FEDERICA ROMANI CURRICULUM VITAE AND PUBLICATIONS Date and place of birth 2 th December 1980, Rome Residence Via V. Tangorra, 9ca 00191 Roma, ITALY tel: +39 3496903379 e-mail: f.romani@yahoo.it Education June 1999: High School state degree (100/100) June 1999: First Certificate in English of Cambridge University (grade C). 2004-2005: Internship as pre-laurea training in the Institute of Obstetric and Gynecological Clinics, at the Catholic University of Rome. July 2005: Italian "Laurea cum laude" as Doctor in Medicine at the Catholic University of Rome. 2007- : Residency at the same university attending the specialization training course and activity in Gynecology Post-lauream courses Training Course in "Gynecological and Obstetric Ecography" Training Course in "Hormonal Therapies in Gynecology and Obstetrics" Research activity Since 2005 her scientific activity has been focused on the study of the physiology and physiopathology of the ovaric, endometric and pheto-placental unit functions. Using primary cells culture of corpus luteum, endometrium, trophoblast and human umbelical vein endothelial cells (HUVEC) FR acquired experience in basic biology and in techniques such as ELISA, RIA and PCR. This activity has been described in several publications in peer reviewed journals (see the list below). FR has gained experience in the preparation of seminal fluids for first level ARTs. FR also won an award by the Society of Gynecological Investigation (SGI) in 2009. Publications in peer reviewed journals: 1. Regulation of VEGF synthesis and release by human luteal cells in vitro. Tropea A, Miceli F, Minici F, Tiberi F, Orlando MT, Gangale MF, Romani F, Catino S, Mancuso S, Navarra P, Lanzone A, Apa R. J Clin Endocrinol Metab. 2006 Jun;91(6):2303-9.
2. Ghrelin in vitro modulates cell proliferation and vasoactive factors synthesis in Human Umbilical Vein Endothelial Cells. Minici F, Miceli F, Tiberi F, Tropea A, Orlando M, Gangale MF, Romani F, Catino S, Lanzone A, Apa R. Fertil Steril. 2007, 88(4 Suppl):1158-66. 3. Ghrelin affects the release of luteolytic and luteotropic factors in human luteal cells. Tropea A, Tiberi F, Minici F, Orlando M, Gangale MF, Romani F, Miceli F, Catino S, Mancuso S, Sanguinetti M, Lanzone A, Apa R. J Clin Endocrinol Metab. 2007; 92(8):3239-45. 4. Paracrine regulation of endometriotic tissue. Minici F, Tiberi F, Tropea A, Fiorella M, Orlando M, Gangale MF, Romani F, Catino S, Campo S, Lanzone A, Apa R. Gynecol Endocrinol. 2007; 23(10):574-80. 5. Endometriosis and human infertility: a new investigation into the role of eutopic endometrium. Minici F, Tiberi F, Tropea A, Orlando M, Gangale MF, Romani F, Campo S, Bompiani A, Lanzone A, Apa R. Hum Reprod. 2008; 23(3):530-37 6. Prokineticin 1 mrna expression in the endometrium of healthy women and in the eutopicendometrium of women with endometriosis. Tiberi F, Tropea A, Apa R, Romani F, Lanzone A, Marana R. Fertil Steril. Fertil Steril. 2010 May 1;93(7):2145-9. Epub 2009 Mar 14. 7. Estrogens and androgens affect human luteal cell function. Tropea A, Lanzone A, Tiberi F, Romani F, Catino S, Apa R. Fertil Steril. 2010 Nov;94(6):2257-63. Epub 2010 Mar 21. 8. Prokineticin 1, homeobox A10, and progesterone receptor messenger ribonucleic acid expression in primary cultures of endometrial stromal cells isolated from endometrium of healthy women and from eutopic endometrium of women with endometriosis. Tiberi F, Tropea A, Romani F, Apa R, Marana R, Lanzone A. Fertil Steril. 2010 Dec;94(7):2558-63. Epub 2010 Apr 18. 9. Nicotine and cotinine affect the release of vasoactive factors by trophoblast cells and human umbilical vein endothelial cells. Romani F, Lanzone A, Tropea A, Tiberi F, Catino S, Apa R. Placenta. 2010 Dec 8. [Epub ahead of print] Participation to National and International Conferences: Organization for Human Brain Mapping Conference. Brighton UK, June 10-14, 2001. Organization for Human Brain Mapping Conference. New York, June 19-22, 2003. Neoplasie del Colon-Retto: dalla prevenzione alla terapia. Roma, 14 Novembre 2003. Giornata di Chirurgia Epato-biliare in onore di Henri Bismuth. Roma, 24 Aprile 2004 1st International Summit Meeting of the Society for Gynecologic Investigation. Siena, November 10-12, 2005 L amenorrea VIII Week-end clinico Società Italiana della Riproduzione. Roma, 25-26 Novembre 2005. IV Seminario Nazionale Dottorati di Ricerca in Ginecologia e Ostetricia. Siena, 3 Febbraio 2006. Corso di formazione e di competenza in Ecografia Ginecologica ed Ostetrica. SEOG. Roma, 6-8 Marzo 2006 12th World Congress of Gynecological Endocrinology. Florence, March 2-5, 2006.
