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1 Supplementary webappendix This webappendix formed part of the original submission and has been peer reviewed. We post it as supplied by the authors. Supplement to: Montalescot G, Zeymer U, Silvain J, et al, for the ATOLL Investigators. Intravenous enoxaparin or unfractionated heparin in primary percutaneous coronary intervention for ST-elevation myocardial infarction: the international randomised open-label ATOLL trial. Lancet 2011; 378:

2 Appendix The following investigators participated in the ATOLL trial: Steering Committee Dr. G. Montalescot (Chair, France) and Dr. M. Cohen (USA), Dr. P. Goldstein (France), Dr. K. Huber (Austria), Dr. C. Pollack (USA), Dr. E. Vicaut (France), Dr. U. Zeymer (Germany) Data Monitoring Committee Dr. A. Cohen (Chair, France), Dr. M. Cucherat (Statistician, France), Dr. A. Gitt (Germany) Clinical Events Committee Dr. A. Bellemain-Appaix (France), Dr. F. Boccara (France), Dr. O. Gournay (France), Dr. F. Philippe (France), Dr. P. Sabouret (France) Angiographic and electrocardiographic core laboratory: Dr. R. Dumaine (Grands-Près Hospital, France) and Dr. A. Reza (Villeneuve-Saint-Georges Hospital) Key Sponsor (AP-HP), Academic Research Organization (ACTION), Unité de Recherche Clinique (URC Paris 7) and Coordinating Center (Institut de Cardiologie, Pitié-Salpêtrière Hospital) Personnel Ph. Gallula (Sponsor Coordinator), V. Gallois (Study Manager), S. Paulsrud (Study Assistant), B. Bertin (Study Coordinator), D. Brugier (Study Coordinator), N. Vignolles (Study Coordinator), M. Viaud-Courrèges (Clinical Director), and V. Jouis (Clinical Director).

3 Participating Investigators AUSTRIA: Wilhelminenhospital (Wien): Pr Huber, Dr Unger, Dr Nürnberg, Dr Geppert, Dr Jarai, Dr Bruno, Dr Freynhofer, Dr Leherbauer, Dr Pavlovic, Dr Vogel AKH Linz (Linz): Dr Leisch, Dr Grund, Dr Steinwender, Dr Hofmann, Dr Kammler, Dr Hönig, Dr Kerschner, Dr Kypta KH Rudolfstiftung (Wien): Pr Weidinger, Dr Jungbauer, Dr Krutisch LKH Feldkirch (Feldkirch): Dr Benzer FRANCE: Pitié-Salpêtrière Hospital, Cardiology Department (Paris): Pr Montalescot, Pr Collet, Dr. Silvain, Dr Barthélémy, Dr Beygui; SMUR (Paris): Dr Ecollan Hôpital Lariboisière, Cardiology Department (Paris): Pr Henry, Dr Dillinger; SMUR (Paris): Dr Broche, Dr S. Gallula Hôpital Necker, SAMU (Paris): Dr Greffet, Pr Carli Hôpital Cochin, Cardiology Department (Paris): Pr Spaulding, Dr Varenne, Dr Jegou, Dr Marque Hôpital Bichat, Cardiology Department (Paris): Pr Steg Hôpital Européen Georges Pompidou, Cardiology Department (Paris): Pr Danchin, Pr Durand Hôpital Henri Mondor, SAMU/SMUR (Créteil): Dr Margenet, Dr Combes, Dr. Le Roux ; Cardiology Department: Pr Teiger, Dr Bamabas Hôpital Avicenne SAMU (Bobigny): Pr Adnet, Dr Lapostolle CHI André Grégoire, Cardiology Department (Montreuil): Dr Payot

