surface Peritoneal Malignancy WORKSHOP ON 19-21 athens Cytoreductive Surgery and HIPEC www.hipec2015.gr FINAL PROGRAM

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Organized by the Educational Committee of the HELLENIC SURGICAL SOCIETY WORKSHOP ON Peritoneal surface Malignancy Cytoreductive Surgery and HIPEC divani caravel Metropolitan Hospital Αmphitheater athens Endorsed by: In collaboration with the Under the auspices of the Hellenic Society of Medical Oncology 19-21 February 2015 www.hipec2015.gr FINAL PROGRAM

3 Invitation Dear colleagues, Cytoreductive surgery and perioperative intraperitoneal chemotherapy have been endorsed with remarkable zeal by surgeons and oncologists around the world. The existing medical literature provides enough Level I and II data to encourage doctors who believe in the concept of cytoreduction to expand current indications in more cases of peritoneal surface malignancy. National governing bodies on healthcare have approved cytoreductive surgery as the most effective way of treating advanced cancers with peritoneal spread. Guideline issuing international organizations are considering cytoreduction and HIPEC as an option and possibly a standard of care for certain diagnoses. It is now critical for the professionals working on peritoneal surface malignancy, to further standardize the surgical techniques, to strictly adhere to current indications for use and to provide high quality healthcare to patients. The way forward is through standardized and demanding education and training. We invite you to the Workshop on Peritoneal Surface Malignancy that will take place in Athens on 19-21 February 2015. Our aim is to bring together healthcare professionals in the field of peritoneal surface malignancy and study how to improve our practices. Our ambition is to inspire colleagues who wish to start a program and need support and further training. The Educational Committee of the Hellenic Surgical Society and the doctors of the Peritoneal Surface Malignancy Program of the Metropolitan Hospital, warmly invite you to three days of exchanging experiences and building knowledge. On behalf of the Organizing Committee, A.A. Tentes P.H. Sugarbaker CO-ORDINATORS A.A. Tentes - P.H. Sugarbaker ORGANIZING COMMITTEE A. Kambaroudis N. Pallas Th. Panoskaltsis I. Paraskevopoulos Z. Plaitakis N. Sikalias K.M. Stamou SCIENTIFIC COMMITTEE D. Bafaloukos V. Barbounis C. Christodoulou P. Prassopoulos A. Rassidakis P. Skandalakis D. Skarlos D. Voros G. Zografos INTERNATIONAL FACULTY Ch. Fotopoulou Consultant Cynecological Oncologist, Imperial College London, Queen Charlottes Hospital, London, UK O. Glehen Professor of Surgery, Centre Hospitalier Universitaire de Lyon, Lyon, France D.M. Kecmanovic Professor of Surgery, Department for Colorectal Surgery, First Surgical University Hospital, Belgrade, Serbia P. Piso Professor of Surgery, Department for Surgery, University of Regensburg, Germany P.H. Sugarbaker Director, Peritoneal Surface Malignancy Program, Washington Hospital Center, Washington DC, USA

