Systems Chemistry II: Evolution and Systems



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RESEARCH CONFERENCES ESF-COST High-Level Research Conference Systems Chemistry II: Evolution and Systems Anna Grand Hotel Balatonfüred, Lake Balaton Hungary 18-23 October 2009 Chair: Eörs Szathmáry, Collegium Budapest, HU Vice-Chair: Dieter Schinzer, University of Magdeburg, DE www.esf.org/conferences/09332 Eörs Szathmáry, Collegium Budapest, HU www.esf.org

Final Programme Sunday 18 October Late afternoon/ early evening Registration at the COST-ESF desk 19:00-19:30 Eörs Szathmáry Collegium Budapest, HU 19:30-21:00 Dinner Welcome Note from Chair 21:00 Welcome Drinks Monday 19 October Session 1 Chair: Mauro Santos, Autonomous University of Barcelona, ES William Martin Heinrich-Heine University Düsseldorf, DE Hydrothermal Vents and the Origin of Life Günter von Kiedrowski Ruhr University Bochum, DE TBD (Replicator and Systems Chemistry) 10:40-11:10 Coffee break 11:10-12:00 Pier Luigi Luisi University of Rome, IT Chemical Aspects of Synthetic Biology James Cleaves Carnegie Institution of Washington, US What Were the Building Blocks Available for Proto-Life? The Prebiotic Small Molecule Inventory Goran Goranovic University of Southern Denmark, DK Systems Chemistry: Coupled Electron Transfer from a Nucleobase to a Lipid via a Photocatalyst 12:30-14:30 Lunch

Session 2 Chair: Chrisantha Fernando, University of Sussex, UK 14:30-15:20 Michael Yarus University of Colorado, US Chemistry and the Code 15:20-16:10 Sergei Rodin The Beckman Research Institute, US Epigenetics and Evolution: Selection for CpGs in coding regions drives evolution of homeobox genes 16:10-16:30 Coffee break 16:30-16:45 Josep Ribo University of Barcelona, ES Frank Model and Spontaneous Emergence of Chirality in Closed Systems 16:45-17:00 Addy Pross Ben Gurion University, IL Seeking the Chemical Roots of Darwinism: Bridging between Chemistry and Biology 17:00-17:15 Christoph Kuhn University Hospital Zürich, CH On an Early Theory of Life's Emergence in the Light of Future Artificial Chemical Life 17:15-17:30 Kepa Ruiz-Mirazo University of the Basque Country, ES On the Lipid-peptide Minimal Cell Scenario. 17:30-17:45 Peter Strazewski Université Claude Bernard Lyon 1, FR Of the Darwinian Advantage to be Neither too Soluble, nor too Insoluble, Neither too Solid, nor Completely Liquid Evening Lecture 18:00-19:00 Frigyes Károlyházy Eötvös University, HU The Spell of the Quantum World 19:00 Dinner Tuesday 20 October Session 3 Chair: Kepa Ruiz Mirazo, University of San Sebastian, ES Mauro Santos Autonomous University of Barcelona, ES Lack of Evolvability in Self-Sustaining Autocatalytic Networks: A Constraint on Metabolism-First Path to the Origin of Life Doron Lancet Weizmann Institute of Science, IL Selection in Populations of Lipid-World Compositional Assemblies

10:40-11:10 Coffee break 11:10-12:00 Niles Lehman Portland State University, US A Self-constructing and Autocatalytic Set of RNAs Leroy Cronin University of Glasgow, UK Dynamic Inorganic Complex Chemical Systems: From Dissipative Dynamics to Artificial Life TBC Organisation Title 12:30-14:30 Lunch Session 4 Pier Luisi Luigi, University of Rome, IT 14:30-15:20 Peter Schuster University of Vienna, AT The Role of Neutrality in Evolution. From Darwin to Present Day Molecular Biology and in Vitro Selection 15:20-16:10 Dan Tawfik Weizmann Institute of Science, IL The Evolution of New Protein Functions and Structures - a Reconstructive Approach 16:10-16:30 Coffee break 16:30-18:00 Poster session Evening Lecture 18:00-19:00 Stuart Kauffman University of Calgary, CA Collectively Autocatalytic Sets Plus Agency 19:00 Dinner & Bowling Evening Wednesday 21 October Session 5 Chair: Luc Steels, SONY Lab, Paris Ferenc Darvas ThalesNano, HU Systems Chemistry Aspects of an Emerging Field: Flow Chemistry Balázs Papp Biological Research Center Szeged, HU Systems Biology of Genetic Interactions in Yeast Metabolism 10:40-11:10 Coffee break

11:10-12:00 Dieter Schinzer University of Magdeburg (+)-Sorangicin A: Synthetic Studies and Construction of the Key Fragments Gonen Ashkenasy Ben Gurion University of the Negev, IL Kinetics and Mechanism of β-sheet Peptide Replication Pierre-Alain Monnard University of Southern Denmark, DK Biopolymerization in Self-Assembled, Structured Media 12:30 Lunch Afternoon 19:00 Dinner Thursday 22 October Half-day excursion Session 6 Chair: John Odling-Smee, University of Oxford, UK Robert Aunger London School of Hygiene and Tropical Medicine, UK Major Transitions in Big History Chrisantha Fernando University of Sussex, UK The Neuronal Replicator Hypothesis 10:40-11:10 Coffee break 11:10-12:00 Poster Session Bjørn Østman Keck Graduate Institute, US Impact of Epistasis on Evolutionary Adaptation Sijbren Otto University of Cambridge, UK Shaken, not Stirred: Spontaneous Emergence of Competing Synthetic Self- Replicators from Dynamic Molecular Networks determined by Mechanical Energy 12:30-14:30 Lunch

Session 7 Chair: Robert Aunger, London School of Hygiene and Tropical Medicine, UK 14:30-15:20 John Odling-Smee University of Oxford, UK Niche Construction and Ecological inheritance 15:20-16:10 György Kampis Eötvös University, HU Non-Aristotelian Entities: Putting Systems into Systems Chemisty and Systems Biology 16:10-16:40 Coffee break Evening Lecture 16:40-17:40 Herbert Gintis Central European University Budapest, HU Five Principles for the Unification of the Behavioral Sciences Forward Look Plenary Discussion Chair: György Kampis, Eötvös University Budapest, HU 17:40-17:43 Günter von Kiedrowski Ruhr University Bochum, DE 17:43-17:46 Mauro Santos Autonomous University of Barcelona, ES 17:46-17:49 Robert Aunger London School of Hygiene and Tropical Medicine, UK 17:49-17:52 Michael Yarus University of Colorado, US 17:52-18:10 Audience Discussion 20:00 Get-together & Conference Dinner Friday 23 October Breakfast & Departure