Agilent 6000 Series LC/MS Solutions CONFIDENCE IN QUANTITATIVE AND QUALITATIVE ANALYSIS

Save this PDF as:
 WORD  PNG  TXT  JPG

Size: px
Start display at page:

Download "Agilent 6000 Series LC/MS Solutions CONFIDENCE IN QUANTITATIVE AND QUALITATIVE ANALYSIS"

Transcription

1 Agilent 6000 Series LC/MS Solutions CONFIDENCE IN QUANTITATIVE AND QUALITATIVE ANALYSIS

2 AGILENT 6000 SERIES LC/MS SOLUTIONS UNRIVALED ACHIEVEMENT AT EVERY LEVEL The Agilent 6000 Series of LC/MS instruments embodies more than 40 years of innovative development in mass spectrometry, with systems that set the standard for reliability, flexibility, and sensitivity. Engineering Excellence in Every Aspect of Performance Innovative LC/MS platforms comprising single quad, triple quad, TOF, and Q-TOF technologies Leading HPLC and UHPLC instruments and columns that match your analytical needs and budget The widest range of interchangeable ionization sources ensure the right mode for your compounds of interest 24/7 Agilent reliability to maximize your lab s uptime and productivity Solutions that Span Critical Applications Environmental analysis Food safety analysis Forensic toxicology Biomolecule analysis Metabolite identification Proteomics and metabolomics Pharma and biopharma QA/QC Drug discovery and development 2

3 FASTER SEPARATIONS, BETTER DATA, AND GREATER PRODUCTIVITY Many technological developments illustrate Agilent s commitment to innovative design and performance. No matter where you look in our portfolio, the performance and reliability serve to demonstrate that Agilent is serious about mass spectrometry. Powerful HPLC and UHPLC Separations Agilent 6000 Series LC/MS systems integrate seamlessly with our 1290 Infinity LC to routinely deliver results. Agilent MS instruments are the only systems that can accurately capture the unmatched throughput of ultrafast UHPLC separations. Novel HPLC-Chip Technology Agilent 6000 Series LC/MS systems are fully compatible with our innovative HPLC-Chip technology a plug-and-play alternative to complicated conventional nanoflow source configuration. HPLC-Chip/MS delivers robust, reproducible, and ultra-sensitive results from small sample volumes. Agilent 1290 Infinity LC system HPLC-Chip technology MassHunter Software Comprehensive MassHunter software controls Agilent LC/TOF, LC/Q-TOF, and LC/triple-quad instruments, as well as Agilent HPLC modules and the Capillary Electrophoresis system. The same Data Analysis software is common for GC/MS, ICP-MS and LC/MS platforms. MassHunter Software 3

4 AGILENT 6100 SERIES SINGLE QUADRUPOLE LC/MS UNPRECEDENTED PERFORMANCE AND PROVEN RELIABILITY From routine QC to research-level applications, Agilent 6100 Series Single Quadrupole LC/MS systems deliver superior MS data quality in an easy-to-use, space-saving package. With configurations to fit all budgets, the industry s most popular single quad LC/MS complements your existing LC detectors and integrates seamlessly with Agilent s ChemStation LC control. Faster acquisition speeds let you take full advantage of the higher throughput of today s faster UHPLC chromatography with fast scan speed. Ultra-fast ion polarity switching lets you obtain both positive and negative spectra, providing maximum information from a single injection essential for second-wide UHPLC peaks. Faster injection-to-injection cycle time lets you run more samples per hour. Supports walk-up operation, mass-based fraction collection, and data conversion to MassHunter. Supports front end separation techniques such as SFC, CE and direct sampling devices. Agilent 6100 Series Single Quadrupole LC/MS systems the sensitivity, selectivity, and information content of mass spectrometry in an amazingly compact package. 4

5 AGILENT 6200 SERIES ACCURATE-MASS TOF LC/MS ULTRA HIGH DEFINITION TOF TECHNOLOGY FOR UNPARALLELED CONFIDENCE Whether you are confirming synthetic compounds, profiling biomarkers, identifying impurities, screening for pesticides, or characterizing intact proteins, the Agilent 6230 Accurate-Mass Time-of-Flight (TOF) LC/MS system delivers unmatched speed and performance in a compact benchtop instrument. Sub ppm mass accuracy improves confidence and reduces false positives. High resolving power distinguishes desired compounds from interferences. Fast data acquisition rates ensure compatibility with fast chromatography and high-throughput methodologies. Up to five orders of in-spectrum dynamic range reveals trace-level targets even in the presence of vastly more abundant compounds. Low picogram on-column sensitivity finds impurities or biomarkers at extremely low concentrations. Accurate intact protein MW determination, in combination with MassHunter BioConfirm software, allow rapid QC of recombinant biotherapeutics. Automatic tuning and automated introduction of internal reference solution ensure consistent mass accuracy and reliable molecular weight measurements over wide temperature ranges. Ultra High Definition TOF technology brings together proprietary innovations to achieve the performance required for screening applications. 5

6 AGILENT 6400 SERIES TRIPLE QUADRUPOLE LC/MS SUPERIOR SENSITIVITY, EASY UPGRADEABILITY The Agilent 6400 Series Triple Quadrupole LC/MS Systems provide superior sensitivity and renowned reliability for your quantitative applications in pharmaceutical ADME/DMPK studies, biomarker validation, clinical research, food safety, forensics, toxicology, and environmental analyses. The 6420 offers affordable entry into the world of triple quadrupole analysis. The 6460 brings the Jet Stream Technology with extended mass range and even greater sensitivity. The 6490 incorporates novel ifunnel technology for ultra-trace analysis with attogram limits of quantitation and an unprecedented six orders of linearity for your most demanding quantitative analyses. The new standard for triple-quad sensitivity. Agilent 6490 with ifunnel technology delivers unmatched sensitivity Triggered MRM (tmrm) combines fast and sensitive MRM quantitation with the generation of a product ion spectrum for library searching and compound screening and confirmation. Ultra fast MRM acquisition and ion polarity switching using an innovative collision cell to eliminate cross-talk and enable short MRM dwell times, together with fast polarity switching, ensures compatibility with UHPLC analyses. Higher full scan speed allows you to take full advantage of today s high throughput UHPLC chromatography. Dynamic MRM (dmrm) simplifies method development and allows thousands of compounds to be quantified in a single method with optimal sensitivity and reproducibility. MassHunter Optimizer software automatically optimizes MRM conditions for both small molecules and peptides. 6