4 Aravantinos G. Athanasiadis I. Barbounis V. Boukovinas I. Christodoulou C. Courcoutsakis N. De Bree E. Dimopoulos A. Dimosthenous K. Douzinas M. Evodia E. Galani H. Georgiadis G. Gkiokas G. Kambaroudis A. Karaitianos I. Kolovos J. Konstandoulakis M.M. Leandros E. Liakakos Th. Linardou H. Pallas N. Panopoulos C. Panoskaltsis Th. Papadimitriou Ch. Papathanasiou N. Paraskevopoulos I. Pavlaki A. Prasopoulos P. Prigouris S. Rassidakis A. Rodolakis A. Rologis D. Sagris K. Samanta E. Skarlos D. Skandalakis P. Spiliotis J. Stamou K.M. Tentes A.A. Theodorou D. Toutouzas K. Tzaninis D. Vlachos G. Voros D. Zografos G. National Faculty Director, 2 nd Department of Medical Oncology, Agioi Anargyroi Cancer Hospital, Athens Director, Department of Medical Oncology, Mitera General Hospital, Athens Director, 3 rd Department of Medical Oncology, Metropolitan Hospital, Athens Director, Department of Medical Oncology, Viocliniki, Thessaloniki Director, 2 nd Department of Medical Oncology, Metropolitan Hospital, Athens Assistant Professor of Radiology, Democritus University of Thrace, Alexandroupoli Associate Professor of Surgery, University of Crete, Herakleio Director, Department of Radiotherapy, Metropolitan Hospital, Athens, Greece Pathologist, Metropolitan Hospital, Athens, Greece Director, Department of Thoracic Surgery, Metropolitan Hospital, Athens, Greece Anaesthesiologist, Athens Medical Center Medical Oncologist, 2 nd Department of Medical Oncology, Metropolitan Hospital, Athens Director, Intencive Care Unit, Metropolitan Hospital, Athens Assistant Professor of Intensive Care Surgery, National and Kapodistrian University of Athens Associate Professor of Surgery, 5 th Department of Surgery, Aristoteleian University of Thessaloniki, Thessaloniki Director, Department of Surgical Oncology, Agios Savvas Cancer Hospital, Athens Director, Department of Radiology, Metropolitan Hospital, Athens Professor of Surgery, 1 st Department of Propaedeutic Surgery, National and Kapodistrian University of Athens Professor of Surgery, 1 st Department of Propaedeutic Surgery, National and Kapodistrian University of Athens Professor of Surgery, 1 st Department of Surgery, National and Kapodistrian University of Athens Medical Oncologist, 1 st Department of Medical Oncology, Metropolitan Hospital, Athens General Surgeon, Peritoneal Surface Malignancy Program, Metropolitan Hospital, Athens Director, Department of Medical Oncology, Agios Savvas Cancer Hospital, Athens Assistant Professor of Gynecology, National and Kapodistrian University of Athens Associate Professor of Oncology, National and Kapodistrian University of Athens Director, Department of Nuclear Medicine, Metropolitan Hospital, Athens Director, Department of Surgery, KAT Hospital, President of the Educational Committee of the Hellenic Surgical Society, Athens Professor of Pathologic Anatomy, Department of Pathologic Anatomy, National and Kapodistrian University of Athens, Athens, Greece Professor of Radiology, Democritus University of Thrace, Alexandroupoli Director, Department of Surgery, Metropolitan Hospital, Athens Professor of Pneumonology, Metropolitan Hospital, Athens Associate Professor of Surgery, 1 st Department of Obstetrics and Gynecology, National and Kapodistrian University of Athens Director, Department of Neurosurgery, Metropolitan Hospital, Athens Intensivist, Metropolitan Hospital, Athens Anaesthesiologist, Metropolitan Hospital, Athens Director, Medical Oncology Unit, Metropolitan Hospital, Athens Professor of Anatomy, President of the Central Scientific Committee, Greek National Health System Director, 1 st Department of Surgery, Metaxa Cancer Institute, Athens Colorectal Surgeon, Peritoneal Surface Malignancy Program, Metropolitan Hospital, Athens Director, Peritoneal Surface Malignancy Program, Metropolitan Hospital, Athens Associate Professor of Surgery, 1 st Department of Propaedeutic Surgery, National and Kapodistrian University of Athens Associate Professor of Surgery, 1 st Department of Propaedeutic Surgery, National and Kapodistrian University of Athens Director, Department of Medical Oncology, Athens Medical Center Associate Professor of Gynecology, 1 st Department of Obstetrics and Gynecology, National and Kapodistrian University of Athens Professor of Surgery, National and Kapodistrian University of Athens Vice Rector, Professor of Surgery, 1 st Department of Propaedeutic Surgery, National and Kapodistrian University of Athens

