Gastrointestinal Tumors

Gastrointestinal Tumors CHAIRMEN: A. Carrato B. Massutí ORGANIZING COMMITTEE: A. Abad A. Antón E. Aranda A. Cervantes E. Díaz-Rubio M. Navarro J.M. Tabernero A. Carrato B. Massutí IX TTD International Symposium Molecular Biology of Digestive Turmos Colorectal cancer Gastric cancer Exocrine pancreatic cancer Under the auspices of Spanish Association for Cancer Research Premininary Program Under the auspices of Organized by Under the auspices of SOCIEDAD ESPAÑOLA DE ONCOLOGIA MEDICA

Gastrointestinal Tumors IX TTD International Symposium SCIENTIFIC COMMITTEE Alberto Abad Antonio Antón Jaffer Ajani Enrique Aranda Alfredo Carrato Andrés Cervantes Eric Van Cutsem Eduardo Díaz-Rubio David J. Kerr C.H. Köehne Roberto Labianca Bartomeu Massutí Matilde Navarro Fco. Xavier Real Philippe Rougier Alberto Sobrero José Mª Tabermero H.J. Wilke Jacques Wills ACREDITATION Participants will receive a certificate of attendance during the conference. The Symposium is accredited by the European Society for Medical Oncology (ESMO) to provide continuing medical education points to attendees. SCIENTIFIC SECRETARIAT Inmaculada Ruiz de Mena GRUPO ESPAÑOL PARA EL TRATAMIENTO DE LOS TUMORES DIGESTIVOS Paseo de la Castellana, 181 16 derecha. 28046 MADRID TEF.: 34-91-425 0607 / FAX: 34-91-425 0609 - Email: ttd@ttdgroup.org TECHNICAL SECRETARIAT Loreto Prado GRUPO 7 VIAJES C/ Pinar nº 6 bis 2º G 28006 MADRD Tel.: 34-91-564 16 26 / Fax.: 34-91-561 17 21 Email: g7pinar@grupo7viajes.com

FACULTY Albert Abad, M.D. Hospital Germans Trias i Pujol Jaffer A. Ajani, M.D. MD Anderson Cander Ctr Houston, United States Antonio Antón, M.D. Hospital Miguel Servet Zaragoza, Spain Enrique Aranda, M.D. Hospital Reina Sofía Córdoba, Spain Harry Bleiberg, M.D. Institut Jules Bordet Bruselas, Belgium Gabriel Mª Capella, M.D. Hospital Duran i Reinals (ICO) Alfredo Carrato, M.D. Hospital Universitario de Elche Elche, Alicante, Spain Andres Cervantes, M.D. Hospital Clínico Universitario Valencia, Spain Eric Van Cutsem, M.D. Universitaire Ziekenhuizen Gasthnisberg Leuven, Belgium Eduardo Díaz-Rubio, M.D. Hospital Clínico San Carlos Madrid, Spain Antonio Fojo, M.D. National Cancer Institute Bethesda, United States Jesús Garcia-Foncillas, M.D. Clínica Universitaria de Navarra Pamplona, Spain Christophe Louvet, M.D. Saint Antoine Hospital Paris, France David Kerr, M.D. University of Birmingham CRC Institute for Cancer Studies Birmingham, United Kigdom Claus-Henning Köehne, M.D. Universitâts Klinikum Carl Gustav Carus der TV Dresdem Dresden, Germany Roberto Labianca, M.D. Ospedali Reuniti Bergamo, Italy Heinz Joseh Lenz, M.D. USC Norris Cancer Center Los Angeles, United States Eugenio Marcuello, M.D. Hospital San Pablo Bartomeu Massutí, M.D. Hospital Universitario de Alicante Alicante, Spain Matilde Navarro, M.D. Hospital Duran i Reinals (ICO) Miguel Porta, M.D. IMIM Universitat Autónoma Francisco X. Real, M.D. IMIM Universitat Pompeu Fabra Philippe Rougier, M.D. Hôpital Ambroise Paré Boulogne, France Hans Joachim Schmoll, M.D. Martin Luther Universität Halle Wittenberg Halle Saale, Germany Dr. Alberto Sobrero, M.D. University of Udine Udine, Italy Jose Mª Tabernero, M.D. Hospital Vall D Hebron Dr. Hans Jochen Wilke, M.D. Kliniken Essen-Mitte Essen, Germany Jacques A. Wills, M.D. Laurentius Hospital Roermond, Netherlands

