, Italy ADVANCED PROGRAM F E B R U A R Y 11-13, 2016 INTERVENTIONAL CARDIOLOGY HD LIVE CASES ADVANCED AND BASIC WORKSHOPS



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LEADERSHIP IN LIVE CASE DEMONSTRATION COURSE DIRECTORS Antonio Colombo, MD Eberhard Grube, MD Martin B. Leon, MD Carlo Di Mario, MD Jeffrey W. Moses, MD Gregg W. Stone, MD JOINT INTERVENTIONAL MEETING IN PARTNERSHIP WITH ADVANCED PROGRAM F E B R U A R Y 11-13, 2016, Italy w w w. j i m - v a s c u l a r. c o m INTERVENTIONAL CARDIOLOGY HD LIVE CASES ADVANCED AND BASIC WORKSHOPS SPECIAL BRS SESSION on Wednesday February 10

Faculty Members COURSE DIRECTORS Antonio COLOMBO, MD Eberhard GRUBE, MD Martin B. LEON, MD Carlo DI MARIO, MD Jeffrey W. MOSES, MD Gregg W. STONE, MD ASSOCIATE DIRECTORS Alexandre C. ABIZAID, MD Christoph NABER, MD Seung JUNG PARK, MD Stephan WINDECKER, MD LIVE SATELLITE TRANSMISSIONS From Milan PRESENTED BY ST. RAFFAELE HOSPITAL Milan, Italy COLUMBUS HOSPITAL HEART CENTER Milan, Italy From Bonn From New York UNIVERSITY HOSPITAL BONN Bonn, Germany COLUMBIA UNIVERSITY New York, USA Visit our website for registration on-line 2

Useful Addresses ORGANIZING SECRETARIAT Victory Project Congressi Via C. Poma, 2 20129 Milan Italy Phone +39 02 89 05 35 24 Fax +39 02 20 13 95 e-mail info@victoryproject.it CONGRESS VENUE Milan Marriott Hotel Via Washington, 66 20146 Milan Italy Phone +39 02 48 521 www.milanmarriotthotel.com Program updated to January 5 th 2016 3

Welcome! We are very pleased to welcome you in Milan on February 11-13, 2016! The partnership with TCT/CRF is an infusion of new energy to JIM to better deliver a fruitful educational experience to the attendee. JIM is The Live Case Meeting and it will keep this unique characteristic. We will demonstrate what we mean for optimal implantation of a drug eluting stent and of bioresorbable scaffold in complex coronary lesions. We believe that this strategy will further improve the safety and performance of these devices. Live demonstrations will include treatment of adult valvular heart disease, structural heart disease. We will introduce new devices without loosing close contact to the daily practice of the busy Interventionist. The meeting maintains its format with State of the Art lectures given by experts in the field. Lunch symposia fulfill this target. This year we have again live transmission on Saturday morning (including Milan) in order to maintain a well-balanced distribution of live cases throughout the entire meeting. More emphasis and expansion are given to those sessions in which attendees can present and discuss cases. The Meeting will take place in Milan at Milan Marriott Hotel. It combines a comfortable accommodation solution with a large and efficient Congress Centre. We all look forward to seeing all our friends at JIM 2016 Antonio Colombo, MD Eberhard Grube, MD 4

Faculty Members Invited Faculty Alexandre C. Abizaid, MD Sao Paulo - Brazil Eustachio Agricola, MD Milan - Italy Yaron Almagor, MD Jerusalem - Israel Dominick Angiolillo, MD Jacksonville, FL - USA David Antoniucci, MD Florence Italy Marco Barbanti, MD Catania - Italy Antonio Bartorelli, MD Milan - Italy Francesco Bedogni, MD Milan - Italy Sergio Berti, MD Massa - Italy Carlo Briguori, MD Naples - Italy Todd J. Brinton, MD Stanford, CA - USA Maurice Buchbinder, MD La Jolla, CA - USA Lutz Buellesfeld, MD Bonn Germany Davide Capodanno, MD Catania - Italy Antonio Colombo, MD Milan - Italy Sameer Dani, MD Ahmedabad - India Keith Dawkins, MD London - UK Giuseppe De Luca, MD Novara - Italy Federico De Marco, MD Milan - Italy Paolo Denti, MD Milan - Italy Carlo Di Mario, MD London - UK Dariusz Dudek, MD Krakow - Poland Ted Feldman, MD Evanston, IL - USA Andrea Gagnor, MD Rivoli, TO - Italy Alfredo R. Galassi, MD Catania - Italy Roberto Garbo, MD Turin - Italy Eulogio Garcia, MD Madrid - Spain Cosmo Godino, MD Milan - Italy Eberhard Grube, MD Bonn - Germany Giulio Guagliumi, MD Bergamo Italy 5

