Name of Subsidiary U.S. Subsidiaries: Advanced Sterilization Products Services Inc. Advanced Technologies and Regenerative Medicine, LLC

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1 Subsidiaries Johnson & Johnson, a corporation, had the domestic and international subsidiaries shown below as of December 30, Certain U.S. subsidiaries and international subsidiaries are not named because they were not significant in the aggregate. Johnson & Johnson has no parent. Source: Johnson & Johnson 2008 Form 10-K Name of Subsidiary U.S. Subsidiaries: Advanced Sterilization Products Services Inc. Advanced Technologies and Regenerative Medicine, LLC ALZA Corporation ALZA Development Corporation ALZA Land Management, Inc. Animas Corporation Biosense Webster, Inc. Centocor Biologics, LLC Centocor, Inc. Centocor Ortho Biotech Services LLC Centocor Research & Development, Inc. Closure Medical Corporation CNA Development LLC Codman & Shurtleff, Inc. Conor Medsystems, LLC Cordis Corporation Cordis Development Corporation Cordis International Corporation Cordis LLC Cordis Neurovascular, Inc. Crescendo Pharmaceuticals Corporation DePuy, Inc. DePuy Mitek, Inc. DePuy Orthopaedics, Inc. DePuy Products, Inc. DePuy Spine, Inc. California California Massachusetts Indiana Indiana Ohio 1

2 DePuy Spine Sales Limited Partnership Diabetes Diagnostics, Inc. Ethicon Endo-Surgery, Inc. Ethicon Endo-Surgery, LLC Ethicon Endo-Surgery Services, L.P. Ethicon, Inc. Ethicon LLC Global Biologics Supply Chain, LLC GUH Corporation GynoPharma Inc. Hand Innovations LLC HealthMedia, Inc. Innovational Holdings, LLC ISO Holding Corp. J&J Holdings (Nevada), Inc. Janssen Ortho LLC JJHC, LLC JNJ International Investment LLC Johnson & Johnson Baby Products, Inc. Johnson & Johnson Consumer Companies, Inc. Johnson & Johnson Development Corporation Johnson & Johnson Finance Corporation Johnson & Johnson Health Care Systems Inc. Johnson & Johnson International Johnson & Johnson Japan Inc. Johnson & Johnson Merck Consumer Pharmaceuticals Co. Johnson & Johnson (Middle East) Inc. Johnson & Johnson Pharmaceutical Research & Development, L.L.C. Johnson & Johnson Pharmaceutical Services, LLC Johnson & Johnson Professional Co. (P.R.) Inc. Johnson & Johnson Sales and Logistics Company, LLC Johnson & Johnson Services, Inc. Johnson & Johnson Urban Renewal Associates Johnson & Johnson Vision Care, Inc. Massachusetts Ohio Texas Michigan Nevada 2

3 Joint Medical Products Corporation LGE Performance Systems, Inc. LifeScan, Inc. LifeScan LLC LifeScan Products, LLC LuMend, Inc. McNeil Consumer Healthcare Latin America LLC McNeil Healthcare LLC McNeil LA LLC McNeil Nutritionals, LLC McNEIL-PPC, Inc. Middlesex Assurance Company Limited Neutrogena Corporation Nitinol Development Corporation Noramco, Inc. OMJ Pharmaceuticals, Inc. Omrix Biopharmaceuticals, Inc. OraPharma, Inc. Ortho Biologics LLC Ortho Biotech Holding Corp. Ortho Biotech Inc. Ortho Biotech Products, L.P. Ortho-Clinical Diagnostics, Inc. Ortho-McNeil Finance Co. Ortho-McNeil-Janssen Pharmaceuticals, Inc. Patriot Pharmaceuticals, LLC Rutan Realty LLC Scios Inc. SurgRx, Inc. TERAMed Corporation Therapeutic Discovery Corporation The Tylenol Company TransForm Pharmaceuticals, Inc. Veridex, LLC California Vermont California Georgia New York 3

