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1 Supplementary appendix This appendix formed part of the original submission and has been peer reviewed. We post it as supplied by the authors. Supplement to: Thiele H, Zeymer U, Neumann F-J, et al, on behalf of the Intraaortic Balloon Pump in cardiogenic shock II (IABP-SHOCK II) trial investigators. Intra-aortic balloon counterpulsation in acute myocardial infarction complicated by cardiogenic shock (IABP-SHOCK II): final 12 month results of a randomised, open-label trial. Lancet 2013; published online Sept 3.
2 Web appendix Time-to-Event Curves through 12 Months for All-cause Mortality for the As Treated Analysis Time-to-event curves through 12 months for all-cause mortality for the as treated analysis. The as treated analysis included all patients who crossed over in both directions which also includes those with immediate death in the catheterisation laboratory. P-values are based on the log-rank test. Event rates represent Kaplan- Meier estimates. 1
3 IABP-SHOCK II trial group and investigators Steering Committee: Holger Thiele (principal investigator and chair), University of Leipzig Heart Center, Leipzig, Germany; Gerhard Schuler, University of Leipzig Heart Center, Leipzig, Germany; Karl Werdan, Martin-Luther University of Halle-Wittenberg, Halle (Saale), Germany; Uwe Zeymer, Klinikum Ludwigshafen and Institut für Herzinfarktforschung, Ludwigshafen, Germany. Clinical Endpoints Committee: Holger Thiele, University of Leipzig Heart Center, Leipzig, Germany; Uwe Zeymer, Klinikum Ludwigshafen and Institut für Herzinfarktforschung, Ludwigshafen, Germany. Data Monitoring: Institut für Herzinfarktforschung, Ludwigshafen, Germany: Karin Vonderschmitt (chair); Sonja Frey; Beate Messemer. Data Management: Institut für Herzinfarktforschung, Ludwigshafen, Germany: Zehra Alkisoglu; Karin Vonderschmitt. Data Coordination and Analysis: Institut für Herzinfarktforschung, Ludwigshafen, Germany: Steffen Schneider (chair statistics); Taoufik Ourrak (statistics). Data Safety Monitoring Board: Johannes Haerting, PhD (chair and statistician), Martin- Luther-University Halle-Wittenberg, Halle (Saale), Germany, Germany; Kurt Huber, MD, Wilhelminenspital, Vienna, Austria; Bernhard Maisch, MD, University Hospital Giessen and Marburg, Marburg, Germany; Ferenc Follath, MD, University of Zurich, Zurich, Switzerland. Study sites and hospitals: University of Leipzig Heart Center, Leipzig, Germany: Holger Thiele, Steffen Desch, Georg Fuernau, Gerhard Schuler, Anja Leuschner, Suzanne de Waha, Ingo Eitel, Sabrina Wetzel, Tom Pausewang: 218 patients and 66 registry patients; Heart Center Bad Krozingen, Bad Krozingen, Germany: Franz-Josef Neumann, Miroslaw Ferenc: 50 patients and 0 registry patients; Asklepios Klinik Langen, Langen, Germany: Hans-Gerd Olbrich, Hans-Bernd Hopf: 42 patients and 18 registry patients; German Heart Center Munich, Munich, Germany: Jörg Hausleiter, Antoinette de Waha, Martin Orban, Carsten Lennerz, Melchior Seyfarth: 36 patients and 4 registry patients; Heart Center - Segeberger Kliniken, Bad Segeberg, Germany: Gert Richardt, Bettina Schwarz, Mohamed Abdel-Wahab, Ralph Toelg, Volker Geist, Monika Bahnsen-Maaß: 29 patients and 8 registry patients; SLK Kliniken Heilbronn, Heilbronn, Germany: Marcus Hennersdorf, Jochen Graf, Urs Riemann, Andreas Kuhn, Dominik Scharpf: 28 patients and 3 registry patients; University of Greifswald, Greifswald, Germany: Klaus Empen, Stephan B. Felix; Mathias C. Busch; Astrid Hummel; Thorsten Reffelmann: 19 patients and 12 registry patients; Martin-Luther-University Halle- Wittenberg, Halle (Saale), Germany: Karl Werdan, Henning Ebelt, Michael Buerke, Axel 2
