15 th ASEICA INTERNATIONAL CONGRESS

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1 Sevilla october th ASEICA Spanish Society for Cancer Research Hotel NH Collection Sevilla. Avda Diego Martinez Barrio, 8, Sevilla

2 Organizing Committee President Dr. Pedro Lazo-Zbikowski Dr. Carlos Camps Dr. Noemí Reguart Dr. Gabriel Capellá Dr. Montserrat Sánchez Cespedes Dr. Luis Paz-Ares Dr. Ana Osorio Dr. Arkaitz Carracedo Dr. Jesús Paramio Dr. José Palacios Scientific Committee Dr. Pedro Lazo-Zbikowski Dr. Carlos Camps Dr. Gabriel Capellà Dr. Arkaitz Carracedo Dr. Leonor David Dr. Antonio García de Herreros Dr. Alberto Muñoz Dr. Ana Osorio Dr. José Palacios Dr. Jesús Paramio Dr. Luis Paz-Ares Dr. Héctor Peinado Dr. Noemí Reguart Dr. Montse Sánchez-Céspedes Dr. Joan Seoane Dr. Violeta Serra Dr. George Thomas Dr. Guillermo Velasco Meeting opening Opening conference. ASEICA Lecture Targetting telomeres in cancer Dr. María A. Blasco, Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid Sustaining proliferative signaling & evading growth suppressors Chairpersons Dr. Jesús Paramio and Dr. Violeta Serra Linking senescence and inflammation: the senescence-associated secretory phenotype (SASP) Dr. Jesús Gil, MRC Clinical Science Center, Kings College, London, UK Targeting PI3K in breast cancer Dr. Violeta Serra, Hospital Universitari Vall d Hebrón (VHIO), Barcelona Tyrosine kinase inhibitors: from Lazarians responses to the emergence of resistance. A focus in lung cancer Dr. Luis Paz-Ares, Hospital Universitario 12 de Octubre, Madrid

3 Cancer genomics and tumor heterogeneity Chairpersons Dr. Montse Sánchez-Céspedes and Dr. José Palacios Novel gene alterations and biological networks in lung cancer development Dr. Montse Sánchez-Céspedes, Instituto de Investigación Biomédica de Bellvitge (IDIBELL), Barcelona Genomic characterization of the role of intratumor heterogeneity in cancer progression and metastasis Dr. Ignacio Varela, Instituto de Biomedicina y Biotecnología de Cantabria (IBBTEC - UC - CSIC - SODERCAN), Santander Clinical implications of intrinsic breast cancer subtypes Dr. Aleix Prat, Hospital Universitari Clínic, Barcelona Round table: clinical applications of genomics Chairperson Dr. Luis Paz-Ares Clonal evolution and drug resistance: from cancer avatars to liquid biopsies Dr. Alberto Bardelli, University of Torino, Italy Discussants: Dr. Alberto Bardelli, University of Torino, Italy Dr. Joan Albanell, Hospital del Mar-Parc de Salut Mar, Barcelona Dr. Alfonso Berrocal, Hospital General Universitario, Valencia Metabolism. Deregulating cellular energetics Chairpersons Dr. George Thomas and Dr. Arkaitz Carracedo Ribosome biogenesis mediates a novel intrinsic p53 checkpoint in cancer progression Dr. George Thomas, Instituto de Investigación Biomédica de Bellvitge (IDIBELL), Barcelona mtor in intestinal cancer and metabolism Dr. Nabil Djouder, Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid Metabolic alterations as biomarkers of efficacy in anticancer therapies targeting the PI3K/AKT/mTOR pathway Dr. Jordi Rodón, Hospital Universitari Vall d Hebrón (VHIO), Barcelona Metabolic reprogramming as an escape mechanism against treatment with multi-tyrosine kinase inhibitors Dr. Miguel Quintela, Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid

4 Resisting cell death Chairpersons Dr. Guillermo Velasco and Dr. Gabriel Capellà Signaling mechanisms involved in the regulation of autophagy-mediated cancer cell death Dr. Guillermo Velasco, Universidad Complutense de Madrid, Instituto de Investigaciones Santarias San Carlos, Madrid The two faces of mesenchymal stem cells in myeloid neoplasias Dr. Simón Méndez-Ferrer, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid Cell death induced by inhibition of glucose metabolism Dr. Cristina Muñoz-Pinedo, Instituto de Investigación Biomédica de Bellvitge (IDIBELL), Barcelona Activating invasion & metastasis Chairpersons Dr. Antonio García de Herreros and Dr. Noemí Reguart Snail1, epithelial to mesenchymal transition and fibroblast activation Dr. Antonio García de Herreros, Universidad Pompeu Fabra (UPF), Barcelona Microenviromental regulation of disseminated tumour cells dormancy Dr. Paloma Bragado, Institut d Investigacions Biomèdiques Agustí Pi i Sunyer (IDIBAPS), Barcelona Signalling networks in inflammation and cancer Dr. Erwin Wagner, Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid SATELLITE SYMPOSIUM Lunch Poster session with presenters (odd numbers from to 15.00h, even numbers from to 16.00h)

5 Tumor niche and microenvironment Chairpersons Dr. Héctor Peinado and Dr. Joan Seoane Defining the role of tumor secreted exosomes during premetastatic niche formation Dr. Héctor Peinado, Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid Nuevos sensores de microambiente como genes supresores Dr. Amancio Carnero, Campus Hospital Universitario Virgen del Rocío (IBIS), Sevilla The TGF-beta pathway as a therapeutic target against cancer Dr. Joan Seoane, Hospital Universitari Vall d Hebrón (VHIO), Barcelona ASPIC Lecture Chairperson Dra. Leonor David The biology and functional contribution of exosomes in cancer progression and metastasis Dr. Sonia Melo, MD Anderson Cancer Center, USA and IPATIMUB-Univ. of Porto, Portugal SATELLITE SYMPOSIUM Nuclear receptors, transcription and cancer Chairpersons Dr. Alberto Muñoz and Dr. Ana Osorio Targeting nuclear receptors: why we need new combinatorial therapies for breast cancer Dr. María del Mar Vivanco, CIC biogune, Vizcaya Role of the transcriptional repressor HDAC7 in leukemia and lymphoma Dr. Maribel Parra, Instituto de Investigación Biomédica de Bellvitge (IDIBELL), Barcelona Vitamin D, VDR and colon cancer Dr. Alberto Muñoz, Instituto de Investigaciones Biomédicas, CSIC-UAM, Madrid

6 Closing session Chairpersons Dr. Pedro A. Lazo and Dr. Carlos Camps Awards ASEICA AND EACR prizes to best communications 1 st ASEICA Young Investigator Award 1 st ASEICA Cancer Research Award Closing lectures Connecting intestinal stem cells to colorectal cancer Dr. Eduard Batlle, Institut de Recerca Biomèdica (IRB), Barcelona 15 th ASEICA Spanish Society for Cancer Research EACR Lecture Targeting K-Ras signaling in cancer Dr. Mariano Barbacid, Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid ASEICA general assembly

7 Organized by With the special support of Technical Secretariat TACTICS MD París 162, Pral 1, Barcelona - T

15 th ASEICA INTERNATIONAL CONGRESS

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