SCIENTIFIC CURRICULUM March 2012

Transcription

1 SCIENTIFIC CURRICULUM March 2012 Research Areas Research Coordinators: Dr. Eng. Laurent Aubouy: Meritxell De la Varga: YOUR TECHNOLOGICAL PARTNER LEITAT Technological Center Phone Fax

2 LEITAT Technological Center VOCATION We offer high added value solutions to technological challenges required by companies, with a clear guidance and vocational adaptation to the constant market changes. FUTURE VISION We support sustainable growth through the promotion of R+D+I and technology transfer, in the context of creating lasting value for companies, satisfying the changing demands of global market. RESEARCH UNITS From a traditional structure to a flexible and dynamic organization, LEITAT seeks to ensure a rapid and effective response by reducing levels of decision-making and bureaucracy. Prioritizing teams work and projects with a horizontal communication and a definition of responsibilities in order to achieve meet the expectations of the client and society. 2

3 INDEX Page INDUSTRIAL BIOTECHNOLOGY 4 BIOINVITRO 7 BIOMED 10 NANOHEALTH & SAFETY 13 ANALYTICAL CHEMISTRY 16 FAST MOVING CONSUMER GOODS 19 NANOMATERIALS 22 ADVANCED POLYMERS 25 SURFACE TREATMENTS 28 TEXTILE TECHNOLOGIES 31 SMART SYSTEMS 34 NEW PRODUCTION PROCESSES 37 ENVIRONMENT 40 RENEWABLE ENERGIES 43 LEITAT TECHNOLOGICAL CENTER IS MEMBER OF 46 EUROPEAN TECHNOLOGY PLATFORMS 46 SPANISH TECHNOLOGY PLATFORMS 47 3

4 INDUSTRIAL BIOTECHNOLOGY Competency Compendium Dr. Anna SURRIBAS Coordinator of Industrial Biotechnology Division Equipments: Bioreactors Incubators Equipment for protein/enzyme activity characterization (SDS-PAGE) Microbiology laboratory Microscopy facilities Dispermat CV3 Spray drier Rulla Quirsec Pilot scale fat crystallizer Pilot scale homogenizer SPECIFIC RESEARCH INTERESTS Bioprocess development: - Design and application of bioprocesses in industrial environment: use of enzymes and microorganisms: Several activities can be addressed from biocatalyst screening, modification and bioprocess development. Several analytical technologies can be set up for process monitoring. - Enzyme immobilization, recuperation and reutilization. Kinetic studies: Immobilization systems can be selected from commercial sources or specially designed and synthesized for custom needs by micro and nanotechnologies. Enzyme activity protocols can be set up to follow enzyme activity during immobilization. Several separation technologies can be studied ranging from filtration, magnetic separation, centrifugation - Substitution of organic conventional reactions by biocatalytic reactions: Given a chemical process, several alternatives can be designed in order to include biotechnological routes for the synthesis of certain intermediates or products. Activities can include the process strategy, biocatalyst selection and process development. Product analysis and separation can be also addressed. - Isolation, selection and characterization of microorganisms for different applications and functionalities: Novel microorganism can be isolated by strategic sampling according to the desired applications, for example contaminated soils for contaminant-degrading microorganisms. Screening methods can be designed to select the best strains. Environmental Biotechnology. - Biotechnological wastewater treatment: Both enzymatic and microbial processes for the environmental sector can be developed. Activities include the development of enzymatic processes for wastewater treatment, isolation of new microbial consortia, anaerobic digestionetc.. 4

5 - By-product/waste valorisation: Biotechnological processes can be designed for the valorisation of certain by products. Activities have been addressed for the recovery of by product fibres, protein hydrolysates, feed, biopolymers. - Microbial/Enzymatic fuel cells technology: MFC can be designed with preferred microorganisms or novel electrode materials for electricity recovery. Applied microbiology: - Application of antimicrobial/antimite ingredients and validation of their activity: Antimicrobial products can be applied on different substrates (textiles, polymeric materials, membranes) and surfaces and their antimicrobial behaviour can be assessed through international standards. - Tailor made microbiological research: Tailor made microbiological research activities can be designed to fulfil customer needs: study of biofilm formation, validation of higienization technologies, evaluation of antimicrobial compounds and antimicrobial behaviour of products (detergents, cosmetics, food conservants ) Microencapsulation for several industrial sectors: textiles, food, cosmetics, etc. Development of tailor-made microcapsules for applications in several industrial sectors. Activities include: microcapsules development (using chemical technologies: Coacervation, gelation, interfacial polymerization, sol-gel; spray-drying;); microcapsule characterization and release and stability studies. Identification of valuable compounds from natural origin Screening methodologies for identifying novel added-value compounds from natural resources into biologically valuable compounds. Development of improved fat based products Downstream processing. Several technologies and processes can be developed and applied for downstream applications: membrane and tubular filtration, filter press, centrifugation Filtration technologies are available at a pilot scale. Purification methodologies can be developed according to custom needs. Equipment for protein purification by FPLC is available. MOST RELEVANT PROJECTS 1. ITACA: Research on Technologies of treatment, reuse and monitoring for future sustainability of water treatment. INNPRONTA 2011, IPT BioConSepT: Integration of Bio-Conversion and Separation Technology for the production and application of platform chemicals from 2nd generation biomass. FP7-KBBE BioXplore: Novel methodology for the identification of valuable natural products derived from Mediterranean Flora. ENPI 4. MICROSEGA: Biopolymeric microcapsules for food safety applications. VALOR LIQUION: Research on ionic liquid technologies for industrial applications. Co-financed by CDTI. CEN PHILYRA: Microbiological characterization on textiles. Henkel KGaA Research in Healthy Foods and Products.(INVIAS). CDTI project with Grup Lasem. IDI SEILA: New Technologies for an efficient, ecologic and intelligent washing system for the future textiles, CENIT CEN INSEPLATEX: Development of plastics and textiles with insect repellent and insecticide effect. LIA I+D+i CONSORCIADO, 2009 PID

6 10. FIBNATEX: Production and technical evaluation of natural fibres for the European south-western industry. INTERREG SUDOE IV B, SOE1/P1/P SAFEPROTEX: High protective clothing for complex emergency operations. FP7-NMP-2008-SME-2 project number Fellowship on Enzyme Immobilization. Talent Empresa, 2009 TEM Investigation of alternative technologies for industrial wastewater treatment. Ministry of Industry, Tourism and Trade. 15/5/ /12/09. DEX Technological transfer of new methodologies of enzymatic cotton processing in substitution of conventional methods. PET2008_ Immobilized enzymes for their use and re-use in textile processes. 2008ACOM Surface treatments to obtain antimicrobial materials IAP Modification of polyester surface using plasma and enzymatic technologies, IAP Design of bio-reactions with biocatalysts (enzymes) with application in industrial processes of the textile sector, Icrea Junior Empresa PUBLICATIONS AND ORAL COMMUNICATONS 1. A. Mª. Lozano, M. Arnautu, L. Bautista, M. de la Varga. "Textile with antimicrobial properties obtained by polymerization of bifunctional quaternary ammonium derivatives. 21st IFATCC Congress 2008, Conference, Full text paper in the Congress Proceedings, Barcelona (Spain), 7-9 May M. de la Varga. Industrial Biotechnology in textile sector, INDUSTRIAL BIOTEC 2008, Oral Communication, Brusseles (Bèlgica), June M. Garrido-Franco, Combination of enzymatic methods for the (semi)continous processing of cotton", BIOTEC 2008, Oral Communication, Granada, September M. de la Varga, M. Garrido-Franco, Biotechnological solutions for conventional cotton treatments, EXPOQUIMIA 2008, Conference, Barcelona, October R.Paul, A.Surribas, M. Brouta, M. Alaman and H. Esteve Hemp: an ecologic textile alternative. Revista Química Textil, 195: Anna Surribas, Marta Alamán, Alexandre Martínez, Marta Garrido, J. M. Botet Meritxell De la Varga. Methodologies for cotton pretreatment by enzymatic processes in substitution to conventional treatments. Revista de Química e Industria Textil, 198: A.Surribas. White Biotechnology. Learning session at the Universitat Autònoma de Barcelona. Bellaterra (Spain), 3 rd October Anna Ribé, Marolda Brouta-Agnésa, Elena Genescà, Roshan Paul. PALF: Nuevas oportunidades para la fibra de hoja de piña. Revista de Química e Industria Textil, 204: Laia Crespo, Ana Serret, Llorenç Bautista, Helena Esteve, Meritxell de la Varga, Anna Surribas, Roshan Paul. Chitosan Microspheres for Antibacterial Finishes. Full text paper in the world textile conference (Autex 2011) 10. Anna Surribas, Elena Genescà, Aleix Conesa, Roshan Paul, Marolda Brouta-Agnésa and Meritxell de la Varga. Novel industrial applications of enzymatic conversions. 9th Green Chemical Congress. Alcalà de Henares. 15th September E.Genescà White biotechnology: applications and status of the industry OCTUBREBIO 2011, Technological Center of La Rioja, Logroño (Spain), 4th October I. Forns, M. Brouta, T. Copete. Antimicrobial Fabrics Workshop at Innovation Afternoons CICLE 2011, LEITAT, Terrassa (Spain), 15th December

7 BIOINVITRO Competency Compendium Dr. María-Jesús ZURBANO Coordinator of the BioInVitro Division Main research fields: In vitro technologies, customized research for cosmetic development and claim support, in vitro ADMETOX assays, development of ready-to-use cell-based kits for in vitro ADMETOX studies. Equipments: Laminar flow hoods CO2 incubators Equipment for cell isolation Leica DM IRBE microscope, equipped with fluorescence module and Leica ACC88 digital camera Leica DMI 4000B Microscope equipped with fluorescence modules and Leica DFC 300FX digital camera Scan^R, Olympus Multiskan Ascent microplate spectrophotometer Elisa reader, SLT Lab Instruments 340 ATTC Fluoroskan Ascent FL fluorimeter Fluorimeter, Molecular Devices Spectra MAX Gemini XS Refrigerated centrifuges Lightcycler PCR 1.5, Roche Safire 2 microplate absorbance fluorescence and luminiscence reader Vertical freezer -80 ºC Spectrophotometer Shimadzu model UV-240 High Performance Liquid Chromatography Triple Quadrupole Mass spectrometry: Waters Quattro Micro Ultra Performance Liquid Chromatography Triple Quadrupole Mass spectrometry: Waters Acquity - Xevo TQ-S Ultra Performance Liquid Chromatography Q-TOF Mass spectrometry: Waters Acquity - Synapt QTOF High Performance Liquid Chromatography Q-TOF Mass spectrometry: Agilent 1100 ABSciex QSTAR Elite High Performance Liquid Chromatography UV / FLD: Waters 2795 Full access to the Science Park of Barcelona (PCB) scientific and technical platforms, and to the University of Barcelona (UB) scientific and technical services, comprising: 1) PCB: Automated Crystallography Platform, Animal Research Centre, Combinatorial Chemistry Unit, Drug Discovery Platform, Nanotechnology Platform, Polymorphism and Calorimetry Platform, Proteomics Platform, Transcriptomics Platform, Unit of Experimental Toxicology and Ecotoxicology, 2) UB: Quality Assurance Unit, Genomics Unit, Magnetic nuclear resonance Unit, Transcriptomics Unit, Proteomics Unit, Fine chemistry Unit, Peptide synthesis Unit, Nanometric Techniques Unit, Cytometry Unit, Confocal microscopy and cellular micromanipulation Unit, Electron microscopy and in situ molecular identification Unit, Separative tecnhiques Unit. 7

8 SPECIFIC RESEARCH INTERESTS Skin biology/care. The expertise of BioInVitro Division members rely on more than 10 years of experience in cell culture, molecular biology, toxicity and efficacy studies. Assays and models can cover both safety and efficacy testing of raw materials or final products. We can also provide customized research and scientific consulting to cosmetic industry. Our in vitro systems are of special value to support marketing claims to provide insights into cell molecular mechanisms. These systems are useful at early stages of product development, as an alternative to animals, and prior to in vivo assessment in human volunteers. Some of our assays include anti-aging, vitalizing, firmness, anti-oxidant effect, elasticity, anti-inflammatory effect, moisturizing, skin repair, photoprotection, reconstruction, calming effect, use of reconstructed 3D human tissues, irritation and corrosion testing, acute toxicity, citotoxicity, phototoxicity, genotoxicity, teratogenicity and skin sensitization. Studies are conducted following Good Laboratory Practices, as well as, OECD and ECVAM test procedures. ADME and toxicity. Our team can help you in your in vitro Absorption, Distribution, Metabolism and Toxicity assays following rigorous quality standards under FDA guidelines and GLP standards. We conduct in vitro models based on cells. In vitro approaches are often extremely cost-effective in comparison with in vivo studies. In vitro studies allow a lot of information to be generated within a short time and at an acceptable cost during early stages of development, as well as evaluation of new molecules and active ingredients. We provide our customer problem solving in drug metabolism to support their drug discovery and development processes using, different in vitro systems, including microsomes, systems expressing individual CYPs (recombinant microsomes and engineered cell lines) and freshly isolated hepatocytes from different species. Additionally, we offer bio-analytical support through method development and validation, in vitro bioequivalence, metabonomics and proteomics. Absorption: Intestinal barrier, skin barrier, renal barrier, blood brain barrier, transport studies (FDA Guidance and EMEA Guidelines), drug delivery and Biopharmaceutical Classification System. Distribution: Partition coefficient and Protein Binding (plasma/serum). Metabolism: Drug metabolism stability, drug clearance, drug-drug interaction (drug inhibition and induction studies on CYP450 and UGT enzymes), phenotyping of Phase I enzymes (CYP P450 enzyme mapping), quantification of Phase II metabolizing enzymes (UGT1A1, UGT1A6, UGT1A9 and UGT2B7), protein binding, adduct formation, interspecies metabolic comparison, metabolite identification and structural Q- TOF analysis, multivariate analysis for biomarker selection (PLSDA, PCA), pattern recognition in metabolomic studies (PLSDA, PCA), skin metabolism. Toxicity: Classical cell-viability assays (MTT, WST-1, NRU, LDH), acute toxicity, genotoxicity, phototoxicity, photogenotoxicity, mitochondrial toxicity (ATP balance, mitochondrial membrane potential, oxidative stress), metabolic alterations (albumin synthesis, ureogenesis, carbohydrate metabolism, intracellular calcium levels) and hepatotoxicity (general hepatotoxicity, esteatosis, toxicity mechanism identification, multiparametric assay) MOST RELEVANT PROJECTS 1. NANOTEST: Alternative Testing Strategies for the Assesment of the toxicological profile of nanoparticles used in medical diagnosis. FP7. HEALTH CARCINOGENOMICS: Development of in vitro test methods for identification of carcinogenic substances. FP6. LIFESCIHEALTH LSH ACUTETOX: Developing an in vitro test strategy sufficiently robust and powerful to completely replace in vivo testing of acute toxicity of chemicals. FP6. LIFESCIHEALTH LSH

