PRESSURE FILTRATION

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1 Introduction Stainless Steel Syringe Holders Stainless Steel Gas Line Holders High Pressure Stainless Steel Holder Polypropylene In-Line Holders PFA In-Line Holders Sanitary In-Line Stainless Steel Holders Vented In-Line Stainless Steel Holder Large Standard Stainless Steel Holders Large Sanitary Stainless Steel Holders Large Stainless Steel Holders with Reservoirs Multi-Media Pressure Sealing Holders Pressure Vessels Stirred Cells

2 Introduction Pressure type filter holders can be used for ultracleaning or sterilizing liquids and gases. Advantec holders have been designed to maximize flow rates and to minimize holder resistance and can be used in either batch or continuous filtration procedures. Advantages of Pressure Filtration Higher differential pressures are possible, resulting in higher flow rates. The pressure differential across the membrane is not limited to atmospheric pressure (. psi) Unintentional contamination downstream of the membrane is minimized Denaturation of proteins and other biological polymers due to foaming downstream of the membrane is avoided Vapor accumulation and possible explosion can be avoided using an inert gas to pressurize solvents and combustible or flammable liquids R ECOMMENDED P RESSURE F ILTER H OLDERS FOR T YPICAL A PPLICATIONS AND V OLUMES Volume to be Filtered <0 ml <0 ml < liter < liters <0 liters >0 liters Typical Enzymes, Proteins, Biological media, Biological media, Biological media, Pharmaceuticals, Applications Radiolabelled enzymes, electrolyte ultrapure water, ultrapure water, cosmetics, large samples Radiolabelled solution for serum, gases serum, gases scale biologicals samples, gases counters, gases Recommended Models Luer Connection KS KS PP PP PFA Threaded - LS KS KS 0 KS KS Connection LS KS 0 UH KS UH KS UH LS HP PP PFA Sanitary - KS F KS F KS 0 ST KS ST KS ST Connection Holders with - - KST KST 0 KST - Reservoir Filter Specifications Membrane 0 Diameter (mm) Prefilter or,,., Diameter (mm) or Filtration 0...,., or.. 0 Area (cm ) Liquid Flow Rate (L/min) 0.0 µm µm µm µm Prefilter size varies with model refer to individual model specifications before choosing a prefilter.. Liquid flow rates represent typical initial water flow rates at 0. kg/cm (0 psi) differential pressure at 0 C using clean water filtered to 0. µm using MCE membrane. 00--

3 PRESSURE FI LTRATION Stainless Steel Syringe Holders Can be sterilized by standard procedures including autoclaving Luer fittings fit typical syringes Can be tightened securely, wrench set included A PPLICATIONS Filter or clean small volumes of liquid such as eyewash or photoresist Clear turbid solutions such as serum Purify virus solutions S PECIFICATIONS KS KS Body and support screen Type 0 Stainless Steel Gasket PTFE O-ring PTFE Connections: Female Luer-lock Outlet Male Luer slip Dead volume 0. ml 0. ml 0. MPa ( psi) Differential 0. MPa ( psi) Membrane Compatibility: Filter size mm mm Prefilter size mm mm Filtration area 0. cm. cm Dimensions: Diameter mm (0.") mm (.") Length mm (.") mm (.") Weight: 0. kg (0. lb) 0. kg (0. lb) O RDERING I NFORMATION Model KS KS Catalog No Replacement Parts KS KS, male O-ring (PTFE) Screen (0 SS) Gasket (PTFE) Outlet, female Universal wrenches (/pk) Stainless steel syringe holders KS