7 AGILENT 6500 SERIES ACCURATE-MASS Q-TOF LC/MS ROUTINE ACCURATE MASS, SUPERIOR MS/MS SENSITIVITY, UNCOMPROMISED PERFORMANCE The Agilent 6500 Series Quadrupole Time-of-Flight LC/MS Systems provide routine sub ppm accurate mass, superior MS/MS sensitivity and uncompromised performance for a wide range of applications. The 6530 Q-TOF provides excellent value for everyday routine use with robust operation. The 6540 Q-TOF provides enhanced resolution and mass accuracy. The 6550 Q-TOF incorporates ifunnel technology to deliver low femtogram sensitivity for trace analyses. The 6560 ion mobility Q-TOF provides an added dimension of mobility separation for complex samples. It enables direct determination of collision cross sections with superior mobility resolution, sensitivity and preservation of conformers. Sub ppm mass accuracy dramatically reduces uncertainty, improves database search scores and molecular formula generation of unknowns, while minimizing false positives. Enhanced resolving power provides added confidence that you are detecting all mass peaks of interest in complex samples. Superior MS/MS sensitivity helps you identify very low-abundance compounds at femtogram levels. Dynamic range of up to five orders in-spectrum improves detection of low-abundance compounds in the presence of other major components. Fast scan rates provide excellent spectral quality for fast UHPLC and HPLC-Chip separations. The world s most sensitive Q-TOF. The Agilent 6550 ifunnel Q-TOF LC/MS delivers the lowest limits of detection over the widest linear dynamic range all in a benchtop system. 7

8 1290 INFINITY LC SYSTEM INFINITELY BETTER LC/MS RESULTS Superior separations are key to obtaining the best results from your 6000 Series LC/MS. Agilent s 1290 Infinity LC System delivers best-in-class UHPLC speed and resolution. The ideal front end for any Agilent mass spectrometer, the 1290 Infinity LC system allows you to optimize your separations to meet the needs of your analysis. UHPLC speed and unprecedented peak capacity and resolution combine to eliminate co-elution and peak overlap. ZORBAX RRHD 1.8 μm columns deliver the resolution and peak definition required for critical LC/MS analyses, with robust, reliable performance over the extended operating range of the 1290 Infinity LC System. The extremely wide operating power range of Agilent s 1290 Infinity LC System from 1200 bar at 2 ml/minute to 800 bar at 5 ml/minute enables Agilent s 1290 Infinity LC System to deliver faster separations without loss of chromatographic resolution. ZORBAX RRHD Agilent HPLC-Chip Maximum Sensitivity for Low-level Samples Working seamlessly with the Infinity Series Nanoflow LC system, Agilent s revolutionary HPLC-Chip integrates the sample enrichment and separation columns of a nanoflow LC system with the connections and nanospray tip used in electrospray mass spectrometry all on a reusable microfluidic chip about the size of a microscope slide. Solvent and sample delivery to the chip, high-pressure switching of flows, and automated chip loading and positioning in the MS source are accomplished by Agilent s HPLC-Chip Cube MS interface. An embedded RF tag tracks usage and operating parameters. High sensitivity ensures low-level sample fidelity Narrower, better-defined chromatographic peaks allow confident MS identification Reusable chips with multiple functionalities enable easy, interchangeable workflows with maximum uptime and productivity 8 Agilent 1290 Infinity LC system Agilent HPLC-Chip and Chip Cube interface

9 IFUNNEL, HPLC-CHIP, AND CROSS-PLATFORM TECHNOLOGY TAKE YOUR ANALYSIS TO NEW LIMITS Pioneering developments from Agilent push the performance envelope of LC/MS into new realms of sensitivity and productivity. Agilent ifunnel technology Proven ifunnel Technology Agilent s proprietary ifunnel Technology combines three Agilent innovations: Jet Stream sample introduction, providing high-efficiency ESI ion generation and focusing; a hexabore capillary; and a unique dual-stage ion funnel assembly. Together, these technologies reduce neutrals and increase ion sampling to dramatically improve overall signal within the system, delivering significant increases in sensitivity compared with conventional instruments. Cross-platform Technology All Agilent LC/MS instruments share common interface which allows users of one instrument type to rapidly become familiar with new instruments. Other features help ensure cross-platform compatibility; the collision cell in the Q-TOF and triple-quad instruments lets you set up MRM experiments on one instrument and simply transfer them to another, while interchangeable ion sources assure repeatable, consistent ion formation on any platform. 9

10 MASSHUNTER WORKSTATION SOFTWARE SIMPLIFY AND STREAMLINE YOUR DATA ANALYSIS From instrument tuning to final report, Agilent s MassHunter Workstation software was designed to make MS analyses faster, easier, and more productive. Its familiar, intuitive user interface is common to all Agilent MS platforms. Integration with Applications and Workflows Compound-centric data processing and intuitive, workflow driven navigation shorten the path between acquiring raw analytical data and getting answers. MassHunter s Qualitative Analysis and Quantitative Analysis software modules have a customizable user interface, provide for unprecedented automation, and integrate seamlessly with other application-specific MassHunter software. Mass Profiler Professional Uses powerful statistical and mathematical models to analyze multiple MS data types, enabling you to easily identify differences between sample groups. MassHunter Study Manager and Optimizer software Modules Automate the complete analysis process from compound optimization through reporting. MassHunter software can optionally be integrated with WATSON or other LIMS systems. MassHunter BioConfirm software Couples feature finding and deconvolution algorithms with sequence matching tools for fast, accurate characterization of proteins, synthetic peptides, nucleotides, and their variants. Spectrum Mill for MassHunter Workstation Quickly identifies proteins and peptides through fast database searches and provides automatic and manual match validation; also supports label-free and stable-isotope-based quantitation strategies. Software and Services MassHunter software provides comprehensive tools to help you address the requirements of GLP/GMP and 21 CFR Part 11 compliance for quantitative analysis. Agilent qualification services shorten the time between installation and productive operation. MassHunter Software 10

11 LC/MS APPLICATION KITS FAST-TRACK YOUR PRODUCTIVITY Agilent s Pesticide, Forensic Toxicology, and Veterinary Drug LC/MS Application Kits are designed to help you spend less time on setup and configuration and more time generating the highest quality results from new technologies. Customers report that they can save days or even weeks of typical start-up time and effort in the lab. Minimize the Need for Tedious Manual Method Development with Predeveloped Databases and Libraries Multiresidue analysis of pesticides, veterinary drugs, and forensic toxicology compounds is challenging for two reasons: low concentrations and a large number of analytes to be monitored and quantified. With so many variables to consider, it can be difficult to find a solid starting point for method development. A Faster, Easier Way to Develop Customized Screening Methods Agilent s Pesticide, Forensic Toxicology, and Veterinary Drug LC/MS Application Kits are truly unique, because much of the development work has already been completed. The kits feature easy-to-use examples that show you how to set up screening methods on your triple quadrupole, TOF, or Q-TOF instrument, and quickly adapt them to your specific needs. It also includes: An accurate mass or tmrm database and library for hundreds or thousands of compounds. Pre-tested analytical methods are provided for targeted or untargeted screening of analytes that are routinely monitored around the world. 11

