& INTELLECTUAL PROPERTY

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1 LEADERS LEAGUE Intelligence Report & Directory Series INNOVATION, TECHNOLOGY & INTELLECTUAL PROPERTY Har wor "u we take a 5 years te.:. to competitio MARKET INTELLIGENCE REPORT PART 1 - INNOVATION INDUSTRY 1 - Hardware The mad scramble for innovation Software Cloud computing, the top priority for IT departments Telecom Mobile phones, a world -wide market Internet & media An audience, my kingdom for an audience! Pharmaceutical & Biotechs challenges R &D in search of development The biggest pharmaceutical companies Conditional financing PART 2 - ADDING VALUE THROUGH IP PROTECTION 1 - Patents overview Patent applications back on the up Counterfeit drug dealers Trademarks overview Trademark registration takes off again PART 3 RANKING THE BEST ADVISORS BY COUNTRIES KEY PLAYERS DIRECTORY Patents & Trademark Attorneys Law firms David Burke Google emichel Ginestet Pfizer Nicolaz Foucaud Microsoft Pierre Steiblen Michel detalhouët Francis Gurry - Qualcomm Hewlett- Packard r Zhong Chongyu I Thomas Senger Denis Lucquin 1!!.1 Ethypharm Kofax Sofinnova Partners Benoit Battistelli Gerhard Bauer ^ Pier Giovanni Wannest European Patent Office INTA F. Pirelli 6_ C ``f' / ' a Mai AN ANNUAL REPORT FROM LEADERS LEAGUE

2 FRANCE BEST LAW S: PATENT LITIGATION 1E1 I Véron & Associés Allen & Overy Cousin & Associés Duclos Thorne Mollet- Viéville Gaultier Lakits Josse Szleper Gide Loyrette Nouel Hirsch & Associés Howrey' Armengaud- Guerlain Bardehle Pagenberg Bird & Bird Casalonga Avocats Lavoix Avocats Linklaters Armfelt Clifford Chance D'Alverny Dement & Associés de Gaulle Fleurance & Associés DLA Piper Pierre Véron, Isabelle Romet. Thomas Bouvet, Sabine Age Pierre Lenoir, Laétitia Bénard Pierre Cousin, Myriam Moatty, Jean -Martin Chevalier, Sandrine Bouvier Rayon, Damien Remy Thierry Mollet- Viéville, Pascal Lefort, Eléonore Gaspar, Thomas Cuche Geoffroy Gaultier, Dariusz Szleper, Anne Lakits -Josse Arnaud Michel, Grégoire Triet, Emmanuel Larere Marc -Roger Hirsch, Gérard - Gabriel Lamoureux, Denis Schertenleib Marina Cousté, François Jonquéres Jacques Armengaud, Stéphane Guerlain, Elisabeth Berthet Maillols Julien Fréneaux, Olivier Legrand, Michèle Lesage -Catel Yves Bizollon Arnaud Casalonga, Caroline Casalonga, Jean - Christophe Guerrini Serge Binn, Cyrille Amar, Grégoire Goussu Marianne Schaffner EGAvocats I Escande Hogan Lovells Marchais de Candé Taylor Wessing * Effective March 15, 2011, the partners of Howrey LLP voted to dissolve the law rm. Véron & Associés: succession guaranteed for the market leader This firm, founded by Pierre Véron, has become the outright benchmark in the patent litigation field. It owes this recognition to its organisation, which is fully devoted to patent affairs, and its capacity to handle the most complex cases in their entirety, thanks to significant internal human and physical resources - a scientific consultant, an economic litigation consultant, a graphic designer and an in -house translation service work alongside the firm's team of 13 lawyers. This legal team also includes three partners of recognised expertise (Isabelle Romet, Thomas Bouvet and Sabine Age), wisely selected by founding partner has to ensure the firm's continuation and the organisation's response capacity. Pierre Véron Allen & Overy: dominating cross - border litigation The intellectual property department of Allen & Overy Paris enjoys the advantage of belonging to one of the largest international law firms and thus particularly distinguishes itself on cross - border litigation. The department has a team of around ten lawyers whose specialisations include, in particular, pharmaceutical patent litigation. This field is, in fact,the area of excellence