1962 Hematology 1982 FRCPath 1983 FRCP\



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CURRICULUM VITAE NAME Lucio Luzzatto DATE OF BIRTH September 28, 1936 PLACE OF BIRTH Genova, Italy NATIONALITY Italian PRESENT POSITION 2005- Scientific Director, Istituto Toscano Tumori, Via Taddeo Alderotti 26N, 50139 Firenze, Italy Phone +39 055 438 5213 Fax +39 055 438 5252 e-mail: lucio.luzzatto@ittumori.it LICENSURE 1995 New York State Lic #198633 1974 United Kingdom 1974 Nigeria 1960 Italy BOARD CERTIFICATION 1962 Hematology 1982 FRCPath 1983 FRCP\ EDUCATION Maturità Classica, Liceo D'Oria, Genova, Italy, 1953 University of Genova Medical School M.D., Genova, Italy, 1959 Libera Docenza in Biochemistry, Min. of Education, Italy, 1968 Postdoctoral Training Cassa di Risparmio di Genova Fellow, Department of Biochemistry, University of Genova, 1959 Assistant, Department of Biochemistry, University of Genova, 1960-61 Assistant, Department of Infectious Diseases, Ospedale S. Martino, Genova, 1960-62 Fellow in Haematology, Department of Medicine, College of Physicians & Surgeons, Columbia Presbyterian Hospital, New York, 1963-64 Lecturer in Haematology, in charge of Blood Transfusion Unit Department of Pathology, University of Ibadan, Ibadan, Nigeria, 1964-67 1

POSITIONS AND APPOINTMENTS Senior Lecturer in charge of Sub-Department of Haematology, University of Ibadan, Ibadan, Nigeria, and Consultant Haematologist, UCH, Ibadan, Nigeria, 1967-68 Professor of Haematology (from 1970 Head of Department) University of Ibadan, Ibadan, Nigeria, 1968-74 Director, International Institute of Genetics and Biophysics, CNR, Napoli, Italy, 1974-81 Professor of Haematology (University of London), and Director of Haematology Department, Royal Postgraduate Medical School, London; Consultant Haematologist, Hammersmith Hospital, 1981-94 Honorary Director, MRC/LRF Leukaemia Unit, 1987-93 Chairman, Department of Human Genetics, Courtney Steel Chair, Attending Physician in Genetics and Hematology, Member of the Cell Biology and Genetics Programme, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center; Professor of Medicine and Human Genetics, Cornell University Medical College, New York, NY, USA, 1994-2000 Scientific Director, National Institute for Cancer Research, Genova, Italy, 2000-2004 Professor of Haematology, DOBIG, University of Genova, Genova, Italy 2002-2006 Professor of Haematology, University of Florence, Firenze, Italy 2006-2008 HONORARY DEGREES Laurea ad honorem in Pharmacy, University of Urbino, Italy, 1990 DSc, University of Ibadan, Nigeria, 1998 Laurea ad honorem in Medicine, University of Patras, 2006. SCIENTIFIC AND MEDICAL SOCIETY MEMBERSHIPS International Society of Haematology President, University College Hospital, Ibadan, Medical Society Foundation member and first President-elect, 1968-70 Nigerian Society for Haematology and Blood Transfusion; Founding President, now honorary member, 1968-present Expert Panel on Abnormal Haemoglobins and Thalassemia of the International Committee on Standardization in haematology, 1972-81 Italian Association of Genetics (President), 1979-81 Executive Council, Italian Society of Haematology, 1977-80 2

European Molecular Biology Organization (EMBO), Active British Society for Haematology, Active American Society of Haematology, Honorary member Human Genome Organization (HUGO), Active American Association of Physicians Chairman - Ethics Committee American Society for Gene Therapy (1997-2000) American Society of Human Genetics President, Federazione Italiana Scienze della Vita, 2008-2010 VISITING APPOINTMENTS AND NAMED LECTURES (partial list) Visiting Scientist for one month at the Department of Human Genetics, University of Leiden, NL,1966 Visiting Scientist for seven months to the Department of Microbiology, Washington University Medical School, St. Louis, MO, USA, 1967 Visiting Professor for one month at the Department of Medicine, Makerere University, Kampala, Uganda, 1969 Visiting Professor for two weeks at the Department of Haematology, Mahidol University, Bangkok, Thailand, 1972 Visiting Professor for two weeks at the Faculty of Medicine, University of Nigeria, Enugu, 1974 Henry M. Stratton Lecture, XV International Congress of Haematology, 1974 Cari Harford Visiting Professor, Washington University Medical School, St. Louis, MO, USA, 1983 British Exchange Professor, Department of Medicine, UCLA, Los Angeles, CA, USA, 1987 Ham-Wasserman Lecture, American Society of Haematology, San Francisco, CA, USA, 1988 Oliver-Sharpey Lecture, Royal College of Physicians, 1988 Visiting Professor, Department of Medicine, University of Michigan, Ann Arbor, MI, USA, 1989 Adolfo Ferrata Lecture, Italian Society of Haematology, Rome, Italy, 1989 Visiting Professor, Toronto General Hospital, Toronto, Canada, 1990 Visiting Professor, University of Modena, Italy, 1991 Visiting Professor, University of Naples, Italy, 1992 Visiting Professor, Department of Pathology, University of Alberta, Edmonton, Alberta, Canada, 1994 Fifth William C. Maloney Lecture Brigham and Women's Hospital, Boston, MA, 1998 3