9 4. LINTOP: Optimization of liver and intestine in vitro models for pharmacokinetic and pharmacodynamic studies. FP6. LIFESCIHEALTH LSH PUBLICATIONS 1. Quintás G et al. Chemometric approaches to improve PLSDA model outcome for predicting human nonalcoholic fatty liver disease using UPLC-MS as metabolic profiling tool. Metabolomics 2011 (in press). 2. Kuligowski J et al. Direct determination of polymerized triacylglycerides in deep-frying vegetable oil by near infrared spectroscopy using Partial Least Squares regression. Food Chemistry 2011 (in press). 3. Schroeder K et al.. Report from the EPAA workshop: In vitro ADME in safety testing used by EPAA industry sectors. Toxicol In Vitro. 25: , Vila MR et al. A new ready-to-use concept for in vitro evaluation of biotransformation-mediated toxicity (Abstract). Toxicology Letters, 2010, 196S, S37-S Gombau L et al. Assessment of the inhibition on major human CYP450 isoforms as a predictor of putative interaction on concomitantly administered drugs for a new compound under development. An activity of the Melius project (Abstract). Toxicology Letters 2010, 196S, S37-S Quintás G et al. Metabolic characterization of PB60 and PB65, two peptidomimetics which notably facilitate the transport of heparin across the intestinal barrier. An activity of the Melius project (Abstract). Toxicology Letters 2010, 196S, S37-S Gómez-Lechón MJ et al. In vitro evaluation of potential hepatotoxicity induced by drugs. Curr Pharm Des. 2010;16(17): Kuligowski J et al. Sample classification for improved performance of PLS models applied to the quality control of deep-frying oils of different botanic origins analyzed using ATR-FTIR spectroscopy. Anal Bioanal Chem Jan;399(3): Dusinska M et al. Testing strategies for the safety of nanoparticles used in medical application. Nanomedicine Aug; 4(6): Quintás G et al. Use of Fourier transform infrared spectrometry for the on-line study of focusing mechanism in capillary electrophoresis. Analytical and Bioanalytical Chemistry 2007, 387, Lahoz A et al. In Vitro ADME Medium/High-Throughput screening in drug preclinical development. Mini- Reviews in Medicinal Chemisry 6: , Gombau L et al. Polypodium leucotomos extract: antioxidant activity and disposition. Toxicol In Vitro 20:464-71, Lahoz A and Gombau L Alteraciones en la función celular por la acción de fármacos. Las ómicas: Genómica, Proteómica, Citómica y Metabolómica. Nuevas tecnologías para el desarrollo de fármacos. Chap 9. Detección de las alteraciones de la función celular en el desarrollo de nuevos fármacos. Pag , Serradell M et al. Uremic medium causes expression, redistribution and shedding of adhesion molecules in cultured endothelial cells. Haematologica Oct;87: Serradell M et al. Uremic media affects hemostatic properties of human endothelial cells in cultureand increases the production of von Willebrand factor. Nefrologia. 2002;22: Sitges M et al. Acute and mid-term combined hormone replacement therapy improves endothelial function in post-menopausal women with angina and angiographically normal coronary arteries. Eur Heart J Nov;22 (22): Gálvez A et al. Desmopressin (DDAVP) enhances platelet adhesion to the extracellular matrix ofcultured human endothelial cells through increased expression of tissue factor. Thromb Haemost May; 77 (5):

10 BIOMED Competency Compendium Dr. Francesc MITJANS Coordinator of the Biomed Division Main research fields: Cancer therapy; diagnosis, prognosis & monitoring of diseases; specialized bioservices including monoclonal antibody generation and functional activity profiling of potential drugs, compounds and extracts. Equipments: Laminar flow hoods, CO2 incubators, Roller cell culture system, Leica DMIL microscopes, one equipped with fluorescence modules and Leica DF420C digital camera, Multiskan Ascent microplate spectrophotometer, Leica RM2255 fully motorized rotary microtome & Histobath, Fluoroskan Ascent FL fluorimeter, Refrigerated centrifuges, PCR Stratagene equipment, Robotized liquid handling workstation modules, AutoMACSpro, AKTA purifier system Full access to the Science Park of Barcelona (PCB) scientific and technical platforms, and to the University of Barcelona (UB) scientific and technical services, comprising: PCB: Automated Crystallography Platform, Animal Research Centre, Combinatorial Chemistry Unit, Drug Discovery Platform, Nanotechnology Platform, Polymorphism and Calorimetry Platform, Proteomics Platform, Transcriptomics Platform, Unit of Experimental Toxicology and Ecotoxicology. UB: Quality Assurance Unit, Genomics Unit, Magnetic nuclear resonance Unit, Transcriptomics Unit, Proteomics Unit, Fine chemistry Unit, Peptide synthesis Unit, Nanometric Techniques Unit, Cytometry Unit, Confocal microscopy and cellular micromanipulation Unit, Electron microscopy and in situ molecular identification Unit, Separative tecnhiques Unit. SPECIFIC RESEARCH INTERESTS Oncology / Therapy The expertise of Biomed Division members rely on more than 15 years of experience in basic and applied oncologic research in the pharmaceutical industry arena. Some of the targets and drug candidates previously developed by our scientists are currently in phase III, II, and I oncologic clinical trials. Actually, our therapeutic focus is cancer in its broad sense and therefore represented by any of the three compartments: tumour (tumoural cells), vascular (activated endothelial cells), stromal (support cells), and also including cancer stem cells and metastatic dissemination. Recent R&D activities also include inflammation and autoimmune diseases The principal investigation activity of the team involves the identification of new oncology therapeutic targets, the validation of these targets, the generation of therapeutic agents (specially monoclonal antibodies, Mabs), the study of its mechanisms of action, and the functional characterization of these agents (monoclonals and chemical compounds) in validated in vitro & in vivo models of both tumor progression and tumor angiogenesis. Final aim is to deliver these innovative drugs as clinical development candidates (preclinical proof of principle - PoP). Diagnosis An additional goal includes the design and characterization of front-edge reagents, tools and devices (biosensors) for diagnosis, prognosis and monitoring of cancer and other diseases. 10

11 Biomed Division goal is to position itself as a reference center in theragnosis. Specialized bio-services We provide consultancy and assessment services in drug discovery programs. Based on our oncologic profiling resources we are able to provide the basis to identify unrevealed indications for known leads. We perform reprofiling/repositioning research for oncologic, inflammatory and autoimmune disorders. Additional R&D tailored research for customers and collaborations include the next technological platforms: In vitro cell models (oncology, immunology, inflammation: proliferation, viability, apoptosis, nanotox, migration, adhesion, angiogenesis, Cancer stem cells, ADCC, cytokine release, etc) In vivo animal models (oncology: singenic & xenogenic, subcutaneous & orthotopic primary tumor with cell lines and clinic explants, experimental & spontaneous metastasis, angiogenesis, noninvasive imaging; acute and chronic inflammation & pain) Preclinical histology (paraffin embedding, sectioning and standard staining) Generation of monoclonal and polyclonal antibodies for basic research, diagnosis and therapy. Monoclonal antibody engineering: chimeric, humanized and biosimilars MOST RELEVANT PROJECTS 1. VACMON: biosensor for fast vaccine monitoring. PID NANOTHER: Integration of novel NANOparticle based technology for THERapeutics and diagnosis of different types of cancer, NMP NOBITAN: Novel biofocused targeting of nucleoside analogues with cyclic RGD peptides as enhanced anticancer therapy, Eurotransbio LIFE: Comprehensive challenge to breast cancer. Cenit project DENDRIA: Soluciones innovadoras para acelerar la identificación y desarrollo de fármacos en patologías del Sistema Nervioso CENIT Project MIND: Multidisciplinary Investigation of Neurodegenerative Diseases. CENIT project. CEN ONCOLOGICA: New Strategies based on biomarkers for cancer detection, prognosis, response prediction and the development of new treatments. CENIT project. CEN NANOMOLECULAR: Contrast agent with pharmacokinetics close to clinical needs and the ability to increase the resolution of a dual-energy digital mammography. NUCLI/ACC10 project PETPRO: Development of anti-angiogenic peptides using Zera technology. NUCLI/ACC10 project with Era Biotech. RD ROBIOCAT: Robotized nanobiocharacterization station. VALTEC/ACC10 project with the Electronics Department of the UB. VALTEC Biomed Division as emergent group. AGAUR project. SGR Characterization of predictive genetic models of response to anticancer drugs: systematic personalized therapeutic intervention. CDTI project with Pangaea Biotech. 13. Formulation of docetaxel nanoparticles. CDTI project with GP Pharm ROBOCELL: Robotic Station for biocaracterizacion: system optimization and development of tools and sensors to measure interaction forces in specific biomedical applications. TEC , with the Electronics Department of the UB. 15. NANOPOLYTOX: Toxicological impact of nanomaterials derived from processing, weathering and recycling of polymer nanocomposites used in various industrial applications, NMP GENIUS: Desarrollo, consolidación y explotación de plataformas tecnológicas en el proceso de descubrimiento de medicamentos innovadores. CENIT project. CEN

12 PUBLICATIONS 1. Acero N, Braña MF, Añorbe L, Domínguez G, Muñoz-Mingarro D, Mitjans F, Piulats J. Synthesis and biological evaluation of novel indolocarbazoles with anti-angiogenic activity. Eur J Med Chem. 2012; 48: Marchán S, Pérez-Torras S, Vidal A, Adan J, Mitjans F, Carbó N, Mazo A. Dual effects of β3 integrin subunit expression on human pancreatic cancer models. Anal Cell Pathol (Amst) Oct Cupido T, Spengler J, Ruiz-Rodriguez J, Adan J, Mitjans F, Piulats J, Albericio F. Amide-to-ester substitution allows fine-tuning of the cyclopeptide conformational ensemble. Angew Chem Int Ed Engl Apr 1;49(15): Mencía N, Selga E, Rico I, de Almagro MC, Villalobos X, Ramirez S, Adan J, Hernández JL, Noé V, Ciudad CJ. Overexpression of S100A4 in human cancer cell lines resistant to methotrexate. BMC Cancer Jun 1;10: Vizán, P., S. Sánchez-Tena, G. Alcarraz-Vizán, M. Soler, R. Messeguer, M.D. Pujol, W-N. Paul Lee, M. Cascante. Characterization of the metabolic changes underlying growth factor angiogenic activation: identification of new potential therapeutic targets. Carcinogenesis. 2009; 30(6): Roca, R.Messeguer R. Genómica (2009). In: Biotechnology and Drugs. Ed. Consejo General de Colegios Oficiales de Farmacéuticos. p.p Masa M. Genómica (2009). In: Biotechnology and Drugs. Ed. Consejo General de Colegios Oficiales de Farmacéuticos. p.p Piulats J, Mitjans F. Angiogenic switch pathways" in Principles of Molecular Oncology, 2007 (3d Edition), p.p Eds: Miguel H Bronchud, MaryAnn Foote. Springer Press. New York. 9. F. Mitjans, J. Piulats. Clinical implications of basic research. Angiogenesis: target new cancer treatments. Gastroenterología y Hepatología Continuada (1): Bosch B, Clotet-Codina I, Blanco J, Pauls E, Coma G, Cedeno S, Mitjans F, Llano A, Bofill M, Clotet B, Piulats J, Este JA. Inhibition of human immunodeficiency virus type 1 infection in macrophages by an alpha-v integrin blocking antibody. Antiviral Res March; 69(3): Fernandez Y, Queralt J, PAvía X, Piera C, Ramírez de Arellano I, Mitjans F, Messeguer R, Piulats J, Carrió I. Multitracer in vivo assessment of tumor models with 18F-fluorothymidine, 18FFDG and N- ammonia PET in mice. Eur J Nucl Med Mol Imaging 2006, 33 (supl II): S Enns A, Korb T, Schluter K, Gassmann P, Spiegel HU, Senninger N, Mitjans F, Haier J. Alphavbeta5- integrins mediate early steps of metastasis formation. Eur J Cancer May; 41(7): PATENTS 1. Ciudad C, Noé V, Hernández JL, Masa M, New disrupting therapeutic technology. PCT/EP2011/ Leitat Technological Center. 2. Hernández JL, Adan J, Martínez JM, Masa M, Messeguer R, Mitjans F, Dakhel S, Coll A, Hervas R, Padilla L. Antibodies for therapeutic use, target a. EP Leitat Technological Center. 3. Hernández JL, Adan J, Martínez JM, Masa M, Messeguer R, Mitjans F, Coll A, Hervas R, Calvis C, Dakhel S. S100A4 Antibodies and Therapeutic Uses Thereof. PCT/EP2011/ Leitat Technological Center. 4. Mitjans F, Adan J, Calvis C, Lavilla R, Miguel M, Albericio F, Ruiz J. Péptidos cíclicos rgd de aminoácidos basados en tiazoles u Oxazoles como antagonistas selectivos de la integrina αvβ3. WO 2012/ A1. Leitat Technological Center. 5. Goodman S, Hahn D, Mitjans F, Adan J, Lo K-M. Engineered anti-alpha v-integrin hyibrid antibodies. International Patent nº WO 2009/ A2. Merck KGaA. Goodman S, Wilm C, Mitjans F. Antibodies for the Detection of Integrin Complexes in FFPE Material. WO Merck KGaA. 12

