Combining Optogenetics with Electrophysiology Measurements

Size: px
Start display at page:

Download "Combining Optogenetics with Electrophysiology Measurements"

Transcription

1 Combining Optogenetics with Electrophysiology Measurements This research was supported by the National Institute of Aging of the National Institutes of Health under award number R44AG The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

2 Pinnacle s Optogenetic System A turn-key optogenetics system with integrated biopotential/neurotransmitter recordings for mice and rats. LED fiber probes deliver > 100 mw/mm 2 for most wavelengths 445, 515, 590, 640 & 660 nm. No optical commutator is required. The system has precision timing, TTL inputs/ outputs and multiple head stage configurations (opto only, sleep + opto, seizure + opto, biosensor + opto, sleep or seizure + biosensor + opto, etc.) The next few slides will illustrate in vivo data available from this system for EEG and biosensors

3 Methods Transgenic mice [(Thy1-COP4/EYFP) 9Gfng - Jackson Laboratory] (n=4) expressing channelrhodopsin (activated by blue light) in the hippocampus and cortex and wild-type C57 mice (n=4) were used. All mice were implanted with a cannula and depth electrode targeting the hippocampus, and two cortical electrodes. In a subset of mice (n=2), a second cannula was placed in the anterior cortex. All procedures were approved by the University of Kansas IACUC. After 1 week, a blue 445 nm LED fiber probe was inserted in the hippocampal guide cannula and optical stimulations were performed. Next, the probe was replaced with a deep red 660 nm probe and the experiment repeated. In mice with a second cannula, a glutamate biosensor was inserted ~12 h prior to optogenetic stimulation. Light was delivered for either 20 seconds (EEG) or 40 seconds (EEG + biosensor) at an intensity > 100 mw/mm2 at 20 Hz, 10% duty cycle. Five to ten trials were conducted on each animal with 10 minutes between stimulation trials.

4 Stimulation Induces Seizure Activity In Transgenic Mice EEG activity during and after stimulation with blue (445 nm) and deep red (660 nm) light in the same animal. Stimulation parameters: 20 Hz, 5 ms 20 s (10% duty cycle) 600 ma LED probe intensity Blue: 130 mw/mm 2 Deep red : 155 mw/mm Seconds

5 Stimulation Does Not Induce Seizure in Wild-Type Mice 20 Seconds EEG activity during and after stimulation with blue (445 nm) light in a wild-type C57 mouse. Light pulses were delivered at 20 Hz, 5 ms duration (10% duty cycle) for 20 seconds with a current of 600mA. Blue LED intensity was measured prior to implantation at 100 mw/mm 2. No response or artifact was seen in any of the control mice (n=4).

6 Stimulation Induces Glutamate Change in Transgenic Mice Average change in extracellular glutamate concentration in the frontal cortex during a single 40 s stimulation (20 Hz, 10% duty cycle, 600 ma) with blue (445 nm) and deep red (660 nm) light in the same animal (n=5). Representative EEG depth electrode activity is plotted during time of stimulation. Bars represent S.E.M.

7 Considerations when Integrating Optogenetics and Recording Systems Merge Optogenetics with other measurements (EEG, EMG, FSCV, Biosensors, Microdialysis ). Add very tight timing and control for light delivery. Ensure that the systems are synchronized. Possibly merge multiple software packages. Provide a method for feedback (i.e. when a seizure is detected, trigger optical stimulation). And put this all on the head of a freely moving mouse/rat in a way that does not alter behavior, neurochemistry or physiology.

8 Pinnacle s Solution A turn-key system that can be readily used by any researcher. Move the LED to the head of the animal, so no optical commutator is needed.

9 Core System The key component of the Pinnacle system is the Optogenetics Interface Module which provides precise timing and illumination control when used with our existing 3- and 4-channel data acquisition systems. This unit connects to an electrical commutator and headstage. The system uses LED fiber probes which are compatible with standard cannula placement techniques and do not require an optical commutator. Nine headstages are available for mice or rats.

10 Pinnacle s LED Fiber Probes

11 Opsins and LEDs

12 Heating Impact of LED Probes

13 One More Tool to Make Your Research Easier An LED Probe with a Depth Electrode Tip detail with depth electrode next to optical fiber

Manipulating and probing nerve cells by light. PhD Arto Lipponen Depart. of psychology

Manipulating and probing nerve cells by light. PhD Arto Lipponen Depart. of psychology Manipulating and probing nerve cells by light PhD Arto Lipponen Depart. of psychology Presentation PART 1 (theory) - Manipulating and probing techniques Optogenetics - manipulating and probing nerve cells

More information

LLS Series LED Light Sources Installation and Operation Instructions

LLS Series LED Light Sources Installation and Operation Instructions LLS Series LED Light Sources Installation and Operation Instructions Description Ocean Optics LED Series light sources (LLS) are engineered to be a versatile tool for scientific and general lighting applications.

