PRESENTATION Adrián Gutiérrez Science and Technology Counsellor, Embassy of Spain to India Chief Representative of CDTI India and Southeast Asia, Secretariat of State for Research, Development and Innovation, Ministry of Economy and Competitiveness adrian.gutierrez@cdti.es
Index 1. SPAIN - STI Overview and indicators. 2. Highlights on the Participation of SPAIN in EU FP7 3. Biotech Sector in Spain 4. Indo-Spanish Programme for Technological Cooperation with India in Biotechnology
1. Spain - STI Overview and Indicators GERD in $ bn (PPP) 25 20 15 10 5 0 8.4 9.8 0.9% 10.9 11.8 2012 = 1.3 % 13.3 1.1% 1.0% 1.0% 16.0 18.3 20.4 20.4 20.2 19.8 1.4% 1.4% 1.4% 1.3% 1.3% 1.5% 1.2% 1.1% 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 3.0% 2.5% 2.0% 1.0% 0.5% 0.0% % GERD/GDP In ten years GERD has more than doubled CAGR of 8.9% from 2001-2011 Financial crisis causing deceleration in last 3 years 2013 positive forecast for R&D funding. Source: OECD Main Science and Technology Indicatos 2013/01
1. Spain STI Overview Indicators Increasing competitiveness High implication of private sector with escalating competitiveness 100% 0.2% 9% 28% % GERD by execution 75% 50% 25% 52% Non profit private organizations Higher Education Private Sector Government 6% 3% 0% 19% 0% FM II FM III FM IV FM V FM VI FM VII Investment (as % of total contribution to UE budget) Return (as % of assigned budget on competitive calls) Source: Spanish Science & technology Indicators 2012. National R&D Observatory, FECYT Source: Spanish Science & technology Indicators 2012. National R&D Observatory, FECYT FM: Framework programme (European funding programme)
1. Spain STI Overview and Indicators R&D INTENSITY: Spain s R&D intensity has grown from 0,9% GDP in 2000 to 1.36% in 2012. SCIENTIFIC PUBLICATIONS AND IMPACT: 10th Scientific Power in the world by number of publications and 14th scientific power in terms of citations. 12% of European scientific production 15% of Spanish scientific production in the top ten percent of best scientific production worlwide. 78% of the scientific publications published in Spain lead by Spanish principal investigator. Exponential growth in number of scientific publications (7.1%) during 1996-2010; way beyond average growth of Western Europe and North America. R&D PERSONNEL: 208,831 (12.1 per thousand labour force; 60.7% researchers).
1. Spain STI Overview and Indicators PATENT APPLICATIONS (2012) : 262,834 patent applications Spain = 0.33% of worlwide number of approved triadic patents. HIGH TECH EXPORTS (2012): 11.39 million euros (9% annual growth) SPAIN ranks 27 TH out of 143 countries on the Global Innovation Index 2014 INSEAD. INNOVATIVE BUSINESS SECTOR 18,000 firms actively involved in innovation in their business models Spain ranks 13 among the world's top 2,000 R&D investing firms. Companies mainly active in the ICT services sector,the pharma and biotech sectors, energy and industrial engineering sectors. EQUIPPED WITH LATEST SCIENCE INFRASTRUCTURES
1. Spain STI Overview and Indicators *Supercomputer Mare Nostrum *PSA Solar Platform of Almería *Spanish led Great Telescope of La Palma *Synchrotron Alba
1. Spain STI Overview and Indicators PUBLIC RESEARCH BODIES
Index 1. SPAIN - STI Overview and indicators 2. Highlights on the Participation of SPAIN in EU FP7 3. Biotech Sector in Spain 4. Indo-Spanish Programme for Technological Cooperation with India in Biotechnology
2. Highlights on the Participation of SPAIN in EU FP7 Participation in the EU 7th Framework Programme for R&D European funding 6th FP: accumulated return 7th FP: accumulated return 6,5% 8,2% 7th FP (2007-2013*): Grants of 3.200 M Support to universities, R&D companies, technological centers and other players The FP is one of the largest sources of project financing in Europe and in Spain
2. Highlights on the Participation of SPAIN in EU FP7 *PROVISIONAL RESULTS 6 TH FP7 MONITORING REPORT (2007-2013) 6 th LARGEST RECIPIENT UNDER EU FP7 Return of 8.3% of the total budget allocated to EU 27 Increase of leadership of Spanish entities in consortia from 6,3% (FP6) to 10.7% (FP7). 3,200 MILLION EUROS GRANTS FOR SPANISH PARTICIPATING ENTITIES. TOTAL OF +7,500 SPANISH ENTITIES PARTICIPATED AND SUBMITTED PROPOSALS UNDER THE DIFFERENT FP7 CALLS / SUCCESS RATE OF SPANISH ENTITIES OF 19.2%. 2,600 SPANISH ENTITIES PARTICIPATE IN SELECTED PROJECTS FOR FUNDING. 1,682 out of the total are companies and 75% SMEs. Participate in 6,000 activities. Participate in 3,207 R&D projects, out of which 745 are lead by Spanish principal investigators.
