Biomedicine The background. The main interest. The tools
|
|
|
- Morgan Turner
- 8 years ago
- Views:
Transcription
1 1
2 Biomedicine The background The main interest? Bioinformatics Clinical informatics The tools 2
3 Outline 3
4 Outline 4
5 Working on Network Data Analysis HH RR Infrastructure Training BIOCOMPUTATION & STRUCTURAL BIOLOGY PROGRAM BIOINFORMATICS UNIT Biological data Molecular Biology of Childhood Tumors FB CHUVI 5
6 CNIO Molecular Oncology (Dr. Maria Blasco) Structural Biology & Biocomputation (Dr. Alfonso Valencia) Molecular Pathology (Dr. M. A. Piris) Human Cancer Genetics (Dr. Javier Benítez) Experimental Therapies (Dr. James R. Bischoff) Biotechnology (Dr. Ignacio Casal) 6
7 Outline 7
8 CNIO Bioinformatics Unit & PDG Group. David Gonzalez. Pisano (Head) Eduardo Andrés (CNIO) Angel Carro (CNIO) Andrés Cañada (INB) Jose Maria Fdez.(UBio) Jaime Fdez. Vera (PDG) Gonzalo Gómez (CHUVI-INB) Osvaldo Graña (UBio) Jose Manuel Rodríguez. (INB) PDG Group 8
9 Bioinformatics Group. (FICHUVI - Universidade de Vigo) Enrique Caso (Head) Florentino Fdez. Riverola (Head) Gonzalo Gómez (Postdoc) Daniel Gonzalez (PhD Student) Pablo Vicente Carrera (Student) Alberto Molares (PhD Student) Carmen M. Redondo (Postdoc) 9
10 Outline 10
11 Research lines 11
12 Research lines. B-cell lymphomas functional analysis. Almost 200 B-cell lymphomas 8 clinical subtypes Clustering analysis 12
13 Research lines. B-cell lymphomas functional analysis. Gene Set Enrichment Analysis of NFKB pathway genes in Follicular and Burkitt Lymphomas using Biocarta annotations. Figure 1. Applying Kolmogorov-Smirnof test to find assymmetries in expression levels of functional related blocks of genes, NFKB pathway genes was found enriched in Follicular lymphomas in comparison to Burkitt lymphomas. Figure 2. Heatmap for expression values of those genes involved in NFKB pathway. Figure 3. Map of interactions for NFKB pathway related genes. Figure 3 Figure 1 Figure 2 13
14 Research lines. B-cell lymphomas transcriptome. Clustering the behaviour of whole pathways in B-cell lymphomas. 14
15 Research lines. Genetic Instability in Ewing Sarcomas. -Gene Set Enrichment Analysis of Cytobands and Pathways in Ewing Sarcomas.. Confirmed gains in chromosomes 5, 8,13,14,18 by enrichment analysis. Based on CNA and expression profiling we found G2 pathway, TNFR2, ATBRCA and other pathways enriched in stable vs unstable (3 or more aberrations) phenotypes. - Statistical multivariate analysis support the statistically significant relationship between genetic stability and survival of patients. SUBMITTED TO ONCOGENE. 15
16 Research lines. Role of DAX1 in Ewing s sarcoma. GE Whole genome arrays: GFP shrna EWS/FL1 shrna DAX shrna 16
17 Research Lines. Lung Adeocarcinoma Healthy/Tumoral/Peritumoral markers. Healthy distant tissue (H) 2 cm Healthy periphery tumour tissue (P) Tumour tissue (T) RNA isolation Analyzed tissues sscdna dscdna crna Bioinformatics analysis Affymetrix HG FocusArray crna fragments quality control 17
18 Research Lines. Lung Adeocarcinoma Healthy/Tumoral/Peritumoral markers. Functional analysis for differentially expressed genes in lung adenocarcinoma. 24 genes were found capable to discriminate among surgical classes (healthy, peritumoral and tumoral). 18
19 Research Lines. CpGs in EBV. 19
20 Research lines CARGO: Cancer And Related Genes On Line CARGO: a web portal to integrate customized biological information. Cases I, Pisano DG, Andres E, Carro A, Fernandez JM, Gomez-Lopez G, Rodriguez JM, Vera JF, Valencia A, Rojas AM. Nucleic Acids Res May
21 Research Lines CARGO: Cancer And Related Genes On Line 21
22 Industry Collaborations. Pharmamar. Effects of Yondelis treatment on sensitive and resistant cell lines. Functional analysis of microarrays points to effects on G2 pathway.. Experimental data support this analysis. 22
23 Academic Activities. -1 st Course on Functional Analysis (CNIO). -Summer School in Bioinformatics (UCM). -PhD Course in Bioinformatics (UAM). 23
24 Outline 24
25 Software tools 25
26 Outline 26
