THURSDAY, FEBRUARY 13th, 2011

THURSDAY, FEBRUARY 13th, 2011

Faculty Members Course Directors Antonio COLOMBO, MD Eberhard GRUBE, MD Martin B. LEON, MD Jeffrey W. MOSES, MD Carlo DI MARIO, MD Course Co-Directors Alexandre ABIZAID, MD Osamu KATOH, MD Kazuaki MITSUDO, MD Gregg W. STONE, MD Takahiko SUZUKI, MD Useful Addresses Course Coordinator Marina Schenetti Centro Cuore Columbus - Columbus Hospital Phone +39 02 48 12 920 Fax +39 02 48 19 34 33 e-mail info@emocolumbus.it www.centrocuoremilano.com Live Satellite Transmissions From Milan From Bonn From London Organizing Secretariat Victory Project Congressi Via C. Poma, 2 20129 Milan - Italy Phone +39 02 89 05 35 24 Fax +39 02 20 13 95 e-mail info@victoryproject.it Presented by COLUMBUS HOSPITAL CENTER Milan, Italy ROYAL BROMPTON & HAREFIELD NHS TRUST London, UK ST. RAFFAELE HOSPITAL Milan, Italy UNIVERSITY HOSPITAL BONN Bonn, Germany Congress Venue Ergife Palace Hotel Via Aurelia, 619 00165 Rome - Italy Phone +39 06 66 441 www. ergifepalacehotel.com Visit our website for registration on-line Program updated to ( ) January 27 th, 2011 2 3

Welcome We are very pleased to welcome you in Rome again! This year we will give the usual emphasis to live cases. We will demonstrate what we mean for optimal implantation of a drug eluting stent. Ultimately we believe that this strategy will further improve the safety and performance of these devices. Live demonstrations will include treatment of adult valvular heart disease, structural heart disease and selected peripheral interventions. The meeting maintains its format with State of the Art lectures given by experts in the field. Lunch and evening symposia fulfil this target. This year we have again live transmission on Saturday morning in order to maintain a well-balanced distribution of live cases throughout the entire meeting. More emphasis and expansion are given to those sessions in which attendees can present and discuss cases. Once again the Meeting will take place in Rome, but in a new location: the Ergife Palace Hotel. It combines a confortable accommodation solution with a large and efficient Congress Centre. Antonio Colombo, MD Eberhard Grube, MD Faculty Members Invited Faculty ABIZAID ALEXANDRE, MD Sao Paulo - Brazil ALBIERO REMO, MD Ome, BS - Italy ALFIERI OTTAVIO, MD Milan - Italy ALMAGOR YARON, MD Jerusalem - Israel ANGIOLILLO DOMINICK, MD Jacksonville, FL - USA ANTONIUCCI DAVID, MD Florence - Italy BARTORELLI ANTONIO, MD Milan - Italy BERSIN ROBERT M., MD Seattle, WA - USA BIJUKLIC KLAUDIJA, MD Innsbruck - Austria BOLOGNESE LEONARDO, MD Arezzo - Italy BORTONE ALESSANDRO, MD Bari - Italy BRIGUORI CARLO, MD Naples - Italy BUELLESFELD LUTZ, MD Bern - Switzerland CAMENZIND EDOARDO, MD Geneva - Switzerland CARRIE DIDIER, MD Toulouse - France DANGAS GEORGE, MD New York, NY - USA DANZI GIAN BATTISTA, MD Milan - Italy DHARMADHIKARI ANIRUDDHA, MD Nashik - India DI MARIO CARLO, MD London - UK DI SCIASCIO GERMANO, MD Rome - Italy DUDEK DARIUSZ, MD Krakow - Poland FELDMAN TED, MD Evanston, IL - USA FERES FAUSTO, MD Sao Paulo - Brazil FISCELLA ANTONIO, MD Catania - Italy FRANZEN OLAF, MD Hamburg - Germany FRASER DOUGLAS, MD Manchester - UK GALASSI ALFREDO, MD Catania - Italy GARCIA EULOGIO, MD Madrid - Spain GASPARDONE ACHILLE, MD Rome - Italy GOKTEKIN OMER, MD Eskisehir - Turkey GOLDBERG STEVE, MD Seattle, WA - USA GRINFELD LILIANA, MD Buenos Aires - Argentina GUAGLIUMI GIULIO, MD Bergamo - Italy HASDAI DAVID, MD Petah, Tikva - Israel HIJAZI ZIYAD, MD Chicago, IL - USA KATOH OSAMU, MD Toyoashi Aichi - Japan 4 5