Faculty Members Invited Faculty Michael Haude, MD Neuss - Germany Christian Hengstenberg, MD München - Germany David Hildick-Smith, MD Brighton UK Hazem Khamis, MD 6th of October City - Egypt Susheel Kodali, MD New York, NY - USA Karl Heinz Kuck, MD Hamburg Germany Ganesh Kumar, MD Mumbai - India Azeem Latib, MD Milan - Italy Pedro Lemos, MD Sao Paulo - Brazil Martin B. Leon, MD New York, NY USA Maciej Lesiak, MD Poznan - Poland Francesco Maisano, MD Zurich - Switzerland Ganesh Manoharan, MD Belfast - UK Alfredo Marchese, MD Bari - Italy Roxana Mehran, MD New York, NY - USA Oscar Mendiz, MD Buenos Aires - Argentina Alberto Menozzi, MD Parma - Italy Ghada Mikhail, MD London - UK Neal Moat, MD London - UK Raul Moreno, MD Madrid - Spain Jeffrey W. Moses, MD New York, NY USA Giuseppe Musumeci, MD Bergamo - Italy Sunao Nakamura, MD Tokyo - Japan Peter O Kane, MD Bournemouth - UK Eustaquio Onorato, MD Bergamo - Italy Jacopo A. Oreglia, MD Milan - Italy Tullio Palmerini, MD Bologna - Italy Seung-Jung Park, MD Seoul - Korea Anna Sonia Petronio, MD Pisa - Italy Augusto Pichard, MD Washington, DC - USA Francesco Prati, MD Rome Italy Patrizia Presbitero, MD Turin - Italy Bernhard Reimers, MD Rozzano, MI Italy Marco Roffi, MD Genéve - Switzerland Martin Rothman, MD London - UK Giuseppe Massimo Sangiorgi, MD Rome - Italy Gennaro Sardella, MD Rome - Italy Bruno Scheller, MD Homburg - Germany Joachim Schofer, MD Hamburg - Germany Patrick W. Serruys, MD Rotterdam - The Netherlands Georgios Sianos, MD Thessaloniki - Greece Horst Sievert, MD Frankfurt - Germany Pieter C. Smits, MD Rotterdam - The Netherlands Mohamed Ahmed Sobhy, MD Alexandria - Egypt Giulio Stefanini, MD Rozzano, MI - Italy 6

Faculty Members Invited Faculty Gregg W. Stone, MD New York, NY - USA Corrado Tamburino, MD Catania - Italy Giuseppe Tarantini, MD Padova - Italy Fabrizio Tomai, MD Rome - Italy Hendrik Treede, MD Halle - Germany Nicolas Van Mieghem, MD Rotterdam - The Netherlands Arnoud W.J. van t Hof, MD Zwolle - The Netherlands Ferdinando Varbella, MD Rivoli, TO - Italy Francesco Versaci, MD Rome - Italy Costantin Von Zur Mühlen, MD Freiburg - Germany Marco Wainstein, MD Porto Alegre - Brazil Ron Waksman, MD Washington, DC - USA Jochen Woehrle, MD Ulm - Germany Alan Yeung, MD Stanford, CA - Usa 7

Faculty Members Columbus Hospital Heart Center, Milan Faculty and Operators Antonio Colombo, MD Bruno Damascelli, MD Leo Finci, MD Azeem Latib, MD Gloria Melzi, MD Fellow and Research Associates Richard Jabbour, MD Hiroyoshi Kawamoto, MD Akihito Tanaka, MD Cardiology and Intensive Coronary Care Sections Raffaella Alpago, MD Giancarlo Biagi, MD Alfredo Castelli, MD Federica Della Rocca, MD University Hospital, Bonn Faculty and Operators Eberhard Grube, MD Christoph Hammerstingl, MD Georg Nickenig, MD Jan Malte Sinning, MD Nikos Werner, MD Cardiovascular Surgery Department Armin Welz, MD Fritz Mellert, MD Wolfgang Schiller, MD Anaesthesiology Department Andreas Hoeft, MD Stefan Weber, MD Anaesthesiology Department Romeo Arienta, MD Stefano Fattore, MD Pierluigi Villa, MD Stefano Tredici, MD 8