More information

Portable in vivo Recording System

Portable in vivo Recording System Portable in vivo Recording System 16 or 32 channel version Pre- and filter amplifier included USB 2.0 data transfer Adapters for commercially available probes Real-time signal detection and feedback The

More information

Fiber Optic Distributed Temperature Sensor (B-DTS)

Fiber Optic Distributed Temperature Sensor (B-DTS) Fiber Optic Distributed Temperature Sensor (B-DTS) Low-cost Brillouin BOTDA scattering version For more information about our strain and temperature sensor system and related products, please visit www.ozoptics.com

More information

EXHIBIT C BOSTON SCIENTIFIC PRODUCTS AVAILABLE FOR NIH BRAIN INITIATIVE Page 1 of 9

EXHIBIT C BOSTON SCIENTIFIC PRODUCTS AVAILABLE FOR NIH BRAIN INITIATIVE Page 1 of 9 Page 1 of 9 NOTE: All systems and products should be considered as investigational-use only in the context of the NIH BRAIN Initiative. VERCISE DEEP BRAIN STIMULATION SYSTEM Description: 16-channel rechargeable

More information

Investigating the Neurophysiological Effects of Direct Current Stimulation. Joaquin de Rojas Steven Siegel Roy Hamilton

Investigating the Neurophysiological Effects of Direct Current Stimulation. Joaquin de Rojas Steven Siegel Roy Hamilton Investigating the Neurophysiological Effects of Direct Current Stimulation Joaquin de Rojas Steven Siegel Roy Hamilton Doing summer research 1. Define area of interest Interface of Cognitive Neurology

More information

user manual Manual Part No

user manual Manual Part No user manual Manual Part No. 502408 Index 1.0 Introduction..........................2 This Manual...........................2 2.0 Safety Summary......................3 Terms in this Manual....................3

More information

Powerful advances in whole-field electrophysiology measurements

Powerful advances in whole-field electrophysiology measurements Powerful advances in whole-field electrophysiology measurements Introducing Advanced electrophysiology focused on your research needs. Phoenix Research Labs electrophysiology tools are not adaptations

More information

What We Have Learned From Intracranial Direct Electrical Stimulation (SEEG Studies)

What We Have Learned From Intracranial Direct Electrical Stimulation (SEEG Studies) What We Have Learned From Intracranial Direct Electrical Stimulation (SEEG Studies) Cristi Donos 1, Andrei Barborica 1,5, Ioana Mindruta 2,3, Jean Ciurea 4, Alin Rasina 4, Bogdan Balanescu 1,4 1 Physics

More information

Laser Diode Controller LDC1000

Laser Diode Controller LDC1000 Laser Diode Controller LDC1000 Features Applications Laser Diode Driver High power laser diode control Up to 300, 600 or 1.500W Pumping solid state and fiber lasers Up to 150A laser diode current Material

More information

Type-D EEG System for Regular EEG Clinic

Type-D EEG System for Regular EEG Clinic Type-D EEG System for Regular EEG Clinic Type-D EEG amplifier Specifications 1. For Type-D Amplifier Input channels: 12/24/36/48 Monopolar EEG + 12channels Bipolar EEG+12 channels PSG. Power supply: Internal

More information

RESTORATION OF RESPIRATORY MOTOR FUNCTION THROUGH OPTOGENETIC NEURAL IMPLANTS

RESTORATION OF RESPIRATORY MOTOR FUNCTION THROUGH OPTOGENETIC NEURAL IMPLANTS RESTORATION OF RESPIRATORY MOTOR FUNCTION THROUGH OPTOGENETIC NEURAL IMPLANTS Ivo Lieberam, United Kingdom Grant: 80 000 Most higher animals that live on land, including humans, breathe air through their

More information

Sophisticated Life Science Research Instrumentation. Vogel Test System. Anxiety Monitoring System

Sophisticated Life Science Research Instrumentation. Vogel Test System. Anxiety Monitoring System Sophisticated Life Science Research Instrumentation Vogel Test System Anxiety Monitoring System www.tse-systems.com Info@TSE-Systems.com Specifications subject to change without notice TSE Vogel Test System

More information

The physiological background of EMG

The physiological background of EMG The physiological background of EMG Lida Mademli Centre of Research & Technology - Hellas Informatics & Telematics Institute Definition of EMG Electromyography: The discipline that deals with the detection,

More information

9.0 Components Description. 10.0 SENTIO MMG System Quick Setup. 10.1 Plugging in Control Unit. 10.2 Attaching Sensor Harness

9.0 Components Description. 10.0 SENTIO MMG System Quick Setup. 10.1 Plugging in Control Unit. 10.2 Attaching Sensor Harness 9.0 Components Description The main components of the SENTIO MMG System consist of the SENTIO MMG Control Unit with preinstalled SENTIO MMG Software and the SENTIO MMG Sensor Harness. The SENTIO MMG Control

More information

Neuro imaging: looking with lasers in the brain

Neuro imaging: looking with lasers in the brain Neuro imaging: looking with lasers in the brain Aim: To image life cells, label free, with cellular resolution in deep tissue Marloes Groot Vrije Universiteit Amsterdam Faculteit Exacte Wetenschappen Natuurkunde

More information

2 Neurons. 4 The Brain: Cortex

2 Neurons. 4 The Brain: Cortex 1 Neuroscience 2 Neurons output integration axon cell body, membrane potential Frontal planning control auditory episodes soma motor Temporal Parietal action language objects space vision Occipital inputs

More information

WaveReady CFM. Optical Link Monitoring System: Continuous Fiber Monitor

WaveReady CFM. Optical Link Monitoring System: Continuous Fiber Monitor WaveReady CFM Optical Link Monitoring System: Continuous Fiber Monitor www.lumentum.com Data Sheet The Lumentum Continuous Fiber Monitor (CFM) offers a compact, modular solution for performance monitoring