2. Highlights on the Participation of SPAIN in EU FP7 *PROVISIONAL RESULTS 6 TH FP7 MONITORING REPORT (2007-2013) SPANISH ENTITIES BY RETURN: 31.4% Companies 22.8% Universities 14.7% Public Research Institutions 11.1% Research Associations 11% Technology Centres TOP THEMATIC AREAS IN THE COOPERATION PROGRAMME, BY RETURN: ICT (610.8 millions of euros) NANOSCIENCES, NANOTECHNOLOGY, MATERIALS, NEW MANUFACTURING TECHNOLOGIES (366.3 millions of euros). HEALTH (267.4 millions euros).
Index 1. SPAIN - STI Overview and indicators 2. Highlights on the Participation of SPAIN in EU FP7 3. Biotech Sector in Spain 4. Indo-Spanish Programme for Technological Cooperation with India in Biotechnology
3. Biotech Sector in Spain A young sector, 15 years old. Internationalization, is part of its DNA. Success depends on the capacity to export. Crucial: Joint Projects and Technology Exchange Agreements. SPAIN 350% accumulated growth rate in the last 4 years. Key player in R&D, spin-offs, research and collaboration. BIOTECH: a key sector in the knowledge-based economy
3. Biotech Sector in Spain 2012 *Source: ASEBIO Report 2013 Number of Enterprises: Number of Personnel Employed EB+EIB: 202,976 3,070 (625 EB+2,445 EIB) Estimated turnover EB+EIB: 80.312 billion euros Internal Expenditures on R&D: 523,344 million euros (11.2% increase in comparison to 2009 levels) Enterprises related to human health: 55 % Enterprises related to Agro-Food: 32.3% Enterprises related to industrial processing: 11% *EB Biotechnology Enterprise *EIB Industrial, commercial or services enterprise with interests, developments and products in biotechnology
3. Biotech Sector in Spain SNAPSHOT: KEY OECD BIOTECH INDICATORS (2012) 2nd top OECD country, by number of Biotech firms. 3rd OECD country in terms of R&D public expenditure in 2010 (representing a total of 14,1% of total public R&D expenditure). 8th OECD country in terms of total biotech expenditure of the business sector investment stood at 794.1 M (7.6% of total R&D investment of national companies). 1,79% share (India 1,11%) of the total number of patents filed by biotech companies under the Patent Co-operation Treaty (PCT 2008 2010)
3. Biotech Sector in Spain Contribution to GDP 2012 (%) 1.6 Contribution to GDP of EB + EIB(%) 7.8 Contribution to GDP (%) Predicted contribution to GDP (%) Employment Predicted employment
3. Biotech Sector in Spain AGRICULTURE ANIMAL HEALTH FOOD ENVIRONMENT HUMAN HEALTH
3. Biotech Sector in Spain PROFILE OF BIOTECH ENTERPRISES (EB) IN SPAIN Between 10 and 20 employees. Over 80% of the staff are university graduates. Over 25% of the staff devoted to R&D. Less than five years of activitiy. Located mostly in Madrid, Barcelona, Andalucía, País Vasco and Valencia. Linked to prestigious public research institutions.