27 Target journals & conferences B-Cell Lymphomas transcriptome: Transcriptome classification of B-cell non-hodgkins lymphoma Mohit Aggarwal, Miguel A. Piris, Raquel Villuendas, Abel Sánchez-Aguilera, Nerea Martínez, Alberto Pérez, Paloma de la Cueva, María Jesús Artiga, Fatima Al-Sharour, Joaquín Dopazo, Gonzalo Gomez, Elena Ruiz-Ballesteros, Francisca I.Camacho, José A.García-Marco CNIO Cancer Conferences Molecular Mechanisms in Lymphoid Neoplasm Madrid, February Poster. Pending to be submitted to Nature Genetics. Genetic Instability in Ewing Sarcomas: Ewing s sarcomas integrated expression and arraycgh profiling reveals distinct genomic instability patterns associated with DNA repair and cell cycle checkpoint pathways Bibiana I. Ferreira (1), Javier Alonso (2) (*), Jaime Carrillo (2), Francesco Acquadro (1), Cristina Largo (1), Javier Suela (1), Manuel R. Teixeira (3); Nuno Ceveira (3), Alberto Molares (4), Gonzalo Goméz-López (4) (5), Ángel Pestaña (2), Ana Sastre (6), Purificacion Garcia-Miguel (6), and Juan C. Cigudosa (1) (*). Oncogene. On revision. Lung Adenocarcinomas Healthy/Tumoral/Peritumoral markers: crna Microarrays and Bioinformatics application in lung carcinoma samples. A.Molares, E.Carrillo, G.Gómez, G. Muñoz Molina, I. Muguruza, I.Sanchez, R.Moreno, V.Leiro, F.Carrillo, E.Caso. 5 th European Conference on Computational Biology, Eliat, Israel , Enero Poster. 27
28 Outline 28
29 Main Interests 29
30 Outline 30
31 Collaboration offered 31
32 Acknowledgements. UBio staff & PDG group Lymphoma s group Miguel Angel Piris Raquel Villuendas Mohit Aggarwal Cytogenetics group Juan C. Cigudosa Bibiana Ferreira. Childhood tumors group Javier Alonso CHUVI Bioinformatics group Enrique Caso Carmen M. Redondo Alberto Molares F. Fdez-Riverola Epigenetics group. Agustín Fernández. 32
Course on Functional Analysis. ::: Gene Set Enrichment Analysis - GSEA -
Course on Functional Analysis ::: Madrid, June 31st, 2007. Gonzalo Gómez, PhD. ggomez@cnio.es Bioinformatics Unit CNIO ::: Contents. 1. Introduction. 2. GSEA Software 3. Data Formats 4. Using GSEA 5. GSEA
What is Cancer? Cancer is a genetic disease: Cancer typically involves a change in gene expression/function:
Cancer is a genetic disease: Inherited cancer Sporadic cancer What is Cancer? Cancer typically involves a change in gene expression/function: Qualitative change Quantitative change Any cancer causing genetic
Course on Biobanks for research samples (2 nd 4 th October)
The Association of Biotechnology of organizes three different courses, in order to increase students knowledge in some topics related to Biotechnology, which are not usually included in Universities syllabi.
13 May 14 May. SESSION 2.- Advances in hearing loss research II Chair: Andrew Forge
13 May 14 May 15:00-17:00 Registration 15:45-16:00 Welcome on behalf of the organizers José María Millán. Unit of Genetics La Fé Hospital. CIBERER. Valencia. Spain. 16:00-16:30 Francesc Palau. CIBERER
ALCHEMIST (Adjuvant Lung Cancer Enrichment Marker Identification and Sequencing Trials)
ALCHEMIST (Adjuvant Lung Cancer Enrichment Marker Identification and Sequencing Trials) 3 Integrated Trials Testing Targeted Therapy in Early Stage Lung Cancer Part of NCI s Precision Medicine Effort in
Sarcoma Research Group Group leader: Òscar Martínez Tirado
Sarcoma Research Group Group leader: Òscar Martínez Tirado IDIBELL since 2007 Miguel Servet program (Fondo de Investigaciones Sanitarias) 2009 Sarcoma Research Group (SGR682) Group leader: Òscar Martínez
A novel molecular mechanism involved in cancer development revealed by targeting MafB to hematopoietic progenitors
A novel molecular mechanism involved in cancer development revealed by targeting MafB to hematopoietic progenitors Carolina Vicente Dueñas Instituto de Biología Molecular y Celular del Cáncer (IBMCC) (CSIC-Universidad
The EU s Seventh Framework Programme for R&D: Making the most of the 2013 Calls
The EU s Seventh Framework Programme for R&D: Making the most of the 2013 Calls DATE: 12 September 2012 TIMETABLE: From 9h30 to 17h15 VENUE: Headquarters of the Spanish National Research Council (CSIC)
The RNA strategy. RNA as a tool and target in human disease diagnosis and therapy.