Faculty Members Faculty Members Invited Faculty Invited Faculty KATZEN BARRY T., MD Miami, FL - USA NEUMANN FRANZ-JOSEF, MD Bad Krozingen - Germany SARDELLA GENNARO, MD Rome - Italy USSIA GIAN PAOLO, MD Catania - Italy KODALI SUSHEEL, MD New York, NY - USA OCHIAI MASAHIKO, MD Kanagawa - Japan SCHOFER JOACHIM, MD Hamburg - Germany VAHANIAN ALEC, MD Paris - France KRUCOFF MITCHELL W., MD Durham, NC - USA OSTOJIC MIODRAG, MD Belgrade - Serbia SCHULER GERHARD, MD Leipzig - Germany VALSECCHI ORAZIO, MD Bergamo - Italy KUCK KARL HEINZ, MD Hamburg - Germany PETRONIO ANNA SONIA, MD Pisa - Italy SIEVERT HORST, MD Frankfurt - Germany VAN GARSSE LEEN, MD Liège - Belgium LABORDE JEAN CLAUDE, MD London - UK PIAZZA NICOLO, MD Munich - Germany SILBER SIGMUND, MD Munich - Germany VERSACI FRANCESCO, MD Rome - Italy LEON MARTIN B., MD New York, NY - USA PICHARD AUGUSTO, MD Washington, DC - USA STANKOVIC GORAN, MD Belgrade - Serbia WAINSTEIN MARCO, MD Sao Paulo - Brazil MAISANO FRANCESCO, MD Milan - Italy POPMA JEFFREY, MD Boston, MA - USA STONE GREGG W., MD New York, NY - USA WAKSMAN RON, MD Washington, DC - USA MARRA SEBASTIANO, MD Turin - Italy POTDAR ANIL, MD Mumbai - India TAMBURINO CORRADO, MD Catania - Italy WENDLER OLAF London - UK MASSETTI MASSIMO, MD Caen - France PRATI FRANCESCO, MD Rome - Italy TAN HUAY CHEEM, MD Singapore WESSELY RAINER, MD Duisburg - Germany MEHRAN ROXANA, MD New York, NY - USA PRESBITERO PATRIZIA, MD Milan - Italy THOMAS MARTYN, MD London - UK WILSON ROBERT, MD Minneapolis, MN USA MEREDITH IAN, MD Melbourne - Australia RAIMONDI MAURIZIO, MD Pavia - Italy TOBIS JONATHAN, MD Los Angeles, CA - USA WINDECKER STEPHAN, MD Bern - Switzerland MEUCCI FRANCESCO, MD Florence - Italy RASTAN ARDAWAN, MD Leipzig - Germany TRANI CARLO, MD Rome - Italy WOLF CHRISTOPHER, MD Wien - Austria MIKHAIL GHADA, MD London - UK REIMERS BERNHARD, MD Mirano, VE - Italy TSUCHIKANE ETSUO, MD Toyohashi, Aichi - Japan MINTZ GARY, MD New York, NY - USA RIBEIRO EXPEDITO, MD Sao Paulo - Brazil MORICE MARIE CLAUDE, MD Massy - France RIBICHINI FLAVIO L., MD Verona - Italy MOSES JEFFREY W., MD New York, NY - USA RIHAL CHARANJIT S., MD Rochester, MN - USA MOUSSA ISSAM, MD New York, NY - USA RUBBOLI ANDREA, MD Bologna - Italy NAPODANO MASSIMO, MD Padova - Italy SANGIORGI GIUSEPPE MASSIMO, MD Modena - Italy 6 7

Patronages ASSOCIAZIONE NAZIONALE MEDICI CARDIOLOGI OSPEDALIERI (ANMCO) SOCIETÀ ITALIANA DI CARDIOLOGIA INVASIVA DEUTSCHE GESELLSCHAFT FÜR KARDIOLOGIE HERZ - UND KREISLAUFFORSCHUNG BNK BUNDESVERBAND NIEDERGELASSENER KARDIOLOGEN E. V. ARBEITSGEMEINSCHAFT LEITENDER KARDIOLOGISCHER KRANKENHAUSÄRZTE 9

Faculty Members Columbus Hospital, Milan FACULTY AND OPERATORS Antonio Colombo, MD Bruno Damascelli, MD Leo Finci, MD Cosmo Godino, MD Azeem Latib, MD Gloria Melzi, MD Vladimira Ticha, MD Fellow and Research Associates Joanne Shannon, MD Kensuke Takagi, MD University Hospital, Bonn FACULTY AND OPERATORS Eberhard Grube, MD Lars Lickfett, MD Georg Nickenig, MD Jan Malte Sinning, MD Nikos Werner, MD ERGIFE Palace Hotel Cardiology and Intensive Coronary Care Sections Raffaella Alpago, MD Giancarlo Biagi, MD Federica Della Rocca, MD ANAESTHESIOLOGY DEPARTMENT Romeo Arienta, MD Massimo Croci, MD Stefano Fattore, MD Pierluigi Villa, MD CARDIOVASCULAR SURGERY DEPARTMENT Wolfgang Schüller, MD Armin Welz, MD ANAESTHESIOLOGY DEPARTMENT Andreas Hoeft, MD Faculty Members St. Raffaele Hospital, Milan FACULTY AND OPERATORS Antonio Colombo, MD Mauro Carlino, MD Alfredo Castelli, MD Alaide Chieffo, MD Cosmo Godino, MD Azeem Latib, MD Matteo Montorfano, MD Fellows and Research Associates Francesco Arioli, MD Alfonso Ielasi, MD Marco Mussardo, MD CARDIOTHORACIC DEPARTMENT Ottavio Alfieri, MD - Director Cardiac Surgery Section Ottavio Alfieri, MD - Section Director Irina Arendar, MD Stefano Benussi, MD Andrea Blasio, MD Alessandro Castiglioni, MD Micaela Cioni, MD Michele De Bonis, MD Paolo Denti, MD Enrica Dorigo, MD David Ferrara, MD Andrea Fumero, MD Antonio Grimaldi, MD Giuseppe Iaci, MD Giovanni La Canna, MD Elisabetta La Penna, MD Francesco Maisano, MD Stefano Moriggia, MD Simona Nascimbene, MD Maria Grazia Pala, MD Alessandra Rossodivita, MD Maurizio Taramasso, MD Alessandro Verzini, MD Cardiology and Intensive Coronary Care Sections Alberto Margonato, MD - Section Director Carlo Ballarotto, MD Alberto Cappelletti, MD Andrea Conversano, MD Andrea Macchi, MD Michele Opizzi, MD Marco Papa, MD Giuseppe Pizzetti, MD Vascular Surgery Section Roberto Chiesa, MD - Section Director Domenico Astore, MD Renata Castellano, MD Efrem Civilini, MD Laura Dordoni, MD Gloria Esposito, MD Enrico Maria Marone, MD Massimiliano Marrocco Trischitta, MD Germano Melissano, MD Yamume Tshomba, MD Anaesthesiology and Cardiovascular Intensive Care Section Alberto Zangrillo, MD - Section Director Elena Bignami, MD Tiziana Bove, MD Remo Daniel Covello, MD Annalisa Franco, MD Clara Gerli, MD Silvio Magrin, MD Giulia Maj, MD Giovanni Marino, MD Federico Pappalardo, MD Mara Scandroglio, MD 10 11

