Health and ICT research in the Ile-de-France Region. IWT Flanders, 8th December 2010
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1 Health and ICT research in the Ile-de-France Region IWT Flanders, 8th December 2010
2 Ile-de-France key figures 11.6 million inhabitants highest GDP among European regions: 553 billion second most popular location for the world s leading corporations jobs created by new foreign companies in companies (2008) business creation (2008): business closures (2008): jobs (2007) unemployment rate: 7,9 % (3rd trimester 2009) R&D 137,300 people working in R&D 3.1% of GDP spent on Research & Development 182 patents per million inhabitants 17 universities, covering all scientific and technical disciplines and about 50 Grandes Écoles Region s investment in R+I & HE: 220 million (2010)
3 LEADING MULTINATIONAL HEADQUARTERED OR LOCATED IN ILE-DE-FRANCE: Bio-Rad, CIS bio international, GE Medical Systems, Guerbet, Innothera Services, Servier, LFB, Philips Medical Systems France, Sanofi-Aventis, IPSEN, Siemens Medical Solutions France. I. R&D in the Health sector I. 1. Key Figures WORLD-CLASS RESEARCH INSTITUTIONS 300 public and private research laboratories 11,800 researchers including 4,400 in industry 50% of France s academic research and prestigious, world-renowned institutions: Pasteur, Curie and Gustave Roussy institutes, CNRS, INSERM, CEA, INRIA (National institute for research in computer science and control), INRA (National institute for agricultural research), etc. The AP-HP - Assistance Publique-Hôpitaux de Paris - Europe's largest hospital Network: 39 hospitals with a total capacity of around 23,000 beds. A HIGHLY QUALIFIED LABOUR POOL 65,000 skilled workers active in life sciences 9 universities and 20 Grandes écoles offering complete courses in medical and life sciences. Number of health related companies (2008): 320 pharmaceutical companies / 360 in the area of medical devices / 150 biotech companies
4 I. 2. Regional Bioparks 1. Biocitech: 8 hectares of real estate 28,500 square meters of office and lab space 24 companies, including 8 start-ups 2. Paris Biotech Santé: 3. Cancer Campus: 4. Genopole : 21 academic research labs, including the CEA Genomics Institute (which hosts the French national sequencing and genotyping centers) 70 life science companies 18 shared-access technical facilities and technology platforms 87,298 square meters of labs and office space I. 3. MEDICEN Paris Region
5 MEDICEN: THE CLUSTER S MISSION To maintain and reinforce the Paris IIe-de-France region as Europe s leading industrial center for diagnostic & therapeutic innovation and health technologies 5
6 MEDICEN S OBJECTIVES Catalyzing economic growth and employment in thriving markets by successfully interfacing start-ups/smes, multinationals, academic laboratories, hospitals, training organizations and healthcare providers and promoting technology transfer Reinforcing the international competitiveness of the healthcare and medtech sector by stimulating the region s innovative capacity Boosting the Paris region s attractiveness and dynamism 6
7 MEDICEN S R&D STRATEGY Catalyzing innovation transfer from research institutions to the industrial sector and reducing the time to market for therapeutic and/or technological innovations THE AIM IS Facilitating access to innovation Increasing the transfer of innovation from the research sector to the industrial sector Accelerating the marketing of therapeutic and/or technological innovations beneficial to patients 7
8 A R&D STRATEGY BASED ON 3 MAIN R&D AREAS Translational medicine (clinical research, medical imaging) to promote access to medical innovation Biological tools for industrial use and biotherapeutic products for better diagnosis, treatment and prognosis Biodigital technology: bio-computing, integration and modelling, e-health, brain-machine interface technology 3 KEY AREAS FOR THERAPEUTIC AND DIAGNOSTIC APPLICATIONS Cancers Neurodegenerative, sensory and psychiatric diseases Infectious diseases 8
9 AND A MULTIDISCIPLINARY APPROACH
10 MEDICEN MEMBERS AND PARTNERS (1) 150+ members and partners (June 2010): (1) small businesses and (2) large companies: 120 (3) research & academia: 23 (4) national, regional & local public authorities: 13.