The RNA strategy RNA as a tool and target in human disease diagnosis and therapy. The Laboratory of RNA Biology and Biotechnology at the Centre for Integrative Biology (CIBIO) of the University of Trento,
Diagnostic and Therapeutic Colonoscopy for Colorectal Neoplasia in the 21st Century: Focus on IBD
Marbella (Spain), January 29th & 30th, 2015 Diagnostic and Therapeutic Colonoscopy for Colorectal Neoplasia in the 21st Century: Preliminary Program Thursday, January 29th 2015 15:45-16:00 Welcome to the
ORGANIZERS Fundación para la Investigación Médica Aplicada FIMA Clínica Universidad de Navarra CUN
D International Symposium: Immunostimulatory monoclonal antibodies and immunomodulation: harvesting the crop Fundación Ramón Areces GENERAL INFORMATION DATES OCTOBER 18th 20th VENUE University of Navarra.
LYMPHOMA. BACHIR ALOBEID, M.D. HEMATOPATHOLOGY DIVISION PATHOLOGY DEPARTMENT Columbia University/ College of Physicians & Surgeons
LYMPHOMA BACHIR ALOBEID, M.D. HEMATOPATHOLOGY DIVISION PATHOLOGY DEPARTMENT Columbia University/ College of Physicians & Surgeons Normal development of lymphocytes Lymphocyte proliferation and differentiation:
TIGRE5-CM - Presentation
TIGRE5-CM - Presentation The aim of TIGRE5-CM project is to design an architecture for future generation mobile networks, based on the SDN (Software Defined Networking) paradigm, which eases the deployment,
Future Directions in Cancer Research What does is mean for medical physicists and AAPM?
Future Directions in Cancer Research What does is mean for medical physicists and AAPM? John D. Hazle, Ph.D., FAAPM, FACR President-elect American Association of Physicists in Medicine Professor and Chairman
The following information is only meant for people who have been diagnosed with advanced non-small cell
Important information for people with advanced non-small cell lung cancer The following information is only meant for people who have been diagnosed with advanced non-small cell lung cancer (NSCLC). NSCLC
Education Session 1. Education Session 2. Inaugural Session
WEDNESDAY 4 NOVEMBER 2015 Education Session 1 09:30-10:30 S1a: Cell and viral vector manufacturing and distribution under GMP Chair: Ana Sanchez S1b: Systems biology: computational methods applied to advanced
15 th ASEICA INTERNATIONAL CONGRESS
Sevilla 21-23 october 2015 15 th ASEICA Spanish Society for Cancer Research Hotel NH Collection Sevilla. Avda Diego Martinez Barrio, 8, 41013 Sevilla Organizing Committee President Dr. Pedro Lazo-Zbikowski
PREDA S4-classes. Francesco Ferrari October 13, 2015
PREDA S4-classes Francesco Ferrari October 13, 2015 Abstract This document provides a description of custom S4 classes used to manage data structures for PREDA: an R package for Position RElated Data Analysis.
