cell signaling research antibodies and sirna gene silencers



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santa cruz biotechnology, inc. The Power to Question cell signaling research antibodies and sirna gene silencers SEE OUR WEB SITE FEATURING: 7,426 monoclonal antibodies 19,542 polyclonal antibodies 13,269 sirnas and support products HEADQUARTERS EUROPEAN SUPPORT ASIAN SUPPORT TEL: 831.457.3800 TEL: +49.6221.4503.0 JAPAN TOLL FREE: (010) 800.40402026 TOLL FREE: 1.800.457.3801 TOLL FREE: +00800.4573.8000 S. KOREA TOLL FREE: 00798.1.1.002.0297 FAX: 831.457.3801 FAX: +49.6221.4503.45 CHINA TOLL FREE: 10.800.711.0752 or EMAIL: scbt@scbt.com EMAIL: europe@scbt.com 10.800.110.0694 EMAIL: asia@scbt.com 2006-2007 Santa Cruz Biotechnology, Inc., all rights reserved. "Santa Cruz Biotechnology" and the Santa Cruz Biotechnology, Inc. logo are registered trademarks of Santa Cruz Biotechnology, Inc.

Amazing! INNOVATION @ WORK Over 4,000 high quality antibodies from a single source Sigma s AMAZING collection of high quality antibodies: Includes monoclonals, polyclonals, secondaries, conjugates and custom services Validated using a variety of methods WB, IHC, IF, IP, ELISA Easily explored through Sigma s award-winning online tools Supported by Sigma s world-renowned technical service to assist you with your specific antibody requirements Search for your antibody of interest using these convenient online tools at sigma.com/antibody Antibody Explorer Gene ID Search PathFinder Your Favorite Gene Search matches your gene of interest to thousands of Sigma antibodies Sigma is your source. Go to sigma.com/antibody and be Amazed! sigma.com/yfg sigma.com Accelerating Customers Success through Leadership in Life Science, High Technology and Service SIGMA-ALDRICH CORPORATION BOX 14508 ST. LOUIS MISSOURI 63178 USA

Regulatory Reagents from ebioscience CD4 + CD25 hi GITR + CD127 dim mouse CD127: A7R34 (cat#1271) human CD127: ebiordr5 (cat#1278) CD127-Alexa Fluor 647 (cat# 51-1278) Human PBMCs CD127-APC (cat# 17-1271) Mouse Splenocytes Foxp3 Foxp3-PE (cat# 12-4777) CD4-FITC (cat# 11-0041) PDCA-1 TGF-β Human PBMCs Mouse Splenocytes DC ILT7 Foxp3-PE (cat# 72-5776) Foxp3-PE (cat# 72-5775) Siglec H CD25-APC (cat# 17-0259) CD25-APC (cat# 17-0251) As understanding of the complexity of the regulatory T cell/dendritic cell interaction has grown, ebioscience leads the way with a comprehensive panel of critical new reagents to speed discovery in regulatory cell research. New Tools for Treg and DC Research: Dendritic cells ILT7 (pdc), PDCA-1, CMKLR1, Siglec H, DCIR, DC-LAMP, DC-SIGN, DEC-205, 33D1, CCR7, CD11c, CD46, CD83, CRACC, Langerin, Notch, TLR9, TSLP Receptor Regulatory T cells TGF-β1, Foxp3, AITR/GITR and ligands, CD46, CD62L, CD103, CD127, CTLA-4, LAG-3, Neuropilin, CD73 Additional new reagents: IC Flow IL-1β, IFN-α2, IL-13, IL-17A, Granzyme B, Granulysin, Perforin, T-bet ELISA IL-13, IL-15, IL-17A, IL-21, IL-23, IL-29/IFN-λ, LAG-3, TGF-β1, TSLP Use code 7AAI to receive a gift with purchase. * Visit us at AAI booth #410 or visit www.ebioscience.com for the latest products. *While supplies last. For end users only. One offer per lab. Alexa Fluor and Pacific Blue are registered trademarks of and licensed under patents assigned to Molecular Probes, Inc. for research use only. WEB www.ebioscience.com ORDER 888.999.1371 FAX 858.642.2046 TECH 888.810.6168 TECH SUPPORT tech@ebioscience.com INQUIRIES contact@ebioscience.com