Thursday, February 10th, 2011 MAIN HALL LEONARDO 8.15-8.20 Welcome and Opening Address Chairman: Martin B. Leon Co-chairman: Carlo Di Mario 8.20-10.00 LIVE CASES FROM MILAN, ITALY St. Raffaele Hospital Commentators: Ted Feldman, Miodrag Ostojic, Corrado Tamburino, Martyn Thomas, Ron Waksman Operators: Antonio Colombo, Mauro Carlino, Alaide Chieffo, Cosmo Godino, Giovanni La Canna, Azeem Latib, Francesco Maisano, Matteo Montorfano Guest operator: Horst Sievert On-line factoids relevant to the cases presented: Francesco Arioli, Alfonso Ielasi, Marco Mussardo 10.00-10.30 Coffee break 10.30-12.30 LIVE CASES FROM BONN, GERMANY University Hospital Bonn Commentators: Alexandre Abizaid, Alfredo Galassi, Steve Goldberg, Jean Claude Laborde, Ian Meredith Operators: Eberhard Grube, Lars Lickfett, Georg Nickenig, Jan Malte Sinning, Nikos Werner Guest operators: Lutz Buellesfeld, Gregg W. Stone, Marco Wainstein On-line factoids relevant to the cases presented: Francesco Arioli, Alfonso Ielasi, Marco Mussardo 12.45-14.15 Working Lunch Thursday, February 10th, 2011 12.45-14.15 Lunch Symposium - ROOM MICHELANGELO ADVANCES IN TAVI 2011 (PART 1) Chairmen: Jean Claude Laborde, Gerhard Schuler 12.45 Recent evolution and innovation in Edwards SAPIEN XT valve family and delivery systems Alec Vahanian 13.00 Global clinical update on the Edwards TAVI registries and PARTNER IDE trial Martyn Thomas 13.15 Global update on CoreValve registries outside US Stephan Windecker 13.30 Update on US pivotal Medtronic-CoreValve trial Jeffrey Popma 13.45 How to make TAVI safer? New valves and the use of ancillary devices Alexandre Abizaid 14.00 Questions & Answers 12.45-14.15 Lunch Symposium - ROOM TIZIANO NEW DES: A NEW STEP FORWARD? (PART 1) Chairmen: Ian Meredith, Ron Waksman 12.45 Promus element: solution for complex patients Marie Claude Morice 13.00 New CID polymer free reservoirs and bio inducer DES Alexandre Abizaid 13.15 CRE8: preclinical experience and clinical plan Didier Carrie 13.30 Nobori stent: real life clinical outcomes Gian Battista Danzi 13.45 Advancing safety beyond surface-coated stents Christopher Wolf 14.00 Questions & Answers 12.45-14.15 Lunch Symposium - ROOM GIOTTO UPDATE ON PERCUTANEOUS MITRAL VALVE THERAPY Chairmen: Ted Feldman, Gian Paolo Ussia 12.45 The European experience with mitral valve Olaf Franzen 13.00 Ventricular reshaping with GDS Accucinch system Joachim Schofer 13.15 Percutaneous mitral valve therapy: update on clinical results and real life experience Ted Feldman 13.30 An update on Mitralign First in Man Study Karl Heinz Kuck 13.45 Mitral anulus therapy: update on Carillon Steve Goldberg 14.00 Questions & Answers 12 13