5 program at a glance Thursday 19 th February 2015 09.00 09.30 Registration 09.30 09.45 Welcome Addresses 09.45 11.30 ROUND TABLE 1 Diagnostic tools in peritoneal malignancy 11.30 12.00 Coffee Break 12.00 13.00 ROUND TABLE 2 Preoperative, intraoperative and postoperative care of the patients undergoing cytoreductive surgery and HIPEC 13.00 14.30 ROUND TABLE 3 Ovarian cancer 14.30 15.30 Lunch Break 15.30 16.30 ROUND TABLE 4 Gastric cancer 16.30 17.30 ROUND TABLE 5 Peritoneal sarcomatosis 17.30 18.00 Coffee Break 18.00 19.00 ROUND TABLE 6 Pseudomyxoma peritonei 19.00 19.30 OPENING CEREMONY Welcome Addresses 19.30 20.00 OPENING LECTURE 20.00 Welcome Reception divani CARAVEL HOTEL Friday 20 th February 2015 08.00 08.30 Registration Live Presentation - Educational videos METROPOLITAN AMPHITHEATER Saturday 21 st February 2015 09.00 10.00 ROUND TABLE 7 Peritoneal mesothelioma 10.00 10.45 ROUND TABLE 8 Colorectal cancer with peritoneal carcinomatosis 10.45 11.15 Coffee Break 11.45 12.15 DEBATE 1 11.45 12.15 DEBATE 2 12.15 Closing Remarks divani CARAVEL HOTEL

7 09.00 09.30 Registration Scientific Program Divani Caravel Hotel Thursday 19 th February 2015 Horizon Hall 09.30 09.45 Welcome Addresses A. Rassidakis (Chairman-Scientific Society, Metropolitan Hospital) 09.45 11.30 ROUND TABLE 1 diagnostic tools in peritoneal malignancy Chairs: J. Spiliotis, J. Kolovos The role of CT and MRI in the preoperative assessment of the extent and distribution of peritoneal carcinomatosis P. Prasopoulos The role of CT-enteroclysis in the preoperative assessment of the extent and distribution of peritoneal carcinomatosis N. Courcoutsakis The role of PET-CT in the preoperative diagnosis of peritoneal malignancy N. Papathanasiou The role of diagnostic laparoscopy in the preoperative assessment of peritoneal malignancy K. Stamou Discussion 11.30 12.00 Coffee Break 12.00 13.00 round TABLE 2 Preoperative, intraoperative and postoperative care of the patients undergoing cytoreductive surgery and HIPEC Chairs: G. Georgiadis, G. Gkiokas Preoperative assessment and preparation of the patient awaiting cytoreduction and HIPEC E. Evodia Intraoperative monitoring and haemodynamic management of the patient undergoing cytoreduction and HIPEC E. Samanta Monitoring of patients undergoing cytoreductive surgery and HIPEC in the ICU K. Sagris

8 Scientific Program Divani Caravel Hotel Thursday 19 th February 2015 Horizon Hall 13.00 14.30 round TABLE 3 Ovarian cancer Chairs: A. Rodolakis, G. Vlachos Surgical staging of early ovarian cancer. Th. Panoskaltsis Peri-operative chemotherapy in early ovarian cancer. G. Aravantinos Cytoreductive surgery in locally advanced ovarian cancer, results. The gynecological view. Ch. Fotopoulou Cytoreductive surgery and perioperative intraperitoneal chemotherapy in locally advanced ovarian cancer, results. The surgical view. D. Kesmanovic Neo-adjuvant and adjuvant chemotherapy in locally advanced ovarian cancer. Ch. Papadimitriou Discussion 14.30 15.30 lunch Break 15.30 16.30 round TABLE 4 gastric cancer Chairs: Th. Liakakos, E. Galani Cytoreductive surgery and HIPEC in gastric cancer with peritoneal carcinomatosis, results. P. Piso Neo-adjuvant and adjuvant chemotherapy in gastric cancer with peritoneal chemotherapy. V. Barbounis Radical gastric resection in locally advanced gastric cancer D. Theodorou The role of radiotherapy in locally advanced gastric cancer. A. Dimopoulos Discussion 16.30 17.30 round TABLE 5 Peritoneal sarcomatosis Chairs: E. Leandros, A. Kambaroudis Cytoreductive surgery and HIPEC in peritoneal sarcomatosis, results. P. Piso Neo-adjuvant and adjuvant chemotherapy in peritoneal sarcomatosis. D. Tzaninis Discussion 17.30 18.00 Coffee Break