Targeted Therapy What the Surgeon Needs to Know
Targeted Therapy What the Surgeon Needs to Know AATS Focus in Thoracic Surgery 2014 David R. Jones, M.D. Professor & Chief, Thoracic Surgery Memorial Sloan Kettering Cancer Center I have no disclosures
mixomics: a software for researchers to analyse large data sets
mixomics: a software for researchers to analyse large data sets The University of Queensland Diamantina Institute Brisbane, Australia Systems biology Systems biology is the study of complex interactions
How To Contact Cotransa
COTRANSA - Key Contact Details Physical address: MADRID (HEAD OFFICE) Avda Central, Parcela 2.5, Naves 1 y 3. 28042 Centro de carga aerea Marid-Barajas Madrid (SPAIN) Tel: +34 917 46 06 80 Fax: +34 913
CancerStemCell Markers in Lung Cancers: Proofsof. Reservations. Lourdes Cortes-Dericks, PhD University of Hamburg Hamburg, Germany
CancerStemCell Markers in Lung Cancers: Proofsof ConceptsandSome Reservations Lourdes Cortes-Dericks, PhD University of Hamburg Hamburg, Germany Lung cancer: highest death rate and poorest patient survival
Outline. Predictive Assays in Radiation Therapy Immunotherapy in Cancer Treatment. Introduction. Current clinical practice
Predictive Assays in Radiation Therapy Immunotherapy in Cancer Treatment Radiation Biology Outline Introduction: Predictive assays in radiation therapy Examples for specific tumors Immunotherapy Summary
About B Cell Lymphomas Groupmeeting Klipp/Spang, December 09 2002 Dennis Kostka Max-Planck-Institute for Molecular Genetics Computational Molecular Biology Berlin 1 Overview Short History of Lymphoma Classification
Medical Informatics II
Medical Informatics II Zlatko Trajanoski Institute for Genomics and Bioinformatics Graz University of Technology http://genome.tugraz.at zlatko.trajanoski@tugraz.at Medical Informatics II Introduction
Just the Facts: A Basic Introduction to the Science Underlying NCBI Resources
1 of 8 11/7/2004 11:00 AM National Center for Biotechnology Information About NCBI NCBI at a Glance A Science Primer Human Genome Resources Model Organisms Guide Outreach and Education Databases and Tools
Local Courses s REPORT
Project cofinanced by European Regional Development Fund Project cofinancé par le Fonds européen de développement régional 1G-MED08-515 Sustainable Water Management through Common Responsibility enhancement
Analysis of gene expression data. Ulf Leser and Philippe Thomas
Analysis of gene expression data Ulf Leser and Philippe Thomas This Lecture Protein synthesis Microarray Idea Technologies Applications Problems Quality control Normalization Analysis next week! Ulf Leser:
PhD English Linguistics UCM Research groups
PhD English Linguistics UCM Research groups Research groups led by faculty members: GROUP I REFERENCE 930175 RESEARCH GROUP UCM: Functional linguistics (English-Spanish) and its applications Dr. Julia
Cancer SBL101. James Gomes School of Biological Sciences Indian Institute of Technology Delhi
Cancer SBL101 James Gomes School of Biological Sciences Indian Institute of Technology Delhi All Figures in this Lecture are taken from 1. Molecular biology of the cell / Bruce Alberts et al., 5th ed.
Nuevas tecnologías basadas en biomarcadores para oncología
Nuevas tecnologías basadas en biomarcadores para oncología Simposio ASEBIO 14 de marzo 2013, PCB Jose Jimeno, MD, PhD Co-Founder / Vice Chairman Pangaea Biotech SL Barcelona, Spain PANGAEA BIOTECH BUSINESS
Updated: 18/2/2015 PERSONAL PROFILE
Carlos J. Perez del Pulgar Escuela de Ingenierías C/Ortiz Ramos s/n 29071 Málaga (Spain) Landline: +34 951952324 Email: carlosperez@uma.es www.isa.uma.es/cperez Updated: 18/2/2015 PERSONAL PROFILE Since
Translocation Renal Cell Carcinomas: Molecular insights and Future Directions
Translocation Renal Cell Carcinomas: Molecular insights and Future Directions Gabriel G. Malouf, MD, PhD Assistant professor Department of medical oncology Pitié-Salpêtrière Hospital, Paris, France Background
CNIO Frontiers Meetings Molecular Cancer Therapeutics Madrid, March 8 10, 2010
CNIO Frontiers Meetings Molecular Cancer Therapeutics Madrid, March 8 10, 2010 Organisers S. Gail Eckhardt, University of Colorado Denver, Aurora, USA Roy S. Herbst, The University of Texas MD Anderson
AGILENT S BIOINFORMATICS ANALYSIS SOFTWARE