Faculty Members San Raffaele Hospital, Milan Faculty and Operators Antonio Colombo, MD Lorenzo Azzalini, MD Mauro Carlino, MD Alfredo Castelli, MD Alaide Chieffo, MD Francesco Giannini, MD Azeem Latib, MD Matteo Montorfano, MD Fellows and Research Associates Marco Ancona, MD Richard Jabbour, MD Hiroyoshi Kawamoto, MD Antonio Mangieri, MD Damiano Regazzoli, MD Stefano Stella, MD Cardiothoracic Department Ottavio Alfieri, MD Section Director Andrea Blasio, MD Nicola Buzzatti, MD Alessandro Castiglioni, MD Micaela Cioni, MD Michele De Bonis, MD Paolo Denti, MD David Ferrara, MD Andrea Fumero, MD Giuseppe Iaci, MD Giovanni La Canna, MD Elisabetta La Penna, MD Stefano Moriggia, MD Simona Nascimbene, MD Alessandro Verzini, MD Cardiology and Intensive Coronary Care Sections Alberto Margonato, MD Section Director Eustachio Agricola,MD Carlo Ballarotto, MD Alberto Cappelletti, MD Andrea Conversano, MD Cosmo Godino, MD Valeria Magni, MD Michele Opizzi, MD Vascular Surgery Section Roberto Chiesa, MD Section Director Domenico Astore, MD Domenico Baccellieri,MD Luca Bertoglio, MD Renata Castellano, MD Laura Dordoni, MD Gloria Esposito, MD Germano Melissano, MD Yamume Tshomba, MD Anaesthesiology and Cardiovascular Intensive Care Section Alberto Zangrillo, MD Section Director Elena Bignami, MD Tiziana Bove, MD Fabrizio Monaco, MD Annalisa Franco, MD Chiara Gerli, MD Giulia Maj, MD Federico Pappalardo, MD Mara Scandroglio, MD 9

Patronages Società Italiana di Cardiologia Interventistica BNK - Bundesverband Niedergelassener Kardiologen Arbeitsgemeinschaft Leitende Kardiologische Krankenhausärzte 10

Wednesday, February 10 th, 2016 ROOM MANZONI 12.30 Welcome light buffet lunch 13.00-19.00 Symposium BRS - BIORESORBABLE SCAFFOLDS Case presentation and lectures on new devices Chairmen: Martin B. Leon, Patrick W. Serruys, Gregg W. Stone Discussant: Nicolas Van Mieghem Keynote Lecture Patrick W. Serruys Imaging guided BRS implantation Which modality to pick? Azeem Latib DESolve NX 3yr clinical and imaging data Martin B. Leon DESolve scaffold differentiating characteristics Alexandre Abizaid Bioresorbable micro fibre scaffold changing the paradigm: The Manli Mirage program Patrick W. Serruys Novel interventional technologies - Tapered DES, BRS and beyond Martin B. Leon Novel polymer-free DES. Medtronic s answer to polymeric stents Martin Rothman Unity: Hybrid Biodegradable Stent Platform Azeem Latib DREAMS-2G: current data of the sirolimus eluting absorbable magnesium scaffold Michael Haude Amaranth: a new bioresorbable scaffold and future developments Antonio Colombo BRS in complex lesions and the structure of Absorb Compare Pieter C. Smits Imaging follow up with BRS Maciej Lesiak BRS in multivessel disease Ganesh Kumar The Boston Scientific Fully Resorbable Stent (FRS) Program Keith Dawkins 11