4 00 Stainless Steel Gas Line Holders Female threaded locking ring enables filter changes without removing the holder from connecting gas lines Dual support screens protect the membrane filter from reverse pressure surges and allow forward and reverse flow from either inlet or outlet Tighten by hand only, Hand torque maximum is. N.m ( lbs/in) A PPLICATIONS Ultraclean and sterilize air and other gases including compressed gases In-line between pressurizing source (pump or gas cylinder) and dispensing vessel Stainless Steel Gas Line Holders S PECIFICATIONS LS LS Body and support screen Type 0 Stainless Steel Locking ring Nickel-plated brass Gaskets PTFE O-ring (standard) PTFE Silicone Connections: /" NPTF, comes with hose barb fitting ( /") Outlet /" NPTM, comes with hose barb fitting ( /") 0. MPa ( psi) Differential 0.0 MPa ( psi) Filter Specifications: Filter size mm mm Prefilter size mm mm Filtration area. cm. cm Dimensions: Diameter mm (.") mm (.") Length 0 mm (.0") mm (.") Weight: 0. kg (0. lb) 0. kg (. lb) O RDERING I NFORMATION Model LS LS Catalog No Replacement Parts, Accessories, and Optional O-rings LS LS - Hose barb ( /" NPTM) 00 Locking ring Locking ring gasket (PTFE) body ( /" NPTF) Gasket (PTFE) a O-ring (Silicone) - 0 a O-ring (FPM) - 0 a O-ring (FEP encapsulated) - 0 Stainless steel screen (0 SS) Outlet body ( /" NPTM) Hose barb ( /" NPTF) 00 a LS LS 00--

5 PRESS U RE FI LTRATION 0 High Pressure Stainless Steel Holder Operate at high pressure, up to. MPa (0 psi) Standard FPM O-rings compatible with many aggressive liquids and gases Back pressure support screen available to prevent membrane rupture and deflect flow at very high pressures A P P L I C AT I O N S Filter liquids or gases under high pressure S P E C I F I C AT I O N S LS HP Body and support screen Type 0 Stainless Steel O-rings FPM Connections: and Outlet /" NPTF. MPa ( psi) Differential. MPa ( psi) Dead volume: Upstream ml Downstream. ml Membrane Compatibility: Membrane filter size mm Prefilter size mm Filtration area. cm Dimensions: Diameter mm (.") Height (including adapters) mm (.") Weight:. kg (. lb) LS HP O R D E R I N G I N F O R M AT I O N Model LS HP Catalog No. 000 Replacement Parts and Accessories LS HP /outlet adapter 00 Adapter O-ring 00 Hex cap screw, M- 0 Cap screw washer 0 plate 00 Inner O-ring 00 Outer O-ring 00 Sintered steel support 00 Outlet plate 00 - Back pressure support screen (optional) 00 LS HP w w w. a d v a n t e c m f s. c o m

6 0 Polypropylene In-Line and Aerosol Holders Compatible with a wide range of chemicals and temperatures Exterior locking ring design allows the unit to be assembled quickly and efficiently without tearing the membrane A PPLICATIONS Ultraclean and sterilize liquids Aseptic sampling of liquids or gases at point-of-use Environmental air sampling (PPO ) Polypropylene In-Line and Aerosol Holders S PECIFICATIONS PP PP PPO Body and support screen Polypropylene O-rings (standard) Silicone Silicone/PTFE Connections: Female Luer-Lock Combination /" NPTM, Open Face Female Luer slip Outlet Male Luer slip Combination /" NPTM, Combination /" NPTM, Female Luer slip Female Luer slip 0. MPa ( psi) - Differential 0. MPa ( psi) 0. MPa ( psi) - Temperature: Maximum operating (liquids) Autoclave 0 C ( F) C (0 F), psi, 0 min slow exhaust only Filter Specifications: Filter size mm mm Prefilter size mm. mm - Filtration area. cm. cm Recommended volume <0 ml Up to liter - Dimensions: Diameter 0 mm (.") mm (.") Height 0 mm (.") 0 mm (.0") Weight: 0. oz (g). oz (g) per pk/box O RDERING I NFORMATION Model PP PP PPO Catalog No

7 0 Typical initial liquid flow rates (in ml/min) Membrane Pore size (µm) PP PP Conditions: initial flow rates of water being filtered through a mixed cellulose esters (MCE) at a differential pressure of kg/cm ( psi) at 0 C. Replacement Parts and Optional O-rings PP Locking ring, outer 00 cap O-ring (silicone) 00 cap O-ring (FPM) 00 cap O-ring (EPR) 00 cap 00 Support screen 00 Outlet base 00 PP Locking ring, outer 00 cap O-ring (silicone) 00 cap O-ring (FPM) 00 cap O-ring (EPR) 00 cap 00 Support screen 000 Outlet base O-ring (silicone) 00 Outlet base O-ring (FPM) 00 Outlet base O-ring (EPR) 0 Outlet base 00 Outlet adapter (male luer slip 00 to hose barb) PP PP0 Locking ring, outer 000 cap O-ring (silicone) 00 a Sealing O-ring (PTFE) 00 Support screen 000 Outlet base 00 Outlet adapter (male luer slip 00 to hose barb) a PP PPO