12 Learn more Buy online Find an Agilent customer center USA and Canada Europe Asia Pacific Research use only. Information, descriptions, and specifications in this publication are subject to change without notice. Agilent Technologies shall not be liable for error contained herein or for incidental or consequential damages in connection with the furnishing, performance, or use of this material. This information is subject to change without notice. Agilent Technologies, Inc Published in the USA, March 27, EN

API 3200 LC/MS/MS SYSTEM. Performance, productivity and value combined

API 3200 LC/MS/MS SYSTEM. Performance, productivity and value combined API 3200 LC/MS/MS SYSTEM Performance, productivity and value combined API 3200 LC/MS/MS SYSTEM Reliability, reproducibility, and confidence in your data. With an unmatched heritage of technological innovation

More information

Simultaneous qualitative and quantitative analysis using the Agilent 6540 Accurate-Mass Q-TOF

Simultaneous qualitative and quantitative analysis using the Agilent 6540 Accurate-Mass Q-TOF Simultaneous qualitative and quantitative analysis using the Agilent 654 Accurate-Mass Q-TOF Technical Overview Authors Pat Perkins Anabel Fandino Lester Taylor Agilent Technologies, Inc. Santa Clara,

More information

WATERS QUANTITATIVE ANALYSIS solutions

WATERS QUANTITATIVE ANALYSIS solutions More sensitivity. More speed. What more can you ask for in a complete quantitative analysis solution? WATERS QUANTITATIVE ANALYSIS solutions THE CHALLENGE OF QUANTITATIVE ANALYSIS Tandem mass spectrometry,

More information

AxION edoor. Web-Based, Open-Access Mass Spectrometry Software

AxION edoor. Web-Based, Open-Access Mass Spectrometry Software AxION edoor Web-Based, Open-Access Mass Spectrometry Software 2 AxION edoor is the open-access software solution for today s fast-paced laboratory. It is designed to operate and optimize the management

More information

Overview. Introduction. AB SCIEX MPX -2 High Throughput TripleTOF 4600 LC/MS/MS System

Overview. Introduction. AB SCIEX MPX -2 High Throughput TripleTOF 4600 LC/MS/MS System Investigating the use of the AB SCIEX TripleTOF 4600 LC/MS/MS System for High Throughput Screening of Synthetic Cannabinoids/Metabolites in Human Urine AB SCIEX MPX -2 High Throughput TripleTOF 4600 LC/MS/MS

More information

amazon SL Innovation with Integrity Setting New Standards in Performance, Simplicity and Value Ion Trap MS

amazon SL Innovation with Integrity Setting New Standards in Performance, Simplicity and Value Ion Trap MS amazon SL Setting New Standards in Performance, Simplicity and Value Innovation with Integrity Ion Trap Best-In-Class Ion Trap Mass Spectrometer for Routine Analysis The amazon SL entry-level system is

More information

INTEGRATED TECHNOLOGY TO SEE THE WHOLE PICTURE. AxION iqt GC/MS/MS

INTEGRATED TECHNOLOGY TO SEE THE WHOLE PICTURE. AxION iqt GC/MS/MS AxION iqt GC/MS/MS INTEGRATED TECHNOLOGY TO SEE THE WHOLE PICTURE IDENTIFY WHAT YOU RE LOOKING FOR (AND EVEN WHAT YOU RE NOT) The GC/MS/MS Solution for the Work You Do The ideal solution for industrial,

More information

Agilent LCMS products and the application strategies in veterinary drug analysis

Agilent LCMS products and the application strategies in veterinary drug analysis Agilent LCMS products and the application strategies in veterinary drug analysis Experience A New Level of Confidence Ma Xin 马 鑫 LCMS Application Engineer Internal Sales Training - The new 6495 QQQ LC/MS

More information

NUVISAN Pharma Services

NUVISAN Pharma Services NUVISAN Pharma Services CESI MS Now available! 1st CRO in Europe! At the highest levels of quality. LABORATORY SERVICES Equipment update STATE OF THE ART AT NUVISAN CESI MS Now available! 1st CRO in Europe!

More information

MultiQuant Software 2.0 for Targeted Protein / Peptide Quantification

MultiQuant Software 2.0 for Targeted Protein / Peptide Quantification MultiQuant Software 2.0 for Targeted Protein / Peptide Quantification Gold Standard for Quantitative Data Processing Because of the sensitivity, selectivity, speed and throughput at which MRM assays can

More information

AB SCIEX TOF/TOF 4800 PLUS SYSTEM. Cost effective flexibility for your core needs

AB SCIEX TOF/TOF 4800 PLUS SYSTEM. Cost effective flexibility for your core needs AB SCIEX TOF/TOF 4800 PLUS SYSTEM Cost effective flexibility for your core needs AB SCIEX TOF/TOF 4800 PLUS SYSTEM It s just what you expect from the industry leader. The AB SCIEX 4800 Plus MALDI TOF/TOF

More information

The Scheduled MRM Algorithm Enables Intelligent Use of Retention Time During Multiple Reaction Monitoring

The Scheduled MRM Algorithm Enables Intelligent Use of Retention Time During Multiple Reaction Monitoring The Scheduled MRM Algorithm Enables Intelligent Use of Retention Time During Multiple Reaction Monitoring Delivering up to 2500 MRM Transitions per LC Run Christie Hunter 1, Brigitte Simons 2 1 AB SCIEX,

More information

Outline of MassHunter Software Session

Outline of MassHunter Software Session Outline of MassHunter Software Session 1. Overview MassHunter Software Programs 2. From ChemStation to MassHunter (Optional) 3. MassHunter Qual and Quant (?) 4. MassHunter for LC/MS Demo Find by Methods:

More information

Increasing Quality While Maintaining Efficiency in Drug Chemistry with DART-TOF MS Screening

Increasing Quality While Maintaining Efficiency in Drug Chemistry with DART-TOF MS Screening Increasing Quality While Maintaining Efficiency in Drug Chemistry with DART-TOF MS Screening Application Note Forensics Author Erin Shonsey Director of Research Alabama Department of Forensic Science Abstract

More information

Application Note # LCMS-62 Walk-Up Ion Trap Mass Spectrometer System in a Multi-User Environment Using Compass OpenAccess Software

Application Note # LCMS-62 Walk-Up Ion Trap Mass Spectrometer System in a Multi-User Environment Using Compass OpenAccess Software Application Note # LCMS-62 Walk-Up Ion Trap Mass Spectrometer System in a Multi-User Environment Using Compass OpenAccess Software Abstract Presented here is a case study of a walk-up liquid chromatography

More information

In-Depth Qualitative Analysis of Complex Proteomic Samples Using High Quality MS/MS at Fast Acquisition Rates