Lilly Lectures - Royal College of Physicians London and Sheffield, UK, 1999 Josè Carreras Lecture - European Haematology Association, Firenze, 2002 HONORS AND AWARDS (partial list) Livierato Prize, University of Genova, 1957 Pasetto Prize, University of Genova, 1958 Istituto Nazionale Assistenza Infortuni sul Lavoro Prize, 1960 Ministero della Pubblica Istruzione Fellow, 1962 Fulbright Senior Fellow, 1967 Pius XI Medal, 1976 Sanremo International Prize for Human Genetics, 1982 International Chiron Award for Biomedical Research, 1995 Premio Napoli, 1995 Nigerian Society of Haematology and Blood Transfusion: 25 th Year Jubilee Lecture, 1997 University of Ibadan, Nigeria, 1998 Premio Pier Camillo Beccaria, Associazione Angela Serra, Modena, Italy, 1999 Premio Liguria, 2000 James Blundell Award, British Society of Blood Transfusion, 2001 Foreign Member, American Academy of Arts and Sciences, 2004. OTHER Director, WHO Regional Reference Centre (Africa) for glucose-6- phosphate dehydrogenase, 1967-74 Member (Rapporteur) of a WHO Scientific Group, 1971 Chairman of the Organizing Committee for the first Advanced Seminar in Haematology for Africa, Ibadan Nigeria, 4-19 August, 1972 Director of WHO Collaborative Centre for human glucose-6-phosphate dehydrogenase, 1976-81 Member (Chairman from 1983) of Steering Committee of Scientific Working Group on Biomedical Sciences, Special Programme on Tropical Diseases, WHO, 1978-86 Member of MRC Cell Board Grants Committee, 1982-86 Clinical Panel of Wellcome Trust, 1986-88 Member of MRC Human Genome Mapping Grants Committee, 1989-91 Pathology Panel of Universities Funding Committee, 1992 4

Appointed by the World Health Organization (WHO) to serve in a Scientific Group for the standardization of techniques for the study of glucose-6- phosphate dehydrogenase, 1996 International Outreach Ad Hoc Committee, American Society of Hematology Member National Cancer Advisory Board - Ministry of Health, Italy, 2000 Member National Advisory Board on Stem Cell Research - Ministry of Health, Italy, 2000 Representative of Ministry of Health in National Research Programme of Italic Government, 2002. Member of International Advisory Board of the Institute of Genetic Chemistry and Laboratory Medicine, Nigeria, 2007 Member of Scientific Committee of the Programma straordinario oncologico a carattere nazionale per l anno 2006, 2007 Member of Scientific Committee of Associazione contro il melanoma, 2007 Member of ISPO Scientific Committee, 2007 President of International Scientific Review Board of Fondazione Internazionale di Ricerca in Medicina Sperimentale, 2007-2009 Member of Advisory Board, Tuscan Region, 2008 Member of Scientific Committee of OECD Review of Region Innovation, 2008 Member of the HuGeF Scientific Committee, 2008 2009 Member of the International Advisory Board of Academia Engelberg, 2009 Member of National Oncology Committee, Italian Ministry of Health, 2008 2009 Member of Scientific Committee of Fondazione Alfredo, Aurelio e Leonida Alitti Onlus, 2010 Member of the Scientific Committee of the 14 th Biotechnology Symposium and Exhibition, 2010 International Peer Reviewer for NIHR Programme Grants for Applied Research (NHS Blood and Transplant), 2010. LANGUAGES Spoken: Italian, English, French, German Written: Italian, English SOCIAL SECURITY # 098-36-9673 MARITAL STATUS SPOUSE'S NAME: CHILDREN Married Paola Caboara Luzzatto Stefano & Fatima 5

MILITARY SERVICES: Medical Officer, Italian Army - 1960-61; now in Reserve Armed Forces Medical Services 6