IX TTD International Symposium FRIDAY, DECEMBER 14th, 2001 16.00 Opening Ceremony Agenda 1 st SESSION: «MOLECULAR BIOLOGY OF DIGESTIVE TUMORS» Moderators: A. Abad, E. Díaz-Rubio 16.30 «Resistance mechanisms to chemotherapy. Drug development for reversal». A. Fojo 16.50 «Pharmacogenomics in Digestive Tract Tumor Treatment». H. J. Lenz 17.10 «Present and future of New Drugs designed for new treatment targets». C.H. Koehne 17.30 «Microarrays as a useful tool for research and treatment of Digestive Cancers: Utilities an pitfalls». J. García-Foncillas 17.50 Discussion: E. Marcuello, Speakers and Moderators. 18.10 Coffee Break. 2 nd SESSION: «COLORECTAL CANCER» Moderators: E. Aranda, J. M. Tabernero 18.30 «Colorectal cancer molecular pathology knowledge and its clinical aplications». G. Capella 18.50 «Controversies on colorectal cancer adjuvant treatment». E. Van Cutsem 19.10 «Controversies on locally advanced and metastatic disease management». J. Wills 19.30 «New ways and drugs for treatment». D. Kerr 19.50 Discussion: M. Navarro, Speakers and Moderators 22.00 Gala Dinner

SATURDAY, DECEMBER 15th, 2001 3 RD. SESSION «GASTRIC CANCER» Moderators: A. Cervantes, B. Massutí 09.30 «Gastric Cancer Adjuvant Treatment». P. Rougier 09.50 «Neo-adjuvant treatment and treatment for locally advanced disease». J. Ajani 10.10 «Treatment of Metastatic Gastric Cancer». H. J. Wilke 10.30 «New drugs for Gastric Cancer Treatment». H. J. Schmoll 10.50 Discussion: H. Bleiberg, Speakers and Moderators 11.10 Coffee Break 4 th SESSION: «EXOCRINE PANCREATIC CANCER» Moderators: A. Antón, A. Carrato 11.30 «Molecular Biology». F.X Real 11.50 «Molecular Epidemiology». M. Porta 12.10 «Adjuvant treatment». A. Sobrero 12.30 «Locally advanced and metastatic disease: Present approach and future perspectives». R. Labianca 12.50 Discussion C. Louvet, Speakers and moderators. 13.10 Closure

general information IX TTD International Symposium VENUE UNIVERSIDAD MIGUEL HERNÁNDEZ Aula Magna Edificio Altabix Avenida Ferrocarril s/n ELCHE (ALICANTE) SPAIN LANGUAGES The official languages of the symposium will be English and Spanish. Simultaneous translation will be available GALA DINNER (december 14th, 2001) RESTAURANTE NOU MANOLIN C/ Villegas, nº 3 Alicante HOTEL INFORMATION HOTEL HUERTO DEL CURA**** It is 10 minutes from the conference venue. Porta de la Morena, 14 03203 Elche (Alicante) www.huertodelcura.com HOTEL MILENIO*** It is 10 minutes from the conference venue. Prolongación Curtidores s/n 03203 Elche (Alicante) www.hotelmilenio.com HOTEL MELIÁ ALICANTE**** It is 30 minutes form the conference venue. All hotels are only 20 minutes from the airport. Playa Postiguet, s/n 03001 Alicante www.solmelia.com

