Prevention and Intervention



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Prevention and Intervention Archiv 2003/2004/2005/ 2007/2009 Prevention and Intervention from Molecular Biology to Clinical Perspectives The workshop will be held from September 16th 18th 2011 at the Martin-Luther-University Halle-Wittenberg, Germany The industrial countries are in a process of significant population ageing, which presents challenges especially for the health system due to increased pressure on budgets. The challenge for the future is to improve functional health among today's elderly on the one hand and to promote healthier life trajectories for future elderly cohorts on the other hand. The health care system should therefore develop from a solely repair to a more preventive system. Life-long prevention should focus on established risk behaviors like physical inactivity or unhealthy diet. Active ageing can indeed enhance quality of life as people age. Preventive interventions should slow the aging rates and, as a major goal, compress the phase of high morbidity before death. Unfortunately, the ageing rate, measured as the decline of functional capacity and stress resistance, seems to be different in every individual. Biomarkers of ageing were developed to characterize this biofunctional age and may be used to evaluate the success of preventive measures. Beside the main theme prevention and intervention - the purpose of this meeting is: to make the general public more aware of the problems of degenerative diseases, to promote greater communication among the worldwide community of individuals engaged in biomedical ageing research especially between basic scientists and clinicians and to stimulate translational research. The meeting is organized in cooperation with the German Academy of Sciences Leopoldina, the German Society of Cardiology (Working Group Heart Diseases in the Elderly), the German Society of Gerontology and Geriatrics and the German Society for Thoracic and Cardiovascular Surgery (Working Group for the Elderly Patient in Heart Surgery). The congress will continue meetings on ageing in Halle and thereby hopefully develop to a focus on ageing research in Europe. It will comprise invited talks and poster sessions. There will be no concurrent sessions. The number of participants will be restricted to 140 preferring active participants (poster presentation; poster submission deadline 31.07.2011). All questions should be directed to the main organizer, Andreas Simm. We look forward to welcoming you to Halle for a most exciting and enjoyable meeting. Cordially, Andreas Simm Main Organizer

download meeting-flyer here Friday September 16th 2011 18:00 Opening Andreas Simm download programm here Address M. Gekle, Dean of the Medical Faculty M. Gogol, German Society of Gerontology and Geriatrics R.-E. Silber, Director of the Department of Cardiothoracic Surgery Keynote lecture and Schober award Laudation Kaisu Pitkälä by Thomas E. Johnson, Boulder, USA Keynote lecture: Kaisu Pitkälä, Helsinki, Finland "Effectivness of Preventive Interventions on Older Populations" 20:00 Come Together Saturday September 17th 2011 08:00-10:00 Session 1: "What are our goals - and how can we measure them?" Chair: Kaisu Pikälä, Andreas Simm The view of a basic Scientist Tilman Grune Jena, D The view of a sports scientist Nadja Schott Stuttgart, D The view of a medical scientist Ursula Müller- Werdan Halle, D The view of a geriatrics Angelo Scuteri Rome, I 10:00-10:30 Coffee Break, Poster Session 10:30-12:30 Session 2: "Malnutrition or caloric restriction: positive or negative?" Chair: Tilman Grune, Angelo Scuteri Nopsi: a novel RNA methyl-transferase extending life span in worm and fly and its cross-talk to nutrition The obesity paradox in heart failure: Benefits of being overweight? Genetic Studies on Caloric Restriction in the Worm and in the Mouse: What Does It Tell Us? Johannes Grillari Stephan von Haehling Thomas E. Johnson Wien, A Berlin, D Boulder, USA Diets in the (oldest) old: Why? Cornel Sieber Nürnberg, D 12:30-13:30 Lunch Break 13:30-15:30 Session 3: "Sports or activity: what is effective in an aged population?" Chair: Manfred Gogol, Franklin Rosenfeldt Can you run away from aortic valve stenosis and an abdominal aortic aneurysm? Does moderate activity positively influence biological age? Volker Adams Alexander Navarrete Santos Leipzig, D Halle, D Aging and Inactivity: Strategies for Reversal LaDora Thompson Minnesota, USA Effects of a standardised physical training in frail older patients with dementia: can frailty be treated? Klaus Hauer Heidelberg, D 15:30-16:30 Poster Session / Coffee Break 16:30-18:30 Session 4: "Oxidative stress and antioxidants: re-evaluation of an old theory" Chair: George Martin, Suresh Rattan Growth hormone, methionine and aging Holly Brown-Borg Grand-Forks, USA

Epithelial stress and aging in the evolution of Lung Fibrosis Andreas Günther Giessen, D The effects of antioxidants on lifespan and disease Flint Beal New York, USA Mitochondrial theory of Aging: From mtdna mutations to protein turnover 20:00 Gala-Dinner (Moritzburg) Alexandra Trifonovic Köln, D Sunday September 18th 2011 08:30-10:30 Session 5: "Preventive interventions in clinical settings" Chair: Rolf-Edgar Silber, Ursula Müller Werdan Perspectives of preconditioning prior cardiac surgery an overview Ivar Friedrich Trier, D Preventive Implications in Cardiac Surgery of the Elderly under Gender-Specific View Sandra Eifert Leipzig, D Metabolic therapy and oxidative stress in cardiac surgery and cardiovascular disease Franklin Rosenfeldt Melbourne, AUS Ageing at heart: Too frail for intervals? Øyvind Ellingsen Trondheim, N 10:30-11:30 Poster Session / Coffee Break 11:30-11:45 Posterprice 11:45-13:45 Session 6: "Mild stress can help: the hormesis concept" Chair: Cornel Sieber, Flint Beal Hormesis: Its Significance for Toxicology, Pharmacology and Risk Assessment Edward Calabrese Amherst, USA On the Quasi-Stochastic Distributions of Major Geriatric Pathologies George Martin Seattle, USA Applying hormesis in ageing research and interventions Suresh Rattan Aarhus, DK Promoting lifespan and metabolic health by increasing oxidative stress: mitochondrial hormesis Michael Ristow Jena, D 13:45 14:15 Farewell