3. Biotech Sector in Spain 8 BIOREGIONS
3. Biotech Sector in Spain SOME SUCCESS STORIES 2000: Pfizer invested 12 M in its European Biometric Centre, with support functions to the rest of Europe and USA. 2002: Abengoa signed a 35.5 M USD R&D Agreement with the US Department of Energy. 2002: Lilly opened its research centre for medicinal chemistry (one of the biggest in the world representing an investment of 20 M ) 2003: Serono concentrates its global growth hormone production in Spain. 2005: GSK opens Linked its research centre for tropical diseases in Spain. 2009: Genzyme sets up a sales office in Madrid and a warehouse for domestic distribution. 2011: Celgene opens its first research centre outside the USA in Seville. The Celgene Institute for Translational Research Europe (CITRE) plans to focus on advanced therapies and regenerative medicine.
3. Biotech Sector in Spain HEALTH & BIOTECHNOLOGY SPAIN S TECHNOLOGICAL STRENGTHS (I) Highly competitive industry at the global markets Biotech sector: 2 nd OECD country by number of biotech firms / 3 rd by R&D expenditures performed by the public sector (OECD Biotechnology Indicators 2012). Strong spin-out culture Global leader in plasma derived products and therapies (Grifols) 5 th worldwide in exports of health technologies 5 th ranked country in Europe in number of clinical analysis Spanish model for management of organ transplant considered an international reference. 2.5% of scientific publications in biotechnology and pharma are produced in Spain (British Royal Society, 2012) 4 th Nano biotechnology Scientific production in the world Barcelona the 2 nd Nano biotech city (1 st Boston) 3 rd worldwide in agro biotechnology and 5 th in biochemistry and molecular biology Top infrastructures and scientific excellence CNIO: number one cancer research centre, as per number of scientific publications and their impact. Development of first malaria vaccine headed by Spanish scientist Pedro Alonso (CRESIB).
3. Biotech Sector in Spain HEALTH & BIOTECHNOLOGY SPAIN S TECHNOLOGICAL STRENGTHS (II) Big network of science parks (bioclusters) Main technologies Oncology: Advancell, GP Pharm, Ingenasa, Pharmamar, IUCT, Lipopharma, Entrechem, Orizon Genomics. Cardiology and Neurological: Neuron Pharma, Sanifit Oftalmic Optics: Indo, Instituto Fernández Vega, Centro Barraquer, Sylentis, Proretina Therapeutics, Bioftalmik. Biotech diagnosis, biomarkers, nanomedicine: Oryzin Genomics, Sistemas Genómicos, AB Biotics, Genomica, Biobide, Pangea Biotech, Genetadi Biotech, Aromics, Nanotherapy, Nanoinmunotech, Animal Health: Bionaturis, Ingenasa. Bioinformatics: Integromics, Noray Bio, Biomol Informatics Reproductive technologies (IVI). Regenerative medicine, Cell and Gene therapy: Tigenics (former Cellerix) Biofuels: Abengoa, Repsol E-Health Management and Model - Pioneer in applying solutions such as electronic prescription and digital medical records (Indra, Telefónica, Oesia, Everis). Development of drugs of marine origin (Pharmamar).