4 Schlitt: 18 patients and 8 registry patients; Klinikum Links der Weser, Bremen, Germany: Rainer Hambrecht, Andreas Fach, Eduard Fiehn: 16 patients and 1 registry patient; Heart Center Ludwigshafen, Ludwigshafen, Germany: Uwe Zeymer, Anselm K. Gitt, Bernd Mark, Ralph Winkler: 14 patients and 9 registry patients; Zentralklinik Bad Berka, Bad Berka, Germany: Bernward Lauer, Jörg Fuhrmann: 13 patients and 11 registry patients; University Clinic of Saarland, Homburg/Saar, Germany: Michael Böhm, Andreas Link: 13 patients and 0 registry patients; Friedrich-Schiller University Jena, Jena, Germany: Hans-Reiner Figulla, Markus Ferrari, Christian Jung, Stephan Utschig: 11 patients and 14 registry patients; University of Lübeck, Lübeck, Germany: Volkhard Kurowski, Sebastian Wolfrum, Peter W. Radke, Heribert Schunkert: 11 patients and 2 registry patients; Klinik Hennigsdorf, Hennigsdorf, Germany: Hans-Heinrich Minden: 10 patients and 0 registry patients; Otto-von- Guericke-University Magdeburg: Rüdiger C. Braun-Dullaeus, Alexander Schmeißer, Friederike Walz: 9 patients and 3 registry patients; Sana Heart Center Cottbus, Cottbus, Germany: Jürgen Krülls-Münch, Kristin Rochor: 8 patients and 1 registry patient; Heart Center Dresden, Dresden, Germany: Ruth H. Strasser, Gregor Simonis: 8 patients and 0 registry patients; University of Würzburg, Würzburg, Germany: Sebastian Maier, Georg Ertl: 6 patients and 0 registry patients; Hospital München Neuperlach: Harald Mudra, Martin Hug: 5 patients and 9 registry patients; Krankenhaus der Barmherzigen Brüder, Regensburg, Germany: Peter Sick, Peter Bomba: 4 patients and 1 registry patient; Charité Berlin Campus Benjamin Franklin, Berlin, Germany: Hans-Peter Schultheiss, Carsten Tschöpe: 4 patients and 3 registry patients; Vivantes Klinikum am Urban, Berlin, Germany: Dietrich Andresen, Harry Roth: 4 patients and 0 registry patients; Carl-Thiem-Klinikum Cottbus, Cottbus, Germany: Jürgen Krülls-Münch, Christian Kurek: 3 patients and 1 registry patient; University Rostock: Christoph Nienaber, Hüseyin Ince, Hendrick Schneider: 3 patients and 6 registry patients; Kerckhoff Klinik Bad Nauheim, Bad Nauheim, Germany: Christian Hamm, Helge Möllmann: 3 patients and 0 registry patients; Helios Klinikum Erfurt, Erfurt, Germany: Harald Lapp: 3 patients and 0 registry patients; Charité Berlin - Campus Mitte, Berlin, Germany: Gert Baumann, Fabian Knebel: 2 patients and 1 registry patient; Ludwigs-Maximilian University Munich Hospital Großhadern: Wolfgang Franz: 2 patients and 0 registry patients; Vivantes Auguste-Viktoria-Klinikum, Berlin, Germany: Helmut Schühlen, Lars U. Stracke: 2 patients and 0 registry patients; Klinikum Weiden, Weiden, Germany: Robert H. Schwinger, Herrmann Bäuml: 2 patients and 0 registry patients; Klinikum Fulda, Fulda, Germany: Volker Schächinger: 1 patient and 0 registry patients; Katharinenhospital Unna, Unna, Germany: Daniel Gießmann: 1 patient and 0 registry patients; Philippusstift Essen, Essen, Germany: 3
5 Michael Lichtenberg: n=1 patient and n=1 registry patient; Carl-von-Basedow-Klinikum Merseburg, Merseburg, Germany: Roland Prondzinsky: 1 patient and 0 registry patients; Klinikum Lippe-Detmold, Detmold, Germany: Ulrich Tebbe: 0 patients and 5 registry patients; Schwarzwald-Baar Klinikum Villingen-Schwenningen, Villingen-Schwenningen, Germany; Ralf Birkemeyer: 0 patients and 3 registry patients. 4
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