14 Thursday, February 10th, 2011 MAIN HALL LEONARDO Chairman: Martin B. Leon Co-chairman: Carlo Di Mario 14.30-16.30 LIVE CASES FROM MILAN, ITALY St. Raffaele Hospital Commentators: Antonio Bartorelli, Sebastiano Marra, Ghada Mikhail, Bernhard Reimers, Sigmund Silber, Goran Stankovic Operators: Antonio Colombo, Mauro Carlino, Alaide Chieffo, Cosmo Godino, Giovanni La Canna, Azeem Latib, Matteo Montorfano Guest operators: Gary Mintz, Jeffrey W. Moses, Horst Sievert On-line factoids relevant to the cases presented: Francesco Arioli, Alfonso Ielasi, Marco Mussardo 16.30-17.00 Coffee break 17.00-18.30 LIVE CASES FROM BONN, GERMANY University Hospital Bonn Commentators: Yaron Almagor, David Antoniucci, Robert M. Bersin, Ziyad Hijazi, Expedito Ribeiro, Joachim Schofer Operators: Eberhard Grube, Lars Lickfett, Georg Nickenig, Jan Malte Sinning, Nikos Werner Guest operators: Lutz Buellesfeld, Eulogio Garcia, Marco Wainstein On-line factoids relevant to the cases presented: Francesco Arioli, Alfonso Ielasi, Marco Mussardo 18.45-20.45 Cocktail Symposia Thursday, February 10th, 2011 18.45-20.45 Cocktail Symposium - ROOM TIZIANO HOW TO OPTIMIZE PRIMARY ANGIOPLASTY endorsed by Centro per la Lotta contro l Infarto - Fondazione ONLUS Chairmen: Francesco Prati, Francesco Versaci 18.45 The impact of intracoronary imaging modalities Giuseppe Massimo Sangiorgi 19.00 Reduction of thrombus burden by aspiration or mechanical thrombectomy David Antoniucci 19.15 Reduction of thrombus with local coronary infusion of IIb/IIIa inhibitors Francesco Prati 19.30 The ideal stent surface for AMI Ron Waksman 19.45 Still a role for upstream drug strategy? Dariusz Dudek 20.00 Optimization of platelet inhibition with the tienopyridine Andrea Rubboli 20.15 Stent choice in primary percutaneous coronary intervention Edoardo Camenzind 20.30 Self-apposing stent in AMI: rationale and clinical evidence Corrado Tamburino 20.45 Questions & Answers 18.45-20.45 Cocktail Symposium - ROOM GIOTTO PCI FROM RADIAL APPROACH Chairmen: Giulio Guagliumi, Issam Moussa 18.45 Advanced tips and tricks for radial approach Douglas Fraser 19.00 Radial approach challenge for coronary interventions Orazio Valsecchi 19.15 Radial approach in STEMI Carlo Trani 19.30 Questions & Answers NEW THERAPIES FOR CARDIOGENIC SHOCK Chairmen: Leonardo Bolognese, Giuseppe Massimo Sangiorgi 19.45 Cardiogenic shock complicating acute coronary syndromes: how are we doing? David Hasdai 20.00 Back from irriversibility: the ultra advanced life support program Maurizio Raimondi 20.15 Back from irriversibility: how to build-up a therapeutic synergy team Massimo Massetti 20.30 Questions & Answers 15

Thursday, February 10th, 2011 Thursday, February 10th, 2011 18.45-20.45 Cocktail Symposium - ROOM MICHELANGELO SEPTEMBER 21-25, 2010 WALTER E. WASHINGTON CONVENTION CENTER W ASHINGTON, DC TCT AT JIM 2011 BACK TO THE BASICS: A PATIENT FOCUSED APPROACH PART 1 Evaluation and treatment of patients with valvular heart disease Chairman: Martin B. Leon Panel: Ted Feldman, Olaf Franzen, Susheel Kodali, Francesco Maisano, Massimo Napodano, Nicolo Piazza, Olaf Wendler AORTIC STENOSIS Chairmen: Martin B. Leon, Olaf Wendler 18.45 Case I - High risk patient with severe aortic stenosis Nicolo Piazza 18.50 Review of the TAVI clinical evidence: PARTNER, and registry reports Susheel Kodali 19.00 Who should (and should not) have TAVI in 2011: the art of patient selection Martin B. Leon 19.10 Discussion TAVI controversies: clinical issues, reimbursement, and next steps Discussants: Ted Feldman, Olaf Franzen, Susheel Kodali, Francesco Maisano, Massimo Napodano, Nicolo Piazza 19.50 Discussion MitraClip controversies: clinical indications and outcomes, physician training considerations Discussants: Susheel Kodali, Martin B. Leon, Francesco Maisano, Gregg W. Stone, Olaf Wendler PART 2 Acute MI: what have we learned? Chairman: Gregg W. Stone Panel: George Dangas, Giulio Guagliumi, Susheel Kodali, Martin B. Leon, Roxana Mehran, Franz-Josef Neumann 20.05 Case III - Patient with acute anterior MI and large thrombus burden Massimo Napodano 20.10 Bivalirudin vs. GP II b/ IIIA: which drug and for whom? Roxana Mehran 20.15 Clopidogrel, Ticagralor or Prasugrel - which drug and for whom? Franz-Josef Neumann 20.25 DES vs. BMS: which stent and for whom? George Dangas 20.30 Thrombus aspiration and/or IC pharmacotherapy: which therapy and for whom? Gregg W. Stone 20.40 Discussion STEMI controversies: drugs, devices, and guidelines Discussants: George Dangas, Giulio Guagliumi, Martin B. Leon, Roxana Mehran, Massimo Napodano, Franz-Josef Neumann, Nicolo Piazza MITRAL REGURGITATION Chairmen: Ted Feldman, Olaf Franzen 19.25 Case II High risk patient with severe functional mitral regurgitation Olaf Franzen 19.30 Who should (and should not) have MitraClip in 2011: the art of patient selection Francesco Maisano 19.40 Review of the MitraClip clinical evidence: EVEREST and beyond Ted Feldman 16 17