More information

Theta, Gamma, and Working Memory

Theta, Gamma, and Working Memory Theta, Gamma, and Working Memory Lecture 3.8 David S. Touretzky November, 2015 Outline Theta rhythm and gamma rhythms Phase precession in hippocampus Theta and gamma in entorhinal cortex Lisman working

More information

Using the NI 17xx Smart Camera Direct Drive Lighting Controller

Using the NI 17xx Smart Camera Direct Drive Lighting Controller Using the NI 17xx Smart Camera Direct Drive Lighting Controller Overview The use of proper lighting is often overlooked when designing a machine vision application. More robust and accurate inspections

More information

Measuring Laser Power and Energy Output

Measuring Laser Power and Energy Output Measuring Laser Power and Energy Output Introduction The most fundamental method of checking the performance of a laser is to measure its power or energy output. Laser output directly affects a laser s

More information

CFMRI Physiological Monitoring System. Operator s Manual

CFMRI Physiological Monitoring System. Operator s Manual CFMRI Physiological Monitoring System Operator s Manual This manual provides a quick guidance to using the physiological monitoring system during an MRI session. It is not intended as a substitute for

More information

NetScanner System. Toronto: 416 754 7008, Montreal: 514 695 5147, Toll Free:1888 754 7008, Email: sales@a-tech.ca; www.a-tech.ca

NetScanner System. Toronto: 416 754 7008, Montreal: 514 695 5147, Toll Free:1888 754 7008, Email: sales@a-tech.ca; www.a-tech.ca Networking Solutions NetScanner System 9IFC/90DB/90DC FEATURES Ethernet Interface for NetScanner System Modules Provides Power and Hardware Trigger Interface 10/100 Base-T Auto-Negotiating Universal AC

More information

Overview of Modulated and Pulsed Diode Laser Systems

Overview of Modulated and Pulsed Diode Laser Systems 1 Overview of Modulated and Pulsed Diode Laser Systems Contents 1 Introduction 2 2 Pulsed Lasers 2 2.1 Peak Power................................................... 2 2.2 Average Power..................................................

More information

Basic Architecture of the Visual Cortex. A.L. Yuille (UCLA)

Basic Architecture of the Visual Cortex. A.L. Yuille (UCLA) Basic Architecture of the Visual Cortex A.L. Yuille (UCLA) The Retina and the Cortex. Basic Biology. With about 10 million retinal receptors, the human retina makes on the order of 10 to 100 million measurements

More information

PRODUCT SHEET OUT1 SPECIFICATIONS

PRODUCT SHEET OUT1 SPECIFICATIONS OUT SERIES Headphones OUT2 BNC Output Adapter OUT1 High Fidelity Headphones OUT1A Ultra-Wide Frequency Response Headphones OUT3 see Stimulators OUT100 Monaural Headphone 40HP Monaural Headphones OUT101

More information

SpectraTec II. Polarized Multi-Laser Source BLUE SKY RESEARCH WAVELENGTHS. The SpectraTec II

SpectraTec II. Polarized Multi-Laser Source BLUE SKY RESEARCH WAVELENGTHS. The SpectraTec II BLUE SKY RESEARCH The SpectraTec II, two wavelength laser module is a highly integrated system comprised of two lasers, individual driving and temperature control electronics, wavelength combining, and

More information

MEASURING BRAIN CHANGES IN HEARING LOSS AND ITS REMEDIATION

MEASURING BRAIN CHANGES IN HEARING LOSS AND ITS REMEDIATION MEASURING BRAIN CHANGES IN HEARING LOSS AND ITS REMEDIATION Blake W Johnson 1,3, Stephen Crain 2,3 1 Department of Cognitive Science, Macquarie University 2 Department of Linguistics, Macquarie University

More information

APPLICATION NOTES: Dimming InGaN LED

APPLICATION NOTES: Dimming InGaN LED APPLICATION NOTES: Dimming InGaN LED Introduction: Indium gallium nitride (InGaN, In x Ga 1-x N) is a semiconductor material made of a mixture of gallium nitride (GaN) and indium nitride (InN). Indium

More information

Welcome to this presentation on Thermal Characteristics of LEDs, part of OSRAM Opto Semiconductors LED Fundamentals series.

Welcome to this presentation on Thermal Characteristics of LEDs, part of OSRAM Opto Semiconductors LED Fundamentals series. Welcome to this presentation on Thermal Characteristics of LEDs, part of OSRAM Opto Semiconductors LED Fundamentals series. In this presentation we will look at the basics of thermal management in LED

More information

Trigno/Vicon System Integration

Trigno/Vicon System Integration Delsys and Vicon Analog Integration Motion capture systems will often have the ability to sample analog data channels as a convenient means for synchronizing external data streams with motion capture data.

