Developing Smart Physician/Patient Decision Support Healthcare System

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Developing Smart Physician/Patient Decision Support Healthcare System Daniel Cane and Michael Sherling, Modernizing Medicine Borko Furht, Taghi Khoshgoftaar, Ankur Agarwal, and Hari Kalva Florida Atlantic University

HISTORY The Center established at FIU, 2008 FAU Site established in 2009 Dubna University (Moscow, Russia) joined the Center in 2011 as a foreign site FAU Site has 29 industry members FAU Funding: ~$800,000 from NSF and ~2.6 million from industry memberships 40 industry projects; 16 faculty and 70 students ~ 60 publications and 6 patent disclosures

Modernizing Medicine History Established in 2010 Daniel Cane Technology entrepreneur Co-founder of Blackboard IPO 2003 (NASDAQ: BBBB) Sold in 2010 for $1.6B Dr. Michael Sherling MD/MBA Yale Chief Resident and Faculty at Harvard Board Certified Dermatologist

Electronic Medical Assistant Developed by Modernizing Medicine Cloud-based specific Electronic Medical Record system with a large library of built-in medical content Designed to increase physician s efficiency and improve outcomes EMA data include: patient demographics, medical history and family history, coded diagnoses and procedures based on billing codes, and outcomes and medication data collected during patent encounters EMA Dermatology EMA Ophthalmology EMA Orthopedics EMA Otolaryngology (ENT) EMA Plastic Surgery EMA Cosmetic Surgery EMA Gastroenterology EMA Urology EMA Rheumatology (in development)

Physician s Interface with EMA This is physicians vision of what one should be Created by physicians for physicians Modernizing Medicine has 17 physicians as full-time employees

Virtually Anytime, Anywhere Connection EMA

EMAzing Growth 1,500 practices and 4,000+ providers Approximately 22% of dermatology market

Total Visits in EMA by Quarter 14 million total visits from January 1, 2010 to March 31, 2014

6856605 L97.311 271737000 Structured Data EMA goes beyond a simple collector of static clinical data S62.606P S01.111A 4545-0 C44.191 B35.3 62241-5 T15.12XS S90.461A L97.311 H34.811 C4A.22 S05.12XA 55781-9 21522001

EMA Network The Data Revolution 32 million+ procedures nationally and growing exponentially from more than 3,000 providers 100% structured, de-identified and aggregated data Native ipad application functions as efficient clinical Electronic Data Capture platform Cloud-based technology and adaptive learning ensure up-to-date data

EMA Outcomes Visualize Patient Data Over Time Powered by the EMA Network, EMA Outcomes displays, with the simple touch of a button, a visual timeline that tracks a patient s disease or condition. Easily determine if conditions are improving or declining Visualize clinical trends, treatments and outcomes longitudinally to enable data driven decision-making Stop flipping through paper charts

EMA Grand Rounds Wisdom of the Masses EMA Grand Rounds instantly analyses and synthesizes clinical data across the entire EMA Network. Trend diseases, their outcomes and efficacy of treatments across a continuum to understand what is and is not working for you and your peers Gain instant access to disease specific popular treatments in clinical context Understand 3rd, 4th and 5th lines of treatment for common and rare diseases https://www.modmed.com/ophthalmolo gy/

Modernizing Medicine Awards 2014 Red Herring 100 2014 emerge Techweek Launch Competition Winner 2014 Sun Sentinel Excalibur Award, Daniel Cane 2014 US Chamber of Commerce Small Business Finalist (Regional winner) 2013 America's Most Promising Companies, Forbes, #47 2013 Fastest Growing Company/Fast 50, SFBJ, #1 2013 Influential Business Woman of the Year for Karen O Byrne, South Florida Business Journal (SFBJ) 2013 40 Under 40 Award for Michael Sherling, MD, SFBJ 2013 Palm Beach Ultimate CEO Award for Daniel Cane 2013 Best Places to Work, SFBJ, #2 2013 Health Care Innovation Hero, Palm Beach County Medical Society Services 2013 Governor's Innovators Under 40 Award, Florida Governor Rick Scott 2012 Top Mobile Startup in South Florida, South Florida Technology Alliance (SFTA), #1 2012 Florida Companies to Watch Award, Florida Economic Gardening Institute (GrowFL) 2012 40 Under 40 Award for CEO Daniel Cane, SFBJ 2012 Fastest Growing Company/Fast 50, SFBJ, #1 2012 Business of the Year, SFBJ 2012 H. Wayne Huizenga Startup Award, SFBJ 2011 Entrepreneur Award - Best Startup, SFBJ

Company Accolades One of America s Most Promising Companies #1 Fastest Growing Company Fast 50 (2012 & 2013) Best Places to Work US Chamber of Commerce Small Business of the Year Blue Ribbon Winner & Regional Finalist One of the Best Places to Work in Healthcare One of Top 100 Best Companies, Florida Trend

The EMA Summary By Surgeons for Medical Practices Built-in medical knowledge and coding expertise EMA 3-D Interactive Anatomical Atlas Remembers Physician s Preferences Learns how physicians practice No macros, no templates, no hassle Easy-to-use Technology Touch-based data input Native ipad app Available from any web-enabled Mac or PC Cloud-based Requires no on-site server install and maintenance Access records virtually anywhere, anytime

New Project: Beyond EMA Partnership and Their Expertise

Architecture of the Electronic Medical Assistant

Architecture of Smart Decision Support Healthcare System

Objectives Develop data mining, machine learning, big data analytics, and data visualization techniques and tools to: Determine patient characteristics, risk factors, and disease severity associated with subsequent clinical response to treatment Determine a range of treatments including topical, phototherapy, and systematic therapies Analyze cost models and patient outcomes. Patient outcomes will be measured using validated methods, such as Physician Global assessment (PGA) and Body Surface Area (BSA)

Summary of Innovations