8 0 PFA In-Line Filter Holders Superior chemical compatibility can be used with chemically aggressive liquids Dual support screens allow for flow in either direction Exterior locking ring for quick assembly without tearing the membrane A PPLICATIONS Sterilize and ultraclean liquids under positive pressure Ideal for filtering small volumes of high purity acids, alkalis or organic solvents Note: PFA unit has an air/bleed vent PFA, PFA S PECIFICATIONS Body and support screen O-ring (standard) Connectors: PFA PFA PFA Locking ring on PFA : ETFE glass fiber filled PFA Perfluoroelastomer Female Luer-Lock Combination /" NPTM, Outlet Male Luer slip /" tubing adapter Differential, positive or negative, at C Temperature: Maximum operating Autoclave 0. MPa ( psi) 0. MPa ( psi) C (0 F) C (0 F), min Weight: 0. oz (g). oz (0g) Dimensions: Diameter mm (.") mm (.") Height mm (.") 0 mm (.") Membrane Compatibility: Filter size mm mm Prefilter size mm. mm PFA PFA Filtration area. cm. cm Flow Rate: Pore size (PTFE membrane) Typical methanol flow rate at kg/cm, 0 C 0. µm (J00) 0 ml/min 00 ml/min 0. µm (J00) 0 ml/min 00 ml/min.0 µm (J00) 0 ml/min 00 ml/min Replacement Parts PFA PFA Locking ring /Outlet adapter - 0 Tubing adapter - 00 Vent cap - 00 cap Support screen O-ring Outlet O RDERING I NFORMATION Model PFA PFA Catalog No Optional O-rings PFA PFA O-ring (FPM) O-ring (EPR) O-ring (Silicone)

9 0 Sanitary In-Line Stainless Steel Holders Sanitary inlet and outlet connections are non-threaded and can be completely disassembled for thorough cleaning mm holder features vent to allow air venting on upstream side of the membrane at any time during filtration A PPLICATIONS Point of use filtration on sterile filling machines Flow decay studies for scale up to larger filtration systems Liquid or gas S PECIFICATIONS KS F KS F Body and support screen Type 0 Stainless Steel O-rings FPM and Silicone Gasket PTFE Connectors: /Outlet mm (0.") OD barb mm (0.") OD barb mm (0.") ID mm (0.") ID 0. MPa ( psi) Differential 0. MPa ( psi) Weight: 0. kg ( lb) 0. kg ( lb) Dimensions: Diameter (without clamp) 0 mm (.0") 0 mm (.") Length (with vent valve) mm (."). mm (.") Membrane Compatibility: Filter size mm mm Prefilter size mm mm ( mm)* Filtration area. cm. cm KS F, KS F * If a membrane filter is used as a prefilter, use a mm filter and place a polyester separator (DS type) between the membranes (See page 0). O RDERING I NFORMATION Model KS F KS F Catalog No Replacement Parts KS F KS F Vent valve with PTFE packing - 0 Vent valve O-ring (FPM) - 0 Valve body, female - 0 Vent valve gasket (PTFE) - 0 body 00 0 O-ring (silicone) 00 0 Support screen Gasket (PTFE) 00 - a Underdrain support - 0 Outlet body Clamp KS F 0 a KS F 0