11 MEDICEN MEMBERS AND PARTNERS (2)
12 More information on Cluster and project funding partners
13 I. 4. Other regional health R&D networks (1) 1. NEUROSCIENCES and NEURODEGENERATIVE DISEASES The NERF (Neuroscience pole for research in Ile-de-France) represents and brings together the different actors in this field. Main partner organisations: Institut de la Vision (Institute of vision) in the Quinze Vingts hospital Institut du Cerveau et de la Moelle épinière - ICM (Brain and spinal cord Institute) at the «Pitié-Sâlpetrière» hospital Institut du Fer à Moulin (Neurobiology), National Institute for Health and Medical Research (INSERM) ; St Anne Hospital (Psychatric and neuropathology research) «Pôle de longévité et du vieillissement» of the Charles Foix hospital, Gerontechnology (ageing research from a technical and scientific point of view) «Neurovalley» covering different projects in the health area (Kremlin-Bicêtre) including neurobiomedical imaging platforms (Neurospin, MIRCen, Service Hospitalier Frédéric Joliot of the French Atomic Energy Commission CEA) Website:
14 I. 4. Other regional health R&D networks (2) 2. CANCER: The Canceropôle coordinates the different actors in the field. Institut Curie Institut Gustave Roussy Institut Universitaire d Hématologie at the Saint Louis Hospital (Website: 3. CARDIOVASCULAR DISEASES, DIABETES, OBESITY: The network gathers the following institutions: Hôpital européen Georges Pompidou Centre de recherches Biomédicales des Cordelières Cochin hospital Lariboisière hospital Pitié-Salpétrière hospital Saint-Vincent-de-Paul hospital Henri Mondor hospital CRNH Centre de Recherche en Nutrition Humaine (Research centre for human nutrition) (Website:
15 I. 4. Other regional health R&D networks (3) 4. UPCOMING INFECTIOUS, PARASITIC AND NOSOCOMIAL DISEASES Under the coordination of the Pasteur Institute, it gathers: Pasteur Institute, and its Upcoming infectious diseases Institute Genoscope (sequencing projects of various infectious agents) L Institut Cochin CNRS Gif sur Yvette INRA Jouy-en-Josas (Website: 5. STEM CELLS AND MOLECULAR MEDICINE ( The StemPôle network gathers most of the Region s organisations active in the field of regeneration medicine: Necker Enfants malades hospital : biotherapy department, centre of clinical investigation Pitié-Sâlpetrière hospital: biotherapy platform the I-STEM : the Institute for stem cell therapy and exploration of monogenic diseases Henry Mondor hospital: biotherapy, cellular and genetic therapy, centre of clinical investigation Etablissement Français du Sang - EFS (French blood institute) Plate-forme de cellules souches (platform of stem cells) at the Paul Brousse Hospital
16 II. R&D in the ICT sector 18,000 researchers and engineers A large number of public and private-sector research laboratories (France Telecom R&D, Thomson, CEA (the atomic energy commission), INRIA (the national computing and systems science institute), LIP6 (University of Paris IV computing lab), Thales, Alcatel-Lucent, IRCAM (the acoustics and music research and coordination institute) and centres run by the CNRS. Presence of the main prime contractors in the different ICT segments: Software: Dassault Systems, Business Objects, etc. Telecommunications: Orange, Alcatel-Lucent, Siemens, Motorola, Huawei, ZTE, etc. Digital content: Thomson, Vivendi, Ubisoft, Lagardère, etc. Defence and security: Thales, Safran, Gemalto, etc. Optics: EADS, GE Healthcare, etc. Electronics: Sagem, Thales, Valeo, etc. Exponential growth of the IT sector in the region over the past few years: 3,900 start-up companies established in this sector in 2006, i.e. a 7% increase compared with Foreign direct investment (FDI)* in the IT sector in the region grew by 100% between 2004 and 2006.
