evaluation of cancer hazards Robert A Baan PhD The IARC MONOGRAPHS International Agency for Research on Cancer Lyon, France
|
|
- Lawrence Haynes
- 8 years ago
- Views:
Transcription
1 Consumption of alcoholic beverages; evaluation of cancer hazards Robert A Baan PhD The IARC MONOGRAPHS International Agency for Research on Cancer Lyon, France
2 The IARC Monographs The IARC Monographs are an authoritative series of scientific reviews that t identify environmental factors that t can increase the risk for human cancer. This cancer-hazard identification is a first step in cancer-risk assessment and cancer prevention Each Monograph includes a critical review by an ad-hoc Working Group of the pertinent scientific literature, and an evaluation of the weight of the evidence that the agent can increase cancer risks to humans
3 The IARC Monographs The WHO encyclopaedia of carcinogens The IARC Monographs evaluate Chemical agents and complex mixtures Occupational exposures Physical agents, biological agents Personal habits and household exposures More than 900 agents have been evaluated 106 are carcinogenic to humans (Group 1) 59 are probably carcinogenic to humans (Group 2A) 248 are possibly carcinogenic to humans (Group 2B) Dr Lorenzo Tomatis ( ) Founder of the IARC Monographs National and international health agencies use the Monographs as a source of scientific information on known or suspected carcinogens and as scientific support for their actions to prevent exposure to these agents
4 The IARC Monographs IARC Monographs classification (default) of agents on the basis of the strength of evidence of carcinogenicity to humans and to experimental animals HUMAN Sufficient Limited Inadequate (or lack of data) ANIMAL Sufficient 1 2A 2B Limited 1 2B 3 Inadequate 1 2B 3 (or lack of data)
5 Alcoholic beverage consumption (world-wide) wide) The WHO identified the consumption of alcoholic beverages as one of the top-10 risks for world-wide burden of disease (Ezzatti et al., 2004). In 2002, more than 1.9 billion adults ( 15 years of age) around the world were estimated to be regular consumers of alcoholic beverages, with an average daily consumption of 13 g of ethanol (about one drink). Over the past 40 years, alcoholic beverage consumption has remained ed stable in most regions of the world, except in the western Pacific region predominantly China where it has increased by about five times.
6 Alcoholic beverage consumption (European Union) Alcohol consumption in 2005 in the population (> 15 yrs) of the European Union: 10.9 L pure ethanol (EU27), varying from 6.6 L (Sweden) to 14.8 L (Czech Republic) Harmful and hazardous alcohol consumption is the third largest risk factor for ill health in the EU, causing 195,000 deaths each year and accounting for 12% of male and 2% of female premature mortality Young gpeople p are at risk, as over 10% of female mortality and around 25% of male mortality in the yrs age group is related to hazardous alcohol consumption [From: Alcohol in Europe - A public health perspective, P Anderson & B Baumberg, Institute of Alcohol Studies, UK 2006]
7 Alcoholic beverage consumption (European Union) Brussels, , 2006 COM (2006) 625 final COMMUNICATION FROM THE COMMISSION TO THE COUNCIL, THE EUROPEAN PARLIAMENT, THE EUROPEAN ECONOMIC AND SOCIAL COMMITTEE AND THE COMMITTEE OF THE REGIONS An EU strategy to support Member States in reducing alcohol-related harm [this document does not mention cancer at all]
8 Alcoholic beverage consumption (European Union) Data available in 2006 estimated that alcohol consumption- related deaths and ill health effects in the EU included: 10,000 deaths per year due to road-traffic accidents 27,000 deaths as a result of alcohol-related l l accidents 2,000 homicides 10, suicides 45,000 deaths from liver cirrhosis 50, deaths from cancer (11,000 female breast cancer) 17,000 deaths due to neuro-psychiatric conditions Alcohol l is also linked to 200, episodes of depression, accounting for 2.5 million life-years lost to death and disability y( (Disability-Adjusted Life Years). From: First progress report on the Implementation of the EU alcohol strategy (2009)
9 Volume 44 of the IARC Monographs Alcohol drinking (Working Group meeting, October 1987) ) There is sufficient evidence for the carcinogenicity of alcoholic beverages in humans. The occurrence of malignant tumours of the oral cavity, pharynx, larynx, oesophagus and liver is causally related to the consumption of alcoholic beverages. Alcoholic beverages are carcinogenic to humans (Group 1)
10 IARC Monograph volume 44 (1988): cohort studies Oral cavity relative risk with 95% C.I. Norwegian alcoholics 5.0 ( ) Pharynx Norwegian alcoholics 4.4 ( ) Finnish alcoholics 5.7 ( ) Oral cavity/pharynx yp y Norwegian alcoholics 4.8 ( ) Massachusetts alcoholics 3.3 ( ) US Veterans alcoholics 2.2 ( ) Canadian alcoholics 4.2 ( )
11 IARC Monograph volume 44 (1988): case control studies Cancer risk depends on the amount of alcohol consumed Tongue, gum, floor of mouth, buccal mucosa France, 759 men 0-39 g*/day ( ) ( ) > ( ) * intake of pure ethanol (Brugère et al., 1986)
12 IARC Monograph volume 96 (2010) The Working Group reviewed epidemiological studies on the possible association between alcohol consumption and cancer at 27 anatomical sites. Regular alcohol consumption is associated with an increased risk for cancers of the oral cavity, pharynx, larynx, and oesophagus. Daily consumption of around 50 g of alcohol increases the risk for these cancers by two to three times, compared with the risk in nondrinkers.