In-Depth Qualitative Analysis of Complex Proteomic Samples Using High Quality MS/MS at Fast Acquisition Rates In-Depth Qualitative Analysis of Complex Proteomic Samples Using High Quality MS/MS at Fast Acquisition Rates Using the Explore Workflow on the AB SCIEX TripleTOF 5600 System A major challenge in proteomics

More information

MRMPilot Software: Accelerating MRM Assay Development for Targeted Quantitative Proteomics

MRMPilot Software: Accelerating MRM Assay Development for Targeted Quantitative Proteomics MRMPilot Software: Accelerating MRM Assay Development for Targeted Quantitative Proteomics With Unique QTRAP and TripleTOF 5600 System Technology Targeted peptide quantification is a rapidly growing application

More information

A Navigation through the Tracefinder Software Structure and Workflow Options. Frans Schoutsen Pesticide Symposium Prague 27 April 2015

A Navigation through the Tracefinder Software Structure and Workflow Options. Frans Schoutsen Pesticide Symposium Prague 27 April 2015 A Navigation through the Tracefinder Software Structure and Workflow Options Frans Schoutsen Pesticide Symposium Prague 27 April 2015 Kings day in The Netherlands 1 Index Introduction Acquisition, Method

More information

MassHunter for Agilent GC/MS & GC/MS/MS

MassHunter for Agilent GC/MS & GC/MS/MS MassHunter for Agilent GC/MS & GC/MS/MS Next Generation Data Analysis Software Presented by : Terry Harper GC/MS Product Specialist 1 Outline of Topics Topic 1: Introduction to MassHunter Topic 2: Data

More information

LC-MS/MS for Chromatographers

LC-MS/MS for Chromatographers LC-MS/MS for Chromatographers An introduction to the use of LC-MS/MS, with an emphasis on the analysis of drugs in biological matrices LC-MS/MS for Chromatographers An introduction to the use of LC-MS/MS,

More information

Overview. Triple quadrupole (MS/MS) systems provide in comparison to single quadrupole (MS) systems: Introduction

Overview. Triple quadrupole (MS/MS) systems provide in comparison to single quadrupole (MS) systems: Introduction Advantages of Using Triple Quadrupole over Single Quadrupole Mass Spectrometry to Quantify and Identify the Presence of Pesticides in Water and Soil Samples André Schreiber AB SCIEX Concord, Ontario (Canada)

More information

Application Note # LCMS-81 Introducing New Proteomics Acquisiton Strategies with the compact Towards the Universal Proteomics Acquisition Method

Application Note # LCMS-81 Introducing New Proteomics Acquisiton Strategies with the compact Towards the Universal Proteomics Acquisition Method Application Note # LCMS-81 Introducing New Proteomics Acquisiton Strategies with the compact Towards the Universal Proteomics Acquisition Method Introduction During the last decade, the complexity of samples

More information

Increasing the Multiplexing of High Resolution Targeted Peptide Quantification Assays

Increasing the Multiplexing of High Resolution Targeted Peptide Quantification Assays Increasing the Multiplexing of High Resolution Targeted Peptide Quantification Assays Scheduled MRM HR Workflow on the TripleTOF Systems Jenny Albanese, Christie Hunter AB SCIEX, USA Targeted quantitative

More information

Thermo Scientific ExactFinder Software

Thermo Scientific ExactFinder Software mass spectrometry Thermo Scientific ExactFinder Software Workflow software for routine targeted and general unknown screening Unifies qualitative and quantitative high-resolution accurate mass workflows

More information

Chemical Analysis. Simulated Distillation Analyzers. A full range of simulated Distillation Analysis Solution. Gas Chromatography.

Chemical Analysis. Simulated Distillation Analyzers. A full range of simulated Distillation Analysis Solution. Gas Chromatography. Chemical Analysis Simulated Distillation Analyzers A full range of simulated Distillation Analysis Solution think forward Gas Chromatography Bruker Simulated Distillation Analyzers Bruker s range of Simulated

More information

EKSIGENT EKSPERT NANOLC 400. Unmatched flexibility for low flow LC/MS

EKSIGENT EKSPERT NANOLC 400. Unmatched flexibility for low flow LC/MS EKSIGENT EKSPERT NANOLC 4 Unmatched flexibility for low flow LC/MS EKSIGENT EKSPERT NANOLC 4 Focused ekspertise In 23, Eksigent changed the way scientists looked at nanoscale chromatography with the introduction

More information

Effects of Intelligent Data Acquisition and Fast Laser Speed on Analysis of Complex Protein Digests

Effects of Intelligent Data Acquisition and Fast Laser Speed on Analysis of Complex Protein Digests Effects of Intelligent Data Acquisition and Fast Laser Speed on Analysis of Complex Protein Digests AB SCIEX TOF/TOF 5800 System with DynamicExit Algorithm and ProteinPilot Software for Robust Protein

More information

Agilent 1290 Infinity LC. Infinitely more powerful

Agilent 1290 Infinity LC. Infinitely more powerful Agilent 9 Infinity LC Infinitely more powerful 9 Agilent 9 Infinity LC Infinitely more powerful. With more than enough power to handle any HPLC or UHPLC challenge, the advanced technology in the Agilent

More information

Accurate Mass Screening Workflows for the Analysis of Novel Psychoactive Substances

Accurate Mass Screening Workflows for the Analysis of Novel Psychoactive Substances Accurate Mass Screening Workflows for the Analysis of Novel Psychoactive Substances TripleTOF 5600 + LC/MS/MS System with MasterView Software Adrian M. Taylor AB Sciex Concord, Ontario (Canada) Overview

More information

HRMS in Clinical Research: from Targeted Quantification to Metabolomics

HRMS in Clinical Research: from Targeted Quantification to Metabolomics A sponsored whitepaper. HRMS in Clinical Research: from Targeted Quantification to Metabolomics By: Bertrand Rochat Ph. D., Research Project Leader, Faculté de Biologie et de Médecine of the Centre Hospitalier

More information

Thermo Scientific Prelude SPLC System FPO. Making LC/MS accessible. to clinical research and toxicology labs

Thermo Scientific Prelude SPLC System FPO. Making LC/MS accessible. to clinical research and toxicology labs Thermo Scientific Prelude SPLC System FPO Making LC/MS accessible to clinical research and toxicology labs Specifically designed to make the power of LC/MS accessible Analysis of target compounds in complex

More information

aurora ICP-MS Innovation with Integrity The Science of Sensitivity ICP-MS

aurora ICP-MS Innovation with Integrity The Science of Sensitivity ICP-MS aurora ICP-MS The Science of Sensitivity Innovation with Integrity ICP-MS Powers the Business of Quantification aurora ICP-MS enhanced value package Bruker s ICP-MS is famous for its innovative and unique

More information

Pesticide residue analysis: New Trends. Michal Godula, Ph.D. EU Marketing Manager Food Safety & Environmental Thermo Fisher Scientific

Pesticide residue analysis: New Trends. Michal Godula, Ph.D. EU Marketing Manager Food Safety & Environmental Thermo Fisher Scientific Pesticide residue analysis: New Trends Michal Godula, Ph.D. EU Marketing Manager Food Safety & Environmental Thermo Fisher Scientific Why pesticide analysis? Extensively used in agriculture to control

More information

Using NIST Search with Agilent MassHunter Qualitative Analysis Software James Little, Eastman Chemical Company Sept 20, 2012.

