SUBSIDIARIES. Janssen Pharmaceuticals, Inc.



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SUBSIDIARIES EXHIBIT 21 Johnson & Johnson, a corporation, had the domestic and international subsidiaries shown below as of December 30, 2012. Certain U.S. subsidiaries and international subsidiaries are not named because they were not significant in the aggregate. Johnson & Johnson has no parent. Name of Subsidiary U.S. Subsidiaries: Acclarent, Inc. ALZA Corporation Animas Corporation Biosense Webster, Inc. CNA Development LLC Codman & Shurtleff, Inc. Cordis Corporation Cordis International Corporation Cordis LLC DePuy Mitek Holding Corporation DePuy Mitek, LLC DePuy Orthopaedics, Inc. DePuy Products, Inc. DePuy Spine, LLC DePuy Synthes Sales, Inc. DePuy Synthes, Inc. Diabetes Diagnostics, Inc. Ethicon Endo-Surgery, Inc. Ethicon Endo-Surgery, LLC Ethicon LLC Ethicon US, LLC Ethicon, Inc. ISO Holding Corp. J&J Holdings (Nevada), Inc. Janssen Alzheimer Immunotherapy Research & Development, LLC Janssen Biotech, Inc. Janssen Global Services, LLC Janssen Oncology, Inc. Janssen Ortho LLC Janssen Pharmaceuticals, Inc. Janssen Products, LP Janssen Research & Development, LLC Janssen Scientific Affairs, LLC Janssen Services, LLC Janssen Supply Group, LLC Janssen-Cilag Manufacturing, LLC JJHC, LLC JNJ International Investment LLC Johnson & Johnson (Middle East) Inc. Johnson & Johnson Consumer Companies, Inc. Johnson & Johnson Development Corporation Johnson & Johnson Finance Corporation Johnson & Johnson Health Care Systems Inc. Johnson & Johnson International Johnson & Johnson Inc. Johnson & Johnson Sales and Logistics Company, LLC Johnson & Johnson Services, Inc. Johnson & Johnson Urban Renewal Associates California Massachusetts Indiana Indiana Ohio Massachusetts Texas Nevada Pennsylvania Pennsylvania Pennsylvania

Johnson & Johnson Vision Care, Inc. JOM Pharmaceutical Services, Inc. LifeScan LLC LifeScan Products, LLC LifeScan, Inc. McNeil Consumer Pharmaceuticals Co. McNeil Healthcare LLC McNeil LA LLC McNEIL MMP, LLC McNeil Nutritionals, LLC McNEIL-PPC, Inc. Mentor Texas L.P. Mentor Worldwide LLC Micro Typing Systems, Inc. Micrus Endovascular LLC Middlesex Assurance Company Limited Neutrogena Corporation Nitinol Development Corporation Noramco, Inc. OMJ Pharmaceuticals, Inc. Omrix Biopharmaceuticals, Inc. Ortho Biologics LLC Ortho-Clinical Diagnostics, Inc. Refresh Holdings, Inc. Rutan Realty LLC Scios Inc. SterilMed, Inc. Synthes USA Products, LLC Synthes USA, LLC Synthes, Inc. The Anspach Effort, LLC Wellness & Prevention, Inc. International Subsidiaries: Almaco Holding AG Apsis Apsis GmbH Beijing Dabao Cosmetics Co., Ltd. Berna Biotech Korea Corporation Berna Rhein B.V. Biosense Webster (Israel) Ltd. Cilag Advanced Technologies GmbH Cilag AG Cilag GmbH International Cilag Holding AG Cilag Pharmaceuticals GmbH Cordis California Vermont California Georgia New York Minnesota Michigan Israel

Cordis de, S.A. de C.V. Cordis Europa NV Cordis Medizinische Apparate GmbH Corimmun GmbH Crucell Holland B.V. Crucell N.V. Crucell AB Crucell AG DePuy () DePuy DePuy International (Holdings) Limited DePuy International Limited DePuy Medical Private Limited DePuy Mitek Sarl DePuy Motion Sarl DePuy Orthopadie GmbH DePuy UK Holdings Limited EES Holdings de, S. de R.L. de C.V. Ethicon Ethicon Ethicon PR Holdings Ethicon Women's Health & Urology Sarl Ethnor Farmaceutica, S.A. FMS Future Medical System SA GMED Healthcare BVBA High Wycombe Property Management Limited J.C. General Services CVBA Janssen Alzheimer Immunotherapy Janssen Alzheimer Immunotherapy (Holding) Limited Janssen Biologics () Janssen Biologics B.V. Janssen Cilag Farmaceutica S.A. Janssen de S. de R.L. de C.V. Janssen Inc. Janssen Infectious Diseases-Diagnostics BVBA Janssen Korea Ltd. Janssen Pharmaceutica NV Janssen Pharmaceutical Janssen Pharmaceutical Holdings Janssen Pharmaceutical K.K. Janssen R&D Janssen-Cilag Janssen-Cilag AB Janssen-Cilag AG Janssen-Cilag B.V. Janssen-Cilag Farmaceutica Ltda. Janssen-Cilag Farmaceutica, Lda. Janssen-Cilag GmbH India Argentina Canada Portugal