More information

Particle Time of Flight: Reflections on Gas Flow Measurement in Hazardous Environments

Particle Time of Flight: Reflections on Gas Flow Measurement in Hazardous Environments 1 Abstract The goal of this project was to create precise optical flow meters for the oil & gas industry optimized for measuring flare gas flow in explosive atmospheres. The flow meters had to incorporate

More information

Laboratory Guide. Anatomy and Physiology

Laboratory Guide. Anatomy and Physiology Laboratory Guide Anatomy and Physiology TBME04, Fall 2010 Name: Passed: Last updated 2010-08-13 Department of Biomedical Engineering Linköpings Universitet Introduction This laboratory session is intended

More information

Microvitae présente 4 communications à l'e-mrs, 14-17 mai 2012, Strasbourg

Microvitae présente 4 communications à l'e-mrs, 14-17 mai 2012, Strasbourg Microvitae présente 4 communications à l'e-mrs, 14-17 mai 2012, Strasbourg Lundi 14 mai 2012 09:30 In vivo cortical and hippocampal activity recordings by using high-resolution plastic electrode arrays

More information

(USB-) ME-Systems Manual

(USB-) ME-Systems Manual (USB-) ME-Systems Manual Information in this document is subject to change without notice. No part of this document may be reproduced or transmitted without the express written permission of Multi Channel

More information

ZEISS T-SCAN Automated / COMET Automated 3D Digitizing - Laserscanning / Fringe Projection Automated solutions for efficient 3D data capture

ZEISS T-SCAN Automated / COMET Automated 3D Digitizing - Laserscanning / Fringe Projection Automated solutions for efficient 3D data capture ZEISS T-SCAN Automated / COMET Automated 3D Digitizing - Laserscanning / Fringe Projection Automated solutions for efficient 3D data capture ZEISS 3D Digitizing Automated solutions for efficient 3D data

More information

Information in this document is subject to change without notice.

Information in this document is subject to change without notice. MC_Rack Manual Information in this document is subject to change without notice. No part of this document may be reproduced or transmitted without the express written permission of Multi Channel Systems

More information

Precise Timing & Synchronization

Precise Timing & Synchronization Precise Timing & Synchronization Stable Clocks - Accurate Triggers - High Resolution Pulses Precise Timing and Synchronization at some level is required in most Automatic Test Equipment (ATE), Data Acquisition

More information

CRT Color Sensors, LRT Luminescence Scanners, KRT Contrast Scanners Extensive family of scanners for a wide range of detection tasks

CRT Color Sensors, LRT Luminescence Scanners, KRT Contrast Scanners Extensive family of scanners for a wide range of detection tasks CRT Color Sensors, LRT Luminescence Scanners, KRT Contrast Scanners Extensive family of scanners for a wide range of detection tasks PRODUCT INFORMATION Color? Luminescence? Contrast? Everything from a

More information

Beta-TX Laser Diode Module. T he Beta-TX is a complete self contained laser diode system

Beta-TX Laser Diode Module. T he Beta-TX is a complete self contained laser diode system Laser Diode Module A HIGH SPEED MODULATABLE LASER WITH SPEEDS UP TO 50 MHZ Features Modulation speeds up to 50 MHz Visible and Infra red versions Powers from 1mW to 100 mw Flexible design accommodating

More information

1 Synchronising Xsens Systems with Noraxon TeleMyo

1 Synchronising Xsens Systems with Noraxon TeleMyo 1 Synchronising Xsens Systems with Noraxon TeleMyo The steps described below show how to make it possible for Xsens Awinda or Sync Station to send a signal (Awinda / Sync Station is Sync OUT and Noraxon

More information

Selecting Philips XP 2972 Photomultiplier Tubes for the Electron Muon Ranger (EMR)

Selecting Philips XP 2972 Photomultiplier Tubes for the Electron Muon Ranger (EMR) MICE-NOTE-DET-383 Selecting Philips XP 2972 Photomultiplier Tubes for the Electron Muon Ranger (EMR) Ruslan Asfandiyarov, Alain Blondel, Dasom Lee, Daniel Lievens DPNC, University of Geneva, Switzerland

More information

Using Brainmaster Discovery & Atlantis devices with OpenViBE

Using Brainmaster Discovery & Atlantis devices with OpenViBE Using Brainmaster Discovery & Atlantis devices with OpenViBE The Brainmaster Discovery and Atlantis driver of the OpenViBE acquisition server is dedicated to Brainmaster devices. These devices have been

More information

CONTENTS Processors... 4 Front Ends... 6 Cables...10 Adapters...11 Trellis Software Suite...14 Applications...16 Contact Information...

CONTENTS Processors... 4 Front Ends... 6 Cables...10 Adapters...11 Trellis Software Suite...14 Applications...16 Contact Information... Welcome to the, a hardware and software platform for neuroscience research and neuroprosthesis development. Our systems are compact, portable, and optimized for real-time, high-channel-count, closed-loop

More information

Short Pulsed & Ultrafast Laser Applications for Enhanced Fuel Economy

Short Pulsed & Ultrafast Laser Applications for Enhanced Fuel Economy Short Pulsed & Ultrafast Laser Applications for Enhanced Fuel Economy Lasers in Automotive Technical Symposium September 19, 2013 Sascha Weiler TRUMPF Inc., Farmington CT The Power of Choice for Laser

More information

DRTS 33. The new generation of advanced test equipments for Relays, Energy meters, Transducers and Power quality meters

DRTS 33. The new generation of advanced test equipments for Relays, Energy meters, Transducers and Power quality meters The new generation of advanced test equipments for Relays, Energy meters, Transducers and Power quality meters Testing all relay technologies: electromechanical, solid state, numerical and IEC61850 Manual