ACCELERATING PROGRESS IS IN OUR GENES AGILENT S BIOINFORMATICS ANALYSIS SOFTWARE GENESPRING GENE EXPRESSION (GX) MASS PROFILER PROFESSIONAL (MPP) PATHWAY ARCHITECT (PA) See Deeper. Reach Further. BIOINFORMATICS
New Hampshire Childhood Cancer
Introduction: New Hampshire Childhood Cancer New Hampshire, Childhood Cancer, January 2009 Issue Brief Cancer in children is relatively uncommon, impacting fewer than twenty two of every 100,000 children
Advanced School on Molecular and Cell Biology to Unravel the Physiology/Pathology of Diverse Biological Foreign Proffesors
Advanced School on Molecular and Cell Biology to Unravel the Physiology/Pathology of Diverse Biological Foreign Proffesors Names Address Scientific interest Dr. Ernesto Venetian "Calcium Signalling in
Comparative genomic hybridization Because arrays are more than just a tool for expression analysis
Microarray Data Analysis Workshop MedVetNet Workshop, DTU 2008 Comparative genomic hybridization Because arrays are more than just a tool for expression analysis Carsten Friis ( with several slides from
Diagnostic and Therapeutic Colonoscopy for Colorectal Neoplasia in the 21st Century: Expanding the Scope to IBD
Marbella (Spain), January 17th & 18th, 2013 Diagnostic and Therapeutic Colonoscopy for Colorectal Neoplasia in the 21st Century: Thursday, January 17th 2013 8:45-9:00 Welcome to the Hands-on Course Andres
Identification of rheumatoid arthritis and osteoarthritis patients by transcriptome-based rule set generation
Identification of rheumatoid arthritis and osterthritis patients by transcriptome-based rule set generation Bering Limited Report generated on September 19, 2014 Contents 1 Dataset summary 2 1.1 Project
Analysis of the colorectal tumor microenvironment using integrative bioinformatic tools
MLECNIK Bernhard & BINDEA Gabriela Analysis of the colorectal tumor microenvironment using integrative bioinformatic tools INSERM U872, Jérôme Galon Team15: Integrative Cancer Immunology Cordeliers Research
Electronic access to mouse tumor data: the Mouse Tumor Biology Database (MTB) project
1999 Oxford University Press Nucleic Acids Research, 1999, Vol. 27, No. 1 99 105 Electronic access to mouse tumor data: the Mouse Tumor Biology Database (MTB) project Carol J. Bult*, Debra M. Krupke and
R. Julian Preston NHEERL U.S. Environmental Protection Agency Research Triangle Park North Carolina. Ninth Beebe Symposium December 1, 2010
Low Dose Risk Estimation: The Changing Face of Radiation Risk Assessment? R. Julian Preston NHEERL U.S. Environmental Protection Agency Research Triangle Park North Carolina Ninth Beebe Symposium December
MASTER ON COMPUTATIONAL BIOTECHNOLOGY
MASTER ON COMPUTATIONAL BIOTECHNOLOGY 1.- GENERAL FEATURES OF THE POSTGRADUATE PROGRAM 1.1.- Program name Communication and Information Technologies 1.2.- Coordinator of the program Mariano Fernández López
From Immunotherapy of Cancer to the Discovery of Kidney Cancer Genes
ISSN 2154-4006 The Genetic Basis of Human Disease zbar Colloquium series on Series Editor: Michael Dean, Ph.D., Head, Human Genetics Section, Senior Investigator, Laboratory of Experimental Immunology
microrna Signatures in Cancer E. ROBERT WASSMAN, MD, FAAP, FACMG CHIEF MEDICAL OFFICER, ROSETTA GENOMICS
microrna Signatures in Cancer E. ROBERT WASSMAN, MD, FAAP, FACMG CHIEF MEDICAL OFFICER, ROSETTA GENOMICS 1st International Congress on Controversies in Personalized Oncology (CONPO) BARCELONA, SPAIN MARCH
Analysing functional genomics data using novel ensemble, consensus and data fusion techniques
Analysing functional genomics data using novel ensemble, consensus and data fusion techniques by Enrico Glaab Thesis submitted to The University of Nottingham for the Degree of Doctor of Philosophy School
A powerful model of endometrial carcinogenesis! molecular analysis and rational design of immunological intervention approaches
A powerful model of endometrial carcinogenesis! molecular analysis and rational design of immunological intervention approaches Afrouz Behboudi PhD, Associate Prof. School of Life Sciences, University
Sommaire projets sélectionnés mesure 29: Soutien à la recherche translationnelle
