Careers in the Pharmaceutical Industry - what really counts - Dr. Wolfgang Haupt Novartis Vaccines & Diagnostics, Marburg, Germany

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1 Careers in the Pharmaceutical Industry - what really counts - Dr. Wolfgang Haupt Novartis Vaccines & Diagnostics, Marburg, Germany

2 Agenda Section 1 Overview on the Top Ten Pharmaceutical Companies Section 2 A few more words on Novartis Section 3 How a company functions Section 4 Career Opportunities for Bio- and Life Scientists Section 5 Career development opportunities Section 6 Key learning

3 in m US$ Total Revenue in m USD Overview on the Top Ten Pharmaceutical companies Total revenue and R&D expenses of the Top Ten Pharmaceutical Companies results Pfizer GSK Sanofi Av. Novartis Astra Zeneca J&J Merck Roche Eli Lilly Wyeth Total revenue R&D expenses 3 Careers in Industry / Career Workshop WH Jan 2010

4 What do they spend for Research & Development? 40% 2008 R&D expenses as % of total revenue Roche 35% 30% 25% 20% Merck Novartis 15% Sanofi Aventis GSK 10% Series1 Vaccine manufacturers Series2 in m US $ Pharma 4 Careers in Industry / Career Workshop WH Jan 2010

5 Agenda Section 1 Overview on the Top Ten Pharmaceutical Companies Section 2 A few more words on Novartis Section 3 How a company functions Section 4 Career Opportunities for Bio- and Life Scientists Section 5 Career development opportunities Section 6 Key learning

6 Novartis Research & Development A global network of center of competences UK La Jolla Genomics Gastro-intestinal diseases Respiratory diseases Basel Biomedical Research Epigenetics China Viral Cancers USA Cardiovascular diseases Diabetes & other metabolic dis. Infectious diseases Oncology Ophthalmology Corporate Research (non-profit oriented research) Switzerland Neurology Muscle-skeleton diseases Gastro-intestinal diseases Oncology Transplantation Dermatology Siena Vaccines research for neglected infectious diseases Singapur Tropical infectious diseases 6 Careers in Industry / Career Workshop WH Jan 2010

7 Novartis Institute for Biomedical Research (NIBR) Transforming drug discovery World-class research organization with about scientists globally Unique research strategy driven by patient needs Focus on the biological and molecular pathways shared by various diseases Cambridge global NIBR headquarters Integration of clinical insights with mechanistic understanding of disease should result in finding a molecular target structure Research-to-Development transition redefined through fast and rigorous proof-of-concept trials Strategic alliances with academia and biotech 7 Careers in Industry / Career Workshop WH Jan 2010

8 Fortune World s Most Admired Companies Novartis named #2 in pharmaceutical industry #1 Pfizer J&J J&J J&J Novartis J&J J&J #2 BMS Pfizer Novartis Novartis J&J Novartis Novartis #3 J&J Eli Lilly Eli Lilly Abbott Roche Merck Abbott #4 Merck Merck Abbott Amgen Eli Lilly Abbott Merck #5 Eli Lilly Novartis Pfizer GSK GSK Eli Lilly GSK #6 GSK GSK GSK Eli Lilly Amgen GSK Amgen #7 Novartis Abbott Amgen Roche Abbott Roche AstraZ #8 Pharmac. AstraZ Roche AstraZ Wyeth Amgen Eli Lilly #9 Wyeth Roche AstraZ Wyeth SanofiA Wyeth Wyeth #10 Aventis Aventis Wyeth Pfizer AstraZ AstraZ Boehr.Ing Rating Careers in Industry / Career Workshop WH Jan 2010

9 The Scientist Best Places To Work for Postdocs Novartis ranked #7 among top ten international institutions 9 Careers in Industry / Career Workshop WH Jan 2010

10 The Scientist Best Places To Work Novartis ranked #7 among top large companies 10 Careers in Industry / Career Workshop WH Jan 2010

11 Agenda Section 1 Overview on the Top Ten Pharmaceutical Companies Section 2 A few more words on Novartis Section 3 How a company functions Section 4 Career Opportunities for Bio- and Life Scientists Section 5 Career development opportunities Section 6 Key learning

12 How does a company function? First of all: You must have a good, if not the best product in the market! At least the product must have a competitive advantage. The 3 Basic Strategies to build Competitive Advantages Product Differentiation Service Differentiation Price Differentiation Advantage by Clear Focus Product Technology Leadership Competence Leadership Overall Cost Leadership Process Technology Leadership Many forms of focussing: - Geographic markets - Market segments -Buyer groups -Product lines - etc. Source: Michael E. Porter, Competitive Advantage 12 Careers in Industry / Career Workshop WH Jan 2010

13 Cost Structure Biopharmaceutical Industry Successful Biopharmaceuticals invest up to 50% of their revenues in R&D and S&M To be able to cover this future investments and to achieve a minimum target income of 10% the G&A and COGs expenditures are limited to a maximum of 40%. 100% 50% 20 25% 5 10% G&A 0thers <1% 10 45% COGs 10 20% Target Operating Income I&T Net Income 20 25% R&D S&M I&T = Interests and Taxes COGS = Cost of goods (manufacturing costs) G&A = General and Administrative costs S&M = Sales and Marketing R&D = Research and Development Source: Mercer Management Consulting; GAVI report Careers in Industry / Career Workshop WH Jan 2010