Thursday, February 11 th, 2016 MAIN HALL WASHINGTON 8.00-8.05 Welcome and Opening Address Antonio Colombo Chairman: Martin B. Leon Co-chairman: Carlo Di Mario 8.05-10.00 LIVE CASES FROM BONN, GERMANY University Hospital Commentators: Francesco Bedogni, Ted Feldman, Pedro Lemos, Ron Waksman Operators: Eberhard Grube, Georg Nickenig, Nikos Werner, Jan-Malte Sinning, Christoph Hammerstingl, Armin Welz, Fritz Mellert, Wolfgang Schiller Guest operators: Maurice Buchbinder, Marco Wainstein On-line factoids relevant to the cases presented: Francesco Giannini (Coordinator) Richard Jabbour, Hiroyoshi Kawamoto 10.00-10.30 Coffee break 10.30-12.30 LIVE CASES FROM MILAN, ITALY St. Raffaele Hospital Commentators: David Antoniucci, Susheel Kodali, Augusto Pichard, Patrizia Presbitero Operators: Antonio Colombo, Mauro Carlino, Alaide Chieffo, Filippo Figini, Azeem Latib, Matteo Montorfano On-line factoids relevant to the cases presented: Francesco Giannini (Coordinator) Richard Jabbour, Hiroyoshi Kawamoto 12.45-14.15 Lunch Symposia ROOM MANZONI DES 1 ROOM FOSCOLO TAVI 1 ROOM PORTA ROOM PARINI ROOM CLUB CTO ADJUNCTIVE TECHNOLOGIES LAA CLOSURE AND TRICUSPID 12

LUNCH SYMPOSIA - Thursday 12.45-14.15 DES 1 ROOM MANZONI Chairmen: Tullio Palmerini, Ron Waksman The Synergy Stent: optimal healing in complex patients Giulio Stefanini The COMBO dual therapy stent: from the REMEDEE registry to the REDUCE trial Giuseppe De Luca DES safety and DAPT: the Ultimaster DES Corrado Tamburino Abluminus DES + Sameer Dani 12.45-14.15 TAVI 1 ROOM FOSCOLO Chairmen: Bernhard Reimers, Nicolas Van Mieghem CoreValve Evolut R: setting new standards in TAVI without compromise Ganesh Manoharan Filter Science: the use of cerebral protection to prevent irreversible cerebral infarction during contemporary TAVI procedures Azeem Latib ACURATE neo : top-down deployment translates into stable, precise positioning and successful procedures: Symetis TAVI programme highlights Christian Hengstenberg Patient specific TAVI simulations, today and tomorrow Azeem Latib PORTICO transcatheter aortic heart valve: elegant technology drives optimal clinical outcomes Francesco Bedogni 12.45-14.15 CTO ROOM PORTA Chairmen: Jeffrey W. Moses, Georgios Sianos Two complex cases (anterograde & retrograde) Roberto Garbo Specific features of CTO wires and microcatheters Andrea Gagnor How can we simplify the most complex cases? Ferdinando Varbella Excimer laser catheter in CTO lesions Peter O Kane European perspective from the Euro CTO club Alfredo R. Galassi 13

LUNCH SYMPOSIA - Thursday 12.45-14.15 ADJUNCTIVE TECHNOLOGIES ROOM PARINI Chairmen: Patrick W. Serruys, Alan Yeung The role of lithoplasty for treatment of vascular disease Todd Jeffrey Brinton Rationale and value of plaque scoring with drug elution Bruno Scheller Percutaneous treatment for erectile dysfunction Giuseppe Massimo Sangiorgi When and where I use Impella device Carlo Briguori Cardioprotected PCI with the PiCSO Impulse System Antonio Colombo 12.45-14.15 LAA CLOSURE AND TRICUSPID ROOM CLUB Chairmen: Sergio Berti, Lutz Buellesfeld 4Tech TriCinch CE Mark and feasibility trial results Francesco Maisano Trialign: Transcatheter repair for functional tricuspid regurgitation Joachim Schofer Italian experience with Amplatzer technology Jacopo Andrea Oreglia Occlutech LAA Occluder: a novel device Eustaquio Onorato My experience with Watchman FLX: a next generation device Jochen Woehrle 14

Thursday, February 11 th, 2016 MAIN HALL WASHINGTON Chairman: Gregg W. Stone Co-chairman: Alexandre Abizaid 14.30-16.30 LIVE CASES FROM MILAN, ITALY St. Raffaele Hospital Commentators: Yaron Almagor, Carlo Briguori, Eulogio Garcia, Corrado Tamburino Operators: Antonio Colombo, Mauro Carlino, Alaide Chieffo, Azeem Latib, Matteo Montorfano On-line factoids relevant to the cases presented: Francesco Giannini (Coordinator) Richard Jabbour, Hiroyoshi Kawamoto 16.30-17.00 Coffee break 17.00-18.30 LIVE CASES FROM BONN, GERMANY University Hospital Commentators: Federico De Marco, Ghada Mikhail, Anna Sonia Petronio, Bernhard Reimers Operators: Eberhard Grube, Georg Nickenig, Nikos Werner, Jan-Malte Sinning, Christoph Hammerstingl, Armin Welz, Fritz Mellert, Wolfgang Schiller Guest operators: Maurice Buchbinder, Marco Wainstein On-line factoids relevant to the cases presented: Francesco Giannini (Coordinator) Richard Jabbour, Hiroyoshi Kawamoto 15

