ROOM B 16.00-18.00 OPENING CEREMONY



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17 th September 2015 16.00-18.00 OPENING CEREMONY Introduction President of the Polish Pharmacological Society professor Marek Droździk Lecture in progress 50 years of the Polish Pharmacological Society Opening lecture - SPONSORED by BRITISH PHARMACOLOGICAL SOCIETY Chairperson: Prof. Marek Droździk (Pomeranian Medical University, Szczecin, Prof. Steve Alexander (School of Biomedical Sciences, University of Nottingham) The endocannabinoid system as a nexus of signalling complexity 20.00 Welcome Reception 18 th September 2015 ROOM A 8.30-9.00 POSTER SESSION 9.00-9.45 Plenary lecture Chairperson: Prof. Władysław Lasoń (Polish Academy of Sciences, Krakow, Prof. Stanisław J. Czuczwar (Medical University in Lublin, Caffeine and other methylxantine derivatives are they dangerous to patients with epilepsy? 12.00-12.30 Coffee braek 14.30-15.30 Lunch time 10.00-12.00 (oral presentation in progress) 12.30-14.30 (in progress)

15.30-16.15 Plenary lecture - SPONSORED BY FEDERATION OF EUROPEAN PHARMACOLOGY SOCIETIES Chairperson: Prof. Marek Droździk (Pomeranian Medical University, Szczecin, Prof. Werner Siegmund (Center of Drug Absorption and Transport, Greifswald University) - The route of drugs to their place of action 18.30-19.00 Coffee Break 20.00 Banquet 16.30-18.30 (in progress) 10.00-12.00 PROGRESS IN EPILEPSY AND ANTIEPILEPTIC DRUGS Chairpersons: Prof. Stanisław J. Czuczwar (Medical University in Lublin, Dr Roman Chwedorowicz (Institute of Rural Health, Lublin, 1. Psychiatric co-morbidities in early onset epilepsy. Animal experience Hana Kubova (Czech Academy of Science, Prague, Czech Republic) 2. Drug - resistant epilepsy from the clinical point of view Barbara Błaszczyk (High School of Economics, Law and Medicine, Kielce, 3. mirna in models of acquired epilepsy Katarzyna Łukasik (The Nencki Institute of Experimental Biology, Warsaw, 4. Drugs influencing adenosine receptors potential antiepileptics? Pavel Mares (Czech Academy of Science, Prague, 12.00-12.30 Coffee Break

12.30-14.30 GLUTAMATE METABOTROPIC RECEPTORS AND CNS DISORDERS Chairpersons: Prof. Andrzej Pilc (Institute of Pharmacology, Polish Academy of Sciences, Krakow, Prof. Małgorzata Filip (Institute of Pharmacology Polish Academy of Sciences, Krakow, 1. Chemical Biology at Lundbeck: enhancing CNS drug discovery research Dario Doller (Lundbeck Research USA) 2. Group III mglurs in brain and periphery: implications for visceral pain Anna Golubeva (University College Cork, Ireland) 3. The mechanism of antipsychotic-like action of the mglu receptor activators: focus on GABAergic signaling Joanna Wierońska (Institute of Pharmacology, Polish Academy of Sciences, Krakow, 4. Alterations in brain mglur5 and D2 receptor density during MDMA abstinence in different living conditions in rats Małgorzata Frankowska (Institute of Pharmacology, Polish Academy of Sciences, Krakow, 5. Cocaine induced dysregulation in metabotropic glutamate receptors expression in rat brain areas Lucyna Pomierny-Chamioło (Faculty of Pharmacy, Jagiellonian University, Medical College, Karakow, 14.30-15.30 Lunch time 16.30-18.30 NEUROTOXICITY AND NEUROPROTECTION Chairpersons: Prof. Lucyna Antkiewicz-Michaluk (Polish Academy of Science, Krakow, Prof. Richard Kostrzewa (East Tennessee State University, USA) 1. Monoaminergic system interaction in neurotoxicicty Richard Kostrzewa (East Tennessee State University, USA) 2. Nerotoxicity of fluorine Dariusz Chlubek (Pomeranian Medical University in Szczecin,

3. Mechanisms of calcium imbalance in tetrabromobisphenol A induced neurotoxicity Jerzy Lazarewicz (Mossakowski Institute in Warsaw, 4. New perspectives for therapeutic use of endogenous amines, 1MeTIQ. Behavioral and biochemical studies Agnieszka Wąsik (Institute of Pharmacology, Polish Academy of Sciences, Krakow, 18.30-19.00 Coffee Break 20.00 Banquet 19 th September 2015 ROOM A 8.30-9.30 POSTER SESSION 9.30-10.15 Plenary lecture Chairperson: Prof. Władysław Lasoń (Polish Academy of Sciences, Krakow, Assoc. Prof. Małgorzata Kajta (Department of Experimental Neuroendocrinology, Institute of Pharmacology, Polish Academy of Sciences, Krakow, - Pathomechanisms of xenobiotic action in the nervous system 10.30-11.00 Coffee Break 11.00-13.30 MOLECULAR MECHANISMS OF XENOBIOTIC INDUCED EFFECTS Chairpersons: Assoc. Prof. Małgorzata Kajta (Institute of Pharmacology, Polish Academy of Sciences, Kraków,, Assoc. Prof. Anna K. Wójtowicz (University of Agriculture, Kraków, 1. Risks related to exposure to environmental pollutants Anna Wójtowicz (University of Agriculture, Kraków, 2. Neurodevelopmental effects of nonylphenol Ewa Litwa (Institute of Pharmacology, Polish Academy of Sciences, Kraków,

3. Impact of triclosan on apoptotic processes in neuronal cells Konrad Szychowski (University of Agriculture, Kraków, 4. Mechanism of neurotoxic action of the pesticide DDT metabolite Agnieszka Wnuk (Institute of Pharmacology, Polish Academy of Sciences, Kraków, 5. Neuroprotective effects of phytoestrogens and selective modulators of nuclear receptors Joanna Rzemieniec (Institute of Pharmacology, Polish Academy of Sciences, Kraków, 11.00-13.30 SAFETY AND OPIMIZATION OF PHARMACOTHERAPY prepared in cooperation with the POLISH CLINICAL PHARMACOLOGY AND THERAPY SOCIETY Chairpersons: Prof. Anna Jabłecka (Medical University in Poznan,, Prof. Anna Wiela-Hojeńska (Medical University in Wrocław, 1. Therapeutic drug monitoring in optimization of antibiotic administration Anna Wiela-Hojeńska, Magdalena Hurkacz, Ewa Jaźwińska-Tarnawska (Medical University in Wrocław, 2. Pharmacogenetics in transplantation Mateusz Kurzawski Pomeranian Medical Uniwersity in Szczecin, 3. Pharmacovigilance in Poland present and future Daria Schetz (Medical University in Gdańsk, 4. Clinical significance of CYP450 polymorphism on the efficacy and safety of treatment of hypertension Anna Wojtczak, Mariola Rychlik-Sych, Małgorzata Barańska, Jadwiga Skrętkowicz (Medical University in Łodz, 5. The safety of NSAIDs in geriatric population - analysis of Regional Centre for Monitoring Adverse Drug Reactions in Poznan (ROMDNL) Anna Jabłecka (Medical University in Poznan, 14.00 Lunch time 13.30-14.00 CLOSING CEREMONY