Sommaire projets sélectionnés mesure 29: Soutien à la recherche translationnelle TITLE PROJET NOM HOPITAL Assessment of tumor angiogenesis using PET/CT with 18 F-Galacto- RGD. (PNC_29_001) Division of
The Isabel Application
The Isabel Application Prof. Juan Quemada Dept. of Telematic Engineering Universidad Politécnica de Madrid ISABEL Advanced multiconferencing system 4Developed at UPM since 1993 (RACE/ACTS/IST) http://isabel.dit.upm.es
FlipFlop: Fast Lasso-based Isoform Prediction as a Flow Problem
FlipFlop: Fast Lasso-based Isoform Prediction as a Flow Problem Elsa Bernard Laurent Jacob Julien Mairal Jean-Philippe Vert September 24, 2013 Abstract FlipFlop implements a fast method for de novo transcript
CCR Biology - Chapter 9 Practice Test - Summer 2012
Name: Class: Date: CCR Biology - Chapter 9 Practice Test - Summer 2012 Multiple Choice Identify the choice that best completes the statement or answers the question. 1. Genetic engineering is possible
Pathology of lung cancer
Pathology of lung cancer EASO COURSE ON LUNG CANCER AND MESOTHELIOMA DAMASCUS (SYRIA), MAY 3-4, 2007 Gérard ABADJIAN MD Pathologist Associate Professor, Saint Joseph University Pathology Dept. Hôtel-Dieu
Malignant Lymphomas and Plasma Cell Myeloma
Malignant Lymphomas and Plasma Cell Myeloma Dr. Bruce F. Burns Dept. of Pathology and Lab Medicine Overview definitions - lymphoma lymphoproliferative disorder plasma cell myeloma pathogenesis - translocations
Rilevanza dell innovazione tecnologica per la
Rilevanza dell innovazione tecnologica per la ricerca traslazionale e la terapia in oncologia Ruggero De Maria Dipartimento di Ematologia Oncologia e Medicina Molecolare, Istituto Superiore di Sanità Translational
ADMINISTRATION BOARD OF TRUSTEES. Appointed Members. Honorary President. Elected Members. Secretary
ADMINISTRATION BOARD OF TRUSTEES Honorary President Appointed Members Elected Members Secretary Luis de Guindos Jurado Minister of Economy and Competitiveness Ministro de Economía y Competitividad President
PRINIPLES OF RADIATION THERAPY Adarsh Kumar. The basis of radiation therapy revolve around the principle that ionizing radiations kill cells
PRINIPLES OF RADIATION THERAPY Adarsh Kumar The basis of radiation therapy revolve around the principle that ionizing radiations kill cells Radiotherapy terminology: a. Radiosensitivity: refers to susceptibility
A 32 year old woman comes to your clinic with neck masses for the last several weeks. Masses are discrete, non matted, firm and rubbery on
A 32 year old woman comes to your clinic with neck masses for the last several weeks. Masses are discrete, non matted, firm and rubbery on examination. She also has fever, weight loss, and sweats. What
LEUKEMIA LYMPHOMA MYELOMA Advances in Clinical Trials
LEUKEMIA LYMPHOMA MYELOMA Advances in Clinical Trials OUR FOCUS ABOUT emerging treatments Presentation for: Judith E. Karp, MD Advancements for Acute Myelogenous Leukemia Supported by an unrestricted educational
http://www.springer.com/3-540-22006-2
http://www.springer.com/3-540-22006-2 1 Molecular Pathology Laboratory of the Future Christopher A. Moskaluk 1.1 The Past The integration of laboratory analysis with human medicine has traditionally been
Organization and analysis of NGS variations. Alireza Hadj Khodabakhshi Research Investigator
Organization and analysis of NGS variations. Alireza Hadj Khodabakhshi Research Investigator Why is the NGS data processing a big challenge? Computation cannot keep up with the Biology. Source: illumina
The Role of Genetic Testing in the Evaluation of Thyroid Nodules. Thyroid Cancer and FNA. Thyroid Cancer. Pure Follicular Cancers.
Where does Molecular Analysis of FNA Specimens fit into the evaluation of thyroid nodules? The Role of Genetic Testing in the Evaluation of Thyroid Nodules Ultrasound TSH Risk factors Jill E. Langer, MD
BRAF in the diagnostic evaluation of thyroid nodules
Symposium 13 Molecular markers in thyroid cancer: current role in clinical practice BRAF in the diagnostic evaluation of thyroid nodules Laura Fugazzola University of Milan, Italy Papillary carcinoma BRAF
FELLOWSHIPS IN THE STUDENT PARTNERSHIP PROGRAM
FELLOWSHIPS IN THE STUDENT PARTNERSHIP PROGRAM Date of decision: Wednesday, November 27, 2013 NORMALUX POSTER: EasyChair 28: Home charge system for EVs with peak power smoothing based on renewable energy.