13 IARC Monograph volume 96 (2010) There is strong evidence that the consumption of alcohol is an independent risk factor for primary liver cancer. Cirrhosis and other liver diseases often occur before the cancer becomes manifest and patients with these disorders generally reduce their alcohol intake. Therefore, the effect of alcohol consumption on the risk for liver cancer is difficult to accurately quantify.
14 IARC Monograph volume 96 (2010) In more than 100 epidemiological studies an increased risk was found for female breast cancer with increasing i alcohol intake. A pooled analysis of 53 studies on more than women with and without breast cancer showed that daily consumption of about 50 g of alcohol is associated with a relative risk of about 1.5 (95% C.I., ), compared with that in non-drinkers. For regular consumption of even 18 g of alcohol per day the relative risk is significantly ifi increased.
15 Moderate alcohol intake and breast-cancer risk (Hamajima et al, 2002)
16 IARC Monograph volume 96 (2010) The association between alcohol consumption and colorectal cancer has been reported in more than 50 prospective and case control studies. Pooled results from eight cohort studies and data from recent meta-analyses provide evidence for an increased relative risk of about 1.4 for colorectal cancer with regular consumption of about 50 g of alcohol per day, compared with that in non-drinkers. This risk seems to be similar for colon cancer and for rectal cancer.
17 IARC Monograph volume 96 (2010) The Working Group confirmed the previous conclusion (Volume 44, 1988) that cancers of the oral cavity, pharynx, larynx, esophagus and liver are causally related to the consumption of alcoholic beverages. In addition, there is sufficient evidence to conclude that breast cancer in women and colorectal l cancer also belong in this list. Overall evaluations: Alcoholic beverages are carcinogenic to humans Ethanol in alcoholic beverages is carcinogenic to humans
18 IARC Monograph volume 100E (in prep.) The metabolism of ethanol (alcohol) involves the action of The metabolism of ethanol (alcohol) involves the action of two enzymes, ADH and ALDH:
19 IARC Monograph volume 100E (in prep.) The variant allele ALDH*2 encodes an inactive subunit of the enzyme ALDH. It is highly prevalent in certain eastern- Asian populations p (28 45%), but rare in other groups. Homozygous carriers of this allele (ALDH*2/*2) are natural abstainers or infrequent drinkers, because the enzyme deficiency would cause a strong facial flushing response, physical discomfort, and severe toxic reactions.
20 IARC Monograph volume 100E (in prep.) In heterozygous carriers (ALDH*1/*2 2, with about 10% residual ALDH activity) these acute adverse effects are less severe, but when they consume alcohol these persons are at high risk for several alcohol-related aerodigestive cancers. For oesophageal cancer the relative risk may be as high as 12 for the ALDH*1/*2 genotype, compared with ALDH*1/*1 carriers, who produce normal ALDH.
21 IARC Monograph volume 100E (in prep.) Overall evaluations (Group 1): Alcoholic beverages are carcinogenic to humans Cancer sites: oral cavity, pharynx, larynx, esophagus, liver, female breast, colorectum Ethanol in alcoholic beverages is carcinogenic to humans Acetaldehyde associated with alcohol drinking is carcinogenic to humans
22 Combined effect of alcohol drinking and smoking Alcohol intake (drinks/week) < >56 Smoking habit (cigarettes/day) Never > Odd s ratios for laryngeal cancer (Talamini et al 2005)
23 The IARC Monographs Acknowledgements The IARC Monographs receive financial support from - U.S. National Cancer Institute (since 1982) - European Commission, DG for Employment, Social Affairs and Equal Opportunities (since 1986) -U.S. National Institute of Environmental Health Sciences (since 1992) - U.S. Environmental Protection Agency (since 2001)
24 The IARC Monographs team Merci à toutes et à tous!
25
Alcohol Quick Facts. New Zealand s drinking patterns. Health impacts. Crime and violence. Drink driving. Social costs
Alcohol Quick Facts New Zealand s drinking patterns 85% of New Zealanders aged 1664 had an alcoholic drink in the past year (Ministry of Health 2009). Three in five (61.6%) past-year drinkers consumed
More informationDefending the Rest Basics on Lung Cancer, Other Cancers and Asbestosis: Review of the B-Read and Pulmonary Function Testing
Defending the Rest Basics on Lung Cancer, Other Cancers and Asbestosis: Review of the B-Read and Pulmonary Function Testing OTHER CANCERS November 2013 Bruce T. Bishop Nancy E. Leary Willcox & Savage 440
More informationAlcohol Quick Facts ALCOHOL FACTS. New Zealand s drinking patterns. Crime and violence. Health impacts. Drink driving.