4 International Subsidiaries: Alza Limited Amic AB Apsis S.A.S. Beijing Dabao Cosmetics Co., Ltd. Biosense Webster (Israel) Ltd. Carlo Erba OTC S.r.l. Centocor Biologics () Centocor B.V. Cilag Advanced Technologies GmbH Cilag AG Cilag de, S. de R.L. de C.V. Cilag GmbH International Cilag Holding AG Cilag Pharmaceuticals GmbH Codman Sarl ColBar LifeScience Ltd. Cordis Cashel Cordis de, S.A. de C.V. Cordis Europa N.V. Cordis Medizinische Apparate GmbH Cordis S.A.S. DePuy Ace Sarl DePuy International Limited DePuy International (Holdings) Limited DePuy () DePuy Mitek Sarl DePuy Orthopadie GmbH DePuy Spine Sarl DePuy UK Holdings Limited EES Holdings de, S. de R. L. de C. V. EES, S.A. de C.V. Ethicon Israel Israel 4

5 Ethicon Sarl Ethicon SAS Ethicon Women s Health & Urology Sarl Ethnor Del Istmo S.A. Ethnor Farmaceutica, S.A. FMS Future Medical System SA GMED Health Care Limited Group Vendôme SAS High Wycombe Property Management Limited Janssen-Cilag AB Janssen-Cilag A/S Janssen-Cilag AG Janssen-Cilag B.V. Janssen-Cilag Farmaceutica, Lda. Janssen-Cilag Farmaceutica Ltda. Janssen-Cilag GmbH Janssen-Cilag Ltd. Janssen-Cilag Limited Janssen-Cilag NV Janssen-Cilag OY Janssen-Cilag Pharmaceutical S.A.C.I. Janssen-Cilag Pharma GmbH Janssen-Cilag Polska, Sp. z o.o. Janssen-Cilag Pty. Ltd. Janssen-Cilag, S.A. Janssen-Cilag, S.A. de C.V. Janssen-Cilag S.A.S. Janssen-Cilag S.p.A. Janssen Korea Ltd. Janssen-Ortho Inc. Janssen Pharmaceutica NV Janssen Pharmaceutica (Pty) Limited Janssen Pharmaceutical K.K. Panama Venezuela Denmark Portugal Brazil Thailand Finland Greece Austria Poland Spain Korea Canada South Africa Japan 5

6 Janssen Pharmaceutical J.C. General Services CVBA J-C Healthcare Ltd. JHC Nederland B.V. Johnson & Johnson AB Johnson & Johnson AG Johnson & Johnson () Investment Co., Ltd. Johnson & Johnson () Ltd. Johnson & Johnson Consumer SAS Johnson & Johnson Consumer Healthcare S.r.l. Johnson & Johnson Consumer (Hong Kong) Limited Johnson & Johnson Consumer Services EAME Ltd. Johnson & Johnson de Argentina S.A.C.e I. Johnson & Johnson de Colombia S.A. Johnson & Johnson de, S.A. de C.V. Johnson & Johnson de Venezuela, S.A. Johnson & Johnson del Peru S.A. Johnson & Johnson do Brasil Industria E Comercio de Produtos Para Saude Ltda. Johnson & Johnson European Treasury Company Johnson & Johnson (Egypt) S.A.E. Johnson & Johnson Finance Limited Johnson & Johnson Financial Services GmbH Johnson & Johnson Gesellschaft m.b.h. Johnson & Johnson GmbH Johnson & Johnson Group Holdings G.m.b.H Johnson & Johnson Hellas S.A. Johnson & Johnson Hemisferica S.A. Johnson & Johnson Holding GmbH Johnson & Johnson (Hong Kong) Limited Johnson & Johnson Inc. Johnson & Johnson Industrial Ltda. Johnson & Johnson International Financial Services Company Israel Hong Kong Argentina Colombia Venezuela Peru Brazil Egypt Austria Greece Puerto Rico Hong Kong Canada Brazil 6