Using NIST Search with Agilent MassHunter Qualitative Analysis Software James Little, Eastman Chemical Company Sept 20, 2012. Using NIST Search with Agilent MassHunter Qualitative Analysis Software James Little, Eastman Chemical Company Sept 20, 2012 Introduction Screen captures in this document were taken from MassHunter B.05.00

More information

Over 110 new configurations so you never have to choose between speed, resolution, and sensitivity.

Over 110 new configurations so you never have to choose between speed, resolution, and sensitivity. Agilent s newly expanded ZORBAX Rapid Resolution High Throughput (RRHT) and Rapid Resolution (RR) HPLC Column Portfolio Over 110 new configurations so you never have to choose between speed, resolution,

More information

Bruker ToxScreener TM. Innovation with Integrity. A Comprehensive Screening Solution for Forensic Toxicology UHR-TOF MS

Bruker ToxScreener TM. Innovation with Integrity. A Comprehensive Screening Solution for Forensic Toxicology UHR-TOF MS Bruker ToxScreener TM A Comprehensive Screening Solution for Forensic Toxicology Innovation with Integrity UHR-TOF MS ToxScreener - Get the Complete Picture Forensic laboratories are frequently required

More information

Highly Selective Analysis of Steroid Biomarkers using SelexION Ion Mobility Technology

Highly Selective Analysis of Steroid Biomarkers using SelexION Ion Mobility Technology Highly Selective Analysis of Steroid Biomarkers using SelexION Ion Mobility Technology Hua-Fen Liu, Witold Woroniecki, Doina Caraiman, and Yves LeBlanc AB SCIEX, Foster City, USA One of the most challenging

More information

Strategies for Developing Optimal Synchronous SIM-Scan Acquisition Methods AutoSIM/Scan Setup and Rapid SIM. Technical Overview.

Strategies for Developing Optimal Synchronous SIM-Scan Acquisition Methods AutoSIM/Scan Setup and Rapid SIM. Technical Overview. Strategies for Developing Optimal Synchronous SIM-Scan Acquisition Methods AutoSIM/Scan Setup and Rapid SIM Technical Overview Introduction The 5975A and B series mass selective detectors (MSDs) provide

More information

Enhancing GCMS analysis of trace compounds using a new dynamic baseline compensation algorithm to reduce background interference

Enhancing GCMS analysis of trace compounds using a new dynamic baseline compensation algorithm to reduce background interference Enhancing GCMS analysis of trace compounds using a new dynamic baseline compensation algorithm to reduce background interference Abstract The advantages of mass spectrometry (MS) in combination with gas

More information

TotalChrom. Chromatography Data Systems. Streamlining your laboratory workflow

TotalChrom. Chromatography Data Systems. Streamlining your laboratory workflow TotalChrom Chromatography Data Systems Streamlining your laboratory workflow maximize productivity with TotalChrom CDS Acquiring, processing, reporting, reviewing and approving data is a streamlined series

More information

Research-grade Targeted Proteomics Assay Development: PRMs for PTM Studies with Skyline or, How I learned to ditch the triple quad and love the QE

Research-grade Targeted Proteomics Assay Development: PRMs for PTM Studies with Skyline or, How I learned to ditch the triple quad and love the QE Research-grade Targeted Proteomics Assay Development: PRMs for PTM Studies with Skyline or, How I learned to ditch the triple quad and love the QE Jacob D. Jaffe Skyline Webinar July 2015 Proteomics and

More information

MultiQuant Software Version 3.0 for Accurate Quantification of Clinical Research and Forensic Samples

MultiQuant Software Version 3.0 for Accurate Quantification of Clinical Research and Forensic Samples MultiQuant Software Version 3.0 for Accurate Quantification of Clinical Research and Forensic Samples Fast and Efficient Data Review, with Automatic Flagging of Outlier Results Adrian M. Taylor and Michael

More information

A High Throughput Automated Sample Preparation and Analysis Workflow for Comprehensive Forensic Toxicology Screening using LC/MS/MS

A High Throughput Automated Sample Preparation and Analysis Workflow for Comprehensive Forensic Toxicology Screening using LC/MS/MS A High Throughput Automated Sample Preparation and Analysis Workflow for Comprehensive Forensic Toxicology Screening using LC/MS/MS AB SCIEX QTRAP 4500 LC/MS/MS System and Gerstel, Inc. MultiPurpose Sampler

More information

Unique Software Tools to Enable Quick Screening and Identification of Residues and Contaminants in Food Samples using Accurate Mass LC-MS/MS

Unique Software Tools to Enable Quick Screening and Identification of Residues and Contaminants in Food Samples using Accurate Mass LC-MS/MS Unique Software Tools to Enable Quick Screening and Identification of Residues and Contaminants in Food Samples using Accurate Mass LC-MS/MS Using PeakView Software with the XIC Manager to Get the Answers

More information

Waters Core Chromatography Training (2 Days)

Waters Core Chromatography Training (2 Days) 2015 Page 2 Waters Core Chromatography Training (2 Days) The learning objective of this two day course is to teach the user core chromatography, system and software fundamentals in an outcomes based approach.

More information

endless One platform possibilities for DNA, RNA, protein and cell analysis Agilent 2100 Bioanalyzer Our measure is your success.

endless One platform possibilities for DNA, RNA, protein and cell analysis Agilent 2100 Bioanalyzer Our measure is your success. One platform endless possibilities for DNA, RNA, protein and cell analysis Agilent 2100 Bioanalyzer Our measure is your success. products applications software services Agilent 2100 bioanalyzer Applied

More information

Agilent Enhanced Matrix Removal Lipid LOSE THE LIPIDS, FIND YOUR ANALYTES

Agilent Enhanced Matrix Removal Lipid LOSE THE LIPIDS, FIND YOUR ANALYTES Agilent Enhanced Matrix Removal Lipid LOSE THE LIPIDS, FIND YOUR ANALYTES AGILENT ENHANCED MATRIX REMOVAL LIPID ARE LIPIDS WEIGHING YOUR SAMPLES DOWN? Interference from lipids is a problem for labs measuring

More information

Improving the Metabolite Identification Process with Efficiency and Speed: LightSight Software for Metabolite Identification

Improving the Metabolite Identification Process with Efficiency and Speed: LightSight Software for Metabolite Identification Improving the Metabolite Identification Process with Efficiency and Speed: LightSight Software for Metabolite Identification Overview LightSight Software for Metabolite Identification is a complete environment