Friday, February 11th, 2011 MAIN HALL LEONARDO Chairman: Gregg W. Stone Co-chairman: Stephan Windecker 8.00-10.00 LIVE CASES FROM MILAN, ITALY Columbus Hospital Commentators: Gian Battista Danzi, Aniruddha Dharmadhikari, Franz-Josef Neumann, Bernhard Reimers, Flavio L. Ribichini Operators: Antonio Colombo, Bruno Damascelli, Leo Finci, Cosmo Godino, Azeem Latib, Gloria Melzi Guest operator: Jonathan Tobis On-line factoids relevant to the cases presented: Alaide Chieffo, Francesco Arioli, Alfonso Ielasi 10.00-10.30 Coffee break 10.30-12.30 LIVE CASES FROM BONN, GERMANY University Hospital Bonn Commentators: Remo Albiero, Liliana Grinfeld, Giulio Guagliumi, Sigmund Silber, Huay Cheem Tan Operators: Eberhard Grube, Georg Nickenig, Lars Lickfett, Jan Malte Sinning, Nikos Werner Guest operators: Lutz Buellesfeld, Marco Wainstein On-line factoids relevant to the cases presented: Alaide Chieffo, Francesco Arioli, Alfonso Ielasi 12.45-14.15 Working Lunch Friday, February 11th, 2011 12.45-14.15 Lunch Symposium - ROOM MICHELANGELO TIPS & TRICKS ON PERCUTANEOUS VALVE Chairmen: Antonio Bartorelli, Stephan Windecker 12.45 Recent learnings and case examples using the Edwards SAPIEN XT THV Leen van Garsse 13.05 My rules for a perfect CoreValve TAVI procedure Jean Claude Laborde 13.20 Selected case presentation: emphasis on complications Augusto Pichard 13.35 My rules for a perfect SAPIEN TAVI procedure Olaf Wendler 13.50 Tips & tricks for subclavion approach Anna Sonia Petronio 14.05 Questions & Answers 12.45-14.15 Lunch Symposium - ROOM TIZIANO NEW DES: A NEW STEP FORWARD? (PART 2) Chairmen: Giulio Guagliumi, Marie Claude Morice 12.45 Treating the diabetes mellitus patient Eulogio Garcia 13.00 Is Xience a different DES? Flavio L. Ribichini 13.15 Resolute: current result and future perspectives Martin B. Leon 13.30 Polymer-free DES: a real step forward? Ian Meredith 13.45 Safety and efficacy of DES. What are the standards? Rainer Wessely 14.05 Questions & Answers 12.45-14.15 Lunch Symposium - ROOM GIOTTO PERIVALVULAR LEAK, PFO CLOSURE AND LEFT ATRIAL APPENDAGE Chairmen: Achille Gaspardone, Horst Sievert 12.45 Indications, techniques and results of PFO closure 2011 Ziyad Hijazi 13.00 Procedural and imaging considerations in Paravalvular Leak Closure Charanjit S. Rihal 13.15 Importance of acute results Charanjit S. Rihal 13.30 My approach to perivalvular leak closure Eulogio Garcia 13.45 Left atrial appendage Francesco Meucci 14.00 Questions & Answers 18 19

Friday, February 11th, 2011 MAIN HALL LEONARDO Chairman: Jeffrey W. Moses Co-chairman: Martyn Thomas 14.30-16.00 LIVE CASES FROM MILAN, ITALY Columbus Hospital Commentators: Ottavio Alfieri, Antonio Fiscella, Omer Goktekin, Gary Mintz, Issam Moussa Operators: Antonio Colombo, Leo Finci, Cosmo Godino, Gloria Melzi Guest operators: Mitchell Krucoff, Jonathan Tobis On-line factoids relevant to the cases presented: Alaide Chieffo, Francesco Arioli, Alfonso Ielasi 16.00-16.30 Coffee break 16.30-18.00 LIVE CASES FROM BONN, GERMANY University Hospital Bonn Commentators: Germano Di Sciascio, Fausto Feres, Olaf Franzen, Marie Claude Morice, Patrizia Presbitero Operators: Eberhard Grube, Lars Lickfett, Georg Nickenig, Jan Malte Sinning, Nikos Werner Guest operators: Lutz Buellesfeld, Marco Wainstein On-line factoids relevant to the cases presented: Alaide Chieffo, Francesco Arioli, Alfonso Ielasi 18.15-20.15 Cocktail Symposia Friday, February 11th, 2011 18.15-20.15 Cocktail Symposium - ROOM MICHELANGELO ADVANCES IN TAVI 2011 (PART 2) Chairmen: Ted Feldman, Joachim Schofer 18.15 Direct Flow Medical, Advancement of a repositionable, retrievable percutaneous aortic valve Klaudija Bijuklic 18.35 Jena Valve FIM-transapical data Ardawan Rastan 18.55 The Sadra Medical Lotus valve system Ted Feldman 19.15 Update on the HLT Transcatheter Valve Robert Wilson 19.35 Questions & Answers 18.15-20.30 Cocktail Symposium - ROOM TIZIANO CTO, BIFURCATION AND LEFT MAIN SELECTED CASES WITH COMMENTS BY THE MASTERS Chairmen: Alfredo Galassi, Eulogio Garcia CTO 18.15 Case 1 Masahiko Ochiai 18.25 Case 2 Etsuo Tsuchikane 18.35 Case 3 Alfredo Galassi 18.45 Questions & Answers BIFURCATION 19.00 Case 1 Fausto Feres 19.10 Case 2 Liliana Grinfeld 19.20 Case 3 Giuseppe Massimo Sangiorgi 19.30 Questions & Answers LEFT MAIN 19.45 Case 1 Franz-Josef Neumann 19.55 Case 2 David Antoniucci 20.05 Case 3 Huay Cheem Tan 20.15 Questions & Answers 18.15-20.15 Cocktail Symposium - ROOM GIOTTO PERIPHERAL: SELECTED CASES Chairmen: Robert M. Bersin, Barry Katzen 18.15 My worst peripheral case Giuseppe Massimo Sangiorgi 18.30 Selected femoral and iliac cases Robert M. Bersin 18.45 Renal artery denervation for resistant hypertension Horst Sievert 19.00 Selected aortic aneurysm cases Barry Katzen 19.15 Selected carotid stent cases Issam Moussa 19.30 Vascular access closure device: from experimental to the clinical use Alessandro Bortone 19.45 Questions & Answers 20 21