10 0 Vented In-Line Stainless Steel Holder Support screen is PTFE coated to prevent membrane sticking during autoclaving Back pressure support screen prevents membrane rupture during reverse pressure surges Vent valve in inlet body enables venting at any time during filtration Available in type 0 or type stainless steel A PPLICATIONS Sterilize and ultraclean liquids or gases under positive pressure Sterilize with a membrane in place for microbiological studies Install for point of use filtration on filling machines KS Note: When using the KS inline to filter gases, a second support screen should be used upstream of the membrane S PECIFICATIONS Body and support screen O-rings (standard) Support screen Gasket Connections: Differential Dead Volume: Upstream Downstream Weight: Membrane Compatibility: KS Type 0 or stainless steel FPM and silicone PTFE coated stainless steel PTFE /" NPTM to hose barb (. mm) 0. MPa ( psi) 0. MPa ( psi) ml ml 0. kg (. lb) Filter size mm Prefilter size mm ( mm)* Filtration size. cm * If a membrane filter is used as a prefilter, use a mm filter and place a polyester separator (DS type) between the membranes (See page 0). 0 KS Replacement Parts KS Type 0 SS Type SS Vent valve with PTFE packing 0 Vent valve O-ring (FPM) 0 Valve body, female 0 Gasket (PTFE) 0 body 0 0 Back pressure support 0 0 O-ring (silicone) 0 Support screen 0 0 Underdrain support Outlet body 0 0 Locking ring 0 0 /outlet adapter O RDERING I NFORMATION KS 0 SS 00 SS 00 Accessories and Optional O-rings O-ring (PTFE encapsulated) 00 O-ring (FPM) 0 Support screen (order second 0 0 for upstream support, see note above) 00--

11 0 Large Standard Stainless Steel Holders 0,, mm Seal membrane by hand tightening locking wing nuts Optimal holder design minimizes resistance and maximizes flow rate Available in either type 0 or type stainless steel Each unit labeled with identifying serial numbers on the outside of both the inlet and outlet plates A PPLICATIONS Use in-line for filtering gases or liquids Use with pressure vessel (see page ) for batch type operations KS 0, KS, KS S PECIFICATIONS KS 0 KS KS Body Type 0 or stainless steel Support screen PTFE coated photoetched stainless steel O-rings (standard) Silicone Gasket PTFE Connections:, /" NPTF to: mm ( /") hose barb mm ( /") Outlet, /" NPTM to: hose barb 0. MPa ( psi) Differential 0. MPa ( psi) Weight: kg (. lb) kg ( lb) kg ( lb) Membrane Compatibility: Membrane filter size 0 mm mm mm Prefilter size mm mm mm Filtration area cm cm 0 cm Supplied with aluminum wrench (spanner) and mm allen wrench (hex key). O RDERING I NFORMATION KS 0 KS KS 0 SS SS

12 0 Replacement Parts and Outlet Assemblies KS 0 KS KS adapter (0 SS) 00 0 adapter ( SS) 00 0 Vent relief valve 0 plate (0 SS) plate ( SS) Outlet plate (0 SS) Outlet plate ( SS) Outlet adapter (0 SS) Outlet adapter ( SS) 00 0 Filter Support System KS 0 KS KS Flow deflector ( SS) 00 O-ring (silicone) Support screen (PTFE coated SS) Gasket (PTFE) Underdrain support ( SS) Sealing and Support Assemblies KS 0 KS KS Leg Leg washer 00 0 Leg bolt 0 - Sealing wing nut 0 0 Sealing washer 0 0 Sealing bolt 0 0 Accessories and Optional O-rings KS 0 KS KS O-ring (FEP-encapsulated silicone) O-ring (FPM) Support Screen ( SS) Back pressure support screen (0 SS) Back pressure support screen ( SS) Back pressure support screen (PTFE coated 0 SS) Back pressure support screen (PTFE coated SS) Allen wrench (hex key) mm Spanner (wrench) mm 0 0 KS 0, KS 0 KS 00--

13 0 Large Sanitary Stainless Steel Holders 0,, mm Sanitary connections are threadless and can be completely disassembled for thorough cleaning Designed for minimal resistance and maximal flow Available in either type 0 or stainless steel Removable wing nuts tighten easily by hand to seal membrane Both inlet and outlet plates clearly marked with identifying serial number A PPLICATIONS Ultraclean or sterilize gases or liquids Use with a pressure vessel for large volumes and batch type operations S PECIFICATIONS Body Type 0 or stainless steel Support screen PTFE coated photoetched stainless steel O-ring (standard) Silicone Gaskets (standard) PTFE and Silicone Connections: and Outlet /" sanitary fitting to. mm hose barb 0. MPa ( psi) Differential 0. MPa ( psi) Supplied with aluminum wrench (spanner) and mm allen wrench (hex key). KS ST O RDERING I NFORMATION KS 0 ST KS ST KS ST 0 SS SS Assemblies are available with PTFE coating by special order.