More information

Radiofrequency Ablation

Radiofrequency Ablation Radiofrequency Ablation Product Guide n LeVeen Needle Electrodes n LeVeen SuperSlim Needle Electrodes n LeVeen CoAccess Electrode System n Soloist Single Needle Electrodes n RF 3000 Radiofrequency Generator

More information

OPERATING INSTRUCTIONS AND SYSTEM DESCRIPTION FOR THE EXT 10-2F EXTRACELLULAR AMPLIFIER / FILTER MODULE FOR EPMS SYSTEMS

OPERATING INSTRUCTIONS AND SYSTEM DESCRIPTION FOR THE EXT 10-2F EXTRACELLULAR AMPLIFIER / FILTER MODULE FOR EPMS SYSTEMS OPERATING INSTRUCTIONS AND SYSTEM DESCRIPTION FOR THE EXT 10-2F EXTRACELLULAR AMPLIFIER / FILTER MODULE FOR EPMS SYSTEMS VERSION 2.8 npi 2015 npi electronic GmbH, Bauhofring 16, D-71732 Tamm, Germany Phone

More information

Rapid Eye Movement Detection using Support Vector Machine. Cristian H. Díaz, Leonardo A. Causa, Javier J. Causa and Claudio M.

Rapid Eye Movement Detection using Support Vector Machine. Cristian H. Díaz, Leonardo A. Causa, Javier J. Causa and Claudio M. Rapid Eye Movement Detection using Support Vector Machine Cristian H. Díaz, Leonardo A. Causa, Javier J. Causa and Claudio M. Held INTRODUCTION Sleep states and stages are identified by the presence of

More information

Optical and RF transparent long-term biocompatible micro-packages

Optical and RF transparent long-term biocompatible micro-packages Optical and RF transparent long-term biocompatible micro-packages Rony Jose James, Guido Spinola Durante, Mark Fretz, Ch. Bosshard, Stefan Mohrdiek Alpnach, 08.06.2015 Agenda General overview (photonics)

More information

2 General Application Photoelectric Sensors

2 General Application Photoelectric Sensors General Purpose Photoelectric Sensor 2 General Application Photoelectric Sensors CLASSIC 2-25 General Application Photoelectric Sensors 2 Since introducing the SMARTEYE line, these unique pulse modulated

More information

Instructions for Setting the T560 Digital Delay Generator for the Target Delay

Instructions for Setting the T560 Digital Delay Generator for the Target Delay Instructions for Setting the T560 Digital Delay Generator for the Target Delay Important! These instructions are only to be followed by beam-line operators who have been trained to operate the target!!

More information

HLC2701 Encoder Detector

HLC2701 Encoder Detector HLC2701 FEATURES Side-looking plastic package TTL/LSTTL/CMOS compatible Inverting logic output Linear or rotary encoder applications Resolution to 0.009 in.(.229 mm) Sensitivity versus temperature compensation

More information

The Detection of Neural Fatigue during intensive conditioning for football: The Potential of Transcranial Magnetic Stimulation

The Detection of Neural Fatigue during intensive conditioning for football: The Potential of Transcranial Magnetic Stimulation The Detection of Neural Fatigue during intensive conditioning for football: The Potential of Transcranial Magnetic Stimulation Carl Wells PhD Sport Science Lead, Perform, National Football Centre, St.

More information

Experiment 5. Lasers and laser mode structure

Experiment 5. Lasers and laser mode structure Northeastern University, PHYS5318 Spring 2014, 1 1. Introduction Experiment 5. Lasers and laser mode structure The laser is a very important optical tool that has found widespread use in science and industry,

More information

Resonance and the Speed of Sound

Resonance and the Speed of Sound Name: Partner(s): Date: Resonance and the Speed of Sound 1. Purpose Sound is a common type of mechanical wave that can be heard but not seen. In today s lab, you will investigate the nature of sound waves

More information

OFI-200 Optical Fiber Identifier

OFI-200 Optical Fiber Identifier OFI-200 Optical Fiber Identifier Quick Reference Guide The OFI-200 is powered by a standard 9 volt alkaline battery that typically provides over 10,000 operations. Power is controlled by the clamping trigger

More information

NRSN Summer School in Neuroscience 2016: Neural Circuits and Behavior

NRSN Summer School in Neuroscience 2016: Neural Circuits and Behavior NRSN Summer School in Neuroscience 2016: Neural Circuits and Behavior Kavli Institute of Systems Neuroscience, NTNU, Trondheim 21-28 August 2016 Summary: Understanding the brain or the theory of mind has

More information

EMG Biofeedback Device

EMG Biofeedback Device EMG Biofeedback Device Nu-Tek Maxi Plus 1 Model no: LE1000 Single channel EMG biofeedback device for the measurement of muscle activity and muscle exercise. Highlights 2.4'' full Color dot matrix display

More information

PatchMAX 100A Ordering Information. Product Description. Specifications Major Components

PatchMAX 100A Ordering Information. Product Description. Specifications Major Components PatchMAX 100A Incredibly small footprint This patent-pending design has an 8" x 8" footprint; it is the smallest multifunction patch clamp system available. The automated patch clamping system replaces

More information

Building a Simulink model for real-time analysis V1.15.00. Copyright g.tec medical engineering GmbH

Building a Simulink model for real-time analysis V1.15.00. Copyright g.tec medical engineering GmbH g.tec medical engineering GmbH Sierningstrasse 14, A-4521 Schiedlberg Austria - Europe Tel.: (43)-7251-22240-0 Fax: (43)-7251-22240-39 office@gtec.at, http://www.gtec.at Building a Simulink model for real-time