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I work for St. Joseph s Children s Hospital of Tampa, because it works for me! This is your opportunity to join St. Joseph s Children s Hospital of Tampa! PH.D. Tampa, FL The Division of Oncology at St. Joseph s Children s Hospital of Tampa, a member of the BayCare Health System family, is seeking a full-time Ph.D. with recent laboratory training and experience in immunology and molecular genetics. Start up research funds, competitive salary and benefits provided. Interested candidates may send CV to: Heather Thomas, Team Resources St. Joseph s Children s Hospital 3003 W. Dr. Martin Luther King Jr. Blvd. Tampa, FL 33607 Fax: 813-870-4813 E-mail: heather.thomas@baycare.org EOE/DFWP HISTOCOMPATABILITY SPECIALISTS Temple University Hospital (Philadelphia, PA) is seeking Histocompatability (HLA) Specialists to join our HLA Laboratory. Job duties include high complexity HLA serological testing including antigen typing, antibody screening and identification, flow cytometry and molecular typing and donor-recipient crossmatching procedures. BS/BA degree in Molecular Biology or a related field required. Please send CV to Steven Kim at kimsj@tuhs.temple.edu.

The New PHAD in Vaccine Technology Avanti s Synthetic Vaccine Adjuvant PHAD Avanti Number 699800 Vaccination is well-accepted as an effective method to prevent infections by mounting pathogen-specific immune responses prior to the infection. Usually, immunization with vaccine antigens alone is not able to induce robust or long-lasting immune responses resulting in failure of protective immunity against infections. Thus, adjuvants are required to enhance cellular or humoral immune responses upon immunization. Vaccine adjuvants using biologically-derived Lipid A have proven to be safe and effective in inducing Th-1 type immune responses to heterologous proteins in animal and human vaccines. Experiments utilizing a new synthetic adjuvant, Phosphorylated HexaAcyl Disaccharide (PHAD ), demonstrated that the synthetic product had equivalent activity to the biologicallyderived Lipid A but with much lower toxicity. Phone 800-227-0651 (205-663-2494 International) or Email info@avantilipids.com for details of Avanti s selection of lipids of unparalleled purity visit www.avantilipids.com FROM RESEARCH TO CGMP PRODUCTION - AVANTI S HERE FOR YOU IMMUNOLOGY OF JOURNAL THE SPEND MORE TIME ON SCIENCE AND LESS TIME ONLINE You have better things to do than spend hours submitting and tracking manuscripts. The JI s new online manuscript submission and peer-review system is designed to make manuscript submission seamless for authors and peer review simple for reviewers. SUBMIT IN A SNAP! Try our easy 4-step submission process. Fast Efficient Easy to use JI Cover http://ji.msubmit.net

Viable Human Regulatory T Cell Analysis A new approach using CD127, CD25, and CD4 CD127-PE Pre Sort CD4 enriched PBMCs 9.6% CD25-FITC CD127-PE Post Sort CD25 int/ hi CD127 lo 85% CD25-FITC CD4-PerCP Post Sort CD25int/hi CD127lo CD4-PerCP vs FoxP3-APC 0.055 FoxP3-APC A revolutionary approach for identification, isolation, and characterization of viable Treg cells. You can now obtain viable Treg cells with a novel 3-color surface staining approach. No cellular permeabilization necessary Isolate viable cells for further experiments Increase recovery of CD25int/hi Treg cells Eliminate contaminating CD25-/int T-effector cells BD flow cytometers are class (I) laser products. For Research Use Only. Not for use in diagnostic or therapeutic procedures. Not for resale. BD, BD Logo and all other trademarks are the property of Becton, Dickinson and Company. 2007 BD. 06-810038-7r To learn more about Regulatory T Cells visit bdbiosciences.com/treg Shop online at shop.bdbiosciences.com BD Biosciences 2350 Qume Drive San Jose, CA 95131 bdbiosciences.com