13 NANOHEALTH & SAFETY Competency Compendium Dr. Socorro VÁZQUEZ-CAMPOS Coordinator of NanoHealth & Safety Division Equipments: Zeta Potential (Determination of stability of colloidal dispersions) DLS (Determination of size distribution of colloids in solution) BET (Determination of the surface area and the porosity of nanoparticles) UV-Vis (Optical properties of nanoparticles and particle surface functionalization evaluation) FT-IR (Characterization for the functionalization of nanomaterials) TGA (Determination of surface functionalization of nanomaterials) DSC (Analysis of physicochemical changes as degradation, oxidation, crystallinity or melting in nanofilled matrices) ICP-MS (Quantification and detection of metallic nanoparticles) Ultrasonic horn (Dispersion of nanoparticle solutions) Electrospinning (Synthesis of polymeric and ceramic nanofibers and nanocapsules) Aging chambers (Determination of migration, release or transformation of the nanofillers exposed to defined environmental conditions) Other techniques used in external facilities (TEM, SEM, XPS, XRD, CLSM, ) Facilities and equipment for in vitro and in vivo toxicological studies Characterization techniques to determine the physical and mechanical properties of nanocomposites RESEARCH ACTIVITIES Nanotoxicology (in vitro and in vivo toxicity evaluation of nanomaterials, mechanistic studies, cell internalization studies) Evaluation of physical-chemical properties of nanomaterials included in industrial products during their life cycle (from synthesis, processing, manufacturing, use, recycling, to final disposal) Accelerated aging/ weathering of products containing NM (simulation of nanomaterials/ nanocomposites use) Determination of the release of NM from complex matrices during simulating aging processes Correlation analysis of the physical-chemical properties of nanomaterials and their toxicity Design and development of novel filtration techniques for nanomaterials based on nanofiberbased filters Design and development of novel recycling and disposal techniques for nanomaterials based on nanofiber-based filtration RA/LCA analysis of nanomaterials included in commercial products Design and development of worker protective equipment for workers manipulating nanomaterial Design and development of nanobiosensors for several applications, such as, real-time vaccine and food monitoring, disease diagnostics, explosive and gas detection Synthesis and functionalization of metallic nanoparticles for biological applications Development of nanoparticle-based drug delivery systems Design of nanoparticle-based markers to study biological processes 13

14 RESEARCH EXPERIENCE Inorganic and organic nanoparticle synthesis, and characterization Functionalization of nanoparticles through covalent and biodegradable linkages to organic molecules, biomolecules, drugs... Synthesis and characterization of smart polymeric nano and microparticles by radical polymerization to obtain porous particles of different sizes using an heterogeneous polymerization (emulsion, suspension and dispersion) Encapsulation of the drug and studies about release of therapeutic agents Multi-step synthesis, purification and characterization of organic compounds Synthesis, purification and characterization of natural products with polyheterocyclic structure Analytical Skills: HPLC purification, NMR spectroscopy, MALDI-TOF and ESI mass spectrometry, UV- Vis spectroscopy, IR, bead sorting (COPAS TM technology), Edman degradation, SPR, peptide synthesizer (Syro, MultiSynTech), Circular Dichroism, flow cytometry, SEM and SEM-FIB, CLSM, TEM, AFM and STM, XPS, ζ-potential, DLS, particle size analyzer Optimization of nanomaterial dispersion protocols and characterization of dispersions for use in (eco)toxicological studies In vitro and in vivo imaging and toxicological evaluation of nanomaterials. Cell culture, micromanipulation and microinjection in reproductive cells, biokinetic and toxicological in vivo studies Evaluation of nanomaterial cell internalization pathways Cell and biomolecules characterization by means of microelectronic and microfluidic devices MOST RELEVANT PROJECTS 1. EUROTAPES: European development of superconducting tapes: Integrating novel materials and architectures into cost effective processes for power applications and magnets, NMP ; WP leader: Life cycle assessment 2. NANOMICEX: Mitigation of risks and control of exposure in nanotechnology based inks and pigments, NMP ; WP leader: Adapted streamlined life cycle/ risk assessment of nanoparticle-based inks and pigments 3. SANOWORK: Safe nano worker exposure scenarios, NMP ; WP leader: Risk analysis 4. CERAMPOL: Ceramic and polymeric membranes for heavy metal and drug water purification, NMP , WP leader: Risk assessment of nanotechnology-based membranes during their whole life cycle 5. NEXTEC: Next generation nano-engineered thermoelectric converters. From concept to industrial validation; NMP ; WP leader: Life cycle impact assessment 6. NANOPOLYTOX: Toxicological impact of nanomaterials derived from processing, weathering and recycling of polymer nanocomposites used in various industrial applications, NMP ; Coordinator 7. VACMON: Nanobiosensor for fast vaccine monitoring. PID ; Coordinator 8. NANOSOST: Towards a sustainable, responsible and secure nanotechnology. Financed by the Ministry of Industry, Tourism and Commerce. PSE ; WP Leader: Nanotechnology-based materials for barrier applications 9. ELECTROCLAY: Development and processing of conductive nanoclays to obtain multifunctional conductive polymers. Financed by the Ministry of Industry, Tourism and Commerce (2008), IAP ; Partner: Development of PANI-based nanoclays composites for conductive applications PUBLICATIONS 1. J. Vila-Planas, E. Fernández-Rosas, B. Ibarlucea, S. Demming, C. Nogués, J. A. Plaza, C. Domínguez, S. Büttgenbach, A. Llobera. Cell analysis using a multiple internal reflection photonic lab-on-a-chip Nature Protocols 2011, 29;6(10):

15 2. M. Faccini, D. Amantia, S. Vázquez-Campos, C. Vaquero, J. M. Lopez de Ipiña, L. Aubouy. Nanofiberbased filters as novel barrier systems for nanomaterial exposure scenarios J. Phys.: Conf. Ser., 2011, 304, S. Vázquez-Campos, E. Fernández-Rosas, M. Masa, F. Mitjans, L. Aubouy. Nanopolytox: Toxicological impact of nanomaterials included in polymer nanocomposites along their life cycle. Proceedings of Modern Polymeric Materials for environmental applications. 2011, 4(2), J. M. Amigo, N. G. Bastús, R. Hoen, S. Vázquez-Campos, M. Varón, M. Royo, V. Puntes. Analysis of time-dependent conjugation of gold nanoparticles with an antiparkinsonian by using curve resolution methods Anal. Chim. Act. 2010, doi: /j.aca E. Fernandez-Rosas, R. Gómez, E. Ibañez, L. Barrios, M. Duch, J. Esteve, J. A. Plaza, C. Nogués. Internalization and cytotoxicity analysis of silicon-based microparticles in macrophages and embryos Biomedical Microdevices 2010, 12(3): E. M. Campo, M. J. Lopez Martinez, E. Fernandez, L. Barrios, E. Ibañez, C. Nogués, J. Esteve, J. A. Plaza. Focus ion beam micromachined glass pipettes for cell microinjection Biomedical Microdevices 2010, 12(2): B. Ibarlucea, E. Fernandez-Rosas, J. Vila-Planas, S. Demming, C. Nogues, J. A. Plaza, S. Büttgenbach, A. Llobera. Cell screening using disposable photonic lab on a chip systems Analytical Chemistry 2010, 82(10): W. Xu, M. Dong, H. Gersen, S. Vázquez-Campos, X. Bouju, E. Laegsgaard, I. Stensgaard, M. Crego- Cálama, D. N. Reinhoudt, T. R. Linderoth, F. Besenbacher. Exploring the transferability of large supramolecular assemblies to the vacuum-solid interface Nano Res. 2009, 2, M. J. Lopez Martinez, E. M. Campo, D. Caballero, E. Fernandez, A. Errachid, J. Esteve, J. A. Plaza. Versatile micropipette technology based on deep reactive ion etching and anodic bonding for biological applications J. Micromech. Microeng. 2009, E. Fernandez-Rosas, R. Gómez, M. Duch, J. Esteve, E. Ibañez, L. Barrios, C. Nogués, J. A. Plaza. Intracellular Polysilicon Barcodes for Cell Tracking Small 2009, 5(21): Oral and Poster Presentations ( ) 1. E. Fernández-Rosas, G. Janer, M. Busquets, V. Puntes, S. Vázquez-Campos. MWCNT polymer nanocomposites: Migration and/or release of nanoadditives in polymeric matrices during aging processes NanoImpactNet-QNano conference (Dublin), 27 February - 2 March Oral presentation. 2. E. Mas del Molino, G. Janer, E. Fernández-Rosas, R. Hernández, S. Vázquez-Campos. In vitro toxicity assessment of pristine and functionalized nanoparticles Annual IVTS Meeting (Liverpool), 8 and 9th November Oral Presentation. 3. G. Janer, E. Fernández-Rosas, R. Fernández, S. Vázquez-Campos. In vitro toxicity assessment of functionalized and aged nanoparticles. 6 th International Conference on Environmental Effects of Nanoparticles and Nanomaterials. London (United Kingdom), September Poster Presentation. 4. Socorro Vázquez-Campos. Nanosafety Cluster Meeting, Budapest (Hungary), 30 th May Oral Presentation on Outcomes of the Nanosafety Cluster meeting in Barcelona 5. Socorro Vázquez-Campos. Life Cycle Assessment of Nanomaterials in Polymer Nanocomposites: Nanopolytox approach. ENPRA Workshop: Challenges of regulation and risk assessment of nanomaterials, Ispra (Italy), May Oral Presentation. 6. Socorro Vázquez-Campos, María Blázquez. Life Cycle Analysis of Nanomaterials: An overview. Imaginenano Conference. Bilbao (Spain), April Oral Presentation. 7. Socorro Vázquez-Campos, María Blázquez. Nanosafety Cluster Meeting, Lausanne (Switzerland), 17 th February Oral Presentation on Review of WG3 activities on LCA 15

16 ANALYTICAL CHEMISTRY Competency Compendium Aleix CONESA Coordinator of Analytical Chemistry Division Equipments: ICP-MS Agilent 7500 Gas chromatography - GC-MS (with Headspace, Purge and trap, Thermal Desorption and SPME) Varian Saturn Micro CG (for Biogas analysis)- Varian 490-PRO Liquid Chromatography - HPLC-PDA - Varian ProStar - HPLC UV / FLD - Waters UPLC-SQD Waters ACQUITY - HPLC TQ: Waters 2795 Quattro Micro - UPLC-TQ - Waters Acquity -Xevo TQ-S - HPLC- Q-TOF - Agilent 1100 ABSciex QSTAR Elite - UPLC- Q-TOF - Waters Acquity - Synapt QTOF - Size Exclusion Chromatography (GPC) Agilent 1200, Varian 390-LC with Light Scatterig and Refractive Index detectors - Dionex ICS3000 (with conductivity and electrochemical detectors) Total Organic Carbon (TOC) Shimadzu V-C DCH Nitrogen Kjeldahl Buchi Kjelfelx K-360 UV-Vis (with Peltier) Shimatzu UV2450 FTIR-ATR Shimadzu Affinity Elemental Analysis EuroVector EA3000 Microwave CEM Mars Differential Scanning Calorimetry (DSC) TA Instrument Q50 Thermogravimetry (TGA) TA Instrument QS500 Karl Fisher Metrohm KF 831 Automatic Titration Chemistry laboratory Metrohm 809 Titrando and 814 USB 16

17 SPECIFIC RESEARCH INTERESTS Analytical method development and validation. Detection, quantification and valorization of high added value products from residues and feedstock: Biorefinery, algae, etc. Detection and quantification of nanoparticles. Determination of different kind of pollutants in several matrices like water, soil and others. Soil analysis. Drug quantifications in blood and other biological fluids. Waste characterization. Metal detection and quantification by ICP-MS. Chemical resistance of materials and barrier properties. REACH Assessment. Substitution of High Concern Substances: Green Chemistry. Study and definition of exposure scenarios of chemicals. Biodegradability assays (OECD official methods). Chemical analyses for ECOLABEL certification. MOST RELEVANT PROJECTS 1. BIOCONCEPT, Towards a sustainable bio-industry - Biotechnology for renewable chemicals and innovative downstream processes, KBBE ITACA, Investigación de tecnologías de tratamiento, reutilización y control para la sostenibilidad futura de la depuración de aguas, Innpronta. 3. BIOALGAL, Biological compounds obtained by microalgal innoative extraction processes, RDNET PHYLIRA, Study of malodor after washing on wet textiles. 5. FERRARID, Sustainable and high performance aggregates for 21st century. Collaborative projects of research and development destined to creat innovation nucleus, RDITCCON Development of informatics tools to support the evaluation of the chemical safety according REACH in the manufacturing packaging processes. REACH PACK, national program Call of experimental development- technological center subprograms. REA-09-AC Research on detection and control of toxic products in textile sector. Profit CT, Ministerio de Industria, Turismo y Comercio. FIT G / ECOMETRE (Ecological Metal Recovery). European Project: CIP-EIP-Eco-Innovation-2008, June 2009-November Investigation of alternative technologies for industrial wastewater treatment. Nacional Project: Ministerio de Industria, Turismo y Comercio; LIA CT Ref: DEX Treatment and waste valorization from a pharmaceutical company. Industrial Project Research in Healthy Foods and Products.(INVIAS). CDTI project with Grup Lasem. IDI NANOPOLYTOX: Toxicological impact of nanomaterials derived from processing, weathering and recycling of polymer nanocomposites used in various industrial applications, NMP , BIOLUB, Obtention of high performance and environmentally friendly lubricant bases, 09-PR Study of dyes and auxiliaries in historical textiles. 17