Saturday, February 12th, 2011 7.00-8.00 Breakfast Symposium - ROOM GIOTTO ANTITHROMBOTIC PROTECTION FOR HIGH RISK PCI Chairman: Antonio Colombo 7.00 Introduction Antonio Colombo 7.05 Targeting the activated thrombin. Platelet pathway in high risk populations. Targeted therapies for improved outcomes Dominick Angiolillo 7.20 Improving outcomes in high risk NSTEMI ACS PCI George Dangas 7.35 Optimal management of STEMI: the crossroad of outcomes and bleeding Giuseppe Massimo Sangiorgi 7.50 Questions & Answers MAIN HALL LEONARDO Chairmen of the day: Antonio Colombo, Eberhard Grube 8.30-9.00 TWO SELECTED TAPED CASES Presented by Marie Claude Morice 9.00-10.00 LIVE CASES FROM LONDON, UK Royal Brompton & Harefield NHS Trust Commentators: Carlo Briguori, Fausto Feres, Achille Gaspardone, Francesco Maisano, Anil Potdar, Gerhard Schuler Operators: Carlo Di Mario, Kevin Beatt, Simon Davies, Ranil De Silva, Olaf Franzen, Neal Moat Guest operator: Osamu Katoh On-line factoids relevant to the cases presented: Alaide Chieffo, Francesco Arioli, Alfonso Ielasi Saturday, February 12th, 2011 10.00-11.40 CASES PRESENTATION Presented by the guest Faculty and Attendants Chairmen: Antonio Colombo, Eberhard Grube Tiziana Claudia Aranzulla Carlo Briguori, Gabriella Visconti Salvatore Curello Fotios Economou, Antonios Ziakas Shinichi Furuichi Azeem Latib Sanjay Mehrotra Emanuele Meliga Alberto Menozzi Wataru Nagamatsu Asif Qasim Andrea Pacchioni, Bernhard Reimers Joanne Shannon Turin - Italy Naples - Italy Brescia - Italy Thessaloniki - Greece Tokyo - Japan Milan - Italy Bangalore - India Turin - Italy Parma - Italy Osaka - Japan London - UK Mirano, VE - Italy Milan - Italy 11.40-12.10 TWO SELECTED TAPED CASES Presented by Antonio Colombo & Eberhard Grube 12.10-13.00 LIVE CASES FROM LONDON, UK Royal Brompton & Harefield NHS Trust Commentators: Omer Goktekin, Patrizia Presbitero, Gennaro Sardella, Huay Cheem Tan, Gian Paolo Ussia, Francesco Versaci Operators: Carlo Di Mario, Kevin Beatt, Simon Davies, Ranil De Silva, Olaf Franzen, Neal Moat Guest operator: Osamu Katoh On-line factoids relevant to the cases presented: Alaide Chieffo, Francesco Arioli, Alfonso Ielasi 13.00 Closing remarks and JIM 2012 announcement 22 23