of Pierre Lenoir, one of the firm's leading partners. In addition, Laetitia Bénard, who became a partner in 2009, brings her extensive experience in trademarks to the team and is thus helping to develop the activity within the practice, throughout France and the rest of Europe. Pierre Lenoir Linklaters: adopting an upmarket positioning Marianne Schaffner - co- director of the British giant's media wing and partner in the firm since 2000 has in just a few years become a respected and renowned figure in the patent litigation field. The firm works with large organisations in the pharmaceutical, car and food industries and is involved in major trademark litigation affairs. Having established a positioning for cases with high added value, the team has also played a role in the reconciliation of major telecommunications and energy players. Marianne Schaffner 2011 INTELLIGENCE REPORT & DIRECTORY SERIES I LEADERS LEAGUE 1 103

3 RANKING THE BEST ADVISORS BY COUNTRIES FRANCE FRANCE BEST IP ATTORNEYS: TRADEMARKS Beau de Loménie Novagraaf Regimbeau Dreyfus & associés Egyp Germain & Maureau Inlex Conseil Lavoix Plasseraud T -Mark Casalonga -Josse Cabinet Degret Cabinet Vidon Markplus International Pro -Mark Santarelli Schmit- Chrétien Aurélia Marie O. Boland, P. de Boisse, C.Baillet, B. Egasse - Michaille, A. -C. Schihin, G. Mortreux E. Roux, M. Levieils, J.-R. Callon de Lamarck, C. Texier, F. Ahner, J. Warcoin Nathalie Dreyfus, Emmanuel Harrar Martine Dehaut, Virginie Zancan Ph. Maureau, G. Bernard, H. Pouzet, W. Lobelson, M. Flechard Franck Soutoul, Eric Schahs Catherine Levalet Guylène Kiesel Le Cosquer François Deschamps, Valérie Dorey, Nadine Royer Axel Casalonga, Gérard Dossmann, Francis Zapalowicz Jacques Degret, Manuel Degret, Bruno Raibaut, Fabrice Bircker Soazig Thémoin Corinne Allard- Dornaletche, Paul -Eric Allard, Caroline Geffroy - Redon, P. Charrier Alain Berthet, Bénédicte Devevey, Aurèle Sarda- Beaujouan, Nicolas Moreau Herbert Lewitter, Eric le Bihan Jérôme Chrétien FRANCE BEST IP ATTORNEYS: PATENTS Beau de Loménie Casalonga -Josse Lavoix Plasseraud Regimbeau Santarelli Egyp Novagraaf Bravalex Hirsch Pochait Marks & Clerk Brema Loyer Cabinet Didier Martin Cabinet Lepeudry Cabinet Orés Cabinet Vidon Dejade & Biset Philippe Hubert, Jean - Jacques Joly, Didier Intés, Pierre -Louis Désormière, François Délumeau A. Casalonga, G. Dossmann, F. Zapalowicz, O. Delprat, V. Martin- Charbonneau Ph. Blot, A. Colombet, B. Domenego, E. Habasque, C. Jacobson, G. Myon D. Boulinguiez, C. Nargolwalla, F. Bérogin, B. Loisel, E. Burbaud, S. Verdure, R. Fleurance, A. Hassine J. Warcoin, F. Ahner, Ch. Texier, J. Collin, E. Le Forestier, J -R Callon de Lamarck, M. Levieils, F. Tetaz, F. Faivre -Petit L. Santarelli, T. Caen, F. Lepelletier- Beaufond, H. Lewitter, B. Ouantin, H. Stankoff, A. Bonnans, M. Petit, O. Thrierr Anne Desaix, Carol Almond - Martin, Julia Andral -Ziurys J.-L. Somnier, J. -P. Bentz, T. Pichat, M. Broydé, J. -B. Busnel, E. Enderlin, M. Bethenod Gérard Poulin, Jean Lehu, Philippe Audier, Eric Augarde, Philippe Ahner Loin Depelley, Murielle Khairallah, François Pochart, Yves Reinhardt, J-C Vieillefosse Ch. Nguyen- Van -Yen, S. Esselin, L. Lucas, J. -M. Breda, I. Dudouit, M.-P. Henriot, M. Guérin Germain & Maureau Harlé et Phélip liras Conseil Lynde & Associés Nony 104 I 2011 INTELLIGENCE REPORT & DIRECTORY SERIES I LEADERS LEAGUE