7 Johnson & Johnson Kft. Johnson & Johnson K. K. Johnson & Johnson Korea, Ltd. Johnson & Johnson Limitada Johnson & Johnson Limited Johnson & Johnson Limited Johnson & Johnson LLC Johnson & Johnson Luxembourg Finance Company Sarl Johnson & Johnson Management Limited Johnson & Johnson Medical B.V. Johnson & Johnson Medical () Ltd. Johnson & Johnson Medical GmbH Johnson & Johnson Medical Holding S.p.A. Johnson & Johnson Medical Korea Limited Johnson & Johnson Medical Limited Johnson & Johnson Medical, S.A. de C.V. Johnson & Johnson Medical NV Johnson & Johnson Medical Products GmbH Johnson & Johnson Medical (Pty) Limited Johnson & Johnson Medical Pty Ltd. Johnson & Johnson Medical (Shanghai) Ltd. Johnson & Johnson Medical S.p.A. Johnson & Johnson Medical (Suzhou) Ltd. Johnson & Johnson (New Zealand) Limited Johnson & Johnson Nordic AB Johnson & Johnson Pacific Pty. Limited Johnson & Johnson Pakistan (Private) Limited Johnson & Johnson (Philippines), Inc. Johnson & Johnson Poland Sp. z o.o Johnson & Johnson, Prodaja medicinskih in farmacevtskih izdelkov, d.o.o. Johnson & Johnson (Proprietary) Limited Johnson & Johnson Pte. Ltd. Johnson & Johnson Pty. Limited Hungary Japan Korea Portugal India Russia Luxembourg Korea Austria South Africa New Zealand Pakistan Philippines Poland Slovenia South Africa Singapore 7

8 Johnson & Johnson S.A. Johnson & Johnson SDN. BHD. Johnson & Johnson S.p.A Johnson & Johnson, s.r.o. Johnson & Johnson, s.r.o. Johnson & Johnson Swiss Finance Company Limited Johnson & Johnson Taiwan Ltd. Johnson & Johnson (Thailand) Ltd. Johnson & Johnson Vision Care () Limited Johnson & Johnson Vision Care (Shanghai) Ltd. Laboratoires Polive S.N.C. Laboratoires Vendome, SAS Latam International Investment Company Latam Properties Holdings Lifescan Canada Ltd. Lifescan Scotland Limited McNeil AB McNeil Comm. VA McNeil Consumer Healthcare GmbH McNeil Consumer Healthcare, S.L.U. McNeil Denmark ApS McNeil Esbjerg ApS McNeil GmbH & Co. ohg McNeil Healthcare (UK) Limited McNeil Iberica S.L.U. McNeil Limited McNeil Manufacturing Pty Ltd McNeil, S. de R.L. de C.V. McNeil Products Limited McNeil Sante Grand Public McNeil SAS McNeil AB Medos International Sarl Spain Malaysia Czech Republic Slovakia Taiwan Thailand Canada Spain Denmark Denmark Spain 8

9 Medos Sarl OBTECH Medical Sarl OMJ OMJ Manufacturing Ortho-Clinical Diagnostics Ortho-Clinical Diagnostics GmbH Ortho-Clinical Diagnostics K.K. Ortho-Clinical Diagnostics NV Ortho-Clinical Diagnostics S.A.S. P.T. Johnson & Johnson Indonesia Shanghai Johnson & Johnson Pharmaceuticals, Ltd. Tasmanian Alkaloids Pty. Ltd. Tibotec Pharmaceuticals Tibotec-Virco Comm. VA Tibotec-Virco Virology BVBA Turnbuckle Investment Company Vania Expansion, S.N.C. Xian-Janssen Pharmaceutical Ltd. Japan Indonesia 9

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