82 Congresso Nazionale SIGO. 47 Congresso AOGOI. 14 Congresso AGUI: Roma 1-4 ottobre 2006. Terapie ormonali in ginecologia ed ostetricia. Università degli studi di Siena, Dipartimento di Pediatria, Ostetricia e Medicina della Riproduzione. Siena 15-18 Ottobre 2006. Aggiornamenti in Ostetricia e Ginecologia. Congresso Straordinario-Associazione Ginecologi Universitari Italiani (AGUI), Roma, 18-19 Maggio 2007. L endometriosi, il punto su diagnosi e trattamenti 3th International Congress on Endometriosis. Roma, 25-26 Maggio 2007. 2nd SGI International Summit on Reproductive Medicine, Valencia (Spagna), 8-10 Novembre 2007. 13th World Congress of Gynecological Endocrinology, Firenze (Italia), 28 Febbraio - 2 Marzo 2008. I Congresso Nazionale della Federazione Italiana di Ostetricia e Ginecologia (FIOG), Roma 5-7 Novembre 2008. Interventional Radiology in Obstetrics & Gynecology. Policlinico A.Gemelli Roma, 11-12 Febbraio 2009. 56th Annual Meeting of Society of Gynecological Investigation (SGI), Glasgow (Scozia), 17-21 Marzo 2009. 1st Consensus Conference on Deep Endometriosis. Policlinico A.Gemelli Roma, 22-24 Aprile 2009. 4nd International Congress on Endometriosis, 28-30 Maggio 2009, Università Cattolica del Sacro Cuore, Roma. 57th Annual Meeting of Society of Gynecological Investigation (SGI), Orlando (Florida), 17-21 Marzo 2010. Oral presentations: Ghrelin desacilato ed obestatina: effetti in vitro dei peptidi ghrelin-correlati su cellule di corpo luteo umano. I Congresso Unificato delle Società Italiane di Medicina della Riproduzione - Riccione, 28-30 maggio 2009. The in vitro effect of Proghrelin-derived peptides on purified human luteal cells. 2nd Symposium Partisco- Romanum. The Hungarian Academy of Rome. March 5-7, 2009. Abstracts and Posters: 1. IGFs AFFECT VEGF SYNTHESIS IN HUMAN LUTEAL CELLS. Tropea A, Miceli F, Minici F, Tiberi F, catino S, Orlando MT, Gangale MF, Romani F, Lanzone A, Apa R. Human Reproduction Vol 16,Abstract Books: Abs P476. 21th Annual Meeting of the European Society of Human Reproduction and Embriology (ESHRE), Copenhagen (Denmark) June 19-22, 2005. 2. IN HUMAN TROPHOBLAST CELLS THE EXPRESSION OF VEGF IS DECREASED BY CRF AND ETs. Tropea A, Minici F, Miceli F, Orlando MT, Gangale MF, Tiberi F, Romani F, Lanzone A, Apa R. Poster presentation. (n 43) I SGI International Meeting Preterm Birth, Siena (Italy) November 10-12, 2005. 3. GHRELIN AFFECTS ON HUVEC: A POSSIBLE ROLE ON FETO-PLACENTAL UNIT. Tropea A, Minici F, Miceli F, Orlando MT, Gangale MF, Tiberi F, Romani F, Lanzone A, Apa
R. Poster presentation. (n 28) I SGI International Meeting Preterm Birth, Siena (Italy) November 10-12, 2005. 4. ANDROGENS DECREASE VEGF EXPRESSION AND SECRETION IN HUMAN LUTEAL CELLS. Tropea A, Minici F, Miceli F, Orlando MT, Gangale MF, Tiberi F, Romani F, Lanzone A, Apa R. 13th World Congress on Human Reproduction, Florence (Italy) March 2-5, 2006. 5. POSSIBLE ROLE OF GHRELIN IN THE REGULATION OF HUMAN LUTEAL FUNCTION IN VITRO. Apa R, Tropea A, Minici F, Miceli F, Orlando MT, Gangale MF, Tiberi F, Romani F, Lanzone A. 13th World Congress on Human Reproduction, Florence (Italy) March 2-5, 2006. 