9 Scientific Program Divani Caravel Hotel Thursday 19 th February 2015 Horizon Hall 18.00 19.00 round TABLE 6 Pseudomyxoma peritonei Chairs: G. Zografos, K. Toutouzas Histopathology of pseudomyxoma peritonei. K. Pavlaki Cytoreductive surgery and perioperative intraperitoneal chemotherapy in pseudomyxoma peritonei, results. J. Spiliotis Neo-adjuvant and adjuvant chemotherapy in pseudomyxoma peritonei. Ι. Athanasiadis Discussion 19.00 19.30 OPENING CEREMONY Welcome Addresses I. Paraskevopoulos Chairman of the Educational Committee, Hellenic Surgical Society P. Skandalakis President of the Central Scientific Committee, Greek National Health System G. Zografos Vice-Rector of the National Kapodistrian University of Athens G. Aravantinos On behalf of the Hellenic Society of Clinical Oncologists Α. Rologis Administration Metropolitan Hospital 19.30 20.00 OPENING LECTURE Chair: A.A. Tentes, A. Rassidakis When and how to use HIPEC P. H. Sugarbaker 20.00 Welcome Reception METROPOLITAN HOSPITAL AMPHITHEATER Friday 20 th February 2015 08.00 08.30 Registration - Coffee Live Presentation - Educational videos

10 Scientific Program Divani Caravel Hotel Saturday 21 st February 2015 Horizon Hall 09.00-10.00 round TABLE 7 Peritoneal mesothelioma Chairs: A. Douzinas, E. De Bree Histopathology of peritoneal mesothelioma. K. Dimosthenous Malignant Peritoneal Mesothelioma: Doe s Comprehensive Treatment Should Include Perioperative Chemotherapy? Multi-Institutional Experience O. Glehen Neo-adjuvant and adjuvant chemotherapy in peritoneal mesothelioma. I. Boukovinas Discussion 10.00-10.45 round TABLE 8 Colorectal cancer with peritoneal carcinomatosis Chairs: S. Prigouris, P. Panopoulos Cytoreductive surgery and HIPEC in colorectal and appendiceal cancer with peritoneal carcinomatosis, results. O. Glehen Neo-adjuvant and adjuvant chemotherapy in colorectal and appendiceal cancer with peritoneal carcinomatosis. H. Linardou Discussion 10.45 11.15 Coffee Break 11.15-11.45 debate 1 Moderators: D. Voros, M. Konstandoulakis Cancer of the pancreas: resection+hipec P. H. Sugarbaker Cancer of the pancreas. Resection+systemic chemotherapy C. Christodoulou 11.45-12.15 debate 2 Moderators: I. Karaitianos, N. Pallas Locally advanced colo-rectal cancer: resection+hipec A. A. Tentes Locally advanced colo-rectal cancer. Neo-adjuvant chemotherapy+resection+systemic chemotherapy C. Christodoulou 12.15 Closing Remarks P. H. Sugarbaker, A. A. Tentes