14 0 Replacement Parts and Outlet Assemblies KS 0 ST KS ST KS ST /Outlet adapter (0 SS) 00 /Outlet adapter ( SS) 00 /Outlet gasket (silicone) 00 Clamp,. Tri-Clamp 0000 Vent relief valve 0 plate (0 SS) plate ( SS) Outlet plate (0 SS) Outlet plate ( SS) Filter Support System KS 0 ST KS ST KS ST Flow deflector ( SS) O-ring (silicone) Support screen (PTFE coated SS) Gasket (PTFE) Underdrain support ( SS) Sealing and Support Assemblies KS 0 ST KS ST KS ST Leg 0 0 Leg bolt 0 - Leg washer 00 0 Sealing wing nut 0 0 Sealing washer 0 0 Sealing bolt 0 0 Handle KS 0 ST KS ST Accessories and Optional O-rings KS 0 ST KS ST KS ST O-ring (FEP-encapsulated silicone) O-ring (FPM) Support Screen ( SS) Back pressure support screen (0 SS) Back pressure support screen ( SS) Back pressure support screen (PTFE coated 0 SS) Back pressure support screen (PTFE coated SS) /Outlet gasket (PTFE) 00 /Outlet gasket (FPM) 00 - Allen wrench (hex key), mm Spanner (wrench), mm 0 0 KS ST 00--

15 Large Stainless Steel Holders with Reservoirs Designed for filtering small batches of liquid without having to use a separate pressure vessel Separate ports for pressurizing the reservoir and for adding additional sample Membrane sealed internally by hand-tightening locking wing nuts Available in either type 0 or stainless steel A PPLICATIONS Sterilizing, ultracleaning, and flow decay tests for pilot studies Suitable for hazardous toxicity testing and TCLP Optional back pressure screen recommended for intermittent fill operations KST KST 0 S PECIFICATIONS KST KST 0 KST Body Type 0 SS Type 0 or SS Support screen Photoetched 0 SS PTFE coated photoetched 0 SS O-rings (standard) Silicone Gasket (standard) Silicone/PTFE PTFE Connections: /" NPTM adapter mm hose barb Ball valve with stepped hose barb ( mm, 0. mm, mm) Outlet /" NPTM /" NPTM Outlet adapter 0 mm hose barb mm hose barb 0. MPa ( psi) Differential 0. MPa ( psi) Vent relief valve 0. ± 0.0 MPa ( ± psi) Weight: kg (. lb) kg ( lb) kg ( lb) Capacity: 00 ml 0 ml. L Membrane Compatibility: Membrane filter size mm 0 mm mm Prefilter size mm mm mm Filtration area. cm. cm cm Supplied with aluminum wrench (spanner) and mm allen wrench (hex key).

16 O RDERING I NFORMATION KST KST 0 KST 0 SS SS Assemblies are available with PTFE coating by special order. Replacement Parts Assembly KST KST 0 KST cap cap gasket/o-ring (silicone) Clamp,. TC Vent relief valve 0 Vent socket - 0 adapter (0 SS) 0 adapter ( SS) - Valve (0 SS) - Valve ( SS) - Holder Body and Filter Support System KST KST 0 KST Reservoir (0 SS) Reservoir ( SS) O-ring (silicone) Support screen (0 SS) a Support screen (PTFE coated SS) Gasket (PTFE) Underdrain support ( SS) Outlet plate (0 SS) Outlet plate ( SS) Sealing and Support Assemblies KST KST 0 KST Guide pins Sealing bolt (leg) - 0 Locking washer (leg) - 00 Leg Wing-type bolt 0 0 Sealing washer Wing-type nut 0 0 Outlet adapter (NPTF to hose barb) Accessories and Optional O-rings/Gaskets KST KST 0 KST cap O-ring (FEP-encapsulated silicone) cap gasket (FPM) 00 - cap gasket (PTFE) 00 - O-ring (FEP-encapsulated silicone) O-ring (PTFE) 00 - O-ring (FPM) Back pressure support screen (0 SS) Back pressure support screen ( SS) Back pressure support screen (PTFE coated 0 SS) Back pressure support screen (PTFE coated SS) Allen wrench (hex key) mm Spanner (wrench) mm - 0 0a 0 KST KST 0 KST