- Slide Seminar - Endocrine pathology in non-endocrine organs. Case 11. Stefano La Rosa, Gioacchino D Ambrosio, Fausto Sessa
- Slide Seminar - Endocrine pathology in non-endocrine organs Case 11 Stefano La Rosa, Gioacchino D Ambrosio, Fausto Sessa Dept. of Pathology, Multimedica, Milan, Italy Dept. of Surgical and Morphological
Dal germinale al somatico nella identificazione di tumori ereditari
Modena 18-19 novembre 2010 Dal germinale al somatico nella identificazione di tumori ereditari Laura Ottini Tendencies to develop cancer can be inherited Fletcher & Houlston, 2010 Cancer is a genetic disease
Looking at the Future of Industrial Engineering in Europe... 3 Giovanni Mummolo
Contents Part I Management Looking at the Future of Industrial Engineering in Europe... 3 Giovanni Mummolo A Collaborative Me Crossroad: Individual Beliefs and the Adoption of Corporate Blogs... 19 Pedro
An unsupervised fuzzy ensemble algorithmic scheme for gene expression data analysis
An unsupervised fuzzy ensemble algorithmic scheme for gene expression data analysis Roberto Avogadri 1, Giorgio Valentini 1 1 DSI, Dipartimento di Scienze dell Informazione, Università degli Studi di Milano,Via
Towards the utilization of cannabinoids as anti-cancer
Towards the utilization of cannabinoids as anti-cancer agents Guillermo Velasco Sestri Levante September 2015 Anti-cancer activity of cannabinoids Munson et al. (1975) Antineoplastic activity of cannabinoids
Molecular Diagnostics in Thyroid Cancer
Disclosure Nothing to disclose Jonathan George, MD, MPH Assistant Professor Head and Neck Oncologic & Endocrine Surgery Molecular Diagnostics in Thyroid Cancer Current Practices & Future Trends UCSF Medical
Technology funding opportunities at the National Cancer Institute
Technology funding opportunities at the National Cancer Institute Through the Cancer Diagnosis Program http://cancerdiagnosis.nci.nih.gov/index.html Avraham Rasooly Ph.D. National Cancer Institute, Cancer
INDUSTRY-ACADEMIC-CLINICAL FORUM
INDUSTRY-ACADEMIC-CLINICAL FORUM FUTURE TRENDS IN NANOMEDICINE FOR DIAGNOSTICS AND THERAPY IN ONCOLOGY Parc Científic de Barcelona / Barcelona Science Park 25 th of October of 2012 TABLE OF CONTENTS Agenda
Row Quantile Normalisation of Microarrays
Row Quantile Normalisation of Microarrays W. B. Langdon Departments of Mathematical Sciences and Biological Sciences University of Essex, CO4 3SQ Technical Report CES-484 ISSN: 1744-8050 23 June 2008 Abstract
American Cancer Society Extramural Grants
Page: 1 Graduate Scholarships in Cancer Nursing Practice (GSCNP) GSCNP-14-118-01 Abbott, Linda, MSN MENTOR: Hooke, Mary C., PhD, RN School of Nursing Graduate Scholarship in Cancer Nursing Practice 07/01/2014
Developments in Biomarker Identification and Validation for Lung Cancer
Developments in Biomarker Identification and Validation for Lung Cancer Alexandre Passioukov, MD, PhD Alexandre.Passioukov@eortc.be Contents Introduction Lung cancer pathogenesis NSCLC treatment options
Course Curriculum for Master Degree in Medical Laboratory Sciences/Clinical Biochemistry
Course Curriculum for Master Degree in Medical Laboratory Sciences/Clinical Biochemistry The Master Degree in Medical Laboratory Sciences /Clinical Biochemistry, is awarded by the Faculty of Graduate Studies
The Human Genome Project. From genome to health From human genome to other genomes and to gene function Structural Genomics initiative
The Human Genome Project From genome to health From human genome to other genomes and to gene function Structural Genomics initiative June 2000 What is the Human Genome Project? U.S. govt. project coordinated
CHAPTER 2: UNDERSTANDING CANCER
CHAPTER 2: UNDERSTANDING CANCER INTRODUCTION We are witnessing an era of great discovery in the field of cancer research. New insights into the causes and development of cancer are emerging. These discoveries
Lymphoma Diagnosis and Classification
Lymphoma Diagnosis and Classification By Atef Shrit, MD, Pathology B- and T/NK-cell lymphomas are clonal neoplasms of immature and mature B-lymphocytes, T-lymphocytes or natural killer cells at various
FACULTY OF ALLIED HEALTH SCIENCES
FACULTY OF ALLIED HEALTH SCIENCES 102 Naresuan University FACULTY OF ALLIED HEALTH SCIENCES has focused on providing strong professional programs, including Medical established as one of the leading institutes
Cystic Fibrosis Webquest Sarah Follenweider, The English High School 2009 Summer Research Internship Program
Cystic Fibrosis Webquest Sarah Follenweider, The English High School 2009 Summer Research Internship Program Introduction: Cystic fibrosis (CF) is an inherited chronic disease that affects the lungs and
Molekylært målrettet medicinsk kræftbehandling for klinikere principper og metoder
Molekylært målrettet medicinsk kræftbehandling for klinikere principper og metoder Professor Claus Lindbjerg Andersen Department of Molecular Medicine (MOMA) Aarhus University hospital Outline The central