More information

Product Introduction MyoMuscle. Telemyo DTS-System. Telemetry system for EMG and Biomechanical Sensors. www.noraxon.com

Product Introduction MyoMuscle. Telemyo DTS-System. Telemetry system for EMG and Biomechanical Sensors. www.noraxon.com Product Introduction MyoMuscle Telemyo DTS-System Telemetry system for EMG and Biomechanical Sensors DTS Device Family 3 major device categories can be used for the Direct Transmission System technology

More information

Classic EEG (ERPs)/ Advanced EEG. Quentin Noirhomme

Classic EEG (ERPs)/ Advanced EEG. Quentin Noirhomme Classic EEG (ERPs)/ Advanced EEG Quentin Noirhomme Outline Origins of MEEG Event related potentials Time frequency decomposition i Source reconstruction Before to start EEGlab Fieldtrip (included in spm)

More information

Topic 5: Measurement and Analysis of EMG Activity

Topic 5: Measurement and Analysis of EMG Activity Topic 5: Measurement and Analysis of EMG Activity Laboratory Manual Section 05 HPHE 6720 Dr. Cheatham What is Electromyography (EMG)? Electromyography (EMG) is an experimental technique concerned with

More information

DC Motor Driver 24V 20A [RKI-1340]

DC Motor Driver 24V 20A [RKI-1340] DC Motor Driver 24V 20A [RKI-1340] Users Manual Robokits India info@robokits.co.in http://www.robokitsworld.com Page 1 Add raw power and simple connectivity to your robotics applications with this 24V

More information

PSR-36_X User Manual

PSR-36_X User Manual PSR-36_X User Manual Powered Slip Ring Commutator For Maximum Subject Freedom of Movement Document Revision 1.00 Last Revised: December 11, 2007 Neuralynx, Inc. 4055 Valley Commons Dr Suite G, Bozeman,

More information

ibond5000 Ball Wire Bonder

ibond5000 Ball Wire Bonder ibond5000 Ball Wire Bonder Sample stage LCD interface Manual Z Mouse Work table Figure 1: ibond5000 Ball Bonder Introduction The ibond 5000 is a ball bonder for making electrical interconnections between

More information

SIU-102 Manual, Rev 050816. Warner Instruments 1125 Dixwell Avenue, Hamden, CT 06514 (800) 599-4203 / (203) 776-0664 (203) 776-1278 - fax

SIU-102 Manual, Rev 050816. Warner Instruments 1125 Dixwell Avenue, Hamden, CT 06514 (800) 599-4203 / (203) 776-0664 (203) 776-1278 - fax SIU-102 Manual, Rev 050816 Bipolar Stimulation Isolation Unit Model SIU-102 1125 Dixwell Avenue, Hamden, CT 06514 (800) 599-4203 / (203) 776-0664 (203) 776-1278 - fax SIU-102 Manual, Rev 050816 2 Table

More information

CLASS IV THERAPY LASERS

CLASS IV THERAPY LASERS CLASS IV THERAPY LASERS 80% More than 80% of your patients can benefit from K-Laser therapy. 970 - - - - - - - - - - - - - - - - - - - - - - - - - - - - - PEAK OF WATER 905 - - - - - - - - - - - - - -

More information

LASER MARKING SYSTEMS Integrated heads

LASER MARKING SYSTEMS Integrated heads LASER MARKING SYSTEMS Integrated heads LASER Laser RANGE i103 L-G n 10W n 20W n 50W Laser Technology LASER TECHNOLOGY: FAST AND HIGH QUALITY MARKING ON ALMOST ANY MATERIAL! INTÉGRABLES Component traceability

More information

Bioreactor Process Plant Powered by NI LabVIEW and NI CompactRIO

Bioreactor Process Plant Powered by NI LabVIEW and NI CompactRIO Bioreactor Process Plant Powered by NI LabVIEW and NI CompactRIO Segment: Industry Country: Singapore Author(s): Sanka Hettiarachchi, Providev Kevin Kho, Technologies Unlimited Products: NI crio-9075 (Integrated

More information

IDGH AMPLITUDE FRONTO-CENTRAL ALPHA AND THETA ACTIVITY DURING THE TRANSCENDENTAL MEDITATION TECHNIQUE

IDGH AMPLITUDE FRONTO-CENTRAL ALPHA AND THETA ACTIVITY DURING THE TRANSCENDENTAL MEDITATION TECHNIQUE PAPER 211 IDGH AMPLITUDE FRONTO-CENTRAL ALPHA AND THETA ACTIVITY DURING THE TRANSCENDENTAL MEDITATION TECHNIQUE ANNE-MARIE ROUZERE, KHEIREDDINE BADAWI, and RENATE HARTMANN Department of Neurophysiology,

More information

1100 Series. Xenon Flashlamps. Technologies are. over. Spectroradiometry. applications. Machine vision. High radiant intensity

1100 Series. Xenon Flashlamps. Technologies are. over. Spectroradiometry. applications. Machine vision.  High radiant intensity DATASHEET Lightingg Solutions High Stability Short Arc Xenon Flashlamps FX Flashlamps from Excelitas provide exceptional arc stability. Key Features Exceptional arc stability High radiant intensity Continuous

More information

QR12 (1.22 ) Diameter Optical Encoder

QR12 (1.22 ) Diameter Optical Encoder Improving the Quality of Life through the Power in Light QPhase QR12 (1.22 ) Diameter Optical Encoder Design Features: Low profile assembled height of Bearing design simplifies encoder attachment Resolutions

More information

Proposal for steps to be taken in the software development for CMS tracker sub structure tests W. Beaumont (Antwerpen) V.