17
18 II. R&D in the ICT sector II. 1. Paris Region: the regional cluster for embedded and complex systems
19 Applicative markets Technolo gies Systematic: Technologies & Markets Common vision: Digital Revolution for industry and services Systems OCDS Design Logiciel and Libre OptiqueFree Electronique and Open Development Tools Source Software Automotive & Transport Automobile & Transports Sécurité & Défense Security & Defense Télécoms Telecoms Outils de Conception et Développement de Systèmes Logiciels Libres ICT & Sustainable Cities ( Strategic Plan) ICT & Health ( Strategic Plan) 19 Systematic 2010
20 Automotive & Transport Working Group Electronic embedded systems in transport and safety Create a collaborative development platform for embedded software Algorithms / data fusion for localisation and vision Architectures Safety Function 52 TECHNO-PROVIDERS from the Paris- Region are involved in this field Funded Projects : 33 Man -machine interface Diagnostic Methods and tools Partners : 71 including 22 SMEs Development Axes Systematic 2010
21 Security & Defence Working Group Security of critical infrastructures : transportation, energy, decisionmaking centres, leisure sites... Security of information systems : e-gov, e-commerce, communication, digital ID Need to secure these systems = development challenges, addressing 2 fast growing markets Physical safety technologies Trusted digital systems 100 TECHNO-PROVIDERS in Paris-Region are involved in this field Funded Projects : 49 Goods and people security systems Security Technologies Partners : 144 including 45 SMEs Development Axes Systematic 2010
22 Telecom Working Group Develop and distribute services on broadband infrastructures and communication High speed networks 153 TECHNO-PROVIDERS in Paris-Region are involved in this field Wireless Connectivity Personalised Services & Communications Funded Projects : 53 Partners : 151 of which 86 SMEs Development Axes Systematic 2010
23 Systems Design & Development Tools Working Group Mastering development risks Multi-disciplinary simulation and optimisation tools Systems engineering to satisfy customer needs at lower cost Develop services software and platforms High performance computing 139 TECHNO-PROVIDERS in Paris-Region are involved in this field Modelling systems simulation Software engineering Funded Projects : 89 Partners : 224 including 113 SMEs Development Axes Systematic 2010
24 Free & Open Source Software Working Group Develop specific R&D projects in the field of Free Software Contribute to the development of the offer in the field of Free Software Develop the organisation of innovation coming from the end-users in the fied of Free Software Information Systems Funded Projects : 21 Technologies for free software infrastructure Development axes Technologies and tools for the development of Free and Open Source Software Partners : 90 members including 48 SMEs Systematic 2010
25 Some of the Systematic key players Automotive & Transport Working Group: ALSTOM TRANSPORT, ARMINES, CEA, CNRS, CONTINENTAL, DELPHI, FREESCALE, GEENSYS, INRETS, INRIA, INTEMPORA, RENAULT, VALEO, VISTEON Systems Design and Development Tools Working Group: EADS ASTRIUM, CEA, C-S, DASSAULT AVIATION, DISTENE, ECP, EDF, ESTEREL TECHNOLOGIES, FLOWMASTER, INRIA, SAMTECH, SPRING TECHNOLOGIES, THALES, UTC Security & Defence Working Group: ALCATEL-LUCENT, BULL, CEA, EADS, GEMALTO, HGH Systèmes Infrarouges, INRIA, MARTEC, ORANGE, SAGEM DEFENSE SECURITE, TELECOM & Management SudParis, THALES Telecoms Working Group: ALCATEL-LUCENT, CITY PASSENGER, CNRS / SUPELEC / LSS, EGIDE, FRANCE TELECOM, Université Paris-Sud 11 / IEF, INRIA FUTURS, TELECOM & Management SudParis, THALES Free & Open Source Software Working Group: CAP GEMINI, C-S, INRIA, MANDRIVA, NUXEO, Université Pierre et Marie Curie / LIP6, UNIVERSITE PARIS 7, BULL Systematic
26 In total more than 540 organisations involved in the R&D network of Systematic : 310 SMEs, 110 big companies, 90 research and HE organisations, 15 regional / local authorities Systematic R&D domains = jobs in private companies and jobs in public R&D in the region Systematic and its projects are supported by More information : 26
27 II. R&D in the ICT sector II. 2. Cap Digital: the regional cluster for digital content and services
28 Cap digital Business Cluster for Digital Content
29 Cap Digital: The French Business Cluster for Digital Content Accredited in 2005 with strong support from the French government Ile de France (Paris Region) is the first European region in ICT The Content industry represents +160,000 jobs 70-80% of the French digital market assesed at 12B 29
30 One Industrial Sector, Strategic Domains Communication Design Digital Lifestyle & Services Collaborative Technologies Audiovisual & New Media e-education and e-training Video Games Digital Economy Knowledge Engineering Content Cultural Heritage Knowledge Robotics
31 Cap Digital: over 330 members 20 major corporations Lagardère, France Télécom, Thomson, Thales, Motorola, Editis, Microsoft, UbiSoft, EDF, Alcatel, Bull 6 private sector groups Capital Game, FICAM, Pôle audiovisuel nord parisien, Silicon Sentier, Simavelec, SPFA 280+ SMEs 40 public bodies Universities, public research labs, and higher education establishments : 140 labs Public companies : IGN, INA, la Cité des Sciences Regional and County Councils 31 Réf