18 PUBLICATIONS 1. Exposición: COLORES DEL MEDITERRANEO. Colorantes naturales para un textil sostenible? del 21 de diciembre de 2010 hasta finales de Lugar: Centre de Documentació i Museu Tèxtil de Terrassa. 2. Monterrat Bargalló, Meritxell DelaVarga, Lorenzo Bautista, Albert Briz, Laurent Aubouy (November 2007). Dyes from yesterday, colours for tomorrow, Datatèxtil, 16: Aleix Conesa, Lorenzo Bautista, Roshan Paul, Laurent Aubouy, Meritxell DelaVarga. "Dyes from yesterday, colours for tomorrow: of the history to the new technologies, Datatèxtil, 19, 60-75, Leitat Technological Center. "REACH, a great challenge for industry. Pre-register time, Magazine 3G Empresarial Girona, Octubre Leitat Technological Center, Does REACH leads to residues valorization and recycling?, Revista de Plásticos Modernos, 627, September Meritxell De la Varga, Montserrat Bargalló. Dyes from yesterday, colours for tomorrow, II Mostra de Coneixement, oral communication, 19 de October 2006, Terrassa. 7. The role of the technological centres and REACH, Meritxell De la Varga, Oral communication Impacto y Gestió de REACH en la Industria workshop. Barcelona. 30 November Recommendations for SIEF constitution, Alejandra Sánchez Yagüe, Oral communication, Impacto y Gestió de REACH en la Industria workshop. Barcelona. 30 November "Obligations derived from REACH for the textile industry" workshop in the Textile Industrial Association of the Cotton Process (AITPA). Barcelona. 4 June D. Amantia. Nanoparticles release from textiles Carbon nanotube coating as experimental approach, NanoImpactNet Workshops Strategies to standardize nanomaterials for environmental and ecotoxicological research, Conference, ETH Zurich (Switzerland), 3-5 setembre Practical exercise: preregister of chemical substances", in the Informative Conference REACH: Preregister, organized by Commerce Chamber of Terrassa. 4 November 2008, Marta Escamilla, Oral Communication. 12. REACH in practise workshop "Obligations for the sector" organized by Asociación Española del Género de Punto, Natalia Fuentes. Oral Communications. Barcelona. 17 December Meritxell De la Varga, REACH in Catalonia and Technological Centres role, Oral Communication, Congress: European Chemicals Region Network / REACH Workshop, Aachen (Germany), José Moltó, Asunción Blanco, Cristina Miranda, José Miranda, Jordi Puig, Marta Valle, Meritxell DelaVarga, Carmina R Fumaz, Manuel José Barbanoj, Bonaventura Clotet. Variability in antiretroviral agents concentration in plasma among hiv-infected adults in routine clinical practice, British Journal of Clinical Pharmacology, 62, , José Moltó, Asunción Blanco, Cristina Miranda, José Miranda, Jordi Puig, Marta Valle, Meritxell DelaVarga, Carmina R Fumaz, Manuel José Barbanoj, Bonaventura Clotet, Lopinavir/Ritonavir Pharmacokinetics in HIV and Hepatitis C Virus Co-Infected Patients without Liver Function Impairment: Influence of Liver Fibrosis, Clinical Pharmacokinetics, 46, 85-92,

19 FAST MOVING CONSUMER GOODS Competency Compendium Dr. Miquel OSSET Coordinator of the FMCG Division Main research fields: Laundry & Home Care. Equipments: Hard Surface Scrub Testers Washing Machine Testing Facilities Textile Testing equipments Storage & Stability Areas Humidity & Temperature Probes Injection moulding Tensiometers and Rheometers Sun Test & Xenon aging chambers UV-climatic aging chambers Viscosimeters Optical microscopy SPECIFIC RESEARCH INTERESTS Laundry Testing: o Primary & Secondary washing performance tests o Textile testing o Wash & wear studies o Ecolabel o Physical-chemical characterizations o Stability testing Hard Surface Testing: o Scrub & Abrasion Surface Testing o Shine, foaming, easy rinse, quick & dry profiles o Optimization of formulations o New surfactants o Assessment of Hard Surface Cleaners o Stability testing Consumer Goods Product Development: o Assessment of raw materials suppliers o Soil release effects 19

20 o Competitor benchmarking o New formulations and ingredients Hygiene and Disinfection in Consumer Goods: o Disinfection & Biocides acc. to EN Norms o Hypochlorite-based formulations o Peroxide-based Laundry Additives o Long Lasting Hygiene o Corrosion and irritancy reduction o Assessment of Biocides Packaging Technologies: o Primary Packaging optimizations o Secondary Packaging optimizations o Materials Testing o Graphic & Industrial Design o Life Cycle Analysis of CPGs Consumer Packaged Goodso Carbon Footprint of CPGs Consumer Packaged Goods- R&D management in Fast Moving Consumer Goods: o R&D Strategy (OGSMs, Balance Scorecards, Roadmaps, etc...) o Management of high performance teams o R&D Financials o Key Performance Indicators for R&D o Consumer Insights MOST RELEVANT PROJECTS 1. CENIT SEILA New Technologies for an efficient, ecologic and intelligent washing system for the future textiles , CEN PET-Bleach: PET Bottles for highly oxidizing Bleaches RD EU Ecolabel. Laundry Detergents Performance testing /2009/54965/SER/G1 4. EU Ecolabel. Dishwashing Performance Testing Barcelona Institute of Packaging ( ): project management and implementation of tools & practices 6. Product Development of Biocides ( ) 7. Product Development of solid laundry additives ( ) 8. Microbiological characterization on textiles (Henkel KGaA ) 9. Characterization of Cleaners (KH-Lloreda 2010) 10. Product Development of Industrial Degreassers (Henkel KGaA ) 11. Product Development of Bleaches ( ) 12. Analytics of raw materials in detergency: on-going. 20

21 PUBLICATIONS 1. Detergency for high added value textiles (CED, Barcelona 2010). 2. Study of the interaction of commercial surfactants on new textile products (Dornbin 2010). 3. Formulation of super-concentrated liquid detergents -Draft- (CED, Barcelona 2011). PATENTS 1. US B1 Active chlorine preparations containing stabilized optical brighteners. 2. US A Formulations for cleaning hard surfaces comprising a betaine surfactant having exactly 12 carbon atoms. 3. US A Detergent mixtures. 4. US A Low-foaming cleaning formulations. 5. US A Aqueous bleaching formulations. 6. WO A1 Stability improvement of liquid hypochlorite-containing washing and cleaning compositions. 7. WO A1 Increasing the stability of liquid hypochlorite-containing washing and cleaning compositions. 8. WO A1 Odour reduction for agents contaning hypochlorite. 9. WO A1 Inhibiting the corrosive properties of liquid cleaning agents containing hypochlorite. 10. WO A1 Hand Dishwashing Detergent. 11. WO Improving the stability of detergents containing hypochlorite. 12. WO A1 Improving the stability of detergents containing hypochlorite. 13. WO A1 Liquid hypohalite bleach. 14. WO A1 Bleaching and disinfecting agents. 15. WO A1 Bleaching and disinfecting agents. 16. WO A1 Active chlorite-containing preparations with stabilized fragrances. 17. WO A1 Peroxy-containing preparations with stabilized fragrances. 18. WO A1 Peroxide-contaning preparations with stabilized optical brightening agents. 19. WO A1 Aqueous dispersions of anionic and cationic surfactants. 20. WO A1 Bleaches and Disinfectants. 21. DE A1 Reinigungsmittel für harte Oberflächen. 21

22 NANOMATERIALS Competency Compendium Dr. David AMANTIA Team leader of Nanomaterials Unit Equipments: Electrospinning setup MECC NF103 Series Ultrasonic horn SONICS 20kHz Potential Z, DLS ICP-Mass B.E.T. surface area and pore size analyzers QUANTACHROME Nova e-series 2200 Conventional chemical characterization UV-Vis, FTIR-ATR, HPLC. Pyrolysis furnace N 2, Ar. Tensiometer Tween screw extruder for polymeric nanocomposite Injection moulding Other techniques used in external facilities (TEM, SEM, XPS, XRD, TGA ) Physical and mechanical properties characterization of nanocomposites SPECIFIC RESEARCH INTERESTS Chemical Modification and Production of Nanoparticles Functionalization of carbon nanotube, organic modification of nanoclay, synthesis of magnetite nanoparticle (Fe 3 O 4 ). Nanofiber by Electrospinning Production of aligned and randomly organized polymeric (PAN, PA, PS, Cellulose...) or ceramic (LiCoO 2. LiFePO 4, TiO 2, SiO 2...) nanofibres. Core-shell nanofiber. Carbon nanofiber Production of nanofibrous membrane for water treatement. New Nanocomposite Compounding of nanoclays, nanoparticles and carbon nanotubes in polymeric blends for automotive parts. Functionalization of Textiles Through innovative surface treatments (Sol-Gel, Plasma polymerization, grafting of chemically modified nanoparticle). Multifunctional and Smart Materials Thermochromic and phosphorescent polymer blend, nanoencapsulation by electrospraying and microemulsion procedure. 22

23 MOST RELEVANT PROJECTS 1. CERAMPOL. Ceramic and polymeric membrane for water purification of heavy metal and hazardous organic compound. 7 th framework program Collaborative project [NMP ] Grant agreement no: nauto2. Nanomaterials for automotive industry. Línia d ajuts a projectes de NUCLIS COOPERATIUS de Recerca Industrial i Desenvolupament Experimental 2010 Financed by ACC1O 2010 RD NANOTHERM. Tailoring electronic and phononic properties of nanomaterials: Towards ideal Thermoelectricity. technical programme of the research activity consolider-ingenio 2010 CALL CSD ETF- Energy Technology Future. New concepts for energy storage for medium and large scale applications. PID SUPERCAP Research and development of new supercapacitors based on electrochemical double layer and pseudocapacitative effects. 6. NANOPOLYTOX: Toxicological impact of nanomaterials derived from processing, weathering and recycling of polymer nanocomposites used in various industrial applications, NMP Development of flexible upholstery based on fire resistant nanoclays. Financed by the Ministry of Industry, Tourism and Commerce (2008). IAP Applying carbon nanotube for advanced mechanic properties of protection textile. Financed by the Ministry of Industry, Tourism and Commerce (2008). NAN E. 9. Electroclay: Development and processing of conductive nanoclays for obtention of multifunctional conductive polymers. Financed by the Ministry of Industry, Tourism and Commerce (2008). IAP Nanocit: Design of high added value product based on carbon nanostructure and polymeric resin. Financed by the Ministry of Industry, Tourism and Commerce (2008). IAP Nanotech: Development of conducting fibres of high resistance using polymers and carbon nanotubes. Financed by the Ministry of Industry, Tourism and Commerce (2008). FIT Application of nanotechnology for improving mechanical properties of antistatic and fireproof fabrics. Financed by the Ministry of Industry, Tourism and Commerce (2007). TEX Nanocotton: Application of nanotechnology in textiles for UV protection. Financed by the Ministry of Industry, Tourism and Commerce (2007). TEX PUBLICATIONS 1. Development of protective clothing against nanoparticle based on electrospun nanofibers Mirko Faccini, Celina Vaquero, David Amantia. Journal of Nanomaterials In Press. 2. Nanofiber-based filters as novel barrier systems for nanomaterial exposure scenarios M Faccini, D Amantia, S Vázquez-Campos, C Vaquero, J M López de Ipiña and L Aubouy Journal of Physics: Conference Series, 304, , Nanofibras y nanoweb por proceso de electrohilatura Mirko Faccini, David Amantia. Revista de Química e industria textil (AEQCT), nº 196 enero-marzo Reactions of Pd(II) with Chelate-Tethered 2,6-Diaminopurine Derivatives: N3-Coordination and Reaction of the Purine System. Galindo MA, Amantia D, Martinez-Martinez A, Clegg W, Harrington RW, Moreno Martinez V, and Houlton A. Inorganic chemistry 48(23): , Probing metal-ion purine interactions at DNA minor-groove sites Galindo MA, Amantia D, Martinez Martinez A, Clegg W, Harrington RW, Moreno Martinez V, and Houlton A Inorganic chemistry 48(21): ,

24 6. Self-assembly of a bis(adeninyl) Cu(I) complex: a cationic nucleobase duplex mimic. Miguel A. Galindo, David Amantia, William Clegg, Ross W. Harrington, Richard J. Eyre, Jonathon P. Goss, Patrick R. Briddon, William McFarlane and Andrew Houston. Chem. Commun., 2009, Polyethylene - Montmorillonite Nanocomposite Fibres: Preparation and Properties Poster presented in NanoEurope September 2007 (St.Gallen, Switzerland). 8. Nano-finishing of cotton yarns and fabrics, Paper presented in CLOTECH 2008, June 2008 (Lodz, Poland). 9. Miguel A. Galindo, David Amantia, William Clegg, et al. Self-assembly of a bis(adeninyl) Cu(I) complex: a cationic nucleobase duplex mimic Chem. Commun., 2009 First published on the web 2nd March Cerda, MM; Amantia, D; Costisella, B, et al. Multiple metal binding to 6-oxopurine nucleobases as a source of deprotonation. The role of metal ions at N7 and N3. DALTON TRANSACTIONS. Issue: 32 Pages: , Amantia, D; Shipman, MA; Price, C, et al. Conserved supramolecular architecture in polymetallic nucleobase complexes. INORGANICA CHIMICA ACTA. Volume: 359. Issue: 11 Pages: Published: AUG PATENTS 1. P Pere Llobet Padro, Miquel Osset Hernández, David Amantia, Mirko Faccini, Albert Almarza Martínez, Minerva Fernandez Blanco. 2. ES Roshan Paul, David Amantia, Lorenzo Bautista, Moises Moron, Helena Esteve, Marolda Brouta, Jordi Mota, Meritxell De la Varga. 3. ES P David Amantia, L. Aubouy, J. Jiménez Romero, Anna Ribé. ORAL AND POSTER PRESENTATIONS ( ) 1. Advanced nano-materials for automotive industry, IMAGINENANO 2011, Bibao SPAIN, 11-14th of April Poster 2. Design of high added value products based on carbon nanostructure and polymeric rope and tow strap, NANOMATERIALS FOR INDUSTRY, Santander SPAIN, 31st of March Applications of nanofiber in energetic and environment sectors, 5th open day of technological offer in Catalonia, Manresa SPAIN, 25th of March Environment-friendly materials for aeronautic applications, OPEN CHINA-EUROPE WORKSHOP ON AERONAUTICS RESEARCH, Nanjing, CHINA, 25-28th of November Protective Textile Materials Based on Electrospun Nanofibers, 49th DORNBIRN MAN-MADE FIBERS CONGRESS. Dornbirn AUSTRIA, 15-17th of September Nanofiber-based filters as novel barrier systems for nanomaterial exposure scenarios, NANOSAFE Grenoble FRANCE, 16-18th of October

25 ADVANCED POLYMERS Competency Compendium Dr. Meritxell MARTÍNEZ-PALAU Coordinator of Advanced Polymers Division Equipments: Twin screw extruder Extrusion Microcompounder Mould microinjection machine Mould injection machine Melt spinning Monofilament unit Polymerization reactor Other facilities: Portable Drying Conveyors Triturating mill Differential scanning calorimetry (DSC) Thermogravimetric analysis (TGA) Gel Permeation Chromatography (GPC) Gas Permeabilimeter Tensile tester Charpy impact equipment Melt flow index / Viscosimeter Fire resistance testing equipment Weathering equipment FTIR-ATR UV visible Optical microscopy SPECIFIC RESEARCH INTERESTS Synthesis o Biopolymers o Biodegradable polymers o Smart polymers (Shape Memory- Electrochromic-Conductive) Compounding o Polymers with natural fillers (woods, cellulose, bamboo ) o Smart polymers (chromic luminiscent PCM) o Polymers with nano fillers (nanotubes nanoclays nanoparticles - nanospheres) o Active polymers/biosensors o On demand service Recycling o Recycling cycles o Raw/recycled blends o Use of out-of-use scraps as polymer fillers 25