3. Biotech Sector in Spain INSTITUTIONS SUPPORTING THE SECTOR IN SPAIN : PROMOTING VALUE CREATION THROUGH KNOWLEDGE ASEBIO is the Spanish Asociation of Biocompanies ASEBIO belongs to and is supported by EUROPABIO, and is a part of CEOE and SEBBM SPANISH TECHNOLOGY PLATFORMS www.asebio.com Biotechnology Markets www.medicamentos-innovadores.org Nanomedicine www.nanomedspain.net Innovative Medicines www.medicamentos-innovadores.org Plant Biotechnology www.invegen.org Animal Health www.vetmasi.es Biomass www.bioplat.org
Index 1. SPAIN - STI Overview and indicators 2. Highlights on the Participation of SPAIN in EU FP7 3. Biotech Sector in Spain 4. Indo-Spanish Programme for Technological Cooperation with India in Biotechnology
4. SPANISH Programme for Technological Co-operation with INDIA in Biotechnology TECHNOLOGICAL CO-OPERATION Centre for the Development of Industrial Technology Created in 1977 Public Entity (Ministry of Economy and Competitiveness) Business innovation financing agency Focal point for the promotion of technological innovation High national and international prestige Enhance Spanish companies competitiveness and internationalization through innovation
4. SPANISH Programme for Technological Co-operation with INDIA in Biotechnology TECHNOLOGICAL CO-OPERATION Direct funding to R&D projects (million ) 2000 1000 368 461 896 1.205 917 1.251 1.250 1.380 0 2004 2005 2006 2007 2008 2009 2010 2011 Number of R&D projects approved by CDTI 2500 2000 1500 1000 500 0 2.315 2.224 1.703 779 801 1.063 1.154 1.224 2004 2005 2006 2007 2008 2009 2010 2011
4. SPANISH Programme of Co-operation with INDIA in Biotechnology TECHNOLOGICAL CO-OPERATION RTDI funding Evaluation and funding: Individual R&D projects National Cooperation R&D projects Innovation projects Internationalization Reports towards tax exemption Support to the creation and consolidation of new technology based companies NEOTEC NEOTEC Venture Capital INNVIERTE RTDI internationalization Support to technology transfer: Foreign network Technology Cooperation: Eureka, Iberoeka, Eurostars, Eu ropean Framework Programme International Technology Promotion Aeronautics, Space and Industrial Returns Programmes Aerospace RTDI Technological supplies: CERN, Hispasat, Eumetsat
4. SPANISH Programme for Technological Co-operation with INDIA in Biotechnology TECHNOLOGICAL CO-OPERATION R+D+I company process Precompetitive Research Technical risk Technological Development Industrial Innovation Technology Internationalization CDTI project type Funding intensity Industrial Research Research center collaboration Development New products/processes development Innovation Technology update International Technological Promotion Technology transfer and promotion RTDI FUNDING
4. SPANISH Programme for Technological Co-operation with INDIA in Biotechnology TECHNOLOGICAL CO-OPERATION Canada - Canadeka National Reseach Council (NRC) Technical risk Korea Korea Spain Innovating (KSI) Korea institute for Advancement of Technology (KIAT ) Bilateral programs Different cultures = different solutions Tailor-made agreements JSIP Japan Japan Spain Innovation program (JSIP) South Africa South Africa Spain Innovating (SASI) Technology Innovation Agency (TIA ) SASI India India Spain Innovation Program India India Spain Innovation - Technology Program Development Board (TDB) - Department - Technology of Biotechnology Development (DBT) Board (TDB) - Department of Biotechnology Ministry (DBT) of New and Renewable Energies (MNRE) Ministry of New and Renewable Department Energies of (MNRE) Science and Technology and Global Innovation Department and of Technoloigy Science and Alliance Technology Fund (DST/GITA) and Global Innovation and Technoloigy Alliance Fund (DST/GITA) New Energy Industrial Technology Development Organisation (NEDO) China - Chineka High Technology Industry development Center (Torch)
4. SPANISH Programme for Technological Co-operation with INDIA in Biotechnology TECHNOLOGICAL CO-OPERATION CDTI s strategy: Identification of High Relevance Countries for Spanish Companies CDTI s delegate in India since 2006 Technical risk CDTI s Institutional Agreements with India: TDB (Technology Development Board) since 2006 DBT (Department of Biotechnology) since 2011 MNRE (Ministry of Renewable Energy) since 2011 DST (Department of Science and Technology) and GITA (Global Innovation and Technology Alliance Fund) since 2013 Calls for Industry-driven R&D proposals in 2014-2015: Indo Spanish Call in Clean Technologies, ICT and Smart Cities (DST/GITA CDTI) Opened: 20/11/14 15/04/2015 NEW JOINT CALL FOR INDUSTRIAL R&D PROPOSALS TO BE ANNOUNCED BY DBT (India) and CDTI (Spain) in 2015