More information

Introduction to Proteomics 1.0

Introduction to Proteomics 1.0 Introduction to Proteomics 1.0 CMSP Workshop Tim Griffin Associate Professor, BMBB Faculty Director, CMSP Objectives Why are we here? For participants: Learn basics of MS-based proteomics Learn what s

More information

AGILENT S BIOINFORMATICS ANALYSIS SOFTWARE

AGILENT S BIOINFORMATICS ANALYSIS SOFTWARE ACCELERATING PROGRESS IS IN OUR GENES AGILENT S BIOINFORMATICS ANALYSIS SOFTWARE GENESPRING GENE EXPRESSION (GX) MASS PROFILER PROFESSIONAL (MPP) PATHWAY ARCHITECT (PA) See Deeper. Reach Further. BIOINFORMATICS

More information

Appendix 5 Overview of requirements in English

Appendix 5 Overview of requirements in English Appendix 5 Overview of requirements in English This document is a translation of Appendix 4 (Bilag 4) section 2. This translation is meant as a service for the bidder and in case of any differences between

More information

UHPLC/MS: An Efficient Tool for Determination of Illicit Drugs

UHPLC/MS: An Efficient Tool for Determination of Illicit Drugs Application Note: 439 UHPLC/MS: An Efficient Tool for Determination of Illicit Drugs Guifeng Jiang, Thermo Fisher Scientific, San Jose, CA, USA Key Words Accela UHPLC System MSQ Plus MS Detector Drugs

More information

SCION SQ Series GC-MS

SCION SQ Series GC-MS SCION SQ Series GC-MS The Gas Chromatographers Detector SCION SQ TM GC-MS The SCION SQ series GC-MS systems combine innovative engineering with detailed cutomer requirements to produce a truly innovative

More information

Laboratory Equipment Management INVENTORY MANAGEMENT

Laboratory Equipment Management INVENTORY MANAGEMENT Laboratory Equipment Management CREATE AN ACCURATE AND POWERFUL LAB EQUIPMENT INVENTORY Effective asset management strategies start with an accurate inventory of your laboratory equipment. Agilent CrossLab

More information

泛 用 蛋 白 質 體 學 之 質 譜 儀 資 料 分 析 平 台 的 建 立 與 應 用 Universal Mass Spectrometry Data Analysis Platform for Quantitative and Qualitative Proteomics

泛 用 蛋 白 質 體 學 之 質 譜 儀 資 料 分 析 平 台 的 建 立 與 應 用 Universal Mass Spectrometry Data Analysis Platform for Quantitative and Qualitative Proteomics 泛 用 蛋 白 質 體 學 之 質 譜 儀 資 料 分 析 平 台 的 建 立 與 應 用 Universal Mass Spectrometry Data Analysis Platform for Quantitative and Qualitative Proteomics 2014 Training Course Wei-Hung Chang ( 張 瑋 宏 ) ABRC, Academia

More information

DRUG METABOLISM. Drug discovery & development solutions FOR DRUG METABOLISM

DRUG METABOLISM. Drug discovery & development solutions FOR DRUG METABOLISM DRUG METABLISM Drug discovery & development solutions FR DRUG METABLISM Fast and efficient metabolite identification is critical in today s drug discovery pipeline. The goal is to achieve rapid structural

More information

Accelerate your Quantitative LC/MS Workflows with a Fully Integrated UHPLC-QQQ Platform

Accelerate your Quantitative LC/MS Workflows with a Fully Integrated UHPLC-QQQ Platform Accelerate your Quantitative LC/MS Workflows with a Fully Integrated UHPLC-QQQ Platform Remco Swart Pittcon March 8-12, 2015 1 The world leader in serving science Outline Thermo Scientific Vanquish UHPLC

More information

Quantitative analysis of anabolic steroids in control samples from food-producing animals using a column-switching LC-HESI-MS/MS assay

Quantitative analysis of anabolic steroids in control samples from food-producing animals using a column-switching LC-HESI-MS/MS assay PO-CON1484E Quantitative analysis of anabolic steroids in control samples from food-producing animals using a column-switching ASMS 014 TP85 David R. Baker 1, John Warrander 1, Neil Loftus 1, Simon Hird

More information

Cliquid ChemoView 3.0 Software Simple automated analysis, from sample to report

Cliquid ChemoView 3.0 Software Simple automated analysis, from sample to report PRODUCT BULLETIN Cliquid ChemoView 3.0 Software for Routine Screening and Quantitation Cliquid ChemoView 3.0 Software Simple automated analysis, from sample to report KEY FEATURES Secure user login that

More information

Retrospective Analysis of a Host Cell Protein Perfect Storm: Identifying Immunogenic Proteins and Fixing the Problem

Retrospective Analysis of a Host Cell Protein Perfect Storm: Identifying Immunogenic Proteins and Fixing the Problem Retrospective Analysis of a Host Cell Protein Perfect Storm: Identifying Immunogenic Proteins and Fixing the Problem Kevin Van Cott, Associate Professor Dept. of Chemical and Biomolecular Engineering Nebraska

More information

impact II Innovation with Integrity Get the full picture the first time UHR-TOF MS

impact II Innovation with Integrity Get the full picture the first time UHR-TOF MS impact II Get the full picture the first time Innovation with Integrity UHR-TOF MS Sensational Capabilities of impact II Optimize your LC-MS methods without compromising performance: impact II delivers

More information

Specifications. MassHunter WorkStation for Agilent 7700 Series ICP-MS. Specifications: MassHunter Workstation (G7211A) for the Agilent 7700 Series

Specifications. MassHunter WorkStation for Agilent 7700 Series ICP-MS. Specifications: MassHunter Workstation (G7211A) for the Agilent 7700 Series Specifications MassHunter WorkStation for Agilent 7700 Series ICP-MS Specifications: MassHunter Workstation (G7211A) for the Agilent 7700 Series The ICP-MS MassHunter Workstation for the Agilent 7700 Series

More information

Thermo Scientific Vanquish UHPLC System. Revolutionize Your. UHPLC Experience

Thermo Scientific Vanquish UHPLC System. Revolutionize Your. UHPLC Experience Thermo Scientific Vanquish UHPLC System Revolutionize Your UHPLC Experience We feel that achieving better performance is not the same as spending more effort. We know that every breakthrough starts with

More information

Metabolomic Profiling of Accurate Mass LC-MS/MS Data to Identify Unexpected Environmental Pollutants

Metabolomic Profiling of Accurate Mass LC-MS/MS Data to Identify Unexpected Environmental Pollutants Metabolomic Profiling of Accurate Mass LC- Data to Identify Unexpected Environmental Pollutants André Schreiber 1, David Cox 1, Nadia Pace 1, Christopher Borton 2 1 AB SCIEX, Concord, ntario, Canada; 2