Alcohol Quick Facts ALCOHOL FACTS New Zealand s drinking patterns The proportion of New Zealanders aged 15 years or more who drank alcohol in the past year dropped from 84% in 2006/07 to 80% in 2011/12
More informationOptimal levels of alcohol consumption for men and women at different ages, and the all-cause mortality attributable to drinking
Optimal levels of alcohol consumption for men and women at different ages, and the all-cause mortality attributable to drinking Ian R. White, Dan R. Altmann and Kiran Nanchahal 1 1. Summary Background
More information2.5 Cancer of the liver
ALCOHOL CONSUMPTION 399 2.4.7 Effect modification The combined effects of smoking and alcoholic beverage consumption on the development of cancer of the oesophagus have been examined in several studies
More informationQ&A on Monographs Volume 116: Coffee, maté, and very hot beverages
Questions about the Monographs 1. What does the IARC Monographs Programme do? The Monographs Programme identifies and evaluates causes of cancer in humans based on the publically available scientific evidence.
More informationAlcohol Units. A brief guide
Alcohol Units A brief guide 1 2 Alcohol Units A brief guide Units of alcohol explained As typical glass sizes have grown and popular drinks have increased in strength over the years, the old rule of thumb
More informationTable 2.2. Cohort studies of consumption of alcoholic beverages and cancer in special populations
North America Canada Canadian 1951 Schmidt & Popham (1981) 1951 70 9 889 alcoholic men, aged 15 years, admitted to the clinical service of the Addiction Research Foundation of Ontario between Death records
More informationADMISSION TO THE PSYCHIATRIC EMERGENCY SERVICES OF PATIENTS WITH ALCOHOL-RELATED MENTAL DISORDER
Bulletin of the Transilvania University of Braşov Series VI: Medical Sciences Vol. 4 (53) No. 2-2011 ADMISSION TO THE PSYCHIATRIC EMERGENCY SERVICES OF PATIENTS WITH ALCOHOL-RELATED MENTAL DISORDER P.
More informationNIOSH Publishes Study of Cancer Among Firefighters Claire Reiss National League of Cities Risk Information Sharing Consortium.
NIOSH Publishes Study of Cancer Among Firefighters Claire Reiss National League of Cities Risk Information Sharing Consortium The National Institute for Occupational Safety and Health has released the
More informationUpdate of the scientific evidence on asbestos and cancer. Kurt Straif, MD MPH PhD. The IARC Monographs
Update of the scientific evidence on asbestos and cancer Kurt Straif, MD MPH PhD International Agency for Research on Cancer Lyon, France World Health Organisation Asturias, 17 March 2011 The IARC Monographs
More informationNo. prev. doc.: 8770/08 SAN 64 Subject: EMPLOYMENT, SOCIAL POLICY, HEALTH AND CONSUMER AFFAIRS COUNCIL MEETING ON 9 AND 10 JUNE 2008
COUNCIL OF THE EUROPEAN UNION Brussels, 22 May 2008 9636/08 SAN 87 NOTE from: Committee of Permanent Representatives (Part 1) to: Council No. prev. doc.: 8770/08 SAN 64 Subject: EMPLOYMENT, SOCIAL POLICY,
More informationQ&A on the carcinogenicity of the consumption of red meat and processed meat
Q. What do you consider as red meat? A. Red meat refers to all mammalian muscle meat, including, beef, veal, pork, lamb, mutton, horse, and goat. Q. What do you consider as processed meat? A. Processed
More informationAlcohol Guidelines Review Report from the Guidelines development group to the UK Chief Medical Officers
Alcohol Guidelines Review Report from the Guidelines development group to the UK Chief Medical Officers January 2016 2 Alcohol Guidelines Review Report from the Guidelines development group to the UK Chief
More informationEconomic recession and alcoholrelated
Economic recession and alcoholrelated harm Peter Anderson Barcelona, 15 June 2010. On the one hand, as incomes reduce, you might expect alcohol consumption to go down But, on the one hand, as dislocation
More informationBig Data for Population Health and Personalised Medicine through EMR Linkages
Big Data for Population Health and Personalised Medicine through EMR Linkages Zheng-Ming CHEN Professor of Epidemiology Nuffield Dept. of Population Health, University of Oxford Big Data for Health Policy
More informationTable 1. Underlying causes of death related to alcohol consumption, International Classification of Diseases, Ninth Revision