Proposal for steps to be taken in the software development for CMS tracker sub structure tests W. Beaumont (Antwerpen) V. Proposal for steps to be taken in the software development for CMS tracker sub structure tests W. Beaumont (Antwerpen) V.Zhukov (Karlsruhe) software is important The software has a big influence on the

More information

K1- Fluo. Easy Operation Software The dedicated software controls confocal microscope with easy and intuitive user interface.

K1- Fluo. Easy Operation Software The dedicated software controls confocal microscope with easy and intuitive user interface. K1- Fluo K1-Fluo is confocal fluorescence laser scanning microscopy from Nanoscope Systems - developed for versatile biological, chemical, and medical purpose. Optimized system components ensure great

More information

Information in this document is subject to change without notice.

Information in this document is subject to change without notice. LTP-Director Manual Information in this document is subject to change without notice. No part of this document may be reproduced or transmitted without the express written permission of Multi Channel Systems

More information

Brain Computer Interfaces (BCI) Communication Training of brain activity

Brain Computer Interfaces (BCI) Communication Training of brain activity Brain Computer Interfaces (BCI) Communication Training of brain activity Brain Computer Interfaces (BCI) picture rights: Gerwin Schalk, Wadsworth Center, NY Components of a Brain Computer Interface Applications

More information

Smith & Nephew DYONICS RF Radiofrequency System

Smith & Nephew DYONICS RF Radiofrequency System I-1 Smith & Nephew DYONICS RF Radiofrequency System Smith & Nephew is proud to present a variety of RF options to meet the specialized needs of today s arthroscopist. The DYONICS RF Radiofrequency System

More information

Microreactor Chips. product datasheet

Microreactor Chips. product datasheet Unit 1, Anglian Business Park, Orchard Road, Royston, Hertfordshire, SG8 5TW, UK T: +44 (0)1763 242491 F: +44 (0)1763 246125 E: sales@dolomite-microfluidics.com W: www.dolomite-microfluidics.com Microreactor

More information

Spatially Resolved Recording of Fluorescence-Lifetime Transients by Line- Scanning TCSPC

Spatially Resolved Recording of Fluorescence-Lifetime Transients by Line- Scanning TCSPC Spatially Resolved Recording of Fluorescence-Lifetime Transients by Line- Scanning TCSPC Abstract: We present a technique that records transient effects in the fluorescence lifetime of a sample with spatial

More information

Using Flow Control with the HEAD Recorder

Using Flow Control with the HEAD Recorder 03/15 Using with the HEAD Recorder The HEAD Recorder is a data acquisition software program that features an editable Flow Control function. This function allows complex program sequences to be predefined,

More information

NeXus: Event-Related potentials Evoked potentials for Psychophysiology & Neuroscience

NeXus: Event-Related potentials Evoked potentials for Psychophysiology & Neuroscience NeXus: Event-Related potentials Evoked potentials for Psychophysiology & Neuroscience This NeXus white paper has been created to educate and inform the reader about the Event Related Potentials (ERP) and

More information

COULBOURN HUMAN MEASUREMENT SYSTEM SCRIPT-DRIVEN IMAGERY SOFTWARE FOR THE PORTABLE PHYSIOLOGY PLATFORM USERS GUIDE (HMS-300-P3)

COULBOURN HUMAN MEASUREMENT SYSTEM SCRIPT-DRIVEN IMAGERY SOFTWARE FOR THE PORTABLE PHYSIOLOGY PLATFORM USERS GUIDE (HMS-300-P3) COULBOURN HUMAN MEASUREMENT SYSTEM SCRIPT-DRIVEN IMAGERY SOFTWARE FOR THE PORTABLE PHYSIOLOGY PLATFORM USERS GUIDE (HMS-300-P3) Table of Contents Software Installation...1 Utilities... 1 Audition/Register

More information

ADC1000-USB A/D Converter Operating Instructions

ADC1000-USB A/D Converter Operating Instructions ADC1000-USB A/D Converter Operating Instructions Rev. 2.03 05062005 Offices: Ocean Optics, Inc. 830 Douglas Ave., Dunedin, FL, USA 34698 Phone 727.733.2447 Fax 727.733.3962 8:30 a.m.-6 p.m. EST Ocean Optics

More information

Histological Verification of Electrode Placement in Single Unit Recorded Rats

Histological Verification of Electrode Placement in Single Unit Recorded Rats University of Connecticut DigitalCommons@UConn Honors Scholar Theses Honors Scholar Program Spring 5-1-2016 Histological Verification of Electrode Placement in Single Unit Recorded Rats Dana Lew University

More information

LED Anti-Collision Lighting System for Airbus A320 Family

LED Anti-Collision Lighting System for Airbus A320 Family LED Anti-Collision Lighting System for Airbus A320 Family LEDs established in anti-collision lighting For the first time, UTC Aerospace Systems has implemented state-ofthe-art LED technology into an anti-collision