More information

RapidFire High-throughput MS technology. Enhancing Drug Discovery Turning Mass Specs into Plate Readers

RapidFire High-throughput MS technology. Enhancing Drug Discovery Turning Mass Specs into Plate Readers RapidFire High-throughput MS technology Enhancing Drug Discovery Turning Mass Specs into Plate Readers 1 Drug Discovery with RapidFire Target Selection High-throughput Target Screening (HTS) Lead Optimization

More information

Ultra Fast UHPLC-LCMSMS Method Development in Clinical Drug Monitoring

Ultra Fast UHPLC-LCMSMS Method Development in Clinical Drug Monitoring PO-CON1359E Ultra Fast UHPLC-LCMSMS Method Development in HPLC 2013 MASS-09 Anja Grüning 1 ; Brigitte Richrath 1 ; Klaus Bollig 2 ; Sven Vedder 1 ; Robert Ludwig 1 1 Shimadzu Europa GmbH, Duisburg, Germany;

More information

Using Natural Products Application Solution with UNIFI for the Identification of Chemical Ingredients of Green Tea Extract

Using Natural Products Application Solution with UNIFI for the Identification of Chemical Ingredients of Green Tea Extract Using Natural Products Application Solution with UNIFI for the Identification of Chemical Ingredients of Green Tea Extract Lirui Qiao, 1 Rob Lewis, 2 Alex Hooper, 2 James Morphet, 2 Xiaojie Tan, 1 Kate

More information

Mass Spectrometry Based Proteomics

Mass Spectrometry Based Proteomics Mass Spectrometry Based Proteomics Proteomics Shared Research Oregon Health & Science University Portland, Oregon This document is designed to give a brief overview of Mass Spectrometry Based Proteomics

More information

Agilent Metabolomics Workflow

Agilent Metabolomics Workflow Agilent Metabolomics Workflow Discovery Workflow Guide Prepare for an experiment Find features Import and organize data Create an initial analysis Advanced operations Define the experiment Create method

More information

Thermo Scientific GC-MS Data Acquisition Instructions for Cerno Bioscience MassWorks Software

Thermo Scientific GC-MS Data Acquisition Instructions for Cerno Bioscience MassWorks Software Thermo Scientific GC-MS Data Acquisition Instructions for Cerno Bioscience MassWorks Software Mark Belmont and Alexander N. Semyonov, Thermo Fisher Scientific, Austin, TX, USA Ming Gu, Cerno Bioscience,

More information

PosterREPRINT AN LC/MS ORTHOGONAL TOF (TIME OF FLIGHT) MASS SPECTROMETER WITH INCREASED TRANSMISSION, RESOLUTION, AND DYNAMIC RANGE OVERVIEW

PosterREPRINT AN LC/MS ORTHOGONAL TOF (TIME OF FLIGHT) MASS SPECTROMETER WITH INCREASED TRANSMISSION, RESOLUTION, AND DYNAMIC RANGE OVERVIEW OVERVIEW Exact mass LC/MS analysis using an orthogonal acceleration time of flight (oa-tof) mass spectrometer is a well-established technique with a broad range of applications. These include elemental

More information

GENERAL UNKNOWN SCREENING FOR DRUGS IN BIOLOGICAL SAMPLES BY LC/MS Luc Humbert1, Michel Lhermitte 1, Frederic Grisel 2 1

GENERAL UNKNOWN SCREENING FOR DRUGS IN BIOLOGICAL SAMPLES BY LC/MS Luc Humbert1, Michel Lhermitte 1, Frederic Grisel 2 1 GENERAL UNKNOWN SCREENING FOR DRUGS IN BIOLOGICAL SAMPLES BY LC/MS Luc Humbert, Michel Lhermitte, Frederic Grisel Laboratoire de Toxicologie & Génopathologie, CHRU Lille, France Waters Corporation, Guyancourt,

More information

Thermo Scientific SIEVE Software for Differential Expression Analysis

Thermo Scientific SIEVE Software for Differential Expression Analysis m a s s s p e c t r o m e t r y Thermo Scientific SIEVE Software for Differential Expression Analysis Automated, label-free, semi-quantitative analysis of proteins, peptides, and metabolites based on comparisons

More information

Pesticide Analysis by Mass Spectrometry

Pesticide Analysis by Mass Spectrometry Pesticide Analysis by Mass Spectrometry Purpose: The purpose of this assignment is to introduce concepts of mass spectrometry (MS) as they pertain to the qualitative and quantitative analysis of organochlorine

More information

The Use of Micro Flow LC Coupled to MS/MS in Veterinary Drug Residue Analysis

The Use of Micro Flow LC Coupled to MS/MS in Veterinary Drug Residue Analysis The Use of Micro Flow LC Coupled to MS/MS in Veterinary Drug Residue Analysis Stephen Lock AB SCIEX Warrington (UK) Overview A rapid, robust, sensitive and specific LC-MS/MS method has been developed for

More information

Lipid analysis by multiple "omic" mass spectrometry platforms Where we ve been, where we are, and where we re going

Lipid analysis by multiple omic mass spectrometry platforms Where we ve been, where we are, and where we re going Lipid analysis by multiple "omic" mass spectrometry platforms Where we ve been, where we are, and where we re going Jeff McDonald Department of Molecular Genetics UT Southwestern Medical Center Dallas,

More information

# LCMS-35 esquire series. Application of LC/APCI Ion Trap Tandem Mass Spectrometry for the Multiresidue Analysis of Pesticides in Water

# LCMS-35 esquire series. Application of LC/APCI Ion Trap Tandem Mass Spectrometry for the Multiresidue Analysis of Pesticides in Water Application Notes # LCMS-35 esquire series Application of LC/APCI Ion Trap Tandem Mass Spectrometry for the Multiresidue Analysis of Pesticides in Water An LC-APCI-MS/MS method using an ion trap system

More information

ProteinPilot Report for ProteinPilot Software

ProteinPilot Report for ProteinPilot Software ProteinPilot Report for ProteinPilot Software Detailed Analysis of Protein Identification / Quantitation Results Automatically Sean L Seymour, Christie Hunter SCIEX, USA Pow erful mass spectrometers like

More information

Thermo Scientific PepFinder Software A New Paradigm for Peptide Mapping

Thermo Scientific PepFinder Software A New Paradigm for Peptide Mapping Thermo Scientific PepFinder Software A New Paradigm for Peptide Mapping For Conclusive Characterization of Biologics Deep Protein Characterization Is Crucial Pharmaceuticals have historically been small

More information

Automation of Solid Phase Extraction and Column Chromatographic Cleanup

Automation of Solid Phase Extraction and Column Chromatographic Cleanup Automation of Solid Phase Extraction and Column Chromatographic Cleanup Haibin Wan Ltd. Problems with Manual Operation 1. Unstable flow rate affects reproducibility and throughput. 2. Not convenient for