26 Polymerization and crystallization kinetics studies Polymeric microspheres for controlled drug release Examples of know-how: Biodegradable composites from biopolymers and natural fillers Development of electrically conductive polymers and fibers Development of wood-plastic composites (WPC) Development of thermochromic polymers Development of luminescent polymers and fibers Development of new HDPE composites with high oxygen barrier Development of new PP composites with high flame resistance MOST RELEVANT PROJECTS 1. Valorization and recycling of industrial and post-consumer coffee capsules waste. Industrial project with Nestlé. 2. Development of WPC with antimicrobial behavior. Industrial project with Ercros. 3. Electrical conductive composites based in PVC formulation. Industrial project with Ercros. 4. Study of the viability of uses of PET residues as reagent for adhesive formulations. Industrial project with Henkel. 5. Screening, research and development of new PIPA applications. Industrial research with Cepsa. 6. Lightmotorcycle project: Towards a lighter endure and trial competition motorcycle by means of light composites. R+D projects, Cooperative Nucleus R+D+i RD nauto2 project: Nanotechnology for Automotive applications. R+D Projects, Cooperative Nucleus R+D+i RD SUPERTEX, Sustainable Flame Retardant Technical Textile from Recycled Polyester. European project: Eco-innovation 2011 ECO/10/277225/SI GREEN-UP, Improvement of the recycling polyester and leather tanning processes for products focused on the accomplishment of automotive recyclable upholstery. European project: Eco-innovation 2010, ECO/09/256111/SI CENIT TARGET: Tecnologías inteligentes y medioambientalmente sostenibles para la generación de estructuras en materiales compuestos. CENIT 2010, CDTI. 11. Development of new composites based on white slags from fundition. Industrial project with Copcisa. 12. PETBleach, PET Bottles for high oxidizing Bleaches ACCIÓ, R+D Projects, Cooperative Nucleus R+D+i, RD Multi.Matheria, Ministry of Science and Innovation, LIA Singular and Strategic Projects, PSE CENIT BioSos, Sustainable Biorefinery, Ministry of Science and Innovation, National Strategic Consortium Project in Technical Research (CENIT), 2009.CEN BoatCycle, Management, recycling and recovery of wastes of recreational boat scrapping, LIFE 08 ENV/E/ PETAUTO: Development of new and multifunctional PET composites with new properties. CIDEM. RD Development of new concentrated biodegradable colour masterbaches. Ministry of Industry, Tourism and Trade. IAP Development of new films with advanced properties of barrier effect using modified nanoclays. Ministry of Industry, Tourism and Trade. IAP

27 19. Investigation and development of conducting fibres of high resistance through the use of polymers and carbon nanotubes. Ministry of Industry, Tourism and Trade. FIT Advanced Biofibres, Financed by Ministry of Industry, Tourism and Trade. FIT PUBLICATIONS 1. Martínez-Palau, M.; De La Fuente, M.; García, A.; Pérez, G.; Sacristán, M.; Ascanio, Y.; Aubouy, L. Desarrollo de nuevos materiales con propiedades barrera a partir de nanocargas funcionales. Revista de los plásticos modernos. Marzo De La Fuente, M.; Martínez-Palau, M.; García, A.; Sacristán, M.; Aubouy, L. Proyecto PETAUTO: Desarrollo de nuevos composites de PET con altas propiedades para piezas de Automoció. Revista de los plásticos modernos. Noviembre De La Fuente, M.; Martínez-Palau, M.; García, A.; Piñol, L.; Sacristán, M.; Aubouy, L. Nuevos composites madera-plástico a partir de residuos náuticos. Revista de los plásticos modernos. Diciembre Martínez-Palau, M; De La Fuente, M.; Briz, A.; Valero, J.; Garrido-Franco, M.; Paul, R.; Bautista, L.; García-Montaño, J.; Amantia, D.; Aubouy, L.; De La Varga, M. (2009). Nobel Biofibres from Biodegradable Polymers and Natural Fibres, Naro.Tech, Erfurt (Germany). 5. M. de la Fuente, A. Briz, J. Valero, M. Garrido-Franco, R. Paul, L. Bautista, J. García-Montaño, D. Amantia, L. Aubouy, M. de la Varga (2008) Novel Biofibres from Biodegradable polymers and cellulosic fibers. 7th Global WPC and Natural Fibre Composites Congress and Exhibition, Kassel (Germany). 6. M. de la Fuente, A. Briz, L. Bautista, J. Mota, R. Paul, L. Aubouy, M. de la Varga, M. Garrido. (2007) Polyethylene-Montmorillonite Nanocomposite Fibres: Preparation and Properties Nanoeurope, St. Gallen (Switzerland). Conference Presentations 1. De La Fuente, M.; Martínez-Palau, M.; García, A.; González-Vidal, N.; Piñol, L.; Aubouy, L. Development of novel Wood Plastic Composites (WPC) using as natural filler wood from the recycling of leisure sailing ships. 3rd International Conference on Innovative Natural Fibre Composites for Industrial Applications. Roma (Italy) October Ángel García. Presentació del projecte BOATCYCLE. Saló Nàutic Internacional de Barcelona. Barcelona. 11 November Ángel García. Seminari " NUEVOS HORIZONTES PARA LOS RESIDUOS DE ORIGEN PESQUERO Y PORTUARIO". Casa Llotja de Mar (Barcelona), 22th November De La Fuente, M.; Martínez-Palau, M.; García, A.; González-Vidal, N.; Piñol, L.; Aubouy, L. Development of novel Wood Plastic Composites (WPC) using as natural filler wood from the recycling of leisure sailing ships. Eurotec Conference 2011 (Barcelona), 14 th November García, A.; Paul, R.; De La Fuente, M.; Martínez-Palau, M.; González-Vidal, N.; Brouta, M. Thermal stress sensoring system in personal protection equipments for emergency situations. SMARTEX Kafrelsheikh (Egypt), November Mercè de la Fuente. Investigation and development of novel conductive fibers with high resistance properties, MFC 2009, Dornbin (Germany). 7. Mercè de la Fuente, Boatcycle: Management,recycling and recovery of wastes of recreational boat scrapping, Save the Planet Conference 2010, Sofia (Bulgary). PATENTS 1. PCT/ES2010/070105, New PET composites, L. Aubouy, M. Martinez, G. Sandoval, M. de la Fuente, A. Garcia. 27

28 SURFACE TREATMENTS Competency Compendium Eng. Lorenzo BAUTISTA Coordinator of Surface Treatments Division Equipments: Low-Pressure Plasma (vacuum) and Atmospheric-Pressure Plasma systems (plasma jet, APGD, ADRE) Paint booth + paint box Spray drier High speed disperser / Homogenizer / Emulsifier Spray coating, bar coating, spin coating systems Screen printing, pad printing and inkjet printing systems Ozone gas equipment UV curing systems Ultrasound equipment Hot plate press for hot melt lamination Tensiometer and ink test: contact angle and surface tension Viscosimeters (Brookfield, Ford viscosity cups) Density of paints, coatings and inks Spectometer UV-Vis Spectraflash (colour density, opacity, yellowing, etc.) Particle size and fineness of grind for paints, pigments, inks, coatings, etc. (Nano)particle size and distribution (DLS), Z-potential BET surface area and porous size analyser FTIR-ATR (ATR Ge crystal) and UV-Visible spectrometers Adhesion and peeling tests Air permeability testers / Water permeability analyzers / Vapour permeability Heat transmission rate analyzer Electrochemical characterization equipment Microscopy Laboratory Microbiological Laboratory Mechanical, thermal, rheological and electrostatic analysis of coated and painted materials Accelerated ageing of coated materials SPECIFIC RESEARCH INTERESTS Paints, coatings and printing inks: o o o Technologies: liquid or powder coatings, printing inks, nanocoatings by PECVD processes, grafting induced by plasma, sol-gel coatings. Formulation: solvent or water-borne coatings, dispersion of pigments (Cowles, ball milling), rheological properties, wetting properties, green solvents, role of additives;. Application: paint booth with temperature control. 28

29 o o Drying/curing: UV or thermal. Properties: hydrophobic, oleophobic, hydrophilic, oleophilic, antimicrobial, UV protection, barrier properties, abrasion resistant, self-cleaning, anticorrosion, thermal resistance, electrical conductivity, IR reflecting, thermochromic and photoluminescent, among others. Microencapsulation technologies: o o o o o Why?: to avoid the degradation of the core, masking odors, protecting the core during the processing, controlled-release, self-healing paints and coatings. Microencapsulation methods: chemical (coacervation, emulsion, etc.) and physical (spray drying) methods. Core: flavors, biocides, pigments, enzymes, vitamins, etc. Shell: polyamide, chitosan, gelatin, ethyl cellulose, etc. Industrial sectors: food, cosmetic, pharmaceutical, textile, plastics, aeronautical, detergency, building, etc. Preparation of surfaces: o o Technologies: degreasing, surface pretreatments, plasma, ozone. Properties: wetting and adhesion improvements before painting, coating, printing, laminating, gluing, etc. Decontamination of surfaces: o o Technologies: plasma, UV radiation, ultrasounds, ozone, photocatalysis. Properties: elimination of microorganisms (bacteria, fungi, yeast). Chemical and morphological surface analysis: FTIR-ATR, SEM, static and dynamic contact angle. MOST RELEVANT PROJECTS 1. PIRECO: New formulations of paints and coatings with high antiadherence properties for external parts of cars, R+D+i Cooperative 2009, ACCIÓ, RD SEILA: New technologies for an efficient, ecological and intelligent textile washing system for the future, CENIT 2009, CEN INSEPLATEX: Development of functional plastics and textiles with repellent and insecticide effects, R+D+i Consorciado 2009, ACCIÓ, PID ECOMOVIN: Alternative ecofriendly materials for the interior of transport systems, R+D+i Cooperative 2009, ACCIÓ, RD ADRESURFOOD: Investigación y Desarrollo de la Tecnología ADRE para el Control Higiénico en Superficies Alimentarias, MITYC, Invest In Spain 2010, , ID: C1_10_ MICROSEGA: Microcápsules biopolimèriques per aplicacions de seguretat alimentària, AGAUR, Valor 2010, MICROFLEX: Microfabrication technologies for flexible substrates, NMP , CP-IP , AMICOAT: Antimicrobial nanostructured durable coatings for fuel tanks, Clean Sky 2011, ZOOBIOTECH: Aplicació d extractes derivats de cultius de cèl lules vegetals meristemàtiques modificats mitjançant tractaments biotecnològics, Eurotransbio 2011, BIP: Modificació superficial de packaging i tintes intel ligents (subactuació 2), Plans d actuació d agents TECNIO 2001, ACCIÓ,

30 11. ITACA: Investigación de tecnologías de tratamiento, reutilización y control para la sostenibilidad futura de la depuración de aguas, INNPRONTA 2011, INNOFOTO: Novel immobilised photocatalysts for polluted air treatment, Proyectos de Investigación Fundamental no orientada 2011, CIEMAT-UPM-LEITAT, PUBLICATIONS 1. L. Bautista. Aplicación de AFM en la caracterización superficial de recubrimientos textiles basados en tecnología de plasma y sol-gel, I Jornadas de Microscopia de Sonda Próxima Aplicada a Empresas, Barcelona, Lorenzo Bautista, Laia Crespo, Jordi Mota, Meritxell de la Varga. Nanorrecubrimientos basados en tecnología de polimerización por plasma, Jornada AIN 2010 Barcelona, L. Bautista et al. Effect of the type of gas and temperature during atmospheric pressure glow discharge treatments on LDPE films, Plasma Surface Engineering (PSE 2010), Garmisch-Partenkirchen, Germany, September 13-17, Helena Esteve, Marolda Brouta, Laia Crespo, Roshan Paul. Desarrollo de textiles con valor añadido mediante microencapsulación, Revista de Química e Industria Textil, 197: 58-59, Llorenç Bautista, Jordi Mota, Laia Crespo, Meritxell de la Varga, Atmospheric Pressure Plasma technology for textile applications, 37 Simposium de la AEQCT, 6-7 June 2011, Barcelona (Spain). 6. L. Crespo, A. Serret, R. Paul, L. Bautista, H. Esteve, M. De la Varga, A. Surribas, Synthesis and characterization of antibacterial chitosan microspheres for textile applications, XIX International Conference of Bioencapsulation, 5 August 2011, Amboise (France). 7. Jordi Mota, Laia Crespo, Llorenç Bautista, Research and devolopment of bio-based chemistry in Leitat, Eurocoat 2011, September 2011, Paris (France). 8. L. Bautista, M. Batsiolas, J. Mota, L. Crespo, M. de la Varga, R. Paul, Ch. Pavan, Surface-modıfıed polyester filters by APGD treatments, 50th Dornbirn MFC, September 2011, Dornbirn (Austria). 9. R. Paul, M. Osset, M. Fernández, L. Bautista, J. Mota, L. Crespo, M. Faccini, A. Machin, C. Malet, Interaction of surfactants on new textile products, Melliand China, 2011, 10: M. B. Della Pirriera, P. Bosch-Jimenez, L. Aubouy, D. Gutiérrez-Tauste, J.M. García-Torres, J.L.Bautista. DSSC with large stokes shift layer as UV blocking layer, 4th international Conference on Hybrid and Organic Photovoltaics (HOPV2012), 6-9/5/2012, Uppsala (Sweden). 11. M. B. Della Pirriera, P. Bosch-Jimenez, E. Torralba, D. Gutiérrez-Tauste, D.Amantia, M.Faccini, L. Bautista, J.M. García J. A. Saez, F. Agustí, Eu photolumiscence paste for PV, Proceedings Largearea Organic & Printed Electronics Convention (LOPE-C 2012), June 19-21, 2012, München (Germany). 12. L. Bautista, J. Mota, L. Crespo, J. M. García, M. Martínez, L. Aubouy, "Poly(acrylic) nanocoatings deposited by AP-PECVD processes on paper substrates for packaging applications", Plasma Surface Engineering (PSE 2012), September 10-14, 2012, Garmisch-Partenkirchen (Germany). PATENTS 1. L. Aubouy; L. Bautista; E. Crespo; J. Pla; P. Andrés. Revestimiento de cromatismo variable para la decoración de superficies P Roshan Paul, David Amantia, Lorenzo Bautista, Moisés Morón, Helena Esteve, Marolda Brouta, Jordi Mota, Meritxell De la Varga. Tejidos funcionalizados con nanotubos de carbono, Marina Textil S.L., PCT/ES