6. ENDOMETRIOSIS AND HUMAN INFERTILITY : A NEW INVESTIGATION ON THE ROLE OF EUTPOIC ENDOMETRIUM. Apa R, Minici F, Miceli F, Tiberi F, Tropea A, Orlando MT, Gangale MF, Romani F, Bompiani A, Lanzone A. Abs 634. 53th Annual Meeting of the Society of Gynecological Investigation (SGI) Toronto (Canada) March 22-25, 2006. 7. GHRELIN AFFECTS P AND VEGF PRODUCTION BY HUMAN LUTEAL CELLS. Apa R, Minici F, Miceli F, Tiberi F, Tropea A, Orlando MT, Gangale MF, Romani F, Bompiani A, Lanzone A. Abs 583. 53th Annual Meeting of the Society of Gynecological Investigation (SGI) Toronto (Canada) March 22-25, 2006. 8. COULD ANDROGENS INFLUENCE HUMAN LUTEAL CELLS FUNCTION? Apa R, Tropea A, Miceli F, Minici F, Orlando M, Gangale MF, Romani F, Tiberi F, Catino S, Nestorini R, Lanzone A. Abs 486. 54th Annual Meeting of the Society of Gynecological Investigation (SGI) Reno (Nevada) March 14-17, 2007. 9. NICOTINE AND COTININE DECREASE SOLUBLE FMS-LIKE TYROSINE KINASE (Sflt1) AND SOLUBLE ENDOGLIN (seng) SECRETION BY HUMAN TROPHOBLAST CELLS. Tropea A, Miceli F, Minici F, Orlando M, Gangale MF, Romani F, Tiberi F, Catino S, Nestorini R, Lanzone A, Apa R. Abs 747. 54th Annual Meeting of the Society of Gynecological Investigation (SGI) Reno (Nevada) March 14-17, 2007. 10. ENDOCRINE GLAND-DERIVED VASCULAR ENDOTHELIAL GROWTH FACTOR MRNA EXPRESSION IN EUTOPIC ENDOMETRIAL SAMPLES FROM WOMEN AFFECTED BY ENDOMETRIOSIS. Tiberi F, Tropea A, Orlando M, Gangale M F, Romani F, Catino S, Marana R, Lanzone A, Apa R. 2nd SGI International Summit on Reproductive Medicine, Valencia (Spagna), November 8-10, 2007. 11. NICOTINE AND COTININE AFFECT THE PRODUCTION OF SOLUBLE FMS-LIKE TYROSINE KINASE (SFLT1), SOLUBLE ENDOGLIN (SENG) AND THEIR LIGANDS BY HUMAN TROPHOBLAST CELLS. Tropea A, Orlando MT, Gangale MF, Romani F, Tiberi F, Loiudice I, Catino S, Merola A, Lanzone A, Apa R. 13th World Congress of Gynecological Endocrinology, Firenze (Italia), February 28 - March 2, 2008. 12. COULD ANDROGENS INFLUENCE HUMAN LUTEAL CELLS FUNCTION? Tropea A, Orlando MT, Gangale MF, Romani F, Loiudice I, Tiberi F, Catino S, Lanzone A, Apa R. 55th Annual Meeting of Society of Gynecological Investigation (SGI), San Diego (California), March 26-29, 2008. 13. THE IN VITRO EFFECT OF PROGHRELIN-DERIVED PEPTIDES ON PURIFIED HUMAN LUTEAL CELLS. AFFECT VEGF SYNTHESIS IN HUMAN LUTEAL CELLS.
Tropea A, Orlando MT, Gangale MF, Romani F, Loiudice I, Tiberi F, Catino S, Lanzone A, Apa R. 55th Annual Meeting of Society of Gynecological Investigation (SGI), San Diego (California), March 26-29, 2008. 14. IN VITRO EFFECT OF HYPOXIA ON HUMAN TROPHOBLAST CELLS AND HUVEC. Tropea A, Orlando MT, Romani F, Tiberi F, Loiudice I, Condoluci C, Catino S, Lanzone, Apa R. 56th Annual Meeting of Society of Gynecological Investigation (SGI), Glasgow (Scozia), March 17-21, 2009. 15. THE IN VITRO EFFECT OF PHTHALATES ON HUMAN CORPUS LUTEUM. Tropea A, Orlando MT, Romani F, Tiberi F, Condoluci C, Familiari A, Catino S, Lanzone, Apa R. 57th Annual Meeting of Society of Gynecological Investigation (SGI), Orlando (Florida), March 17-21, 2010. 16. THE IN VITRO EFFECT OF PHTHALATES ON HUMAN CORPUS LUTEUM. Tropea A, Orlando MT, Romani F, Tiberi F, Condoluci C, Familiari A, Catino S, Lanzone, Apa R. 57th Annual Meeting of Society of Gynecological Investigation (SGI), Orlando (Florida), March 17-21, 2010.