ONS - Defining alcohol-related deaths Note: This document was used for discussion with selected topic experts between November 2005 and January 2006. Release on National Statistics website: 18 July 2006
More informationThe Impact of Alcohol
Alcohol and Tobacco Smoking cigarettes and drinking alcohol are behaviors that often begin in adolescence. Although tobacco companies are prohibited from advertising, promoting, or marketing their products
More informationRisk Factors for Alcoholism among Taiwanese Aborigines
Risk Factors for Alcoholism among Taiwanese Aborigines Introduction Like most mental disorders, Alcoholism is a complex disease involving naturenurture interplay (1). The influence from the bio-psycho-social
More informationAZERBAIJAN. Lower-middle Income Data source: United Nations, data range 1999-2006
AZERBAIJAN SOCIOECONOMIC CONTEXT Total population 8,406,000 Annual population growth rate 0.6% Population 15+ years 76% Adult literacy rate 98.8% Population in urban areas 52% Income group (World bank)
More informationReview of Eliminating occupational cancer in Europe and globally by J. Takala
Review of Eliminating occupational cancer in Europe and globally by J. Takala There primary concerns of this manuscript are outlined below. More detail discussion of these points is presented on the following
More informationAlcohol Related Harm in Ireland. A Health Service Executive Report
A Health Service Executive Report April 2008 TABLE OF CONTENTS 1.0 INTERNATIONAL EVIDENCE...1 1.1 Alcohol harm to the drinker...1 1.2 Alcohol harm to other people...3 2.0 ALCOHOL RELATED HARM IN IRELAND...4
More informationTAJIKISTAN. Recorded adult (15+) alcohol consumption by type of alcoholic beverage (in % of pure alcohol), 2005
TAJIKISTAN SOCIOECONOMIC CONTEXT Total population 6,640,000 Annual population growth rate 1.3% Population 15+ years 61% Adult literacy rate 99.5% Population in urban areas 25% Income group (World bank)
More informationHealth Science / Anatomy Exam 1 Study Guide
THIS EXAM WILL ONLY COVER ALCOHOL AND TOBACCO LECTURES Alcohol What is Alcohol? Alcohol is a depressant Contains intoxicating substance called ethyl alcohol or ethanol Alcohol use Approximately 59.8% of
More informationThe Burden of Cancer in Asia
P F I Z E R F A C T S The Burden of Cancer in Asia Medical Division PG283663 2008 Pfizer Inc. All rights reserved. Printed in USA/December 2008 In 2002, 4.2 million new cancer cases 39% of new cases worldwide
More informationAUSTRALIAN VIETNAM VETERANS Mortality and Cancer Incidence Studies. Overarching Executive Summary
AUSTRALIAN VIETNAM VETERANS Mortality and Cancer Incidence Studies Overarching Executive Summary Study Study A u s t ra l i a n N a t i o n a l S e r v i c e V i e t n a m Ve t e ra n s : M o r t a l i
More informationNumber. Source: Vital Records, M CDPH
Epidemiology of Cancer in Department of Public Health Revised April 212 Introduction The general public is very concerned about cancer in the community. Many residents believe that cancer rates are high
More informationAlcohol Screening, Brief Intervention and Referral: A Clinical Tool
Alcohol Screening, Brief Intervention and Referral: A Clinical Tool Dr. Ryan Sommers Family Physician Medical Officer of Health, NSHA Dalhousie Family Medicine Refresher Nov 27 th 2015 Disclosures None
More informationRisk of alcohol. Peter Anderson MD, MPH, PhD, FRCP Professor, Alcohol and Health, Maastricht University Netherlands. Zurich, 4 May 2011
Risk of alcohol Peter Anderson MD, MPH, PhD, FRCP Professor, Alcohol and Health, Maastricht University Netherlands Zurich, 4 May 2011 Lifetime risk of an alcoholrelated death (1/100) 16.0 14.0 12.0 10.0
More informationAlcohol consumption among elderly European Union citizens
Expert Conference on Alcohol and Health 21 22 September 2009 Stockholm, Sweden Alcohol consumption among elderly European Union citizens Health effects, consumption trends and related issues Mats Hallgren
More informationAlcohol Facts and Statistics
Alcohol Facts and Statistics Alcohol Use in the United States: Prevalence of Drinking: In 2012, 87.6 percent of people ages 18 or older reported that they drank alcohol at some point in their lifetime;
More informationNETHERLANDS (THE) Recorded adult per capita consumption (age 15+) Last year abstainers
NETHERLANDS (THE) Recorded adult per capita consumption (age 15+) 14 12 Litres of pure alcohol 1 8 6 4 Beer Spirits Wine 2 1961 1965 1969 1973 1977 1981 1985 1989 1993 1997 21 Year Sources: FAO (Food and