31 TEXTILE TECHNOLOGIES Competency Compendium Eng. Javier JIMENEZ Coordinator of Textile Technologies Division Dr. Roshan PAUL Principal Investigator of Textile Technologies Division Equipments: Yarn winders and weaving machines Circular and flat knitting machines Dyeing and finishing machines for fibres, yarns, fabrics and garments Padding mangles and coating equipments Digital and screen printing machines Electrostatic powder spray guns Industrial thermo-sealing machine and sewing machines Hot plate press for hot melt lamination Testing equipments for chemical, mechanical and physical properties of textiles Accreditations: EXP.18LE026 Wool and textile products EXP.18LE274 Burning behaviour EXP.LE705 Personal protective equipments OC-L/023 Notified Body for PPE SPECIFIC RESEARCH INTERESTS Technical textiles: Development of technical textiles for construction, automotive, marine, aeronautical, agricultural and environmental sectors. Smart textiles: New functionalities on textiles by incorporating electronics and functional finishes. Medical textiles: Superabsorbents, medical textiles and sutures for personal use and operation theatre. Non-wovens: Geotextiles, felts and filters with functional properties. Personal protective equipments: Development, modification and applications. Nanotechnology applications: For developing multifunctional textiles: self-cleaning, UV protection, antibacterial, hydrophobic, oleophobic, antistatic, abrasion resistant, fire retardant, etc. Sol-gel finishing: Nanocoatings on textiles and non-wovens Plasma applications: Pretreatment and finishing of textiles and non-wovens. Biotechnological applications: Enzymatic pre-treatments, bio-finishing, denim washing, application of pharmaceutics, antibacterial treatments, etc. Microencapsulation: Development and application of microcapsules for fibres and textiles. Spray coatings: Liquid and electrostatic powder spray coatings and finishes. Natural products: Application of natural dyes, natural products and natural finishes. Natural fibres: Utilization bast fibres like flax, hemp, jute, pineapple, etc. for clothing and insulation. Cosmetic textiles: Application of cosmetic finishes and testing of cutaneous irritability. Textile recycling: Reuse of textile waste for technical and environmental applications. 31

32 MOST RELEVANT PROJECTS 1. CAPCARE: Natural hair dyes with lesser sensitibility, CDTI - PID Individual ALBATROS: Development of a new personal security system for sea life based on new materials that can be integrated in the on-board clothing, CDTI, IDI GREENUP: Improvement of the recycling polyester and leather tanning processes for products focused on the accomplishment of automotive recyclable upholstery, CIP Eco-Innovation-2009, ECO/09/256111/SI ECOMOVIN: Alternative eco-friendly materials for the interior of the means of transport, ACC1Ó - RD SEILA: New technologies for an efficient, ecologic and intelligent washing system for the future textiles, CENIT CEN INSEPLATEX: Development of plastics and textiles with insect repellent and insecticide effects, LIA I+D+i 2009 CONSORCIADO, PID SAFEPROTEX: High-protective clothing for complex emergency operations, FP7-NMP-2008-SME-2, PROFITEX: Providing fire fighters with technology for excellent work safety, FP7-NMP , T-POT: Unlocking the Croatian textile research potentials, FP7-REGPOT , FIBNATEX: Production and technical evaluation of natural fibres for the textile industry of the Southwest Europe, INTERREG IVB SUDOE 2008, SOE1/P1/P Improvement of whitening effect and the dyeing yield by means of the application of hydrolyzed protein on cotton and chrome tanned leather, LIA I+D+i IAP MICROFLEX: Micro fabrication production technology for MEMS on new emerging smart textiles/flexibles, NMP FP7-NMP-2007-LARGE-1, UV-TUBE: UV curable yarn finishing with carbon nanotubes to obtain yarns with good permanency of conductive properties, MNT ERA-NET Transnational Call 2007, NAN E. PUBLICATIONS 1. Paul R., et al Hydrolyzed collagen: A novel additive in cotton and leather dyeing. Dyes Pigm Paul R., et al Chapter 10. Protective insulation materials in Functional Protective Textiles, Edited by Bischof S., Published by University of Zagreb, Croatia. ISBN , pages Brouta-Agnésa M., Innovative textiles based on hemp fibres. Rev. Química e Ind. Textil Ribé A., et al PALF: New opportunities for pineapple leaf fibres. Rev. Química e Ind. Textil Paul R., et al Nano-finishing of textiles by sol-gel technique. Asia. Dyer. 8 (4) Paul R., et al Interaction of surfactants on new textile products. Mell. Inter. 17 (2) Paul R., et al Technical applications of coir fibres. Rev. Química e Ind. Textil Paul R., et al Nano-cotton fabrics with high ultraviolet protection. Text. Res. J., 80 (5), Ribé A. Saúde Project: Development of foot protection equipment for fishermen of Galicia. Rev. Química e Ind. Textil, 199, Paul R., et al Ecological dyes and mordants: A solution for the environment. Quím. Textil, 33 (100),

33 11. Esteve H., et al Development of value added textiles by means of microencapsulation. Rev. Química e Ind. Textil, 197, Ribé A., et al SAÚDE Project for improving the work conditions. Rev. Inno. Textil, 8, Brouta M Hemp fibres: extraction and applications. Rev. Inno. Textil, 8, 22. CONFERENCE PRESENTATIONS 1. Paul R., et al. Multifunctional Textiles by Plasma Treatments and Nanofinishing. The Fourth International R&D Project Proposals Brokerage Event in Textiles and Clothing, Bursa, Turkey, 2-3 February Paul R. et al. Bast Fibre based Multifunctional Home Textile Products The Fourth International R&D Project Proposals Brokerage Event in Textiles and Clothing, Bursa, Turkey, 2-3 February García A., et al. Thermal Stress Sensoring System in Personal Protection Equipments for Emergency Situations. SMARTEX-2011: 1st World Textiles Conference, Kafrelsheikh University, Egypt, November Crespo L. et al. Synthesis and Characterization of Antibacterial Chitosan Microspheres for Textile Applications. XIX International Conference on Bioencapsulation, Amboise, France, 5-8 October Esteve H. et al. New Horizons in Textile Research. 11th Narrow Fabric Conference (Jakob Müller), Barcelona, 21 September Paul R., et al. Conductive Fabrics using Carbon Nanotubes. 50th Dornbirn Man-made Fibers Congress, Dornbirn, Austria, September Crespo L., et al. Chitosan Microspheres for Antibacterial Finishes. AUTEX 2011 World Textile Conference, Mulhouse, France, 8-10 June Paul R., et al. FIBNATEX PROJECT: Innovative Textiles from Hemp Fibres. 37 Simposio de la AEQCT: La Industria Textil en los Próximos Años, Barcelona, Spain, 6-7 April Paul R. FIBNATEX PROJECT: Benefits of Industrial Hemp. AGRIGANGA: II Feria Agrícola, Ganadera, Agroalimentaria, Nuevas Tecnologías y del Medioambiente de Láchar, Láchar, Spain, 26 March Surribas, A., et al. Biotechnological Cotton Processing. 7th International Conference on Polymer and Textile Biotechnology, Milan, Italy, 2-4 March Brouta M., et al. Advanced Textile Coatings based on Sol-Gel and Plasma Technologies. International Conference on Textile Coating and Laminating 2010 (TCL 2010), Cannes, France, 4-5 November Paul R., et al. Study of the Interaction of Commercial Surfactants on New Textile Products. 49th Dornbirn Man-made Fibers Congress, Dornbirn, Austria, September PATENTS 1. WO 2011/ A2. C. Hijosa, A. Ribé Gallart, J. Jiménez Romero, R. Paul, M. Brouta-Agnésa. 2. WO 2011/ A2. D. Van de Vyver, F. Godefroidt, D. Luyckx, L. Chaboche, K. Eufinger, R. Paul, M. Vanneste, M. Van Parys, X. Decant, H. Esteve. 3. ES P A1. J. Mota, H. Esteve, L. Bautista, D. Amantia, R. Paul, M. Morón, M. de la Varga, M. Brouta-Agnésa. 4. ES P D. Amantia, L. Aubouy, A. Ribé, J. Jiménez Romero. 5. ES P L. Aubouy, J. Jiménez Romero, J. Sáez Zamora, A. Ribé Gallart 6. ES P L. Aubouy, J. Sáez Zamora, J. Jiménez Romero, J. Suarez Jiménez. 7. ES P L. Aubouy, J. Sáez Zamora, J. Jiménez Romero, J. Suarez Jiménez. 8. ES P L. Aubouy, J. Sáez Zamora, J. Jiménez Romero, J. Suarez Jiménez. 33

34 SMART SYSTEMS Competency Compendium Eng. José SAEZ Coordinator of Smart Systems Division Main research fields: Electronics and Smart Systems. Equipments: Rapid PCB Prototyping Multimeters and Oscilloscope Laboratory Function Generator and Power supplies Digital printing Inkjet Screen Printer Equipment Thermo sealer Textile integration workshop Digital Data logger Humidity and temperature probes Thermo graphic camera Mechanical and electronic Workshop Electronic design and simulation software µ-processor development set Zig Bee development kit. Potentiostat/Galvanostat Calorimeter. Other Available Facilities: Climate Simulation Chambers Rapid Plastic Piece Prototyping Sun Radiation Simulation Chambers Textiles testing equipments (Dynamometer, abrasion, pressure test equipments, pilling test equipments, Uster regularimeter, mobile colorimeter, refractory furnaces, flame retardant tests ) Point and warp looms Frame stamping equipment SPECIFIC RESEARCH INTERESTS Thermoelectricity: o Specific applications design and prototyping. o Custom made thermoelectric modules development. o Thermal requirements calculation and simulation. Medical devices: o Custom made portable devices. o Bio-parameter monitoring devices. 34

35 o Bio-sensors. Energy harvesting: o Renewable energy sources. o Self-powered devices. o Energy harvesting modules design and development. Smart Systems: o Sensors and actuators development and integration. o Wireless communications. o Firmware development. Energy Storage o Li-ion Batteries. o Supercapacitors. E-Textiles: o Electronic integration in Smart Textiles. o Electronics on flexible substrates. o Flexible and stretchable conductive materials. Prototype development: o Renewable energies applications. o Electronics applied to high performance sports. o New commercial products. o Small production series custom-made devices. MOST RELEVANT PROJECTS 1. Microflex: microfabrication technologies for flexible substrates. NMP , CP-IP Bio-ICN: Biosensor for fast detection of breast cancer. Industrial Funding. 3. VACMON: biosensor for fast vaccine monitoring. PID MAS: Mobile Ambient Assisted Living ENIAC Joint Undertaking. Grant Agreement Nº CSSL: Consumerizing Solid State Lighting ENIAC Joint Undertaking. Grant Agreement Nº VERDE: Research and knowledge generation about the manufucture and integration of the full electric vehicle in Spain Ministry of Science and Innovation, National Strategic Consortium Project in Technical Research (CENIT), END: Models, solutions, methods and tools for energy aware design ENIAC Joint Undertaking. Grant Agreement Nº ASTUTE: Pro-active decision support for data intensive environments. ARTEMIS Joint Undertaking. Grant Agreement Nº NANOTEG: Nanostructured Thermoelectric Systems for Green Transport & Energy Efficient Applications Eniac Joint Undertaking. Grant Agreement Nº E2SG: Electronic and communication systems for the integration of renewable energy sources into Smart Grid ENIAC Joint Undertaking. ENIAC-ED-52 v DEMANES: Design, Monitoring and Operation of Adaptive Networked Embedded Systems. ARTEMIS Joint Undertaking. Grant Agreement Nº ITACA: Research in technologies water treatment, reutilization and control to allow future sustainability in residual water management. 35

36 PUBLICATIONS 1. Javier Jimenez, José Saez, Laurent Aubouy Smart Playpen, TUT, 2007, 63, J. Jiménez, L. Aubouy, J. Sáez, L.Bautista, A.Briz, M. DelaVarga y J. Parra A general view on the future of textile sector (1), Revista de la Industria textil, 2007,447, J. Jiménez, L. Aubouy, J. Sáez, L.Bautista, A. riz, M. DelaVarga y J. Parra A general view on the future of textile sector (2), Revista de la Industria textil, 2007, 448, A. Detrell, J. Jiménez, L. Aubouy, J. Sáez, L. Bautista, A. Briz, M. DelaVarga y J. Parra, The textile recovers life, Diffusion Sport Magazine, 2007, 112, D. Gutierrez, L. Aubouy, C. Largeot, M. Faccini, J. Suarez, J. Saez. Ultracapacitors: Adding power to full and hybrid electric vehicles. PATENTS 1. ES P L. Aubouy, J. Sáez Zamora, J. Jiménez Romero, J. Suarez Jiménez 2. ES P L. Aubouy, J. Sáez Zamora, J. Jiménez Romero, J. Suarez Jiménez 3. ES P L. Aubouy, J. Sáez Zamora, J. Jiménez Romero, J. Suarez Jiménez 4. ES P A. M. Jiménez Maroto, L. Aubouy, J. Sáez Zamora, J. Jiménez Romero 5. ES P L. Aubouy, J. Jiménez Romero, J. Sáez Zamora 6. ES P L. Aubouy, J. Jiménez Romero, J. Sáez Zamora 7. ES P L. Aubouy, J. Jiménez Romero, J. Sáez Zamora 8. ES P L. Aubouy, J. Jiménez Romero, J. Sáez Zamora 9. ES P L. Aubouy, J. Jiménez Romero, J. Sáez Zamora 10. ES P J.A. Sáez Zamora, J. Suarez Jiménez, F. Agustín Mora, F.A. París Casadelles, D. Tutusaus Martínez. 36