4 Beau de Loménie: French excellence achieves European success Aurélia Marie Driven by its success as French market leader and its four French offices, the firm has successfully set up branches in Germany and the United Kingdom and continues to enjoy the support of a large network of representatives. Thanks to this expansion, the organisation, with its 220 experts, generates 50% of its turnover from foreign client business. The firm is primarily focused on patents and through the achievements of its five specialised partners (Didier Intès, Jean Jacques Joly, Philippe Hubert, François Delumeau and Pierre - Louis Désormière), now manages over 55,000 of them. Since 2003, the trademarks and designs activity has grown spectacularly under the impetus of Aurélia Marie, the firm's sixth partner. Regimbeau: one of the widest ranges of services on offer gka4 Marc Levieils The patents affairs team is led by six partners whose complementary expertise allows them to cover the entire range of cutting -edge technologies: chemical science, life sciences, physics, NITC, mechanics, etc. In the trademarks field, Marc Levieils and Evelyne Roux are capable of handling an equally wide range of business and have been involved in notable affairs in the advertising, pharmaceuticals, food, banking and retail industries. Thanks to this diversity, the 75- year -old firm has maintained its position as leader and continues to deliver growth year after year. Plasseraud: at the forefront of innovation for more than a century A Guylène Kiesel le Cosquer Although Plasseraud has one of the longest histories in its field, the 1906 founded firm proved over the last decade to be as dynamic as ever, with successive openings of new offices in Lyon, Lille, Toulouse, Dijon and even Shanghai. The firm has also successfully chosen to develop and diversify its expertise by expanding its subsidiary Contratak - specialised in anti - counterfeiting issues - and its Fivalor division, which handles the assessment of industrial property rights. Plasseraud also remains a benchmark consultancy for trademarks - thanks to the expertise of Guylène Kiesel le Cosquer -and patents, which are currently still the core activity of the firm. Lavoix: protecting IP through a multi - industry network This founded firm was already a steadfast institution in the French IP arena; however, since developing ties with Binn & associés - now Lavoix avocats - at the end of 2008, it has become one of the most powerful organisations with the most comprehensive range of services. While the two entities continue to be managed independently, the 200 members of staff work together closely sharing a network of 70 qualified professionals comprising lawyers, industrial property consultants, engineers, legal advisors, etc. The firm's Industrial Property Consulting (IPC) branch, which is particularly renowned for patent affairs, is also well -established in the Trademarks and Designs segment. Philippe Blot Inlex: a creative approach to trademark law Franck Soutoul The history of Inlex is above all marked by bold choices. Upon establishing the organisation in 1995, Franck Soutoul and Eric Schahl decided to focus solely on Trademarks and Designs thus differentiating themselves from the competition which was still focused essentially on patent law. They then ventured a local positioning strategy by establishing a particularly dense national network of branches. The firm now employs no less than 70 people in its Parisian branch and across its regional offices in Cannes, Bordeaux, Reims, Nantes, Marseille and Beaune. Always at the cutting -edge of innovation, the firm is constantly expanding its offer of services to stay abreast with the diversification of IP- related issues. This dynamic approach has led Inlex to become one of the major players of the French market INTELLIGENCE REPORT & DIRECTORY SERIES I LEADERS LEAGUE 1 105