Friday, February 12 th, 2016 MAIN HALL WASHINGTON Chairman: Hendrik Treede Co-chairman: Gregg W. Stone 8.00-10.00 LIVE CASES FROM MILAN, ITALY St. Raffaele Hospital Commentators: Roxana Mehran, Sunao Nakamura, Seung Jung Park, Gennaro Sardella, Mohamed Ahmed Sobhy Operators: Antonio Colombo, Mauro Carlino, Alaide Chieffo, Azeem Latib, Matteo Montorfano On-line factoids relevant to the cases presented: Alaide Chieffo (Coordinator) Richard Jabbour, Hiroyoshi Kawamoto 10.00-10.30 Coffee break 10.30-12.30 LIVE CASES FROM BONN, GERMANY University Hospital Commentators: David Hildick-Smith, Karl Heinz Kuck, Francesco Maisano, Giuseppe Musumeci Operators: Eberhard Grube, Georg Nickenig, Nikos Werner, Jan-Malte Sinning, Christoph Hammerstingl, Armin Welz, Fritz Mellert, Wolfgang Schiller Guest operators: Maurice Buchbinder, Marco Wainstein On-line factoids relevant to the cases presented: Alaide Chieffo (Coordinator) Richard Jabbour, Hiroyoshi Kawamoto 12.45-14.15 Lunch Symposia ROOM MANZONI DES 2 ROOM FOSCOLO TAVI 2 ROOM PORTA ROOM PARINI ROOM CLUB MITRAL ESSENTIAL PHARMA INFORMATION FOR INTERVENTIONISTS FOCUS ON THE CLINICAL APPLICATION OF IC IMAGING MODALITIES: IVUS, OCT, IVUS-NIRS 16

LUNCH SYMPOSIA - Friday 12.45-14.15 DES 2 ROOM MANZONI Chairmen: Dariusz Dudek, Seung-Jung Park DES Onyx: the new option for the large vessel treatment Fabrizio Tomai MiStent: evolution of drug elution with crystalline Sirolimus Davide Capodanno BioFreedom DCS with 1 month DAPT: the new standard for high bleeding risk patients TBD SELUTION for stent like results in coronaries with DCB Ron Waksman 12.45-14.15 TAVI 2 ROOM FOSCOLO Chairmen: Alexandre Abizaid, Marco Barbanti Lithoplasty for aortic leaflet restoration Todd Jeffrey Brinton Hot from the R&D lab: innovative solutions from Direct Flow Medical Azeem Latib Manta - CE mark study with plug based closure device for large bore arteriotomies. A new era of large access closure Nicolas Van Mieghem The Lotus Valve: simplifying real world practice Raul Moreno Sapien 3: current experience Martin B.Leon 12.45-14.15 MITRAL ROOM PORTA Chairmen: Eustachio Agricola, Ted Feldman, Francesco Maisano Cardioband a new era of mitral valve repair Karl Heinz Kuck The first randomized, double-blind control trial on mitral valve therapy REDUCE-FMR Horst Sievert Percutaneous replacement of the mitral valve with the fully repositionable and retrievable Tendyne Bioprosthesis Neil Moat Mitralign: transcatheter repair for functional mitral regurgitation Azeem Latib The future of interventional mitral valve therapies: repair or replacement (from a surgeon s view) Hendrik Treede 17