37 NEW PRODUCTION PROCESSES Competency Compendium Eng. Magí GALINDO ANGUERA Coordinator of the New Production Processes Division Main research fields: Product and Process Design and Development, Advanced manufacturing technologies: Additive manufacturing, Robotics and Artificial Vision. Equipments: CAID, CAD and CAM facilities equipped with: o Catia V5 R17 and Solidworks 2010 o Wacom Cintiq 21UX tablet with Photoshop CS3 o Dimension, Additive layer manufacturing system from Stratassys o Reverse Engineering software: Polyworks Modeller, Nurbs and Inspector o Structured light 3D scanner Sidio Pro and digitizer software Triple Software CAE : Ansys Workbench Mechanical /Thermal Production facilities equipped with: Coesfeld, CNC milling machine + Galaad Integrated CAD/CAM/CNC software Injection Molding Machine Polymer Extrusion Machine Workshop equipped with auxiliary machinery. Analysis and Characterization facilities: Mechanical Characterization Laboratory SPECIFIC RESEARCH INTERESTS Product and Process Design and Manufacturing: Creation of new products and redesign of existing ones using transformation design techniques. Focused on clear understanding of roles and expected behaviour of products, designing new products or revised versions of existing products and identifying market and product applications. Planning of production processes based on general characteristics of the product, in the material, surface finishes, tolerances, production tools, machines, assembly and speed or production rate, etc. Software CAD/CAE/CAM and Reverse Engineering: The engineering design supported by CAD / CAE techniques allows optimization of the product before manufacturing assisted by CAM tools, the management of rapid product development and the advance of the start of production. Reverse Engineering (RE) allows the generation of surface models using 3D scanning techniques and thus allows the production of both parts and tools. The aesthetic and ergonomic products demanded by the market need for ever more complex shapes that CAD systems can not solve for themselves. The reverse engineering provides solutions to the request of constantly reducing development time and the need to form increasingly complex new products. Additive Manufacturing Technologies and their industrial applications: These technologies are used to directly construct three-dimensional models and end-use products from electronic data. An additive manufacturing system use CAD data to build parts layer by layer in very thin cross-sections. Our focus is 37

38 placed on the technologies software, hardware, materials and processes- that help conceive, test, improve and manufacture new products to bring them to market faster and most cost effectively. Machining and Material Removal, Molds, Tools and Dies Design and Manufacturing: As part of the overall process of product development from conceptual stage to its industrialization, we pay particular attention to the more conventional systems of both production and processing of polymeric and metallic materials. CNC machining systems as a set of core technologies of production; design and construction of injection molding or die casting; designing and building of special tools and testing tools are part of our research interests too. Automated Manufacturing and Assembly, Computer Integrated Manufacturing and Robotics, Artificial Vision Systems and Digital Image Processing: Robotics sensors and intelligent grippers, Industrial control systems integration, Testing and measurement automation, New robotic functionalities and application areas Identification Systems and Part Traceability by means of RFID or Artificial Vision, Smart navigation systems. MOST RELEVANT PROJECTS 1. Smart System: New bumper with active schock absorber. RD SAM: Safety drug delivery. Cooperative Nucleus R+D+i RD Lightmotorcycle: New materials and designs to obtain lighter motorcycles. Cooperative Nucleus R+D+i, RD Argos. New robot platform with autonomous navigation and smart surveillance system.cooperative Nucleus R+D+I, RD Nocosot project aims to design and develop a new underground container for collecting waste, based on an innovative concept. IEDES Defecto Zero aims to eliminate manufacturing defects through the design, development, implementation and validation of a flexible dimensional inspection system on the vehicle production line to ensure production quality in real time and correct the process in a flexible manufacturing system by an intelligent defects assessment. IDI Target project goal is to research and develop smart and environmentally sustainable new technologies for the generation of structures in composite materials. Research focuses on materials, both existing and new, and processes to eliminate the use of large autoclaves, whilst providing the necessary knowledge bases for the development of new concepts in machinery and automation for the mentioned processes. CEN D LightTrans: Large scale manufacturing technology for high-performance lightweight 3D multifunctional composites. The goal of the project is to create a highly flexible manufacturing chain for low cost production of integral large scale 3D TRPC parts, based on innovative approaches for the individual processes and its integration in the complete supply chain. FP7-NMP Grain. The main objectives of GRAIN are to identify and assess the future development of large scale simulation methods and tools needed for greener technologies to deeper understand and minimize the effects of aircraft/engine design on climate and noise impact, reaching the Vision 2020 environmental goals. FP7-TRANSPORT Restoration. Research and innovation for advanced multifunctional ceramic materials. Resorbable Ceramic Biocomposites for Orthopaedic and Maxillofacial Applications. New Production Processes team leads the research and development of finite element and dissolution/bone remodelling models to predict the mechanical performance of the devices over time. FP7-NMP

39 PUBLICATIONS Oral presentations and Congress contributions 1. Current and available technologies of Rapid Prototyping and Rapid Tooling. Industrial examples. NEW TECHNOLOGIES IN RAPID PROTOTYPING. Parque tecn. de Barcelona, Barcelona (March 25 th, 2004). 2. Advances and trends in Rapid Prototyping y Rapid Manufacturing. FORUM MAQUITEC Barcelona (October 21 st, 2004). 3. Preliminary point and requirements for the use of SFF systems. I TECHNICAL FORUM OF THE RP & DM IN THE INDUSTRIAL FOUNDRY in ETR, Ripoll (November 24 th, 2005). 4. RM the beginning of a new industrial revolution and a source of new business opportunities. II RM TECHNICAL FORUM. Girona (December 14 th, 2006). 5. RM, new business opportunities for Industrial Designers. Conference new opportunities of business with the Rapid Manufacturing. ADI-FAD, Barcelona (June 17 th, 2008). 6. RM state of the art, processes, materials and applications. I One Day Seminar on RM: Manufacturing Reinvented. Institut Químic de Sarrià, Barcelona (November 11 th, 2008). 7. "Technologies of advanced manufacture and its application to the medical technologies. RM Forum. 2nd Edition. Manufacturing reinvented for medical and biomedical applications. Institut Químic de Sarrià, Barcelona (June 29 th, 2009). 8. Unleashing AM through software solutions AM Forum 3 rd edition. the third workshop on Additive Manufacturing held at Diseny HUB Barcelona, June 28 th, Seminars and workshops 1. Prototyping in the product development". 4 hr Session belonging to the Master in Production and Engineering Integrated for Computer and at the Postgraduate Course in Development of Engineering of Product (ICT / UPC). BLOC C: VERIFICATION AND REDESIGN OF PRODUCTS. Technologies to obtain prototypes. Traditional techniques. Rapid Prototyping. The prototyping in the projects of product engineering. Exhibition of real cases. Coordinated course for Felip Fenollosa (Director of operations of the Centre CIM. Place: CIM Center, C. Llorens i Artigas 1-2, Barcelona. 2. Rapid prototyping in the Design of Product". 4 hr session belonging to the Technical Postgraduate Course CAD /CAM (ICT / UPC). Rapid Prototyping of product. Linking between CAD and RP. Technologies for the fast manufacture of prototypes. Coordinated course for Felip Fenollosa (Director of operations of the Centre CIM. Place: CIM Center, C. Llorens i Artigas 1-2, Barcelona. 3. Technology of materials and Technologies of production in the area of the additive manufacture." 8 hr sessions belonging to the Fourth and Fifth Course of Industrial Engineering. Technologies and materials for the direct manufacture or Rapid Manufacturing. Coordinated course for Dr. Salvador Borrós and Dr. Guillermo Reyes of Institut Químic de Sarrià. (IQS) Via Augusta 390, Barcelona. 4. Participation as speaker in different formation seminars of the technologies of RP/RT and RM in companies like Roca Radiadors (Gavà), SEAT and EDAG (Martorell), Mercedes Benz (Vitoria), Ficocables and Sogefi Filtration (Rubí), Valeo Climatització, Ficomirrors and Zanini (Mollet), IMC Toys (Terrassa), HUF (Burgo de Osma-Soria), ESPA Bombas Eléctricas (Banyoles) etc., and in seminars organized by DRL and PROTOMOLD in Argentona, Cabrils, Vigo... oriented to companies of the automotive sector and of the industry of the transformation of plastic in general. PRIZES 1. B-Here, honorable mention second prize- of the Sustainability and Architecture Association (ASA) design contest "KBXXI: Barcelona s 21 st century Kamishibai." PATENTS Spain Patent num , for "DISPOSITIVO PARA APLICAR ADHESIVO DESDE UN VIAL O AMPOLLA DE PAREDES DEFORMABLES Y KIT DOSIFICADOR DE ADHESIVO QUE INCLUYE DICHO DISPOSITIVO APLICADOR" 39

40 ENVIRONMENT Competency Compendium Dr. Julia GARCÍA-MONTAÑO Coordinator of Environment Division Equipments: Total Organic Carbon (TOC) analyzer Chemical Oxygen Demand (COD) and Biochemical Oxygen Demand (BOD) equipment N kjeldahl Adsorbable Organic Halogens (AOX) analyzer Microtox instrument (acute toxicity) GC-MS, LC-MS, HPLC-PDA, Ion Chromatograph ICP-MS Respirometer for biodegradability assessment Equipment for the microbiological analysis of water Advanced Oxidation Processes (AOPs) reactors and photo-reactors Electrocoagulation and Electrooxidation and electrowinning cells GE Osmonics filtration equipment (flat membranes) N 2 Filter (Millipore) MMS laboratory filtration membrane equipment (spiral, tubular and hollow fiber membranes) MMS pilot filtration membrane equipment (spiral, tubular and hollow fiber membranes) Ceramic membrane filtration equipment Laboratory equipment of aerobic biological treatment Aerobic biological treatment pilot plant Physic-chemical treatment pilot plant Anaerobic biological treatment pilot plant MBR treatment pilot plant Filter press equipment Jar-test Portable Turbidimeter Refractometer SDI equipment Portable MultiParametric probe Nasal Ranger field olfactometer Portable Single Gas Detector SPME fibers Vertex uptake pump Thermal desorber Dispersion Software SimaPro LCA software 40

41 SPECIFIC RESEARCH INTERESTS Water treatment: Alternative water treatment technologies: Electrochemical processes (Electrocoagulation, Electrooxidation, Electrowinning and Electrodyalisis ), Nanotechnology (nanoparticles and nanofibres for water filtration), Biotechnology (enzymes), Microalgae; Advanced Oxidation Processes (Fenton type reactions, heterogeneous photocatalysis, Ozone); Membrane processes (Reverse Osmosis, Microfiltration, Ultrafiltration, Nanofiltration), functionalised membranes for selective filtration; Biological Treatments (aerobic, anaerobic), Microbial Fuel Cells, Wetlands, Biosorption; combined treatments; high added value products recovery and valorisation. Minimisation of water consumption: optimisation and design of new productive processes, generation of new water resources, water reuse. Alternative energy generation: energy production from wastewater, energy savings for water recovery. Emergent contaminants detection and quantification: dyes, drugs, nanoparticles,... Waste minimisation and waste valorisation: optimisation and design of new productive processes, high-added value products isolation and valorisation. Energy from biomass residues and wastes: feasibility analysis of biomass supply (extracting forest biomass, biomass residues, energy crops, microalgae, sewage sludge, natural drying studies, transportation); physical, chemical and energy valorisation of biomass (feasibility analysis: pelleting/briquetting/chipping, combustion, gasification and pyrolysis technologies, CHP, power generation, composting biological treatments, anaerobic digestion). Air Quality ODOURS: indoor and outdoor COV s and odours studies. Chemical and sensor methods, photocatalytic treatment of contaminated atmospheres. Pilot plants design and construction Life Cycle Assessment (LCA): environmental assessment of a particular product or process, development of specific methodologies for industrial sectors (tailored assessments). Ecoproducts and Ecoprocesses Sediment characterization (surface water) and hydrogeological studies MOST RELEVANT PROJECTS 1. ITACA (Research on Technologies for treatment, reuse and monitoring for future sustainability of water treatment) INNPRONTA IPT URWASTECH (Innovative Urban Waste Treatment: a sustainable approach using hydrodynamic and biological technologies) European Project: LIFE I-004 LIFE+. 3. ELVISUSTECH (End Life Vehicles: Innovative and Sustainable Technology for Achieving European Directive Targets) European Project: LIFE I-017 LIFE+. 4. SENSOSEP (New technologies in sensors and ejectors to improve the solid waste separation) - Regional Project: NUCLI ACC1O 2009, RD REPHATER (Electrochemical water treatment pilot plant in the dairy industry with phosphate recovery). European Project: CIP-EIP-Eco-Innovation-2008, ECOMETRE (Ecological Metal Recovery). European Project: CIP-EIP-Eco-Innovation-2008, SEILA: New Technologies for an efficient, ecologic and intelligent washing system for the future textiles, CENIT CEN Viability study of the reuse of water coming from WWTP in the Vallès Occidental region for industrial uses. Regional Project: AGAUR Ref: 2008ACOM