5 . t RANKING THE BEST ADVISORS BY COUNTRIES FRANCE FRANCE BEST LAWS: TRADEMARK LITIGATION 1 1 u Armengaud- Guerlain Bird & Bird Escande Gaultier Lakits -Josse Szleper Gide Loyrette Noue! Cabinet Greffe Casalonga Avocats Cousin & Associés De Gaulle Fleurance & Associés Duclos Thorne Mollet- Viéville Hirsch & Associés Hogan Lovells Howrey* Marchais de Candé Natal á Fajgenbaum & Associés 1v1 ^ *"fis-..a, v Antoine & Benoliel Baker & McKenzie Cabinet Bertrand Cabinet Hoffman Christian Le Stanc Cléry Avocats Deprez, Guignol & Associés DLA Piper Herbert Smith Jacobacci Jones Day J.P. Karsenty & Associés Salans Altana August & Debouzy BCTG & Associés Bardehle Pagenberg BMH Avocats DS Avocats Field Fisher Waterhouse Gilbey Delorey Granrut Avocats Alain Bensoussan Avocats Cabinet Bouchera FTPA Hollier- Larousse & Associés HW &H Lavoix Avocats Linklaters Morgan Lewis Nomos PDGB _.. Poulmaire Jacob SNR Denton Winston & Shawn ",?a, g.'. Jacques Armengaud, Stéphane Guerlain Isabelle Leroux Michel -Paul Escande Geoffroy Gaultier, Anne Lakits Josse, Dariusz Szleper Arnaud Michel, Grégoire Triet, Emmanuel Larere François Greffe, Pierre Greffe A. Casalonga, C. Casalonga, J. -C. Guerrini, P. Comte, K. Dimidjan- Lecomte, M. Gabriel Pierre Cousin, Myriam Moatty, Jean -Martin Chevalier, Sandrine Bouvier- Rayon, Damien Rémy Louis de Gaulle, Frank Valentin, Julien Horn Thierry Mollet- Viéville, Pascal Lefort, Eléonore Gaspar, Thomas Cuche Gérard - Gabriel Lamoureux, Marc -Roger Hirsch M. A. de Dampierre, D. Ménard, D. Taylor, X. Buffet Delmas d'autane, W. Maxwell Marina Cousté Guillaume Marchais, Patrice de Candé, Julien Blanchard, Maria Luisa Arce Torrecilla Fabienne Fajgenbaum, Serge Lederman Muriel Antoine Lalance, Sylvie Benoliel -Claux Virginie Ulmann, Jean - François Bretonnière, Tania Kern Patrick Bertrand Serge Hoffman, Pierre Hoffman, Emmanuelle Hoffman -Alias Christian Le Stanc (Montpellier) Alain Cléry Pierre Deprez, Vincent Fauchoux, Frédéric Dumont.r.. s" a"e.z t, %;.n<.. Laurence Julien -Raes, Patrick Boiron, Bruce Mee, Carol A.F. Umhoefer Alexandra Néri Charles de Haas. Jean Mathieu Bertho Emmanuel Baud Martine Karsenty- Ricard, Béatrice Moreau - Margotin, Jean -Pierre Karsenty Gérard Delile, David Masson Pierre Lubet, Claire Bernier Kami Haeri, Mahasti Razavi, Florence Chafiol- Chaumont Gaulle Bloret Pucci, Jean - Philippe Thibault Julien Fréneaux, Valérie Perrichon, Stéphanie Legrand, Olivier Legrand, Michele Lesage -Catel Martin Hauser Catherine Verneret, Claire Bertheux Scone, Bertrand Potot, Jean -Marc Leonelli Bruno Ducoulombier, Franck Veisse Rebecca Delorey, Richard Gilbey, Nathalie Ruffin, Richard Metzger Richard Milchior, Jean Castelain, Emmanuel Sordet, Anne Cousin Laurence Tellier Loniewski, Claudine Salomon, Anne Sophie Cantreau Vanessa Bouchara Philippe Pochet, Fabrice Lorvo, Antoine Gautier Sauvagnac Christian Hollier- Larousse, Annette Sion Christophe Chapoullié Serge Binn, Cyrille Amar, Grégoire Goussu Marianne Schaffner Catherine Muyl Hélena Delabarre, Eric Lauvaux, Armelle Fourlon Benjamin Jacob Julie Jacob Stefan Naumann Nathalie Hadjadj- Cazier, Patrick Dunaud, Emmanuel Drai Effective March 15, 2011, the partners of Howrey LLP voted to dissolve the law firm. um INTELLIGENCE REPORT a DIRECTORY SERIES I LEADERS LEAGUE

6 Gide Loyrette Nouel: a heavyweight with a competitive edge 'a. Grégoire Triet With around 20 lawyers, the French- founded international legal giant has one of the most significant intellectual property teams in Europe. This size advantage, combined with a reputation for quality, gained on prestigious accounts such as Mattel, Philip Morris and Adidas, has led Gide to become a powerful player in the Parisian IP world. The department is spearheaded by three partners: Emmanuel Larere and Arnaud Michel represent both trademark and patent matters, while Grégoire Triet completes the structure by contributinghis top -class patent litigation expertise. Bird & Bird: the intangible assets professionals This practice has built a reputation