Keynote-speaker Kaisu Pitkälä University Helsinki, Finland Speakers (with linked CV ) Volker Adams Leipzig, D Flint Beal New York, USA Holly Brown-Borg Grand-Forks, USA Edward Calabrese Amherst, USA Sandra Eifert München, D Øyvind Ellingsen Trondheim, N Ivar Friedrich Trier, D Johannes Grillari Wien, A Tilman Grune Jena, D Andreas Günther Giessen, D Klaus Hauer Heidelberg, D Stephan von Haehling Berlin, D Thomas E. Johnson Boulder, USA George Martin Seattle, USA Ursula Müller-Werdan Halle, D Alexander Navarrete Santos Halle, D Suresh Rattan Aarhus, DK Michael Ristow Jena, D Franklin Rosenfeldt Melbourne, AUS Nadja Schott Stuttgart, D

Angelo Scuteri Rome, I Cornel Sieber Nürnberg, D Andreas Simm Halle, D LaDora Thompson Minnesota, USA Alexandra Trifonovic Köln, D

Please download the registration form here: Rich Text (rtf), can be edited zipped rtf-file (if rtf-download don't work) pdf-file and send it by fax to: Martin-Luther-University of Halle-Wittenberg Department of Cardio-Thoracic Surgery Fax: +49 (0) 345 557 5224 or by e-mail to: daniela.mueller@uk-halle.de early registration fee until 30th June 2011 100 / 50 (students) late fee: 150 / 75 (students) Notes: fee have to be paid only after confirmation of acceptance! The is complete after the registration fee has been received at our office (Central Office) or has been credited to the conference account. For invited speakers congress-fee is waived!

Prof. Dr. med. Rolf Edgar Silber Department of Cardio-Thoracic Surgery Martin-Luther-University of Halle-Wittenberg Ernst-Grube-Str. 40 D-06120 Halle/Germany Prof. Dr. rer. nat. Andreas Simm Department of Cardio-Thoracic Surgery Martin-Luther-University of Halle-Wittenberg Ernst-Grube-Str. 40 D-06120 Halle/Germany Tel: +49 (0) 345 557 2647 Fax:+49 (0) 345 557 7070 e-mail: andreas.simm@medizin.uni-halle.de Prof. Dr. med. habil. Ursula Werdan Department of Internal Medicine III Martin-Luther-University of Halle-Wittenberg Ernst-Grube-Str. 40 D-06120 Halle/Germany

The meeting takes place in the lecture rooms of the lion building. Löwengebäude Universitätsplatz 11 06099 Halle (Saale) Google Maps: link Kartengrundlage: Stadt Halle (Saale) FB Vermessung und Geodaten Kopie mit Genehmigung

recommended hotels category I I I II hotel address phone fax Dorint Charlottenhof (all speakers are in this hotel) DOMERO Hotel Rotes Ross Ankerhof City-Hotel am Wasserturm Dorotheenstr. 12 Leipziger Str. 76 single room double room booking keyword for reduced prices distance to the meeting-place +49(0)345-2923-0 +49(0)345-2923-100 79,00 104,00 Ageing 1,00 km +49 (0) 345-233 43-0 Ankerstr. 2 a +49 (0) 345-23 23-200 Lessingstr. 9 +49 (0) 345-298 20 +49 (0) 345-23 34 43-699 +49 (0) 345-23 23-219 +49 (0) 345-512 65 43 69,00 88,00 Ageing 1,07 km 65,00 85,00 Ageing 1,50 km 66,00 79,00 Ageing 0,71 km II Hotel Maritim Riebeckplatz 4 +49 (0) 345-51 01-0 II Apart-Hotel Kohlschütterstr. 5/6 +49 (0) 345-52 59-0 III Hotel Esprit Torstr. 7 +49 (0) 345-21220 - 0 +49 (0) 345-51 01-777 +49 (0) 345-52 59-200 63,00 93,00 MLU-Ageing 1,20 km 59,00 79,00 Ageing 1,25 km 43,00 62,00 Ageing 1,51 km III Hotel am Steintor Krukenbergstr. 29 +49 (0) 345-500 960 +49 (0) 345-500 9613 35,50 48,00 Ageing 0,78 km

Thank's to our sponsors (in alphabetical order)

Do you have any questions? Please contact: Prof. Dr. Andreas Simm Department of Cardio-Thoracic Surgery Interdisciplinary Centre for Ageing in Halle (IZAH) Martin-Luther-University of Halle-Wittenberg Ernst-Grube-Str. 40 D-06120 Halle/Germany Tel: +49 (0) 345 557 2647 Fax:+49 (0) 345 557 7070 e-mail: andreas.simm@medizin.uni-halle.de

Prof. Dr. Andreas Simm Department of Cardio-Thoracic Surgery Interdisciplinary Centre for Ageing in Halle (IZAH) Martin-Luther-University of Halle-Wittenberg Ernst-Grube-Str. 40 D-06120 Halle/Germany Tel: +49 (0) 345 557 2647 Fax:+49 (0) 345 557 7070 e-mail: andreas.simm@medizin.uni-halle.de Disclaimer