Bill & Melinda Gates Foundation: Our Role in the Polio Eradication Initiative

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Bill & Melinda Gates Foundation: Our Role in the Polio Eradication Initiative Tim Petersen Vaccine Preventable Diseases Delivery Global Health Program November 20, 2009 Our Belief ALL LIVES NO MATTER WHERE THEY ARE BEING LIVED HAVE EQUAL VALUE 2009 Bill & Melinda Gates Foundation 2 1

Our Focus Areas 2008 Grants Summary 17% Global Development Program $462 million Global Health Program $1.8 billion 64% 19% United States Program $519 million Total 2008 grant payments: $2.8 billion 3 Our Grantmaking Process Typical Grants Help reduce the greatest inequities Advance existing strategies Catalyze momentum Leverage collaboration and partners Favor preventative approaches Produce measurable results 4 2

Global Health Strategies Percentage of 2009 Global Health Spending Polio 14% HIV 14% Advocacy 11% Malaria 9% TB 7% Neglected Diseases 7% Vaccine Preventable Diseases 7% Maternal & Newborn Health 6% Pneumonia 5% Vaccines Discovery 4% Diarrhea 5% Other areas (Nutrition, FP, Tobacco) 11% 5 Global Health: Support to the Global Polio Eradication Initiative is a top priority 2008 Bill & Melinda Gates Foundation 6 3

Rotary Inspired the Foundation Incredible fundraising Billions of children vaccinated 99% decrease in infections And help ensure continued funding and attention Through our grants we will contribute to: Increasing the chances to reach eradication more quickly and efficiently Make investments in projects that promote local solutions in polio affected countries Develop tools for a safe post eradication period $200M Challenge Is Essential "The extraordinary dedication of Rotary members has played a critical role in bringing polio to the brink of eradication.we are committed to helping reach that goal." BILL GATES 4

BMGF Polio Grants Overview 1999 2006 Silent funder of polio eradication efforts $200M 2007 11 1:1 matching grant to Rotary $100M 2008 $150M and began active role in program and advocacy work Bill Gates Trip to India 2009 $255M (including second $100M matching grant to Rotary) Polio featured din Mr. Gt Gates first annual ltt letter Bill Gates Trip to Nigeria Total: More than $680M for polio in last 10 years Funding by BMGF as Percentage of Total GPEI Funding July 2008 to July 2009 Estimate 30% BMGF 70% Other Donors Majority of our polio funding goes to WHO, UNICEF and Rotary 5

Funding by BMGF by Activity BMGF Polio Funding: 2008 09 Allocation Soc Mob & Comm, 6% Research, 6% Advocacy, 1% Surveillance & Lab, 6% Vaccine, 11% Campaign operations, 71% Key achievements Area Coverage in Nigeria Outbreak Response Surveillance & Lab Network Product Development Research Achievement % of children with 3+ doses of OPV increased from 57% to 63% Increased political commitment and oversight Funds allowed for faster response to outbreak Helped limit the spread of polio in import countries Helped maintain AFP surveillance and laboratory confirmation at a high quality Contributed to research onneedle free devices May be useful for GPEI and other immunization programs. Prioritized research with BMGF funds Establishment of Polio Research Committee Enhanced program priority of research Antivirals 6

Advocacy & resource mobilization how the foundation can help The Sultan of Sokoto & Traditional Leaders, Feb 09 Feb 2009: Abuja Communiqué by State Governors Potential future areas of investments 2010 2012 Proportion of the global financial resource requirements New initiatives that may optimize the probability of success Emphasis on improving quality of polio campaign implementation Focusing on improving coverage of children through better routine immunization program s Operational research New vaccine research Political Advocacy 7

Summary Polio is one of the highest priorities of the foundation We are committed to working with partners and donors to achieve polio eradication We will use the voice of the foundation for advocacy Our investments will be coordinated with partners to support core and new activities that will optimize probability of success Our long term efforts will be to build a sustainable immunization delivery system for polio, measles, new and under utilized vaccines The harsh mathematics of polio makes it clear: We cannot maintain a level of one thousand or two thousand cases a year. Either we eradicate polio, or we return to the days of tens of thousands of cases per year. That is no alternative at all. We don t let children die because it is fatiguing to save them. Our commitment as a foundation is to work with partners until no children die from polio. Bill Gates 16 8