More information

«Bodescan» THE ULTIMATE 3D SCANNER FOR DATA ACQUISITION OF HUMAN BODY A COMPREHENSIVE SYSTEM INCLUDING HARDWARE AND SOFTWARE TOOLS

«Bodescan» THE ULTIMATE 3D SCANNER FOR DATA ACQUISITION OF HUMAN BODY A COMPREHENSIVE SYSTEM INCLUDING HARDWARE AND SOFTWARE TOOLS «Bodescan» THE ULTIMATE 3D SCANNER FOR DATA ACQUISITION OF HUMAN BODY A COMPREHENSIVE SYSTEM INCLUDING HARDWARE AND SOFTWARE TOOLS Page 2 of 9 Bodescan HUMAN BODY3D SCANNING HARDWARE AND SOFTWARE INCLUDED

More information

Nederland België / Belgique

Nederland België / Belgique Cronus Brochure 2 Introduction Cronus: The first spectrometer and colorimeter in one The Cronus is world s first spectrocolorimeter combining a high en VIS spectrometer with a high speed XYZ colorimeter.

More information

LNG Monitoring. Fiber-Optic Leakage Detection System. Pipeline leakage detection. Regasification and liquefaction monitoring

LNG Monitoring. Fiber-Optic Leakage Detection System. Pipeline leakage detection. Regasification and liquefaction monitoring LNG Monitoring Fiber-Optic Leakage Detection System Pipeline leakage detection Regasification and liquefaction monitoring Tank annulus and base slab monitoring Spill containment control Intelligent Solutions

More information

AC/DC Power Supply Reference Design. Advanced SMPS Applications using the dspic DSC SMPS Family

AC/DC Power Supply Reference Design. Advanced SMPS Applications using the dspic DSC SMPS Family AC/DC Power Supply Reference Design Advanced SMPS Applications using the dspic DSC SMPS Family dspic30f SMPS Family Excellent for Digital Power Conversion Internal hi-res PWM Internal high speed ADC Internal

More information

REMOTE MONITORING AND CONTROL SYSTEM

REMOTE MONITORING AND CONTROL SYSTEM REMOTE MONITORING AND CONTROL SYSTEM The Comanche RMCS automatically monitors and controls digital and analog functions and processes associated with the oil and gas industries, which include but are not

More information

Fiber Optics. Integrated Photo Detector Receiver for Plastic Fiber Plastic Connector Housing SFH551/1-1 SFH551/1-1V

Fiber Optics. Integrated Photo Detector Receiver for Plastic Fiber Plastic Connector Housing SFH551/1-1 SFH551/1-1V Fiber Optics Integrated Photo Detector Receiver for Plastic Fiber Plastic Connector Housing SFH551/1-1 Features Bipolar IC with open-collector output Digital output, TTL compatible Sensitive in visible

More information

Page 2 CK K. Figure 3: JK Flip-flops with asynchronous PRESET and CLEAR inpu CK K. Figure 2: JK Flip-flops with different types of triggering

Page 2 CK K. Figure 3: JK Flip-flops with asynchronous PRESET and CLEAR inpu CK K. Figure 2: JK Flip-flops with different types of triggering EGR 78 Digital Logic Lab File: N78L9A Lab # 9 Multivibrators A. Objective The objective of this laboratory is to introduce the student to the use of bistable multivibrators (flip-flops), monostable multivibrators

More information

A system for optically controlling neural circuits with very high spatial and temporal resolution

A system for optically controlling neural circuits with very high spatial and temporal resolution A system for optically controlling neural circuits with very high spatial and temporal resolution Chethan Pandarinath, Eric T. Carlson, and Sheila Nirenberg Abstract Optogenetics offers a powerful new

More information

104 Practice Exam 2-3/21/02

104 Practice Exam 2-3/21/02 104 Practice Exam 2-3/21/02 1. Two electrons are located in a region of space where the magnetic field is zero. Electron A is at rest; and electron B is moving westward with a constant velocity. A non-zero

More information

Pulsed Laser Diode Module LS-Series

Pulsed Laser Diode Module LS-Series Pulsed Laser Diode Module LS-Series Description The LS-series of pulsed laser diode modules offer all of the features needed to safely drive pulsed lasers of different powers, in a compact housing. The

More information

Trigger Timing Controller

Trigger Timing Controller Trigger Timing Controller rev 1.01 October 29, 2009 Licel GmbH, Gustav-Meyer-Allee 25, 13355 Berlin, Germany Getting started 1 Overview The Trigger Timing controller is designed to meet typical lidar measurement

More information

MOTOR ALTERATIONS IN HEPATIC ENCEPHALOPATHY MECHANISMS AND TREATMENTS

MOTOR ALTERATIONS IN HEPATIC ENCEPHALOPATHY MECHANISMS AND TREATMENTS MOTOR ALTERATIONS IN HEPATIC ENCEPHALOPATHY MECHANISMS AND TREATMENTS Patients with liver disease show alterations in motor function and coordination including: psychomotor slowing, ataxia, flapping tremor,

More information

From Fresco, Ophthalmology, 1998

From Fresco, Ophthalmology, 1998 Phosphenes: Phosphenes are perceived flashes of light that arise because of internal activity in the retina or higher visual system. Phosphenes can be caused by mechanical action on the retina, as occurs

More information