11 General Information DATES AND VENUES The Scientific Program of the Workshop will be held on February 19 th and 21 st, 2015, at the Horizon Meeting Hall-Divani Caravel Hotel (address: Vasileos Alexandrou Av. 2 161 21 Athens-Greece, tel.: 21 0720 7000), & The Live Presentation on February 20 th will take place at the Metropolitan Hospital Amphitheater (address: Ethnarchou Makariou 9 & El. Venizelou 1,18547 N. Faliro - Athens Greece, tel.: 210 48 09 000) LANGUAGE The official language of the Workshop will be English. PC RECEPTION DESK A PC reception desk for acceptance and checking of USBs will be located at the Divani Caravel. Speakers are kindly requested to hand their presentations at least half an hour prior to their scheduled time. CERTIFICATE OF ATTENDANCE All participants will receive a certificate of attendance after the end of the scientific sessions. Separate certificates will be handed to those who will participate at the Live and Educational videos session. REGISTRATION FEES REGISTRATION FEES Until January 20 th After January 20 th General participation 19 & 21/02/2015 50 60 At the Scientific Sessions Divani Caravel Hotel *Live Presentation 20/02/2015 50 60 Live & Educational videos Session Metropolitan Hospital General participation fees include: Admission to the scientific Sessions on the 19 th & 21 st of February at the Divani Caravel hotel Workshop material Coffee and light lunch breaks Certificate of attendance Live Presentation fees include: Admission to the Live and Educational videos session on the 20 th of February at the Metropolitan Hospital Amphitheater Coffee break Certificate of attendance * Registration at the Scientific Sessions at the Divani Caravel, is obligatory, in order to participate at the Live Presentation. Limited positions are available (up to 50). The participations will be handled on first come-first serve basis. 23 % VAT will be added to registration fees for issuance of invoices. ACCOMMODATION Room rates include breakfast and taxes HOTEL ACCOMMODATION SINGLE DOUBLE Divani Caravel 140 140 CANCELLATION POLICY FOR REGISTRATION Cancellation requests must be made to the Congress Secretariat in writing. For cancellation received by January 31 st, 2015, a refund of the total fee, less 25 % as administration charge, will be made. After that date refunds will not be possible. Payment conditions for Hotel accommodation One (1) night deposit, payable to ERA Ltd, is required in order to confirm your Hotel reservation. Full prepayment for Hotel reservation, should reach ERA Ltd not later than February 8th, 2015 CANCELLATION POLICY FOR HOTEL RESERVATION All changes or cancellations have to be made in writing to ERA Ltd (and not the Hotel) - Written cancellation received by January 31 st, no cancellation fees apply. - Written cancellation received from January 31 st, and onwards: Full cancellation fees. - In the event of non-show, the hotel will automatically release the reservation and payment will be non-refundable. METHOD OF PAYMENT FOR REGISTRATION/ HOTEL ACCOMMODATION Payment can be effected either: a) By bank remittance stating the Workshop on peritoneal malignancy surface, as well as the name of the participant: To ALPHA BANK, Account number: 101-00-2002-044307, IBAN Code GR66 0140 1010 1010 0200 2044 307 (Swift code: CRBAGRAAXXX), Holders account: ERA LTD, Bank address: 40 STADIOU STR. P.C.102-52, ATHENS Please enclose a copy of transfer receipt with the form. Charges to be paid by sender. The copy of the transfer receipt should be sent to ERA LTD within 7 days by fax to: +30 210 3631690 or by e-mail to info@era.gr in order to guarrantee your reservation. Otherwise, your reservation will not be valid. Charges are the responsibility of the participants and should be paid at source in addition to the accommodation fees. b) By major credit cards. Please complete the relevant information as described in the enclosed registration form. OFFICIAL Workshop Secretariat &Travel Agency ERA Ltd CONGRESSES EVENTS BUSINESS TRAVEL INCENTIVES TOURISM 17, Asklipiou Str., 10680 Athens-Greece Tel.: +30 210 3634944, Fax: +30 210 3631690, E-mail: info@era.gr, Web site: www.era.gr

Organized by the Educational Committee of the Hellenic SURGICAL SOCIETY Peritoneal ONsurface Malignancy WORKSHOP 19 21 February, 2015 Divani Caravel Hotel /Metropolitan Hospital R E G I S T R A T I O N & R E S E R V A T I O N F O R M Please type or print in block letters and return this form to the official Workshop Secretariat: ERA Ltd 17, Asklipiou Str- 106 80, Athens, Greece, either by e-mail: info@era.gr or by Fax: (+30) 210 3631 690. LAST NAME:... FIRST NAME:... TITLE:... Mr. Mrs. Ms. Dr. Prof. INSTITUTE:... ADDRESS:... NO.:... POSTAL CODE:... CITY :... TEL: :... E-MAIL:... I. REGISTRATION FEES REGISTRATION FEES Until January 20 th After January 20 th General participation 19 & 21/02/2015 At the Scientific Sessions Divani Caravel Hotel 50 60 *Live Presentation 20/02/2015 Live & Educational videos Session Metropolitan Hospital 50 60 TOTAL General participation fees include: Admission to the scientific Sessions on the 19 th & 21 st of February at the Divani Caravel hotel Workshop material Coffee and light lunch breaks Certificate of attendance Live Presentation fees include: Admission to the Live and Educational videos session on the 20 th of February at the Metropolitan Hospital Amphitheater Coffee break Certificate of attendance * Registration at the Scientific Sessions at the Divani Caravel, is obligatory, in order to participate at the Live Presentation. Limited positions are available (up to 50). The participations will be handled on first come-first serve basis. 23 % VAT will be added to registration fees for issuance of invoices. II. HOTEL ACCOMMODATION Room rates include breakfast and taxes HOTEL ACCOMMODATION SINGLE DOUBLE X nights Divani Caravel 140 140 TOTAL GRAND TOTAL