Poster Session JIM 2011 Scientific Committee have selected the following posters: P1. Role of intracardiac echocardiography during percutaneous edge to edge mitral valve repair with the MitrClip system. A single centre experience. Marco Barbierato, Giuseppe Grassi, Federico Ronco, Andrea Pascotto, Stefano Postorino, Paolo Millosevich, Fausto Rigo, Daniele Penzo, Elvio Polesel, Antonio Raviele P2. Long-term outcome after drug-eluting stent implantation in patients undergoing primary percutaneous coronary intervention Yun-Kyeong Cho, Ji-Hyun Son, Hyoung-Seob Park, Hyuck-Jun Yoon, Hyungseop Kim, Chang-Wook Nam, Seung-Ho Hur, Yoon-Nyun Kim, Kwon-Bae Kim P3. Randomized Comparison of a Polymer-Free Sirolimus-Eluting Stent versus a Polymer-Based Paclitaxel-Eluting Stent in Patients with Diabetes Mellitus: The LIPSIA Yukon Trial Steffen Desch, Denis Schloma, Sven Möbius-Winkler, Sandra Erbs, Stephan Gielen, Axel Linke, Jiangtao Yu, Bernward Lauer, Klaus Kleinertz, Wilfried Dänschel, Gerhard Schuler, Holger Thiele P4. Endovascular Therapy for CTO of Superficial Femoral Artery of A Chronic Kidney Disease Patient under Carbon Dioxide Angiography Taku Iwaki, Takanobu Mitarai, Rie Sasaki, Kei Yamamoto, Yuya Kimura, Hiromasa Katoh, Tsuyoshi Nozue, Ichiro Mizuguchi, Ichiro Michishita P5. Mechanisms of Lumen Gain in Bifurcation Lesions: IVUS Comparison of Self-expanding Sideguard Sidebranch Versus Balloon-Expandable Main Vessel Stents Shixin Ma, Akiko Maehara, Karl E Hauptmann, Giulio Guagliumi, Orazio Valsecchi, Angelina Vassileva, Yolande Appelman, Giuseppe Sangiorgi, Francesco Prati, Gary S Mintz Poster Session P6. Femoral artery angiography can reduce vascular complications Takeshi Onizuka, Akio Kawamura, Shigetaka Noma P7. The impact of patient and lesion complexity on clinical and angiographic outcomes following revascularization with zotarolimus-eluting and everolimus-eluting stents: a sub-study of the resolute all comers trial Giulio G. Stefanini, Patrick W. Serruys, Sigmund Silber, Ahmed A. Khattab, Robert J. van Geuns, Gert Richardt, Pawel E. Buszman, Henning Kelbæk, Adrianus J. van Boven, Sjoerd H. Hofma, Axel Linke, Volker Klauss, William Wijns, Carlos Macaya, Philippe Garot, Carlo Di Mario, Ganesh Manoharan, Ran Kornowski, Thomas Ischinger, Antonio L. Bartorelli, Pierre Gobbens, Stephan Windecker P8. Rotational atherectomy in-hospital and long-term follow up Marcin Wojtczak, Wojciech Zimoch, Krzysztof Reczuch P9. Comparison of long term clinical and angiographic outcomes following implantation of bare metal stents and drug-eluting stents in aorto-ostial lesions Rasha Al-Lamee, Alfonso Ielasi, Azeem Latib, Cosmo Godino, Marco Mussardo, Francesco Arioli, Filippo Figini, Daniela Piraino, Mauro Carlino, Matteo Montorfano, Alaide Chieffo, Antonio Colombo P10. Preliminary experience with optical coherence tomography imaging to evaluate carotid artery stents: safety, feasibility, and technique Bernhard Reimers, Dimitrios Nikas, Andrea Pacchioni, Luca Favero, Eugenio Stabile, Salvatore Saccà, Alberto Cremonesi, Paolo Rubino Posters will be displayed in the Congress Area throughout the Meeting. Poster set up and removal - Set up on Thursday, February 10th from 10.45 to 12.30 - Remove on Saturday, February 12th, by 14.00 24 25

Don t miss Scientific Information Language English is the official language of the Congress. No simultaneous translation is available. Cases presentation and Posters Recorded procedures Have a chance to show your best success or to discuss your worst complications in front of an outstanding panel in the Main Arena. Saturday morning will be devoted to cases review (7 minutes each, including Q&A) from Faculty and Attendance. Posters Selected posters will be displayed in the Congress Area throughout the Meeting. Computer Center A Computer Center will be available in the Congress Area. To allow a smooth running of sessions, Speakers are requested to contact this center and hand in their presentation at least one hour before the beginning of their session or the previous afternoon for the morning sessions. TV direction and coordination by Mr. Sandro Alli Coordination of technical equipment by Mr. Paolo Torreggiani - LVS Solution Website by Airon Telematica EDP management by InforTeam srl 26 27

General Information General Information Organizing Secretariat Victory Project Congressi Via C. Poma, 2-20129 Milan - Italy Phone: +39 02.89.05.35.24 Fax: +39 02.20.13.95 e-mail: info@victoryproject.it Piazza Navona Secretariat on Site Secretariat and Registration Desk at Congress Venue will be on duty from February 9 through 12. Opening hours February 9 17.00-19.00 February 10 7.15-21.00 February 11 7.15-20.30 February 12 6.45-13.00 Coffee and refreshment Coffee and refreshment will be organized in the Exhibition area. Lunch Buffet for Exhibitors Buffet lunch will be served in Room Tintoretto (ground floor) upon presentation of the daily ticket. Rome by night Symposia for Physicians, Industry Professionals, Fellows and Nurses Symposia will be organized in Room Michelangelo, Room Tiziano and Room Giotto upon presentation of the daily ticket (food and beverages included). Reminder: all those interested in LUNCH SYMPOSIA are requested to collect the relevant ticket at the Lunch Symposia Registration Desk (from 9.00 to 12.00 of the same day). Coupons for each symposium will be limited to the availability of room seats. Certificate of attendance A certificate of attendance will be given to all registered participants upon presentation of their badge at the Secretariat Desk on Saturday, February 12, 2011. 28 29