LUNCH SYMPOSIA - Friday 12.45-14.15 ESSENTIAL PHARMA INFORMATION FOR INTERVENTIONISTS ROOM PARINI Clinical Crossroads on optimal acute and long term pharmacotherapy in PCI patients Chairmen: Giuseppe Musumeci, Marco Roffi Intravenous antiplatelet therapy Clinical Case: High risk ACS Giuseppe Tarantini GPIIb/IIIa inhibithors are the best solution Arnoud W.J. van t Hof Intravenous P2Y12 receptor inhibitors with powerful oral antiplatelets are the new best option Roxana Mehran Clinical Case: conclusion Giuseppe Tarantini Discussion Oral antiplatelet therapy Clinical Case: ACS in elderly patients Alfredo Marchese New P2Y12 inhibitors are the right choice Alberto Menozzi Optimal duration of oral antiplatelet therapy Dominick J. Angiolillo Clinical Case: conclusion Alfredo Marchese Discussion Anti-ischemic therapy Clinical Case: Incomplete revascularization Pedro Lemos Medical therapy optimization with new anti-ischemic drugs Giuseppe Musumeci Beneficial effects of heart rate reduction on residual ischemia Cosmo Godino Clinical Case: conclusion Pedro Lemos Discussion 18

LUNCH SYMPOSIA - Friday 12.45-14.15 FOCUS ON THE CLINICAL APPLICATION OF IC IMAGING MODALITIES: IVUS, OCT, IVUS-NIRS ROOM CLUB Chairmen: Carlo Di Mario, Francesco Prati OCT basics: interpretation of coronary images pre and post-intervention Giulio Guagliumi Imaging modalities to guide elective coronary interventions Antonio Bartorelli Imaging modalities to guide coronary intervention in the acute coronary syndromes Francesco Prati Imaging modalities to guide complex interventions Augusto Pichard Imaging modalities to guide bio-absorbable scaffolds Corrado Tamburino How and when to use IVUS during CTO Andrea Garbo 19

Y coordinates and develops cardiovascular research Y contributes to the formation of professional figures in this field Y promotes meetings, seminars and conferences in accordance with the aims of the foundation www.fondevidence.org www.fondevidence.org Fondazione Evidence per Attività e Ricerche Cardiovascolari - Onlus Sede Legale: Via Donizetti, 30-20122 Milano - Italy Ph. +39 335 67 51 553 Y mail: fondevidence@gmail.com

Friday, February 12 th, 2016 MAIN HALL WASHINGTON Chairman: Antonio Colombo Co-chairman: Jeffrey W. Moses 14.30-16.00 LIVE CASES FROM BONN, GERMANY University Hospital Commentators: Paolo Denti, Oscar Mendiz, Horst Sievert, Constantin Von zur Mühlen Operators: Eberhard Grube, Georg Nickenig, Nikos Werner, Jan-Malte Sinning, Christoph Hammerstingl, Armin Welz, Fritz Mellert, Wolfgang Schiller Guest operators: Maurice Buchbinder, Marco Wainstein On-line factoids relevant to the cases presented: Alaide Chieffo (Coordinator) Richard Jabbour, Hiroyoshi Kawamoto 16.00-16.30 Coffee break 16.30-18.00 LIVE CASES FROM NEW YORK, USA Columbia University Commentators: Antonio Bartorelli, Susheel Kodali, Ganesh Manoharan, Nicolas Van Mieghem Operators: Dimitrios Karmpaliotis, William Nicholson On-line factoids relevant to the cases presented: Alaide Chieffo (Coordinator) Richard Jabbour, Hiroyoshi Kawamoto 21

Saturday, February 13 th, 2016 MAIN HALL WASHINGTON Chairmen of the day: Eberhard Grube, Martin B. Leon 8.30-9.30 LIVE CASES FROM MILAN, ITALY Columbus Hospital Heart Center Commentators: Alexandre Abizaid, Hazem Khamis, Ghada Mikhail, Seung Jung Park, Francesco Versaci Operators: Antonio Colombo, Azeem Latib, Gloria Melzi Guest operator: Sunao Nakamura On-line factoids relevant to the cases presented: Alaide Chieffo (Coordinator) Richard Jabbour, Hiroyoshi Kawamoto 9.30-11.00 CASES PRESENTATION AND DEBATE 11.00-12.30 LIVE CASES FROM MILAN, ITALY Columbus Hospital Heart Center Commentators: Alexandre Abizaid, Hazem Khamis, Ghada Mikhail, Seung Jung Park, Francesco Versaci Operators: Antonio Colombo, Azeem Latib, Gloria Melzi Guest operator: Sunao Nakamura On-line factoids relevant to the cases presented: Alaide Chieffo (Coordinator) Richard Jabbour, Hiroyoshi Kawamoto 12.30 Closing remarks and JIM 2017 announcement 22