4 Hôpital Gilles de Corbeil Sud Francilien SAMU/SMUR (Corbeil-Essonnes): Pr Pouges, Dr Briole, Dr Garrigue, Cardiology Department: Dr Lardoux, Dr Goube, Dr Toussaint, Dr Berthier Centre Hospitalier de Lagny, Cardiology Department (Lagny-sur-Marne): Dr Elhadad,Dr Cohen, Dr Domniez, Dr Foucher, Dr Sfaxi. SMUR (Lagny-sur-Marne): Dr Stibbe, Dr Porcher Centre Hospitalier Victor Dupouy SMUR (Argenteuil): Dr Cuvier, Cardiology Department: Dr Duclos, Dr Belhamiche Hôpital René Dubos SAMU/SMUR (Cergy-Pontoise): Dr Gelée, Dr Dupas; Cardiology Department (Cergy-Pontoise): Dr Funck, Dr Guillard Hôpital Nord (Marseille), Cardiology Department: Pr Paganelli Hôpital de la Timone SAMU (Marseille): Pr Auffray ; Cardiology Department: Pr Bonnet, Dr Cuisset Polyclinique Beauregard Cardiology Department (Marseille): DrWittenberg Hôpital Henri Duffaut SAMU (Avignon): Dr Barberon ; Cardiology Department: Dr Pansieri, Dr Barnay CHU Carémeau, Cardiology Department (Nîmes): Pr Ledermann, Dr Cayla, Dr Schmutz, Dr Bertinchant, Pr Messner-Pellenc ; SAMU/SMUR (Nîmes): Dr Bénezet, Dr Assaf, Dr de la Coussaye Hôpital de Purpan SAMU (Toulouse): Dr Ducassé, Dr Charpentier ; Cardiology Department: Pr Carrié Hôpital Pellegrin SMUR (Bordeaux); Dr Thicoïpe, Dr Chauveau; Hôpital cardiologique du Haut Lévêque, Cardiology Department (Pessac): Pr Coste, Dr Leroux Hôpital Central SAMU (Nancy): Dr Chouihed ; Hôpitaux de Brabois, Cardiology Department (Vandoeuvre les Nancy): Dr Angioï, Dr Marcon

5 CH Bretagne Atlantique SAMU (Vannes): Dr Boulanger; Cardiology Department: Dr Filippi, Dr Mahe Hôpital Cavale Blanche SAMU (Brest): Dr Treuil, Cardiology Department: Pr Boschat, Dr Gilard Hôpital de Pontchaillou Cardiology (Rennes): Pr Le Breton ; SAMU (Rennes): Dr Courcoux CHIC de Cornouaille SAMU (Quimper): Dr Mehu ; Cardiology Department: Dr Joseph CHRU Lille SAMU (Lille): Dr Goldstein, Pr Asseman, Dr Adriansen ; Hôpital Calmette, Cardiology Department (Lille): Dr Ennezat, Dr Bauchart, Pr Lablanche CH Louis Pasteur Cardiology Department (Chartres): Dr Thuaire Hôpital du Bocage SAMU (Dijon): Pr Freysz, Dr Avondo-Lofti; Cardiology Department: Pr Cottin, Dr Cabrita Hôpital Européen de Paris La Roseraie, Institut Cardio-Vasculaire (Aubervilliers): Dr Salengro, Dr Jessen Hôpital de Mulhouse Chem SAMU (Mulhouse): Dr Wolff ; Cardiology Department: Dr Jacquemin CHI Le Raincy Cardiology Department (Montfermeil): Dr Nallet, Dr Cattan, Dr Michaud GERMANY: Herzzentrum Klinikum Ludwigshafen (Ludwigshafen): Pr Zeymer, Dr Zahn, Dr Klein, Dr Winkler, Dr Schiele Vivantes Klinikum Am Urban (Berlin): Pr Andresen, Dr. Hoffmann; Dr Drogaris, Dr Admovihadscho Klinikum Dorothea Christiane Erxleben Quedlinburg GmbH (Quedlinburg): Dr Fischer Klinikum Pirna (Pirna): Dr Axthelm, Dr Schein, Dr Funke

6 Klinikum Offenbach (Offenbach): Dr Girth, Dr Hauber, Dr Schmidt, Dr Hanika, Dr Heimann Krankenhaus der Barmherzigen Brüder Trier (Trier): Dr Hauptmann, Dr Gehrig USA: Newark Beth Israel Medical Center (Newark): Dr Cohen, Dr Adams St. Michael s Medical Center (Newark): Dr Shamoon, Dr Pennel, Dr Montel

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