Regulation of telomeres by mirnas in human cancer
Regulation of telomeres by mirnas in human cancer Stefan Schoeftner, PhD LNCIB, Trieste stefan.schoeftner@lncib.it SIES Discutiamo Insieme Florence, 2.11.214 Shelterin components and telomerase are key
What is Cancer? Section 2 - What Is Cancer? - 1 -
What is Cancer? Normal Growth The human body is made up of many millions of tiny building blocks called cells. Each organ of the body (eg. brain, liver, muscle) contains its own special types of cells,
Interesting Case Review. Renuka Agrawal, MD Dept. of Pathology City of Hope National Medical Center Duarte, CA
Interesting Case Review Renuka Agrawal, MD Dept. of Pathology City of Hope National Medical Center Duarte, CA History 63 y/o male with h/o CLL for 10 years Presents with worsening renal function and hypercalcemia
Dr Alexander Henzing
Horizon 2020 Health, Demographic Change & Wellbeing EU funding, research and collaboration opportunities for 2016/17 Innovate UK funding opportunities in omics, bridging health and life sciences Dr Alexander
SUMMARY. Randolph Fillmore, Florida Science Communications
SUMMARY Randolph Fillmore, Florida Science Communications The H. Lee Moffitt Cancer Center held its first Advanced Prostate Cancer Collaboration roundtable discussion November 24, 2008. The roundtable
Cancer. 9p21.3 deletion. t(12;21) t(15;17)
CANCER FISH PROBES INDIVIDUAL AND PANEL S Acute Lymphoblastic Leukemia (ALL) ALL FISH Panel (includes all probes below) 8010 LSI MYB/CEP6 LSI p16 (CDKN2A) LSI BCR/ABL with ASS LSI ETV6 (TEL)/AML1 (RUNX1)
Escola Universitaria de Turismo - Mobilidade Internacional Erasmus (estudios) 2015-2016 Listaxe definitivo
Escola Universitaria de - Mobilidade Internacional Erasmus (estudios) 2015-2016 Listaxe definitivo 2015-2016 Paloma Acuña Garrido 48111969V Rumania 1 10 1S2015/16 Paloma Acuña Garrido 48111969V 2 10 1S2015/16
Human Genetics: Online Resources
Human Genetics: Online Resources David A Adler, ZymoGenetics, Seattle, Washington, USA There is a large source of information concerning human genetics available on a variety of different Internet sites,
Pharmacogenomic Approaches. Luis Paz-Ares Hospital Universitario Virgen del Rocio Seville, Spain
Pharmacogenomic Approaches Luis Paz-Ares Hospital Universitario Virgen del Rocio Seville, Spain Pharmacogenetics & Pharmacogenomics Medicine tailored to the individual Genetic information, including the
PRACTICAL APPROACH TO ECOTOXICOGENOMICS
ANNOUNCEMENT PRACTICAL APPROACH TO ECOTOXICOGENOMICS Advanced Workshop Studies in Biology and Applied Biosciences Department of Biology University of Aveiro, 30 April- 4 May 2007 This one-week post-graduate
Analysis of Illumina Gene Expression Microarray Data
Analysis of Illumina Gene Expression Microarray Data Asta Laiho, Msc. Tech. Bioinformatics research engineer The Finnish DNA Microarray Centre Turku Centre for Biotechnology, Finland The Finnish DNA Microarray
Lung Carcinomas New 2015 WHO Classification. Spasenija Savic Pathology
Lung Carcinomas New 2015 WHO Classification Spasenija Savic Pathology ***EXPECTED SPRING 2015*** This authoritative, concise reference book provides an international standard for oncologists and pathologists
Master in Finance & Banking Edition 2015 / 2016. Faculty
Master in Finance & Banking Edition 2015 / 2016 Faculty Eliseo Navarro Arribas (Direction) FACULTY PhD in Applied Economics and Finance from the Universidad de Valencia. Postgraduate Diploma in Actuarial
Lesson 3 Reading Material: Oncogenes and Tumor Suppressor Genes
Lesson 3 Reading Material: Oncogenes and Tumor Suppressor Genes Becoming a cancer cell isn t easy One of the fundamental molecular characteristics of cancer is that it does not develop all at once, but
Intelligent Data Analysis
Intelligent Data Analysis for Real-Life Applications: Theory and Practice Rafael Magdalena-Benedito Marcelino Martinez-Sober Jose Maria Martinez-Martinez Pablo Escandell-Montero Joan Vila-Frances Information
Cancer Genomics: What Does It Mean for You?
Cancer Genomics: What Does It Mean for You? The Connection Between Cancer and DNA One person dies from cancer each minute in the United States. That s 1,500 deaths each day. As the population ages, this
Data Integration. Lectures 16 & 17. ECS289A, WQ03, Filkov
Data Integration Lectures 16 & 17 Lectures Outline Goals for Data Integration Homogeneous data integration time series data (Filkov et al. 2002) Heterogeneous data integration microarray + sequence microarray
Molecular markers and clinical trial design parallels between oncology and rare diseases?
Molecular markers and clinical trial design parallels between oncology and rare diseases?, Harriet Sommer Institute for Medical Biometry and Statistics, University of Freiburg Medical Center 6. Forum Patientennahe