for itself around its internationally deployed IP -IT expertise. The Parisian IP team - led by renowned trademark practitioner, Isabelle Leroux, and patent litigation specialist, Yves Bizollon can therefore rely on the support of a global network of 130 experts. The team recently made a name for itself through its involvement in highly- sensitive cases for clients including L'Oreal, SFR, Coca -Cola and the European Central Bank. Moreover, in 2009 the practice strengthened its involvement with stakeholders from the international health field with the arrival of Alain Gorny and his team within its life sciences division. Isabelle Leroux Duclos Thorne Mollet - Viéville: a reputation stretching beyond French borders Of the 25 lawyers comprising this French practice, founded in 1966, approximately 15 are involved in industrial property law matters on a full -time basis. The firm's influential leader, Thierry Mollet -Viéville, whose prior position was president of the International Association for the Protection of Intellectual Property (IAPIP), continues to distinguish himself in the patent litigation field. The three partners working alongside him - Éléonore Gaspar, Pascal Lefort and Thomas Cuche - handle trademark, design and model issues for an extremely international clientele across a wide range of sectors from audio -visual and luxury goods to the automotive and pharmaceutical industries. Thierry Mollet - Viéiville De Gaulle Fleurance & Associés: a prominent IP litigation player Positioned as a full- service provider the French firm De Gaulle Fleurance & Associés differentiates itself by applying a strategic, cross cutting approach to litigation, in all of its key fields of activity. Industrial Property is, of course, no exception. Head of the litigation division, Louis de Gaulle represents major corporate groups such as Air Liquide. Frank Valentin and Julien Horn, on the other hand, have made a name for themselves in the trademark law branch, particularlyfor the banking, insurance, art and technology sectors. Finally, Jean -Marie Job an extremely active member of the advisory branch, focuses on patent law especially for the pharmaceutical sector. Louis de Gaulle Deprez Guignot & associés: an unusualorganisation serving big name clients Fifteen years ago this general legal practice, already looking to the future, decided to make IP the key focus of its growth strategy by setting up a specialised trademark law department. This trademark hub is resolutely innovative in that it aims to provide its clients with a full range of services for managing their portfolio. In order to make this possible, the intellectual property team, with their complementary skills, also provide their support to the hub. Spearheaded by three partners Pierre Deprez, Vincent Fauchoux and Frederic Dumont the IP team also comprises nine lawyers and three legal experts who work with some of the biggest names from the luxury goods, media and food industries. Pierre Deprez LMC - Marchais de Candé: focused on advising and managing portfolios 1.r V JI Founded in 1997 by former industrial property consultants, Marchais de Candé has become one of the most dynamic Paris outfits. Led by four partners, (Guillaume Marchais, Patrice de Candé, Julien Blanchard and Maria Luisa Arce - Torrecilla) and eight team members, the firm is divided into two core activities of equal importance: submission and consulting (trademarks, models and domain names), and litigation. Having developed a strong presence representing major players from the luxury goods and insurance sectors, as well as the pharmaceutical industry, the firm now intends to focus on patent law development. Guillaume Marchais 2011 INTELLIGENCE REPORT & DIRECTORY SERIES I LEADERS LEAGUE 1 107