14 3 How a company is structured Strategic Processes Develop Vision & Strategy, e.g. the Strategic Plan Develop objectives, outputs and outcomes, e.g. Business Planning, Annual objectives Develop structure, processes and resource needs, e.g. Project Portfolio Management, Capital Investment Decisions Franchise Life Cycle Management or Disease Area Planning Alliance Management / Business Development Monitor, review and adapt all of the above Development to Launch Research & Preclinical Development Strategic Marketing Project Management Process &Tech Development Clinical Development RA Submission / Dossier Management Business Enabling Pre- Launch (support processes) Demand and Supply Production and Logistic Planning Technical Services (engineering, maintenance, validation) Industrializations / Design and build or upgrade platforms for new products Quality Assurance / Total Quality Management Regulatory Affairs Pharmaco-vigilance Business Intelligence HR Management IT Management Finance & Reporting Legal Procurement General Site Services HSE & BCM Design & build Quality Control / Quality Operations for new products Corporate Communications & Public Affairs Procurement Primary and Secondary Manufacturing QC, Batch review and Release (QA) Demand Management Shipping and Transportati on Selling Operational Marketing Customer Relationship Management Customer Service Tender management Medical / Scientific support Sales Product Communications & Public Affairs 14 Careers in Industry / Career Workshop WH Jan 2010

15 Agenda Section 1 Overview on the Top Ten Pharmaceutical Companies Section 2 A few more words on Novartis Section 3 How a company functions Section 4 Career Opportunities for Bio- and Life Scientists Section 5 Career development opportunities Section 6 Key learning

16 3 Which functions need Bio- or life scientists? Strategic Processes Develop Vision & Strategy, e.g. the Strategic Plan Develop objectives, outputs and outcomes, e.g. Business Planning, Annual objectives Develop structure, processes and resource needs, e.g. Project Portfolio Management, Capital Investment Decisions Franchise Life Cycle Management or Disease Area Planning Alliance Management / Business Development Monitor, review and adapt all of the above Development to Launch Research & Preclinical Development Strategic Marketing Project Management Process &Tech Development Clinical Development RA Submission / Dossier Management Pre- Launch Demand and Supply Production and Logistic Planning Procurement Primary and Secondary Manufacturin g Technical Services (engineering, maintenance, validation) Industrializations / Design and build or upgrade platforms for new products Design & build Quality Control / Quality Operations for new products QC, Batch review and Release Demand Management Shipping and Transportati on Selling Operational Marketing Customer Relationship Management Customer Service Tender management Medical / Scientific support Sales Product Communications & Public Affairs Business Enabling Quality Assurance / Total Quality Management Regulatory Affairs Pharmaco-vigilance Business Intelligence HR Management IT Management Finance & Reporting Legal Procurement General Site Services HSE & BCM Corporate Communications & Public Affairs (support processes) Direct needs 16 Careers in Industry / Career Workshop WH Jan 2010

17 3 Which functions need Bio- or life scientists? Strategic Processes Develop Vision & Strategy, e.g. the Strategic Plan Develop objectives, outputs and outcomes, e.g. Business Planning, Annual objectives Develop structure, processes and resource needs, e.g. Project Portfolio Management, Capital Investment Decisions Franchise Life Cycle Management or Disease Area Planning Alliance Management / Business Development Monitor, review and adapt all of the above Development to Launch Research & Preclinical Development Strategic Marketing Project Management Process &Tech Development Clinical Development RA Submission / Dossier Management Pre- Launch Demand and Supply Production and Logistic Planning Procurement Primary and Secondary Manufacturin g Technical Services (engineering, maintenance, validation) Industrializations / Design and build or upgrade platforms for new products Design & build Quality Control / Quality Operations for new products QC, Batch review and Release Demand Management Shipping and Transportati on Selling Operational Marketing Customer Relationship Management Customer Service Tender management Medical / Scientific support Sales Product Communications & Public Affairs Business Enabling Quality Assurance / Total Quality Management Regulatory Affairs Pharmaco-vigilance Business Intelligence HR Management IT Management Finance & Reporting Legal Procurement General Site Services HSE & BCM Corporate Communications & Public Affairs (support processes) Direct needs Indirect needs, for people with broader qualification 17 Careers in Industry / Career Workshop WH Jan 2010

18 Agenda Section 1 Overview on the Top Ten Pharmaceutical Companies Section 2 A few more words on Novartis Section 3 How a company functions Section 4 Career Opportunities for Bio- and Life Scientists Section 5 Career development opportunities Section 6 Key learning

19 Career development opportunities over the years You influence it / However, others will influence it as well CEO / COO level in USD m Vice President Executive Management level Exec. Director Senior Management level Manager Group Manager Senior Manager Director Management level Expert / Specialist level Careers in Industry / Career Workshop WH Jan 2010 years

20 Agenda Section 1 Overview on the Top Ten Pharmaceutical Companies Section 2 A few more words on Novartis Section 3 How a company functions Section 4 Career Opportunities for Bio- and Life Scientists Section 5 Career development opportunities Section 6 Key learning

21 Key Learning from working globally in a large enterprise There is no linear development of your career Be prepared for Ups and Downs Globalization drives everything Be flexible, look for opportunities to work abroad Always be clear about the price you are willing to pay Each country has its own management style Some are closer to your heart than others Business is getting faster every year Modern technology allows you to work everywhere, every time Find a work life balance Hierarchy levels are flattened Working in or leading a team is becoming more essential Substantial changes every two three years Offering uncertainties and chances 21 Careers in Industry / Career Workshop WH Jan 2010

22 What really counts! Performance Your Profile (education, languages, your special skills, your personality, social competence) Broaden your portfolio and knowledge, especially in management, economics and marketing Leadership Bite & Resilience Team work, communication and presentation skills Networking Strategic thinking in business and in planning and managing your career 22 Careers in Industry / Career Workshop WH Jan 2010

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