Midwinter Conference 2015 January Seefeld, Tyrol CONFERENCE PROGRAM. midwinter2015.org. Sponsored by

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1 Midwinter Conference 2015 January Seefeld, Tyrol CONFERENCE PROGRAM Sponsored by

2 SATURDAY, 17 January Keynote lecture Richard Flavell Sponsored by Welcome Reception Hosted by SUNDAY, 18 January METABOLISM Manipulation of microbiota and inflammatory Dan Littmann lymphocytes in autoimmune disease New York University Diet and immunity Hermann Wagner Technische Universität München Regulatory T cells and cancer Alexander Rudensky Memorial Sloan-Kettering Cancer Center Novel therapies for diabetes and obesity Mathias Tschoep Helmholtz Center, Technische Universität München TBD Marc Veldhoen University of Cambridge CANCER TYK2-STAT1-BCL2 pathway dependence in Thomas Look T-cell acute lymphoblastic leukemia Cytokine signaling blockade with Jak inhibitors José-Carlos Gutierrez-Ramos in patients Pfizer Molecular mechanism of tolerance to dead cells Peter Krammer German Cancer Research Center (DKFZ)

3 The activities of E- and Id-proteins in immune Cornelis Murre homeostasis University of California, San Diego Cell cycle machinery in development and in Peter Sicinski cancer How to model human lymphomas in mice? Klaus Rajewsky Max Delbrück Center, Berlin Antibodies, Genome Stability, and Cancer Frederik Alt Poster Session / Discussion Rounds Fingerfood will be served MONDAY, 19 January The role of Pax5 in B cell leukemia Meinrad Busslinger Research Institute of Molecular Pathology, Vienna Cell competition and T cell leukemia Hans-Raimer Rodewald German Cancer Research Center (DKFZ) Viral mimics of epigenetic regulators Alexander Tarakhovsky Rockefeller University Immune checkpoint blockade in cancer Jim Allison therapy: New insights and opportunities MD Anderson Arms race in cancer treatment; giving T cells a Stefan Endres help Ludwig-Maximilians University, Munich

4 Cancer therapy by T-cell engaging antibodies Patrick Bäuerle Amgen / Ludwig-Maximilians University, Munich Genome-wide analysis of Notch function in Taras Kreslavsky T cell development Research Institute of Molecular Pathology, Vienna Dissecting immune responses to tumors Philippe Bousso using in vivo imaging Institut Pasteur, Paris Poster Session / Discussion Rounds Fingerfood will be served TUESDAY, 20 January AUTOIMMUNITY TBD Stefan Meuer University of Heidelberg The Helios transcription factor as guardian Harvey Cantor of self-tolerance Enhancing the effectiveness of vaccines by Ken Shortman targeting vaccine antigens to dendritic cells Walter & Eliza Hall Institute, Melbourne Immune tolerance in human autoimmune Carolin Daniel Type 1 Diabetes Helmholtz Center, Munich Central tolerance to autoantigens of the CNS Ludger Klein Ludwig-Maximilians University, Munich T cell subsets in immunity, autoimmunity Federica Sallusto and allergy Institute for Research in Biomedicine, Bellinzona

5 Autoimmune bowel disease Fiona Powrie University of Oxford Immunological phenomena in vascularized Stefan Schneeberger / tissue transplantation Raimund Margreiter University of Innsbruck Poster Session / Discussion Rounds Fingerfood will be served WEDNESDAY, 21 January RORgt+ lymphoid cells in intestinal immunity Gerard Eberl Institut Pasteur, Paris TBD Thomas Brocker Ludwig-Maximilians University, Munich DRUG DISCOVERY TBD Lukas Huber Oncotyrol, Innsbruck Developmental pathways of broadly Antonio Lanzavecchia neutralizing antibodies and autoantibodies Institute for Research in Biomedicine, Bellinzona Human antibodies for HIV prevention and Michel Nussenzweig therapy Rockefeller University, New York Camelid anibodies as novel tool Hidde Ploegh Whitehead Institute, Boston

6 SHORT TALKS Short Talks 6 x 15 minutes Short Talks 6 x 15 minutes Farewell Reception

7 Sponsors