42 9. Treatment and reuse of textile wastewater by means of Advanced Oxidation Processes. National project: Ministerio de Industria, Turismo y Comercio; LIA Desarrollo experimental Ref: DEX Investigation of alternative technologies for industrial wastewater treatment. Nacional Project: Ministerio de Industria, Turismo y Comercio; LIA CT Ref: DEX Treatment and waste valorization from a pharmaceutical company. Industrial Project Reutilization study of water coming from the WWTP in Terrassa for industrial uses. Industrial project with the Catalan Water Agency (ACA). Ref: CTN BIOLEC: New advanced electrochemical technologies for the treatment of wastewater coming from biodiesel industry. Autonomic project: VALTEC ACC1O VALTEC Reclamation and reuse of treated wastewater from a WWTP in the Vallès Occidental region for industrial uses. Regional Project: AGAUR Ref: 2009ACOM R-FISH, LIFE+, January LIFE07 ENV/E/ Research and development of new technologies for wastewater treatment in the textile industry. Postdoctoral project 2007BP-B PUBLICATIONS 1. Jose Blanco, Francesc Torrades, Mertitxell de la Varga, Julia García-Montaño. Fenton and biological Fenton coupled processes for textile wastewater treatment and reuse. Desalination 286 (2012) Conference: REPHATER: Elecrochemical water treatment pilot plant in a dairy industry with phosphate recovery, CHEMPOR 2011, Lisboa, September David Galí, Julia García-Montaño, Meritxell de la Varga, Electrochemical Advanced Processes to biodiesel wastewater treatment (BIOLEC), Chempor 2011, Lisboa, September 2011, poster. 4. Julia García Montaño, Carlos Pérez Wait and Meritxell de la Varga, ECOMETRE: Ecologival metal recycling. 12th Mediterranean Congress of Chemical Engineering, Barcelona, November 2011, poster. 5. José Blanco, Francesc Torrades, David Galí, Julia García-Montaño, MdelaVarga, Use of textile wastewater for dyeing processes after photo-fenton and coupled biological-photo-fenton treatment. 12th Mediterranean Congress of Chemical Engineering, Barcelona, November 2011, poster. 6. Conference: Remediation of textile wastewaters by means of Fenton and biological-fenton coupled processes. 6 th European Meeting on Chemical Industry and Environment, May 2010, Mechelen, Belgium, 7. Jose Blanco, Francesc Torrades, Julia García Montaño, María. Navarro, David Galí, Meritxell de la Varga. Use of photo-fenton reactions for textile wastewater treatment and reuse, 6 th European Meeting on Chemical Industry and Environment, May 2010, Mechelen, Belgium, poster. 8. Conference: Electrochemical water treatment pilot plant in the dairy industry with phosphate recovery, SMAGUA 2010, Zaragoza, 4 March 2010, 9. Conference: Reutilisation study of water from the Terrassa municipal Waste Water Treatment Plant for industrial applications, Terrassa, Barcelona, 3 March Conference: Viability study of the industrial reuse of water in Terrassa, Ecosessions, Environment Sessions (Ecocity & Industry). Barcelona Fair, L hospitalet de Llobregat. 28 May Maria N. Abellan, David Galí, Mertixell DelaVarga, Julia García-Montaño, Miren Blanco, Amaia Martínez, Arrate Marcaide. Regeneration of paper mill wastewater with Fenton and photo-fenton processes. INNOVAMED CONFERENCE, October 2009, Girona, poster. 12. José Blanco, Maria N. Abellan, David Galí, Meritxell DelaVarga, Julia García-Montaño, Francesc Torrades. Fenton and biological-fenton coupled processes for textile wastewater treatment and reuse. INNOVAMED CONFERENCE, October 2009, Girona, poster. 42

43 RENEWABLE ENERGIES Competency Compendium Dr. David GUTIÉRREZ-TAUSTE Manager Renewable Energies Division, R&D department Equipments: Other Facilities: Sun simulator AM1.5G (AAA class 2x 2 cm 2, B class up to 2 m 2 of irradiated area) UV light sources Metal halide light sources J-V characterisation I-V supply sources UV-Vis-NIR spectrometer Pyranometer and calibrated c-si solar cells Data acquisition equipment Battery of different ageing chambers (climatic, UV-climatic, Xenotest, saline, etc.) AutoLAB potentiostat / galvanostat Multichannel VMP3 potentiostat / galvanostat Glove box Hydrothermal reactors (up to 20 bar, 350ºC), coupled to micro-gas chromatograph CAD (CATIA), FEA tools, rapid prototyping Ink/paste formulations and deposition techniques (ink-jet printing, screen printing, spraying, doctor bladding, electrospinning) Chemical laboratory Physicochemical characterisation (ATR-FTIR, ICP-MS, HPLC, UV-Vis spectrophotometer, Differential Scanning Calorimetry, Total Organic Carbon analyser, ionic chromatography, Karl Fischer, contact angle, optical microscopy, conductivity, biodegradability, toxicity, perfilometer, etc.) SPECIFIC RESEARCH INTERESTS Design of innovative solar concentrators and tracking systems for photovoltaics. Novel nanoarchitectures and manufacturing processes for organic/hybrid photovoltaics (Organic/Dye Sensitized Solar Cells). Seebeck/Peltier effects in renewable energy production (thermoelectricity). Combined antireflection-cooling lenses for photovoltaics. Innovative refrigeration concepts for photovoltaics. Novel luminescent solar concentrators based on photoluminescence, down-shifting and up-conversion phenomena for photovoltaics. Clean hydrogen fuel-carrier production and Fuel Cell technologies 43

44 Ionic liquids as novel media for renewable energy production. Novel forms of CO 2 capture and valorization. PCM (Phase Change Materials) for energy storage. Innovative refrigeration concepts based on thermoelectricity. Integration of renewable energy power sources in specific applications. Microbial Fuel Cells Electrochemical Double Layer Supercapacitors Li-ion and Li-air batteries Examples of experiments: Improving solar-to-electrical energy conversion efficiency of classical photovoltaics by means of backcoupling cooling systems based on Phase Change Materials or Peltier cells. Performance studies carried out upon simulated sunlight at different intensities. Performance studies of home-made solar concentrators, tacking systems and luminescent solar concentrators under simulated sunlight at different intensities. Synthesis and characterization of materials for energy applications e.g. C-based electrodes for supercapacitors or highly hydrophobic electrolytes for lithium battery technologies. Design and construction of home-made prototypes for different applications in photovoltaics, thermoelectricity or energy storage. Design, development and optimization of novel concepts of PV modules, supercapacitors, Li-ion or Liair energy storage technologies. CO 2 capture and valorization in novel media (e.g. low-cost ionic liquids). MOST RELEVANT PROJECTS 1. Improving efficiency of photovoltaic systems, co-financed By Caixa Terrassa. 2. EPHOCELL: Smart Light Collecting system for the efficiency enhancement of solar cells, NMP and ENERGY , FP7. Grant ENERTEX: Energy harvesting from human body heat using thermoelectric modules. FIT SUPERCAP: Research and development of new supercapacitors based on double layer and pseudocapacitative electrochemical effects. Co-financed by ACC1O and FEDER (RD ). 5. LIQUION: Research on ionic liquid technologies for industrial applications. Co-financed by CDTI. CEN Capture and valorization of CO 2. Co-financed by Obra social Unnim Caixa Terrassa. 7. PHOTOFUTURE: Study and realization of new generation luminescent solar concentrators, Marie Curie FP7 programme, grant agreement (host institution) 8. NANOTHERM: Tailoring electronic and phononic properties of nanomaterials: towards ideal thermoelectricity, Consolider-Ingenio NEXTEC: Themoelectric energy converters based on nanotechnology. NMP , grant agreement ITACA: Development of technologies for the treatment, reutilization and control of future sustainable water treatment. Innpronta

45 PUBLICATIONS 1. D. Gutiérrez-Tauste et. al. New low-temperature preparation method of the TiO 2 porous photoelectrode for dye-sensitized solar cells using UV irradiation. Journal of Photochemistry and Photobiology A: Chemistry 175 (2005) L. Aubouy et. al. Europium: Nature, Luminescence and Applications, Anales de la Real Sociedad Española de Química 102 (2006) Anales de la Real Sociedad Española de Química 102 (2006) D. Gutiérrez-Tauste et. al. Hexafluorotitanate salts containing organic cations: use as a reaction medium and precursor to the synthesis of titanium dioxide. Chemical Communications (2007) D. Gutiérrez-Tauste et. al. Low-temperature preparation route for nanocrystalline TiO 2 in multigram scale using R 2 TiF 6 (R=BetH +, Cho + ) ionic liquid like precursor solutions: Application in Dye-Sensitized Solar Cells, HOPV conference D. Gutiérrez-Tauste et. al. EPHOCELL project: smart light collecting system for the efficiency enhancement of solar cells, HOPV conference D. Gutiérrez-Tauste et. al. Solar cell efficiency enhancement through down-shifting and up-converting layers in the Ephocell project, EUPVSEC conference D. Gutiérrez-Tauste, C. Largeot, J.A. Sáez, D. Amantia, M. Faccini: Electrochemical Double Layer Capacitors: technology overview and reference materials, IRES conference D. Gutiérrez-Tauste, J Skinner, M. della Pirriera, C. Largeot, I. Cascallana-Matías: Developing and testing low-cost ionic liquids for CO 2 capture, XI International Conference on Carbon Dioxide Utilization D. Gutiérrez-Tauste, M. della Pirriera et.al.: Polymer gels as media for down-shifting and up-conversion, Advances in polymer gel material and related technologies M. Tonezzer, D. Gutiérrez-Tauste, M. della Pirriera et.al.: PHOTOFUTURE Project, EMRS D. Gutiérrez-Tauste, C. Largeot, J. A. Saez, J. Suarez, M. Faccini, A. Almarza: Supercapacitors development, Advanced Automotive Battery Conference A. Almarza, M. Faccini, D. Amantia, C. Largeot, D. Gutiérrez-Tauste, J. A. Sáez: Development of electrospun nanofibers as lithium-ion batteries electrodes, Advanced Automotive Battery Conference D. Gutiérrez-Tauste, C. Aucher, C. Largeot, J.A. Saez, D. Amantia, M. Faccini: Development of industrial supercapacitors with novel materials, IRES M. Martin-González, A. Almarza, D. Amantia, S. Vázquez-Campos: Thermal diffusivity measurements of polyaniline and polyaniline/nanoclay composites, Spanish-Japanese workshop on Nanotechnology and New Materials to face Environmental Challenges M. Tonezzer, D. Gutiérrez-Tauste, M. della Pirriera et.al.: PHOTOFUTURE Project: preliminary results on novel luminescent solar concentrator, PVSEC M. Tonezzer, D. Gutiérrez-Tauste, M. della Pirriera et.al.: Novel Rare Earth based luminiscent solar concentrators, TICME D. Gutiérrez R&D projects on materials for renewable energies at Leitat, TICME M. Tonezzer, D. Gutiérrez-Tauste, M. della Pirriera: Novel Luminiscent Solar Concentrators, INFN-LNL report, 99, PATENTS 1. ES. P L. Aubouy et al. 45

46 LEITAT TECHNOLOGICAL CENTER IS MEMBER OF ACCEL - Agrupación para la Consecución de un Cielo Europeo Limpio AEI TExtil Agrupació d Empreses Innovadores Tèxtils AELAF Asociación Española de Laboratorios de Fuego AENEAS Aliança BioNanoMed - Association Catalunya for European NanoElectronics Activities APPICE - Asociación Española de Pilas de Combustible ARTEMIS ASEBIO Industry Asociación Association Española de Bioempresas ASERM Asociación Española de Rapid Manufacturing Asociación de Técnicos de la Industria Textil ASTEC - Associació Catalana de Tecnologia Biocat - Clúster biotecnológico y biomédico de Catalunya CataloniaBio Associació Catalana d Empreses Biotecnològiques Club EMAS - Associació d'empreses registrades EMAS a Catalunya Cluster Marítimo Español E2BA EuroLab Energy España Efficient Building Association E-GOLF European FEDIT - Centros - Asociación Textile Tecnológicos Collectivities Europea de de Association España Laboratorios de Fuego FELAB Asociación de entidades de Ensayo, Calibración y Análisis EFFRA - European Factories of the Future Research Association Genoma España Fundación para la investigación genómica aplicada Enterprise Europe Network Groupe Grup Connect-EU Europeén / d échange Automoción d expériences sostenible Sur la Direction de la Recherche Textile ERA-Net Grup Connect-EU ICT-AGRI / Catálisis (LEITAT Sostenible participa como observador dentro de este programa europeo) Grup Connect-EU / Energía EU Grup PV Connect-EU Clusters / Factorías del futuro EURACHEM Grup Connect-EU Network / Materiales of Organitzations for Analytical Chemistry in Europe Grup Connect-EU / Nanobio + Nanomed Grup Connect-EU / Water.cat IDESCAT - Cluster Català de l'esport NanoImpactNet Oficina d Acreditació d Entitats Col laboradores Nanosafety Oncocat Red Cluster Catalana de Oncología R+D+I REDMA Project Red Euro-Action de Laboratorios Group y Entidades Association de Inspección Medioambiental SECARTYS - Asociación Española para la Internacionalización de las Empresas de Electrónica, Informática y Telecomunicaciones STA - Sociedad de Técnicos de Automoción TECNIO - Expertos en investigación aplicada y transferencia tecnológica de Catalunya EUROPEAN TECHNOLOGY PLATFORMS European Technology Platform on Smart Systems Integration (EPoSS) European Platform for Sports and Innovation (ÉPSI-eu) European Technology Platform on Industrial Safety (ETPIS) European Technology Platform on Advanced Engineering Materials and Technologies (EuMat) 46

47 European Technology Platform for the future of textiles and clothing (NO participamos directamente sino a través del Consejo Intertextil Español) (EURATEX) In Vitro Testing Industria Platform (IVTIP) European initiative for sustainable development by Nanotechnologies (NANOfutures) Renewable Heating & Cooling European Technology Platform (RHC-ETP) Rapid Manufacturing Platform (RM-Platform) European Technology Platform for Sustainable Chemistry (Suschem) Water Supply and Sanitation Technology Platform (WSSTP) SPANISH TECHNOLOGY PLATFORMS Plataforma Tecnológica Española de la Biomasa (BioPlat) Plataforma Tecnológica Española de tecnologías para la Salud, El Bienestar y la Cohesión Social (evia) Food for Life Spain (FFL-Spain) Plataforma Tecnológica Española de Nanoelectrónica e Integración de Sistemas Inteligentes (Genesis Red) Plataforma Tecnológica Española de la Industria del Deporte (Inesport) Plataforma Tecnológica Española de logística Integral (Logistop) Plataforma Tecnológica Española de investigación en el ámbito de la fabricación (Manufuture-E) Plataforma Española de Nanomedicina (Nanomed) Plataforma Tecnológica Tecnologica Española de Seguridad Envase y Embalaje Industrial (PACKNET) (PESI) Plataforma Tecnológica Española del Agua (PTEA) Plataforma Tecnológica Española de la Construcción (PTEC) Plataforma Tecnológica Española de Hidrógeno y Pilas de Combustible (PTE-HPC) Plataforma Tecnológica Marítima (PTEM) Plataforma Tecnológica Española de la Pesca y la Acuicultura (PTEPA) Plataforma Tecnológica del Hogar Digital (PTHD) Plataforma Tecnológica para la Protección de la Costa y del Medio Marino (PT- PROTECMA) Plataforma Tecnológica Española para el Sector de Componentes de Automoción (SERtec) Plataforma Solar CONCENTRA (SOLAR CONCENTRA) Plataforma Tecnológica Española de Química Sostenible (Suschem-E) Plataforma de Mercados Biotecnológicos Plataforma Tecnológica Textil Española 47

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