in economic development Host key industry events such as I-20 and TABBS Leveraging $20b Medical Research Future Fund Leveraging $185m Advance Queensland plan

organisation to facilitate introductions to leading Australian business entities Work closely with State and Federal government to

HOST OF INNOVATION-20 In 2014 LSQ put innovation on the agenda by hosting the inaugural I-20 summit in Brisbane during the G20 Leaders Summit LSQ is working with the Republic of Turkey who have

12 HOST OF INNOVATION-20 In 2014 LSQ put innovation on the agenda by hosting the inaugural I-20 summit in Brisbane during the G20 Leaders Summit LSQ is working with the Republic of Turkey who have incorporated I-20 into the official program of G , through T-20 Speakers at I included: - Josh Lerner, Harvard Business School - James C Greenwoood, BIO - Jack Bobo, US Department of State

have incorporated I-20 into the official program of G20 2015, through T-20 Speakers at I-20 2015

13 TABBS OCTOBER 12, 2015 The Australian Bioenergy and Bioproducts Symposium (TABBS) Realising the Bioeconomy - It's Hot in the Tropics! Monday 12th October 2015 Brisbane Convention and Exhibition Centre, Brisbane, Australia

14 INTERNATIONAL PARTNERS

15 THANK YOU TO OUR SUPPORTERS

2019 Healthcare That Works for All

2019 Healthcare That Works for All This paper is one of a series describing what a decade of successful change in healthcare could look like in 2019. Each paper focuses on one aspect of healthcare. To