More informationJESSE HUANG ( 黄 建 始 ),MD,MHPE,MPH,MBA Professor of Epidemiology Assistant President
Breast Cancer Epidemiology i in China JESSE HUANG ( 黄 建 始 ),MD,MHPE,MPH,MBA Professor of Epidemiology Assistant President Chinese Academy of Medical Sciences Peking Union Medical College Medical Center
More informationRisk factors and public health in Denmark Summary report
Risk factors and public health in Denmark Summary report Knud Juel Jan Sørensen Henrik Brønnum-Hansen Prepared for Risk factors and public health in Denmark Summary report Knud Juel Jan Sørensen Henrik
More informationJAMAICA. Recorded adult per capita consumption (age 15+) Last year abstainers
JAMAICA Recorded adult per capita consumption (age 15+) 6 5 Litres of pure alcohol 4 3 2 Beer Spirits Wine 1 1961 1965 1969 1973 1977 1981 1985 1989 1993 1997 21 Sources: FAO (Food and Agriculture Organization
More informationThe Economic Benefits of Risk Factor Reduction in Canada
The Economic Benefits of Risk Factor Reduction in Canada Tobacco Smoking, Excess Weight, Physical Inactivity and Alcohol Use Public Health 2015 May 26, 2015 Risk Factors in High-Income North America Ranked
More informationInvestigating Community Cancer Concerns--Deer Park Community Advisory Council, 2008
Investigating Community Cancer Concerns--Deer Park Community Advisory Council, 2008 David R. Risser, M.P.H., Ph.D. David.Risser@dshs.state.tx.us Epidemiologist Cancer Epidemiology and Surveillance Branch
More informationScientific Facts on. Psychoactive Drugs. Tobacco, Alcohol, and Illicit Substances
page 1/5 Scientific Facts on Psychoactive Drugs Tobacco, Alcohol, and Illicit Substances Source document: WHO (2004) Summary & Details: GreenFacts Context - Psychoactive drugs such as tobacco, alcohol,
More informationBooklet B The Menace of Alcohol
The Menace of Alcohol This report has been designed so that you consider the effects of excessive drinking. It has been compiled from a series of websites from around the world, all of which are reputable
More informationDeterminants, Key Players and Possible Interventions
Major in Human Health, Nutrition and Environment, FS 2010 Public Health Concepts Determinants, Key Players and Possible Interventions David Fäh Aims Have an idea about which parameters can influence health
More informationAn Investigation of Alcohol Metabolizing Enzyme Genes in Chinese Alcoholics With Pancreatitis,, Cirrhosis of Liver, and Avascular Necrosis of Hip
An Investigation of Alcohol Metabolizing Enzyme Genes in Chinese Alcoholics With Pancreatitis,, Cirrhosis of Liver, and Avascular Necrosis of Hip Joints Introduction Maezawa et al., have reported that
More informationAnalysis of Population Cancer Risk Factors in National Information System SVOD
Analysis of Population Cancer Risk Factors in National Information System SVOD Mužík J. 1, Dušek L. 1,2, Pavliš P. 1, Koptíková J. 1, Žaloudík J. 3, Vyzula R. 3 Abstract Human risk assessment requires
More informationAction Plan. on Youth Drinking and on Heavy Episodic Drinking (Binge Drinking) (2014-2016)
Action Plan on Youth Drinking and on Heavy Episodic Drinking (Binge Drinking) (2014-2016) Endorsed by the Committee on National Alcohol Policy and Action (CNAPA) on 16 September 2014 1 1 Introduction 1.1.
More informationARGENTINA. Recorded adult per capita consumption (age 15+) Last year abstainers in Buenos Aires
ARGENTINA Recorded adult per capita consumption (age 15+) 2 18 16 Litres of pure alcohol 14 12 1 8 6 4 2 1961 1965 1969 1973 1977 1981 1985 1989 1993 1997 21 Beer Spirits Wine Sources: FAO (Food and Agriculture
More informationALCO H O L AN D H EALTH THE EFFECTS OF MODERATE, REGULAR ALCOHOL CONSUMPTION
ALCO H O L AN D H EALTH THE EFFECTS OF MODERATE, REGULAR ALCOHOL CONSUMPTION ISBN 2-9807330-6-7 Legal deposit 2005 A l c o h o l a n d H e a l t h THE HEALTH BENEFITS OF MODERATE AND REGULAR ALCOHOL CONSUMPTION
More informationAlcohol Facts and Statistics
Alcohol Facts and Statistics Alcohol Use in the United States:» Prevalence of Drinking: In 2014, 87.6 percent of people ages 18 or older reported that they drank alcohol at some point in their lifetime;
More informationARTICLE #1 PLEASE RETURN AT THE END OF THE HOUR
ARTICLE #1 PLEASE RETURN AT THE END OF THE HOUR Alcoholism By Mayo Clinic staff Original Article: http://www.mayoclinic.com/health/alcoholism/ds00340 Definition Alcoholism is a chronic and often progressive