Scientific Information Language English is the official language of the Congress. No simultaneous translation is available. Cases presentation and Posters Recorded procedures Have a chance to show your best success or to discuss your worst complications in front of an outstanding panel in the Main Arena. Saturday morning will be devoted to cases review (10 minutes each, including Q&A) from Faculty and Attendance. Posters Selected posters will be displayed in the Congress Area throughout the Meeting. Computer Center A Computer Center will be available in the Congress Area. To allow a smooth running of sessions, Speakers are requested to contact this center and hand in their presentation at least one hour before the beginning of their session or the previous afternoon for the morning sessions. 23 TV direction and coordination by: Mr. Sandro Alli Coordination of technical equipment by: Mr. Paolo Torreggiani - LVS Solution Website by: Extra.it Tecnomovie EDP Management by: JOY Solutions Expert

General Information Organizing Secretariat Victory Project Congressi Via C. Poma, 2-20129 Milan - Italy Phone: +39 02 89 05 35 24 Fax: +39 02 20 13 95 e-mail: info@victoryproject.it Secretariat on Site Secretariat and Registration Desk at Congress Venue will be on duty from February 10 through 13. February 10 February 11 February 12 February 13 Opening hours 12.00 am - 7.30 pm 7.00 am - 7.00 pm 7.30 am - 6.30 pm 8.00 am - 1.00 pm Coffee and refreshment Coffee and refreshment will be organized in the Exhibition area. Lunch Buffet for Exhibitors Buffet lunch will be served in Restaurant La Brasserie subject to presentation of the daily ticket. 24

General Information Symposia for Physicians, Industry Professionals, Fellows and Nurses Symposia will be organized in Room Manzoni, Room Foscolo, Room Porta, Room Parini and Room Club. Participation is subject to presentation of the daily ticket (food and beverages included). Technical exhibition An exhibition of scientific and technical equipment will be organized in the Congress Area. Interested companies are kindly requested to contact the Organizing Secretariat in order to receive the exhibitors kit with full information. Certificate of attendance A certificate of attendance will be given to all registered participants upon presentation of their badge at the Secretariat Desk on Saturday, February 13, 2016. EBAC CME Accreditation JIM 2016 Scientific Program has been submitted for accreditation by the European Board of Accreditation in Cardiology (EBAC). 25

Registration Registration fees After Nov. 30 On site Physicians 950,00 E 1.000,00 E Special fare for GISE Members 600,00 E 700,00 E Fellows, nurses, technicians 320,00 E 320,00 E Industry Professionals (not having a stand) 950,00 E 1.000,00 E Exhibitors 465,00 E 465,00 E (having a stand) Symposium on BRS (on Wednesday 10) included included (prices are in Euro and include VAT) Full registration fee for Physicians, Industry Professionals, Fellows, Nurses and Technicians includes: Admission to all Scientific Sessions Coffee and refreshment All Symposia (lunch included) Entrance to the Exhibition Congress kit Registration fee for Exhibitors includes: Admission to Live Case Sessions Buffet lunch Congress kit Coffee and refreshment Entrance to the Exhibition Only registered participants are allowed to attend scientific sessions. Participants are requested to wear their badge for all the Congress events. After January 30, 2016 only registrations on site at the New Registrations Desk in the Congress Venue will be accepted. 26

Registration 2 easy ways to register @ e-mail: info@victoryproject.it : on line: www.jim-vascular.com Payment information Credit Cards: CartaSì - Mastercard - Visa - American Express Bank Transfer to: Victory Project Congressi Srl Unicredit Banca Agenzia 21903 Via C. Poma - Milan, Italy Account n. 9340484 IBAN code IT 58 Z 02008 09403 00000 9340484 SWIFT code UNCRIT M1L41 For this kind of payment, participants are absolutely requested to notify the bank of their complete name and address and the reason for the payment. Bank expenses must be on participant s charge. Please note that only registrations accompanied by the relevant payment will be processed. Cancellations and refunds Cancellations received in writing by the Organizing Secretariat by December 30, 2015 will be subject to a 30% penalty. No refund will be given after this date. 27