17 Multi-Media Pressure Sealing Holders Dual sealing system compresses the filter between the inside wall of the outlet plate and the O-ring on the outer edge Broad range of media thickness, including pads, can be used without compromising sealing up to mm Multiple layers of media can be used in a single holder without lateral wicking S PECIFICATIONS KS 0 UH KS UH KS UH Body Type 0 stainless steel Support screen PTFE coated photoetched stainless steel O-ring Silicone Connections: /Outlet /" NPTF/ /" NPTM Adapter mm hose barb mm hose barb 0. MPa ( psi) Differential 0. MPa ( psi) Weight:. kg (. lb) kg (. lb) kg ( lb) Membrane Compatibility: Membrane filter size 0 mm mm mm Prefilter size mm mm mm Filtration area. cm cm 0 cm KS UH O RDERING I NFORMATION Model KS 0 UH KS UH KS UH Catalog No

18 Replacement Parts Assembly KS 0 UH KS UH KS UH adapter 00 0 Vent relief valve 0 plate Holder Body and Filter Support System KS 0 UH KS UH KS UH Flow deflector 00 O-ring (silicone) Support screen (PTFE coated SS) Underdrain support ( SS) Outlet plate Sealing and Support Assemblies KS 0 UH KS UH KS UH Leg bolt 0-0 Locking washer (leg) 00 - Leg Sealing wing nut Sealing washer Sealing wing bolt Outlet adapter 00 0 IN OUT Sealing mechanism 0 KS 0 UH 00--

19 Pressure Vessels Stainless Steel Type 0 or L gallon to 0 gallon sizes (. to liters) Standard or Wide Mouth openings available for ease of cleaning ASME certified: a certificate of analysis is available upon request S PECIFICATIONS Vessel Skirt: gallon Skirt: 0 gallon Type 0 or type L stainless steel Molded neoprene rubber Stainless steel Connections: /outlet /" NPTF Standard closure /" x /" Wide mouth closure /" x /" Max. operating Optional relief valve Max. negative Temperature: Max. operating See table below 0. MPa (00 psi) kpa (" Hg) See table below Electropolished finish provides a smooth, releasable, cleanable surface Disassemble completely for thorough cleaning Molded rubber base protects the vessel against rough handling (available with steel base for continuous operation at high temperatures) Use under positive or negative pressure Optional vacuum closure available when working with negative pressure or when operating at low pressures (<0 psi/. bar) or with stiffer O-rings (FPM) Special orders available (coatings, additional sizes) A PPLICATIONS Contain process fluids for filtration through pressure type membrane filter holders Type /L stainless complies with current good manufacturing practices and are recommended for low ph and high salt applications Volume: U.S. gallons gal gal gal gal 0 gal Liters. L. L. L 0. L. L Dimensions: Overall height. cm. cm. cm. cm. cm."."." 0."." Inside diameter. cm (") 0. cm (") Weight:. kg kg. kg. kg. kg lb lb lb. lb. lb Recommended for use with: Pressure Filter KS 0 KS KS Holders KS 0 ST KS ST KS ST KS 0 UH KS UH KS UH M AXIMUM O PERATING T EMPERATURE AND P RESSURE Type of Maximum Operating,, gallon models and 0 gallon models Stainless Steel Temperature Standard Opening Wide Mouth Standard Opening Wide Mouth F C psi MPa psi MPa psi MPa psi MPa Type Type L Note: O-rings containing silicone rubber should not be operated extensively at temperatures over 0 F ( C).