More informationAlcohol and Brain Damage
Alcohol and Brain Damage By: James L. Holly, MD O God, that men should put an enemy in their mouths to steal away their brains! That we should, with joy, pleasance, revel, and applause, transform ourselves
More informationDietary Fiber and Alcohol. Nana Gletsu Miller, PhD Spring 2014
Dietary Fiber and Alcohol Nana Gletsu Miller, PhD Spring 2014 Dietary Fiber It is the complex carbohydrate in plants that can not be broken down by human digestive enzymes Sources Grains Fruits and Vegetables
More informationCancer incidence and mortality in Europe, 2004
Original article Annals of Oncology 16: 481 488, 2005 doi:10.1093/annonc/mdi098 Cancer incidence and mortality in Europe, 2004 P. Boyle* & J. Ferlay International Agency for Research on Cancer, Lyon, France
More informationCancer incidence and mortality patterns in Europe: Estimates for 40 countries in 2012
an Journal of Cancer (2013) 49, 1374 1403 Available at www.sciencedirect.com journalhomepage:www.ejcancer.info Cancer incidence and mortality patterns in : Estimates for 40 countries in 2012 J. Ferlay
More informationAlcohol abuse and smoking
Alcohol abuse and smoking Important risk factors for TB? 18 th Swiss Symposium on tuberculosis Swiss Lung Association 26 Mach 2009 Knut Lönnroth Stop TB Department WHO, Geneva Full implementation of Global
More informationLOW-RISK DRINKING GUIDELINES A GUIDE FOR PHYSICIANS AND HEALTH CARE PROFESSIONALS
LOW-RISK DRINKING GUIDELINES A GUIDE FOR PHYSICIANS AND HEALTH CARE PROFESSIONALS 7 INTRODUCTION This guide is intended for physicians and health care professionals to help them explain the low-risk drinking
More informationBoth alcohol and tobacco use are associated with
CANCER RISK ASSOCIATED WITH ALCOHOL AND TOBACCO USE: FOCUS ON UPPER AERO DIGESTIVE TRACT AND LIVER Claudio Pelucchi, Sc.D.; Silvano Gallus, Sc.D.; Werner Garavello, M.D.; Cristina Bosetti, Sc.D.; and Carlo
More informationGeneral and Abdominal Adiposity and Risk of Death in Europe
Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke General and Abdominal Adiposity and Risk of Death in Europe Tobias Pischon Department of Epidemiology German Institute of Human Nutrition Potsdam-Rehbruecke
More informationPatterns of Alcohol Consumption Debating Paper
HEALTH SCRUTINY PANEL 8 TH FEBRUARY 2011 Patterns of Alcohol Consumption Debating Paper The Health Scrutiny Panel agreed the following terms of reference for the review into patterns of alcohol consumption:
More informationAlcohol-use disorders: alcohol dependence. Costing report. Implementing NICE guidance
Alcohol-use disorders: alcohol dependence Costing report Implementing NICE guidance February 2011 (February 2011) 1 of 37 NICE clinical guideline 115 This costing report accompanies the clinical guideline:
More informationPOSITION STATEMENT. Alcohol and cancer risk. Key messages and recommendations. Introduction. Evidence linking alcohol and cancer
POSITION STATEMENT Alcohol and cancer risk Key messages and recommendations Alcohol use is a cause of cancer. Any level of alcohol consumption increases the risk of developing an alcohol-related cancer;
More informationAlcoholism I. INTRODUCTION II. DEVELOPMENT
Alcoholism I. INTRODUCTION Alcoholism, chronic and usually progressive illness involving ingesting inappropriately high levels of ethyl alcohol, whether in the form of familiar alcoholic beverages or as
More informationAlcohol Use and healthy aging: the need for monitoring and prevention to add life to years
Alcohol Use and healthy aging: the need for monitoring and prevention to add life to years Emanuele Scafato, Istituto Superiore di Sanità, Rome, ITALY Director Population Health Unit CNESPS Osservatorio
More informationUK Chief Medical Officers Alcohol Guidelines Review Summary of the proposed new guidelines
UK Chief Medical Officers Alcohol Guidelines Review Summary of the proposed new guidelines January 2016 2 UK Chief Medical Officers Alcohol Guidelines Review Summary of the proposed new guidelines 1. This
More informationCancer in Ireland 2013: Annual report of the National Cancer Registry
Cancer in 2013: Annual report of the National Cancer Registry ABBREVIATIONS Acronyms 95% CI 95% confidence interval APC Annual percentage change ASR Age standardised rate (European standard population)
More informationAlcohol and drugs prevention, treatment and recovery: why invest?