More information

Rapid and Reproducible Amino Acid Analysis of Physiological Fluids for Clinical Research Using LC/MS/MS with the atraq Kit

Rapid and Reproducible Amino Acid Analysis of Physiological Fluids for Clinical Research Using LC/MS/MS with the atraq Kit Rapid and Reproducible Amino Acid Analysis of Physiological Fluids for Clinical Research Using LC/MS/MS with the atraq Kit Fast, simple and cost effective analysis Many areas of biochemical research and

More information

Aiping Lu. Key Laboratory of System Biology Chinese Academic Society APLV@sibs.ac.cn

Aiping Lu. Key Laboratory of System Biology Chinese Academic Society APLV@sibs.ac.cn Aiping Lu Key Laboratory of System Biology Chinese Academic Society APLV@sibs.ac.cn Proteome and Proteomics PROTEin complement expressed by genome Marc Wilkins Electrophoresis. 1995. 16(7):1090-4. proteomics

More information

C146-E087F. GCMS-QP2010 Plus. Shimadzu Gas Chromatograph Mass Spectrometer

C146-E087F. GCMS-QP2010 Plus. Shimadzu Gas Chromatograph Mass Spectrometer C146-E087F GCMS-QP2010 Plus Shimadzu Gas Chromatograph Mass Spectrometer The performance you have been waiting for is here. GCMS-QP2010 Plus GCMS-QP2010 Plus Shimadzu Gas Chromatograph Mass Spectrometer

More information

aurora M90 Innovation with Integrity A new era in ICP-MS ICP-MS

aurora M90 Innovation with Integrity A new era in ICP-MS ICP-MS aurora M90 A new era in ICP-MS Innovation with Integrity ICP-MS Your Partner in ICP-MS Solutions Bruker continues to find new and novel ways to meet your changing needs. As a leader in elemental analysis

More information

ProteinScape. Innovation with Integrity. Proteomics Data Analysis & Management. Mass Spectrometry

ProteinScape. Innovation with Integrity. Proteomics Data Analysis & Management. Mass Spectrometry ProteinScape Proteomics Data Analysis & Management Innovation with Integrity Mass Spectrometry ProteinScape a Virtual Environment for Successful Proteomics To overcome the growing complexity of proteomics

More information

Analysis of Polyphenols in Fruit Juices Using ACQUITY UPLC H-Class with UV and MS Detection

Analysis of Polyphenols in Fruit Juices Using ACQUITY UPLC H-Class with UV and MS Detection Analysis of Polyphenols in Fruit Juices Using ACQUITY UPLC H-Class with UV and MS Detection Evelyn Goh, Antonietta Gledhill Waters Pacific, Singapore, Waters Corporation, Manchester, UK A P P L I C AT

More information

QGA Quantitative Gas Analyser

QGA Quantitative Gas Analyser QGA Quantitative Gas Analyser A compact bench-top system for real-time gas and vapour analysis Detailed product information / introduction catalysis studies environmental gas analysis fermentation off-gas

More information

LC/MS/MS VARIAN, INC. 325-MS TRIPLE QUADRUPOLE MASS SPECTROMETER.

LC/MS/MS VARIAN, INC. 325-MS TRIPLE QUADRUPOLE MASS SPECTROMETER. LC/MS/MS VARIAN, INC. 325-MS TRIPLE QUADRUPOLE MASS SPECTROMETER www.varianinc.com VARIAN, INC. Small Molecules Big Challenges Your samples are precious and turnaround times are critical to the success

More information

Industry Perspective: Advantages of Open Access and Walkup LC/ MS Supporting Protein Drug Discovery and Development

Industry Perspective: Advantages of Open Access and Walkup LC/ MS Supporting Protein Drug Discovery and Development Industry Perspective: Advantages of Open Access and Walkup LC/ MS Supporting Protein Drug Discovery and Development Dawn Stickle, Agilent Technologies Originally presented by Eric Fang, Novartis Overview

More information

Application Note. Abstract. Author. Forensic and Toxicology

Application Note. Abstract. Author. Forensic and Toxicology An Application Kit for the Screening of Samples for Analytes of Forensic and Toxicological Interest using LC/QQQ MS/MS with a Dynamic MRM Transition Database Application Note Forensic and Toxicology Author

More information

Integrated Data Mining Strategy for Effective Metabolomic Data Analysis

Integrated Data Mining Strategy for Effective Metabolomic Data Analysis The First International Symposium on Optimization and Systems Biology (OSB 07) Beijing, China, August 8 10, 2007 Copyright 2007 ORSC & APORC pp. 45 51 Integrated Data Mining Strategy for Effective Metabolomic

More information

Pep-Miner: A Novel Technology for Mass Spectrometry-Based Proteomics

Pep-Miner: A Novel Technology for Mass Spectrometry-Based Proteomics Pep-Miner: A Novel Technology for Mass Spectrometry-Based Proteomics Ilan Beer Haifa Research Lab Dec 10, 2002 Pep-Miner s Location in the Life Sciences World The post-genome era - the age of proteome

More information

2016 Edition United States and Canada AGILENT UNIVERSITY COURSE CATALOG

2016 Edition United States and Canada AGILENT UNIVERSITY COURSE CATALOG 2016 Edition United States and Canada AGILENT UNIVERSITY COURSE CATALOG Agilent University A Complete Curriculum of Flexible Learning Solutions Welcome to Agilent University! Develop skills and improve

More information

Daniel M. Mueller, Katharina M. Rentsch Institut für Klinische Chemie, Universitätsspital Zürich, CH-8091 Zürich, Schweiz

Daniel M. Mueller, Katharina M. Rentsch Institut für Klinische Chemie, Universitätsspital Zürich, CH-8091 Zürich, Schweiz Toxichem Krimtech 211;78(Special Issue):324 Online extraction LC-MS n method for the detection of drugs in urine, serum and heparinized plasma Daniel M. Mueller, Katharina M. Rentsch Institut für Klinische

More information

Analysis of the Vitamin B Complex in Infant Formula Samples by LC-MS/MS

Analysis of the Vitamin B Complex in Infant Formula Samples by LC-MS/MS Analysis of the Vitamin B Complex in Infant Formula Samples by LC-MS/MS Stephen Lock 1 and Matthew Noestheden 2 1 AB SCIEX Warrington, Cheshire (UK), 2 AB SCIEX Concord, Ontario (Canada) Overview A rapid,

More information

Guide to Reverse Phase SpinColumns Chromatography for Sample Prep

Guide to Reverse Phase SpinColumns Chromatography for Sample Prep Guide to Reverse Phase SpinColumns Chromatography for Sample Prep www.harvardapparatus.com Contents Introduction...2-3 Modes of Separation...4-6 Spin Column Efficiency...7-8 Fast Protein Analysis...9 Specifications...10

More information