Accreditation EBAC CME Accreditation The Joint Interventional Meeting JIM 2011 is accredited by the European Board for Accreditation in Cardiology (EBAC) for 15 hours of external CME credits. Each participant should claim only those hours of credit that have actually been spent in the educational activity. EBAC works according to the quality standards of the European Accreditation Council for Continuing Medical Education (EACCME), which is an institution of the European Union of Medical Specialists (UEMS). In compliance with EBAC/EACCME guidelines, all speakers/chairpersons participating in this program have disclosed or indicated potential conflicts of interest which might cause a bias in the presentations. The Organizing Committee/Course Director is responsible for ensuring that all potential conflicts of interest relevant to the Programme are declared to tha audience prior to the CME activities. Registration Registration fees Physician 900,00 Fellow, nurse, technician 320,00 Industry Professional (not having a stand) 900,00 Exhibitor (having a stand) 465,00 (prices are in Euro and include VAT) The full registration fee for Physician, Industry Professional, Fellow, Nurse and Technician includes: Admission to all Scientific Sessions Coffee and refreshment Entrance to the Exhibition Congress kit All Symposia (lunch included) The registration fee for Exhibitor includes: Admission to the Scientific Sessions (Symposia excluded) Coffee and refreshment Buffet lunch Entrance to the Exhibition Congress kit Only registered participants are allowed to attend the scientific sessions. Participants are requested to wear their badge for all the Congress events. ECM for Italian Participants The program of JIM 2011 has been submitted for accreditation for Italian Continuing Medical Education (ECM). ERGIFE Palace Hotel CME/ECM instructions Participants attendance will be registered by magnetic badge. At the registration desk, you will be handled evaluation forms and a personal TAG. At the end of the Meeting, you will have to return all documentation, duly filled in, together with the TAG. Should you not return the TAG, you will loose your credits and you will be charged e 7,00. 30 31

Hotel Map Congress Area Map 5 2 3 4 WARDROBE BAR GROUND FLOOR BAR 1 43 44 JIM ERGIFE Palace Hotel FIRST UNDERGROUND FLOOR 18 23 20 1 Crowne Plaza Rome St. Peter s 2 Grand Hotel Tiberio 3 NH Leonardo da Vinci 4 NH Vittorio Veneto 5 The Duke Hotel SECOND UNDERGROUND FLOOR 32 33

Meeting Rooms and Exhibition Map Meeting Rooms and Exhibition Map WARDROBE BAR BAR 34 35

Meeting Rooms and Exhibition Map Meeting Rooms and Exhibition Map 43 44 18 23 20 36 37

Meeting Rooms and Exhibition Map Exhibitors Exhibitor Stand ABBOTT VASCULAR 25 AGA MEDICAL 42 AMS- Advanced Medical Supplies 14 ASAHI - INTECC 10 BIOSENSORS INTERNATIONAL 33 BIOTRONIK 7, 8 & 9 BLUE MEDICAL DEVICES 37 BOSTON SCIENTIFIC 31 CARDIOLINK 20 CASCINA PASTORI - Wine Corner CID 3 & 4 CORDIS, a Johnson & Johnson Company 26 EBIT-AET, an ESAOTE Business Unit 1 & 2 EDI ERMES B EDIZIONI MINERVA MEDICA A EDWARDS LIFESCIENCES 27 ENDOTECH 29 FONDAZIONE EVIDENCE - M.C.R. 32 FUTURE MEETINGS 44 GAMMA INTERNATIONAL 35 38 39

Exhibitors Acknowledgements Exhibitor Stand Thanks to: GISE - Società Italiana di Cardiologia Interventistica 39 HEXACATH 21 KARDIA 11,12 & 13 MAQUET 40 & 41 MEDRAD EUROPE 17 MEDTRONIC 28 OCCLUTECH INTERNATIONAL 36 ORBUSNEICH 16 PHILIPS HEALTHCARE 18 ROME HEART RESEARCH SIS MEDICAL - MEDICAL INSTRUMENTS 15 SPECTRANETICS 38 ST. JUDE MEDICAL 5 & 6 STENTYS 34 TCT MEDITERRANEAN 43 TERUMO EUROPE 24 VOLCANO 30 WISEPRESS 22 & 23 C ABBOTT VASCULAR ADVANCED MEDICAL SUPPLIES AGA MEDICAL ARDIAN ASAHI-INTECC ATRIUM MEDICAL CORPORATION BIBA MEDICAL BIOSENSORS INTERNATIONAL BIOTRONIK BLUE MEDICAL DEVICES BOSTON SCIENTIFIC CAPPELLA MEDICAL DEVICES CARDIAC DIMENSIONS CID CORDIS DAIICHI SANKYO DIRECT FLOW MEDICAL EBIT-AET, an ESAOTE Business Unit EDWARDS LIFESCIENCES ELI LILLY ITALIA ENDOTECH EUROCOR GAMMA INTERNATIONAL GDS - GUIDED DELIVERY SYSTEMS HEARTLEAFLET HEXACATH JENA VALVE KARDIA MAQUET MEDICAL INSTRUMENTS MEDRAD EUROPE MEDTRONIC MITRALIGN OCCLUTECH INTERNATIONAL ORBUSNEICH PHILIPS HEALTHCARE SADRA MEDICAL SIS MEDICAL SPECTRANETICS STENTYS ST. JUDE MEDICAL TERUMO EUROPE THE MEDICINES COMPANY VASCULAR CLOSURE SYSTEMS VOLCANO 40 41

Major Sponsors The Directors of the Course particularly wish to thank for their support in the organization of JIM 2011: Major Sponsors They also express their gratitude to: 42 43

Organizing Secretariat VICTORY PROJECT CONGRESSI Via C. Poma, 2 20129 Milano Italy Phone +39 02 89 05 35 24 Fax +39 02 20 13 95 e-mail info@victoryproject.it www.studio-segre.it DON T MISS ROME, ITALY FEBRUARY 9-11, 2012 44