IX TTD International Symposium Registration and Hotel Accommodation forms FAX US 34-91-5611721 three easy ways to register MAIL US GRUPO 7 VIAJES Att.: Loreto Prado C/ Pinar nº 6 bis 2º g 28006 Madrid (España) E-mail g7pinar@grupo7viajes.com

registration & accommodation IX TTD International Symposium Return the completed registration form in this program with payment to Grupo 7 Viajes. Please keep a copy for your records. To qualify for discounted registration fees, the completed registration form and full payment must be received by Grupo 7 Viajes on or before the dates specified below. Hotel rooms assigned on a first-come, first-served basis. REGISTRATION FEES: Before Oct. 30 th After Oct. 30 th Ptas. Euros Ptas. Euros Ordinary registration 109.250 658 126.500 762 ESMO & TTD members 95.000 571 110.000 662 Accompanying person 22.000 132 22.000 132 ACCOMMODATION Rates are per room and night. Breakfast and taxes included HOTEL HUERTO DEL CURA (Elche) Ptas. Euros Double room 18.959 114 Double room for single use 15.916 96 HOTEL MILENIO (Elche) Ptas. Euros Double room 15.515 94 Double room for single use 12.974 78 HOTEL MELIA ALICANTE (Alicante) Ptas. Euros Double room 18.511 112 Double room for single use 16.219 98

Registration fees can be payed by : Credit card (Visa/Amex). Checks payable To: GRUPO ESPAÑOL PARA EL TRATAMIENTO DE TUMORES DIGESTI- VOS. Bank Transfer to: GRUPO ESPAÑOL PARA EL TRATAMIENTO DE TUMORES DIGESTIVOS. Caja Madrid Sucursal Hospital Universitario Clinico San Carlos. Account nº: 2038 1594 09 6000011368. Include the attendee s full name. A photocopy of payment must be sent to the conference secretariat together with the registration form. REGISTRATION FEE INCLUSIONS Included in the registration fee are: attendance to scientific sessions, conference materials, certificate of attendance, refreshments, breaks and gala dinner listed in the program. ACCOMPANYING PERSON FEES INCLUSIONS Gala dinner. ACCOMMODATION Prices are per room and night. Breakfast and taxes included. Hotel rooms assigned on a first-come, first-served basis. REGISTRATION FORM MAILING ADDRESS Conference secretariat: GRUPO 7 VIAJES Att.: Loreto Prado C/ Pinar nº 6 bis 2º g 28006 Madrid (España) tef.: 34-91-564.1626 Fax: 34-91-561.1721 E mail: g7pinar@grupo7viajes.com

registration form IX TTD International Symposium MAIL US GRUPO 7 VIAJES Att.: Loreto Prado C/ Pinar nº 6 bis 2º g 28006 Madrid (España) Address Information Name:... Surname:... Company:... Mailing address:... Zip Code:...City:... Telephone:...Fax:... E mail:... Accommodation Details FAX US 34-91-5611721 E-mail g7pinar@grupo7viajes.com Hotel:... Arrival date:...departure date:... Type of room: double room double room for single use

Payment REGISTRATION FEE:...Ptas. Accompanying person:...ptas. Accommodation:...Ptas. TOTAL AMOUNT TO BE PAID:...Ptas. Form of payment By check payable to: GRUPO ESPAÑOL PARA EL TRATAMIENTO DE TUMORES DIGESTIVOS Bank Transfer to: GRUPO ESPAÑOL PARA EL TRATAMIENTO DE TUMORES DIGESTIVOS. Caja Madrid Sucursal Hospital Universitario Clinico San Carlos. Account nº: 2038 1594 09 6000011368. By Credit Card (VISA, AMEX) Number:...Expiry date:... Card holder name:... Signature Note: Registration will be processed only if payment is included.

Organized by Grupo Español para el Tratamiento de Tumores Digestivos Under the auspices of Under the auspices of Under the auspices of Spanish Association for Cancer Research SOCIEDAD ESPAÑOLA DE ONCOLOGIA MEDICA