20 Pressure Vessels With an opening / times larger, the Wide Mouth vessel is easy to clean and inspect. O RDERING I NFORMATION Complete Assemblies Standard opening Wide Mouth opening Type Stainless Steel (SS) 0 SS L SS 0 SS L SS Capacity: gallon gallon gallon gallon gallon Pressure vessels are available in other sizes by special order. Replacement Parts L SS Dip tube assembly: gallon 0 gallon 0 gallon 0 gallon 0 0 gallon 0 Closure: Standard 0 Wide mouth 0 Plastic feet for closure assembly: 00 Optional Parts and O-rings Standard opening Wide Mouth opening Standard closure ( SS) 0 0 Vacuum closure ( SS) 0 0 O-ring (EPR) O-ring (FPM) O-ring (PTFE encapsulated silicone rubber) EPR (ethylene propylene rubber) O-rings are manufactured from E00-0 EPDM and meet FDA CFR, 00 and ASTM D000 specifications. Accessories /" NPT Type of stainless Catalog No. Vent/relief valve: kg/cm, 00 psi Male 0 SS 0 Pressure gauge : 0 0 psi Male Hose barb ( mm) Male 0 SS 00 Hose barb ( mm) Female 0 SS 00 Pipe plug Male 0 SS 0 Elbow fitting Male/Female SS 000 Ball valve Male/Female SS 000 Close nipple Male/Male SS 000 Quick-connect body Male SS 000 Quick-connect stem (hose barb) - SS 000. All parts are available in (hose barb) type stainless steel by special order.. Caution: pressure gauges should not be autoclaved.. All wetted parts consist of a copper alloy, and the threaded connector is made of brass. 00--

21 PRESS U RE FI LTRATION Stirred Cells Tangential flow design increases membrane life and sample throughput PTFE stir bar is mounted to stay clear of the membrane All contact surfaces are non-metal Clear plastic reservoir allows for fluid level and sample condition to be visually monitored Removable top cap (UHP,, and ) and sample port (UHP, 0, 0) allow sample to be added during filtration Pressure relief valve supplied A P P L I C AT I O N S Desalting and concentrating proteins, enzymes, virus, and other biological samples Filtering fluids that contain a heavy particle burden, e.g. bacteria, silts Note: Cells are not autoclavable Stirred Cells S P E C I F I C AT I O N S End caps and stir rod UHP UHP UHP UHP UHP 0 UHP 0 Polyacetal Cell barrel Polycarbonate Acrylic O-rings Support screen Stir bar Connections: Pressurizing Vent valve Maximum Vent relief valve Silicone Polypropylene PTFE M0 0 mm screw, female 0. MPa ( psi) 0. ± 0.0 MPa ( ± psi) Max. Operating 0 C Temperature Dimensions: Diameter 0 mm mm mm mm mm mm Height mm mm 0 mm mm 0 mm. mm Weight: 0.0 kg 0. kg 0. kg 0. kg. kg. kg Volumes: 0. lb 0.0 lb 0. lb.0 lb.0 lb. lb Capacity 0 ml 0 ml 00 ml 0 ml 00 ml 000 ml Min. recoverable 0. ml. ml. ml 0 ml ml 0 ml upstream Downstream. ml. ml. ml ml 0 ml ml holdup Membrane Compatibility: Membrane mm mm mm mm 0 mm 0 mm filter size Filtration area. cm. cm.0 cm. cm. cm cm UHP, 0, 0 O R D E R I N G I N F O R M AT I O N Model UHP UHP UHP UHP UHP 0 UHP 0 Catalog No w w w. a d v a n t e c m f s. c o m

22 Replacement Parts Assembly All Models Pressurizing hose 00 Hose clamp 00 Male hose adapter 00 Hose adapter assembly 0 nipple adapter adapter O-ring (silicone) 0 Vent/relief valve (with washer) 0 Vent valve O-ring (silicone) 00 Port Assembly (UHP, 0, 0) UHP UHP 0 UHP 0 End cap adapter 00 0 port adapter cap O-ring Sample port inlet cap Sample port adapter O-ring Sample port tube Body 0 UHP,, UHP UHP UHP UHP UHP 0 UHP 0 end cap 0 Stir rod 0 Stir bar and adapter 0 Set bolt for stir bar cap O-ring (silicone) Outlet cap O-ring (silicone) 0 0 Cell barrel 0 Support screen (polypropylene) 0 Outlet end cap Locking ring Outlet Assembly UHP,, UHP UHP 0 UHP 0 Outlet tubing 0 Outlet adapter 0 Outlet adapter O-ring 0 Clamp Assembly (UHP, 0, 0) UHP UHP 0 UHP 0 Nut for tie rod Washer for tie rod 0 0 Tie rod 0 0 Set pins Cell on Stirrer

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