4. SPANISH Programme for Technological Co-operation with INDIA in Biotechnology Implementing Organizations Calls for Proposals Department of Biotechnology Ministry of Science and Technology THEMATIC AREAS: Technical generic riskcall open to collaborative R&D projects in all areas of biotechnology e.g. health biotechnology, industrial biotechnology, nano-biotechnology, agro-biotechnology, including biofuels and bioenergy, bioinformatics and biomedical engineering TYPE OF PROPOSALS: Development or substantial improvement of new products, processes or services Industry-driven and market-oriented R&D projects Joint technological co-operation projects between researchers and companies in India and companies in Spain Duration of projects: from 1 up to 3 years
4. SPANISH Programme for Technological Co-operation with INDIA in Biotechnology WHO CAN APPLY?: Minimum eligibility criteria: at least one qualified partner from India and one Technical qualified risk partner from Spain (1+1) From the Spanish side the project must necessarily be led by a company, and Collaboration with other Spanish R&D entities (research institutes, academic institutions, technology centres) is permitted From the Indian side of the consortium can either be led by a company or a research institution
4. SPANISH Programme for Technological Co-operation with INDIA in Biotechnology HOW TO APPLY? Joint R&D&I proposals must be submitted to both of the nodal agencies, DBT and CDTI Indian andtechnical Spanish risk co-applicants must elaborate a single project proposal application CDTI ISIP application http://www.cdti.es i. Preliminar Report (spanish) ii. Application Form (english) iii. Consortium Agreement (english) DBT http://dbtindia.nic.in/ i. Application Form ii. Consortium Agreement iii. Funding organisation-specific documents to be submitted to DBT
4. SPANISH Programme for Technological Co-operation with INDIA in Biotechnology WHAT CAN BE FINANCED? Technical personnel Technical risk Material costs Amortisation of assets Outsourced technical collaborations Other costs (indirect costs, audit costs)
4. SPANISH Programme for Technological Co-operation with INDIA in Biotechnology CDTI-DBT ISIP SUCCESS HISTORY (2012) N Project Code 1 IS-20120004 NATURINDIA Acronym Title Indian Participants Technical risk DEVELOPMENT OF NUTRACEUTICAL PLANTAS EXTRACTS AND FOOD SUPPLEMENTS BASED ON THE SYSTEMATIZATION OF INDIAN SYSTEM OF MEDICINE 2 IS-20120003 APTAFOOD APTAMER BASED BIOSENSING FOR THE DETECTION OF FOOD TOXINS 3 IS-20120012 FUNFRUT DEVELOPMENT OF A NOVEL PROCESS TECHNOLOGY FOR THE COMMERCIAL FREE FRUIT JUICES AND STUDY OF THE END PRODUCT FUNCTIONAL EFFECT ON LIPID ACCUMULATION NATURAL REMEDIES PVT. LTD. CENTRAL FOOD TECHNOLOGICAL RESEARCH INSTITUTE-CFTRI LOYOLA COLLEGE & TVN PRODUCTS COMPANY Spanish Participants PLANTAS MEDICINALES DE CATALUÑA, SA LABORATORIO CIFGA, SA BIOPOLlS S.L. In the frame of the referred Call, a total of 7 joint R&D project proposals were validly submitted fulfilling all the criteria laid down in the same text of the Call for Proposals within the deadline
4. SPANISH Programme for Technological Co-operation with INDIA in Biotechnology CDTI-DBT ISIP SUCCESS HISTORY (2013) N Project Code Acrony m 1 IS-20130001 TRASGLUTA MINASA 2 IS-20130002 BIORCAP Technical risk Title STREPTOMICES MOVAERENSES STRAIN OPTIMIZATION BIOSANITARY AND BIOSTIMULANTS PRODUCTS BASED ON THE COMBINATION OF MICRO-ORGANISMS AND ORGANIC STABILISED BIO-NUTRIENTS Indian Participants CLEANERGIS BIOSCIENCE PVT. LTD. JAY BIOTECH PVT. LTD. Spanish Participants BDF NATURAL INGREDIENTS, S.L. DADELOS, S.L. In the frame of the referred Call, a total of 6 joint R&D project proposals were validly submitted fulfilling all the criteria laid down in the same text of the Call for Proposals within the deadline NEW JOINT CALL FOR INDUSTRIAL R&D PROPOSALS TO BE ANNOUNCED BY DBT (India) and CDTI (Spain) in 2015
Thank you! Adrián Gutiérrez Science and Technology Counsellor, Embassy of Spain to India Chief Representative of CDTI India and Southeast Asia, Secretariat of State for Research, Development and Innovation, Ministry of Economy and Competitiveness adrian.gutierrez@cdti.es