Alcohol and drugs prevention, treatment and recovery: why invest? 1 Alcohol problems are widespread 9 million adults drink at levels that increase the risk of harm to their health 1.6 million adults show
More informationHow To Get Healthy
Dietary Fiber and Alcohol Nana Gletsu Miller, PhD Fall 2-13 Dietary Fiber It is the complex carbohydrate in plants that can not be broken down by human digestive enzymes Sources Grains Fruits and Vegetables
More informationProtecting and improving the nation s health. Alcohol treatment in England 2013-14
Protecting and improving the nation s health Alcohol treatment in England 2013-14 October 2014 About Public Health England Public Health England exists to protect and improve the nation s health and wellbeing,
More informationPart 4 Burden of disease: DALYs
Part Burden of disease:. Broad cause composition 0 5. The age distribution of burden of disease 6. Leading causes of burden of disease 7. The disease and injury burden for women 6 8. The growing burden
More informationKey trends nationally and locally in relation to alcohol consumption and alcohol-related harm
Key trends nationally and locally in relation to alcohol consumption and alcohol-related harm November 2013 1 Executive Summary... 3 National trends in alcohol consumption and alcohol-related harm... 5
More informationEvidence Regarding the Level of Alcohol Consumption Considered to be Low-Risk for Men and Women
Evidence Regarding the Level of Alcohol Consumption Considered to be Low-Risk for Men and Women By Eric Single, Mary Jane Ashley, Susan Bondy, James Rankin and Jürgen Rehm, with the assistance of Maureen
More informationFrequently asked questions on the procedure for the re-assessment of glyphosate within the framework of the EU active substance review
Frequently asked questions on the procedure for the re-assessment of glyphosate within the framework of the EU active substance review BfR FAQ, 12 November 2015 Active substances used in pesticides are
More informationEU citizens attitudes towards alcohol
Special Eurobarometer 331 European Commission EU citizens attitudes towards alcohol Fieldwork: October 2009 Publication: April 2010 Special Eurobarometer 331 / Wave TNS Opinion & Social This survey was
More informationThe relation between different dimensions of alcohol consumption and burden of disease: an overviewadd_2899 817..843
MONOGRAPH doi:10.1111/j.1360-0443.2010.02899.x The relation between different dimensions of alcohol consumption and burden of disease: an overviewadd_2899 817..843 Jürgen Rehm 1,2,3, Dolly Baliunas 1,2,
More information2. Local Data to reduce Alcohol Related Harm and Comparison Groups
Alcohol Treatment Needs Assessment 2012-2013 1. Introduction Using the JSNA Support pack for alcohol prevention, treatment & recovery, which presents data from the Local Alcohol Profiles for England (LAPE),
More informationHow to keep health risks from drinking alcohol to a low level: public consultation on proposed new guidelines
How to keep health risks from drinking alcohol to a low level: public consultation on proposed new guidelines January 2016 2 How to keep health risks from drinking alcohol to a low level: public consultation
More informationTO REDUCE HEALTH RISKS
National Health and Medical Research Council AUSTRALIAN GUIDELINES TO REDUCE HEALTH RISKS FROM DRINKING ALCOHOL Australian Guidelines TO REDUCE HEALTH RISKS from Drinking Alcohol W O R KING TO BUILD A
More informationAlcohol and cancer March 2013
Alcohol and cancer March 2013 Contents Introduction 1 The relationship between alcohol and cancer 3 > What is the evidence that drinking alcohol can cause cancer? 3 > How does alcohol cause cancer? 3
More informationEVIDENCE ABOUT HEALTH EFFECTS OF MODERATE ALCOHOL CONSUMPTION: REASONS FOR SCEPTICISM AND PUBLIC HEALTH IMPLICATIONS
EVIDENCE ABOUT HEALTH EFFECTS OF MODERATE ALCOHOL CONSUMPTION: REASONS FOR SCEPTICISM AND PUBLIC HEALTH IMPLICATIONS By Sven Andréasson, Tanya Chikritzhs, Frida Dangardt, Harold Holder, Timothy Naimi and
More informationStatistics on Alcohol England, 2014
Statistics on Alcohol England, 2014 Published 29 May 2014 This product may be of interest to stakeholders, policy officials, commissioners and members of the public to gain a comprehensive picture of society
More informationPolicy Brief. Tackling Harmful Alcohol Use Economics and Public Health Policy. Directorate for Employment, Labour and Social Affairs.
Policy Brief Tackling Harmful Alcohol Use Economics and Public Health Policy May 2015 Directorate for Employment, Labour and Social Affairs OECD s new flagship report examines the economic and public health
More informationWINE FOR YOUR HEALTH: TRUTH AND MYTH. Cutting through the Clutter about Heart Health
WINE FOR YOUR HEALTH: TRUTH AND MYTH Cutting through the Clutter about Heart Health Julia M. Dostal, PhD Executive Director, LEAF Council on Alcoholism & Addictions Board of Directors, National Council
More informationMesothelioma Trends as Predictors of the Asbestos- Related Lung Cancer Burden
Mesothelioma Trends as Predictors of the Asbestos- Related Lung Cancer Burden Valerie McCormack UICC World Cancer Congress Montreal August 2012 Outline Background Estimating the lung cancer mortality burden
More informationLeukemia and Exposure to Ionizing Radiation
Leukemia and Exposure to Ionizing Radiation Summary: Strong evidence has been recorded of a possible connection between forms of leukemia and exposure to ionizing radiation. This evidence is based upon
More informationAsbestos related cancers
New cancer cases 1954-215 in Finland, Men Pukkala et al. 26 Asbestos related cancers Panu Oksa, MD, docent Course on asbestos-related diseases Tartu 4-5.12.26 Asbestos related cancer / FIOH / PO / 1.1.27
More informationThe Health and Well-being of the Aboriginal Population in British Columbia
The Health and Well-being of the Aboriginal Population in British Columbia Interim Update February 27 Table of Contents Terminology...1 Health Status of Aboriginal People in BC... 2 Challenges in Vital
More informationAlcohol Addiction. Introduction. Overview and Facts. Symptoms
Alcohol Addiction Alcohol Addiction Introduction Alcohol is a drug. It is classed as a depressant, meaning that it slows down vital functions -resulting in slurred speech, unsteady movement, disturbed
More informationSkin Cancer: The Facts. Slide content provided by Loraine Marrett, Senior Epidemiologist, Division of Preventive Oncology, Cancer Care Ontario.