Hotel Accommodation All those interested in making hotel reservation are kindly requested to contact: VICTORY PROJECT CONGRESSI or to process hotel reservation on line. You are kindly requested to check updated availability with the Organizing Secretariat. HOTEL Double used SINGLE DOUBLE Address Milan Marriott Hotel IIII SOLD OUT SOLD OUT Via Washington, 66-20146 Milano (congress venue) Hotel Capitol Milano IIII SOLD OUT SOLD OUT Via Domenico Cimarosa, 6-20144 Milano Hotel Cristoforo Colombo IIII 209,00 E 239,00 E Corso Buenos Aires, 3-20124 Milano Mini Hotel Tiziano IIII SOLD OUT SOLD OUT Via Tiziano, 6-20145 Milano Hotel Wagner IIII 175,00 E 210,00 E Via Michelangelo Buonarroti, 13-20149 Milano UNA Hotel Cusani IIII SOLD OUT SOLD OUT Via Cusani, 13-20121 Milano UNA Hotel Tocq IIII 184,00 E 204,00 E Via A. De Tocqueville, 7/D - 20154 Milano UNA Hotel Century IIII 180,00 E 200,00 E Via Fabio Filzi, 25/b - 20124 Milano NH Hotel Touring IIII 169,00 E 189,00 E Via Ugo Tarchetti, 2-20121 Milano NH Hotel Nhow IIII 179,00 E 199,00 E Via Tortona, 35-20144 Milano NH Hotel Collection President IIII SOLD OUT SOLD OUT Largo Augusto,10-20121 Milano The above listed rates are expressed in Euro and are per room per night, including continental breakfast, services and taxes. Total prepayment of minimum 3 nights (arrival February 10, departure February 13) and a booking fee of E 25,00 per room are requested. We remind you that a city tax of E 5,00 per person per night (requested directly by the City Council of Milan and subject to possible increase in 2016) shall be paid in cash by each guest to the hotel at the moment of check out. 28

Hotel Map Payment information Credit Cards: CartaSì - Mastercard - Visa - American Express Bank Transfer to: Victory Project Congressi Srl UniCredit Banca - Agenzia 21903 - Via C. Poma, Milan, Italy Account n. 9340484 IBAN code: IT 58 Z 02008 09403 00000 9340484 SWIFT code: UNCRIT M1L41 Cancellations and refunds No refund will be given for hotel rates. All changes must be submitted in writing to: Victory Project Congressi by December 30, 2015. 29

On-line registration and booking You can register and book your hotel accommodation on line on: www.jim-vascular.com For group registration and for any further assistance, you are invited to contact the Organizing Secretariat at info@victoryproject.it Payment information Credit Cards: CartaSì - Mastercard - Visa - American Express Bank Transfer to: Victory Project Congressi Srl Unicredit Banca Agenzia 21903 Via C. Poma - Milan, Italy Account n. 9340484 IBAN code IT 58 Z 02008 09403 00000 9340484 SWIFT code UNCRIT M1L41 For this kind of payment, participants are absolutely requested to notify the bank of their complete name and address and the reason for the payment. Bank expenses must be on participant s charge. Please note that only registrations and hotel reservation accompanied by the relevant payment will be processed. 30

How to get to Milan Marriott Hotel Milan Marriott Hotel Via Washington, 66 20146 Milan - Italy Phone +39 02 48 521 By Plane From the airports of Milan Malpensa and Milan Linate you can take a shuttle bus to the Central Station. Or by taxi, estimated fare: - from Malpensa: 90 (one way) - From Linate: 35 (one way) By Train The Milan Central Station is about 8 km away from the hotel. By Car From the Freeway East (Tangenziale Est) exit Via Certosa and follow signs to Fiera Milano City. Once in Piazza Giulio Cesare, turn right to Piazza Piemonte. From there, take Via Washington, where the hotel is located. By Underground The nearest underground station is Wagner (red line), at about 1 km from the hotel. By Bus Bus line 61 Parking A private parking is available. Fee: 2,10/hour, 15/day 31

JOINT INTERVENTIONAL MEETING WE LOOK FORWARD TO WELCOMING ALL OUR FRIENDS AT JIM 2016 IN MILAN! ORGANIZING SECRETARIAT Victory Project Congressi Via C. Poma, 2-20129 Milan - Italy Phone +39 02 89 05 35 24 Fax +39 02 20 13 95 E-mail info@victoryproject.it CONGRESS VENUE Milan Marriott Hotel Via Washington, 66 20146 Milan - Italy FURTHER INFORMATION www.jim-vascular.com