Janssen Cilag Limited Janssen-Cilag Limited Janssen-Cilag NV Janssen-Cilag OY Janssen-Cilag Pharma GmbH Janssen-Cilag Pharmaceutical S.A.C.I. Janssen-Cilag Pty Ltd Janssen-Cilag S.p.A. Janssen-Cilag, C.A. Janssen-Cilag, S.A. Janssen-Cilag, S.A. de C.V. J-C Health Care Ltd. JJC Acquisition Company B.V. Johnson & Johnson () Investment Ltd. Johnson & Johnson () Ltd. Johnson & Johnson (Hong Kong) Limited Johnson & Johnson () Limited Johnson & Johnson (New Zealand) Limited Johnson & Johnson (Philippines), Inc. Johnson & Johnson (Proprietary) Limited Johnson & Johnson (Thailand) Ltd. Johnson & Johnson AB Johnson & Johnson AG Johnson & Johnson Consumer (Thailand) Limited Johnson & Johnson Consumer B.V. Johnson & Johnson Consumer Holdings Johnson & Johnson Consumer Services EAME Ltd. Johnson & Johnson de Argentina S.A.C. e. I. Johnson & Johnson de Chile S.A. Johnson & Johnson de Colombia S.A. Johnson & Johnson de, S.A. de C.V. Johnson & Johnson de, S.A. Johnson & Johnson del Ecuador S.A. Johnson & Johnson del Peru S.A. Johnson & Johnson do Brasil Industria E Comercio de Produtos Para Saude Ltda. Johnson & Johnson European Treasury Company Johnson & Johnson Finance Limited Johnson & Johnson Financial Services GmbH Johnson & Johnson Gesellschaft m.b.h. Johnson & Johnson GmbH Johnson & Johnson Group Holdings GmbH Johnson & Johnson Hellas Commercial and Industrial S.A. Johnson & Johnson Holding GmbH Johnson & Johnson Inc. Johnson & Johnson Industrial Ltda. Johnson & Johnson International Financial Services Company Johnson & Johnson K.K. Johnson & Johnson Kft. Thailand Finland Austria Greece Spain Israel Hong Kong New Zealand Philippines South Africa Thailand Thailand Argentina Chile Colombia Ecuador Peru Austria Greece Canada Hungary

Johnson & Johnson Korea Selling & Distribution Limited Liability Company Johnson & Johnson Korea, Ltd. Johnson & Johnson Limitada Johnson & Johnson Limited Johnson & Johnson Limited Johnson & Johnson LLC Johnson & Johnson Finance Company Sarl Johnson & Johnson Management Limited Johnson & Johnson Medical () Ltd. Johnson & Johnson Medical (Pty) Limited Johnson & Johnson Medical (Shanghai) Ltd. Johnson & Johnson Medical (Suzhou) Ltd. Johnson & Johnson Medical B.V. Johnson & Johnson Medical GmbH Johnson & Johnson Medical Korea Limited Johnson & Johnson Medical Limited Johnson & Johnson Medical, S.A. de C.V. Johnson & Johnson Medical NV Johnson & Johnson Medical Products GmbH Johnson & Johnson Medical Pty Ltd Johnson & Johnson Medical S.A. Johnson & Johnson Medical S.p.A. Johnson & Johnson Medical, S.C.S. Johnson & Johnson Middle East FZ-LLC Johnson & Johnson Pacific Pty. Limited Johnson & Johnson Poland Sp. z o.o. Johnson & Johnson Pte. Ltd. Johnson & Johnson Pty. Limited Johnson & Johnson S.p.A. Johnson & Johnson SDN. BHD. Johnson & Johnson Sihhi Malzeme Sanayi Ve Ticaret Limited Sirketi Johnson & Johnson Swiss Finance Company Limited Johnson & Johnson Taiwan Ltd. Johnson & Johnson Vision Care () Johnson & Johnson, prodaja medicinskih in farmacevtskih izdelkov, d.o.o. Johnson & Johnson, S.A. Johnson & Johnson, S.A. de C.V. Johnson & Johnson, s.r.o. Latam International Investment Company Latam Properties Holdings LifeScan Scotland Limited McNeil AB McNeil GmbH & Co. ohg McNeil Healthcare (UK) Limited McNeil Manufacturing Pty Ltd McNeil Products Limited McNeil AB Portugal India Russian Federation South Africa Austria Argentina United Arab Emirates Poland Singapore Malaysia Turkey Taiwan Slovenia Spain Czech Republic

Medos International Sarl Medos Sarl Mentor Medical Systems B.V. Mentor Medical Systems C.V. OBTECH Medical Sarl OMJ OMJ PR Holdings Omrix Biopharmaceuticals Ltd. Ortho-Clinical Diagnostics Ortho-Clinical Diagnostics Ortho-Clinical Diagnostics GmbH Ortho-Clinical Diagnostics K.K. Ortho-Clinical Diagnostics NV P.T. Johnson & Johnson Indonesia Shanghai Johnson & Johnson Pharmaceuticals, Ltd. Synthes (Shanghai) Medical Trading Co., Ltd. Synthes (Suzhou) Medical Co., Ltd. Synthes Pty Ltd Synthes Canada, Ltd. Synthes Colombia S.A.S. SYNTHES Deutschland Holding GmbH Synthes Finanz AG SYNTHES GmbH Synthes GmbH Synthes Holding AG Synthes Industria e Comercio Ltda. Synthes K.K. Synthes Limited Synthes Lux Finance S.àr.l. Synthes Lux Holding S.àr.l. Synthes, S.àr.l. Synthes Medical Private Limited Synthes Produktions GmbH Synthes S.r.l. Synthes Tuttlingen GmbH Synthes-Stratec S.A. Tasmanian Alkaloids Pty. Ltd. Tibotec-Virco Comm. VA Turnbuckle Investment Company Vania Expansion Xian-Janssen Pharmaceutical Ltd. Israel Indonesia Canada Colombia India Spain