CANCELLATION POLICY FOR REGISTRATION Cancellation requests must be made to the Congress Secretariat in writing. For cancellation received by January 31 st, 2015, no cancellation fees apply. After that date refunds will not be possible. Payment conditions for Hotel accommodation One (1) night deposit, payable to ERA Ltd, is required in order to confirm your Hotel reservation. Full prepayment for Hotel reservation, should reach ERA Ltd not later than February 8 th, 2015. CANCELLATION POLICY FOR HOTEL RESERVATION All changes or cancellations have to be made in writing to ERA Ltd (and not the Hotel) - Written cancellation received by January 31 st, 2015, no cancellation fees apply. - Written cancellation received from January 31 st, 2015 and onwards: Full cancellation fees. - In the event of non-show, the hotel will automatically release the reservation and payment will be non-refundable. METHOD OF PAYMENT FOR REGISTRATION/ HOTEL ACCOMMODATION Payment can be effected either: a) By bank remittance stating the Workshop on peritoneal malignancy surface, as well as the name of the participant: To ALPHA BANK, Account number: 101-00-2002-044307, IBAN Code GR66 0140 1010 1010 0200 2044 307 (Swift code: CRBAGRAAXXX), Holders account: ERA LTD, Bank address: 40 STADIOU STR. P.C.102-52, ATHENS Please enclose a copy of transfer receipt with the form. Charges to be paid by sender. The copy of the transfer receipt should be sent to ERA LTD within 7 days by fax to: +30 210 3631690 or by e-mail to info@era.gr in order to guarantee your reservation. Otherwise, your reservation will not be valid. Charges are the responsibility of the participants and should be paid at source in addition to the accommodation fees. b) By major credit cards. Please complete the relevant information as described in the enclosed registration form. A written confirmation will be sent to you by ERA Ltd upon receiving your Registration & Reservation form and respective fees. For deposit: I authorize ERA Ltd to debit my Credit Card, for the Sum of: EUR... For full payment: I authorize ERA Ltd to debit my Credit Card by February 8th and settle my debit account to the Congress. VISA MASTERCARD AMERICAN EXPRESS Card Number: / / / 3 last digits: valid from (For AMEXCO card holders)... /... Expiration Date:.../... Signature... D date.../.../ 2015

15 acknowledgements The Organizing Committee gratefully acknowledges the contribution of the following companies in the support of the Workshop

Η ΑΝΑΣΤΑΣΙΟΣ ΜΑΥΡΟΓΕΝΗΣ Α.Ε. δραστηριοποιείται στον χώρο της Υγείας τα τελευταία 25 χρόνια και αντιπροσωπεύει έξι διεθνείς καταξιωμένους οίκους ιατροτεχνολογικών προϊόντων, έχοντας δυναμική πορεία ανάπτυξης. Νοιώθουμε μεγάλη ηθική ευθύνη να βρισκόμαστε πάντα κοντά στους λειτουργούς υγείας και τους πελάτες μας, να κατανοούμε τις ανάγκες τους, να διαθέτουμε καινοτόμα προϊόντα υψηλής ποιότητας και να αναπτύσσουμε υπηρεσίες υποστήριξης που να βελτιώνουν την ποιότητα ζωής των χρηστών των προϊόντων μας. Ένα βήμα προς τα εμπρός, ένα βήμα πιο κοντά σας! Αναστάσιος Μαυρογένης Α.Ε. Κεντρικά: Γκιώνας 1Α, Τ.Κ. 144 51, Μεταμόρφωση, Τ: 210 20 20 232, Φ: 210 20 20 775