Skin Cancer: The Facts Slide content provided by Loraine Marrett, Senior Epidemiologist, Division of Preventive Oncology, Cancer Care Ontario. Types of skin Cancer Basal cell carcinoma (BCC) most common
More information. Alcohol Focus Scotland. Response to Tackling poverty, Inequality and deprivation in Scotland
. Alcohol Focus Scotland. Response to Tackling poverty, Inequality and deprivation in Scotland Introduction Problem drinking and social groupings. Alcohol prob.lems affect people from all social groups.
More informationDiagnosis and Treatment of Common Oral Lesions Causing Pain
Diagnosis and Treatment of Common Oral Lesions Causing Pain John D. McDowell, DDS, MS University of Colorado School of Dentistry Chair, Oral Diagnosis, Medicine and Radiology Director, Oral Medicine and
More informationPROMOTE MENTAL HEALTH AND PREVENT SUBSTANCE ABUSE
1 PROMOTE MENTAL HEALTH AND PREVENT SUBSTANCE ABUSE 2 MENTAL HEALTH IN ALBANY-RENSSELAER 3 Mental Health Summary Albany-Rensselaer has an estimated: 70,000 adults (18+yrs.) with Any Mental Illness ; 28,400
More informationFacts About Alcohol. Addiction Prevention & Treatment Services
Facts About Alcohol Addiction Prevention & Treatment Services Table of Contents Facts about alcohol: What is harmful involvement with alcohol?... 2 What is alcohol dependence?... 3 What Is BAC?... 4 What
More informationTest Your Breast Cancer Knowledge
Test Your Breast Cancer Knowledge Regular exams and a good understanding can help defend against breast cancer, yet many women hold outdated ideas about their own breast cancer risk. Take this quiz to
More informationALCOHOL AND SOCIETY 2014
ALCOHOL AND SOCIETY 2014 THEME: THE EFFECTS OF LOW-DOSE ALCOHOL CONSUMPTION A RESEARCH REPORT FROM IOGT-NTO AND THE SWEDISH SOCIETY OF MEDICINE 1 A SWEDISH LANGUAGE VERSION OF THIS REPORT IS ALSO AVAILABLE
More informationCANCER EXPLAINED. Union for International Cancer Control Union Internationale Contre le Cancer
MEDIA FACTSHEET CANCER EXPLAINED What is cancer? Cancer is a disease which occurs when changes in a group of normal cells within the body lead to uncontrolled growth causing a lump called a tumour; this
More informationSummary of the risk management plan (RMP) for Otezla (apremilast)
EMA/741412/2014 Summary of the risk management plan (RMP) for Otezla (apremilast) This is a summary of the risk management plan (RMP) for Otezla, which details the measures to be taken in order to ensure
More informationWhat the experts say: The consensus of scientific opinion
What the experts say: The consensus of scientific opinion AMTA relies on the expert judgment of independent public health authorities, such as the World Health Organization, for assessments of safety and
More informationinflammation of the pancreas and damage to the an increased risk of hypertension, stroke and Table 7.1: Classification of alcohol consumption
H E A LT H SURVEY Alcohol Consumption 7 Alcohol Consumption N AT I O N A L Introduction Excessive alcohol consumption is associated with inflammation of the pancreas and damage to the an increased risk
More informationAlcoholism and Drug Abuse in China By David J. Powell, Ph.D. President, International Center for Health Concerns, Inc.
Alcoholism and Drug Abuse in China By David J. Powell, Ph.D. President, International Center for Health Concerns, Inc. Introduction Alcohol and drug abuse and dependence are worldwide concerns. In China,
More informationAppendix: Description of the DIETRON model
Appendix: Description of the DIETRON model Much of the description of the DIETRON model that appears in this appendix is taken from an earlier publication outlining the development of the model (Scarborough
More informationSubstance Abuse in the Elderly
Substance Abuse in the Elderly Roseann Mulligan DDS, MS Definitions: Abuse: to use wrongly, badly, excessively; to misuse Misuse: to use incorrectly or improperly; to abuse Types of Substances Implicated
More information