32 How we operate Stimulate innovation process Networking events : LA CANTINE Workshops, conferences web-site, newsletters Promote collaborative projects A label to support R&D funding Set-up open testbeds THD platform Provide services to members International Business relationship, funders (BAs, VCs) 32
33 The «cap digital» Projects (2008) 220+ R&D projects received in two years (320 today) 112 labeled and funded for a total budget of more than 275M including public funds of more than 115M 48% of public funds are given to SMEs 40% to Research Labs 150+ Cap Digital members are involved in R&D projects Ranked 4th for amount of R&D funding among the 71 French Business Clusters 33
34 More about Cap Digital The Cap Digital booklet Contacts: (0)
35 III. R&D in the ICT & Health sector III. 1. Opticsvalley
36 BIO & ICT topic at OPTICSVALLEY Opticsvalley A clusters that brings together the business community in the optics, electronics and software sectors. Regular meetings between companies and research laboratories lead to improved cooperation, detection of research and development projects, and support for SMEs. Bio & ICT the application of Information and Communication Technologies (optical, electronic and software technologies) in life science, medicine and health Bio & ICT focus within the cluster Biophotonic (applications of laser in medicine, medical imaging, ) E-health (Telemedecine, gerontechnologies, monitoring and treatment of chronic diseases for example). 36
37 TECHNOLOGIES & APPLICATIONS Our members perform leading edge research in areas such as: E-health : Medical devices for telemedicine applications. Wireless sensors and sensor networks for health state and wellness monitoring User-centered design of integrated ICT systems and services for elderly. Monitoring and treatment of chronic diseases (CVD, diabetes and age-related diseases). Architectural design, integration of living environments and technology Information processing, decision support Biophotonic : Laser OCT technology Surface Plasmon Resonance imaging (SPRi) in the life science Microarray instrumentation for diagnostic, clinical and life science research 37
38 SME Laser & components (Genewave, Genoptics, Quantel) Imaging (LLTech, Mauna Kea) Medical Systems (orfidée, SRETT) Resarch laboratories Ecole Centrale d Electronique, Laboratoire Charles Fabry, Laboratoire d Electronique et Electromagnétisme Institutions SOME PARTNERS AP-HP, Genopôle, Pôle de compétitivité Medicen Institut de la vision, Université Pierre Marie Curie 38
39 Le réseau optique, électronique et logiciel en Ile-de-France And much more to discover on Contacts: Cyril MOUSSANT / soutiennent Opticsvalley
40 III. R&D in the ICT & Health sector III. 2. Charles Foix Longevity Pole
41 Pôle Allongement de la Vie - Charles Foix / Ivry sur Seine (Charles Foix Longevity Pole) Innovation for increased autonomy of older and impaired people Vivre bien, plus longtemps 41
42 Pôle genesis Longevity is a real demographical «silent revolution» Complementary partners decided to join to answer this big issue «Live better, longer» Scientific, institutional, industrial partners together for this ambitious project A common and new ambition Built around Charles Foix hospital, important geriatric academic hospital (800 beds) Based in Ivry, near Paris, participate to the local dynamics of «Paris Biotech Valley» A partenarial and federative project, associating searchers, teachers, doctors and parameds, firms, local actors Vivre bien, plus longtemps 42
43 Cross fertilisation SCIENCE & MEDICINE EDUCATION & TRAINING GERONTECHNOLOGIES (INNOVATION, VALORISATION) AGE & SOCIETY Vivre bien, plus longtemps 43
44 Subject Existing In progress A terme SCIENCES & MEDICINE Charles Foix hospital Care & clinical research An europan reference Research and Development Center Opens in jan 2010 Longevity Insitute Translational Research Center (2012) Platform GERON- TECHNOLOGIE Charles Foix Research and Innovation Grant Gerontechnology competencies Network Charles Foix gérontechnologies Forum Research (robotics) Firms nursery biotechn. gerontech. + TRAINING Excellency in training Medical & scientific (geriatry, gerontology, Aging biology) Social sciences training Demonstration and Valuation Centre AGE & SOCIETY Social and citizenship innovation for elder people Conferences Vivre bien, plus longtemps Social innovation experimentations, etc. 44
45 Works in progress Short and mid-term projects Arising of the Longevity Institute Previsional opening in early 2010 Reinforcing the gerontechnology competence Development of the training part Developing partnership (France, international) Long term projects Realising the project of the plate-form Firm nursery (biotech.+ gerontech.) Demonstration and expertise center Developing social innovations / experimentations (best practices, recommendations, ) Vivre bien, plus longtemps 45
46 With the support of Vivre bien, plus longtemps 46
47 Pôle s members Local actors Codev Medical and research actors Fesio Charles Foix Vivre bien, plus longtemps 47
48 For more information Vivre bien, plus longtemps 48
49 Thank you for your attention Cédric Daumas Ile-de-France Europe 10 rue Montoyer B-1000 Bruxelles Tél: Fax:
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