NCCN TRENDS DEMOGRAPHICS. Results: December 2013 ORAL CANCER AGENTS. Distribution of Respondent Types (n = 780) 15% 68% 4% Page 1

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1 NCCN TRENDS Results: December 2013 NCCN Trends is an analytics tool from the National Comprehensive Cancer Network (NCCN ) that surveys how clinicians across the U.S. and around the globe are delivering cancer care. This summary includes the results of the December 2013 NCCN Trends Survey, which focused on Oral Cancer Agents. This survey was sent to U.S. and International users of NCCN.org. DEMOGRAPHICS Distribution of Respondent Types (n = 780) 15% Physician/Surgeon/Oncologist Nurse/Oncology Nurse or Clinical Nurse Specialist 8% Pharmacist 68% 4% 5% Physician Assistant or Nurse Practitioner Other Clinician Note: Percentages may not total 100 because of rounding. Page 1

2 Q1. Where are your patients receiving their oral cancer agents? (select all that apply) (n = 731) Specialty Pharmacy 78% Office Dispensing 22% Mail Order Retail Network 15% 14% 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% Page 2

3 Q1. Where are your patients receiving their oral cancer agents? (select all that apply) By Geography US Midwest US Northeast US South US West Europe Latin America Asia Other Non-US Specialty Pharmacy (n=571) 8% 10% 11% 2 1 Office Dispensing (n=158) 11% 7% 8% 30% 20% 4% Mail Order (n=108) 20% 1 33% 1 5% 2% Retail Network (n=100) 15% 11% 21% 11% 2% 22% Page 3

4 Q1. Where are your patients receiving their oral cancer agents? (select all that apply) By Practice Size 1 to 3 4 to 9 10 or more Specialty Pharmacy (n=571) 22% 23% 55% Office Dispensing (n=158) 20% 20% 60% Mail Order (n=108) 24% 1 5 Retail Network (n=100) 23% 24% 53% Page 4

5 Q1. Where are your patients receiving their oral cancer agents? (select all that apply) By Practice Setting Academic Setting Community Setting Specialty Pharmacy (n=562) 5 44% Office Dispensing (n=158) 52% 48% Mail Order (n=106) 45% 55% Retail Network (n=99) 48% 52% Page 5

6 Q1. Where are your patients receiving their oral cancer agents? (select all that apply) By Specialty Medical Oncology Radiation Oncology Surgical Oncology Internal Medicine General Surgery Other Specialty Pharmacy (n=571) 4 7% 5% 1% 14% Office Dispensing (n=158) 43% 7% 11% 3% 17% Mail Order (n=108) 5 7% 4% 8% 15% Retail Network (n=100) 50% 10% 1% Page 6

7 Q2. To your knowledge, how often are your patients able to meet their financial obligations (co-pays, co-insurance) tied to their oral cancer agents? (n = 712) > 75% 3 50% 28% 25% < 25% 23% 0% 10% 20% 30% 40% Page 7

8 Q2. To your knowledge, how often are your patients able to meet their financial obligations (co-pays, co-insurance) tied to their oral cancer agents? By Geography > 75% 50% 25% < 25% US Midwest (n=64) 22% 45% 22% 11% US Northeast (n=62) 34% 44% 1 US South (n=81) 31% 38% 17% 14% US West (n=43) 35% 37% 1 Europe (n=195) 48% 18% 28% Latin America (n=79) 28% 1 13% 43% Asia (n=131) 27% 27% 15% 31% Other Non-US (n=57) 60% 2 5% Page 8

9 Q2. To your knowledge, how often are your patients able to meet their financial obligations (co-pays, co-insurance) tied to their oral cancer agents? By Practice Size > 75% 50% 25% < 25% 1 to 3 (n=160) 33% 28% 13% 28% 4 to 9 (n=149) 40% 30% 21% 10 or more (n=403) 37% 28% 13% 22% Page 9

10 Q2. To your knowledge, how often are your patients able to meet their financial obligations (co-pays, co-insurance) tied to their oral cancer agents? By Practice Setting > 75% 50% 25% < 25% Academic Setting (n=385) 37% 2 10% 23% Community Setting (n=318) 35% 27% 14% 23% Page 10

11 Q2. To your knowledge, how often are your patients able to meet their financial obligations (co-pays, co-insurance) tied to their oral cancer agents? By Specialty > 75% 50% 25% < 25% Medical Oncology (n=343) 35% 31% 13% 21% Radiation Oncology (n=57) 40% 30% 7% 23% Surgical Oncology (n=90) 37% 27% 24% Internal Medicine (n=37) 41% 32% 1 8% General Surgery (n=10) 10% 20% 10% 60% Other (n=175) 38% 24% 10% 27% Page 11

12 NCCN TRENDS Results: December 2013 NCCN Trends is an analytics tool from the National Comprehensive Cancer Network (NCCN ) that surveys how clinicians across the U.S. and around the globe are delivering cancer care. NCCN Trends surveys are designed to reach targeted populations that can include several thousand clinicians as a potential sample size. NCCN can also provide analytics on existing NCCN Trends and clinician demographic data sets, allowing for greater insight into oncology practice patterns. To commission an NCCN Trends survey, to discuss analytic and data services, or to request information on other NCCN programs and resources, please contact: Christine MacCracken, MSHEd, BSN Senior Director, Business Insights maccracken@nccn.org National Comprehensive Cancer Network (NCCN ) The National Comprehensive Cancer Network (NCCN ), a not-for-profit alliance of 25 of the worldês leading cancer centers devoted to patient care, research, and education, is dedicated to improving the quality, effectiveness, and efficiency of cancer care so that patients can live better lives. Through the leadership and expertise of clinical professionals at NCCN Member Institutions, NCCN develops resources that present valuable information to the numerous stakeholders in the health care delivery system. As the arbiter of high-quality cancer care, NCCN promotes the importance of continuous quality improvement and recognizes the significance of creating clinical practice guidelines appropriate for use by patients, clinicians, and other health care decision-makers. 275 Commerce Drive Suite 300 Fort Washington, PA, Telephone: Fax: NCCN.org - For Clinicians NCCN.org/patients - For Patients * All NCCN Trends survey content and resulting data are owned by NCCN. Survey responses are made anonymous to protect the privacy of survey respondents. NCCN may license survey content, data, and analytic results to third parties, but retains the rights to use this data for other purposes, including the support of educational and research efforts or for other strategic or business purposes. Complex C-N Page 12